oxycodone and noroxycodone

oxycodone has been researched along with noroxycodone in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (8.33)18.2507
2000's17 (35.42)29.6817
2010's23 (47.92)24.3611
2020's4 (8.33)2.80

Authors

AuthorsStudies
Eddington, ND; Hassan, HE; Lee, IJ; Mason, CW; Myers, AL; Sinz, MW; Wang, D; Wang, H1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Kalso, E; Olkkola, KT; Pöyhiä, R; Seppälä, T1
Leow, KP; Smith, MT1
Benziger, DP; Burke, BE; Fitzmartin, RD; Goldenheim, PD; Kaiko, RF; Reder, RF1
Kirvela, M; Lindgren, L; Olkkola, KT; Seppala, T1
Heiskanen, TE; Kalso, EA; Ruismäki, PM; Seppälä, TA1
Davis, M; Reder, RF; Stambaugh, H; Stambaugh, JE; Stambaugh, MD1
Fowler, D; Levine, B; Moore, KA; Ramcharitar, V1
Howald, W; Lalovic, B; Phillips, B; Risler, LL; Shen, DD1
Boström, E; Hammarlund-Udenaes, M; Jansson, B; Simonsson, US1
Edwards, SR; Smith, MT2
Baldacci, A; Thormann, W1
Bachmakov, I; Brune, K; Cheremina, O; Fromm, MF; Hinz, B; Neubert, A1
Cooper, RM; Lee, MA; Leng, ME1
Edwards, SR; Huang, L; Smith, MT1
Kokki, H; Lasalmi, M; Lehtola, S; Ojanperä, I; Ranta, VP; Rasanen, I; Vanamo, K1
Kalso, EA; Kontinen, VK; Korpi, ER; Lemberg, KK; Siiskonen, AO; Viljakka, KM; Yli-Kauhaluoma, JT1
Chan, S; Edwards, SR; Smith, MT; Wyse, BD1
Chida, M; Hosokawa, T; Kamoto, T; Miura, T; Narabayashi, M; Nishimura, K; Onozawa, Y; Saijo, Y; Shimoyama, N; Takenoshita, S; Tani, K; Tsushima, T1
Neuvonen, M; Neuvonen, PJ1
Al-Asmari, AI; Anderson, RA; Cooper, GA1
Black, DL; Caplan, YH; Cawthon, B; Cone, EJ; Heltsley, R; Moser, F; Robert, T; Zichterman, A1
Grönlund, J; Hagelberg, NM; Laine, K; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Saari, TI1
Bourgogne, E; Hopfgartner, G; Varesio, E; Wagner, M1
Drewe, J; Hammann, F; Krähenbühl, S; Kummer, O; Moser, C; Schaller, O1
Andreassen, TN; Bjordal, K; Dale, O; Davies, A; Kaasa, S; Klepstad, P; Lundström, S1
Aantaa, R; Kuusniemi, K; Liukas, A; Neuvonen, M; Neuvonen, PJ; Olkkola, KT; Virolainen, P1
Kagawa, Y; Kawakami, J; Naito, T; Ohnishi, K; Takashina, Y; Tashiro, M; Yamamoto, K1
Anderson, H; Charles, B; Hardy, J; Norris, R; O'Shea, A1
Book, M; Lehmann, LE; Musshoff, F; Stamer, UM; Stuber, F; Zhang, L1
Black, DL; Cone, EJ; Flegel, RR; Heltsley, R; Lodico, CP; Mitchell, JM1
Ishida, T; Kawakami, J; Naito, T; Ohnishi, K; Tashiro, M1
Atayee, RS; Best, BM; Elder, NM; Ma, JD1
Dong, RH; Gao, HZ; Hao, GT; Li, YY; Liang, YG; Liu, ZY; Qu, HY; Wang, XF; Zhang, LJ; Zhou, HY1
Chayahara, N; Fujiwara, Y; Imamura, Y; Kiyota, N; Minami, H; Mukohara, T; Shimada, T; Toyoda, M1
Gaudette, F; Michaud, V; Sirhan-Daneau, A; St-Onge, M; Turgeon, J1
Cavallari, G; Croci Chiocchini, AL; Di Nino, G; Donati, G; Gori, A; La Manna, G; Mandrioli, R; Melotti, RM; Mercolini, L; Protti, M; Samolsky Dekel, BG; Vasarri, A1
Hautajärvi, H; Heikkinen, M; Hokkanen, J; Kokki, H; Kokki, M; Pitkänen, H; Ranta, VP; Sankilampi, U; Välitalo, P1
Brauneis, S; Busardò, FP; Forneris, A; Kyriakou, C; Marinelli, E; Pacifici, R; Pantano, F; Pichini, S1
Catapano, MC; Gerra, G; Mandrioli, R; Mercolini, L; Protti, M; Rudge, J; Samolsky Dekel, BG; Somaini, L1
Amico, P; Dickenmann, M; Duthaler, U; Hammann, F; Haschke, M; Jehle, AW; Kalbermatter, S; Krähenbühl, S; Lenherr, C; Leuppi-Taegtmeyer, A; Liechti, ME; Meyer Zu Schwabedissen, HE; Schmid, Y1
Batchelor, RH; Bornhop, DJ; Drabek, R; Gandhi, I; Jackson, GW; Kammer, MN; Kussrow, A1
Cashman, JR; de Kater, A; Gohdes, M; Schoenhard, G1
Cantillo, D; Chen, Y; Glotz, G; Kappe, CO1
Gréen, H; Jakobsson, G; Kronstrand, R; Larsson, R; Pellè, L1
Al-Qurain, AA; Mackenzie, L; Roberts, MS; Wiese, MD; Williams, DB1

