oxybutynin and trospium chloride

oxybutynin has been researched along with trospium chloride in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.82)18.2507
2000's17 (50.00)29.6817
2010's14 (41.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Burgdörfer, H; Hachen, HJ; Madersbacher, H; Mürtz, G; Richter, R; Stöhrer, M1
Dimpfel, W; Pietzko, A; Schwantes, U; Topfmeier, P1
Bulitta, M; Burmeister, S; Fröhlich, G; Wiedemann, A1
Appell, RA; Dmochowski, RR1
Dimpfel, W; Todorova, A; Vonderheid-Guth, B1
Hader, C; Keller, T; Welz-Barth, A1
Ballering-Brühl, B; Halaska, M; Höfner, K; Jonas, U; Primus, G; Ralph, G; Wiedemann, A1
Rovner, ES; Wein, AJ1
Rovner, ES1
Sand, PK1
Arold, G; Diefenbach, K; Haselmann, J; Roots, I; Schwantes, U; Wollny, A1
Chancellor, MB; de Miguel, F; Kim, Y; Masuda, H; Yoshimura, N1
Machado, C; Singh-Franco, D; Tuteja, S; Zapantis, A1
Krivoborodov, GG; Mazo, EB1
MacDiarmid, SA; Staskin, DR1
Hegde, SS; Michel, MC1
Chancellor, MB; de Miguel, F1
Amend, B; Hennenlotter, J; Horstmann, M; Schäfer, T; Sievert, KD; Stenzl, A1
MacDiarmid, S; Malhotra, BK; Sandage, BW1
Bödeker, RH; Madersbacher, H; Palmtag, H; Stöhrer, M; Zellner, M1
Bödeker, RH; Madersbacher, H; Neumeister, C; Zellner, M1
Bönisch, H; Geyer, J; Wenge, B1
Schröder, A; Thüroff, JW1
Kane, RL; Ramakrishnan, R; Sainfort, F; Shamliyan, T; Wyman, JF1
Dede, FS; Dede, H; Dolen, İ; Sivaslioglu, AA1
Benbouzid, R; Enjalbert, M; Hadiji, N; Leblond, C; Mieusset, R; Previnaire, JG; Robain, G; Soler, JM1
Kosilov, KV; Kosilova, LV; Krasnykh, MA; Loparev, SA1
Ariogul, S; Cankurtaran, E; Cankurtaran, M; Ergen, A; Esin, E; Halil, M; Kuyumcu, ME; Ozcan, M; Ulger, Z; Yavuz, BB; Yeşil, Y1
Fahmy, A; Mahfouz, W; Mokhless, I; Rhashad, H; Youssif, M1
Hikiyama, E; Ito, Y; Kashiwabara, M; Onoue, S; Yamada, S; Yoshida, A1
Deliktas, H; Gedik, A; Nergis, Y; Orgen, S; Sahin, H1
Cetinel, B; Dincer, M; Gultekin, MH; Guzelsoy, M; Onal, B; Turegun, FA1
Almeida, FG; Bernardo, WM; Sacomani, CAR; Silvinato, A1

Reviews

12 review(s) available for oxybutynin and trospium chloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advancements in pharmacologic management of the overactive bladder.
    Urology, 2000, Dec-04, Volume: 56, Issue:6 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Aged; Animals; Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Benzilates; Benzofurans; Calcium Channel Blockers; Cholinergic Antagonists; Cresols; Delayed-Action Preparations; Drug Administration Routes; Female; Humans; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Muscle Relaxants, Central; Nortropanes; Phenylpropanolamine; Pyrrolidines; Tolterodine Tartrate; Urinary Incontinence

2000
Update on overactive bladder: pharmacologic approaches on the horizon.
    Current urology reports, 2003, Volume: 4, Issue:5

