oxycodone has been researched along with morphine in 485 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (3.09) | 18.7374 |
| 1990's | 30 (6.19) | 18.2507 |
| 2000's | 111 (22.89) | 29.6817 |
| 2010's | 243 (50.10) | 24.3611 |
| 2020's | 86 (17.73) | 2.80 |
| Authors | Studies |
|---|---|
| Bousquet, AR; Howes, JF; Kotick, MP; Leland, DL; Polazzi, JO | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Aceto, MD; Coop, A; Greiner, E; Harris, LS; Schmidhammer, H; Spetea, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Fink, M; Kirchmair, J; Langer, T; Music, M; Rief, S; Rollinger, JM; Schmidhammer, H; Schuster, D; Schütz, J; Spetea, M; Stuppner, H; Wolber, G | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Coe, JW; Ghavimi, B; Magnus, P | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bánki, L; Deli, MA; Dvorácskó, S; Horváth, G; Kékesi, G; Keresztes, A; Macedonio, G; Mollica, A; Pieretti, S; Stefanucci, A; Tömböly, C; Tuboly, G; Walter, FR; Zádor, F | 1 |
| Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B | 1 |
| Halpern, LM | 1 |
| Beaver, WT; Houde, RW; Rogers, A; Wallenstein, SL | 1 |
| Korcok, M | 1 |
| Basmanov, SN; Treshchinskiĭ, AI | 1 |
| Ramanathan, S; Turndorf, H; Zakowski, MI | 1 |
| Kalso, EA; Pöyhiä, R | 1 |
| Ennis, M; Lorenz, W; Nehring, E; Schneider, C | 1 |
| Atchison, NE; Carr, DB; Osgood, PF; Szyfelbein, SK | 1 |
| Kalso, E; Linko, K; Onnela, P; Pöyhiä, R; Tammisto, T; Tigerstedt, I | 1 |
| Kalso, E; Mattila, MJ; Rosenberg, PH; Seppälä, T; Vainio, A | 1 |
| Kalso, E; Vainio, A | 2 |
| Foley, KM; Houde, RW; Inturrisi, CE; Moulin, DE; Nip, TJ; Reidenberg, B; Wallenstein, S; Weinberg, DS | 1 |
| Asantila, R; Rosenberg, PH; Scheinin, B | 1 |
| Hopper, M; Kantor, TG; Laska, E | 1 |
| Heino, A; Rosenberg, PH; Scheinin, B | 1 |
| Butz, RF; Findlay, JW; Jones, EC | 1 |
| Dietzen, DJ; Koenig, J; Turk, J | 1 |
| Duttaroy, A; Yoburn, BC | 1 |
| Bochner, F; Cleary, J; Mikus, G; Somogyi, A | 1 |
| Sheidler, VR | 1 |
| Leow, KP; Smith, MT | 1 |
| Cramond, T; Leow, KP; Smith, MT; Wright, AW | 1 |
| Niemi, L; Pitkänen, MT; Rosenberg, PH; Tuominen, MK | 1 |
| Anand, A; Carmosino, L; Glatt, AE | 1 |
| Glare, PA; Walsh, TD | 1 |
| Abbott, F; Hayball, P; Maddocks, I; Parker, D; Somogyi, A | 1 |
| Backlund, M; Kajimoto, Y; Lindgren, L; Rosenberg, PH | 1 |
| Manfredi, B; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
| Heiskanen, T; Kalso, E | 1 |
| Huhtala, J; Lindgren, L; Tarkkila, P; Tuominen, M | 1 |
| Pitkänen, M; Rosenberg, P; Seppälä, T; Silvasti, M; Svartling, N | 1 |
| Babul, N; Belzile, M; Bruera, E; Darke, A; Fainsinger, R; Ford, I; Harsanyi, Z; Pituskin, E | 1 |
| Jamison, RN; Katz, NP; Nedeljkovic, SS; Raymond, SA; Slawsby, EA | 1 |
| Ashby, MA; Jackson, KA; Martin, P | 1 |
| Comerford, T | 1 |
| Doona, M; Walsh, D; Zhukovsky, DS | 1 |
| Kirvelä, O; Leino, K; Lertola, K; Mildh, L; Seppälä, T | 1 |
| Brown, J; Clark, P; Curtis, GB; Johnson, GH; Lacouture, PG; O'Callaghan, R; Shi, M; Taylor, R | 1 |
| Ross, FB; Smith, MT; Wallis, SC | 1 |
| Bohrer, A; Koenig, J; Nowatzke, W; Saunders, A; Turk, J; Zeng, J | 1 |
| Dahl, JL; Gilson, AM; Joranson, DE; Ryan, KM | 1 |
| Anis, NA; Azer, NL; Bangalore, MS; Eldefrawi, ME; Nath, N; O'Connell, KP; Schwartz, RP; Wright, J | 1 |
| Kirvelä, OA; Mildh, LH; Scheinin, M; Tuomisto, LM | 1 |
| Miller, A | 1 |
| Nielsen, CK; Ross, FB; Smith, MT | 1 |
| Arcuri, E; Centulio, F; Ciocca, F; D'Angiolino, G; Ginobbi, P; Marcelli, ME; Pelagalli, L; Tirelli, W | 1 |
| Heiskanen, TE; Kalso, EA; Ruismäki, PM; Seppälä, TA | 1 |
| Casas, JR; Cherny, N; Conno, F; Hanks, GW; Hanna, M; Kalso, E; McQuay, HJ; Mercadante, S; Meynadier, J; Poulain, P; Radbruch, L; Ripamonti, C; Sawe, J; Twycross, RG; Ventafridda, V | 1 |
| de Wit, R; Enting, RH; Lieverse, PJ; Smitt, PA; van der Rijt, CC; Wilms, EB | 1 |
| Taylor, MS | 1 |
| Burgess, FW | 1 |
| Cairns, R | 1 |
| Reder, RF | 1 |
| Jones, J; Moore, C; Tomlinson, K | 1 |
| Davis, MP; Dickerson, D; Lagman, R; LeGrand, SB; Varga, J; Walsh, D | 1 |
| Gallagher, RM; Gracely, E; Hall, S; Knowlton, C; Wescules, D | 1 |
| Gutierrez, S; Zacny, JP | 1 |
| ROESCH, E | 1 |
| BLOOMQUIST, ER | 1 |
| STYNLER, FE; WEISS, U | 1 |
| BUCKETT, WR | 1 |
| Lauretti, GR; Oliveira, GM; Pereira, NL | 1 |
| Berger, A; Delea, TE; Goodman, S; Hoffman, DL; Oster, G; Seifeldin, R | 1 |
| Borchgrevink, PC; Kaasa, S; Klepstad, P; Kongsgaard, UE | 1 |
| Markowitz, J; Schein, J; Staats, PS | 1 |
| Dohi, S; Yanagidate, F | 1 |
| Aceto, MD; Beardsley, PM; Bowman, ER; Cook, CD; Harris, LS; Newman, JL | 1 |
| Adler, R; Eisenberg, E; Grach, M; Massalha, W; Pud, D | 1 |
| Akizuki, A; Shimoyama, M; Shimoyama, N; Takahashi, H | 1 |
| Oster, P; Schuler, M | 1 |
| Walsh, D | 1 |
| Cook, CD; Nickerson, MD | 1 |
| Edwards, SR; Smith, MT | 1 |
| Hattori, S; Kimura, N; Noguchi, T; Takatani, J | 1 |
| Kelley, A; Martitsch, C; Nascimento, MC; Obermair, A; Weidner, I | 1 |
| Hanks, GW; Reid, C | 1 |
| de la Iglesia, FA; Smith, MT | 1 |
| Kam, PC; Ladd, LA; Mather, LE; Smith, MT; Williams, DB; Wright, AW | 1 |
| Ogrin, C; Schussler, GC | 1 |
| Jung, BF; Reidenberg, MM | 1 |
| Calello, DP; Osterhoudt, KC; Shieh-Czaja, A | 1 |
| du Bois, R; Goller, K; Riley, J; Ross, JR; Rutter, D; Wells, AU; Welsh, K | 1 |
| Compton, WM; Volkow, ND | 1 |
| Davis, JJ; Dillon, JD; Egan, TD; Hall, RH; Johnson, KB; Niu, SY; Pace, NL; Swenson, JD | 1 |
| Lindena, G; Müller-Busch, HC; Tietze, K; Woskanjan, S | 1 |
| Narita, M; Niikura, K; Ozaki, M; Suzuki, T; Yajima, Y | 1 |
| Kamei, J; Nozaki, C; Saitoh, A; Tamura, N | 1 |
| Calder, CT; O'Connor, DP; Woods, GW | 1 |
| Bailey, JE; Barton, PL; Dart, RC; Lezotte, D; Lowenstein, SR | 1 |
| Andersen, SD; Arendt-Nielsen, L; Christrup, LL; Drewes, AM; Staahl, C | 1 |
| Okada, M; Shinjo, T | 1 |
| Kalso, E; Kontinen, VK; Kylänlahti, I; Lemberg, K; Viljakka, K; Yli-Kauhaluoma, J | 1 |
| Akre, O; Bergenwald, L; Gustafsson, O; Hohwü, L; Törnblom, M | 1 |
| Nicholson, B; Ross, E; Sasaki, J; Weil, A | 1 |
| Naliboff, BD; Pham, Q; Wu, SM | 1 |
| Bug, C; Earnshaw, S; Greiner, W; Lehmann, K; Sabatowski, R | 1 |
| Kalso, EA; Kontinen, VK; Korpi, ER; Lemberg, KK; Siiskonen, AO; Viljakka, KM; Yli-Kauhaluoma, JT | 1 |
| Alleyne, CH; French, A; Macomson, SD; Rahimi, SY; Smith, JR; Vender, JR | 1 |
| Comfort, C; Kogan, M; Moryl, N; Obbens, E | 1 |
| Morden, NE; Ross-Degnan, D; Roughead, E; Simoni-Wastila, L; Soumerai, S; Sullivan, SD; Zerzan, JT; Zhang, F | 1 |
| Reid, C | 1 |
| Kumar, P; Pawar, M; Sirohi, S; Sunkaraneni, S; Walker, EA; Yoburn, BC | 1 |
| Andersen, SD; Arendt-Nielsen, L; Christrup, LL; Dimcevski, G; Drewes, AM; Staahl, C; Thorsgaard, N | 1 |
| Edwards, SR; Lotfipour, S; Nielsen, CK; Ross, FB; Saini, KS; Smith, MT | 1 |
| Ahmad, R; Davies, AN; Hirani, E; Hume, SP; Lingford-Hughes, AR; Nataf, V; Nutt, DJ | 1 |
| Crudele, N; Haddox, JD | 1 |
| Blumenthal, S; Borgeat, A; Marquardt, M; Min, K | 1 |
| Imai, S; Miyoshi, K; Nakamura, A; Narita, M; Ozaki, M; Suzuki, M; Suzuki, T | 1 |
| Arbuckle, R; Bruera, E; Curry, EA; Hung, F; Palla, S | 1 |
| Lin, H; Ling, JY; Luo, WB; Sun, XF; Xia, Y; Zhen, ZJ; Zheng, L | 1 |
| Lichtor, SA; Zacny, JP | 1 |
| Friedrichsdorf, SJ; Kang, TI | 1 |
| Kalso, E | 1 |
| Gooberman-Hill, R; Hanks, GW; Reid, CM | 1 |
| Lavine, G | 2 |
| Raffa, RB; Stone, DJ | 1 |
| Boström, E; Hammarlund-Udenaes, M; Simonsson, US | 1 |
| Chida, M; Hosokawa, T; Kamoto, T; Miura, T; Narabayashi, M; Nishimura, K; Onozawa, Y; Saijo, Y; Shimoyama, N; Takenoshita, S; Tani, K; Tsushima, T | 1 |
| Hanaoka, K; Hosokawa, T; Ishida, T; Kitajima, T; Mashimo, S; Miyazaki, T; Namiki, A; Nogami, S; Ogawa, S | 1 |
| Challand, S; Frew, K | 1 |
| Arendt-Nielsen, L; Christrup, LL; Drewes, AM; Foster, DJ; Hansen, SH; Kristensen, K; Staahl, C; Upton, R | 1 |
| Benyamin, R; Glaser, SE; Hansen, H; Manchikanti, L; Patel, S; Trescot, AM | 1 |
| Bruera, E; Hanson, J; Pereira, J; Tarumi, Y; Watanabe, S | 1 |
| Güttler, K; Sabatowski, R | 1 |
| Blondell, RD; Purdy, CH; Wisniewski, AM | 1 |
| Arttamangkul, S; Low, MJ; Pintar, J; Quillinan, N; von Zastrow, M; Williams, JT | 1 |
| Baranchuk, A; Gibson, K; Methot, M; Simpson, CS; Strum, D | 1 |
| MacPherson, R; Pattullo, GG | 1 |
| Ito, H; Kato, A; Kihara, T; Matsumoto, M; Minami, K; Narita, M; Orita, S; Suzuki, T; Tomii, T | 1 |
| Bailey, JE; Campagna, E; Dart, RC | 1 |
| Doyle, CA; Hruby, G; Loadsman, JA | 1 |
| Berkelhammer, DL; Brzeski, A; Coats, BD; Crysdale, NY; Hutchinson, MR; Johnson, KW; Judd, CM; Lewis, SS; Maier, SF; Northcutt, A; Skyba, DA; Vietz, CM; Watkins, LR | 1 |
| Biros, MH; Gray, RO; Miner, JR; Moore, J; Skinner, L | 1 |
| Dumas, EO; Pollack, GM | 1 |
| Challand, S; Frew, K; Regnard, C | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z | 1 |
| Hass, B; Hertel, N; Kotowa, W; Liedgens, H; Lungershausen, J; Poulsen Nautrup, B | 1 |
| Hashimoto, S; Kuzumaki, N; Nakamura, A; Narita, M; Ozeki, A; Satoshi, I; Suzuki, T; Uezono, Y | 1 |
| Bandieri, E; Chiarolanza, A; Luppi, M; Magrini, N; Marata, AM; Ripamonti, C | 1 |
| Amano, T; Hashimoto, K; Kasakura, A; Kuzumaki, N; Narita, M; Sakai, N; Sora, I; Suzuki, T; Uhl, GR | 1 |
| Brill, S; Halpern, P; Hertz, D; Meissner, W; Or, J; Zaslansky, R | 1 |
| Giusti, P; Guidolin, D; Passarella, L; Pulzato, L; Tegon, G; Zusso, M | 1 |
| Browning, RM; McDonnell, NJ; Nathan, EA; Paech, MJ | 1 |
| Brosen, K; Enggaard, TP; Mikkelsen, S; Sindrup, SH; Zwisler, ST | 1 |
| Hasegawa, M; Ito, H; Kanemasa, T; Kato, A; Kihara, T; Koike, K; Masuno, K; Matsumoto, M; Matsushima, S; Minami, K; Miyoshi, T; Nakamura, A; Narita, M; Orita, S; Shimada, S; Suzuki, T; Tomii, T; Torii, M | 1 |
| Bjerkelund, CE; Lenz, H; Qvigstad, E; Raeder, J; Sandvik, L | 1 |
| Gnjidic, D; Hilmer, SN; Murnion, BP | 1 |
| Ise, Y; Katayama, S; Miura, Y; Shimizu, H; Wako, T | 1 |
| Bonanno, LM; Delouise, LA | 1 |
| Dahn, T; Gunn, J; Kriger, S; Terrell, AR | 1 |
| Ahn, JS; Kim, DY; Kim, SY; Ryoo, BY; Shin, DB; Song, HS; Yim, CY | 1 |
| Gingras, M; Laberge, MH; Lefebvre, M | 1 |
| Kawagoe, K; Matsuura, S; Tajitsu, T | 1 |
| Bruchas, MR; Chavkin, C; Melief, EJ; Miyatake, M | 1 |
| Gomella, LG; Lallas, CD; Patel, J; Trabulsi, EJ; Viscusi, ER | 1 |
| Pergolizzi, JV; Raffa, RB; Segarnick, DJ; Tallarida, RJ | 1 |
| Arendt-Nielsen, L; Drewes, AM; Olesen, AE; Staahl, C | 1 |
| Hatton, KW; Lofwall, MR; Nuzzo, PA; Stoops, WW; Walsh, SL | 1 |
| Borchgrevink, PC; Dale, O; Fredheim, OM; Kaasa, S | 1 |
| Chang, SH; Langford, RM; Maney, KM; Mehta, V; Phillips, JP | 1 |
| Bohn, LM; Raehal, KM | 1 |
| Mueller-Lissner, S | 1 |
| Pergolizzi, JV; Raffa, RB | 1 |
| Adams, JB; Berend, KR; Lombardi, AV | 1 |
| Bonanno, LM; DeLouise, LA; Kwong, TC | 1 |
| Aragaki, D; Baria, A; Bolus, R; Davis, F; Naliboff, BD; Pham, Q; Schieffer, B; Shekelle, P; Van Vort, W; Wu, SM | 1 |
| Bhalla, S; Gulati, A; Rapolaviciute, V | 1 |
| Fang, WX; Li, F; Sima, L; Wu, XM | 1 |
| Davidson, AJ; Palmer, GM; Teo, JH | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A | 2 |
| Alford, I; Shan, X; Tiscione, NB; Yeatman, DT | 1 |
| Fujimoto, S; Hosokawa, T; Kanbayashi, Y; Konishi, H; Miki, T; Okamoto, K; Otsuji, E; Takagi, T; Taniwaki, M; Yoshikawa, T | 1 |
| Dunn, G; Goodwin, L; Graham-Woollard, T; Hunter, JD; Mitchell, PA; Pearson, D; Rothwell, MP | 1 |
| De Vry, J; Rutten, K; Tzschentke, TM; van der Kam, EL | 1 |
| Christophersen, AS; Johansen, U; Oiestad, AM; Oiestad, EL | 1 |
| Christoph, T; De Vry, J; Schiene, K; Tallarida, RJ; Tzschentke, TM | 1 |
| Bland, JM; Clark, AL; Cleland, JG; Johnson, MJ; Oxberry, SG; Torgerson, DJ | 1 |
| Dale, O; Kaasa, S; Klepstad, P; Moksnes, K; Paulsen, O; Rosland, JH | 1 |
| Asato, M; Devi, LA; Hojo, M; Imai, S; Kuzumaki, N; Nakamura, A; Narita, M; Ozeki, A; Rahmadi, M; Sudo, Y; Suzuki, T; Uezono, Y | 1 |
| Ganesh, A; Goebel, T; Gurnaney, HG; Kraemer, FW; Maxwell, LG; Nance, ML | 1 |
| Fanning, J; Hojat, R | 1 |
| Farrell, MP; Hall, WD | 1 |
| Bruno, R; Burns, L; Larance, B; Roxburgh, A | 1 |
| Kutner, JS; Linnebur, SA; O'Bryant, CL; Yamashita, TE | 1 |
| Suzuki, T | 1 |
| Carlson, N; Hartrick, CT; Hartrick, S; Pestano, C | 1 |
| Abrams, DI; Benowitz, NL; Couey, P; Kelly, ME; Shade, SB | 1 |
| Cromarty, H; Dooley, J; Hopman, W; Kelly, L; Madden, S; Minty, B; Morgan, A | 1 |
| Ware, MA | 1 |
| Habu-Tomita, N; Hamaguchi, K; Hasegawa, M; Hashimoto, H; Inoue, Y; Ito, H; Iwamoto, Y; Kato, A; Kihara, T; Koike, K; Koyabu, K; Minami, K; Nakamura, A; Nanba, K; Narita, M; Nishino, I; Noshi, E; Okabayashi, Y; Suzuki, T | 1 |
| Hendrickson, RG; McKeown, NJ | 1 |
| Araki, H; Ikesue, H; Ishihara, M; Itoh, Y; Kitaichi, K; Matsunaga, H; Oishi, R; Sendo, T; Suemaru, K; Suetsugu, K | 1 |
| Mercadante, S | 1 |
| Halmesmäki, E; Halonen, P; Kainu, JP; Korttila, KT; Puro, H; Sarvela, J; Toivonen, HJ | 1 |
| Baxter, G; Conway, P; Hertel, N; Ikenberg, R; Liedgens, H; Moore, RA; Obradovic, M | 1 |
| Dale, O; Kaasa, S; Moksnes, K; Paulsen, Ø; Rosland, JH; Spigset, O | 1 |
| Förster, JG; Kuusniemi, KS; Leino, KA; Mäkelä, K; Neuvonen, PJ; Pitkänen, MT; Rikalainen-Salmi, R; Virolainen, P | 1 |
| Webster, L | 1 |
| Nicholson, BD | 1 |
| Fujii, S; Ikeda, M; Koike, Y; Kubo, S; Kurebayashi, J; Mizutou, A; Nakashima, K; Nomura, T; Oota, Y; Saitou, W; Seki, M; Shiiki, S; Shimo, T; Sonoo, H; Tanaka, K; Yamamoto, Y; Yamashita, T | 1 |
| Chen, BC; Hoffman, RS | 1 |
| Neelakantan, H; Walker, EA | 1 |
| Birnbaum, AK; Harmon, TM; Jones, JM; Le Naour, M; Pentel, PR; Portoghese, PS; Pravetoni, M; Raleigh, MD; Tucker, AM | 1 |
| Bergen, H; Gunnell, D; Hawton, K; Kapur, N; Simkin, S; Wells, C | 1 |
| Chang, CB; Jeon, YT; Kang, YG; Kim, TK; Koh, IJ; Song, J | 1 |
| Hoeben, E; Mangold, B; Reitmeir, P; Rusch, S; Schaffler, K; Smit, JW; Upmalis, D | 1 |
| Bäthis, H; Böhmer, A; Joppich, R; Kelen, R; Lefering, R; Neugebauer, E; Otto, C; Petzke, F; Richards, P; Stern, W; Treptau, T; Zarghooni, K | 1 |
| Aagaard, L; Andersen, SE; Glintborg, D; Moreno, SI; Poulsen, KK; Thirstrup, S | 1 |
| Ball, K; Bouzom, F; Declèves, X; Scherrmann, JM; Walther, B | 1 |
| Häkkinen, M; Launiainen, T; Ojanperä, I; Vuori, E | 1 |
| Hasegawa, M; Kanbara, T; Kato, A; Minami, K; Nakamura, A; Narita, M; Nishiyori, A; Suzuki, T; Tomii, T | 1 |
| Viswesh, VV | 1 |
| Nelson, L; Perrone, J; Portelli, I; Wightman, R | 1 |
| Candish, E; Dawes, PA; Gooley, A; Hilder, EF; Shellie, RA; Wirth, HJ | 1 |
| Pappagallo, M; Sokolowska, M | 1 |
| Glaeske, G; Hoffmann, F; Windt, R | 1 |
| Tenore, PL | 1 |
| Gotoh, K; Sakurada, T; Satoh, N; Suzuki, M; Watanabe, S | 1 |
| Mankes, RF; Silver, CD | 1 |
| Ha, YC; Jang, EC; Kang, H; Kim, JY; Lee, JS; Woo, YC | 1 |
| Bland, JM; Clark, AL; Cleland, JG; Johnson, MJ; Oxberry, SG | 1 |
| Falke, D; Gálvez, R; Hans, G; Schäfer, M; Steigerwald, I | 1 |
| Gimbel, JS; Kelen, R; Minkowitz, HS; Richards, P; Stern, W | 1 |
| Kelen, R; Richards, P; Riff, D; Stern, W | 1 |
| Drewes, AM; Olesen, AE; Osther, PJ; Pedersen, KV | 1 |
| Addante, RA; Charlson, MD; Michelson, JD | 1 |
| Comer, SD; Cooper, ZD; Jones, JD; Kowalczyk, WJ; Manubay, JM; Metz, VE; Peyser, D; Saccone, PA; Smith, ME; Sullivan, MA; Vosburg, SK | 1 |
| Bohlman, HH; Cassinelli, EH; Furey, CG; Garcia, RM; Messerschmitt, PJ | 1 |
| Fujita, M; Hasegawa, M; Hongo, Y; Kanbara, T; Kato, A; Mori, T; Morioka, Y; Nakamura, A; Nishiyori, A; Ogawa, K; Ono, H; Sakaguchi, G; Shibasaki, M; Suzuki, T | 1 |
| Bradshaw, DH; Chapman, CR | 1 |
| Foltan, V; Hudec, R; Kristova, V; Tisonova, J | 1 |
| Pergolizzi, JV; Raffa, RB; Taylor, R | 1 |