Trials

14 trial(s) available for oxycodone and noroxycodone

ArticleYear
The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Amitriptyline; Chromatography, Gas; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Morphinans; Oxycodone; Oxymorphone; Placebos; Reference Values

1992
The pharmacokinetics of oxycodone in uremic patients undergoing renal transplantation.
    Journal of clinical anesthesia, 1996, Volume: 8, Issue:1

    Topics: Adult; Analgesics, Opioid; Biotransformation; Female; Half-Life; Humans; Injections, Intravenous; Kidney Transplantation; Male; Morphinans; Oxycodone; Oxymorphone; Uremia

1996
Morphine or oxycodone in cancer pain?
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:8

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Debrisoquin; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphinans; Morphine; Morphine Derivatives; Neoplasms; Oxycodone; Pain; Pain Measurement; Phenotype

2000
Double-blind, randomized comparison of the analgesic and pharmacokinetic profiles of controlled- and immediate-release oral oxycodone in cancer pain patients.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biological Availability; Chronic Disease; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain; Pain Measurement; Therapeutic Equivalency; Vomiting

2001
Comparison of oxycodone pharmacokinetics after buccal and sublingual administration in children.
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:7

    Topics: Administration, Buccal; Administration, Sublingual; Analgesics, Opioid; Area Under Curve; Child; Child, Preschool; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Indicators and Reagents; Infant; Male; Morphinans; Oxycodone; Oxymorphone

2006
Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: an open-label trial.
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:4

    Topics: Administration, Oral; Aged; Analgesics, Opioid; Constipation; Drug Administration Schedule; Female; Humans; Linear Models; Male; Middle Aged; Morphinans; Morphine; Morphine Derivatives; Nausea; Neoplasms; Oxycodone; Pain; Prospective Studies; Renal Insufficiency, Chronic; Sleep Stages; Treatment Outcome; Vomiting

2008
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:1

    Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Double-Blind Method; Drug Interactions; Genotype; Humans; Ketoconazole; Miosis; Morphinans; Oxycodone; Oxymorphone; Pain Measurement; Paroxetine; Placebos; Young Adult

