oxymatrine has been researched along with chloroquine in 3 studies
| Studies (oxymatrine) | Trials (oxymatrine) | Recent Studies (post-2010) (oxymatrine) | Studies (chloroquine) | Trials (chloroquine) | Recent Studies (post-2010) (chloroquine) |
|---|---|---|---|---|---|
| 41 | 0 | 27 | 16,405 | 763 | 4,029 |
| 412 | 16 | 270 | 16,405 | 763 | 4,029 |
| Protein | Taxonomy | oxymatrine (IC50) | chloroquine (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 43 | |
| Spike glycoprotein | Betacoronavirus England 1 | 5.47 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 5.47 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 5.47 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0301 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 7 | |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2383 | |
| Procathepsin L | Homo sapiens (human) | 5.47 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 5.47 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | 3.58 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.375 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 1.5 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.27 | |
| Beta-secretase 1 | Homo sapiens (human) | 7 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.503 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 6.235 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.02 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Deng, CL; Li, XD; Wang, Z; Wei, HP; Xiao, SQ; Xiong, J; Yang, XL; Ye, HQ; Yuan, ZM; Zhang, B; Zhang, QY; Zhang, YN; Zhang, ZR | 1 |
| Luo, Y; Malewicz, N; Nie, H; Pan, J; Rong, J; Situ, Y; Tang, D; Verkhratsky, A; Wang, Y; Ye, K; Zhang, Z; Zhao, J; Zhu, T | 1 |
3 other study(ies) available for oxymatrine and chloroquine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture.
Topics: Alkaloids; Amaryllidaceae Alkaloids; Animals; Antiviral Agents; Betacoronavirus; Cell Survival; Chlorocebus aethiops; Chloroquine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Gemcitabine; Phenanthridines; SARS-CoV-2; Vero Cells; Virus Replication | 2020 |
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch.
Topics: Alkaloids; Animals; Antipruritics; Cell Membrane; Chloroquine; Chromatography; Disease Models, Animal; Drug Discovery; Ganglia, Spinal; Histamine; Humans; Isothiocyanates; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Oligopeptides; Phytotherapy; Plant Extracts; Pruritus; Quinolizines; RNA, Messenger; Sophora; TRPA1 Cation Channel | 2021 |