| Abbasi, S; Farsi, D; Fathi, M; Ghalyaie, AH; Hafezimoghadam, P; Zare, MA | 1 |
| Blome, CJ; Fischer, H; Goliasch, G; Koinig, H; Makarova, N; Nabecker, S; Rinoesl, H; Ruetzler, K; Sessler, DI | 1 |
| Raeder, J | 1 |
| Calvino, B; Dubacq, S; Marchand, F; McMahon, SB; Pezet, S; Rivals, I; Thibault, K | 1 |
| Mazer-Amirshahi, M; Mullins, PM; Pines, JM; Rasooly, I; van den Anker, J | 1 |
| Kuo, A; Meutermans, W; Smith, MT; Wyse, BD | 1 |
| Ahmedzai, SH; Boland, JW; Foulds, GA; Pockley, AG | 1 |
| Fayers, P; Fladvad, T; Kaasa, S; Klepstad, P; Skorpen, F | 1 |
| Carroll, E; Conroy, L; Curran, HV; Jones, L; Kamboj, SK; Tookman, A | 1 |
| Chen, LC; Knaggs, RD; Zin, CS | 1 |
| Visoiu, M | 1 |
| Derry, S; Moore, RA; Wiffen, PJ | 1 |
| Wolfe, SM | 1 |
| Kanbara, T; Kanemasa, T; Minami, K; Nakamura, A; Ono, H; Sakaguchi, G; Shinohara, S | 1 |
| Branford, R; Droney, J; Gretton, S; Kennett, A; Oyebode, C; Riley, J; Ross, J; Sato, H; Thick, M; Wells, A; Welsh, K; Williams, J | 1 |
| Bailey, M; Boyd, D; Kavnoudias, H; Konstantatos, AH; Lyon, SM; Stegeman, JR; Street, M; Thomson, KR | 1 |
| Chittams, J; Fudin, J; Kang, Y; Mao, JJ; McMenamin, E; Meghani, SH | 1 |
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| Amgott-Kwan, AT; Zadina, JE | 1 |
| Figg, WD; Smith, DM | 1 |
| Ajao, A; Chai, GP; Ding, Y; Gill, R; Karami, S; Major, JM; McAninch, J; Meyer, T; Secora, A; Wong, J; Zhang, D; Zhao, Y | 1 |
| Boland, JW | 1 |
| Aruldhas, BW; Montelibano, A; Overholser, BR; Packiasabapathy, S; Quinney, SK; Raymond, O; Sadhasivam, S; Sivam, I; Sivam, S; Velu, S | 1 |
| Hui, D; Ikari, T; Imai, K; Inoue, A; Inoue, S; Matsuda, Y; Matsumoto, Y; Matsunuma, R; Miwa, S; Mori, M; Morita, T; Okamoto, S; Satomi, E; Suzuki, K; Watanabe, H; Yamaguchi, T; Yamauchi, T; Yokomichi, N | 1 |
| Ciapała, K; Ciechanowska, A; Mika, J; Pawlik, K; Rojewska, E | 1 |
| Barrett, JE; Inan, S; Shekarabi, A | 1 |
| Kitahara, H; Komatsu, S; Nakamura, S; Yamada, T; Yamamoto, T | 1 |
| Antonijevic, M; Canals, M; Hill, R; Hosking, Y; Javitch, JA; Kruegel, AC; Lane, JR; Lemel, L; Mistry, SN; Sanchez, J | 1 |
| Coates, S; Lazarus, P | 1 |
| Dart, RC; Haanschoten, EE; Iwanicki, J; Severtson, SG | 1 |
| Karaskov, T; Koren, G; Moller, M | 1 |
54 review(s) available for oxycodone and morphine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of pain in cancer with systemically administered opioids].
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Administration Schedule; Humans; Infusion Pumps; Methadone; Morphine; Neoplasms; Netherlands; Oxycodone; Pain; Palliative Care; Practice Guidelines as Topic; World Health Organization | 2001 |
Managing postoperative pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Morphine; Nefopam; Oxycodone; Pain, Postoperative; Preanesthetic Medication; Tramadol | 2001 |
The use of oxycodone in cancer-related pain: a literature review.
Topics: Analgesics, Opioid; Drug Administration Schedule; Evidence-Based Medicine; Hallucinations; Humans; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Patient Selection; Research Design; Sample Size; Therapeutic Equivalency; Treatment Outcome | 2001 |
Opioid formulations: tailoring to the needs in chronic pain.
Topics: Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Humans; Morphine; Oxycodone; Pain | 2001 |
Normal-release and controlled-release oxycodone: pharmacokinetics, pharmacodynamics, and controversy.
Topics: Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; Female; Humans; Liver Failure; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care; Sex Factors; Uremia | 2003 |
[Palliative medicine for advanced gynecological malignancy].
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Bone Neoplasms; Drug Therapy, Combination; Female; GABA Agonists; Genital Neoplasms, Female; Humans; Ketamine; Morphine; Muscle Neoplasms; Neoplasm Invasiveness; Nerve Block; Oxycodone; Pain, Intractable; Palliative Care; Peritonitis; Receptors, N-Methyl-D-Aspartate | 2004 |
Advances in opioid therapy and formulations.
Topics: Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Infusion Pumps, Implantable; Male; Morphine; Neoplasms; Oxycodone; Pain Measurement; Pain, Intractable; Risk Assessment; Sensitivity and Specificity; Treatment Outcome | 2005 |
Contribution to variability in response to opioids.
Topics: Analgesics, Opioid; Biological Availability; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fentanyl; Humans; Hydromorphone; Male; Maximum Tolerated Dose; Morphine; Neoplasms; Oxycodone; Pain Measurement; Pain, Intractable; Prognosis; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Interpretation of opioid levels: comparison of levels during chronic pain therapy to levels from forensic autopsies.
Topics: Analgesics, Opioid; Autopsy; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Pain, Intractable | 2005 |
Major increases in opioid analgesic abuse in the United States: concerns and strategies.
Topics: Analgesics, Opioid; Fentanyl; Humans; Hydrocodone; Morphine; Opioid-Related Disorders; Oxycodone; United States | 2006 |
[Basic studies on cancer pain control].
Topics: Analgesics, Opioid; Animals; Constipation; Dose-Response Relationship, Drug; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Vomiting; World Health Organization | 2005 |
The management of pain in children with life-limiting illnesses.
Topics: Analgesics, Opioid; Child; Chronic Disease; Codeine; Fentanyl; Humans; Hydromorphone; Ketamine; Methadone; Morphine; Nociceptors; Oxycodone; Pain; Pain Measurement; Severity of Illness Index | 2007 |
How different is oxycodone from morphine?
Topics: Animals; Biological Transport, Active; Humans; Morphine; Oxycodone; Species Specificity | 2007 |
Effectiveness of opioids in the treatment of chronic non-cancer pain.
Topics: Analgesics, Opioid; Drug Administration Schedule; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Oxymorphone; Pain; Quality of Life; Time Factors; Tramadol | 2008 |
[Differential therapeutic aspects of analgesia with oral sustained-release strong opioids: application intervals, metabolism and immunosuppression].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Evidence-Based Medicine; Female; Humans; Hydromorphone; Immunity, Cellular; Male; Metabolic Clearance Rate; Middle Aged; Morphine; Oxycodone; Pain; Randomized Controlled Trials as Topic | 2008 |
[Difference in tolerance to anti-hyperalgesic effect and its molecular mechanisms between chronic treatment with morphine, fentanyl and oxycodone in a chronic pain-like state].
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Chronic Disease; Disease Models, Animal; Drug Tolerance; Fentanyl; Humans; Mice; Morphine; Oxycodone; Pain; Receptors, Opioid, mu | 2008 |
Oxycodone combinations for pain relief.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Oxycodone; Pain; Pregabalin | 2010 |
Fixed combination of oxycodone with naloxone: a new way to prevent and treat opioid-induced constipation.
Topics: Analgesics, Opioid; Constipation; Drug Combinations; Humans; Laxatives; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Treatment Outcome | 2010 |
Opioid formulations designed to resist/deter abuse.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Combinations; Humans; Morphine; Naltrexone; Niacin; Opioid-Related Disorders; Oxycodone; Pain; United States | 2010 |
[Blood-brain barrier transport of opioid analgesics].
Topics: Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Humans; Mice; Morphine; Morphine Derivatives; Naloxone; Narcotic Antagonists; Organic Cation Transport Proteins; Oxycodone; Pentazocine; Rats | 2011 |
Efficacy and safety of dual-opioid therapy in acute pain.
Topics: Acute Pain; Analgesics, Opioid; Drug Combinations; Drug Synergism; Humans; Morphine; Oxycodone | 2012 |
Likeability and abuse liability of commonly prescribed opioids.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Hydrocodone; Morphine; Opioid-Related Disorders; Oxycodone; Randomized Controlled Trials as Topic | 2012 |
Sequestered naltrexone in sustained release morphine or oxycodone - a way to inhibit illicit use?
Topics: Analgesics, Opioid; Delayed-Action Preparations; Humans; Illicit Drugs; Morphine; Naltrexone; Opioid-Related Disorders; Oxycodone | 2014 |
Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain.
Topics: Analgesics, Opioid; Appetite; Codeine; Consciousness; Fentanyl; Humans; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic; Terminal Care; Thirst | 2014 |
[Long-term opioid therapy in chronic noncancer pain. A systematic review and meta-analysis of efficacy, tolerability and safety in open-label extension trials with study duration of at least 26 weeks].
Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Hydromorphone; Long-Term Care; Morphine; Oxycodone; Oxymorphone; Pain Measurement; Phenols; Randomized Controlled Trials as Topic; Tapentadol; Tramadol; Treatment Outcome | 2015 |
Oxycodone for cancer-related pain.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Administration Schedule; Humans; Morphine; Neoplasms; Oxycodone; Pain; Pain Management; Randomized Controlled Trials as Topic | 2015 |
[New option in the management of cancer pain in Hungary: short acting oral opioid therapy].
Topics: Administration, Oral; Analgesics, Opioid; Analgesics, Short-Acting; Drug Administration Schedule; Drug Approval; Fentanyl; Humans; Hungary; Hydromorphone; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Therapeutic Equivalency; Time Factors | 2015 |
Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations.
Topics: Analgesics, Opioid; Buprenorphine; Chemistry, Pharmaceutical; Humans; Morphine; Oxycodone; Oxymorphone; Pain | 2016 |
Hydromorphone for cancer pain.
Topics: Adult; Analgesics, Opioid; Female; Humans; Hydromorphone; Male; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Randomized Controlled Trials as Topic | 2016 |
Pharmacogenomics and Patient Treatment Parameters to Opioid Treatment in Chronic Pain: A Focus on Morphine, Oxycodone, Tramadol, and Fentanyl.
Topics: Analgesics, Opioid; Chronic Pain; Fentanyl; Humans; Morphine; Oxycodone; Pharmacogenomic Testing; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Tramadol | 2017 |
The Comparative Risk of Delirium with Different Opioids: A Systematic Review.
Topics: Aged; Analgesics, Opioid; Delirium; Humans; Hydromorphone; Meperidine; Morphine; Oxycodone; Pain; Pain Measurement; Risk Factors; Tramadol | 2017 |
Revisiting Oxycodone Analgesia: A Review and Hypothesis.
Topics: Abdominal Pain; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Cancer Pain; Humans; Morphine; Oxycodone; Pain; Pain Measurement | 2017 |
Opioid-Induced Constipation Relief From Fixed-Ratio Combination Prolonged-Release Oxycodone/Naloxone Compared With Oxycodone and Morphine for Chronic Nonmalignant Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Analgesics, Opioid; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Humans; Morphine; Naloxone; Oxycodone; Randomized Controlled Trials as Topic | 2017 |
Oxycodone for cancer-related pain.
Topics: Aged; Analgesics, Opioid; Cancer Pain; Constipation; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Nausea; Neoplasms; Oxycodone; Pain Measurement; Quality of Life; Randomized Controlled Trials as Topic; Sleep Stages; Vomiting | 2017 |
Efficacy and feasibility of opioids for burn analgesia: An evidence-based qualitative review of randomized controlled trials.
Topics: Administration, Cutaneous; Administration, Intranasal; Administration, Mucosal; Administration, Oral; Analgesics, Opioid; Burns; Feasibility Studies; Fentanyl; Humans; Hydromorphone; Morphine; Mouth Mucosa; Oxycodone; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Opioid Rotation in Cancer Pain Treatment.
Topics: Analgesics, Opioid; Buprenorphine; Cancer Pain; Chronic Pain; Fentanyl; Germany; Humans; Hydromorphone; Morphine; Neoplasms; Oxycodone; Pain Management | 2018 |
Comparison of analgesic effect of oxycodone and morphine on patients with moderate and advanced cancer pain: a meta-analysis.
Topics: Analgesics, Opioid; Cancer Pain; Humans; Morphine; Oxycodone; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
[Opioid switch and change of route of administration in cancer patients treated by morphine].
Topics: Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Drug Substitution; Fentanyl; France; Humans; Hydromorphone; Injections, Intravenous; Injections, Subcutaneous; Methadone; Morphine; Oxycodone; Phenols; Tapentadol | 2018 |
Respiratory depression and brain hypoxia induced by opioid drugs: Morphine, oxycodone, heroin, and fentanyl.
Topics: Analgesics, Opioid; Animals; Brain; Fentanyl; Heroin; Humans; Hypoxia, Brain; Morphine; Oxycodone; Rats; Respiratory Insufficiency | 2019 |
[Opioids for Cancer Pain and its Use under Particular Conditions: A Narrative Review].
Topics: Administration, Oral; Analgesics, Opioid; Buprenorphine; Cancer Pain; Codeine; Deglutition Disorders; Fentanyl; Humans; Hydromorphone; Liver Failure; Morphine; Oxycodone; Renal Dialysis; Renal Insufficiency; Tapentadol; Tramadol | 2019 |
Opioids for chronic non-cancer neuropathic pain. An updated systematic review and meta-analysis of efficacy, tolerability and safety in randomized placebo-controlled studies of at least 4 weeks duration.
Topics: Analgesics, Opioid; Chronic Pain; Humans; Morphine; Neuralgia; Oxycodone; Tapentadol | 2020 |
Oxycodone versus morphine for cancer pain titration: A systematic review and pharmacoeconomic evaluation.
Topics: Cancer Pain; Cost-Benefit Analysis; Decision Trees; Delayed-Action Preparations; Economics, Pharmaceutical; Humans; Morphine; Oxycodone; Publication Bias; Risk; Treatment Outcome | 2020 |
Oxycodone versus other opioid analgesics after laparoscopic surgery: a meta-analysis.
Topics: Alfentanil; Analgesics, Opioid; Fentanyl; Humans; Laparoscopy; Morphine; Oxycodone; Pain; Pain Management; Sufentanil | 2021 |
Pharmacogenomics of oxycodone: a narrative literature review.
Topics: Analgesics, Opioid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Humans; Morphine; Oxycodone; Pharmacogenetics; Polymorphism, Genetic | 2021 |
Psychosis after buprenorphine, heroin, methadone, morphine, oxycodone, and tramadol withdrawal: a systematic review.
Topics: Analgesics, Opioid; Buprenorphine; Heroin; Humans; Methadone; Morphine; Oxycodone; Psychotic Disorders; Substance Withdrawal Syndrome; Tramadol | 2021 |
Hydromorphone for cancer pain.
Topics: Adult; Analgesics, Opioid; Cancer Pain; Child; Humans; Hydromorphone; Male; Middle Aged; Morphine; Neoplasms; Oxycodone | 2021 |
Use of opioids in patients with cancer with hepatic impairment-a systematic review.
Topics: Adolescent; Analgesics, Opioid; Cancer Pain; Humans; Morphine; Neoplasms; Oxycodone | 2022 |
Atypical opioids and their effect on respiratory drive.
Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Morphine; Oxycodone | 2021 |
Oxycodone for cancer-related pain.
Topics: Adult; Analgesics, Opioid; Cancer Pain; Constipation; Humans; Morphine; Nausea; Neoplasms; Oxycodone; Pain; Quality of Life; Reproducibility of Results; Sleepiness; Vomiting | 2022 |
Tapentadol for the management of cancer pain in adults: an update.
Topics: Adult; Analgesics; Analgesics, Opioid; Cancer Pain; Humans; Morphine; Multicenter Studies as Topic; Neoplasms; Oxycodone; Pain; Phenols; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Opioid; Tapentadol | 2023 |
Oxycodone: A Current Perspective on Its Pharmacology, Abuse, and Pharmacotherapeutic Developments.
