oxymatrine has been researched along with aldosterone in 3 studies
| Studies (oxymatrine) | Trials (oxymatrine) | Recent Studies (post-2010) (oxymatrine) | Studies (aldosterone) | Trials (aldosterone) | Recent Studies (post-2010) (aldosterone) |
|---|---|---|---|---|---|
| 412 | 16 | 270 | 25,333 | 1,517 | 4,169 |
| Protein | Taxonomy | oxymatrine (IC50) | aldosterone (IC50) |
|---|---|---|---|
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0048 | |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | 0.043 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, CH; Shen, XC; Wang, YY; Xiao, TT; Zhang, Y | 1 |
| Chen, Y; Fu, L; Huang, H; Shen, X; Tao, L; Tu, L; Xu, Y; Zhang, Y | 1 |
| Chen, S; Gan, S; Luo, H; Shen, X; Tao, L; Xu, Y; Yang, Y | 1 |
3 other study(ies) available for oxymatrine and aldosterone
| Article | Year |
|---|---|
Similar to spironolactone, oxymatrine is protective in aldosterone-induced cardiomyocyte injury via inhibition of calpain and apoptosis-inducing factor signaling.
Topics: Aldosterone; Alkaloids; Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; BH3 Interacting Domain Death Agonist Protein; Calpain; Caspase 3; Gene Expression Regulation; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Myocytes, Cardiac; Primary Cell Culture; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction; Spironolactone | 2014 |
Oxymatrine inhibits aldosterone-induced rat cardiac fibroblast proliferation and differentiation by attenuating smad-2,-3 and-4 expression: an in vitro study.
Topics: Aldosterone; Alkaloids; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Fibroblasts; Myocardium; Protective Agents; Quinolizines; Rats; Rats, Sprague-Dawley; Smad Proteins | 2016 |
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Topics: Aldosterone; Alkaloids; Animals; Animals, Newborn; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transdifferentiation; Collagen; Fibroblasts; Fibrosis; Heart; Kelch-Like ECH-Associated Protein 1; Myocardium; Myofibroblasts; NF-E2-Related Factor 2; Quinolizines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2019 |