oxycodone and oxymorphone

oxycodone has been researched along with oxymorphone in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (2.86)	18.7374
1990's	10 (9.52)	18.2507
2000's	21 (20.00)	29.6817
2010's	57 (54.29)	24.3611
2020's	14 (13.33)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Eddington, ND; Hassan, HE; Lee, IJ; Mason, CW; Myers, AL; Sinz, MW; Wang, D; Wang, H	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B	1
Kalso, E; Olkkola, KT; Pöyhiä, R; Seppälä, T	2
Bagley, JR; Baker, JK; Riley, TN; Skelton, RE	1
Chi, CJ; Guo, YM; Liu, MQ; Zhu, CL	1
Bowers, CY; Chang, D; Chang, K; Hong, A; Momany, F; Reynolds, GA	1
Dietzen, DJ; Koenig, J; Turk, J	1
Bochner, F; Cleary, J; Mikus, G; Somogyi, A	1
Benziger, DP; Burke, BE; Fitzmartin, RD; Goldenheim, PD; Kaiko, RF; Reder, RF	1
Kirvela, M; Lindgren, L; Olkkola, KT; Seppala, T	1
Kaiko, RF	1
Borsodi, A; Hosztafi, S; Nevin, ST; Rónai, AZ; Spetea, M; Tóth, G	1
Rueter, S; Stoll, AL	1
Bohrer, A; Koenig, J; Nowatzke, W; Saunders, A; Turk, J; Zeng, J	1
Davis, M; Reder, RF; Stambaugh, H; Stambaugh, JE; Stambaugh, MD	1
Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD	1
DeCicco, L; Kemp, P; Kupiec, T; McCutcheon, JR; Spiehler, VR	1
Ahdieh, H; Dvergsten, C; Gabrail, NY	1
Boström, E; Hammarlund-Udenaes, M; Jansson, B; Simonsson, US	1
Ahdieh, H; Gimbel, J	1
Dvergsten, C; Gimbel, J; Hale, ME	1
Cooper, RM; Lee, MA; Leng, ME	1
Backer, RC; Monforte, JR; Poklis, A	1
Kokki, H; Lasalmi, M; Lehtola, S; Ojanperä, I; Ranta, VP; Rasanen, I; Vanamo, K	1
Kalso, EA; Kontinen, VK; Korpi, ER; Lemberg, KK; Siiskonen, AO; Viljakka, KM; Yli-Kauhaluoma, JT	1
Edwards, SR; Smith, MT	1
D'Arcy, Y	1
Chan, S; Edwards, SR; Smith, MT; Wyse, BD	1
Jamerson, MH; Kazarian, CM; Klette, KL; McKinley, S; Snyder, JJ; Welsh, E	1
Benyamin, R; Glaser, SE; Hansen, H; Manchikanti, L; Patel, S; Trescot, AM	1
Neuvonen, M; Neuvonen, PJ	1
Arttamangkul, S; Low, MJ; Pintar, J; Quillinan, N; von Zastrow, M; Williams, JT	1
Brosen, K; Enggaard, TP; Mikkelsen, S; Nielsen, F; Noehr-Jensen, L; Pedersen, RS; Sindrup, SH; Zwisler, ST	1
Brosen, K; Enggaard, TP; Mikkelsen, S; Sindrup, SH; Zwisler, ST	1
Black, DL; Caplan, YH; Cawthon, B; Cone, EJ; Heltsley, R; Moser, F; Robert, T; Zichterman, A	1
Grönlund, J; Hagelberg, NM; Laine, K; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Saari, TI	1
Dahn, T; Gunn, J; Kriger, S; Terrell, AR	1
Bourgogne, E; Hopfgartner, G; Varesio, E; Wagner, M	1
Gingras, M; Laberge, MH; Lefebvre, M	1
Moore, C; Vincent, M	1
Gould, EM; Peniston, JH; Xiang, Q	1
Daali, Y; Dayer, P; Desmeules, JA; Eap, CB; Hochstrasser, D; Hopfgartner, G; Rebsamen, MC; Rossier, MF; Samer, CF; Wagner, M	1
Drewe, J; Hammann, F; Krähenbühl, S; Kummer, O; Moser, C; Schaller, O	1
Andreassen, TN; Bjordal, K; Dale, O; Davies, A; Kaasa, S; Klepstad, P; Lundström, S	1
Aantaa, R; Kuusniemi, K; Liukas, A; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Virolainen, P	1
Kagawa, Y; Kawakami, J; Naito, T; Ohnishi, K; Takashina, Y; Tashiro, M; Yamamoto, K	1
Alford, I; Shan, X; Tiscione, NB; Yeatman, DT	1
Ben-Joseph, RH; Fu, C; Ohsfeldt, RL; Puenpatom, A; Rubino, M; Summers, KH	1
Andreassen, TN; Bjordal, K; Dale, O; Davies, A; Eftedal, I; Kaasa, S; Klepstad, P; Lundström, S	1
Ben-Joseph, RH; Berner, T; Birnbaum, HG; Kirson, NY; Peterson, K; Schiller, M; Summers, KH; Waldman, T; White, AG	1
French, D; Lynch, K; Wu, A	1
Atayee, RS; Best, BM; Pesce, AJ; Yee, DA	1
Pappagallo, M; Sokolowska, M	1
Björkman, S; Boström, E; Hammarlund-Udenaes, M; Keizer, R; Sadiq, MW	1
El Fallah, S; Klimas, R; Mikus, G; Witticke, D	1
Book, M; Lehmann, LE; Musshoff, F; Stamer, UM; Stuber, F; Zhang, L	1
Black, DL; Cone, EJ; Flegel, RR; Heltsley, R; Lodico, CP; Mitchell, JM	1
Ishida, T; Kawakami, J; Naito, T; Ohnishi, K; Tashiro, M	1
Black, RA; Butler, SF; Cassidy, TA; DasMahapatra, P; Wieman, MS	1
Atayee, RS; Best, BM; Elder, NM; Ma, JD	2
Ben-Joseph, R; Birnbaum, HG; Kirson, NY; Michna, E; Shei, A	1
Dong, RH; Gao, HZ; Hao, GT; Li, YY; Liang, YG; Liu, ZY; Qu, HY; Wang, XF; Zhang, LJ; Zhou, HY	1
Black, DL; DePriest, AZ; Heltsley, R; Puet, BL; Robert, T	1
Chayahara, N; Fujiwara, Y; Imamura, Y; Kiyota, N; Minami, H; Mukohara, T; Shimada, T; Toyoda, M	1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M	1
Shan, X; Tiscione, NB; Yeatman, DT	1
Bernardy, K; Häuser, W; Maier, C	1
Gangahar, D	1
Gaudette, F; Michaud, V; Sirhan-Daneau, A; St-Onge, M; Turgeon, J	1
Knothe, C; Lötsch, J; Walter, C	1
ElSohly, MA; Godfrey, M; Gul, SW; Gul, W; Stamper, B	1
Cicero, TJ; Ellis, MS; Kasper, ZA	1
Black, DL; Cone, EJ; DePriest, AZ; Flegel, R; Heltsley, R; LoDico, C; Mitchell, JM	1
Gurwitz, JH; Hume, AL; Lapane, KL; Pimentel, CB; Tjia, J	1
Cavallari, G; Croci Chiocchini, AL; Di Nino, G; Donati, G; Gori, A; La Manna, G; Mandrioli, R; Melotti, RM; Mercolini, L; Protti, M; Samolsky Dekel, BG; Vasarri, A	1
Darragh, A; Lee, LA; Marinova, M; Mastrianni, KR; Melendez, C; Ryan, E; Sitasuwan, P	1
Dasgupta, A; Dixon, RB	1
Brauneis, S; Busardò, FP; Forneris, A; Kyriakou, C; Marinelli, E; Pacifici, R; Pantano, F; Pichini, S	1
Clucas, D; Filshie, R; Nandurkar, H; Robson, KJ	1
Catapano, MC; Gerra, G; Mandrioli, R; Mercolini, L; Protti, M; Rudge, J; Samolsky Dekel, BG; Somaini, L	1
Bynum, ND; Flegel, R; Grabenauer, M; Hayes, ED; Mitchell, JM; Moore, KN; White, RM	1