Topics: Analgesics, Opioid; Animals; Humans; Morphine; Opioid-Related Disorders; Oxycodone; Receptors, Opioid; Thebaine | 2023 |
Hydrocodone, Oxycodone, and Morphine Metabolism and Drug-Drug Interactions.
Topics: Analgesics, Opioid; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Hydrocodone; Morphine; Oxycodone; Pain | 2023 |
98 trial(s) available for oxycodone and morphine
| Article | Year |
|---|---|
Analgesic studies of codeine and oxycodone in patients with cancer. II. Comparisons of intramuscular oxycodone with intramuscular morphine and codeine.
Topics: Adult; Aged; Analgesics; Clinical Trials as Topic; Codeine; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain | 1978 |
A two-dose epidural morphine regimen for cesarean section patients: therapeutic efficacy.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Cesarean Section; Female; Humans; Morphine; Nausea; Oxycodone; Pain Measurement; Pain, Postoperative; Pregnancy; Pruritus; Sodium Chloride; Time Factors | 1992 |
Intravenous morphine and oxycodone for pain after abdominal surgery.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Oxycodone; Pain, Postoperative | 1991 |
Morphine and oxycodone in the management of cancer pain: plasma levels determined by chemical and radioreceptor assays.
Topics: Administration, Oral; Analgesia, Patient-Controlled; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Injections, Intravenous; Morphine; Neoplasms; Oxycodone; Pain; Radioligand Assay | 1990 |
Morphine and oxycodone hydrochloride in the management of cancer pain.
Topics: Administration, Oral; Adult; Aged; Codeine; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic | 1990 |
Comparison of different methods of postoperative analgesia after thoracotomy.
Topics: Adult; Analgesia; Bupivacaine; Humans; Injections, Epidural; Morphine; Oxycodone; Pain, Postoperative; Thoracic Surgery; Time Factors | 1986 |
Adverse effects of commonly ordered oral narcotics.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Clinical Trials as Topic; Codeine; Dizziness; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Nausea; Oxycodone; Pentazocine; Sleep Stages | 1981 |
Comparison of intramuscular analgesia, intercostal block, epidural morphine and on-demand-i.v.-fentanyl in the control of pain after upper abdominal surgery.
Topics: Abdomen; Adult; Analgesia; Benzilates; Benzophenones; Bupivacaine; Dipyrone; Drug Combinations; Epidural Space; Female; Fentanyl; Humans; Infusions, Parenteral; Injections; Injections, Intramuscular; Intercostal Muscles; Male; Middle Aged; Morphine; Nerve Block; Oxycodone; Pain, Postoperative; Respiration | 1984 |
Effect of tropisetron, a 5-HT3 receptor antagonist, on analgesia and nausea after intrathecal morphine.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Bupivacaine; Double-Blind Method; Female; Humans; Indoles; Injections, Spinal; Male; Middle Aged; Morphine; Nausea; Oxycodone; Pain Measurement; Pain, Postoperative; Postoperative Complications; Serotonin Antagonists; Tropisetron; Vomiting | 1993 |
Dose-ranging study of oxycodone for chronic pain in advanced cancer.
Topics: Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Prospective Studies | 1993 |
Attenuation of morphine-induced delirium in palliative care by substitution with infusion of oxycodone.
Topics: Aged; Analgesics, Opioid; Delirium; Female; Humans; Male; Morphine; Oxycodone; Palliative Care; Prospective Studies | 1996 |
Comparison of epidural morphine and oxycodone for pain after abdominal surgery.
Topics: Abdomen; Analgesia, Epidural; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Injections, Intravenous; Ketorolac; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Tolmetin | 1997 |
Controlled-release oxycodone and morphine in cancer related pain.
Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain | 1997 |
Comparison of intrathecal morphine and continuous femoral 3-in-1 block for pain after major knee surgery under spinal anaesthesia.
Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Femoral Nerve; Humans; Hydrogen-Ion Concentration; Injections, Spinal; Knee; Male; Morphine; Nerve Block; Oxycodone; Pain Measurement; Premedication; Prospective Studies | 1998 |
Comparison of analgesic efficacy of oxycodone and morphine in postoperative intravenous patient-controlled analgesia.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Humans; Incidence; Injections, Intravenous; Lumbar Vertebrae; Male; Mammaplasty; Middle Aged; Morphine; Morphine Derivatives; Nausea; Oxycodone; Pain Measurement; Pain, Postoperative; Pruritus; Spinal Fusion; Therapeutic Equivalency; Urinary Retention; Vomiting | 1998 |
Randomized, double-blind, cross-over trial comparing safety and efficacy of oral controlled-release oxycodone with controlled-release morphine in patients with cancer pain.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement | 1998 |
Opioid therapy for chronic noncancer back pain. A randomized prospective study.
Topics: Activities of Daily Living; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Mood Disorders; Morphine; Naproxen; Oxycodone; Pain Measurement; Prospective Studies; Sleep; Surveys and Questionnaires; Treatment Outcome | 1998 |
Time course of changes in breathing pattern in morphine- and oxycodone-induced respiratory depression.
Topics: Adult; Analgesics, Opioid; Carbon Dioxide; Cross-Over Studies; Depression, Chemical; Double-Blind Method; Humans; Male; Morphine; Oximetry; Oxycodone; Oxygen; Partial Pressure; Plethysmography; Respiration; Respiratory Insufficiency; Tidal Volume | 1999 |
Relative potency of controlled-release oxycodone and controlled-release morphine in a postoperative pain model.
Topics: Administration, Oral; Adult; Analgesia; Analgesics, Opioid; Analysis of Variance; Double-Blind Method; Female; Humans; Morphine; Oxycodone; Pain, Postoperative | 1999 |
Morphine-induced cardiovascular stimulation: the effects of two doses on healthy subjects.
Topics: Adult; Analgesics, Opioid; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Heart Rate; Histamine; Humans; Male; Morphine; Oxycodone; Oxygen Consumption; Stimulation, Chemical | 2000 |
Morphine or oxycodone in cancer pain?
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Cytochrome P-450 CYP2D6; Debrisoquin; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphinans; Morphine; Morphine Derivatives; Neoplasms; Oxycodone; Pain; Pain Measurement; Phenotype | 2000 |
Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteers.
Topics: Administration, Oral; Adult; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Female; Humans; Lorazepam; Male; Morphine; Narcotics; Oxycodone; Psychomotor Performance; Surveys and Questionnaires | 2003 |
Comparison of sustained-release morphine with sustained-release oxycodone in advanced cancer patients.
Topics: Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Time Factors | 2003 |
Epidural oxycodone or morphine following gynaecological surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, General; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Pruritus | 2004 |
Can coadministration of oxycodone and morphine produce analgesic synergy in humans? An experimental cold pain study.
Topics: Adolescent; Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Humans; Morphine; Oxycodone; Pain | 2004 |
Ventilatory responses of healthy subjects to intravenous combinations of morphine and oxycodone under imposed hypercapnic and hypoxaemic conditions.
Topics: Adolescent; Adult; Analgesics, Opioid; Carbon Dioxide; Cross-Over Studies; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Oxycodone; Oxygen; Respiration | 2005 |
Continuous femoral nerve block versus intra-articular injection for pain control after anterior cruciate ligament reconstruction.
Topics: Administration, Oral; Adolescent; Adult; Amides; Analysis of Variance; Anesthetics, Local; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Arthroscopy; Bone-Patellar Tendon-Bone Grafting; Drug Therapy, Combination; Female; Femoral Nerve; Humans; Hydrocodone; Injections, Intra-Articular; Injections, Intramuscular; Male; Morphine; Narcotics; Nerve Block; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Ropivacaine; Rupture; Treatment Outcome | 2006 |
A comparative study of oxycodone and morphine in a multi-modal, tissue-differentiated experimental pain model.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Dose-Response Relationship, Drug; Electroshock; Esophagus; Female; Hot Temperature; Humans; Male; Models, Neurological; Morphine; Muscle, Skeletal; Nociceptors; Organ Specificity; Oxycodone; Pain; Pain Measurement; Pain Threshold; Pressure; Skin | 2006 |
Oral oxycodone hydrochloride versus epidural anaesthesia for pain control after radical retropubic prostatectomy.
Topics: Acetaminophen; Administration, Oral; Aged; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Drug Therapy, Combination; Early Ambulation; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Prostatectomy; Ropivacaine; Sufentanil | 2006 |
Randomized trial comparing polymer-coated extended-release morphine sulfate to controlled-release oxycodone HCl in moderate to severe nonmalignant pain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Pain Clinics; Pain Measurement; Polymers; Quality of Life; Treatment Outcome | 2006 |
Postoperative pain management after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Craniotomy; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hospital Costs; Humans; Injections, Intravenous; Lactones; Length of Stay; Male; Middle Aged; Morphine; Narcotics; Oxycodone; Pain Measurement; Pain, Postoperative; Single-Blind Method; Sulfones; Treatment Outcome | 2006 |
Methadone in the treatment of pain and terminal delirum in advanced cancer patients.
Topics: Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Neuropsychological Tests; Oxycodone; Pain; Pain Measurement; Palliative Care; Treatment Outcome | 2005 |
Differential effect of opioids in patients with chronic pancreatitis: an experimental pain study.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cross-Over Studies; Denmark; Double-Blind Method; Electric Stimulation; Esophagus; Female; Hot Temperature; Humans; Male; Middle Aged; Morphine; Muscle, Skeletal; Oxycodone; Pain; Pain Measurement; Pain Threshold; Pancreatitis, Chronic; Reproducibility of Results; Skin; Stress, Mechanical; Treatment Outcome | 2007 |
Postoperative intravenous morphine consumption, pain scores, and side effects with perioperative oral controlled-release oxycodone after lumbar discectomy.
Topics: Administration, Oral; Adult; Aged; Delayed-Action Preparations; Diskectomy; Double-Blind Method; Female; Humans; Injections, Intravenous; Lumbar Vertebrae; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Perioperative Care; Prospective Studies | 2007 |
Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteers.
Topics: Administration, Oral; Adult; Affect; Analgesics, Opioid; Attention; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Mental Recall; Morphine; Motivation; Opioid-Related Disorders; Oxycodone; Pain Measurement; Psychomotor Performance; Reaction Time; Risk Factors; Surveys and Questionnaires | 2008 |
Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: an open-label trial.
Topics: Administration, Oral; Aged; Analgesics, Opioid; Constipation; Drug Administration Schedule; Female; Humans; Linear Models; Male; Middle Aged; Morphinans; Morphine; Morphine Derivatives; Nausea; Neoplasms; Oxycodone; Pain; Prospective Studies; Renal Insufficiency, Chronic; Sleep Stages; Treatment Outcome; Vomiting | 2008 |
Efficacy, safety and pharmacokinetic study of a novel fentanyl-containing matrix transdermal patch system in Japanese patients with cancer pain.
Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Endpoint Determination; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement | 2008 |
Pharmacokinetic-pharmacodynamic modeling of morphine and oxycodone concentrations and analgesic effect in a multimodal experimental pain model.
Topics: Administration, Oral; Adult; Algorithms; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electric Stimulation; Female; Hot Temperature; Humans; Infusions, Parenteral; Male; Models, Biological; Morphine; Oxycodone; Pain; Pain Measurement; Pain Threshold; Physical Stimulation | 2008 |
A randomized double-blind crossover comparison of continuous and intermittent subcutaneous administration of opioid for cancer pain.
Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Female; Health Status Indicators; Humans; Hydromorphone; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement | 2008 |
Oral versus intravenous opioid dosing for the initial treatment of acute musculoskeletal pain in the emergency department.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Drug Administration Schedule; Emergency Service, Hospital; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Morphine; Musculoskeletal Diseases; Oxycodone; Pain; Pain Measurement; Prospective Studies; Treatment Outcome; Young Adult | 2008 |
Randomized placebo-controlled trial on local applications of opioids after hemorrhoidectomy.
Topics: Administration, Rectal; Adult; Analgesics, Opioid; Analysis of Variance; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Hemorrhoids; Humans; Immunohistochemistry; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Probability; Prospective Studies; Risk Assessment; Severity of Illness Index; Surgical Procedures, Operative; Treatment Outcome | 2009 |
A randomised comparison of regular oral oxycodone and intrathecal morphine for post-caesarean analgesia.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Anesthesia, Spinal; Area Under Curve; Cesarean Section; Double-Blind Method; Female; Humans; Injections, Spinal; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Pregnancy; Young Adult | 2010 |
A comparison of intravenous oxycodone and intravenous morphine in patient-controlled postoperative analgesia after laparoscopic hysterectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Humans; Hysterectomy; Injections, Intravenous; Laparoscopy; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Sleep; Time Factors | 2009 |
Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Esophagus; Female; Forearm; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Morphine; Muscles; Oxycodone; Pain Measurement; Pain Threshold; Pressure; Skin | 2010 |
Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: abuse potential and relative potencies.
Topics: Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydrocodone; Injections, Intravenous; Male; Morphine; Opioid-Related Disorders; Oxycodone; Pilot Projects; Receptors, Opioid, mu | 2010 |
A comparison of the respiratory effects of oxycodone versus morphine: a randomised, double-blind, placebo-controlled investigation.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, General; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraoperative Complications; Male; Middle Aged; Monitoring, Intraoperative; Morphine; Oxycodone; Pilot Projects; Respiratory Insufficiency; Spirometry; Young Adult | 2010 |
A randomized trial of 2 prescription strategies for opioid treatment of chronic nonmalignant pain.
Topics: Aged; Analgesia; Analgesics, Opioid; Chronic Pain; Codeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrocodone; Male; Middle Aged; Morphine; Musculoskeletal Diseases; Oxycodone; Pain Measurement | 2011 |
Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; Double-Blind Method; Drug Combinations; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Pain Measurement; Patient Satisfaction; Quality of Life; Treatment Outcome | 2012 |
Oral oxycodone offers equivalent analgesia to intravenous patient-controlled analgesia after total hip replacement: a randomized, single-centre, non-blinded, non-inferiority study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Antiemetics; Arthroplasty, Replacement, Hip; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Postoperative Care; Postoperative Nausea and Vomiting; Treatment Outcome | 2011 |
Short-term opioids for breathlessness in stable chronic heart failure: a randomized controlled trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Dyspnea; Female; Heart Failure; Humans; Male; Middle Aged; Morphine; Oxycodone; Severity of Illness Index; Treatment Outcome | 2011 |
How to switch from morphine or oxycodone to methadone in cancer patients? a randomised clinical phase II trial.
Topics: Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Substitution; Female; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Patient Dropouts; Prospective Studies | 2011 |
Prospective randomized observer-blinded study comparing the analgesic efficacy of ultrasound-guided rectus sheath block and local anaesthetic infiltration for umbilical hernia repair.
Topics: Adolescent; Analgesia; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Female; Hernia, Umbilical; Humans; Male; Morphine; Nerve Block; Oxycodone; Pain Measurement; Pain, Postoperative; Prospective Studies; Rectus Abdominis; Treatment Outcome; Ultrasonography, Interventional | 2011 |
Capsaicin instillation for postoperative pain following total knee arthroplasty: a preliminary report of a randomized, double-blind, parallel-group, placebo-controlled, multicentre trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Capsaicin; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Placebos; Range of Motion, Articular; Sensory System Agents; Young Adult | 2011 |
Cannabinoid-opioid interaction in chronic pain.
Topics: Administration, Inhalation; Adult; Analgesics, Opioid; Area Under Curve; Chronic Pain; Delayed-Action Preparations; Dronabinol; Drug Administration Schedule; Drug Synergism; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Treatment Outcome | 2011 |
Continuous wound infusion with ropivacaine fails to provide adequate analgesia after caesarean section.
Topics: Adult; Amides; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Cesarean Section; Double-Blind Method; Female; Finland; Humans; Infusions, Parenteral; Injections, Spinal; Morphine; Oxycodone; Pain Management; Pain Measurement; Pain, Postoperative; Pregnancy; Prospective Studies; Ropivacaine; Sodium Chloride; Treatment Outcome; Young Adult | 2012 |
Serum concentrations of opioids when comparing two switching strategies to methadone for cancer pain.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Neoplasms; Oxycodone; Pain; Palliative Care; Patient Dropouts | 2012 |
Local infiltration analgesia with levobupivacaine compared with intrathecal morphine in total hip arthroplasty patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Local; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Early Ambulation; Female; Follow-Up Studies; Humans; Injections, Spinal; Levobupivacaine; Male; Middle Aged; Morphine; Nerve Block; Oxycodone; Oxygen; Pain Management; Pain Measurement; Pain, Postoperative; Patient Discharge; Patient Satisfaction; Postoperative Nausea and Vomiting; Single-Blind Method | 2012 |
[A pilot study of the reduced effects of adverse events caused by oral morphine and oxycodone after rotating to fentanyl patch in patients with metastatic breast cancer].
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Breast Neoplasms; Drug Therapy, Combination; Female; Fentanyl; Humans; Middle Aged; Morphine; Neoplasm Metastasis; Oxycodone; Pain; Pilot Projects; Prospective Studies; Transdermal Patch | 2012 |
Analgesic efficacy and tolerability of intravenous morphine versus combined intravenous morphine and oxycodone in a 2-center, randomized, double-blind, pilot trial of patients with moderate to severe pain after total hip replacement.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Chi-Square Distribution; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Germany; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Pilot Projects; Time Factors; Treatment Outcome | 2012 |
Effectiveness of multimodal pain management after bipolar hemiarthroplasty for hip fracture: a randomized, controlled study.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cefmetazole; Celecoxib; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Epinephrine; Female; Fentanyl; Hip Fractures; Humans; Injections, Intra-Articular; Ketorolac; Male; Morphine; Oxycodone; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Pyrazoles; Ropivacaine; Single-Blind Method; Statistics, Nonparametric; Sulfonamides; Treatment Outcome | 2013 |
Repeat dose opioids may be effective for breathlessness in chronic heart failure if given for long enough.
Topics: Aged; Analgesics, Opioid; Analysis of Variance; Chronic Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Dyspnea; Female; Heart Failure; Humans; Male; Morphine; Oxycodone; Placebos; Principal Component Analysis; Severity of Illness Index; Treatment Outcome | 2013 |
Tapentadol prolonged release versus strong opioids for severe, chronic low back pain: results of an open-label, phase 3b study.
Topics: Adult; Aged; Analgesics, Opioid; Buprenorphine; Chronic Pain; Constipation; Delayed-Action Preparations; Female; Fentanyl; Humans; Hydromorphone; Low Back Pain; Male; Middle Aged; Morphine; Neuralgia; Oxycodone; Pain Measurement; Phenols; Severity of Illness Index; Tapentadol | 2013 |
Comparison of the efficacy and safety of dual-opioid treatment with morphine plus oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after total knee arthroplasty.
Topics: Acetaminophen; Aged; Algorithms; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain, Postoperative; Severity of Illness Index | 2013 |
A phase 3, randomized, double-blind comparison of analgesic efficacy and tolerability of Q8003 vs oxycodone or morphine for moderate-to-severe postoperative pain following bunionectomy surgery.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Endpoint Determination; Ethnicity; Female; Hallux Valgus; Humans; Ibuprofen; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Young Adult | 2013 |
Morphine versus oxycodone analgesia after percutaneous kidney stone surgery: a randomised double blinded study.
Topics: Adult; Aged; Analgesics, Opioid; Double-Blind Method; Female; Humans; Kidney Calculi; Male; Middle Aged; Morphine; Nephrostomy, Percutaneous; Oxycodone; Pain Measurement; Pain, Postoperative; Visceral Pain | 2013 |
Comparison of a drug versus money and drug versus drug self-administration choice procedure with oxycodone and morphine in opioid addicts.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Buprenorphine; Choice Behavior; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Male; Middle Aged; Morphine; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Pain Measurement; Pupil; Reward; Self Administration; Surveys and Questionnaires; Time Factors; Token Economy; Young Adult | 2013 |
A multimodal approach for postoperative pain management after lumbar decompression surgery: a prospective, randomized study.
Topics: Aged; Aged, 80 and over; Analgesics; Celecoxib; Decompression, Surgical; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Pregabalin; Prospective Studies; Pyrazoles; Sulfonamides; Treatment Outcome | 2013 |
Oral oxycodone plus intravenous acetaminophen versus intravenous morphine sulfate in acute bone fracture pain control: a double-blind placebo-controlled randomized clinical trial.
