oxophenylarsine has been researched along with arsenic in 529 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (9.83) | 18.7374 |
| 1990's | 226 (42.72) | 18.2507 |
| 2000's | 180 (34.03) | 29.6817 |
| 2010's | 64 (12.10) | 24.3611 |
| 2020's | 7 (1.32) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, LC; Autero, M; Mustelin, T; Oetken, C; Ruutu, T; von Willebrand, M | 1 |
| Bernlohr, DA; Shekels, LL; Smith, AJ; Van Etten, RL | 1 |
| Adamczewski, M; Kinet, JP; Paolini, R | 1 |
| Bos, JL; Burgering, BM; Clark, R; McCormick, F; Medema, RH; Pronk, GJ | 1 |
| Leader, NK; Roberts, MH; Towles, JA | 1 |
| Liao, F; Rhee, SG; Shin, HS | 1 |
| Bernardi, P | 1 |
| Grasso, P; Reichert, LE; Santa-Coloma, TA | 1 |
| Fominaya, JM; Hofsteenge, J | 1 |
| Dray, A; Patel, IA; Perkins, MN; Rueff, A; Urban, L | 1 |
| Ecke, M; Gerisch, G; Mihalache, O; Schweiger, A | 1 |
| Fuwa, T; Hanano, M; Ichikawa, M; Kato, Y; Sato, H; Sawada, Y; Sugiyama, Y; Suzuki, H | 1 |
| Clark, AE; Harrison, R; Holman, GD; Kozka, IJ; Yang, J | 1 |
| Hoffman, RD; Lane, MD | 1 |
| Hascall, VC; Takeuchi, Y; Yanagishita, M | 1 |
| Berleth, ES; Braunscheidel, JA; Graziani, LA; Grill, SP; Kasperek, EM; Pickart, CM | 1 |
| Alengrin, F; Ballotti, R; Chauvel, A; Filloux, C; Scimeca, JC; Tartare, S; Van Obberghen, E | 1 |
| Garcia-Morales, P; Klausner, RD; Luong, E; Minami, Y; Samelson, LE | 1 |
| Moss, AL; Ward, WF | 1 |
| Davis, JP; Van Etten, RL; Zhang, ZY | 1 |
| Bernardi, P; Colonna, R; Szabó, I; Vassanelli, S; Veronese, P; Zoratti, M | 1 |
| Boggs, KP; Buse, MG; Dutton, SL; Robinson, KA; Sowell, MO | 1 |
| Hoffman, RD; Lane, MD; Liao, K | 1 |
| Levine, L | 1 |
| Auguet, M; Braquet, P; Chabrier, PE; Delaflotte, S; Guillon, JM | 1 |
| Gudz', TI; Kudriashov, IuB; Kushnareva, IuE; Novgorodov, SA; Zorov, DB | 1 |
| Alexander, RW; Clark, M; Griendling, KK; Lassègue, B | 1 |
| Azzone, GF; Bernardi, P; Lenartowicz, E | 1 |
| Henriksen, EJ | 1 |
| Bos, JL; Burgering, BM; Medema, RH | 1 |
| Hah, JS; Jhun, BH; Jung, CY | 1 |
| Fischer, Y; Kammermeier, H; Rose, H | 1 |
| Balla, T; Baukal, AJ; Catt, KJ; Hunyady, L; Merelli, F | 1 |
| Sato, H; Terasaki, T; Tsuji, A; Yoshioka, K | 1 |
| Hsieh, CH; Wang, C; Wu, WG | 1 |
| Alexander, J; Craven, CM; Kaplan, J; Lamb, J; Sturrock, A | 1 |
| Ganapathy, V; Kulanthaivel, P; Leibach, FH; Mahesh, VB; Simon, BJ | 1 |
| Chauncey, B; Goldstein, L; Kinne, RK; Musch, MW; Schmid, EC | 1 |
| Douen, AG; Jones, MN | 4 |