Bau, GE; Dart, RC; Dasgupta, N; Lebin, JA; Murphy, DL; Severtson, SG	1
Amico, P; Dickenmann, M; Duthaler, U; Hammann, F; Haschke, M; Jehle, AW; Kalbermatter, S; Krähenbühl, S; Lenherr, C; Leuppi-Taegtmeyer, A; Liechti, ME; Meyer Zu Schwabedissen, HE; Schmid, Y	1
Guevara, M; Hofilena, D; Mikel, C; West, R	1
Hautajärvi, H; Kinnunen, M; Kokki, H; Kokki, M; Lantto, J; Räsänen, J; Voipio, HM	1
Cashman, JR; de Kater, A; Gohdes, M; Schoenhard, G	1
Dani, M; Kennedy, D	1
Coyle, DT; Haynes, K; Maro, JC; Meyer, T; Moeny, D; Staffa, J; Toh, S; Welch, EC; Woods, C; Woodworth, TS	1
Alhaj-Suliman, SO; Milavetz, G; Salem, AK	1
Black, JC; Dart, RC; Margolin, ZR; Olson, RA	1
Chermà, MD; Gréen, H; Jakobsson, G; Kronstrand, R; Swortwood, MJ; Truver, MT	1
Al-Qurain, AA; Mackenzie, L; Roberts, MS; Wiese, MD; Williams, DB	1
Babalonis, S; Comer, SD; Hatton, KW; Jones, JD; Lofwall, MR; Manubay, J; Nuzzo, P; Walsh, SL; Whittington, RA	1
Bazgier, V; Čechová, P; El Balkhi, S; Javellaud, J; Lawson, R; Marquet, P; Otyepka, M; Picard, N; Saint-Marcoux, F; Trouillas, P; Zarrouk, E	1
Arguelles, N; El-Sherbeni, AA; Miksys, S; Richards, J; Tyndale, RF	1
Coulter, C; Garnier, M; Moore, C	1
Cassella-Mclane, G; Choucair, I; Durant, TJS; El-Khoury, JM; Vera, MA; Villalba, CF	1
Black, J; Dart, R; Ellis, M; Iwanicki, J; Jewell, J; Olsen, H	1
Benoist, GE; Cremers, RGHM; Detert Oude Weme, SEH; Hulskotte, LMG; Imholz, ALT; Jansman, FGA; Reyners, AKL; Taxis, K; van Berlo-van de Laar, IRF; Vervenne, WL	1

Reviews

6 review(s) available for oxycodone and oxymorphone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effectiveness of opioids in the treatment of chronic non-cancer pain. Pain physician, 2008, Volume: 11, Issue:2 Suppl Topics: Analgesics, Opioid; Drug Administration Schedule; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Oxymorphone; Pain; Quality of Life; Time Factors; Tramadol	2008
[Long-term opioid therapy in chronic noncancer pain. A systematic review and meta-analysis of efficacy, tolerability and safety in open-label extension trials with study duration of at least 26 weeks]. Schmerz (Berlin, Germany), 2015, Volume: 29, Issue:1 Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Hydromorphone; Long-Term Care; Morphine; Oxycodone; Oxymorphone; Pain Measurement; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Tramadol; Treatment Outcome	2015
Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations. Clinical pharmacokinetics, 2016, Volume: 55, Issue:7 Topics: Analgesics, Opioid; Buprenorphine; Chemistry, Pharmaceutical; Humans; Morphine; Oxycodone; Oxymorphone; Pain	2016
Model-based Meta-analysis to Compare Primary Efficacy-endpoint, Efficacy-time Course, Safety, and Tolerability of Opioids Used in the Management of Osteoarthritic Pain in Humans. Current drug metabolism, 2020, Volume: 21, Issue:5 Topics: Analgesics, Opioid; Humans; Models, Biological; Osteoarthritis; Oxycodone; Oxymorphone; Pain; Randomized Controlled Trials as Topic; Tramadol; Treatment Outcome	2020

Trials

18 trial(s) available for oxycodone and oxymorphone

Article	Year
The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects. British journal of clinical pharmacology, 1992, Volume: 33, Issue:6 Topics: Administration, Oral; Adult; Amitriptyline; Chromatography, Gas; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Morphinans; Oxycodone; Oxymorphone; Placebos; Reference Values	1992
The pharmacokinetics of oxycodone in uremic patients undergoing renal transplantation. Journal of clinical anesthesia, 1996, Volume: 8, Issue:1 Topics: Adult; Analgesics, Opioid; Biotransformation; Female; Half-Life; Humans; Injections, Intravenous; Kidney Transplantation; Male; Morphinans; Oxycodone; Oxymorphone; Uremia	1996
Pharmacokinetics and pharmacodynamics of controlled-release opioids. Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:1 Pt 2 Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxycodone; Oxymorphone	1997
Double-blind, randomized comparison of the analgesic and pharmacokinetic profiles of controlled- and immediate-release oral oxycodone in cancer pain patients. Journal of clinical pharmacology, 2001, Volume: 41, Issue:5 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biological Availability; Chronic Disease; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain; Pain Measurement; Therapeutic Equivalency; Vomiting	2001
Establishing the dosage equivalency of oxymorphone extended release and oxycodone controlled release in patients with cancer pain: a randomized controlled study. Current medical research and opinion, 2004, Volume: 20, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasms; Oxycodone; Oxymorphone; Pain; United States	2004
The efficacy and safety of oral immediate-release oxymorphone for postsurgical pain. Anesthesia and analgesia, 2004, Volume: 99, Issue:5 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Mental Recall; Middle Aged; Oxycodone; Oxymorphone; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting	2004