Topics: Acetaminophen; Acute Disease; Administration, Intravenous; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; Female; Fractures, Bone; Humans; Male; Morphine; Nausea; Oxycodone; Pain; Pain Measurement; Pruritus; Young Adult | 2014 |
A randomised trial of oral versus intravenous opioids for treatment of pain after cardiac surgery.
Topics: Administration, Intravenous; Administration, Oral; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cardiac Surgical Procedures; Drug Combinations; Female; Humans; Male; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain, Postoperative | 2014 |
Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS).
Topics: Analgesics, Opioid; Cohort Studies; Europe; Female; Fentanyl; Genetic Association Studies; Genetic Variation; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Treatment Outcome | 2012 |
Effects of immediate-release opioid on memory functioning: a randomized-controlled study in patients receiving sustained-release opioids.
Topics: Affect; Aged; Analgesics, Opioid; Breakthrough Pain; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Memory; Mental Recall; Middle Aged; Morphine; Neoplasms; Neuropsychological Tests; Oxycodone; Pain | 2014 |
Morphine or oxycodone for cancer-related pain? A randomized, open-label, controlled trial.
Topics: Analgesics, Opioid; Cross-Over Studies; Drug Substitution; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Prospective Studies; Treatment Outcome | 2015 |
A randomized, double-blind, placebo-controlled study of preemptive oral oxycodone with morphine patient-controlled anesthesia for postoperative pain management in patients undergoing uterine artery embolization for symptomatic uterine fibroids.
Topics: Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Humans; Leiomyoma; Morphine; Oxycodone; Pain, Postoperative; Prospective Studies; Treatment Outcome; Uterine Artery Embolization | 2014 |
Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Mandibular Advancement; Maxilla; Middle Aged; Morphine; Narcotics; Oxycodone; Pain Measurement; Pain, Postoperative; Placebos; Pregabalin; Premedication; Prospective Studies; Pyrazoles; Sleep Apnea, Obstructive; Sulfonamides; Treatment Outcome; Visual Analog Scale; Young Adult | 2014 |
Safety and efficacy of oxycodone/naloxone vs. oxycodone vs. morphine for the treatment of chronic low back pain: results of a 12 week prospective, randomized, open-label blinded endpoint streamlined study with prolonged-release preparations.
Topics: Adult; Aged; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Germany; Humans; Low Back Pain; Male; Middle Aged; Morphine; Naloxone; Oxycodone; Prospective Studies; Young Adult | 2015 |
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Drug-Related Side Effects and Adverse Reactions; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone | 2016 |
A Randomized Controlled Trial Comparing Adductor Canal Catheter and Intraarticular Catheter After Primary Total Knee Arthroplasty.
Topics: Aged; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Catheters; Female; Humans; Length of Stay; Male; Middle Aged; Morphine; Nerve Block; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Peripheral Nerves; Prospective Studies; Treatment Outcome | 2016 |
Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) versus Extended-Release Morphine Administered Orally in Nondependent Recreational Opioid Users.
Topics: Adult; Analgesics, Opioid; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Humans; Illicit Drugs; Male; Morphine; Opioid-Related Disorders; Oxycodone; Pennsylvania; Placebo Effect; Prevalence; Risk Factors; Substance-Related Disorders; Treatment Outcome; Young Adult | 2017 |
Comparison of the Tolerability Profile of Controlled-Release Oral Morphine and Oxycodone for Cancer Pain Treatment. An Open-Label Randomized Controlled Trial.
Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Delayed-Action Preparations; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Palliative Care; Risk; Treatment Outcome | 2016 |
Controlled-release oxycodone improves pain management after uterine artery embolisation for symptomatic fibroids.
Topics: Adult; Analgesics, Opioid; Female; Humans; Leiomyoma; Length of Stay; Morphine; Oxycodone; Pain, Postoperative; Prospective Studies; Treatment Outcome; Uterine Artery Embolization; Uterine Neoplasms | 2017 |
Effects of Ibudilast on the Subjective, Reinforcing, and Analgesic Effects of Oxycodone in Recently Detoxified Adults with Opioid Dependence.
Topics: Analgesics, Opioid; Craving; Heroin; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Phosphodiesterase Inhibitors; Pyridines | 2017 |
Effects of oxycodone on immune function in patients undergoing radical resection of rectal cancer under general anesthesia.
Topics: Analgesics, Opioid; Anesthesia, General; Biomarkers; Female; Humans; Immunologic Factors; Male; Middle Aged; Morphine; Oxycodone; Rectal Neoplasms; Treatment Outcome | 2017 |
A comparison of oral controlled-release morphine and oxycodone with transdermal formulations of buprenorphine and fentanyl in the treatment of severe pain in cancer patients.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Cancer Pain; Constipation; Delayed-Action Preparations; Drug Therapy, Combination; Fentanyl; Humans; Lactulose; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Severity of Illness Index | 2017 |
Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study).
Topics: Analgesics, Opioid; Biomarkers, Tumor; Cancer Pain; Catechol O-Methyltransferase; Female; Humans; Male; Morphine; Neoplasms; Oxycodone; Pain Management; Polymorphism, Single Nucleotide | 2017 |
Oral prolonged-release oxycodone/naloxone offers equivalent analgesia to intravenous morphine patient-controlled analgesia after total knee replacement. A randomized controlled trial.
Topics: Administration, Oral; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Delayed-Action Preparations; Drug Combinations; Female; Humans; Infusions, Intravenous; Male; Morphine; Naloxone; Oxycodone; Pain, Postoperative; Prospective Studies | 2018 |
Intravenous Oxycodone versus Intravenous Morphine in Cancer Pain: A Randomized, Open-Label, Parallel-Group, Active-Control Study.
Topics: Administration, Intravenous; Adult; Age Distribution; Aged; Analgesics, Opioid; Cancer Pain; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Patient Satisfaction; Republic of Korea; Retrospective Studies; Young Adult | 2017 |
Oral oxycodone for pain after caesarean section: A randomized comparison with nurse-administered IV morphine in a pragmatic study.
Topics: Administration, Intravenous; Administration, Oral; Adult; Analgesics, Opioid; Cesarean Section; Elective Surgical Procedures; Female; Follow-Up Studies; Humans; Infant, Newborn; Morphine; Nurses; Oxycodone; Pain Measurement; Pain, Postoperative; Treatment Outcome; Young Adult | 2015 |
The James A. Rand Young Investigator's Award: Large Opioid Prescriptions Are Unnecessary After Total Joint Arthroplasty: A Randomized Controlled Trial.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Drug Prescriptions; Female; Humans; Length of Stay; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Patient Reported Outcome Measures; Postoperative Period; Practice Patterns, Physicians'; Regression Analysis; Treatment Outcome | 2019 |
Efficacy and safety of sustained-release oxycodone compared with immediate-release morphine for pain titration in cancer patients: A multicenter, open-label, randomized controlled trial (SOCIAL).
Topics: Aged; Cancer Pain; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Measurement; Treatment Outcome | 2019 |
Comparison of the Quality of Life of Cancer Patients with Pain Treated with Oral Controlled-Release Morphine and Oxycodone and Transdermal Buprenorphine and Fentanyl.
Topics: Analgesics, Opioid; Buprenorphine; Cancer Pain; Delayed-Action Preparations; Female; Fentanyl; Humans; Male; Morphine; Neoplasms; Oxycodone; Quality of Life | 2019 |
A randomized pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling during surgery.
Topics: Adult; Analgesics, Opioid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Gene Expression; Gene Expression Profiling; Humans; Killer Cells, Natural; Laparotomy; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Pilot Projects; Treatment Outcome | 2019 |
Post-operative opioid-related adverse events with intravenous oxycodone compared to morphine: A randomized controlled trial.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Humans; Morphine; Oxycodone; Pain, Postoperative | 2021 |
A 12-hour rapid titration method for cancer pain: a randomized, controlled, open-label study.
Topics: Analgesics, Opioid; Cancer Pain; Humans; Morphine; Neoplasms; Oxycodone; Quality of Life | 2021 |
Oxycodone versus morphine for analgesia after laparoscopic endometriosis resection.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Endometriosis; Female; Humans; Laparoscopy; Morphine; Oxycodone; Pain, Postoperative; Prospective Studies; Time Factors | 2021 |
Gabapentin and intrathecal morphine combination therapy results in decreased oral narcotic use and more consistent pain scores after posterior spinal fusion for adolescent idiopathic scoliosis.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Gabapentin; Humans; Kyphosis; Morphine; Narcotics; Nausea; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Pruritus; Retrospective Studies; Scoliosis; Spinal Fusion; Vomiting | 2021 |
Opioid-sparing pain management protocol after shoulder arthroplasty results in less opioid consumption and higher satisfaction: a prospective, randomized controlled trial.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Bupivacaine; Celecoxib; Gabapentin; Humans; Ketorolac; Morphine; Oxycodone; Pain Management; Pain, Postoperative; Prospective Studies; Randomized Controlled Trials as Topic | 2022 |
Efficacy of Opioids in Preemptive Multimodal Analgesia for Total Knee Arthroplasty: A Prospective, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Double-Blind Method; Humans; Morphine; Oxycodone; Pain, Postoperative; Pregabalin; Prospective Studies | 2023 |
Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study).
Topics: Analgesics, Opioid; Biomarkers; Cancer Pain; Catechol O-Methyltransferase; Genotype; Humans; Morphine; Neoplasms; Oxycodone; Pain | 2023 |
333 other study(ies) available for oxycodone and morphine
| Article | Year |
|---|---|
Analgesic narcotic antagonists. 8. 7 alpha-Alkyl-4,5 alpha-epoxymorphinan-6-ones.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Hydrocodone; In Vitro Techniques; Mice; Narcotic Antagonists; Rats; Reaction Time | 1981 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Effect of a 6-cyano substituent in 14-oxygenated N-methylmorphinans on opioid receptor binding and antinociceptive potency.
Topics: Analgesics; Animals; Brain; In Vitro Techniques; Mice; Mice, Inbred ICR; Morphinans; Nitriles; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Morphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors.
Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Guinea Pigs; Isoquinolines; Models, Molecular; Morphinans; Rats; Receptors, Opioid | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Access to 7β-analogs of codeine with mixed μ/δ agonist activity via 6,7-α-epoxide opening.
Topics: Animals; Codeine; Epoxy Compounds; Humans; Mice; Models, Molecular; Morphinans; Receptors, Opioid, delta; Receptors, Opioid, mu | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalins; Indoles; Mice; Molecular Structure; Naphthalenes; Oxycodone; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, mu; Structure-Activity Relationship | 2019 |
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation | 2019 |
Analgesic drugs in the management of pain.
Topics: Analgesics; Anti-Anxiety Agents; Aspirin; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Methadone; Morphine; Oxycodone; Pain; Pain, Intractable; Pentazocine; Pyrazoles | 1977 |
Canadian government study shows big rise in Canadian use of several narcotics.
Topics: Canada; Codeine; Drug Utilization; Humans; Hydrocodone; Meperidine; Morphine; Narcotics; Oxycodone | 1979 |
[Role of the humoral factor in the mechanism of analgetic effect of acupuncture].
Topics: Acupuncture Therapy; Analgesia; Analgesics; Animals; Endorphins; Humans; Morphine; Nociceptors; Oxycodone; Rabbits; Serotonin | 1977 |
Antinociceptive effects and central nervous system depression caused by oxycodone and morphine in rats.
Topics: Analgesics; Animals; Central Nervous System; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Injections, Spinal; Injections, Subcutaneous; Morphine; Oxycodone; Rats; Rats, Inbred Strains | 1992 |
Histamine release induced by opioid analgesics: a comparative study using porcine mast cells.
Topics: Analgesics, Opioid; Animals; Histamine Release; Hydromorphone; Kidney; Liver; Lung; Mast Cells; Meperidine; Methadone; Morphine; Myocardium; Oxycodone; Swine | 1991 |
Pain during burn dressing change in children: relationship to burn area, depth and analgesic regimens.
Topics: Acetaminophen; Adolescent; Bandages; Burns; Child; Female; Humans; Male; Morphine; Oxycodone; Pain; Pain Measurement | 1991 |
Sublingual absorption of selected opioid analgesics.
Topics: Administration, Sublingual; Adult; Analgesics, Opioid; Analysis of Variance; Biological Availability; Buprenorphine; Fentanyl; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Morphine; Mouth; Naloxone; Oxycodone; Time Factors | 1988 |
Hallucinations during morphine but not during oxycodone treatment.
Topics: Adult; Codeine; Hallucinations; Humans; Morphine; Oxycodone | 1988 |
Relationships between immunogen structure and antisera specificity in the narcotic alkaloid series.
Topics: Adult; Animals; Antibody Specificity; Codeine; Dogs; Ethylmorphine; Female; Humans; Male; Milk, Human; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Rabbits; Radioimmunoassay | 1981 |
Facilitation of thin-layer chromatographic identification of opiates by derivatization with acetic anhydride or methoxyamine.
Topics: Acetic Anhydrides; Chromatography, Thin Layer; Codeine; Humans; Hydrocodone; Hydromorphone; Hydroxylamines; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone | 1995 |
The effect of intrinsic efficacy on opioid tolerance.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Fentanyl; Male; Meperidine; Mice; Morphine; Narcotics; Oxycodone | 1995 |
The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model.
Topics: Analgesia; Animals; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Mixed Function Oxygenases; Morphine; Oxycodone; Oxymorphone; Quinine; Rats; Rats, Sprague-Dawley | 1994 |
Switching to a longer-acting opioid.
Topics: Breast Neoplasms; Delayed-Action Preparations; Female; Humans; Middle Aged; Morphine; Oxycodone; Pain; Therapeutic Equivalency | 1994 |
The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats.
Topics: Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Morphinans; Morphine; Naloxone; Nociceptors; Oxycodone; Rats; Rats, Sprague-Dawley | 1994 |
Determination of the serum protein binding of oxycodone and morphine using ultrafiltration.
Topics: Adsorption; Adult; Blood Proteins; Body Temperature; Female; Humans; Hydrogen-Ion Concentration; Male; Morphine; Orosomucoid; Oxycodone; Protein Binding; Serum Albumin; Ultrafiltration | 1993 |
Evaluation of recalcitrant pain in HIV-infected hospitalized patients.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Female; Fentanyl; HIV Infections; Hospitalization; Humans; Infant; Male; Morphine; Oxycodone; Pain; Substance Abuse, Intravenous | 1994 |
Antinociceptive and immunosuppressive effects of opiate drugs: a structure-related activity study.
Topics: Animals; Cell Division; Codeine; Hydromorphone; Immune System; Immunosuppression Therapy; Interleukin-2; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Oxycodone; Structure-Activity Relationship | 1997 |
Opioid substitution to reduce adverse effects in cancer pain management.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hospice Care; Humans; Male; Medical Audit; Methadone; Middle Aged; Morphine; Nausea; Neoplasms; Oxycodone; Pain; Pain Measurement; Prospective Studies; Sleep Stages; Sufentanil; Vomiting | 1999 |
Efficacy of controlled-release oxycodone.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Humans; Morphine; Oxycodone | 1999 |
The relative potency between high dose oral oxycodone and intravenous morphine: a case illustration.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Morphine; Oxycodone; Treatment Outcome | 1999 |
Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Nociceptors; Oxycodone; Rats; Rats, Sprague-Dawley | 2000 |
Distinction among eight opiate drugs in urine by gas chromatography-mass spectrometry.
Topics: Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Molecular Structure; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Oxymorphone | 1999 |
Trends in medical use and abuse of opioid analgesics.
Topics: Analgesics, Opioid; Drug Utilization; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Retrospective Studies; Risk Assessment; Social Change; United States | 2000 |
A sensitive solid-phase fluoroimmunoassay for detection of opiates in urine.
Topics: Antibodies, Monoclonal; Autoanalysis; Binding, Competitive; Codeine; Fluorescein; Fluoroimmunoassay; Humans; Microspheres; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Sensitivity and Specificity | 2000 |
Re: The relative potentcy between high-dose oral oxycodone and intravenous morphine.
Topics: Administration, Oral; Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Injections, Intravenous; Morphine; Oxycodone; Palliative Care | 2000 |
Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat.
Topics: Analgesics, Opioid; Animals; Benzomorphans; Drug Tolerance; Male; Morphine; Oxycodone; Rats | 2000 |
[Opioids. Pharmacology, clinic, prospectives for an extensive use].
Topics: Analgesics, Opioid; Codeine; Drug Tolerance; Fentanyl; Humans; Hydromorphone; Methadone; Morphine; Oxycodone; Receptors, Opioid; Tramadol | 2000 |
Morphine and alternative opioids in cancer pain: the EAPC recommendations.
Topics: Administration, Oral; Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Administration Schedule; Fentanyl; Humans; Hydromorphone; Infusions, Intravenous; Injections, Spinal; Injections, Subcutaneous; Methadone; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care | 2001 |
Opioid therapy for chronic painful conditions.
Topics: Analgesics, Opioid; Chronic Disease; Clinical Trials as Topic; Fentanyl; Humans; Karnofsky Performance Status; Low Back Pain; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Patient Selection; Practice Guidelines as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors | 2001 |
The simultaneous determination of codeine, morphine, hydrocodone, hydromorphone, 6-acetylmorphine, and oxycodone in hair and oral fluid.
Topics: Codeine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Reproducibility of Results; Saliva; Substance Abuse Detection | 2002 |
Oral oxycodone: new preparation. No better than oral morphine.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; France; Humans; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
The terminal cancer patient: effects of age, gender, and primary tumor site on opioid dose.
Topics: Age Factors; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Narcotics; Neoplasms; Oxycodone; Pain; Retrospective Studies; Sex Factors; Terminal Care | 2003 |
[Antagonism of N-allylnormorphine to morphine and eucodal on blood circulation of unanesthetized dogs].
Topics: Animals; Blood Circulation; Codeine; Dogs; Morphine; Morphine Derivatives; Nalorphine; Oxycodone | 1955 |
The addiction potential of oxycodone (Percodan).
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Behavior, Addictive; Caffeine; California; Drug Combinations; Humans; Morphine; Oxycodone; Phenacetin | 1963 |
DERIVATIVES OF MORPHINE. 3. SULFUR ANALOGS OF 14-HYDROXYDIHYDROCODEINONE.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chemistry, Pharmaceutical; Morphine; Oxycodone; Pharmacology; Research; Sulfur | 1964 |
THE RELATIONSHIP BETWEEN ANALGESIC ACTIVITY, ACUTE TOXICITY AND CHEMICAL STRUCTURE INESTERS OF 14-HYDROXYCODEINONE.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chemistry, Pharmaceutical; Codeine; Mice; Morphine; Oxycodone; Pharmacology; Research; Respiratory Insufficiency; Seizures; Toxicology | 1964 |
Therapy switching in patients receiving long-acting opioids.
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Comorbidity; Delayed-Action Preparations; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain | 2004 |
[Use of opioids against severe cancer pain].
Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care | 2004 |
Incidence of constipation associated with long-acting opioid therapy: a comparative study.
Topics: Aged; Analgesics, Opioid; California; Constipation; Female; Fentanyl; Humans; Incidence; Male; Middle Aged; Morphine; Oxycodone; Pain; Retrospective Studies | 2004 |
Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Macaca mulatta; Male; Mice; Mice, Inbred ICR; Morphine; Narcotics; Nociceptors; Oxycodone; Pain Measurement; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 2004 |
[Increasing importance of opioids in geriatrics].
Topics: Aged; Analgesics, Opioid; Costs and Cost Analysis; Drug Prescriptions; Fentanyl; Geriatrics; Germany; Humans; Morphine; Naloxone; Oxycodone; Tramadol | 2005 |
Nociceptive sensitivity and opioid antinociception and antihyperalgesia in Freund's adjuvant-induced arthritic male and female rats.
Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Body Weight; Butorphanol; Dose-Response Relationship, Drug; Estrous Cycle; Female; Foot; Freund's Adjuvant; Hyperalgesia; Loperamide; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Oxycodone; Pain Measurement; Pressure; Rats; Rats, Inbred Lew; Sex Characteristics | 2005 |
Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Morphinans; Morphine; Morphine Derivatives; Oxycodone; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
[Parenteral opioids in end-of-life care in cancer patients].