| Flores-Riveros, JR; Hoffman, RD; Hresko, RC; Lane, MD | 1 |
| Henriksen, EJ; Holloszy, JO | 1 |
| Capeau, J; Caron, M; Cherqui, G; Melin, B; Picard, J; Reynet, C; Wicek, D | 1 |
| Cardemil, E; Encinas, MV; Jabalquinto, AM | 1 |
| Frost, SC; Schwalbe, MS | 1 |
| Bui, D; Christophe, J; Dupuche, MH; Lambert, M; Svoboda, M | 1 |
| Gudz, TI; Kudrjashov, YB; Kushnareva, YE; Novgorodov, SA; Zorov, DB | 1 |
| Ball, D; Elliott, ME; Goodfriend, TL; Siebers, MJ | 1 |
| Altin, JG; Bradshaw, RA | 1 |
| Imanaka, T; Mineo, C; Takano, T; Yagyu, Y | 1 |
| Kaplan, J; Ward, DM; Wiley, HS | 1 |
| Bernier, M; Laird, DM; Lane, MD | 2 |
| Gibson, AE; Herlihy, JT; Noel, RJ; Ward, WF | 1 |
| Ganapathy, V; Leibach, FH; Miyamoto, Y; Tiruppathi, C | 1 |
| Hirai, K; Kang, YS; Sato, H; Terasaki, T; Tsuji, A | 1 |
| Gibbs, EM; Gould, GW; Lienhard, GE; Tanner, LI | 1 |
| Pasternak, CA; Warren, AP | 1 |
| Wheeler, TJ | 2 |
| Capeau, J; Caron, M; Cherqui, G; Picard, J; Wicek, D | 1 |
| Frost, SC; Gibbs, EM; Lane, MD | 1 |
| Frost, SC; Pettengell, K | 1 |
| Alexander, RW; Delafontaine, P; Gimbrone, MA; Griendling, KK; Rittenhouse, SE | 1 |
| Hanahan, DJ; Olson, MS; Saito, K; Steinhelper, ME; Sugatani, J | 1 |
| Biessen, EA; Horn, AS; Norder, JA; Robillard, GT | 1 |
| Bradshaw, RA; Eveleth, DD | 1 |
| Arcuri, KE; Napier, MA; Vandlen, RL | 1 |
| Feldman, RD; Lai, C; McArdle, W | 1 |
| Olson, MS; Steinhelper, ME | 2 |
| Alvear, M; Cardemil, E; Jabalquinto, AM | 1 |
| Berden, JA; Persson, B; Rydström, J; van Dam, K | 1 |
| Buse, MG; Robinson, KA; Sowell, MO | 1 |
| Coulter, SJ; Hertel, C; Perkins, JP | 1 |
| Arnaud, CD; Nyiredy, KO; Silve, CM; Teitelbaum, AP | 1 |
| Fishman, PH; Kassis, S; Olasmaa, M; Sullivan, M | 1 |
| Crews, FT; Kalberg, CJ; Myers, LM; Raizada, MK; Rueth, SM; Sumners, C | 1 |
| Deshusses, J; Nobile, S | 1 |
| Douen, AG; Jones, MN; Kacem, R | 1 |
| Carone, FA; Christensen, EI; Flouret, G; Nakamura, S; Punyarit, P | 1 |
| Burgess, AW; Walker, F | 1 |
| Eckel, J; Reinauer, H | 1 |
| Frost, SC; Kohanski, RA; Lane, MD | 1 |
| Diwan, JJ; Haley, T; Moore, C | 1 |
| Diwan, JJ; Haley, T; Moore, C; Srivastava, J | 1 |
| Brown, JM; Bump, EA; Jacobs, GP; Lee, WW | 1 |
| Frost, SC; Lane, MD | 1 |
| Kitabchi, AE; Stentz, FB | 1 |
| Devaskar, SU; Karycki, L | 1 |
| Hughes, JB; Joshi, S | 1 |
| Cunningham, DD; Wiley, HS | 1 |
| Neuhaus, JM; Wright, JK | 1 |
| Baker, DH; Czarnecki, GL; Garst, JE | 1 |
| Konings, WN; Robillard, GT | 1 |