    Topics: Administration, Cutaneous; Administration, Intravesical; Administration, Oral; Adrenergic beta-3 Receptor Antagonists; Benzhydryl Compounds; Benzilates; Benzofurans; Botulinum Toxins; Cresols; Dosage Forms; Dose-Response Relationship, Drug; Drug Compounding; Drug Evaluation; Duloxetine Hydrochloride; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Thiophenes; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder Diseases; Urination Disorders

2003
Trospium chloride in the management of overactive bladder.
    Drugs, 2004, Volume: 64, Issue:21

    Topics: Benzhydryl Compounds; Benzilates; Biological Availability; Cresols; Female; Half-Life; Humans; Male; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Randomized Controlled Trials as Topic; Receptors, Muscarinic; Tissue Distribution; Tolterodine Tartrate; Urinary Incontinence

2004
Elevating our therapeutic expectations in overactive bladder.
    Journal of the American Academy of Nurse Practitioners, 2004, Volume: 16, Issue:10 Suppl

    Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Constipation; Cresols; Delayed-Action Preparations; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Incontinence; Vision Disorders; Xerostomia

2004
Trospium chloride for the treatment of overactive bladder with urge incontinence.
    Clinical therapeutics, 2005, Volume: 27, Issue:5

    Topics: Aging; Area Under Curve; Benzhydryl Compounds; Benzilates; Cholinergic Antagonists; Cresols; Female; Humans; Liver Failure; Male; Mandelic Acids; Metabolic Clearance Rate; Nortropanes; Phenylpropanolamine; Randomized Controlled Trials as Topic; Renal Insufficiency; Tolterodine Tartrate; Urinary Incontinence

2005
[Neurological aspect of the hyperactive urinary bladder syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Volume: 105, Issue:7

    Topics: Benzilates; Brain; Brain Diseases; Cerebrovascular Circulation; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parkinson Disease; Positron-Emission Tomography; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder, Neurogenic

2005
Using anticholinergics to treat overactive bladder: the issue of treatment tolerability.
    The American journal of medicine, 2006, Volume: 119, Issue:3 Suppl 1

    Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cholinergic Antagonists; Cresols; Humans; Mandelic Acids; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence

2006
Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites?
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2

    Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive

2006
Treatment of overactive bladder: selective use of anticholinergic agents with low drug-drug interaction potential.
    Geriatrics, 2007, Volume: 62, Issue:5

    Topics: Benzhydryl Compounds; Benzilates; Cholinergic Antagonists; Cresols; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Tolterodine Tartrate; Urinary Bladder, Overactive

2007
New strategies for medical management of overactive bladder in children.
    Current opinion in urology, 2010, Volume: 20, Issue:4

    Topics: Benzhydryl Compounds; Benzilates; Botulinum Toxins; Child; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Quinuclidines; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder, Overactive; Urination

2010
Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review.
    Annals of internal medicine, 2012, Jun-19, Volume: 156, Issue:12

    Topics: Benzhydryl Compounds; Benzilates; Benzofurans; Comparative Effectiveness Research; Cresols; Female; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quality of Life; Quinuclidines; Randomized Controlled Trials as Topic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Incontinence

2012

Trials

11 trial(s) available for oxybutynin and trospium chloride

ArticleYear
Trospium chloride versus oxybutynin: a randomized, double-blind, multicentre trial in the treatment of detrusor hyper-reflexia.
    British journal of urology, 1995, Volume: 75, Issue:4

    Topics: Adolescent; Adult; Benzilates; Double-Blind Method; Female; Humans; Male; Mandelic Acids; Middle Aged; Nortropanes; Parasympatholytics; Pressure; Reflex, Abnormal; Treatment Outcome; Urinary Bladder; Urination; Urodynamics

1995
[Intravesical instillation of trospium chloride, oxybutynin and verapamil for relaxation of the bladder detrusor muscle. A placebo controlled, randomized clinical test].
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: Adult; Benzilates; Calcium Channel Blockers; Female; Humans; Injections; Male; Mandelic Acids; Muscle Relaxation; Muscle, Smooth; Nortropanes; Parasympatholytics; Single-Blind Method; Urinary Bladder; Urodynamics; Verapamil