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Delayed-Action Preparations; Drug Administration Schedule; Fentanyl; Guideline Adherence; Humans; Infusions, Parenteral; Injections, Intravenous; Morphine; Neoplasms; Oxycodone; Pain, Intractable; Palliative Care; Quality of Life; Suppositories | 2005 |
Postoperative analgesic requirements - total laparoscopic hysterectomy versus vaginal hysterectomy.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hysterectomy; Hysterectomy, Vaginal; Laparoscopy; Middle Aged; Morphine; Oxycodone; Pain, Postoperative; Retrospective Studies; Time Factors; Tramadol | 2005 |
Co-administration of oxycodone and morphine and analgesic synergy re-examined.
Topics: Analgesics, Opioid; Cold Temperature; Drug Combinations; Drug Synergism; Humans; Morphine; Nociceptors; Oxycodone; Pain | 2005 |
Suppression of thyrotropin by morphine in a severely stressed patient.
Topics: Back Pain; Female; Humans; Hypothyroidism; Intervertebral Disc Displacement; Kidney Failure, Chronic; Middle Aged; Morphine; Oxycodone; Renal Dialysis; Stress, Physiological; Thyrotropin; Thyroxine; Triiodothyronine | 2005 |
Sick sisters.
Topics: Analgesics, Opioid; Central Nervous System Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Miosis; Morphine; Naloxone; Oxycodone; Poisoning; Respiratory Insufficiency; Siblings; Treatment Outcome | 2005 |
No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Analysis of Variance; Decision Making; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Predictive Value of Tests; Prospective Studies; Treatment Outcome | 2006 |
Preoperative "fentanyl challenge" as a tool to estimate postoperative opioid dosing in chronic opioid-consuming patients.
Topics: Analgesics, Opioid; Blood Gas Analysis; Computer Simulation; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hydrocodone; Infusions, Intravenous; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Preoperative Care; Prospective Studies; Spinal Fusion | 2005 |
Opioid switch in palliative care, opioid choice by clinical need and opioid availability.
Topics: Aged; Ambulatory Care Facilities; Analgesics, Opioid; Buprenorphine; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization Review; Female; Fentanyl; Hospitals; Humans; Hydromorphone; Male; Middle Aged; Morphine; Oxycodone; Pain; Palliative Care; Prospective Studies; Treatment Outcome | 2005 |
Antinociceptive effect of oxycodone in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Time Factors | 2005 |
The effect of FDA approval of a generic competitor to OxyContin (oxycodone HCl controlled-release) tablets on the abuse of oxycodone.
Topics: Analgesics, Opioid; Catchment Area, Health; Delayed-Action Preparations; Drug Approval; Drug Prescriptions; Drugs, Generic; Humans; Hydrocodone; Methadone; Morphine; Oxycodone; Poison Control Centers; Population Surveillance; Prevalence; Substance-Related Disorders; United States; United States Food and Drug Administration | 2006 |
[Efficacy of controlled-release oxycodone for dyspnea in cancer patients--three case series].
Topics: Administration, Oral; Aged; Analgesics, Opioid; Delayed-Action Preparations; Dyspnea; Female; Humans; Injections, Subcutaneous; Lung Neoplasms; Male; Middle Aged; Morphine; Oxycodone | 2006 |
Morphine, oxycodone, methadone and its enantiomers in different models of nociception in the rat.
Topics: Acute Disease; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Male; Methadone; Morphine; Neuralgia; Oxycodone; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Spinal Nerves | 2006 |
Clinical considerations in the treatment of chronic pain with opiates.
Topics: Accidents, Traffic; Alcoholism; Analgesics, Opioid; Chronic Disease; Depression; Humans; Low Back Pain; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain | 2006 |
Economic evaluation of Durogesic in moderate to severe, nonmalignant, chronic pain in Germany.
Topics: Administration, Cutaneous; Analgesics, Opioid; Buprenorphine; Chronic Disease; Cost-Benefit Analysis; Delayed-Action Preparations; Fentanyl; Germany; Health Services; Humans; Morphine; Oxycodone; Pain; Quality-Adjusted Life Years | 2006 |
Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.
Topics: Algorithms; Analgesics, Opioid; Animals; Area Under Curve; Autoradiography; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intravenous; Injections, Spinal; Male; Morphinans; Morphine; Motor Activity; Oxycodone; Oxymorphone; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction | 2006 |
Trends and geographic variation of opiate medication use in state Medicaid fee-for-service programs, 1996 to 2002.
Topics: Analgesics, Opioid; Data Interpretation, Statistical; Drug Prescriptions; Drug Utilization; Fee-for-Service Plans; Humans; Hydrocodone; Medicaid; Methadone; Models, Theoretical; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; United States | 2006 |
Medicating "Margaret".
Topics: Advance Directives; Alzheimer Disease; Analgesics, Opioid; Antipsychotic Agents; Electroconvulsive Therapy; Female; Fentanyl; Hospice Care; Humans; Lorazepam; Methadone; Middle Aged; Morphine; Oxycodone; Pain; Palliative Care; Psychomotor Agitation; Right to Die | 2006 |
Opioid agonist efficacy predicts the magnitude of tolerance and the regulation of mu-opioid receptors and dynamin-2.
Topics: Alkylation; Analgesics, Opioid; Animals; Binding, Competitive; Cinnamates; Dose-Response Relationship, Drug; Down-Regulation; Drug Tolerance; Dynamin II; Etorphine; Male; Mice; Morphine; Morphine Derivatives; Narcotic Antagonists; Oxycodone; Pain Measurement; Pain Threshold; Predictive Value of Tests; Protein Processing, Post-Translational; Reaction Time; Receptors, Opioid, mu; Spinal Cord | 2007 |
Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Guinea Pigs; Male; Morphine; Neuralgia; Oxycodone; Pain; Pain Measurement; Radioligand Assay; Rats; Rats, Sprague-Dawley | 2007 |
Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opiates.
Topics: Analgesics, Opioid; Animals; Brain; Brain Stem; Buprenorphine; Carbon Radioisotopes; Cerebellum; Competitive Bidding; Diprenorphine; Limbic System; Male; Morphine; Narcotic Antagonists; Oxycodone; Positron-Emission Tomography; Prosencephalon; Quinine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reproducibility of Results; Tissue Distribution | 2007 |
Comment and reply on: Randomized trial comparing polymer-coated extended-release morphine sulfate to controlled-release oxycodone HCl in moderate to severe nonmalignant pain.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Humans; Morphine; Oxycodone; Pain; Polymers; Randomized Controlled Trials as Topic | 2007 |
Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine.
Topics: Animals; Central Nervous System; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Inflammation; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Narcotic Antagonists; Narcotics; Oxycodone; Pain Measurement; Protein Binding; Sciatica; Sulfur Isotopes | 2008 |
Prescribing patterns and purchasing costs of long-acting opioids over nine years at an academic oncology hospital.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Costs; Drug Utilization; Fentanyl; Humans; Methadone; Morphine; Oxycodone; Time Factors | 2007 |
[Feasibility to treat pediatric cancer pain with analgesics for adults and their efficacy].
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Constipation; Delayed-Action Preparations; Feasibility Studies; Female; Fentanyl; Humans; Leukemia; Lymphoma; Male; Morphine; Nausea; Oxycodone; Pain, Intractable; Vomiting; World Health Organization | 2007 |
Opioid analgesics for cancer pain: symptom control for the living or comfort for the dying? A qualitative study to investigate the factors influencing the decision to accept morphine for pain caused by cancer.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Attitude to Death; Codeine; Decision Making; Drug Combinations; Fear; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Palliative Care; Patient Acceptance of Health Care; Patients; Physician-Patient Relations; Randomized Controlled Trials as Topic; Terminal Care | 2008 |
Abuse deterrence focus of upcoming opioid formulations.
Topics: Analgesics, Opioid; Chemistry, Pharmaceutical; Humans; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Technology, Pharmaceutical | 2008 |
Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice.
Topics: Analgesics, Opioid; Animals; Codeine; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Hot Temperature; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Quinidine; Reserpine; Seizures; Stereoisomerism; Tramadol | 2008 |
Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Male; Morphine; Oxycodone; Pain Measurement; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2008 |
Re: Benchmarking the use of opioids.
Topics: Analgesics, Opioid; Drug Prescriptions; Hospital Mortality; Humans; Morphine; Oxycodone; Terminal Care | 2008 |
The epidemiologic association between opioid prescribing, non-medical use, and emergency department visits.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Health Surveys; Humans; Hydrocodone; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Statistics as Topic; United States; Utilization Review | 2008 |
Differential activation and trafficking of micro-opioid receptors in brain slices.
Topics: Analgesics, Opioid; Animals; Brain; Chelating Agents; Egtazic Acid; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fluorescent Antibody Technique, Direct; Locus Coeruleus; Methadone; Mice; Mice, Knockout; Mice, Transgenic; Morphine; Neurons; Oxycodone; Oxymorphone; Protein Transport; Radioligand Assay; Receptors, Opioid, mu; Recombinant Fusion Proteins; Time Factors | 2008 |
Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines.
Topics: Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Azabicyclo Compounds; Benzodiazepines; Citalopram; Depression; Drug Overdose; Electrocardiography; Heart Rate; Humans; Hypnotics and Sedatives; Male; Middle Aged; Morphine; Narcotics; Oxycodone; Piperazines; Sleep Initiation and Maintenance Disorders; Suicide, Attempted | 2008 |
When pharmacology and psychology do not mix.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Drug Administration Schedule; Drug Synergism; Female; Humans; Morphine; Oxycodone; Respiratory Insufficiency; Treatment Outcome | 2008 |
Oxycodone-induced analgesic effects in a bone cancer pain model in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Disease Models, Animal; Fentanyl; Luciferases; Male; Mice; Mice, Inbred C3H; Morphine; Neoplasms, Experimental; Osteolysis; Oxycodone; Pain | 2008 |
The underrecognized toll of prescription opioid abuse on young children.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Buprenorphine; Child, Preschool; Female; Humans; Hydrocodone; Hydromorphone; Infant; Infant, Newborn; Male; Methadone; Morphine; Oxycodone; Poisoning; Prescription Drugs; United States | 2009 |
An audit of analgesia requirements for high-dose-rate prostate brachytherapy.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Brachytherapy; Butylscopolammonium Bromide; Humans; Male; Medical Audit; Middle Aged; Morphine; Muscarinic Antagonists; Oxycodone; Parasympatholytics; Postoperative Care; Prostatic Neoplasms; Radiotherapy Dosage; Retrospective Studies | 2008 |
Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast).
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Brain; Bronchodilator Agents; Dose-Response Relationship, Drug; Glial Fibrillary Acidic Protein; Immunohistochemistry; Injections, Intraperitoneal; Male; Minocycline; Morphine; Naloxone; Opioid-Related Disorders; Oxycodone; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Weight Loss | 2009 |
Opioid tolerance development: a pharmacokinetic/pharmacodynamic perspective.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Humans; Kinetics; Models, Theoretical; Morphine; Oxycodone; Pain; Phosphorylation; Polymorphism, Genetic; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Time Factors | 2008 |
Is there a problem with oxycodone?
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Palliative Care; Prevalence; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Failure; Treatment Outcome; United Kingdom | 2008 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
Cost-effectiveness of strong opioids focussing on the long-term effects of opioid-related fractures: a model approach.
Topics: Accidental Falls; Aged; Analgesics, Opioid; Buprenorphine; Chronic Disease; Cost-Benefit Analysis; Fractures, Bone; Germany; Health Services; Humans; Markov Chains; Middle Aged; Models, Economic; Morphine; Oxycodone; Pain; Quality-Adjusted Life Years | 2009 |
FDA panel debates merits of next-generation opioid formulations.
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Approval; Humans; Morphine; Naltrexone; Oxycodone; United States; United States Food and Drug Administration | 2009 |
Prescription of opioids in Italy: everything, but the morphine.
Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Buprenorphine; Drug and Narcotic Control; Drug Prescriptions; Fentanyl; Guideline Adherence; Humans; Italy; Morphine; Neoplasms; Oxycodone; Pain; Practice Guidelines as Topic; Practice Patterns, Physicians'; Time Factors | 2009 |
mu-Opioid receptor-independent fashion of the suppression of sodium currents by mu-opioid analgesics in thalamic neurons.
Topics: Analgesics, Opioid; Animals; Cells, Cultured; Fentanyl; Membrane Potentials; Mice; Mice, Knockout; Morphine; Neurons; Opioid Peptides; Oxycodone; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sodium; Thalamus | 2009 |
Tracking the effects of policy changes in prescribing analgesics in one emergency department: a 10-year analysis.
Topics: Administration, Oral; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Emergencies; Emergency Medical Services; Emergency Service, Hospital; Guideline Adherence; Humans; Injections, Intravenous; Medical Audit; Meperidine; Morphine; Oxycodone; Pain; Pain Measurement | 2010 |
Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia.
Topics: Adolescent; Adult; Aged; Alleles; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Antiemetics; Consciousness; Cytochrome P-450 CYP2D6; Double-Blind Method; Female; Gene Frequency; Genotype; Humans; Injections, Intravenous; Intraoperative Care; Male; Middle Aged; Morphine; Neuromuscular Blocking Agents; Oxycodone; Oxymorphone; Pain Measurement; Pain, Postoperative; Polymorphism, Single Nucleotide; Young Adult | 2010 |
Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Fentanyl; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Morphine; Oxycodone; Pain; Pain Measurement | 2009 |
Prescription and administration of opioids to hospital in-patients, and barriers to effective use.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Australia; Cross-Sectional Studies; Drug Prescriptions; Drug Utilization; Ethnicity; Female; Health Knowledge, Attitudes, Practice; Humans; Inpatients; Male; Middle Aged; Morphine; Nurses; Oxycodone; Pain; Pain Measurement; Physicians; Tramadol; Young Adult | 2010 |
[Cost-effective analysis of rotation from sustained-release morphine tablet to transdermal fentanyl of matrix type or sustained-release oxycodone tablet].
Topics: Administration, Cutaneous; Analgesics, Opioid; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Delayed-Action Preparations; Fentanyl; Humans; Japan; Morphine; Oxycodone; Tablets | 2009 |
Tunable detection sensitivity of opiates in urine via a label-free porous silicon competitive inhibition immunosensor.
Topics: Antibodies; Binding, Competitive; Biosensing Techniques; Cocaine; Lab-On-A-Chip Devices; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Porosity; Silicon; Substance Abuse Detection | 2010 |
Quantitation of morphine, codeine, hydrocodone, hydromorphone, oxycodone, oxymorphone, and 6-monoacetylmorphine (6-MAM) in urine, blood, serum, or plasma using liquid chromatography with tandem mass spectrometry detection.
Topics: Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Reproducibility of Results; Tandem Mass Spectrometry | 2010 |
The dosing frequency of sustained-release opioids and the prevalence of end-of-dose failure in cancer pain control: a Korean multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Delayed-Action Preparations; Drug Administration Schedule; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Republic of Korea; Time Factors; Young Adult | 2010 |
Evaluation of the usefulness of an oxycodone immunoassay in combination with a traditional opiate immunoassay for the screening of opiates in urine.
Topics: Acetylation; Codeine; False Negative Reactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Hydrocodone; Hydromorphone; Immunoassay; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection | 2010 |
[Home hospice care for the lung cancer patients].
Topics: Analgesics, Opioid; Dyspnea; Fentanyl; Home Care Services; Hospice Care; Humans; Lung Neoplasms; Morphine; Oxycodone; Pain; Palliative Care | 2009 |
Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling.
Topics: Analgesics; Analgesics, Opioid; Animals; Cell Membrane; Enzyme Activation; Fentanyl; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Morphine; Oxycodone; Receptors, Opioid; Signal Transduction; Spinal Cord | 2010 |
Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Intraoperative Period; Ketorolac; Laparoscopy; Male; Middle Aged; Morphine; Oxycodone; Pain, Postoperative; Pregabalin; Premedication; Prostatectomy; Pyrazoles; Robotics; Sulfonamides | 2010 |
[Morphine or oxycodone tablets for pain?].
Topics: Acute Disease; Analgesics, Opioid; Animals; Chronic Disease; Delayed-Action Preparations; Drug Costs; Humans; Morphine; Oxycodone; Pain; Therapeutic Equivalency | 2010 |
The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestins; beta-Arrestins; Drug Tolerance; Fentanyl; Hot Temperature; Male; Methadone; Mice; Mice, Knockout; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Oxycodone; Pain; Pain Measurement; Pain Threshold; Receptors, Opioid, mu | 2011 |
A rapid recovery program: early home and pain free.
Topics: Amides; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Arthroplasty, Replacement, Knee; Bupivacaine; Case Management; Clinical Protocols; Early Ambulation; Epinephrine; Humans; Injections, Intra-Articular; Length of Stay; Morphine; Oxycodone; Pain, Postoperative; Patient Education as Topic; Patient Selection; Physical Therapy Modalities; Postoperative Care; Ropivacaine; Self-Help Devices; Vasoconstrictor Agents | 2010 |
Label-free porous silicon immunosensor for broad detection of opiates in a blind clinical study and results comparison to commercial analytical chemistry techniques.
Topics: Analgesics, Opioid; Biosensing Techniques; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Mass Spectrometry; Morphine; Oxycodone; Point-of-Care Systems; Porosity; Silicon | 2010 |
Determination of α(2)-adrenoceptor and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by agmatine and BMS182874.
Topics: Agmatine; Analgesics; Animals; Dansyl Compounds; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Oxycodone; Receptors, Adrenergic, alpha-2; Receptors, Endothelin; Yohimbine | 2011 |
Post-craniotomy pain in a paediatric population.
Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Craniotomy; Female; Humans; Ibuprofen; Infant; Male; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Pediatrics; Time Factors; Tramadol | 2011 |
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine | 2011 |
Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry.
Topics: Analgesics, Opioid; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection | 2011 |
Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Female; Fentanyl; Humans; Logistic Models; Male; Middle Aged; Morphine; Neoplasms; Odds Ratio; Oxycodone; Pain; Pain Management; Predictive Value of Tests; Retrospective Studies; Young Adult | 2011 |
Critical evaluation of the use of extinction paradigms for the assessment of opioid-induced conditioned place preference in rats.
Topics: Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Substance-Related Disorders | 2011 |
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Buprenorphine; Chromatography, Liquid; Cocaine; Codeine; Dronabinol; Ethylmorphine; Humans; Illicit Drugs; Methadone; Morphine; Oxycodone; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2011 |
Synergistic antihypersensitive effects of pregabalin and tapentadol in a rat model of neuropathic pain.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Disease Models, Animal; Drug Synergism; gamma-Aminobutyric Acid; Ligation; Locomotion; Male; Morphine; Neuralgia; Oxycodone; Pain Threshold; Phenols; Pregabalin; Rats; Rats, Sprague-Dawley; Spinal Nerves; Tapentadol | 2011 |
Drug overdose deaths--Florida, 2003-2009.
Topics: Alprazolam; Cause of Death; Cocaine; Drug Overdose; Florida; Humans; Illicit Drugs; Methadone; Morphine; Mortality; Oxycodone; Prescription Drugs | 2011 |
Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state.
Topics: Analgesics, Opioid; Animals; beta-Endorphin; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Hyperalgesia; Injections, Subcutaneous; Ligation; Male; Mice; Mice, Knockout; Morphine; Neuralgia; Oxycodone; Pain Measurement; Pain Threshold; Radioligand Assay; Receptors, Opioid, mu; Sciatic Nerve; Sodium Chloride; Spinal Cord | 2013 |
Safety and efficacy of immediate postoperative feeding and bowel stimulation to prevent ileus after major gynecologic surgical procedures.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Cathartics; Female; Gynecologic Surgical Procedures; Humans; Ileus; Incidence; Ketorolac Tromethamine; Length of Stay; Magnesium Hydroxide; Male; Middle Aged; Morphine; Oxycodone; Prospective Studies; Risk Factors; Time Factors; Treatment Outcome; Young Adult | 2011 |
Minimising the misuse of oxycodone and other pharmaceutical opioids in Australia.
Topics: Analgesics, Opioid; Drug and Narcotic Control; Female; Humans; Inappropriate Prescribing; Male; Morphine; Oxycodone; Pain; Prescription Drugs; Substance-Related Disorders | 2011 |
Prescription of opioid analgesics and related harms in Australia.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Australia; Cause of Death; Chronic Disease; Cross-Sectional Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug and Narcotic Control; Drug Overdose; Drug Utilization; Female; Guideline Adherence; Humans; Inappropriate Prescribing; Male; Morphine; Oxycodone; Pain; Prescription Drugs; Substance-Related Disorders; Suicide; Suicide Prevention; Young Adult | 2011 |
Inconsistencies in opioid equianalgesic ratios: clinical and research implications.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Dosage Calculations; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Randomized Controlled Trials as Topic | 2008 |
Narcotic-exposed neonates in a First Nations population in northwestern Ontario: incidence and implications.