Efficacy and safety of oxymorphone extended release in chronic low back pain: results of a randomized, double-blind, placebo- and active-controlled phase III study. The journal of pain, 2005, Volume: 6, Issue:1 Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Chronic Disease; Constipation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Low Back Pain; Male; Middle Aged; Oxycodone; Oxymorphone; Pain Measurement; Placebo Effect; Placebos; Sleep Stages; Treatment Outcome	2005
Comparison of oxycodone pharmacokinetics after buccal and sublingual administration in children. Clinical pharmacokinetics, 2006, Volume: 45, Issue:7 Topics: Administration, Buccal; Administration, Sublingual; Analgesics, Opioid; Area Under Curve; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Indicators and Reagents; Infant; Male; Morphinans; Oxycodone; Oxymorphone	2006
The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism. Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:4 Topics: Adult; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2D6; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Oxycodone; Oxymorphone; Pain; Pain Measurement; Pain Threshold; Polymorphism, Genetic; Young Adult	2009
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety. British journal of pharmacology, 2010, Volume: 160, Issue:4 Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Genotype; Humans; Male; Metabolic Detoxication, Phase I; Middle Aged; Oxycodone; Oxymorphone; Pain Threshold; Phenotype; Polymorphism, Genetic; Psychomotor Performance; Reflex, Pupillary; Young Adult	2010
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European journal of clinical pharmacology, 2011, Volume: 67, Issue:1 Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Genotype; Humans; Ketoconazole; Miosis; Morphinans; Oxycodone; Oxymorphone; Pain Measurement; Paroxetine; Placebos; Young Adult	2011
Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients. European journal of clinical pharmacology, 2011, Volume: 67, Issue:5 Topics: Analgesics, Opioid; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Linear Models; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain; Sex Factors	2011
Elimination of intravenous oxycodone in the elderly: a pharmacokinetic study in postoperative orthopaedic patients of different age groups. Drugs & aging, 2011, Jan-01, Volume: 28, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Area Under Curve; Chromatography, Liquid; Creatinine; Cytochrome P-450 CYP2D6; Female; Genotype; Glomerular Filtration Rate; Humans; Injections, Intravenous; Male; Middle Aged; Morphinans; Orthopedic Procedures; Oxycodone; Oxymorphone; Pain, Postoperative; Tandem Mass Spectrometry; Tissue Distribution; Young Adult	2011
CYP3A53 affects plasma disposition of noroxycodone and dose escalation in cancer patients receiving oxycodone. Journal of clinical pharmacology, 2011, Volume: 51, Issue:11* Topics: Aged; Asian People; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Polymorphism, Genetic; Receptors, Opioid, mu	2011
Cancer cachexia raises the plasma concentration of oxymorphone through the reduction of CYP3A but not CYP2D6 in oxycodone-treated patients. Journal of clinical pharmacology, 2013, Volume: 53, Issue:8 Topics: Aged; Analgesics, Opioid; Cachexia; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain	2013
Effects of aprepitant on the pharmacokinetics of controlled-release oral oxycodone in cancer patients. PloS one, 2014, Volume: 9, Issue:8 Topics: Adult; Aged; Analgesics, Opioid; Aprepitant; Area Under Curve; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphinans; Morpholines; Neoplasms; Oxycodone; Oxymorphone; Pain	2014
Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019, 04-01, Volume: 34, Issue:4 Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Female; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Morphinans; Naloxone; Narcotic Antagonists; Oxycodone; Oxymorphone; Prognosis; Renal Dialysis; Tissue Distribution	2019
Relative potency of intravenous oxymorphone compared to other µ opioid agonists in humans - pilot study outcomes. Psychopharmacology, 2021, Volume: 238, Issue:9 Topics: Analgesics, Opioid; Humans; Opioid-Related Disorders; Oxycodone; Oxymorphone; Pilot Projects	2021

Other Studies

81 other study(ies) available for oxycodone and oxymorphone

Article	Year
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Induction of xenobiotic receptors, transporters, and drug metabolizing enzymes by oxycodone. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Animals; Cell Line, Tumor; Gene Expression; Humans; Liver; Male; Oxycodone; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Drug; Transcriptional Activation; Xenobiotics	2013
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1. Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21 Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation	2019
The pharmacokinetics of oxycodone after intravenous injection in adults. British journal of clinical pharmacology, 1991, Volume: 32, Issue:4 Topics: Adult; Female; Humans; Injections, Intravenous; Male; Oxycodone; Oxymorphone	1991
Estimation of high pressure liquid chromatographic retention indices of narcotic analgetics and related drugs. Journal of chromatographic science, 1980, Volume: 18, Issue:4 Topics: Analgesics, Opioid; Butanones; Chromatography, High Pressure Liquid; Fentanyl; Ketones; Naloxone; Octanols; Oxycodone; Oxymorphone; Water	1980
