oxytetracycline--anhydrous has been researched along with hydrocortisone-acetate* in 2 studies
2 other study(ies) available for oxytetracycline--anhydrous and hydrocortisone-acetate
| Article | Year |
|---|---|
External otitis caused by infection with Pseudomonas aeruginosa or Candida albicans cured by use of a topical group III steroid, without any antibiotics.
Irrespective of the microbial agent, group III steroid solution cured external otitis efficiently in a rat model. The addition of antibiotic components to steroid solutions for the treatment of external otitis is of questionable validity.. External otitis, caused by infection with either Pseudomonas aeruginosa or Candida albicans, was established in a rat model and the treatment efficacy of a group III steroid solution was studied.. Three treatments were studied: (i) a group III steroid solution; (ii) a group I steroid combined with two antibiotic components; and (iii) a saline solution. A scoring scale was used to evaluate the characteristics of the ear canal skin. Bacteriological and fungal samples were collected for culturing and ear canal skin biopsies were taken for structural analyses.. It was possible to cause P. aeruginosa and C. albicans infections in an animal model. In the P. aeruginosa-infected animals, only the group III steroid treatment cured all the animals. In the C. albicans-infected animals, group III steroid treatment resolved external otitis faster than the other treatment modalities. Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Betamethasone; Candidiasis; Colony-Forming Units Assay; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ear Canal; Hydrocortisone; Male; Otitis Externa; Oxytetracycline; Polymyxin B; Pseudomonas Infections; Rats; Treatment Outcome | 2005 |
[Extraction of components from hydrocortisone mixtures using high pressure thin layer chromatography ].
Chromatographic conditions for the separation of five pairs of active compounds occuring in four ointment preparations and an aerosol one were elaborated. The ways of extraction of hydrocortisone esters (acetate and butyrate), chlorquinaldol, oxytetracycline base and oxytetracycline hydrochloride from the ointments as well as purification of the extracts prior to the HPLC analysis were described. The proposed analytical methods are for more specific and precise from those used until now in the home-made preparations quality control. Topics: Aerosols; Chlorquinaldol; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hydrocortisone; Ointments; Oxytetracycline | 1990 |