Compounds > oxybutynin

oxybutynin and caffeine

oxybutynin has been researched along with caffeine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cole, L; Heard, C1
Caffarel-Salvador, E; Donnelly, RF; McCarthy, HO; McElnay, JC; Mooney, K; Tuan-Mahmood, TM; Woolfson, AD1
Dangol, M; Fakhraei Lahiji, S; Huh, I; Jang, M; Jung, H; Kim, S; Li, CG; Ma, Y1

Reviews

1 review(s) available for oxybutynin and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for oxybutynin and caffeine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Skin permeation enhancement potential of Aloe Vera and a proposed mechanism of action based upon size exclusion and pull effect.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Aloe; Animals; Caffeine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Colchicine; Diffusion Chambers, Culture; Drug Carriers; Excipients; Gels; Mandelic Acids; Mefenamic Acid; Molecular Weight; Organ Culture Techniques; Permeability; Plant Extracts; Quinine; Skin; Skin Absorption; Solubility; Swine; Time Factors; Water

2007
Potential of hydrogel-forming and dissolving microneedles for use in paediatric populations.
    International journal of pharmaceutics, 2015, Jul-15, Volume: 489, Issue:1-2

    Topics: Administration, Cutaneous; Adolescent; Analgesics; Animals; Caffeine; Child; Female; Humans; Hydrogels; Lidocaine; Male; Microinjections; Needles; Pain; Pediatrics; Physicians; Public Opinion; Rats, Sprague-Dawley; Skin; Swine; Transdermal Patch

2015
Anti-obesity effect of a novel caffeine-loaded dissolving microneedle patch in high-fat diet-induced obese C57BL/6J mice.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, Nov-10, Volume: 265

    Topics: Administration, Cutaneous; Animals; Anti-Obesity Agents; Caffeine; Cell Survival; Cholesterol; Diet, High-Fat; Drug Delivery Systems; Excipients; Female; HEK293 Cells; Humans; Hyaluronic Acid; Lipoproteins, HDL; Materials Testing; Mice; Mice, Inbred C57BL; Mice, Obese; Microinjections; Needles; Obesity; Polymers; Skin; Transdermal Patch; Triglycerides; Weight Loss

2017