[Synthesis of long-acting analgesic hydrazone derivatives of 14-hydroxycodeinone and 14-hydroxymorphine]. Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:6 Topics: Analgesics; Animals; Codeine; Hydromorphone; Mice; Oxycodone; Oxymorphone	1983
Structure-activity relationships of a synthetic pentapeptide that specifically releases growth hormone in vitro. Endocrinology, 1980, Volume: 106, Issue:3 Topics: Amino Acid Sequence; Animals; Female; Growth Hormone; In Vitro Techniques; Naloxone; Oligopeptides; Oxycodone; Oxymorphone; Pituitary Gland; Rats; Structure-Activity Relationship	1980
Facilitation of thin-layer chromatographic identification of opiates by derivatization with acetic anhydride or methoxyamine. Journal of analytical toxicology, 1995, Volume: 19, Issue:5 Topics: Acetic Anhydrides; Chromatography, Thin Layer; Codeine; Humans; Hydrocodone; Hydromorphone; Hydroxylamines; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone	1995
The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3 Topics: Analgesia; Animals; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Mixed Function Oxygenases; Morphine; Oxycodone; Oxymorphone; Quinine; Rats; Rats, Sprague-Dawley	1994
Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone. Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:1 Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Reference Values	1996
Affinity profiles of novel delta-receptor selective benzofuran derivatives of non-peptide opioids. Neurochemical research, 1998, Volume: 23, Issue:9 Topics: Animals; Benzeneacetamides; Benzofurans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Naltrexone; Oligopeptides; Oxycodone; Oxymorphone; Pyrrolidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium	1998
Treatment augmentation with opiates in severe and refractory major depression. The American journal of psychiatry, 1999, Volume: 156, Issue:12 Topics: Comorbidity; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Narcotics; Opioid-Related Disorders; Oxycodone; Oxymorphone; Treatment Outcome	1999
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis, 1999, Volume: 20, Issue:5 Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone	1999
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine	2004
Screening postmortem whole blood for oxycodone by ELISA response ratios. Journal of forensic sciences, 2004, Volume: 49, Issue:3 Topics: Analgesics, Opioid; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Oxycodone; Oxymorphone; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity; Substance Abuse Detection	2004
The use of liquid chromatography/mass spectrometry for quantitative analysis of oxycodone, oxymorphone and noroxycodone in Ringer solution, rat plasma and rat brain tissue. Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:21 Topics: Analgesics, Opioid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Injections, Intravenous; Isotonic Solutions; Morphinans; Oxycodone; Oxymorphone; Rats; Reproducibility of Results; Ringer's Solution; Spectrometry, Mass, Electrospray Ionization	2004
Measurements of plasma oxycodone, noroxycodone and oxymorphone levels in a patient with bilateral nephrectomy who is undergoing haemodialysis. Palliative medicine, 2005, Volume: 19, Issue:3 Topics: Analgesics, Opioid; Female; Humans; Kidney Failure, Chronic; Middle Aged; Morphinans; Nephrectomy; Oxycodone; Oxymorphone; Renal Dialysis	2005
Evaluation of the DRI oxycodone immunoassay for the detection of oxycodone in urine. Journal of analytical toxicology, 2005, Volume: 29, Issue:7 Topics: Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Narcotics; Oxycodone; Oxymorphone; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection	2005
Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats. Anesthesiology, 2006, Volume: 105, Issue:4 Topics: Algorithms; Analgesics, Opioid; Animals; Area Under Curve; Autoradiography; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intravenous; Injections, Spinal; Male; Morphinans; Morphine; Motor Activity; Oxycodone; Oxymorphone; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction	2006
Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Apr-01, Volume: 848, Issue:2 Topics: Analgesics, Opioid; Animals; Calibration; Chromatography, High Pressure Liquid; Injections, Intravenous; Male; Molecular Structure; Morphinans; Oxycodone; Oxymorphone; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors	2007
New pain management options: drugs. Nursing, 2007, Volume: 37, Issue:1 Topics: Analgesics, Opioid; Cannabidiol; Cannabinoids; Carbazoles; Chronic Disease; Dronabinol; Drug Combinations; Humans; Ibuprofen; Oxycodone; Oxymorphone; Pain; Plant Extracts; Serotonin Receptor Agonists; Tryptamines	2007
Sex differences in the pharmacokinetics, oxidative metabolism and oral bioavailability of oxycodone in the Sprague-Dawley rat. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:3 Topics: Administration, Oral; Analgesics, Opioid; Animals; Biological Availability; Female; Male; Morphinans; Oxidation-Reduction; Oxycodone; Oxymorphone; Rats; Rats, Sprague-Dawley; Sex Characteristics	2008
Rapid quantification of urinary oxycodone and oxymorphone using fast gas chromatography-mass spectrometry. Journal of analytical toxicology, 2007, Volume: 31, Issue:8 Topics: Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Oxycodone; Oxymorphone; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry	2007