| Hatefi, Y; Phelps, DC | 1 |
| Hughes, JB; Joshi, S; Sanadi, DR | 1 |
| Doklea, E; Fichtl, B; Forth, W; Liebl, B; Mückter, H; Reichl, FX | 1 |
| Li, J; Pickart, CM | 1 |
| Anel, A; Kleinfeld, AM; Richieri, GV | 1 |
| Biegelmann, E; Gerisch, G; Humbel, B; Jungbluth, A; Schweiger, A; von Arnim, V | 1 |
| Connern, CP; Halestrap, AP | 1 |
| Bunnett, NW; Garland, AM; Grady, EF; Payan, DG; Vigna, SR | 1 |
| Bottari, SP; Brechler, V; De Gasparo, M; Levens, NR | 1 |
| Blaser, K; Green, DR; Simon, HU; Yousefi, S | 1 |
| Le Cabec, V; Maridonneau-Parini, I | 1 |
| Gergely, J; Rozsnyay, Z; Sarmay, G | 2 |
| Doklea, E; Fichtl, B; Forth, W; Liebl, B; Mückter, H | 2 |
| Asselin, J; Schieven, GL; Watson, SP; Yanaga, F | 1 |
| Anel, A; Kleinfeld, AM; Mescher, MF | 1 |
| Hsu, D; Jhun, BH; Maegawa, H; Milarski, KL; Olefsky, JM; Reichart, DR; Saltiel, AR; Seely, BL; Staubs, PA | 1 |
| Kussmann, M; Przybylski, M | 1 |
| Ayuso, MS; Butta, N; Parrilla, R; Urcelay, E | 1 |
| Schwartz, CF | 1 |
| Fletcher, MC; June, CH; Samelson, LE | 1 |
| Johnston, RB; Kawai, K; Kutsumi, H; Rokutan, K | 1 |
| Aggarwal, BB; Singh, S | 1 |
| Chiara, MD; Conde, M; Pintado, E; Sobrino, F | 1 |
| Grasso, P; Leng, N; Reichert, LE | 1 |
| Azevedo, JL; Carey, JO; Dohm, GL; Morris, PG; Pories, WJ | 1 |
| De Potter, WP; Llona, I; Wang, JM | 1 |
| Sakuta, H | 2 |
| Hunt, CA; Weiss, TL; Wu-Pong, S | 1 |
| Greenwalt, DE; Tandon, NN | 1 |
| Brant, WO; Bunnett, NW; Grady, EF; Payan, DG; Slice, LW; Walsh, JH | 1 |
| Chiang, TM | 1 |
| Fisher, S; Marie-Cardine, A; Mustelin, T; Oetken, C; Pessa-Morikawa, T; Ståhls, A; von Willebrand, M | 1 |
| Begum, N | 1 |
| Durrer, P; Richter, C; Schweizer, M | 1 |
| Báez, I; Breithaupt, TB; Eylar, EH; Molina, C; Rivera-Quiñones, C | 1 |
| Aussel, C; Bernard, A; Breittmayer, JP; Deckert, M | 1 |
| Cooper, JA; Durden, DL; Michel, BR; Rosen, H | 1 |
| Kumada, T; Miyata, H; Nakashima, S; Nozawa, Y | 1 |
| Burger, MM; Gitler, C; Schaefer, T; Wiedemann, C | 1 |
| Linas, SL; Schelling, JR | 1 |
| Chabry, J; Gully, D; Kitabgi, P; Labbé-Jullié, C; Mazella, J; Vincent, JP | 1 |
| Deuticke, B; Fischer, Y; Kammermeier, H; Rose, H; Thomas, J | 1 |
| Klein, H; Probst, I; Quentmeier, A; Unthan-Fechner, K | 1 |
| Farber, JL; Hoek, JB; Pastorino, JG; Serroni, A; Snyder, JW | 1 |
| Bajpai, A; Brahmi, Z | 1 |
| Bradley, JR; Johnson, DR; Pober, JS | 1 |
| Anel, A; Kleinfeld, AM | 1 |
| Carter, NS; Fairlamb, AH | 1 |
