oxycodone and methylnaltrexone

oxycodone has been researched along with methylnaltrexone in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Kapoor, S1
Leppert, W1
Müller-Lissner, S1
Candy, B; Jones, L; Larkin, PJ; Stone, P; Vickerstaff, V2
Blackney, KA; Edwards, DA; Kamdar, NV; Liu, CA1
Beeker, A; Berkhof, J; Neefjes, ECW; Rhodius, CA; Ten Oever, D; van den Berg, HP; van der Vliet, HJ; van der Vorst, MJDL; van der Wijngaart, H; Verheul, HMW1
Akbarali, HI; Beardsley, PM; Komla, E; Moisa, LT; Mustafa, MA; Poklis, JL; Walentiny, DM1

Reviews

4 review(s) available for oxycodone and methylnaltrexone

ArticleYear
The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review.
    Advances in therapy, 2010, Volume: 27, Issue:10

    Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Laxatives; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds

2010
[Opiate induced constipation--mechanisms, relevance and treatment].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:43

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Constipation; Drug Therapy, Combination; Gastrointestinal Motility; Humans; Laxatives; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds

2013
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
    The Cochrane database of systematic reviews, 2018, 06-05, Volume: 6

    Topics: Constipation; Defecation; Female; Gastrointestinal Agents; Humans; Intestinal Diseases; Male; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Related Disorders; Oxycodone; Palliative Care; Piperidines; Quaternary Ammonium Compounds; Randomized Controlled Trials as Topic; Receptors, Opioid, mu

2018
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
    The Cochrane database of systematic reviews, 2022, 09-15, Volume: 9

    Topics: Adult; Analgesics, Opioid; Child; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Induced Constipation; Oxycodone; Palliative Care; Quaternary Ammonium Compounds; Substance Withdrawal Syndrome

2022

Other Studies

6 other study(ies) available for oxycodone and methylnaltrexone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Emerging new therapeutic options for the management of opioid induced constipation.
    Journal of pain & palliative care pharmacotherapy, 2010, Volume: 24, Issue:1

    Topics: Alprostadil; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Laxatives; Lubiprostone; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds

2010
Methylnaltrexone-Associated Bowel Perforation in Postoperative Opioid-Induced Constipation and Ogilvie Syndrome: A Case Report.
    A&A practice, 2019, Jan-15, Volume: 12, Issue:2

    Topics: Analgesics, Opioid; Colonic Pseudo-Obstruction; Constipation; Decompression, Surgical; Humans; Hydromorphone; Intestinal Perforation; Low Back Pain; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Postoperative Complications; Quaternary Ammonium Compounds; Spinal Stenosis

2019
Optimal treatment of opioid induced constipation in daily clinical practice - an observational study.
    BMC palliative care, 2019, Mar-29, Volume: 18, Issue:1

    Topics: Aged; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Laxatives; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neoplasms; Oxycodone; Pain Management; Prospective Studies; Quaternary Ammonium Compounds; Retrospective Studies; Surveys and Questionnaires

2019
Methylnaltrexone crosses the blood-brain barrier and attenuates centrally-mediated behavioral effects of morphine and oxycodone in mice.
    Neuropharmacology, 2021, 03-01, Volume: 185

    Topics: Analgesics, Opioid; Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Oxycodone; Pain Measurement; Quaternary Ammonium Compounds

2021