Determination of oxycodone, noroxycodone, oxymorphone, and noroxymorphone in human plasma by liquid chromatography-electrospray-tandem mass spectrometry. Therapeutic drug monitoring, 2008, Volume: 30, Issue:3 Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Morphinans; Oxycodone; Oxymorphone; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet	2008
Differential activation and trafficking of micro-opioid receptors in brain slices. Molecular pharmacology, 2008, Volume: 74, Issue:4 Topics: Analgesics, Opioid; Animals; Brain; Chelating Agents; Egtazic Acid; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fluorescent Antibody Technique, Direct; Locus Coeruleus; Methadone; Mice; Mice, Knockout; Mice, Transgenic; Morphine; Neurons; Oxycodone; Oxymorphone; Protein Transport; Radioligand Assay; Receptors, Opioid, mu; Recombinant Fusion Proteins; Time Factors	2008
Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:2 Topics: Adolescent; Adult; Aged; Alleles; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Antiemetics; Consciousness; Cytochrome P-450 CYP2D6; Double-Blind Method; Female; Gene Frequency; Genotype; Humans; Injections, Intravenous; Intraoperative Care; Male; Middle Aged; Morphine; Neuromuscular Blocking Agents; Oxycodone; Oxymorphone; Pain Measurement; Pain, Postoperative; Polymorphism, Single Nucleotide; Young Adult	2010
Urine testing for norcodeine, norhydrocodone, and noroxycodone facilitates interpretation and reduces false negatives. Forensic science international, 2010, May-20, Volume: 198, Issue:1-3 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; False Negative Reactions; Forensic Toxicology; Humans; Hydrocodone; Medication Adherence; Morphinans; Oxycodone; Oxymorphone; Pain; Tandem Mass Spectrometry	2010
Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone. European journal of clinical pharmacology, 2010, Volume: 66, Issue:4 Topics: Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Humans; Injections, Intravenous; Itraconazole; Morphinans; Oxidation-Reduction; Oxycodone; Oxymorphone	2010
Quantitation of morphine, codeine, hydrocodone, hydromorphone, oxycodone, oxymorphone, and 6-monoacetylmorphine (6-MAM) in urine, blood, serum, or plasma using liquid chromatography with tandem mass spectrometry detection. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603 Topics: Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry	2010
Quantitation of polar analytes using column-switching: application to oxycodone and three metabolites in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-01, Volume: 878, Issue:7-8 Topics: Chromatography, Liquid; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Morphinans; Oxycodone; Oxymorphone; Perchlorates; Reproducibility of Results; Sensitivity and Specificity	2010
Evaluation of the usefulness of an oxycodone immunoassay in combination with a traditional opiate immunoassay for the screening of opiates in urine. Journal of analytical toxicology, 2010, Volume: 34, Issue:2 Topics: Acetylation; Codeine; False Negative Reactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrocodone; Hydromorphone; Immunoassay; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection	2010
Improved oxymorphone detection in postmortem specimens. Journal of analytical toxicology, 2010, Volume: 34, Issue:2 Topics: Analgesics, Opioid; Cross Reactions; Diagnosis; Drug Overdose; Enzyme-Linked Immunosorbent Assay; Humans; Opioid-Related Disorders; Oxycodone; Oxymorphone; Substance Abuse Detection	2010
Factors affecting acceptability of titrated oxymorphone extended release in chronic low back pain - an individual patient analysis. Current medical research and opinion, 2010, Volume: 26, Issue:8 Topics: Aged; Analgesics, Opioid; Chronic Disease; Clinical Trials, Phase III as Topic; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans; Hydromorphone; Low Back Pain; Male; Middle Aged; Oxycodone; Oxymorphone; Pain Measurement; Patient Acceptance of Health Care; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Treatment Outcome	2010
Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry. Journal of analytical toxicology, 2011, Volume: 35, Issue:2 Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection	2011
A comparison of daily average consumption (DACON) of oxycodone and oxymorphone long-acting oral tablets. Journal of managed care pharmacy : JMCP, 2011, Volume: 17, Issue:5 Topics: Administration, Oral; Analgesics, Opioid; Chi-Square Distribution; Chronic Disease; Cost Savings; Delayed-Action Preparations; Drug Costs; Drug Prescriptions; Drug Utilization Review; Female; Humans; Insurance, Pharmaceutical Services; Linear Models; Male; Managed Care Programs; Middle Aged; Multivariate Analysis; Oxycodone; Oxymorphone; Pain; Practice Patterns, Physicians'; Retrospective Studies; Tablets; Time Factors; United States	2011
Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study. European journal of clinical pharmacology, 2012, Volume: 68, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biotransformation; Chronic Pain; Cohort Studies; Cross-Sectional Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Monitoring; Europe; Female; Genetic Association Studies; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Polymorphism, Genetic; Severity of Illness Index	2012