1998
Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:6

    Topics: Adult; Benzhydryl Compounds; Benzilates; Central Nervous System; Cresols; Electroencephalography; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Placebos; Tolterodine Tartrate

2001
Controlled, double-blind, multicentre clinical trial to investigate long-term tolerability and efficacy of trospium chloride in patients with detrusor instability.
    World journal of urology, 2003, Volume: 20, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Benzilates; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Mandelic Acids; Middle Aged; Nortropanes; Parasympatholytics; Prospective Studies; Time Factors; Urinary Bladder Diseases; Urinary Incontinence; Urodynamics

2003
Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged > or = 50 years.
    BJU international, 2005, Volume: 95, Issue:3

    Topics: Aged; Benzhydryl Compounds; Benzilates; Cholinergic Antagonists; Cognition; Cresols; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Polysomnography; Sleep, REM; Tolterodine Tartrate

2005
Effective treatment of neurogenic detrusor dysfunction by combined high-dosed antimuscarinics without increased side-effects.
    European urology, 2008, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Benzhydryl Compounds; Benzilates; Cresols; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Spinal Cord Diseases; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Neurogenic; Urodynamics

2008
Trospium chloride and oxybutynin hydrochloride in a german study of adults with urinary urge incontinence: results of a 12-week, multicenter, randomized, double-blind, parallel-group, flexible-dose noninferiority trial.
    Clinical therapeutics, 2009, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzilates; Double-Blind Method; Female; Humans; Male; Mandelic Acids; Middle Aged; Nortropanes; Parasympatholytics; Surveys and Questionnaires; Urinary Incontinence, Urge; Urination; Young Adult

2009
Dose escalation improves therapeutic outcome: post hoc analysis of data from a 12-week, multicentre, double-blind, parallel-group trial of trospium chloride in patients with urinary urge incontinence.
    BMC urology, 2010, Sep-14, Volume: 10

    Topics: Adolescent; Adult; Aged; Benzilates; Double-Blind Method; Female; Humans; Male; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Time Factors; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Xerostomia; Young Adult

2010
What is the success of drug treatment in urge urinary incontinence? What should be measured?
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:3

    Topics: Adult; Benzhydryl Compounds; Benzilates; Cresols; Female; Humans; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Quality of Life; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Urodynamics

2013
[Treatment of overactive bladder in older women increased doses of antimuscarinic drugs safe and effective alternative to existing methods].
    Advances in gerontology = Uspekhi gerontologii, 2014, Volume: 27, Issue:1

    Topics: Aged; Benzhydryl Compounds; Benzilates; Cresols; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Female; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Overactive; Urinary Incontinence, Urge; Urodynamics

2014
Which antimuscarinic agents used in the treatment of overactive bladder increase heart rate? a prospective randomized clinical trial.
    International urology and nephrology, 2019, Volume: 51, Issue:3

    Topics: Adult; Aged; Benzhydryl Compounds; Benzilates; Benzofurans; Blood Pressure; Female; Heart Rate; Humans; Male; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Nortropanes; Prospective Studies; Pyrrolidines; Solifenacin Succinate; Tolterodine Tartrate; Urinary Bladder, Overactive

2019

Other Studies

11 other study(ies) available for oxybutynin and trospium chloride

ArticleYear
Influences of trospium chloride and oxybutynin on quantitative EEG in healthy volunteers.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:4

    Topics: Adult; Benzilates; Brain Mapping; Electroencephalography; Eye Movements; Heart Rate; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Psychometrics; Volunteers

1994
[Urinary incontinence--treatment].
    Deutsche medizinische Wochenschrift (1946), 2003, Apr-04, Volume: 128, Issue:14