| Henriksen, EJ; Ritter, LS; Schneider, MC | 1 |
| Fichtl, B; Hunder, G; Nguyen, PT; Schümann, K | 1 |
| Kitagawa, M; Miyahara, M; Mukai, H; Ono, Y; Shibata, H; Shimakawa, M; Takanaga, H | 1 |
| Aboulafia, J; Kanashiro, CA; Paiva, AC; Paiva, TB; Prioste, RN; Shimuta, SI | 1 |
| Chap, H; Planat, V; Record, M; Ribbes, G; Tronchere, H | 1 |
| Pafford, CM; Simples, JE; Strong, JA | 1 |
| Saito, Y; Takagi, J | 1 |
| Belenguer, P; Ducommun, B; Hoffmann, I; Leroy, D; Oustrin, ML | 1 |
| Barzon, E; Bindoli, A; Rigobello, MP | 1 |
| Endo, N; Huang, Z; Leu, CT; Opas, EE; Ramachandaran, C; Rodan, GA; Rodan, SB; Rutledge, SJ; Schmidt, A; Tanaka, H; Wesolowski, G | 1 |
| Currie, RA; Nakshatri, H | 1 |
| Dong, J; Ksenzenko, MY; Rosen, BP; Scott, RA; Shi, W | 1 |
| Busse, R; Fisslthaler, B; Fleming, I | 1 |
| Berleth, ES; Pickart, CM | 1 |
| Bernardi, P; Chernyak, BV; Costantini, P; Petronilli, V | 1 |
| Burger, MM; Schäfer, T; Wiedemann, C | 1 |
| Hoffman, JF; Linderman, JJ; Omann, GM | 1 |
| Aponte, G; Böhm, SK; Bunnett, NW; Grady, EF; Khitin, LM; Payan, DG | 1 |
| Elberg, G; Li, J; Shechter, Y | 1 |
| Bernardi, P; Chernyak, BV | 1 |
| Balsamo, J; Ernst, H; Hoffman, S; Leung, T; Lilien, J; Zanin, MK | 1 |
| Crain, RC; Ling, W; Lynes, MA; Tibbetts, DJ | 1 |
| Marrero, MB; Venema, RC; Venema, VJ | 1 |
| Adamson, RH | 1 |
| Haba, M; Urano, K; Watanabe, J; Yuasa, H | 1 |
| Kumada, T; Miyata, H; Nakamura, Y; Nakashima, S; Nozawa, Y | 1 |
| Abd-Elfattah, AS; Taher, MM | 1 |
| Ballmer-Hofer, K; Meili, R | 1 |
| Baluk, P; Bunnett, NW; Gamp, PD; Grady, EF; Jones, E; McDonald, DM; Payan, DG | 1 |
| Massari, S | 1 |
| Gonzalez De La Fuente, P; Marthan, R; Savineau, JP | 1 |
| Barry, ST; Critchley, DR; Defilippi, P; Retta, SF; Silengo, L; Tarone, G | 1 |
| Lu, X; Oppedijk, BJ; Schilperoort, RA; Van Duijn, B; Wang, M | 1 |
| Connern, CP; Halestrap, AP; Woodfield, KY | 1 |
| Choquet, D; Felsenfeld, DP; Sheetz, MP | 1 |
| Dème, D; Dupuy, C; Gorin, Y; Leseney, AM; Ohayon, R; Pommier, J; Virion, A | 1 |
| Castilho, RF; Kowaltowski, AJ; Vercesi, AE | 1 |
| Rieber, M; Rieber, MS | 1 |
| Bos, JL; Clark, R; de Vries-Smits, AM; McCormick, F; Medema, JP; Pronk, GJ | 1 |
| Alnemri, ES; Earnshaw, WC; Fernandes-Alnemri, T; Goldschmidt-Clermont, PJ; Nakajima, K; Poirier, GG; Sasada, M; Takahashi, A; Yoshizawa-Kumagaya, K | 1 |
| Amatore, C; Arbault, S; Best-Belpomme, M; Pantano, P; Sarasin, A; Sojic, N; Vuillaume, M | 1 |
| Caro, MC; Jiménez, E; Montiel, M | 1 |