Direct and indirect costs of patients treated with extended-release oxymorphone HCl or controlled-release oxycodone HCl. Journal of medical economics, 2012, Volume: 15, Issue:1 Topics: Adolescent; Adult; Analgesics, Opioid; Databases, Factual; Delayed-Action Preparations; Female; Health Expenditures; Humans; Insurance Claim Review; Male; Middle Aged; Oxycodone; Oxymorphone; Young Adult	2012
Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites. Bioanalysis, 2011, Volume: 3, Issue:23 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Gas Chromatography-Mass Spectrometry; Glucuronides; Humans; Hydrocodone; Hydromorphone; Hydrophobic and Hydrophilic Interactions; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry	2011
Observations on the urine metabolic ratio of oxymorphone to oxycodone in pain patients. Journal of analytical toxicology, 2012, Volume: 36, Issue:4 Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Humans; Models, Biological; Oxycodone; Oxymorphone; Pain; Reference Values; Reproducibility of Results; Retrospective Studies; Tandem Mass Spectrometry; Time Factors	2012
The implications of tamper-resistant formulations for opioid rotation. Postgraduate medicine, 2012, Volume: 124, Issue:5 Topics: Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Drug Combinations; Drug Compounding; Drug Tolerance; Humans; Morphine; Naltrexone; Opioid-Related Disorders; Oxycodone; Oxymorphone; Patient Selection	2012
Oxymorphone active uptake at the blood-brain barrier and population modeling of its pharmacokinetic-pharmacodynamic relationship. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:9 Topics: Analgesics, Opioid; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Male; Models, Biological; Oxycodone; Oxymorphone; Rats; Rats, Sprague-Dawley	2013
Contribution of oxycodone and its metabolites to the overall analgesic effect after oxycodone administration. Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:5 Topics: Analgesia; Analgesics, Opioid; Blood-Brain Barrier; Brain; Cytochrome P-450 CYP2D6; Drug Interactions; Genotype; Humans; Morphinans; Oxycodone; Oxymorphone; Polymorphism, Genetic; Receptors, Opioid	2013
CYP2D6 genotype dependent oxycodone metabolism in postoperative patients. PloS one, 2013, Volume: 8, Issue:3 Topics: Aged; Analgesics, Opioid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Genotype; Humans; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Spectrometry, Mass, Electrospray Ionization	2013
Prescription opioids. I. Metabolism and excretion patterns of oxycodone in urine following controlled single dose administration. Journal of analytical toxicology, 2013, Volume: 37, Issue:5 Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Employment; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Time Factors; Workplace; Young Adult	2013
Changes in prevalence of prescription opioid abuse after introduction of an abuse-deterrent opioid formulation. Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:3 Topics: Adolescent; Adult; Analgesics, Opioid; Cross-Sectional Studies; Female; Humans; Male; Opioid-Related Disorders; Oxycodone; Oxymorphone; Prevalence; Young Adult	2014
Observations of urinary oxycodone and metabolite distributions in pain patients. Journal of analytical toxicology, 2014, Volume: 38, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Analgesics, Opioid; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Pain; Retrospective Studies; Sex Factors; Specimen Handling; Tandem Mass Spectrometry; Young Adult	2014
Use of prescription opioids with abuse-deterrent technology to address opioid abuse. Current medical research and opinion, 2014, Volume: 30, Issue:8 Topics: Adolescent; Adult; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Opioid-Related Disorders; Oxycodone; Oxymorphone; Patient Acceptance of Health Care; United States; Young Adult	2014
Pharmacokinetics of oxycodone hydrochloride and three of its metabolites after intravenous administration in Chinese patients with pain. Pharmacological reports : PR, 2014, Volume: 66, Issue:1 Topics: Adult; Analgesics, Opioid; Area Under Curve; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Pain	2014
Uncertainty in assessing impact of drug-drug interactions on oxycodone metabolite patterns. Journal of analytical toxicology, 2014, Volume: 38, Issue:7 Topics: Analgesics, Opioid; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Pain	2014
Authors' reply. Journal of analytical toxicology, 2014, Volume: 38, Issue:7 Topics: Analgesics, Opioid; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Pain	2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology. Journal of analytical toxicology, 2014, Volume: 38, Issue:8 Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry	2014
Case management in a DUI lab: effect on drugs reported. Journal of analytical toxicology, 2014, Volume: 38, Issue:8 Topics: Automobile Driving; Barbiturates; Benzodiazepines; Carisoprodol; Cocaine; Dronabinol; Ethanol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Oxycodone; Oxymorphone; Substance Abuse Detection	2014