    Topics: Adrenergic Uptake Inhibitors; Behavior Therapy; Benzhydryl Compounds; Benzilates; Biofeedback, Psychology; Cholinergic Antagonists; Contraindications; Cresols; Deamino Arginine Vasopressin; Electric Stimulation Therapy; Female; Humans; Imipramine; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Parasympatholytics; Phenylpropanolamine; Physical Therapy Modalities; Renal Agents; Tolterodine Tartrate; Urinary Incontinence; Urinary Incontinence, Stress

2003
Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways.
    Urology, 2005, Volume: 65, Issue:2

    Topics: Acetylcholine; Administration, Intravesical; Afferent Pathways; Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Dimethindene; Female; Infusions, Parenteral; Instillation, Drug; Mandelic Acids; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nortropanes; Phenylpropanolamine; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tolterodine Tartrate; Urinary Bladder; Urodynamics

2005
The effects of reformulation: improved therapeutic index.
    Current urology reports, 2008, Volume: 9, Issue:6

    Topics: Benzhydryl Compounds; Benzilates; Chemistry, Pharmaceutical; Cresols; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Tolterodine Tartrate; Urinary Bladder, Overactive

2008
Oxybutynin and trospium are substrates of the human organic cation transporters.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:2

    Topics: Benzilates; Binding, Competitive; Cell Culture Techniques; HEK293 Cells; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Substrate Specificity; Transfection

2011
Are oxybutynin and trospium efficacious in the treatment of detrusor overactivity in spinal cord injury patients?
    Spinal cord, 2014, Volume: 52, Issue:9

    Topics: Adult; Benzilates; Female; Humans; Male; Mandelic Acids; Nortropanes; Retrospective Studies; Spinal Cord Injuries; Time Factors; Treatment Outcome; Urinary Bladder, Overactive; Urodynamics; Urological Agents

2014
Influence of antimuscarinic therapy on cognitive functions and quality of life in geriatric patients treated for overactive bladder.
    Aging & mental health, 2015, Volume: 19, Issue:3

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Benzhydryl Compounds; Benzilates; Benzofurans; Cognition Disorders; Cresols; Depression; Female; Follow-Up Studies; Geriatric Assessment; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Phenylpropanolamine; Pyrrolidines; Quality of Life; Tolterodine Tartrate; Treatment Outcome; Urinary Bladder, Overactive

2015
Combined low-dose antimuscarinics for refractory detrusor overactivity in children.
    Journal of pediatric urology, 2016, Volume: 12, Issue:4

    Topics: Benzilates; Child; Drug Therapy, Combination; Female; Humans; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Prospective Studies; Urinary Bladder, Overactive

2016
Muscarinic Receptor Binding in Rat Bladder Urothelium and Detrusor Muscle by Intravesical Solifenacin.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:7

    Topics: Administration, Intravesical; Animals; Benzilates; Male; Mandelic Acids; Muscarinic Antagonists; Muscle, Smooth; Nortropanes; Rats, Sprague-Dawley; Receptors, Muscarinic; Solifenacin Succinate; Urinary Bladder; Urological Agents; Urothelium

2016
Histopathologic and Urodynamic Effects of the Anticholinergic Drugs Oxybutynin, Tolterodine, and Trospium on the Bladder.
    Lower urinary tract symptoms, 2017, Volume: 9, Issue:1

    Topics: Animals; Benzilates; Male; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Rabbits; Random Allocation; Tolterodine Tartrate; Urinary Bladder; Urological Agents; Urothelium

2017
Overactive bladder - pharmacological treatment.
    Revista da Associacao Medica Brasileira (1992), 2019, May-02, Volume: 65, Issue:4

    Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Antidepressive Agents; Benzilates; Benzofurans; Brazil; Clinical Decision-Making; Drug Therapy, Combination; Humans; Mandelic Acids; Muscarinic Antagonists; Nortropanes; Pyrrolidines; Solifenacin Succinate; Thiazoles; Tolterodine Tartrate; Urinary Bladder, Overactive

2019