oxprenolol and timolol

oxprenolol has been researched along with timolol in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (50.00)	18.7374
1990's	7 (15.91)	18.2507
2000's	10 (22.73)	29.6817
2010's	5 (11.36)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Caron, G; Ermondi, G	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Bard, B; Carrupt, PA; Martel, S	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Bellman, K; Knegtel, RM; Settimo, L	1
Meier, J	1
Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ	1
Bühler, FR; Burkart, F; Marbet, G; Patel, U	1
Kiechel, JR; Meier, J	1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S	1
Brown, B; Buckley, M; Darragh, A; Fitzgerald, D; Foley, JE; O'Kelly, D; Tormey, W; Vukovich, RA; Willard, DA	1
Hansen, JE; Kayser, L; Perrild, H; Petersen, PH; Skovsted, L	1
Basciu, M; Cherchi, A; Pili, G; Sau, F; Seguro, C; Siddi, PP; Tamponi, R	1
Sun, ZP; Zhou, Y	1
Akritopoulos, P; Petounis, AD	1
Fishbein, L; Jackson, CD	1
Halawa, B; Mazurek, W	1
al-Gohary, O; Lyal, J; Murray, JB	1
Hampton, JR	1
Le Douarec, JC; Lotti, VJ; Schmitt, C	1
Amery, A; Bulpitt, C; Cattaert, A; Fagard, R; Staessen, J; Vanhees, L	1
Ermakova, VN	1
Weisswange, A	1
Friedewald, WT; Frishman, WH; Furberg, CD	2
Chung, DC; Laschuk, MJ	1
Abed, J; Donaldson, R; Nashat, F; Taggart, P	1
Rose, G	1
Grignolo, A; Koepke, JP; Light, KC; Obrist, PA	1
De Swiet, M; Fidler, J; Smith, V	1
Gemba, M; Hosaka, K; Kamiyama, M; Kobayashi, I; Konno, C; Maruo, H; Ueno, T	1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R	1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA	1
Akesolo, U; Alonso, RM; Jiménez, RM; Maguregui, MI	1
Banga, AK; Betageri, GV; Chaturvedula, A; Conjeevaram, R; Sunkara, G	1

Reviews

7 review(s) available for oxprenolol and timolol

Article	Year
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Jan-01, Volume: 39, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol	1986
The use of beta blockers for the reduction of mortality after myocardial infarction. European heart journal, 1981, Volume: 2, Issue:4 Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol	1981
Beta-adrenergic blockade for survivors of acute myocardial infarction. The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol	1984
The new beta-adrenergic antagonists. Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4 Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol	1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984

Trials

8 trial(s) available for oxprenolol and timolol

Article	Year
Effect of beta-blockers on exercise double product (systolic blood pressure x heart rate). British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Drug Evaluation; Heart Rate; Humans; Kinetics; Male; Middle Aged; Oxprenolol; Physical Exertion; Pindolol; Propanolamines; Propranolol; Time Factors; Timolol	1979
[Electrocardiographic and echocardiographic changes during antihypertensive therapy]. Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:12 Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidone; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Indenes; Male; Middle Aged; Nifedipine; Oxprenolol; Pindolol; Propanolamines; Timolol	1990
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Jan-01, Volume: 39, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol	1986
The use of beta blockers for the reduction of mortality after myocardial infarction. European heart journal, 1981, Volume: 2, Issue:4 Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol	1981
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients. American heart journal, 1982, Volume: 104, Issue:6 Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol	1982
[Improved prognosis using beta blockers after myocardial infarct?]. Lebensversicherungs Medizin, 1984, Jan-01, Volume: 36, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Prognosis; Propranolol; Sotalol; Timolol	1984
Beta-adrenergic blockade for survivors of acute myocardial infarction. The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol	1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984

