Compounds > oxymatrine
Page last updated: 2024-09-02

oxymatrine and apigenin

oxymatrine has been researched along with apigenin in 4 studies

Compound Research Comparison

Studies
(oxymatrine)		Trials
(oxymatrine)		Recent Studies (post-2010)
(oxymatrine)		Studies
(apigenin)		Trials
(apigenin)		Recent Studies (post-2010) (apigenin)
410273,273752,086
412162703,273752,086

Protein Interaction Comparison

ProteinTaxonomyoxymatrine (IC50)apigenin (IC50)
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein kinase II subunit alphaZea mays1.2
Chain A, Casein Kinase Ii Subunit AlphaZea mays1.2
Aldo-keto reductase family 1 member B10Homo sapiens (human)6.6
G2/mitotic-specific cyclin-B2Homo sapiens (human)4
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)3.1311
Estrogen receptorHomo sapiens (human)1.253
Cytochrome P450 1A1Homo sapiens (human)0.427
MyeloperoxidaseHomo sapiens (human)3.8
Cytochrome P450 1A2Homo sapiens (human)0.795
Cyclin-dependent kinase 1Homo sapiens (human)4
Beta-glucuronidaseRattus norvegicus (Norway rat)2.8
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.67
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.02
Androgen receptorHomo sapiens (human)5.2
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.94
AromataseHomo sapiens (human)3.275
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.71
Pyruvate kinase PKMHomo sapiens (human)0.99
G2/mitotic-specific cyclin-B1Homo sapiens (human)4
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.175
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.175
Casein kinase II subunit alpha'Homo sapiens (human)0.85
Amine oxidase [flavin-containing] AHomo sapiens (human)1.398
Amine oxidase [flavin-containing] BHomo sapiens (human)1.12
Dipeptidyl peptidase 4Homo sapiens (human)0.14
Proteasome subunit beta type-5Homo sapiens (human)1.4
Prostaglandin G/H synthase 2Homo sapiens (human)8
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)1.45
Tyrosine-protein kinase SYKHomo sapiens (human)4.2
Xanthine dehydrogenase/oxidaseHomo sapiens (human)1.95
Glycogen synthase kinase-3 alphaHomo sapiens (human)1.4
Glycogen synthase kinase-3 betaHomo sapiens (human)1.4
Mitogen-activated protein kinase 10Homo sapiens (human)2.2
Casein kinase II subunit betaHomo sapiens (human)0.85
Casein kinase II subunit alphaHomo sapiens (human)0.84
Xanthine dehydrogenase/oxidaseBos taurus (cattle)3.57
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)7
Cyclin-dependent kinase 6Homo sapiens (human)2.08
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.06
Cyclin homologHerpesvirus saimiri (strain 11)2.175
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.06
Mitogen-activated protein kinase 14Homo sapiens (human)2.2
Cytochrome P450 1B1Homo sapiens (human)0.1925
Integrase Human immunodeficiency virus 11.5
Casein kinase II subunit alpha 3Homo sapiens (human)0.8
G2/mitotic-specific cyclin-B3Homo sapiens (human)4
Estrogen receptor betaHomo sapiens (human)0.13
Aurora kinase BHomo sapiens (human)3.96
NACHT, LRR and PYD domains-containing protein 3 Homo sapiens (human)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.175
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)2.9256
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.308
NADPH oxidase 4Homo sapiens (human)1.13
Inositol hexakisphosphate kinase 2Homo sapiens (human)7.1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.5

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Du, H; Feng, Y; Hu, Y; Jiang, C; Li, B; Lu, S; Wu, T1
Chen, L; Deng, XR; DU, HZ; Ji, RS; Li, ZY; Liu, DH; Lu, S; Wang, ZL; Wu, T1
Cao, J; Du, H; Guo, Y; Li, B; Li, X; Lu, S; Wang, X; Wang, Y; Wang, Z; Yuan, D1

Other Studies

4 other study(ies) available for oxymatrine and apigenin

ArticleYear
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Apigenin-oxymatrine binary co-amorphous mixture: Enhanced solubility, bioavailability, and anti-inflammatory effect.
    Food chemistry, 2022, Mar-30, Volume: 373, Issue:Pt B

    Topics: Administration, Oral; Alkaloids; Anti-Inflammatory Agents; Apigenin; Biological Availability; Calorimetry, Differential Scanning; Quinolizines; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2022
[Effect of apigenin in combination with oxymatrine on non-small cell lung cancer and mechanism].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:3

    Topics: Alkaloids; Apigenin; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Molecular Docking Simulation; Quinolizines; RNA, Messenger

2023
Complexation of Apigenin and Oxymatrine Leading to Enhanced Anti-inflammatory Activity.
    Journal of natural products, 2023, 05-26, Volume: 86, Issue:5

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Apigenin; Matrines; Mice; Quinolizines; Rats

2023