oxycodone has been researched along with quinidine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Heiskanen, T; Kalso, E; Olkkola, KT | 1 |
| Lurcott, G | 1 |
| Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD | 1 |
| Raffa, RB; Stone, DJ | 1 |
| Daali, Y; Dayer, P; Desmeules, JA; Eap, CB; Hochstrasser, D; Hopfgartner, G; Rebsamen, MC; Rossier, MF; Samer, CF; Wagner, M | 1 |
2 review(s) available for oxycodone and quinidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The effects of the genetic absence and inhibition of CYP2D6 on the metabolism of codeine and its derivatives, hydrocodone and oxycodone.
Topics: Analgesics, Opioid; Anti-Arrhythmia Agents; Binding, Competitive; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Fluoxetine; Humans; Hydrocodone; Oxycodone; Paroxetine; Quinidine; Selective Serotonin Reuptake Inhibitors | 1998 |
2 trial(s) available for oxycodone and quinidine
| Article | Year |
|---|---|
Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.
Topics: Adult; Analgesics, Opioid; Cognition; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Delayed-Action Preparations; Double-Blind Method; Enzyme Inhibitors; Humans; Oxycodone; Psychomotor Performance; Quinidine | 1998 |
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Genotype; Humans; Ketoconazole; Male; Metabolic Detoxication, Phase I; Oxycodone; Phenotype; Polymorphism, Genetic; Quinidine; Receptors, Opioid, mu; Young Adult | 2010 |
7 other study(ies) available for oxycodone and quinidine
| Article | Year |
|---|---|
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine | 2004 |
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.
Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol | 2008 |