A case of rhabdomyolysis associated with severe opioid withdrawal. The American journal on addictions, 2015, Volume: 24, Issue:5 Topics: Acute Kidney Injury; Administration, Intranasal; Administration, Oral; Administration, Sublingual; Analgesics, Opioid; Buprenorphine, Naloxone Drug Combination; Follow-Up Studies; Heroin; Heroin Dependence; Humans; Intensive Care Units; Male; Opioid-Related Disorders; Oxycodone; Oxymorphone; Prescription Drugs; Rhabdomyolysis; Self Medication; Substance Withdrawal Syndrome; Young Adult	2015
Development of a sensitive method for the determination of oxycodone and its major metabolites noroxycodone and oxymorphone in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Jan-01, Volume: 1008 Topics: Chromatography, Liquid; Humans; Limit of Detection; Morphinans; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry	2016
LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II. Journal of analytical toxicology, 2016, Volume: 40, Issue:5 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Football; Humans; Hydrocodone; Hydromorphone; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical	2016
A tale of 2 ADFs: differences in the effectiveness of abuse-deterrent formulations of oxymorphone and oxycodone extended-release drugs. Pain, 2016, Volume: 157, Issue:6 Topics: Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Compounding; Female; Humans; Male; Opioid-Related Disorders; Oxycodone; Oxymorphone; Pain; Treatment Outcome	2016
Prescription Opioids. V. Metabolism and Excretion of Oxymorphone in Urine Following Controlled Single Dose Administration. Journal of analytical toxicology, 2016, Volume: 40, Issue:8 Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Creatinine; Delayed-Action Preparations; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Young Adult	2016
New Initiation of Long-Acting Opioids in Long-Stay Nursing Home Residents. Journal of the American Geriatrics Society, 2016, Volume: 64, Issue:9 Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chronic Pain; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Utilization; Female; Fentanyl; Homes for the Aged; Humans; Long-Term Care; Male; Morphine; Nursing Homes; Oxycodone; Oxymorphone; Practice Patterns, Physicians'; Rhode Island; Tramadol	2016
Dialyzability of Oxycodone and Its Metabolites in Chronic Noncancer Pain Patients with End-Stage Renal Disease. Pain practice : the official journal of World Institute of Pain, 2017, Volume: 17, Issue:5 Topics: Adult; Analgesics, Opioid; Chronic Disease; Chronic Pain; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Renal Dialysis	2017
Degradation of Opioids and Opiates During Acid Hydrolysis Leads to Reduced Recovery Compared to Enzymatic Hydrolysis. Journal of analytical toxicology, 2016, Volume: 40, Issue:8 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Glucuronidase; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Morphine; Morphine Derivatives; Opiate Alkaloids; Oxycodone; Oxymorphone; Specimen Handling; Tandem Mass Spectrometry	2016
Suitability of the DRI Hydrocodone/Hydromorphone Immunoassay in the Clinical Environment at a Lower Cutoff: Validation With LC-MS/MS Analysis. Therapeutic drug monitoring, 2016, Volume: 38, Issue:6 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Immunoassay; Oxycodone; Oxymorphone; Sensitivity and Specificity; Substance Abuse Detection; Tandem Mass Spectrometry	2016
Determination of oxycodone and its major metabolites noroxycodone and oxymorphone by ultra-high-performance liquid chromatography tandem mass spectrometry in plasma and urine: application to real cases. Clinical chemistry and laboratory medicine, 2017, Aug-28, Volume: 55, Issue:9 Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Tandem Mass Spectrometry	2017
Thrombotic microangiopathy associated with intravenous injection of extended-release oxycodone. BMJ case reports, 2017, Jul-17, Volume: 2017 Topics: Adult; Analgesics, Opioid; Antibodies, Monoclonal, Humanized; Complement Inactivating Agents; Delayed-Action Preparations; Humans; Injections, Intravenous; Male; Opioid-Related Disorders; Oxycodone; Oxymorphone; Renal Insufficiency; Substance Abuse, Intravenous; Thrombotic Microangiopathies	2017
Determination of oxycodone and its major metabolites in haematic and urinary matrices: Comparison of traditional and miniaturised sampling approaches. Journal of pharmaceutical and biomedical analysis, 2018, Apr-15, Volume: 152 Topics: Blood Specimen Collection; Body Fluids; Chromatography, Liquid; Doping in Sports; Dried Blood Spot Testing; Drug Monitoring; Humans; Miniaturization; Morphinans; Oxycodone; Oxymorphone; Plasma; Specimen Handling; Tandem Mass Spectrometry; Urine	2018
Development of a Quantitative LC-MS-MS Assay for Codeine, Morphine, 6-Acetylmorphine, Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone in Neat Oral Fluid. Journal of analytical toxicology, 2018, Jul-01, Volume: 42, Issue:6 Topics: Analgesics, Opioid; Calibration; Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Opioid-Related Disorders; Oxycodone; Oxymorphone; Predictive Value of Tests; Reference Standards; Reproducibility of Results; Saliva; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry	2018