2011
Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:5

    Topics: Analgesics, Opioid; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Linear Models; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain; Sex Factors

2011
Elimination of intravenous oxycodone in the elderly: a pharmacokinetic study in postoperative orthopaedic patients of different age groups.
    Drugs & aging, 2011, Jan-01, Volume: 28, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Area Under Curve; Chromatography, Liquid; Creatinine; Cytochrome P-450 CYP2D6; Female; Genotype; Glomerular Filtration Rate; Humans; Injections, Intravenous; Male; Middle Aged; Morphinans; Orthopedic Procedures; Oxycodone; Oxymorphone; Pain, Postoperative; Tandem Mass Spectrometry; Tissue Distribution; Young Adult

2011
CYP3A5*3 affects plasma disposition of noroxycodone and dose escalation in cancer patients receiving oxycodone.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:11

    Topics: Aged; Asian People; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Polymorphism, Genetic; Receptors, Opioid, mu

2011
Cancer cachexia raises the plasma concentration of oxymorphone through the reduction of CYP3A but not CYP2D6 in oxycodone-treated patients.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:8

    Topics: Aged; Analgesics, Opioid; Cachexia; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Humans; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Oxymorphone; Pain

2013
Effects of aprepitant on the pharmacokinetics of controlled-release oral oxycodone in cancer patients.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adult; Aged; Analgesics, Opioid; Aprepitant; Area Under Curve; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphinans; Morpholines; Neoplasms; Oxycodone; Oxymorphone; Pain

2014
Maturation of oxycodone pharmacokinetics in neonates and infants: Oxycodone and its metabolites in plasma and urine.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:4

    Topics: Age Factors; Analgesics, Opioid; Child, Preschool; Female; Half-Life; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Male; Morphinans; Oxycodone; Prospective Studies; Time Factors

2017
Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019, 04-01, Volume: 34, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Female; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Morphinans; Naloxone; Narcotic Antagonists; Oxycodone; Oxymorphone; Prognosis; Renal Dialysis; Tissue Distribution

2019

Other Studies

34 other study(ies) available for oxycodone and noroxycodone

ArticleYear
Induction of xenobiotic receptors, transporters, and drug metabolizing enzymes by oxycodone.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Animals; Cell Line, Tumor; Gene Expression; Humans; Liver; Male; Oxycodone; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Drug; Transcriptional Activation; Xenobiotics

2013
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats.
    Life sciences, 1994, Volume: 54, Issue:17

    Topics: Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Morphinans; Morphine; Naloxone; Nociceptors; Oxycodone; Rats; Rats, Sprague-Dawley

1994
Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:1

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Reference Values

1996
Tentative identification of novel oxycodone metabolites in human urine.
    Journal of analytical toxicology, 2003, Volume: 27, Issue:6

    Topics: Analgesics, Opioid; Chromatography, Gas; Forensic Medicine; Humans; Morphinans; Oxycodone; Substance Abuse Detection

2003
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Metabolic Clearance Rate; Methylation; Microsomes; Microsomes, Liver; Molecular Structure; Morphinans; Oxidoreductases, N-Demethylating; Oxycodone; Oxymorphone; Protein Binding; Quinidine

2004
The use of liquid chromatography/mass spectrometry for quantitative analysis of oxycodone, oxymorphone and noroxycodone in Ringer solution, rat plasma and rat brain tissue.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:21

    Topics: Analgesics, Opioid; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Injections, Intravenous; Isotonic Solutions; Morphinans; Oxycodone; Oxymorphone; Rats; Reproducibility of Results; Ringer's Solution; Spectrometry, Mass, Electrospray Ionization

2004
Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Jan-25, Volume: 814, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Morphinans; Morphine; Morphine Derivatives; Oxycodone; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2005
Analysis of oxycodol and noroxycodol stereoisomers in biological samples by capillary electrophoresis.
    Electrophoresis, 2005, Volume: 26, Issue:10