| Canet, E; De Nadaï, J; Le Cabec, V; Lonchampt, M; Maridonneau-Parini, I; Roussin, A | 1 |
| Doré, S; Kar, S; Quirion, R | 1 |
| Kaalhus, O; Mikalsen, SO | 1 |
| Guillory, RJ; Li, J | 1 |
| Garat, C; Matthay, MA; Oliver, BL; Pytela, R | 1 |
| Rosen, BP; Xu, C | 1 |
| Scott, AG; Tait, A; Turner, CM | 1 |
| Hirsch, S; Miskimins, R; Miskimins, WK | 1 |
| Adcock, IM; Barnes, PJ; Bergmann, M; Kuitert, LM; Newton, R | 1 |
| Abreu, LC; Freymüller, E; Lázari, MF; Picarelli, ZP; Porto, CS | 1 |
| Maloney, JA; Pei, Z; Williamson, JR; Yang, L | 1 |
| Aggarwal, BB; Dhawan, S; Singh, S | 1 |
| Han, YP; Kohanski, RA | 1 |
| Baker, RD; Baker, SS; Gupta, A; Holycross, M; Rao, RK | 1 |
| Durry, S; Günzel, D; Schlue, WR | 1 |
| Bandyopadhyay, U; Guse, AH; Kaiser, T; Mayr, GW; Rudolf, MT; Schultz, C | 1 |
| Cao, J; Chen, M; Wang, Q | 1 |
| Pelham, RJ; Wang, Yl | 2 |
| Duarte, J; Ocete, MA; Pérez-Vizcaino, F; Tamargo, J; Zarzuelo, A | 1 |
| Durden, DL; Erdreich-Epstein, A; Liu, M; Liu, Y | 1 |
| Bechara, EJ; Meinicke, AR; Vercesi, AE | 1 |
| Castilho, RF; Kowaltowski, AJ | 1 |
| Born, JL; Curry, MS; Edwards, BS; Gale, JM; Graf, LH; Robinson, MK; Salazar, F; Southon, EA | 1 |
| Blais, C; Doussiere, J; Poinas, A; Vignais, PV | 1 |
| Butov, SN; Krutetskaia, NI; Krutetskaia, ZI; Lebedev, OE; Petrova, TV | 1 |
| Bauersachs, J; Busse, R; Fisslthaler, B; Fleming, I | 1 |
| Fan, G; Kren, BT; Rodrigues, CM; Steer, CJ; Wong, PY | 1 |
| Ferreri, NR; Mahboubi, K; Young, W | 2 |
| Fisher, SK; Heacock, AM; Linseman, DA; McEwen, EL; Sorensen, SD | 1 |
| Cavallaro, U; Maier, JA; Marchisio, PC; Soria, MR; Wu, Z | 1 |
| Carlini, CR; Francischetti, IM; Guimarães, JA | 1 |
| Hughes, AD; Lymn, JS; Wijetunge, S | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| May, JM; Mendiratta, S; Qu, ZC | 1 |
| Balakirev, MY; Zimmer, G | 1 |
| Brown, CL; Carpenter, G; Dempsey, PJ; Rudolph-Owen, LA; Vecchi, M | 1 |
| Hawker, J; Huang, Q; Meng, FY; Wu, HM; Yuan, Y | 1 |
| Audus, KL; Rose, JM | 1 |
| Khvotchev, M; Südhof, TC | 1 |
| Bernardi, P; Fontaine, E; Ichas, F | 1 |
| Pasco, DS; Siu, CS; Xu, C | 1 |
| Chavrier, P; Guillemot, JC; Massol, P; Montcourrier, P | 1 |
| Ivey, CL; Parker, JC; Tucker, A | 1 |
| Abd-Elfattah, AS; Mahgoub, MA; Taher, MM | 1 |
| Brigelius-Flohé, R; Friedrichs, B; Müller, C | 1 |
| Amatore, C; Arbault, S; Best-Belpomme, M; Edeas, M; Legrand-Poels, S; Lindenbaum, A; Piette, J; Sojic, N; Vuillaume, M | 1 |
