oxymatrine has been researched along with lamivudine in 5 studies
| Studies (oxymatrine) | Trials (oxymatrine) | Recent Studies (post-2010) (oxymatrine) | Studies (lamivudine) | Trials (lamivudine) | Recent Studies (post-2010) (lamivudine) |
|---|---|---|---|---|---|
| 41 | 0 | 27 | 7,025 | 1,425 | 2,177 |
| 412 | 16 | 270 | 7,025 | 1,425 | 2,177 |
| Protein | Taxonomy | oxymatrine (IC50) | lamivudine (IC50) |
|---|---|---|---|
| Capsid protein | Hepatitis B virus | 0.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cen, S; Han, YX; He, HW; Hong, B; Jiang, JD; Kreiswirth, B; Li, BW; Li, ZR; Liu, F; Peng, ZG; Perlin, D; Shao, RG; Song, DQ; Sun, CH; Wang, YP; You, XF; Yu, LY; Zhao, LX | 1 |
| Bi, CW; Du, NN; Gao, LM; Han, YX; Jiang, JD; Li, X; Li, YH; Peng, ZG; Shan, YQ; Song, DQ; Wang, YP; Zhang, T | 1 |
| Cheng, W; He, LJ; Kuang, GK; Li, MM; Li, YL; Luo, D; Wang, GC; Yang, L; Zhang, YB | 1 |
| Cheng, YQ; Fu, JL; Lan, Y; Li, HW; Lou, M; Zhao, P | 1 |
| Cen, S; Chen, HS; Han, YX; Jiang, JD; Li, YH; Liu, F; Peng, ZG; Ren, G; Wang, YP; Xue, R; Zhao, W; Zhou, ZX | 1 |
1 trial(s) available for oxymatrine and lamivudine
| Article | Year |
|---|---|
[IFN or oxymatrine in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B].
Topics: Adult; Alkaloids; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Middle Aged; Quinolizines; Recombinant Proteins; Treatment Outcome | 2004 |
4 other study(ies) available for oxymatrine and lamivudine
| Article | Year |
|---|---|
Heat stress cognate 70 host protein as a potential drug target against drug resistance in hepatitis B virus.
Topics: 3' Untranslated Regions; Alkaloids; Antiviral Agents; Down-Regulation; Drug Design; Drug Resistance, Viral; Hepatitis B; Hepatitis B virus; Hepatocytes; HSC70 Heat-Shock Proteins; Humans; In Vitro Techniques; Quinolizines; RNA, Small Interfering; Virus Replication | 2010 |
Design and synthesis of oxymatrine analogues overcoming drug resistance in hepatitis B virus through targeting host heat stress cognate 70.
Topics: Administration, Oral; Alkaloids; Animals; Antiviral Agents; Down-Regulation; Drug Design; Drug Resistance, Viral; Hep G2 Cells; Hepatitis B virus; HSC70 Heat-Shock Proteins; Humans; Lamivudine; Lethal Dose 50; Mice; Molecular Conformation; Quinolizines; RNA, Messenger; Structure-Activity Relationship | 2011 |
Matrine-Type Alkaloids from the Roots of Sophora flavescens and Their Antiviral Activities against the Hepatitis B Virus.
Topics: Alkaloids; Antiviral Agents; Hepatitis B virus; Magnetic Resonance Spectroscopy; Mass Spectrometry; Matrines; Molecular Structure; Plant Roots; Quinolizines; Sophora; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; X-Ray Diffraction | 2018 |
Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance.
Topics: Administration, Oral; Adult; Alkaloids; Antiviral Agents; Biopsy; China; DNA, Viral; Down-Regulation; Drug Resistance; Drug Therapy, Combination; Female; Gene Expression Profiling; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HSC70 Heat-Shock Proteins; Humans; Lamivudine; Liver; Male; Middle Aged; Quinolizines; Treatment Outcome; Viral Load | 2011 |