Topics: Adolescent; Adult; Alcohol Drinking; Analgesics, Opioid; Female; Humans; Incidence; Indians, North American; Infant, Newborn; Length of Stay; Maternal-Fetal Exchange; Morphine; Neonatal Abstinence Syndrome; Ontario; Opioid-Related Disorders; Oxycodone; Pregnancy; Pregnancy Complications; Premature Birth; Retrospective Studies; Severity of Illness Index; Smoking; Young Adult | 2011 |
Clearing the smoke around medical marijuana.
Topics: Analgesics, Opioid; Chronic Pain; Dronabinol; Female; Humans; Male; Morphine; Oxycodone | 2011 |
Distinct relations among plasma concentrations required for different pharmacological effects in oxycodone, morphine, and fentanyl.
Topics: Analgesics; Analgesics, Opioid; Animals; Brain; Constipation; Dose-Response Relationship, Drug; Fentanyl; Male; Models, Animal; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley | 2011 |
Is maternal opioid use hazardous to breast-fed infants?
Topics: Age Factors; Analgesics, Opioid; Breast Feeding; Buprenorphine; Codeine; Female; Humans; Hydrocodone; Infant; Infant, Newborn; Meperidine; Methadone; Milk, Human; Morphine; Oxycodone | 2012 |
A multi-institutional study analyzing effect of prophylactic medication for prevention of opioid-induced gastrointestinal dysfunction.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Constipation; Female; Gastrointestinal Diseases; Humans; Japan; Laxatives; Magnesium Oxide; Male; Middle Aged; Morphine; Nausea; Neoplasms; Odds Ratio; Oxycodone; Pain; Vomiting | 2012 |
Stop and go strategy for opioid switching requires flexibility.
Topics: Analgesics, Opioid; Drug Substitution; Female; Humans; Male; Methadone; Morphine; Neoplasms; Oxycodone; Pain | 2012 |
Cost-effectiveness of tapentadol prolonged release compared with oxycodone controlled release in the UK in patients with severe non-malignant chronic pain who failed 1st line treatment with morphine.
Topics: Analgesics, Opioid; Chronic Pain; Cost-Benefit Analysis; Delayed-Action Preparations; Humans; Markov Chains; Morphine; Oxycodone; Phenols; Quality-Adjusted Life Years; Retrospective Studies; Severity of Illness Index; State Medicine; Surveys and Questionnaires; Tapentadol; United Kingdom | 2012 |
Dual-opioid therapy: changing the paradigm. Panel discussion.
Topics: Analgesics, Opioid; Animals; Clinical Trials as Topic; Drug Combinations; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Humans; Morphine; Oxycodone; Pain; Polypharmacy | 2012 |
The role of cannabinoids in chronic pain patients remains hazy.
Topics: Analgesics, Opioid; Chronic Pain; Dronabinol; Female; Humans; Male; Morphine; Oxycodone | 2012 |
Temperature-dependent enhancement of the antinociceptive effects of opioids in combination with gabapentin in mice.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Mice; Morphine; Oxycodone; Pain; Pain Measurement | 2012 |
Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats.
Topics: Animals; Antibodies; Antibody Specificity; Brain; Cross Reactions; Haptens; Heroin; Male; Mice; Mice, Inbred BALB C; Morphine; Morphine Derivatives; Oxycodone; Rats; Vaccines; Vaccines, Combined | 2012 |
Six-year follow-up of impact of co-proxamol withdrawal in England and Wales on prescribing and deaths: time-series study.
Topics: Accidents; Acetaminophen; Analgesics; Cause of Death; Dextropropoxyphene; Drug Combinations; Drug Overdose; England; Follow-Up Studies; Morphine; Oxycodone; Practice Patterns, Physicians'; Prescriptions; Suicide; Wales | 2012 |
Involvement of α₂-adrenoceptors, imidazoline, and endothelin-A receptors in the effect of agmatine on morphine and oxycodone-induced hypothermia in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Body Temperature Regulation; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Hypothermia; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Oxycodone; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
Use of reduced-dose periarticular injection for pain management in simultaneous bilateral total knee arthroplasty.
Topics: Aged; Amides; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bupivacaine; Case-Control Studies; Cefuroxime; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Epinephrine; Female; Fentanyl; Humans; Incidence; Injections, Intra-Articular; Ketoprofen; Male; Morphine; Oxycodone; Pain Management; Pain Measurement; Postoperative Complications; Prospective Studies; Pyrazoles; Ropivacaine; Statistics, Nonparametric; Sulfonamides; Treatment Outcome | 2012 |
Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Capsaicin; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Humans; Hyperalgesia; Lasers; Male; Middle Aged; Morphine; Oxycodone; Skin; Treatment Outcome; Ultraviolet Rays | 2012 |
General practitioners' and hospital physicians' preference for morphine or oxycodone as first-time choice for a strong opioid: a National Register-based study.
Topics: Ambulatory Care; Analgesics, Opioid; Attitude of Health Personnel; Denmark; General Practitioners; Humans; Morphine; Outpatients; Oxycodone; Physicians; Practice Patterns, Physicians'; Registries; Retrospective Studies | 2013 |
Development of a physiologically based pharmacokinetic model for the rat central nervous system and determination of an in vitro-in vivo scaling methodology for the blood-brain barrier permeability of two transporter substrates, morphine and oxycodone.
Topics: Animals; Blood-Brain Barrier; Caco-2 Cells; Central Nervous System; Humans; In Vitro Techniques; Morphine; Oxycodone; Permeability; Rats | 2012 |
Comparison of fatal poisonings by prescription opioids.
Topics: Accidents; Adolescent; Adult; Analgesics, Opioid; Buprenorphine; Central Nervous System Depressants; Codeine; Dextropropoxyphene; Drug Overdose; Ethanol; Fentanyl; Finland; Forensic Toxicology; Humans; Hypnotics and Sedatives; Methadone; Morphine; Opioid-Related Disorders; Oxycodone; Poisoning; Prescription Drug Misuse; Suicide; Tramadol; Young Adult | 2012 |
Differential activation of the μ-opioid receptor by oxycodone and morphine in pain-related brain regions in a bone cancer pain model.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Brain; Cell Line, Tumor; Disease Models, Animal; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred C3H; Morphine; Oxycodone; Pain; Receptors, Opioid, mu; Spinal Cord | 2013 |
Unpredictable absorption of oral opioid medications in a quadriplegic patient with chronic enterocutaneous fistulas.
Topics: Administration, Oral; Analgesics, Opioid; Benzodiazepines; Biological Availability; Chronic Disease; Chronic Pain; Humans; Intestinal Fistula; Male; Methadone; Morphine; Oxycodone; Quadriplegia; Young Adult | 2012 |
A simplified approach to direct SPE-MS.
Topics: Codeine; Female; Humans; Morphine; Oxycodone; Reference Values; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2012 |
The implications of tamper-resistant formulations for opioid rotation.
Topics: Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Drug Combinations; Drug Compounding; Drug Tolerance; Humans; Morphine; Naltrexone; Opioid-Related Disorders; Oxycodone; Oxymorphone; Patient Selection | 2012 |
[Prescription of high-potency opioids in 2011].
Topics: Administration, Cutaneous; Analgesics, Opioid; Drug Therapy, Combination; Drug Utilization; Fentanyl; Germany; Humans; Hydromorphone; Morphine; Oxycodone; Practice Patterns, Physicians' | 2012 |
False-positive buprenorphine EIA urine toxicology results due to high dose morphine: a case report.
Topics: Analgesics, Opioid; Buprenorphine; Chronic Disease; Enzyme Assays; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Low Back Pain; Male; Middle Aged; Morphine; Oxycodone; Reagent Kits, Diagnostic | 2012 |
Correlation between the administration of morphine or oxycodone and the development of infections in patients with cancer pain.
Topics: Analgesics, Opioid; Humans; Morphine; Neoplasms; Oxycodone; Pain; Retrospective Studies | 2013 |
Quantitative study of controlled substance bedside wasting, disposal and evaluation of potential ecologic effects.
Topics: Acetaminophen; Codeine; Controlled Substances; Drug Combinations; Ecotoxicology; Fentanyl; Hospitals; Hydrocodone; Ketamine; Medical Waste Disposal; Midazolam; Morphine; New York; Oxycodone; Wastewater | 2013 |
Oxycodone + naloxone: choose morphine and optimal laxative therapy instead.
Topics: Analgesics, Opioid; Constipation; Drug Combinations; Humans; Laxatives; Morphine; Naloxone; Oxycodone | 2013 |
Multimodal analgesia therapy reduces length of hospitalization in patients undergoing fusions of the ankle and hindfoot.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Spinal; Ankle Joint; Anti-Inflammatory Agents; Arthrodesis; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hydromorphone; Length of Stay; Male; Middle Aged; Morphine; Oxycodone; Pain Management; Pain, Postoperative; Postoperative Care; Prednisone; Pregabalin; Preoperative Care; Pyrazoles; Retrospective Studies; Subtalar Joint; Sulfonamides | 2013 |
G protein-gated inwardly rectifying potassium (KIR3) channels play a primary role in the antinociceptive effect of oxycodone, but not morphine, at supraspinal sites.
Topics: Animals; Brain; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Morphine; Narcotics; Neuralgia; Nociception; Oxycodone; Pain Measurement; Potassium Channel Blockers; RNA Interference; RNA, Small Interfering; Xenopus laevis | 2014 |
Only modest long-term opioid dose escalation occurs over time in chronic nonmalignant pain management.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Pain; Cohort Studies; Databases, Factual; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Tolerance; Female; Fentanyl; Humans; Longitudinal Studies; Male; Middle Aged; Morphine; Oxycodone; Retrospective Studies; Time Factors; Transdermal Patch; United Kingdom; Young Adult | 2013 |
Consumption of three strong opioids (morphine, oxycodone and fentanyl) in seven European countries during seven years (2003-2009).
Topics: Analgesics, Opioid; Drug Utilization; Europe; Fentanyl; Humans; Morphine; Oxycodone; Slovakia; Time Factors | 2013 |
Opioids in the treatment of postoperative pain: old drugs with new options?
Topics: Acetaminophen; Analgesics, Opioid; Drug Combinations; Drug Therapy, Combination; Fentanyl; Humans; Morphine; Oxycodone; Pain, Postoperative; Phenols; Sufentanil; Tapentadol | 2014 |
Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Behavior, Animal; Disease Models, Animal; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Male; Morphine; Neuralgia; Oxycodone; Protein Transport; Receptors, GABA-B; Spinal Cord | 2014 |
Rising opioid prescribing in adult U.S. emergency department visits: 2001-2010.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Emergency Service, Hospital; Female; Health Care Surveys; Humans; Hydrocodone; Hydromorphone; Male; Middle Aged; Morphine; Oxycodone; Pain; Pain Measurement; Patient Discharge; Practice Patterns, Physicians'; United States | 2014 |
In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Buprenorphine; Castor Oil; Constipation; Diarrhea; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Hot Temperature; Male; Morphine; Morphine Derivatives; Oxycodone; Pain; Pyrrolidines; Rats, Sprague-Dawley; Respiratory Insufficiency | 2015 |
A preliminary evaluation of the effects of opioids on innate and adaptive human in vitro immune function.
Topics: Adaptive Immunity; Adult; Analgesics, Opioid; Buprenorphine; Codeine; Fentanyl; Humans; Immunity, Innate; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Methadone; Monocytes; Morphine; Neutrophils; Oxycodone; Phagocytosis; Respiratory Burst; Tramadol | 2014 |
Changes in trends and pattern of strong opioid prescribing in primary care.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Cross-Sectional Studies; Drug Prescriptions; Drug Utilization; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; Primary Health Care; United Kingdom; Young Adult | 2014 |
Outpatient analgesia via paravertebral peripheral nerve block catheter and On-Q pump--a case series.
Topics: Acetaminophen; Adolescent; Amides; Analgesia; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bone Transplantation; Catheters; Child; Female; Fentanyl; Humans; Ilium; Infusion Pumps; Lumbar Vertebrae; Male; Morphine; Nerve Block; Outpatients; Oxycodone; Pain, Postoperative; Patient Satisfaction; Peripheral Nerves; Ropivacaine; Thoracic Vertebrae | 2014 |
A morphine-oxycodone combo pill: toward the "holy grail" for opioids or a justifiably rejected drug?
Topics: Drug Approval; Drug Combinations; Humans; Morphine; Oxycodone | 2014 |
Effect of the norepinephrine transporter (NET) inhibition on μ-opioid receptor (MOR)-induced anti-nociception in a bone cancer pain model.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C3H; Morphine; Neoplasm Transplantation; Norepinephrine Plasma Membrane Transport Proteins; Oxycodone; Pain; Phenols; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Tapentadol; Tramadol; Tumor Cells, Cultured | 2014 |
African Americans with cancer pain are more likely to receive an analgesic with toxic metabolite despite clinical risks: a mediation analysis study.
Topics: Analgesics; Black or African American; Female; Healthcare Disparities; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Renal Insufficiency, Chronic; Risk Factors | 2014 |
Morphine and oxycodone, but not fentanyl, exhibit antinociceptive effects mediated by G-protein inwardly rectifying potassium (GIRK) channels in an oxaliplatin-induced neuropathy rat model.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Fentanyl; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Male; Morphine; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Oxycodone; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2014 |
Establishment of opioid-induced rewarding effects under oxaliplatin- and Paclitaxel-induced neuropathy in rats.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Fentanyl; Male; Morphine; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Oxycodone; Paclitaxel; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance-Related Disorders | 2014 |
A microbial biomanufacturing platform for natural and semisynthetic opioids.
Topics: Bacterial Proteins; Codeine; Gene Dosage; Gene Expression; Hydrocodone; Hydromorphone; Metabolic Engineering; Metabolic Networks and Pathways; Morphine; Oxycodone; Papaver; Plant Proteins; Pseudomonas putida; Saccharomyces cerevisiae; Thebaine | 2014 |
Increasing use of opioids for pain.
Topics: Analgesics, Opioid; Buprenorphine; Drug Prescriptions; Female; Fentanyl; Humans; Male; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; Primary Health Care | 2014 |
Rapid dopamine transmission within the nucleus accumbens: dramatic difference between morphine and oxycodone delivery.
Topics: Animals; Dopamine; Electrochemistry; Infusions, Intravenous; Male; Microdialysis; Morphine; Nucleus Accumbens; Oxycodone; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2014 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Opioid Concentrations in Oral Fluid and Plasma in Cancer Patients With Pain.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Analgesics, Opioid; Blood Chemical Analysis; Delayed-Action Preparations; Drug Monitoring; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Mouth; Neoplasms; Oxycodone; Pain | 2015 |
Pick your poison: not all opioids are created equal in the eyes of dopamine (commentary on Vander Weele et al.).
Topics: Animals; Dopamine; Male; Morphine; Nucleus Accumbens; Oxycodone; Synaptic Transmission | 2014 |
Injection of crushed tablets--a prospective observational study.
Topics: Adolescent; Adult; Azabicyclo Compounds; Benzodiazepines; Buprenorphine; C-Reactive Protein; Female; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Male; Methylphenidate; Morphine; Oxycodone; Piperazines; Poison Control Centers; Pregabalin; Prospective Studies; Substance-Related Disorders; Sweden; Tablets; Young Adult | 2014 |
The contribution of Gi/o protein to opioid antinociception in an oxaliplatin-induced neuropathy rat model.
Topics: Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fentanyl; GTP-Binding Protein alpha Subunits, Gi-Go; Hyperalgesia; Male; Mediodorsal Thalamic Nucleus; Morphine; Nociception; Organoplatinum Compounds; Oxaliplatin; Oxycodone; Peripheral Nervous System Diseases; Pertussis Toxin; Rats, Sprague-Dawley; Receptors, Opioid, mu; Signal Transduction; Time Factors | 2014 |
Pharmacoeconomics evaluation of morphine, MS contin and oxycodone in the treatment of cancer pain.
Topics: Adult; Aged; Analgesics, Opioid; Economics, Pharmaceutical; Female; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Measurement; Prognosis | 2014 |
Enhanced GABAergic synaptic transmission at VLPAG neurons and potent modulation by oxycodone in a bone cancer pain model.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cell Line, Tumor; G Protein-Coupled Inwardly-Rectifying Potassium Channels; gamma-Aminobutyric Acid; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Mice, Inbred C3H; Morphine; Neurons; Oxycodone; Pain; Periaqueductal Gray; Synaptic Transmission | 2015 |
Comparing treatment-seeking codeine users and strong opioid users: Findings from a novel case series.
Topics: Adult; Codeine; Female; Humans; Male; Methadone; Middle Aged; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Oxycodone; Patient Acceptance of Health Care; Retrospective Studies | 2015 |
Influence of serum albumin levels during opioid rotation from morphine or oxycodone to fentanyl for cancer pain.
Topics: Analgesics, Opioid; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain; Serum Albumin | 2014 |
Differential effects of oxycodone, hydrocodone, and morphine on the responses of D2/D3 dopamine receptors.
Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Animals; Dopamine Agonists; Hot Temperature; Hydrocodone; Male; Mice, Inbred C57BL; Morphine; Oxycodone; Pain; Pain Measurement; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2015 |
Does therapeutic use of tapentadol cause false-positive urine screens for methadone or opiates?
Topics: Adult; Aged, 80 and over; Analgesics, Opioid; Chromatography, Gas; Chromatography, Liquid; False Positive Reactions; Female; Humans; Hydrocodone; Immunoenzyme Techniques; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Phenols; Predictive Value of Tests; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Tapentadol; Urinalysis | 2015 |
Pregabalin enhances the antinociceptive effect of oxycodone and morphine in thermal models of nociception in the rat without any pharmacokinetic interactions.
Topics: Analgesics, Opioid; Animals; Drug Interactions; Drug Therapy, Combination; Hot Temperature; Male; Morphine; Nociception; Oxycodone; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley | 2016 |
Opioid Overdose Deaths in the City and County of San Francisco: Prevalence, Distribution, and Disparities.
Topics: Adolescent; Adult; Aged; Black or African American; Cocaine; Drug Overdose; Female; Health Status Disparities; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Poverty Areas; Prevalence; San Francisco; Socioeconomic Factors; Young Adult | 2015 |
Technology: Barriers to misuse.
Topics: Analgesics, Opioid; Chemistry, Pharmaceutical; Drug Combinations; Drug Overdose; Drug Users; Humans; Morphine; Naltrexone; Opioid-Related Disorders; Oxycodone; Prodrugs | 2015 |
Discriminative stimulus effects of morphine and oxycodone in the absence and presence of acetic acid in male and female C57Bl/6 mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Operant; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Morphine; Oxycodone; Pain Measurement; Sex Characteristics | 2015 |
Accuracy of using Diagnosis Procedure Combination administrative claims data for estimating the amount of opioid consumption among cancer patients in Japan.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Codeine; Drug Prescriptions; Female; Fentanyl; Humans; Insurance Claim Review; Japan; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Tramadol | 2015 |
Opioid Analgesics and the Risk of Serious Infections Among Patients With Rheumatoid Arthritis: A Self-Controlled Case Series Study.
Topics: Adult; Age Factors; Analgesics, Opioid; Antirheumatic Agents; Arthritis, Rheumatoid; Codeine; Cohort Studies; Delayed-Action Preparations; Dextropropoxyphene; Hospitalization; Humans; Hydrocodone; Immunosuppressive Agents; Incidence; Infections; Medicaid; Middle Aged; Morphine; Oxycodone; Retrospective Studies; Risk Factors; Tennessee; United States | 2016 |
Comparative effects of Mitragyna speciosa extract, mitragynine, and opioid agonists on thermal nociception in rats.
Topics: Analgesics, Opioid; Animals; Male; Mitragyna; Morphine; Nociception; Oxycodone; Plant Extracts; Rats; Rats, Sprague-Dawley; Secologanin Tryptamine Alkaloids | 2016 |
[Sustained-release Opioids: Morphine, Oxycodone and Tapentadol].
Topics: Analgesics, Opioid; Delayed-Action Preparations; Drug Delivery Systems; Humans; Japan; Morphine; Oxycodone; Pain; Phenols; Tapentadol | 2015 |
Effect of estrogen on morphine- and oxycodone-induced antinociception in a female femur bone cancer pain model.
