Page last updated: 2024-09-02

oxymatrine and muscimol

oxymatrine has been researched along with muscimol in 3 studies

Compound Research Comparison

Studies
(oxymatrine)
Trials
(oxymatrine)
Recent Studies (post-2010)
(oxymatrine)
Studies
(muscimol)
Trials
(muscimol)
Recent Studies (post-2010) (muscimol)
410274,6999887
412162704,6999887

Protein Interaction Comparison

ProteinTaxonomyoxymatrine (IC50)muscimol (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0055
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0054
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.0032
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)0.016
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.0032
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.0032
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)0.016
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.0032
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)0.016
GABA theta subunitRattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)0.016
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0054
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)0.016

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, JX; Jiang, YX; Yan, L; Yang, G; Yi, ZH1
Gao, J; Jia, Y; Jiang, Y; Yan, L; Yang, G; Yu, J1
Dai, XY; Hao, YJ; Li, YX; Liu, HY; Sun, T; Wang, HY; Yu, JQ1

Other Studies

3 other study(ies) available for oxymatrine and muscimol

ArticleYear
[The influence of GABAA receptor on the analgesic action of intrathecally injected oxysophoridine].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:5

    Topics: Alkaloids; Analgesics; Animals; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Muscimol; Pain Threshold; Picrotoxin; Random Allocation; Receptors, GABA-A; Spinal Cord

2011
Oxysophoridine through intrathecal injection induces antinociception and increases the expression of the GABAAα1 receptor in the spinal cord of mice.
    Planta medica, 2012, Volume: 78, Issue:9

    Topics: Alkaloids; Analgesics; Animals; Bicuculline; Drug Evaluation, Preclinical; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Mice; Mice, Inbred ICR; Muscimol; Pain Measurement; Picrotoxin; Receptors, GABA-A; Spinal Cord

2012
Effects of oxymatrine on the neuropathic pain induced by chronic constriction injury in mice.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:12

    Topics: Alkaloids; Animals; Chronic Disease; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Muscimol; Neuralgia; Neuroprotective Agents; Nipecotic Acids; Oximes; Pain Measurement; Pain Threshold; Quinolizines; Receptors, GABA-A; Spinal Cord

2012