Compounds > oxymatrine
Page last updated: 2024-09-02

oxymatrine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

oxymatrine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 2 studies

Compound Research Comparison

Studies
(oxymatrine)		Trials
(oxymatrine)		Recent Studies (post-2010)
(oxymatrine)		Studies
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Trials
(2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)		Recent Studies (post-2010) (2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one)
410274,82351,810
412162704,82351,810

Protein Interaction Comparison

ProteinTaxonomyoxymatrine (IC50)2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one (IC50)
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)4
Chain A, Methyltransferase WbddEscherichia coli68
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)1.6413
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)1.4218
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.002
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)9.614
Cytochrome P450 1A2Homo sapiens (human)1
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)1.6
Serine/threonine-protein kinase pim-1Homo sapiens (human)3.364
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)1.6
Casein kinase II subunit alpha'Homo sapiens (human)6.9
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.1638
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.796
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.002
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformBos taurus (cattle)3.7533
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)1.4593
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Mus musculus (house mouse)0.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)1.2922
Serine/threonine-protein kinase mTORHomo sapiens (human)4.1638
Serine/threonine-protein kinase mTORRattus norvegicus (Norway rat)2.5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)2.4845
Glycogen synthase kinase-3 betaHomo sapiens (human)8.1
Serine/threonine-protein kinase PLK1Homo sapiens (human)2.05
Casein kinase II subunit betaHomo sapiens (human)6.9
Casein kinase II subunit alphaHomo sapiens (human)6.9
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)1.32
Mu-type opioid receptorCavia porcellus (domestic guinea pig)1.6
Serine/threonine-protein kinase pim-3Homo sapiens (human)1.4
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)1.72
Serine/threonine-protein kinase PLK3Homo sapiens (human)3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Chen, Q; Deng, S; Dong, Y; Duan, X; Fan, H; Liu, X; Liu, Y; Nan, Z; Shou, Z; Tang, Q; Wu, H; Xu, M; Yang, J; Zhang, L; Zuo, D1

Other Studies

2 other study(ies) available for oxymatrine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Oxymatrine protects against DSS-induced colitis via inhibiting the PI3K/AKT signaling pathway.
    International immunopharmacology, 2017, Volume: 53

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Chromones; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred BALB C; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Quinolizines; Signal Transduction; Sophora; Th1 Cells; Th17 Cells

2017