| Chang, AT; Crook, RB; Lehman, NL | 1 |
| Amatore, C; Arbault, S; Bizzini, B; Bruce, D; Lachgar, A; Sarasin, A; Sojic, N; Vuillaume, M; Zagury, D | 1 |
| Fedinec, A; Leffler, CW; Parfenova, H | 1 |
| Brendle, JJ; Sackett, DL; Werbovetz, KA | 1 |
| Gómez-Niño, A; Gonzalez, C; Obeso, A | 1 |
| Ponnappan, U; Trebilcock, GU; Zheng, MZ | 1 |
| Chancy, C; Ganapathy, V; Huang, W; Smith, SB | 1 |
| Namiki, H; Suzuki, K | 1 |
| Francischetti, IM; Guimarães, JA; Jandrot-Perrus, M; Lagrue, AH | 1 |
| Kwiatkowska, K; Sobota, A | 1 |
| Bedoya, FJ; Camacho, MJ; Carballo, M; Conde, J; Conde, M; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Sobrino, F | 1 |
| Brenner, C; Decaudin, D; Jacotot, E; Kroemer, G; Larochette, N; Marzo, I; Reed, J; Susin, SA; Xie, Z; Zamzami, N | 1 |
| Dibas, A; Prasanna, G; Yorio, T | 1 |
| Bartlett, SE; Hendry, IA; Heydon, K; Reynolds, AJ | 1 |
| Barnes, DM; Miller, DS; Sykes, DB | 1 |
| Bernardi, P; Colonna, R; Di Lisa, F; Petronilli, V; Scorrano, L | 1 |
| Italiano, JE; Roberts, TM; Stewart, M | 1 |
| Hassid, A; Huang, S; Yao, J | 1 |
| Hamadeh, HK; Lee, E; Menzel, DB; Vargas, M | 1 |
| Chernyak, BV | 2 |
| Aggarwal, BB; Estey, EH; Estrov, Z; Harris, D; Kantarjian, HM; Manna, SK; Talpaz, M; Van, Q | 1 |
| Cornejo MacIel, F; Mendez, C; Paz, C; Podesta, EJ | 1 |
| Jenkins, SM; Johnson, GV | 2 |
| Fisher, SK; Linseman, DA; Sorensen, SD | 1 |
| Bedoya, FJ; Carballo, M; Conde, M; Hmadcha, A; Márquez, G; Martin-Nieto, J; Monteseirín, J; Pintado, E; Sobrino, F | 1 |
| Ehler, E; Fontana, A; Frei, K; Gloor, SM; Wachtel, M; Winterhalter, K | 1 |
| Aggarwal, BB; Chintala, SK; Gokslan, Z; Kyritsis, AP; Mohan, PM; Mohanam, S; Rao, JS; Sawaya, R; Steck, P; Uhm, JH; Yung, WK | 1 |
| Camello, PJ; Lajas, AI; Pariente, JA; Pozo, MJ; Salido, GM | 1 |
| Bouzidi, F; Doussiere, J; Gaillard, J; Poinas, A; Vignais, PV | 1 |
| Bonkovsky, HL; Hong Lu, T; Lambrecht, RW; Shan, Y | 1 |
| Eggler, J; Gabel, CA; Laliberte, RE | 1 |
| Dème, D; Dupuy, C; Noël-Hudson, MS; Ohayon, R; Valent, A; Virion, A | 1 |
| Jan, MS; Lin, MT; Lin, YS; Wing, LY | 1 |
| Böl, GF; Brigelius-Flohé, R; Tewes, F | 1 |
| Inoue, T; Kaibori, M; Kamiyama, Y; Oda, M; Okumura, T; Sakitani, K | 1 |
| Albumi, C; De Michelis, MI; Olivari, C; Pugliarello, MC | 1 |
| Bogumil, R; Hellstern, S; Mutzel, R; Namgaladze, D; Schaarschmidt, D; Schmachtel, T; Ullrich, V | 1 |
| Akiyama, K; Fukai, F; Goto, S; Goto, T; Kamiya, S; Katayama, T; Ohwaki, T | 1 |