Scoring the best deal: Quantity discounts and street price variation of diverted oxycodone and oxymorphone. Pharmacoepidemiology and drug safety, 2019, Volume: 28, Issue:1 Topics: Commerce; Cross-Sectional Studies; Drug Overdose; Humans; Illicit Drugs; Narcotics; Opioid-Related Disorders; Oxycodone; Oxymorphone; Prescription Drug Diversion; Prospective Studies; United States	2019
Positivity rates of drugs in patients treated for opioid dependence with buprenorphine: A comparison of oral fluid and urine using paired collections and LC-MS/MS. Drug and alcohol dependence, 2018, 12-01, Volume: 193 Topics: Buprenorphine; Cannabinoids; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Illicit Drugs; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Oxymorphone; Retrospective Studies; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry	2018
Oxycodone concentrations in the central nervous system and cerebrospinal fluid after epidural administration to the pregnant ewe. Basic & clinical pharmacology & toxicology, 2019, Volume: 125, Issue:5 Topics: Analgesia; Analgesics, Opioid; Animals; Brain Chemistry; Cerebellum; Cerebral Cortex; Female; Injections, Epidural; Models, Animal; Oxycodone; Oxymorphone; Pregnancy; Sheep; Spinal Cord; Thalamus; Tissue Distribution	2019
Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:2 Topics: Analgesics, Opioid; Animals; Cytochrome P-450 Enzyme System; Female; Hemoglobins; Humans; Male; Mixed Function Oxygenases; Morphinans; NADP; Oxides; Oxycodone; Oxymorphone; Rats	2020
Comparative Analysis of ELISA Immunoassay and LC-QTOF for Opiate Screening. Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4 Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection	2020
Concomitant Filled Prescriptions of Oxymorphone or Oxycodone with CYP3A Inhibitors and Inducers. Journal of managed care & specialty pharmacy, 2020, Volume: 26, Issue:5 Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Oxycodone; Oxymorphone; Pain, Intractable; Practice Patterns, Physicians'; United States	2020
Online Conversation Monitoring to Understand the Opioid Epidemic: Epidemiological Surveillance Study. JMIR public health and surveillance, 2020, 06-29, Volume: 6, Issue:2 Topics: Adult; Analgesics, Opioid; Epidemiology; Female; Fentanyl; Humans; Hydrocodone; Male; Middle Aged; Odds Ratio; Opioid Epidemic; Oxycodone; Oxymorphone; Population Surveillance; Social Media; Substance-Related Disorders; United States	2020
The Quantification of Oxycodone and Its Phase I and II Metabolites in Urine. Journal of analytical toxicology, 2022, Feb-14, Volume: 46, Issue:1 Topics: Chromatography, Liquid; Humans; Oxycodone; Oxymorphone; Pilot Projects; Tandem Mass Spectrometry	2022
Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetr Journal of pharmaceutical and biomedical analysis, 2021, Sep-05, Volume: 203 Topics: Aged; Chromatography, Liquid; Fentanyl; Humans; Morphinans; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry; Tramadol	2021
Metabolic interactions of benzodiazepines with oxycodone ex vivo and toxicity depending on usage patterns in an animal model. British journal of pharmacology, 2023, Volume: 180, Issue:7 Topics: Analgesics, Opioid; Animals; Benzodiazepines; Cytochrome P-450 CYP3A; Diazepam; Drug Overdose; Humans; Mice; Models, Animal; Oxycodone; Oxymorphone	2023
Sex, estrous cycle, and hormone regulation of CYP2D in the brain alters oxycodone metabolism and analgesia. Biochemical pharmacology, 2022, Volume: 198 Topics: Analgesia; Analgesics, Opioid; Animals; Brain; Cytochrome P-450 Enzyme System; Estradiol; Estrous Cycle; Female; Male; Oxycodone; Oxymorphone; Pain; Progesterone; Propranolol; Rats; Rats, Wistar	2022
Rapid Extraction and Qualitative Screening of 30 Drugs in Oral Fluid at Concentrations Recommended for the Investigation of DUID Cases. Journal of analytical toxicology, 2022, Oct-14, Volume: 46, Issue:8 Topics: 2-Propanol; 3,4-Methylenedioxyamphetamine; Alprazolam; Amphetamines; Buprenorphine; Carisoprodol; Clonazepam; Cocaine; Codeine; Dronabinol; Fentanyl; Hexanes; Hydrocodone; Hydromorphone; Lorazepam; Meprobamate; Methadone; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Nordazepam; Oxazepam; Oxycodone; Oxymorphone; Pharmaceutical Preparations; Phencyclidine; Tandem Mass Spectrometry; Temazepam; Tramadol; Zolpidem	2022
A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use. Clinical biochemistry, 2023, Volume: 112 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Hydrocodone; Hydromorphone; Opioid-Related Disorders; Oxycodone; Oxymorphone; Tandem Mass Spectrometry	2023
A Cross-Sectional Study of Tampering in Xtampza ER, an Abuse-Deterrent Formulation of an Extended-Release Opioid, in a Treatment Center Population. Clinical drug investigation, 2023, Volume: 43, Issue:3 Topics: Abuse-Deterrent Formulations; Analgesics, Opioid; Cross-Sectional Studies; Delayed-Action Preparations; Humans; Opioid-Related Disorders; Oxycodone; Oxymorphone	2023
Enzalutamide Reduces Oxycodone Exposure in Men with Prostate Cancer. Clinical pharmacokinetics, 2023, Volume: 62, Issue:7 Topics: Analgesics, Opioid; Chromatography, Liquid; Humans; Male; Oxycodone; Oxymorphone; Pain; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Tandem Mass Spectrometry	2023