Page last updated: 2024-09-02

oxymatrine and morphine

oxymatrine has been researched along with morphine in 2 studies

Compound Research Comparison

Studies
(oxymatrine)
Trials
(oxymatrine)
Recent Studies (post-2010)
(oxymatrine)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
4102744,2705,2008,695
4121627044,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyoxymatrine (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Li, Y; Pan, Z; Sun, H; Xie, G; Xing, Y; Yue, H1

Other Studies

2 other study(ies) available for oxymatrine and morphine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Oxymatrine inhibits development of morphine-induced tolerance associated with decreased expression of P-glycoprotein in rats.
    Integrative cancer therapies, 2010, Volume: 9, Issue:2

    Topics: Alkaloids; Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Gene Expression Regulation; Male; Morphine; Pain; Quinolizines; Rats; Rats, Wistar

2010