    Topics: Electrophoresis, Capillary; Humans; Liver; Morphinans; Oxycodone; Stereoisomerism

2005
Simultaneous determination of oxycodone and its major metabolite, noroxycodone, in human plasma by high-performance liquid chromatography.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:10

    Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Morphinans; Oxycodone; Sensitivity and Specificity; Ultraviolet Rays

2005
Measurements of plasma oxycodone, noroxycodone and oxymorphone levels in a patient with bilateral nephrectomy who is undergoing haemodialysis.
    Palliative medicine, 2005, Volume: 19, Issue:3

    Topics: Analgesics, Opioid; Female; Humans; Kidney Failure, Chronic; Middle Aged; Morphinans; Nephrectomy; Oxycodone; Oxymorphone; Renal Dialysis

2005
Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague--Dawley rats: influence of streptozotocin-induced diabetes.
    Pharmaceutical research, 2005, Volume: 22, Issue:9

    Topics: Alcohol Oxidoreductases; Analgesics, Opioid; Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P450 Family 2; Diabetes Mellitus, Experimental; Male; Morphinans; Oxycodone; Rats; Rats, Sprague-Dawley; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Streptozocin

2005
Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.
    Anesthesiology, 2006, Volume: 105, Issue:4

    Topics: Algorithms; Analgesics, Opioid; Animals; Area Under Curve; Autoradiography; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intravenous; Injections, Spinal; Male; Morphinans; Morphine; Motor Activity; Oxycodone; Oxymorphone; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction

2006
Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Apr-01, Volume: 848, Issue:2

    Topics: Analgesics, Opioid; Animals; Calibration; Chromatography, High Pressure Liquid; Injections, Intravenous; Male; Molecular Structure; Morphinans; Oxycodone; Oxymorphone; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2007
Sex differences in the pharmacokinetics, oxidative metabolism and oral bioavailability of oxycodone in the Sprague-Dawley rat.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Biological Availability; Female; Male; Morphinans; Oxidation-Reduction; Oxycodone; Oxymorphone; Rats; Rats, Sprague-Dawley; Sex Characteristics

2008
Determination of oxycodone, noroxycodone, oxymorphone, and noroxymorphone in human plasma by liquid chromatography-electrospray-tandem mass spectrometry.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:3

    Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Morphinans; Oxycodone; Oxymorphone; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2008
Oxycodone-related fatalities in the west of Scotland.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:8

    Topics: Adult; Aged; Cause of Death; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Morphinans; Mortality; Narcotics; Oxycodone; Reproducibility of Results; Scotland; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry

2009
Urine testing for norcodeine, norhydrocodone, and noroxycodone facilitates interpretation and reduces false negatives.
    Forensic science international, 2010, May-20, Volume: 198, Issue:1-3

    Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; False Negative Reactions; Forensic Toxicology; Humans; Hydrocodone; Medication Adherence; Morphinans; Oxycodone; Oxymorphone; Pain; Tandem Mass Spectrometry

2010
Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:4

    Topics: Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Humans; Injections, Intravenous; Itraconazole; Morphinans; Oxidation-Reduction; Oxycodone; Oxymorphone

2010
Quantitation of polar analytes using column-switching: application to oxycodone and three metabolites in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Mar-01, Volume: 878, Issue:7-8

    Topics: Chromatography, Liquid; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Morphinans; Oxycodone; Oxymorphone; Perchlorates; Reproducibility of Results; Sensitivity and Specificity

2010
Is saliva a valid substitute for plasma in pharmacokinetic studies of oxycodone and its metabolites in patients with cancer?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Morphinans; Neoplasms; Oxycodone; Patient Preference; Saliva; Tandem Mass Spectrometry; Time Factors; Young Adult