Other Studies

33 other study(ies) available for oxprenolol and timolol

Article	Year
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1977, Volume: 606 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol	1977
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol	1978
Renin-suppressive potency of various beta-adrenergic blocking agents at supine rest and during upright exercise. Clinical science and molecular medicine. Supplement, 1975, Volume: 2 Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Male; Oxprenolol; Physical Exertion; Pindolol; Posture; Practolol; Propranolol; Renin; Timolol	1975
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol	1979
Acute beta-blockade changes the extracellular distribution of thyroid hormones. Journal of endocrinological investigation, 1990, Volume: 13, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; alpha-Macroglobulins; Carrier Proteins; Female; Humans; Male; Membrane Proteins; Middle Aged; Oxprenolol; Pindolol; Serum Albumin; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Thyroxine; Timolol; Tissue Distribution; Triiodothyronine	1990
[Resolution of the enantiomers of some beta-amino alcohols using chiral derivatization and reversed-phase liquid chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:4 Topics: Chromatography, High Pressure Liquid; Oxprenolol; Phenylephrine; Propafenone; Stereoisomerism; Timolol	1990
Influence of topical and systemic beta-blockers on tear production. International ophthalmology, 1989, Volume: 13, Issue:1-2 Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Butoxamine; Drug Administration Routes; Injections, Intramuscular; Lacrimal Apparatus; Male; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Rabbits; Time Factors; Timolol	1989
Adsorption of antihypertensives by suspensoids. Part 2. The adsorption of acebutolol, metoprolol, nadolol, oxprenolol, and timolol by attapulgite, charcoal, kaolin and magnesium trisilicate. Pharmaceutica acta Helvetiae, 1988, Volume: 63, Issue:1 Topics: Acebutolol; Adsorption; Antihypertensive Agents; Charcoal; Kaolin; Magnesium; Magnesium Compounds; Magnesium Silicates; Metoprolol; Nadolol; Oxprenolol; Silicic Acid; Silicon; Silicon Compounds; Timolol	1988
Penetration of five beta-adrenergic antagonists into the rabbit eye after ocular instillation. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 217, Issue:3 Topics: Administration, Topical; Adrenergic beta-Agonists; Alprenolol; Animals; Aqueous Humor; Chromatography, Gas; Oxprenolol; Practolol; Propranolol; Rabbits; Timolol	1981
[Effect of beta-adrenoblockers on prostaglandin-induced ocular hypertension in rabbits]. Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:10 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Dinoprostone; Male; Ocular Hypertension; Oxprenolol; Propanolamines; Propranolol; Prostaglandins E; Rabbits; Timolol	1983
Class III action of beta-blocking agents. Cardiovascular research, 1984, Volume: 18, Issue:11 Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart; Heart Ventricles; Male; Nadolol; Oxprenolol; Pindolol; Propanolamines; Propranolol; Sotalol; Timolol	1984
Beta-blockers after myocardial infarction. Australian and New Zealand journal of medicine, 1984, Volume: 14, Issue:4 Topics: Adrenergic beta-Antagonists; Humans; Myocardial Infarction; Oxprenolol; Propranolol; Timolol	1984
Central beta adrenoceptor mediation of the antinatriuretic response to behavioral stress in conscious dogs. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1 Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Conditioning, Psychological; Consciousness; Dogs; Male; Natriuresis; Oxprenolol; Propranolol; Receptors, Adrenergic, beta; Stress, Physiological; Timolol	1983
Excretion of oxprenolol and timolol in breast milk. British journal of obstetrics and gynaecology, 1983, Volume: 90, Issue:10 Topics: Adult; Female; Humans; Hypertension; Infant, Newborn; Milk, Human; Oxprenolol; Timolol	1983
Relationship between amount of beta-blockers permeating through the stratum corneum and skin irritation after application of beta-blocker adhesive patches to guinea pig skin. Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4 Topics: Acebutolol; Administration, Cutaneous; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dermatitis, Irritant; Guinea Pigs; Male; Oxprenolol; Skin; Skin Absorption; Timolol	1997
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions. Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2 Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol	1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol	1998
Quantitative determination of oxprenolol and timolol in urine by capillary zone electrophoresis. Journal of chromatography. A, 2002, Mar-08, Volume: 949, Issue:1-2 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Electrophoresis, Capillary; Humans; Oxprenolol; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Timolol	2002
Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation. Pharmaceutical research, 2003, Volume: 20, Issue:9 Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Animals; Biological Transport; Chromatography, High Pressure Liquid; Drug Carriers; Injections, Intravenous; Iontophoresis; Irritants; Liposomes; Metoprolol; Oxprenolol; Propranolol; Rats; Skin; Skin Absorption; Sotalol; Stereoisomerism; Timolol	2003