Topics: Analgesics; Animals; Bone Neoplasms; Cell Line, Tumor; Dynorphins; Estrogens; Estrous Cycle; Female; Femur; Gene Expression Regulation; Male; Mice; Morphine; Ovariectomy; Oxycodone; Pain | 2016 |
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli.
Topics: Acetyltransferases; Analgesics, Opioid; Benzylisoquinolines; Codeine; Coptis; Escherichia coli; Fermentation; Glycerol; Hydrocodone; Methyltransferases; Morphine; Organisms, Genetically Modified; Oxidoreductases; Oxycodone; Papaver; Thebaine | 2016 |
Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach.
Topics: Analgesics, Opioid; Animals; Cell Line; Cell Survival; Drug Therapy, Combination; Flow Cytometry; Humans; Mice; Morphine; Motor Neurons; Neuroblastoma; Neurotoxicity Syndromes; Oxycodone | 2016 |
Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels.
Topics: Analgesics, Opioid; Cholesterol; Female; Fentanyl; Humans; Lung Neoplasms; Male; Morphine; Oxycodone; Pain Management | 2016 |
Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Delirium; Drug-Related Side Effects and Adverse Reactions; Female; Fentanyl; Humans; Incidence; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Palliative Care | 2017 |
LC-MS-MS Method for Analysis of Opiates in Wastewater During Football Games II.
Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Football; Humans; Hydrocodone; Hydromorphone; Morphine; Opiate Alkaloids; Oxycodone; Oxymorphone; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2016 |
Combined Effect of Opioids and Corticosteroids for Alleviating Dyspnea in Terminal Cancer Patients: A Retrospective Review.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyspnea; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Quality of Life; Retrospective Studies; Terminal Care; Treatment Outcome | 2016 |
A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain.
Topics: Analgesics, Opioid; Humans; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative | 2016 |
Author's Reply to Parsons: "Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach".
Topics: Analgesics, Opioid; Animals; Humans; Mice; Morphine; Neuroblastoma; Oxycodone; Pain; Pain Measurement | 2016 |
Comment on: "Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach".
Topics: Analgesics, Opioid; Animals; Humans; Mice; Morphine; Neuroblastoma; Oxycodone; Pain; Pain Measurement | 2016 |
Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain.
Topics: Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cardiovascular Diseases; Cause of Death; Chronic Pain; Drug Overdose; Drug Prescriptions; Female; Fentanyl; Humans; Male; Methadone; Middle Aged; Morphine; Oxycodone; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk | 2016 |
Do Diuretics have Antinociceptive Actions: Studies of Spironolactone, Eplerenone, Furosemide and Chlorothiazide, Individually and with Oxycodone and Morphine.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Brain; Chlorothiazide; Disease Models, Animal; Diuretics; Drug Interactions; Drug Therapy, Combination; Eplerenone; Furosemide; Male; Morphine; Neurons; Oxycodone; Pain; Rats, Sprague-Dawley; Spironolactone; Tissue Distribution | 2017 |
Long-Acting Opioid Use Independently Predicts Perioperative Complication in Total Joint Arthroplasty.
Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Female; Humans; Length of Stay; Male; Middle Aged; Morphine; Oxycodone; Patient Discharge; Postoperative Complications; Postoperative Period; Preoperative Period; Retrospective Studies; Risk Factors | 2016 |
New Initiation of Long-Acting Opioids in Long-Stay Nursing Home Residents.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Buprenorphine; Chronic Pain; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Utilization; Female; Fentanyl; Homes for the Aged; Humans; Long-Term Care; Male; Morphine; Nursing Homes; Oxycodone; Oxymorphone; Practice Patterns, Physicians'; Rhode Island; Tramadol | 2016 |
Contribution of Opiate Analgesics to the Development of Infections in Advanced Cancer Patients.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; Follow-Up Studies; Humans; Infections; Logistic Models; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain Management; Palliative Care; Retrospective Studies; Risk Factors | 2017 |
Prescription opioid dispensing and prescription opioid poisoning: Population data from Victoria, Australia 2006 to 2013.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Australia; Cause of Death; Child; Child, Preschool; Drug Overdose; Drug Prescriptions; Female; Hospitalization; Humans; Inappropriate Prescribing; Infant; Infant, Newborn; Male; Middle Aged; Morphine; Oxycodone; Population Surveillance; Prescription Drugs; Young Adult | 2017 |
Long-lasting effects of adolescent oxycodone exposure on reward-related behavior and gene expression in mice.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Morphine; Narcotics; Nucleus Accumbens; Oxycodone; Receptors, Dopamine; Reward; Ventral Tegmental Area | 2016 |
Dose and Duration of Opioid Use in Patients with Cancer and Noncancer Pain at an Outpatient Hospital Setting in Malaysia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fentanyl; Humans; Malaysia; Male; Middle Aged; Morphine; Neoplasms; Outpatient Clinics, Hospital; Oxycodone; Pain; Retrospective Studies; Young Adult | 2017 |
Degradation of Opioids and Opiates During Acid Hydrolysis Leads to Reduced Recovery Compared to Enzymatic Hydrolysis.
Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Cytochrome P-450 CYP2D6; Glucuronidase; Humans; Hydrocodone; Hydrolysis; Hydromorphone; Morphine; Morphine Derivatives; Opiate Alkaloids; Oxycodone; Oxymorphone; Specimen Handling; Tandem Mass Spectrometry | 2016 |
[From ketobemidone to morphine or oxycodone].
Topics: Administration, Intravenous; Analgesics, Opioid; Drug Substitution; Humans; Meperidine; Morphine; Norway; Oxycodone; Practice Guidelines as Topic | 2016 |
Reply to: Agonism at delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice.
Topics: Analgesics, Opioid; Animals; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Oxycodone; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 2016 |
Micronized Organic Magnesium Salts Enhance Opioid Analgesia in Rats.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Drug Synergism; Magnesium Compounds; Male; Morphine; Oxycodone; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Tramadol | 2016 |
Chronic Use of Opioids Before and After Total Knee Arthroplasty: A Retrospective Cohort Study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthralgia; Arthroplasty, Replacement, Knee; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Morphine; Osteoarthritis, Knee; Oxycodone; Pain, Postoperative; Postoperative Period; Retrospective Studies; Risk Factors | 2017 |
High-Dose Opioid Prescribing and Opioid-Related Hospitalization: A Population-Based Study.
Topics: Adolescent; Adult; Analgesics, Opioid; Canada; Drug Administration Schedule; Female; Fentanyl; Hospitalization; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Young Adult | 2016 |
Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer.
Topics: Analgesics; Animals; Butadienes; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Mice; Morphine; Nitriles; Oxycodone; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Reward; Up-Regulation; Ventral Tegmental Area | 2017 |
Burn injury decreases the antinociceptive effects of opioids.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Burns; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrocodone; Male; Mice; Mice, Inbred C57BL; Morphine; Oxycodone; Pain; Pain Threshold; Time Factors | 2017 |
Evaluation of 6 remote First Nations community-based buprenorphine programs in northwestern Ontario: Retrospective study.
Topics: Adult; Benzodiazepines; Buprenorphine; Cocaine; Community Health Services; Counseling; Drug Therapy, Combination; Female; Humans; Indians, North American; Male; Medication Adherence; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Ontario; Opiate Substitution Treatment; Opioid-Related Disorders; Oxycodone; Program Evaluation; Retrospective Studies; Rural Health Services; Substance Abuse Detection; Suicide; Young Adult | 2017 |
Hydrocodone is More Effective than Morphine or Oxycodone in Suppressing the Development of Burn-Induced Mechanical Allodynia.
Topics: Analgesics, Opioid; Animals; Burns; Dose-Response Relationship, Drug; Hydrocodone; Hyperalgesia; Male; Mice, Inbred C57BL; Morphine; Oxycodone; Pain; Pain Measurement; Pain Threshold | 2017 |
Patients at Risk: Large Opioid Prescriptions After Total Knee Arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Drug Combinations; Drug Prescriptions; Female; Follow-Up Studies; Humans; Hydrocodone; Hydromorphone; Knee Joint; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Patient Discharge; Reoperation; Retrospective Studies | 2017 |
[Opioid prescription changes in Sweden 2000–2015].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Dextropropoxyphene; Drug Prescriptions; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; Sweden; Tramadol; Young Adult | 2017 |
Intrathecal Morphine and Oral Analgesics Provide Safe and Effective Pain Control After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis.
Topics: Adolescent; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Female; Fentanyl; Humans; Male; Morphine; Oxycodone; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Period; Retrospective Studies; Scoliosis; Spinal Fusion; Treatment Outcome | 2018 |
Effects of ibudilast on oxycodone-induced analgesia and subjective effects in opioid-dependent volunteers.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Double-Blind Method; Humans; Morphine; Oxycodone; Pain Measurement; Pain Threshold; Pilot Projects; Pyridines; Volunteers | 2017 |
The Conversion Ratio From Intravenous Hydromorphone to Oral Opioids in Cancer Patients.
Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Drug Dosage Calculations; Female; Humans; Hydromorphone; Linear Models; Male; Middle Aged; Morphine; Oxycodone; Palliative Care; Patient Discharge; Retrospective Studies; Treatment Outcome; Young Adult | 2017 |
Supramolecular Sensors for Opiates and Their Metabolites.
Topics: Calibration; Chemistry Techniques, Analytical; Fluorescence; Heroin; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Morphine; Opiate Alkaloids; Oxycodone | 2017 |
Trends in heroin and pharmaceutical opioid overdose deaths in Australia.
Topics: Analgesics, Opioid; Australia; Drug Overdose; Fentanyl; Heroin; Humans; Morphine; Opioid-Related Disorders; Oxycodone; Pharmaceutical Preparations; Tramadol | 2017 |
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach.
Topics: Acetaminophen; Animals; Biological Transport; Brain; Brain Injuries, Traumatic; Central Nervous System Agents; Epilepsy; Humans; Models, Biological; Morphine; Oxycodone; Phenytoin; Rats | 2018 |
In contrast to morphine, buprenorphine enhances macrophage-induced humoral immunity and, as oxycodone, slightly suppresses the effector phase of cell-mediated immune response in mice.
Topics: Animals; Buprenorphine; Cells, Cultured; Cytokines; Dermatitis, Contact; Homeostasis; Humans; Immunity, Cellular; Immunity, Humoral; Immunomodulation; Macrophages; Male; Mice; Mice, Inbred CBA; Morphine; Nitric Oxide; Oxycodone; Reactive Oxygen Species | 2018 |
Relationship between receptor occupancy and the antinociceptive effect of mu opioid receptor agonists in male rats.
Topics: Analgesics, Opioid; Animals; Autoradiography; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Morphine; Nociception; Oxycodone; Pain Measurement; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Thalamus; Time Factors; Tritium | 2018 |
Postoperative analgesia choices in total knee replacement.
Topics: Analgesia, Patient-Controlled; Arthroplasty, Replacement, Knee; Humans; Morphine; Naloxone; Oxycodone | 2018 |
Patterns of regional variation of opioid prescribing in primary care in England: a retrospective observational study.
Topics: Analgesics, Opioid; Buprenorphine; Chronic Pain; Crime; Databases, Factual; Education; Employment; England; Health Status; Housing; Humans; Income; Methadone; Morphine; Oxycodone; Practice Patterns, Physicians'; Primary Health Care; Residence Characteristics; Retrospective Studies; Socioeconomic Factors; Tramadol | 2018 |
Development of a Quantitative LC-MS-MS Assay for Codeine, Morphine, 6-Acetylmorphine, Hydrocodone, Hydromorphone, Oxycodone and Oxymorphone in Neat Oral Fluid.
Topics: Analgesics, Opioid; Calibration; Chromatography, Liquid; Codeine; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Opioid-Related Disorders; Oxycodone; Oxymorphone; Predictive Value of Tests; Reference Standards; Reproducibility of Results; Saliva; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2018 |
The James A. Rand Young Investigator's Award: Battling the Opioid Epidemic with Prospective Pain Threshold Measurement.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Awards and Prizes; Drug Utilization; Female; History, 21st Century; Humans; Knee Joint; Male; Middle Aged; Morphine; Orthopedics; Oxycodone; Pain Management; Pain Measurement; Pain Threshold; Pain, Postoperative; Postoperative Period; Prospective Studies | 2018 |
Chronic oxycodone induces axonal degeneration in rat brain.
Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Female; Morphine; Oxycodone; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2018 |
Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.
Topics: Analgesics, Opioid; Animals; Ethanol; Male; Mice; Morphine; Oxycodone; Pregabalin; Protein Kinase C; Protein Kinase Inhibitors; Respiratory Insufficiency | 2018 |
Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine: from behaviour to drug availability.
Topics: Analgesics; Analgesics, Opioid; Animals; Drug Interactions; Drug Tolerance; Ketamine; Male; Models, Animal; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley | 2018 |
Opioid Sparing in Cleft Palate Surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cleft Palate; Female; Humans; Infant; Length of Stay; Male; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Retrospective Studies; Treatment Outcome | 2018 |
Doctor shopping of opioid analgesics relative to benzodiazepines: A pharmacoepidemiological study among 11.7 million inhabitants in the French countries.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Databases, Factual; Drug Prescriptions; Fentanyl; Humans; Male; Morphine; Opioid-Related Disorders; Oxycodone; Pain; Pharmacoepidemiology; Practice Patterns, Physicians'; Prescription Drug Misuse | 2018 |
Nociceptin/orphanin FQ receptors modulate the discriminative stimulus effects of oxycodone in C57BL/6 mice.
Topics: Analgesics, Opioid; Animals; Benzimidazoles; Imidazoles; Ligands; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Nociceptin Receptor; Opioid-Related Disorders; Oxycodone; Piperidines; Receptors, Opioid; Spiro Compounds | 2018 |
Storing and Disposing of Opioid Analgesics: What Does Our Medicine Tell Us?
Topics: Analgesics, Opioid; Drug Labeling; Drug Storage; Fentanyl; Humans; Hydrocodone; Hydromorphone; Medical Waste Disposal; Morphine; Oxycodone; Prescription Drug Diversion; Safety; Tramadol | 2018 |
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Ibuprofen; Morphine; Opioid-Related Disorders; Oxycodone; Pain Management; Pain, Postoperative; Pregnancy; Retrospective Studies; Surgical Wound; Young Adult | 2019 |
Comparative out-of-hospital mortality of long-acting opioids prescribed for non-cancer pain: A retrospective cohort study.
Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Drug Overdose; Female; Fentanyl; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Oxycodone; Retrospective Studies; Transdermal Patch | 2019 |
A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.
Topics: Analgesics, Opioid; Animals; Drug Design; Hyperalgesia; Ligands; Morphine; Nociceptin; Nociception; Opioid Peptides; Oxycodone; Primates; Receptors, Opioid, mu; Structure-Activity Relationship | 2018 |
Opioid Prescribing Behavior in Long-Term Geriatric Care in the Netherlands.
Topics: Adult; Aged; Analgesics, Opioid; Cross-Sectional Studies; Drug Prescriptions; Female; Fentanyl; Geriatrics; Guideline Adherence; Humans; Long-Term Care; Male; Middle Aged; Morphine; Netherlands; Oxycodone; Pain; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires; Young Adult | 2018 |
At-a-glance - The role of opioid toxicity in suicide deaths in Alberta, 2000 to 2016.
Topics: Adult; Age Factors; Alberta; Analgesics, Opioid; Codeine; Female; Humans; Hydromorphone; International Classification of Diseases; Male; Middle Aged; Morphine; Oxycodone; Sex Factors; Suicide; Vital Statistics | 2018 |
The G-protein biased mu-opioid agonist, TRV130, produces reinforcing and antinociceptive effects that are comparable to oxycodone in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; GTP-Binding Proteins; Male; Morphine; Oxycodone; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement, Psychology; Spiro Compounds; Thiophenes; Treatment Outcome | 2018 |
Short term exposure to oxycodone alters the survival, proliferation and differentiation of rat embryonic neural stem cell in vitro.
Topics: Analgesics, Opioid; Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Cell Survival; Embryonic Stem Cells; Female; Morphine; Naltrexone; Neural Stem Cells; Oxycodone; Pregnancy; Rats; Rats, Sprague-Dawley | 2018 |
Trends in the consumption of opioids for the treatment of severe pain in Europe, 1990-2016.
Topics: Analgesics, Opioid; Europe; European Union; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; Oxycodone; Pain; Practice Patterns, Physicians'; Regression Analysis; United States | 2019 |
Opioid responsiveness of nociceptive versus mixed pain in clinical cancer patients.
Topics: Aged; Analgesics; Analgesics, Opioid; Cancer Pain; Drug Therapy, Combination; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Neuralgia; Nociceptive Pain; Oxycodone; Pain Measurement; Prospective Studies | 2018 |
Comparison of the use of different analgesics in the course of anesthesia care based on pharmacoeconomics.
Topics: Analgesics; Anesthesia; Delayed-Action Preparations; Economics, Pharmaceutical; Fentanyl; Humans; Morphine; Oxycodone; Pain; Pain Measurement; Piperazines; Tablets | 2018 |
Pharmaceutical payments to physicians may increase prescribing for opioids.
Topics: Analgesics, Opioid; Disclosure; Drug Industry; Fentanyl; Humans; Hydrocodone; Marketing; Medicare Part D; Morphine; Multivariate Analysis; Oxycodone; Physicians; Practice Patterns, Physicians'; Tapentadol; United States | 2019 |
Identification of opioids in surface and wastewaters by LC/QTOF-MS using retrospective data analysis.
Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Data Analysis; Environmental Monitoring; Fentanyl; Heroin; Hydrocodone; Hydromorphone; Minnesota; Morphine; Morphine Derivatives; Oxycodone; Retrospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Tramadol; Wastewater; Water Pollutants, Chemical | 2019 |
Outcomes Associated with Treatment of Chronic Pain with Tapentadol Compared with Morphine and Oxycodone: A UK Primary Care Observational Study.
Topics: Adult; Aged; Analgesics, Opioid; Chronic Pain; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Management; Tapentadol; United Kingdom | 2019 |
Comparison of the antinociceptive profiles of morphine and oxycodone in two models of inflammatory and osteoarthritic pain in rat.
Topics: Analgesics; Animals; Disease Models, Animal; Hyperalgesia; Inflammation; Locomotion; Male; Morphine; Osteoarthritis, Knee; Oxycodone; Pain; Rats; Rats, Wistar; Receptors, Opioid | 2019 |
Expert consensus on the management of breakthrough cancer pain in older patients. A Delphi study.
Topics: Administration, Mucosal; Aged; Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Central Nervous System Depressants; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Decision Making, Shared; Delphi Technique; Drug Interactions; Fentanyl; Frailty; Geriatric Assessment; Geriatrics; Humans; Medical Oncology; Morphine; Oxycodone; Pain Management; Pain Measurement; Palliative Medicine; Patient Care Team; Practice Guidelines as Topic | 2019 |
Current Status of Adverse Events Related with Opioid Analgesics in Japan: Assessment Based on Japanese Adverse Drug Event Report Database.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Databases, Factual; Fentanyl; Humans; Japan; Methadone; Morphine; Oxycodone; Tapentadol | 2019 |
Placental trophoblast transfer of opioids following exposures to individual or mixtures of opioids
Topics: Analgesics, Opioid; Female; Fentanyl; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Maternal-Fetal Exchange; Methadone; Morphine; Naloxone; Oxycodone; Placenta; Pregnancy; Trophoblasts | 2019 |
Side effects from opioids used for acute pain after emergency department discharge.
Topics: Adult; Aged; Analgesics, Opioid; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain; Pain Management; Pain Measurement; Patient Discharge; Prospective Studies | 2020 |
A preliminary study of the effect of naldemedine tosylate on opioid-induced nausea and vomiting.
Topics: Aged; Analgesics, Opioid; Antiemetics; Constipation; Female; Humans; Incidence; Male; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Nausea; Oxycodone; Receptors, Opioid; Retrospective Studies; Vomiting | 2020 |
The Current Practice of Opioid for Cancer Dyspnea: The Result From the Nationwide Survey of Japanese Palliative Care Physicians.
Topics: Analgesics, Opioid; Dyspnea; Fentanyl; Humans; Japan; Morphine; Neoplasms; Oxycodone; Palliative Care; Patient Selection; Practice Patterns, Physicians'; Surveys and Questionnaires | 2019 |
Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats.
Topics: Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Fentanyl; Male; Morphine; Neuralgia; Oxycodone; Pain Measurement; Rats, Sprague-Dawley | 2019 |
Medical Use of Long-term Extended-release Opioid Analgesics in Commercially Insured Adults in the United States.