2012
CYP2D6 genotype dependent oxycodone metabolism in postoperative patients.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Aged; Analgesics, Opioid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Female; Genotype; Humans; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Spectrometry, Mass, Electrospray Ionization

2013
Prescription opioids. I. Metabolism and excretion patterns of oxycodone in urine following controlled single dose administration.
    Journal of analytical toxicology, 2013, Volume: 37, Issue:5

    Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Employment; Female; Humans; Male; Morphinans; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Time Factors; Workplace; Young Adult

2013
Observations of urinary oxycodone and metabolite distributions in pain patients.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Analgesics, Opioid; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Pain; Retrospective Studies; Sex Factors; Specimen Handling; Tandem Mass Spectrometry; Young Adult

2014
Pharmacokinetics of oxycodone hydrochloride and three of its metabolites after intravenous administration in Chinese patients with pain.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Adult; Analgesics, Opioid; Area Under Curve; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Pain

2014
Development of a sensitive method for the determination of oxycodone and its major metabolites noroxycodone and oxymorphone in human plasma by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Jan-01, Volume: 1008

    Topics: Chromatography, Liquid; Humans; Limit of Detection; Morphinans; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry

2016
Dialyzability of Oxycodone and Its Metabolites in Chronic Noncancer Pain Patients with End-Stage Renal Disease.
    Pain practice : the official journal of World Institute of Pain, 2017, Volume: 17, Issue:5

    Topics: Adult; Analgesics, Opioid; Chronic Disease; Chronic Pain; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Renal Dialysis

2017
Determination of oxycodone and its major metabolites noroxycodone and oxymorphone by ultra-high-performance liquid chromatography tandem mass spectrometry in plasma and urine: application to real cases.
    Clinical chemistry and laboratory medicine, 2017, Aug-28, Volume: 55, Issue:9

    Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Morphinans; Oxycodone; Oxymorphone; Tandem Mass Spectrometry

2017
Determination of oxycodone and its major metabolites in haematic and urinary matrices: Comparison of traditional and miniaturised sampling approaches.
    Journal of pharmaceutical and biomedical analysis, 2018, Apr-15, Volume: 152

    Topics: Blood Specimen Collection; Body Fluids; Chromatography, Liquid; Doping in Sports; Dried Blood Spot Testing; Drug Monitoring; Humans; Miniaturization; Morphinans; Oxycodone; Oxymorphone; Plasma; Specimen Handling; Tandem Mass Spectrometry; Urine

2018
Quantification of Opioids in Urine Using an Aptamer-Based Free-Solution Assay.
    Analytical chemistry, 2019, 08-20, Volume: 91, Issue:16

    Topics: Analgesics, Opioid; Aptamers, Nucleotide; Fentanyl; Humans; Hydrocodone; Molecular Structure; Morphinans; Oxycodone

2019
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:2

    Topics: Analgesics, Opioid; Animals; Cytochrome P-450 Enzyme System; Female; Hemoglobins; Humans; Male; Mixed Function Oxygenases; Morphinans; NADP; Oxides; Oxycodone; Oxymorphone; Rats

2020
Organophotocatalytic N-Demethylation of Oxycodone Using Molecular Oxygen.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Mar-02, Volume: 26, Issue:13

    Topics: Analgesics; Demethylation; Humans; Morphinans; Oxycodone

2020
Oxycodone findings and CYP2D6 function in postmortem cases.
    Forensic science international. Genetics, 2021, Volume: 53

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Cytochrome P-450 CYP2D6; DNA Copy Number Variations; Female; Forensic Genetics; Genotype; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Morphinans; Oxycodone; Pharmacogenomic Testing; Phenotype; Polymorphism, Single Nucleotide; Young Adult

2021
Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetr
    Journal of pharmaceutical and biomedical analysis, 2021, Sep-05, Volume: 203

    Topics: Aged; Chromatography, Liquid; Fentanyl; Humans; Morphinans; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry; Tramadol

2021