oxybutynin and donepezil

oxybutynin has been researched along with donepezil in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's9 (69.23)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Axelrod, S; Bielory, L1
Cun, D; Fang, L; Liu, N; Quan, P; Zhang, Y1
Argade, NS; Dua, K; Madan, JR1
Bae, KS; Choi, HY; Choi, YK; Hong, D; Jeon, HS; Kim, SS; Kim, YH; Lee, SH; Lim, HS1
Bae, KS; Choi, HY; Hong, D; Kim, SS; Kim, YH; Lim, HS1
Deardorff, WJ; Grossberg, GT1
Arfi, S; Bhatta, RS; Mishra, PR; Mittapelly, N; Pandey, G; Tulsankar, SL1
Cha, K-; Choi, WS; Jang, SW; Kim, HJ; Kim, HS; Shin, CY; Sohn, UD1
Larkin, HD1

Reviews

2 review(s) available for oxybutynin and donepezil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacotherapeutic strategies in the treatment of severe Alzheimer's disease.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:13

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Humans; Indans; Memantine; Piperidines; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Transdermal Patch

2016

Trials

2 trial(s) available for oxybutynin and donepezil

ArticleYear
Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Administration, Cutaneous; Adult; Chromatography, Liquid; Donepezil; Drug Tolerance; Healthy Volunteers; Humans; Indans; Male; Middle Aged; Piperidines; Single-Blind Method; Tandem Mass Spectrometry; Transdermal Patch; Young Adult

2015
Therapeutic dosage assessment based on population pharmacokinetics of a novel single-dose transdermal donepezil patch in healthy volunteers.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Adult; Cholinesterase Inhibitors; Donepezil; Healthy Volunteers; Humans; Indans; Male; Models, Biological; Piperidines; Transdermal Patch; Young Adult

2015

Other Studies

9 other study(ies) available for oxybutynin and donepezil

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Beta2-agonists and paresthesias in multiple sclerosis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2007, Volume: 98, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Amantadine; Analgesics, Non-Narcotic; Androstadienes; Aromatase Inhibitors; Asthma; Bronchodilator Agents; Donepezil; Drug Therapy, Combination; Female; Fluticasone; Food Hypersensitivity; Humans; Indans; Interferons; Latex Hypersensitivity; Letrozole; Mandelic Acids; Middle Aged; Multiple Sclerosis; Nebulizers and Vaporizers; Nitriles; Nootropic Agents; Parasympatholytics; Paresthesia; Piperidines; Respiratory Function Tests; Salmeterol Xinafoate; Thyroxine; Triazoles

2007
Effect of backing films on the transdermal delivery of donepezil from patches.
    AAPS PharmSciTech, 2014, Volume: 15, Issue:6

    Topics: Administration, Cutaneous; Animals; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Donepezil; Excipients; Indans; Kinetics; Permeability; Pilot Projects; Piperidines; Rabbits; Skin; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Transdermal Patch; Water

2014
Formulation and evaluation of transdermal patches of donepezil.
    Recent patents on drug delivery & formulation, 2015, Volume: 9, Issue:1

    Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Donepezil; Drug Evaluation, Preclinical; Indans; Piperidines; Rats; Skin Absorption; Transdermal Patch

2015
In Depth Analysis of Pressure-Sensitive Adhesive Patch-Assisted Delivery of Memantine and Donepezil Using Physiologically Based Pharmacokinetic Modeling and in Vitro/in Vivo Correlations.
    Molecular pharmaceutics, 2018, 07-02, Volume: 15, Issue:7

    Topics: Administration, Cutaneous; Alzheimer Disease; Animals; Biological Availability; Donepezil; Drug Delivery Systems; Drug Liberation; Excipients; Memantine; Models, Animal; Models, Biological; Nootropic Agents; Pressure; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Transdermal Patch

2018
Pharmacological evaluation and safety of a donepezil patch.
    Die Pharmazie, 2020, 12-01, Volume: 75, Issue:12

    Topics: Administration, Cutaneous; Animals; Cholinesterase Inhibitors; Donepezil; Humans; Male; Rabbits; Rats; Skin; Swine; Swine, Miniature; Transdermal Patch

2020
First Donepezil Transdermal Patch Approved for Alzheimer Disease.
    JAMA, 2022, 05-03, Volume: 327, Issue:17

    Topics: Administration, Cutaneous; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Nootropic Agents; Rivastigmine; Transdermal Patch

2022