Topics: Adult; Aged; Analgesics, Opioid; Arthritis; Back Pain; Cancer Pain; Chronic Pain; Delayed-Action Preparations; Duration of Therapy; Female; Fentanyl; Humans; Insurance, Health; Male; Middle Aged; Morphine; Oxycodone; Tramadol; United States | 2020 |
Behavioral Effects of Opioid Full and Partial Agonists During Chronic Buprenorphine Treatment.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Buprenorphine; Dose-Response Relationship, Drug; Drug Partial Agonism; Male; Morphine; Oxycodone; Pain Measurement; Receptors, Opioid, mu; Saimiri; Self Administration | 2019 |
Severe lumbar radiculopathy with epidural venous plexus engorgement in a morbidly obese pediatric patient: A case report.
Topics: Adolescent; Analgesics, Opioid; Anesthesia, Caudal; Humans; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Morphine; Obesity; Oxycodone; Pain Measurement; Pain, Intractable; Radiculopathy | 2019 |
A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guanosine 5'-O-(3-Thiotriphosphate); Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Oxycodone; Pain Measurement; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 2020 |
Both Race and Insurance Type Independently Predict the Selection of Oral Opioids Prescribed to Cancer Outpatients.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Cancer Pain; Female; Humans; Insurance Coverage; Logistic Models; Male; Middle Aged; Morphine; Neoplasms; Outpatients; Oxycodone; Racial Groups | 2020 |
Narcotic-Free Perioperative Total Knee Arthroplasty: Does the Periarticular Injection Medication Make a Difference?
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Drug Combinations; Drug Utilization; Epinephrine; Female; Humans; Injections, Intra-Articular; Ketorolac; Length of Stay; Male; Morphine; Oxycodone; Pain Management; Pain, Postoperative; Retrospective Studies; Tramadol | 2021 |
Effectiveness of rapid titration with intravenous administration of oxycodone injection in advanced cancer patients with severe pain.
Topics: Administration, Intravenous; Adult; Aged; Analgesics, Opioid; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Morphine; Neoplasms; Oxycodone; Pain; Pain Management; Pain Measurement; Retrospective Studies | 2019 |
Paternal morphine exposure induces bidirectional effects on cocaine versus opioid self-administration.
Topics: Acetylation; Analgesics, Opioid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Female; Histone Code; Male; Morphine; Motivation; Oxycodone; Paternal Exposure; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Self Administration; Seminiferous Tubules | 2020 |
Comparing rates and characteristics of ambulance attendances related to extramedical use of pharmaceutical opioids in Victoria, Australia from 2013 to 2018.
Topics: Adolescent; Adult; Aged; Ambulances; Analgesics, Opioid; Child; Codeine; Drug Overdose; Emergency Medical Services; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Naloxone; Oxycodone; Practice Patterns, Physicians'; Prescription Drug Misuse; Retrospective Studies; Victoria; Young Adult | 2020 |
The Pinderfields hospital pain management protocol for enzymatic debridement of burns wounds.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Body Surface Area; Bromelains; Burns; Codeine; Debridement; Gabapentin; Humans; Ibuprofen; Levobupivacaine; Morphine; Oxycodone; Pain Management; Pain Measurement; Pain, Procedural | 2020 |
Comparative Analysis of ELISA Immunoassay and LC-QTOF for Opiate Screening.
Topics: Analgesics, Opioid; Chromatography, Liquid; Codeine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocodone; Hydromorphone; Morphine; Morphine Derivatives; Oxycodone; Oxymorphone; Substance Abuse Detection | 2020 |
[Efficacy of Oxycodone Hydrochloride for Patient-controlled Intravenous Analgesia after General Surgery].
Topics: Analgesia, Patient-Controlled; Humans; Morphine; Oxycodone; Pain, Postoperative; Retrospective Studies; Sufentanil; Surgical Procedures, Operative | 2020 |
The impact of the prescription opioid epidemic on young children: Trends and mortality.
Topics: Analgesics, Opioid; Buprenorphine; Child, Preschool; Epidemics; Female; Fentanyl; Humans; Infant; Male; Methadone; Morphine; Opioid Epidemic; Oxycodone; Poison Control Centers; Prescription Drugs | 2020 |
Lipid microsphere bound oxycodone for pain management in patients receiving radiotherapy for head and neck cancer.
Topics: Analgesia; Analgesics, Opioid; Deglutition Disorders; Delayed-Action Preparations; Female; Gastrostomy; Head and Neck Neoplasms; Humans; Male; Microspheres; Middle Aged; Morphine; Mucositis; Opioid-Related Disorders; Oxycodone; Pain; Pain Management; Prospective Studies; Quality of Life | 2021 |
A Multimodal Protocol to Diminish Pain Following Common Orthopedic Sports Procedures: Can We Eliminate Postoperative Opioids?
Topics: Adolescent; Adult; Analgesia; Analgesics, Opioid; Anterior Cruciate Ligament; Anxiety; Arthroscopy; Athletic Injuries; Depression; Female; Humans; Male; Meniscectomy; Middle Aged; Morphine; Opioid-Related Disorders; Orthopedics; Oxycodone; Pain Management; Pain, Postoperative; Patient Satisfaction; Postoperative Period; Prospective Studies; Rotator Cuff; Shoulder Joint; Visual Analog Scale; Young Adult | 2020 |
[Analysis of Symptoms Relieved in Addition to Pain after Administration of Oxycodone or Morphine to Patients with Advanced Cancer Living at Home].
Topics: Administration, Cutaneous; Analgesics, Opioid; Cancer Pain; Fentanyl; Humans; Morphine; Neoplasms; Oxycodone; Pain | 2020 |
Reduction of Drug-Drug Interaction Risk; CDC Guidelines Influence on Opiate Benzodiazepine Prescribing.
Topics: Benzodiazepines; Centers for Disease Control and Prevention, U.S.; Drug Interactions; Drug Therapy, Combination; Guideline Adherence; Humans; Hydrocodone; Morphine; Opiate Alkaloids; Opioid-Related Disorders; Oxycodone; Pain; Pharmaceutical Preparations; United States | 2020 |
Development of Persistent Opioid Use After Cardiac Surgery.
Topics: Cardiac Surgical Procedures; Female; Humans; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Retrospective Studies; Risk Factors; Time Factors | 2020 |
Neurophysiological response properties of medullary pain-control neurons following chronic treatment with morphine or oxycodone: modulation by acute ketamine.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Excitatory Amino Acid Antagonists; Hyperalgesia; Ketamine; Male; Medulla Oblongata; Morphine; Nociception; Oxycodone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2020 |
Trends in hydrocodone combination product exposures reported to California Poison Control System (CPCS) following DEA rescheduling.
Topics: California; Codeine; Drug and Narcotic Control; Drug Overdose; Drug Prescriptions; Fentanyl; Heroin; Humans; Hydrocodone; Interrupted Time Series Analysis; Morphine; Oxycodone; Poison Control Centers; Tramadol | 2021 |
Opioid consumption in two surgical hospital wards.
Topics: Analgesics, Opioid; Hospitals; Humans; Morphine; Norway; Oxycodone | 2020 |
Chronic opioid exposure differentially modulates oxycodone self-administration in male and female rats.
Topics: Animals; Female; Male; Morphine; Narcotics; Opioid-Related Disorders; Oxycodone; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome | 2021 |
Tramadol non-medical use in Four European countries: A comparative analysis.
Topics: Adult; Analgesics, Opioid; Codeine; Cross-Sectional Studies; Europe; Female; Germany; Humans; Italy; Male; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Prescription Drug Misuse; Prescription Drugs; Spain; Tramadol; United Kingdom; Young Adult | 2020 |
Opioid Consumption After Knee Arthroscopy.
Topics: Adult; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Arthroscopy; Evidence-Based Medicine; Female; Humans; Knee Joint; Male; Meniscectomy; Middle Aged; Morphine; Oxycodone; Pain Measurement; Pain, Postoperative; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies | 2021 |
How Successful Is Parenteral Oxycodone for Relieving Terminal Cancer Dyspnea Compared With Morphine? A Multicenter Prospective Observational Study.
Topics: Aged; Analgesics, Opioid; Dyspnea; Humans; Lung Neoplasms; Morphine; Oxycodone | 2021 |
Methadone-mediated sensitization of glioblastoma cells is drug and cell line dependent.
Topics: Analgesics, Opioid; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Glioblastoma; Humans; Methadone; Morphine; Naloxone; Oxycodone; Receptors, Opioid, mu; Tumor Cells, Cultured | 2021 |
Methylnaltrexone crosses the blood-brain barrier and attenuates centrally-mediated behavioral effects of morphine and oxycodone in mice.
Topics: Analgesics, Opioid; Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Oxycodone; Pain Measurement; Quaternary Ammonium Compounds | 2021 |
Adolescent oxycodone exposure inhibits withdrawal-induced expression of genes associated with the dopamine transmission.
Topics: Analgesics, Opioid; Animals; Dopamine; Epigenesis, Genetic; Gene Expression; Male; Mice; Morphine; Opioid-Related Disorders; Oxycodone; Reward; Self Administration; Ventral Tegmental Area | 2021 |
Analgesic efficacy of morphine sulfate immediate release vs. oxycodone/acetaminophen for acute pain in the emergency department.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Morphine; Oxycodone; Pain Management | 2021 |
Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain.
Topics: Analgesics, Opioid; Animals; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Female; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Neuralgia; Oxycodone; Pain Measurement; Piperidines; Receptors, Opioid, mu; Treatment Outcome | 2021 |
Impact of a multimodal analgesic protocol modification on opioid consumption after cesarean delivery: a retrospective cohort study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ketorolac; Morphine; Oxycodone; Pain, Postoperative; Pregnancy; Retrospective Studies | 2022 |
Monitoring Equianalgesic Opioid Dosing.
Topics: Administration, Oral; Analgesics, Opioid; Dose-Response Relationship, Drug; Hospice and Palliative Care Nursing; Humans; Infusions, Parenteral; Morphine; Nurse's Role; Oxycodone; Pain Measurement; Palliative Care | 2021 |
Opioid use after cesarean: a cohort study comparing combined versus separate oxycodone and acetaminophen regimens.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Pain, Postoperative; Pregnancy; Retrospective Studies | 2022 |
Trends in Postpartum Opioid Prescribing: A Time Series Analysis.
Topics: Adult; Analgesics, Opioid; Breast Feeding; Codeine; Female; Humans; Hydromorphone; Infant, Newborn; Interrupted Time Series Analysis; Lactation; Morphine; Ontario; Oxycodone; Postpartum Period; Practice Patterns, Physicians'; Pregnancy; Young Adult | 2021 |
Pharmaceutical opioid poisonings in Victoria, Australia: Rates and characteristics of a decade of emergency department presentations among nine pharmaceutical opioids.
Topics: Adolescent; Adult; Analgesics, Opioid; Child; Codeine; Drug Overdose; Emergency Service, Hospital; Female; Fentanyl; Humans; Morphine; Oxycodone; Pharmaceutical Preparations; Tramadol; Victoria; Young Adult | 2022 |
Comparative analysis of the effects of opioids in angiogenesis.
Topics: Analgesics, Opioid; Cell Proliferation; Cells, Cultured; Endothelial Cells; Fentanyl; Humans; Mitogen-Activated Protein Kinases; Morphine; Neovascularization, Physiologic; Oxycodone; Phosphorylation; Umbilical Veins | 2021 |
A 13-Year National Monitoring Study to Assess Narcotic Prescriptions and Indications (2007-2019).
Topics: Aged; Analgesics, Opioid; Cross-Sectional Studies; Drug Prescriptions; Female; Fentanyl; Humans; Male; Middle Aged; Morphine; Narcotics; Oxycodone; Practice Patterns, Physicians' | 2022 |
Analgesic Effects of Different
Topics: Analgesia; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Nalbuphine; Oxycodone; Pain Management; Pain Measurement; Pain, Postoperative; Receptors, Opioid, kappa | 2021 |
Incidence of Delirium With Different Oral Opioids in Previously Opioid-Naive Patients.
Topics: Analgesics, Opioid; Delirium; Humans; Incidence; Morphine; Oxycodone; Tapentadol | 2022 |
Analgesic Efficacy and Safety of Spinal Oxycodone in Total Hip Arthroplasty: A Preliminary Study.
Topics: Analgesics, Opioid; Arthroplasty, Replacement, Hip; Bupivacaine; Double-Blind Method; Female; Humans; Morphine; Oxycodone; Pain, Postoperative | 2022 |
Tapentadol shows lower intrinsic efficacy at µ receptor than morphine and oxycodone.
Topics: Analgesics, Opioid; Animals; Cell Line, Tumor; Humans; Mice; Morphine; Oxycodone; Receptors, Opioid, mu; Tapentadol | 2022 |
Prevalence of opioid prescriptions in Taiwan (2008-2018).
Topics: Analgesics, Opioid; Chronic Pain; Drug Prescriptions; Humans; Meperidine; Morphine; Neoplasms; Oxycodone; Prevalence; Taiwan; United States | 2022 |
An Evaluation of the Effect of the OxyContin Reformulation on Unintentional Fatal and Nonfatal Overdose.
Topics: Analgesics, Opioid; Drug Overdose; Humans; Morphine; Opioid-Related Disorders; Oxycodone; United States | 2022 |
Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT
Topics: Analgesics, Opioid; Chronic Pain; Codeine; Fentanyl; Humans; MAP Kinase Signaling System; Morphine; Oxycodone; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, mu | 2022 |
Evaluating the population-level effects of oxycodone restrictions on prescription opioid utilization in Ontario.
Topics: Analgesics, Opioid; Drug Prescriptions; Humans; Morphine; Ontario; Opioid-Related Disorders; Oxycodone | 2022 |
Opioid Antagonist Nanodrugs Successfully Attenuate the Severity of Ischemic Stroke.
Topics: Analgesics, Opioid; Animals; Ischemic Stroke; Mice; Morphine; Naloxone; Naltrexone; Nanoparticles; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Stroke; Tight Junction Proteins | 2022 |
Short-term mortality following tramadol poisonings in Denmark.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Denmark; Humans; Morphine; Oxycodone; Tramadol | 2022 |
A Comparison of Institutional Opioid Equianalgesia Tools: A National Study.
Topics: Administration, Oral; Analgesics, Opioid; Fentanyl; Humans; Hydrocodone; Hydromorphone; Levorphanol; Morphine; Oxycodone; Tapentadol; Tramadol | 2022 |
Oxycodone/naloxone versus tapentadol in real-world chronic non-cancer pain management: an observational and pharmacogenetic study.
Topics: Analgesics, Opioid; Cancer Pain; Chronic Pain; Constipation; Delayed-Action Preparations; Drug Combinations; Female; Humans; Morphine; Naloxone; Oxycodone; Pharmacogenomic Testing; Quality of Life; Tapentadol | 2022 |
Prescribing trend of tapentadol in a Sydney local health district.
Topics: Analgesics, Opioid; Australia; Delayed-Action Preparations; Humans; Morphine; Oxycodone; Pain, Postoperative; Phenols; Tapentadol; Tramadol | 2022 |
REL-1017 (esmethadone; D-methadone) does not cause reinforcing effect, physical dependence and withdrawal signs in Sprague Dawley rats.
Topics: Animals; Ketamine; Methadone; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Substance-Related Disorders | 2022 |
Trends in strong opioid prescription for cancer patients in Japan from 2010 to 2019: an analysis with large medical claims data.
Topics: Aged; Analgesics, Opioid; Drug Prescriptions; Fentanyl; Humans; Infant; Japan; Morphine; Neoplasms; Oxycodone; Practice Patterns, Physicians'; Prescriptions | 2022 |
Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns.
Topics: Adult; Analgesics, Opioid; Codeine; Cohort Studies; Female; Humans; Hydrocodone; Hydromorphone; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine; Neonatal Abstinence Syndrome; Oxycodone; Pain; Pregnancy; Prescriptions; Substance Withdrawal Syndrome; Tramadol; United States | 2022 |
The opioid epidemic: A worldwide exploratory study using the WHO pharmacovigilance database.
Topics: Analgesics, Opioid; Bayes Theorem; Codeine; Fentanyl; Humans; Morphine; Opioid Epidemic; Opioid-Related Disorders; Oxycodone; Pharmacovigilance; Tramadol; World Health Organization | 2023 |
Opioid prescriber responsibility: A Danish drug utilization study.
Topics: Analgesics, Opioid; Drug Prescriptions; Drug Utilization; Humans; Morphine; Oxycodone; Practice Patterns, Physicians' | 2023 |
Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Topics: Analgesics, Opioid; Animals; Antibodies, Monoclonal; Mice; Morphine; Nicotine; Oxycodone | 2023 |
Opioids for pain.
Topics: Analgesics, Opioid; Humans; Morphine; Oxycodone; Pain | 2022 |
Comparison table: Some oral/transdermal opioid analgesics.
Topics: Administration, Cutaneous; Analgesics, Opioid; Codeine; Humans; Morphine; Oxycodone | 2022 |
Systemic Opioids for Dyspnea in Cancer Patients: A Real-world Observational Study.
Topics: Adult; Analgesics, Opioid; Drug Tolerance; Dyspnea; Humans; Morphine; Neoplasms; Oxycodone | 2023 |
Endomorphin analog ZH853 shows low reward, tolerance, and affective-motivational signs of withdrawal, while inhibiting opioid withdrawal and seeking.
Topics: Analgesics, Opioid; Animals; Female; Humans; Male; Mice; Morphine; Narcotics; Opioid-Related Disorders; Oxycodone; Rats; Reward; Substance Withdrawal Syndrome | 2023 |
Evidence Regarding Pharmacogenetics in Pain Management and Cancer.
Topics: Analgesics, Opioid; Cancer Pain; Catechol O-Methyltransferase; Cytochrome P-450 CYP2D6; Genotype; Humans; Morphine; Neoplasms; Oxycodone; Pain Management; Pharmacogenetics | 2023 |
The impact of hydrocodone rescheduling on utilization, abuse, misuse, and overdose deaths.
Topics: Analgesics, Opioid; Codeine; Drug Overdose; Heroin; Humans; Hydrocodone; Morphine; Oxycodone; Practice Patterns, Physicians' | 2023 |
Effects of oxycodone pharmacogenetics on postoperative analgesia and related clinical outcomes in children: a pilot prospective study.
Topics: Analgesia; Analgesics, Opioid; Child; Humans; Morphine; Oxycodone; Pain, Postoperative; Pharmacogenetics; Prospective Studies | 2023 |
Do Types of Opioids Matter for Terminal Cancer Dyspnea? A Preliminary Multicenter Cohort Study.
Topics: Aged; Analgesics, Opioid; Cohort Studies; Dyspnea; Humans; Hydromorphone; Morphine; Neoplasms; Oxycodone | 2023 |
Analgesic Effects of Fisetin, Peimine, Astaxanthin, Artemisinin, Bardoxolone Methyl and 740 Y-P and Their Influence on Opioid Analgesia in a Mouse Model of Neuropathic Pain.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Artemisinins; Disease Models, Animal; Hyperalgesia; Male; Mice; Morphine; Neuralgia; NF-E2-Related Factor 2; NF-kappa B; Oxycodone; Phosphatidylinositol 3-Kinases | 2023 |
Oral morphine induces spinal 5-hydroxytryptamine (5-HT) release using an opioid receptor-independent mechanism.
Topics: Analgesics, Opioid; Animals; Morphine; Naloxone; Oxycodone; Pain; Rats; Receptors, Opioid; Serotonin | 2023 |
Assessment of the potential of novel and classical opioids to induce respiratory depression in mice.
Topics: Analgesics, Opioid; Animals; HEK293 Cells; Humans; Male; Methadone; Mice; Morphine; Oxycodone; Respiratory Insufficiency | 2023 |
Differences in severity of poison centers exposures involving XTAMPZA
Topics: Analgesics, Opioid; Delayed-Action Preparations; Humans; Morphine; Opioid-Related Disorders; Oxycodone | 2023 |
Opioid detection in maternal and neonatal hair and meconium: characterization of an at-risk population and implications to fetal toxicology.
Topics: Analgesics, Opioid; Cocaine; Ethanol; Fatty Acids; Female; Fetal Alcohol Spectrum Disorders; Fetus; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Narcotics; Oxycodone; Population Groups; Pregnancy; Pregnancy Complications; Risk; Substance Abuse Detection; Substance-Related Disorders | 2010 |