| Crause, P; Gloe, T; Keller, M; Pohl, U; Sohn, HY | 1 |
| Bennett, TA; Edwards, BS; Rogelj, S; Sklar, LA | 1 |
| Bloom, P; Gu, R; Wang, W; Wei, Y | 1 |
| Searl, TJ; Silinsky, EM | 1 |
| Cabral, CM; Choudhury, P; Liu, Y; Sifers, RN | 1 |
| Castilho, RF; Kowaltowski, AJ; Teixeira, BM; Vercesi, AE | 1 |
| Biaglow, JE; Chrestensen, C; Donahue, J; Held, K; Mieyal, J; Tuttle, S | 1 |
| Agapito, MT; Gonzalez, C; Obeso, A; Sanz-Alfayate, G | 1 |
| Baker, E; Hallmann, R; Morgan, EH; Savigni, DL | 1 |
| Ayene, IS; Biaglow, JE; Donahue, J; Koch, CJ; Stamato, TD; Tuttle, SW | 1 |
| Berman, SB; Hastings, TG; Watkins, SC | 1 |
| Abraham, WC; Coussens, CM; Ireland, DR; Williams, JM | 1 |
| Davis, J; Schiebinger, R; Yingst, DR | 1 |
| Kawahara, T; Kawai, T; Kishi, K; Miyoshi, M; Rokutan, K; Teshima, S | 1 |
| Maher, PA | 1 |
| Bastiaens, PI; Reynolds, AR; Verveer, PJ; Wouters, FS | 1 |
| Berglund, MM; Kane, JK; Li, MD; Lundell, IA; Parker, MS; Parker, SL | 1 |
| Laden, BP; Porter, TD | 1 |
| Donoghue, N; Hogg, PJ; Jiang, XM; Yam, PT | 1 |
| Caro, MC; Jiménez, E; Marsigliante, S; Montiel, M | 1 |
| Conde, M; Porras, T; Rosado, JA; Sage, SO | 1 |
| Block, ER; Su, Y | 1 |
| Goldhaber, JI; Korge, P; Weiss, JN | 1 |
| Lavielle, S; Sagan, S | 1 |
| Kemp, PJ; O'Kelly, I; Peers, C | 1 |
| Brotzu, G; Cappai, A; Fattore, L; Onali, P; Petruzzo, P; Picciau, S; Serra, G; Spiga, S | 1 |
| Bouzidi, F; Doussière, J; Vignais, PV | 1 |
| Kovács, P; Pintér, M | 1 |
| Chen, M; Geng, JG | 2 |
| Brüne, B; Kietzmann, T; Sandau, KB; Zhou, J | 1 |
| Bianchetti, R; Malerba, M | 1 |
| Barg, I; Buschermöhle, T; Dulkys, Y; Elsner, J; Kapp, A; Kluthe, C; Knöss, S; Proudfoot, AE | 1 |
| Falck, JR; Gu, RM; Krishna, UM; Wang, WH; Wei, Y | 1 |
| Liu, J; Shen, X; Yue, J | 1 |
| Danon, A; Trebitsh, T | 1 |
| Horikomi, K; Karasawa, J; Nukada, T; Okuyama, S; Sagi, N; Sora, I; Takahashi, S; Yamamoto, H; Yamamoto, T | 1 |
| Bernardi, P; Kristian, T; Siesjö, BK | 1 |
| Small, PL; Snyder, DS | 1 |
| Alexander, JS; Kevil, CG; Okayama, N | 1 |
| Grill, E; Meinhard, M | 1 |
| Bonkovsky, HL; Gildemeister, OS; Lambrecht, RW; Pepe, JA | 1 |
| Li, X; May, JM; Qu, ZC | 1 |
| Sawada, Y; Sheetz, MP | 1 |
| Haier, J; Nicolson, GL | 1 |
| Fernandez, M; Luis Albasanz, J; Martín, M | 1 |
| Alberto Olivares-Reyes, J; Catt, KJ; Shah, BH; Yesilkaya, A | 1 |
| Halvorsen, SW; Kaur, N; Wohlhueter, AL | 1 |
| Grill, E; Meinhard, M; Rodriguez, PL | 1 |
| Bogumil, R; Ullrich, V | 1 |
| Mann, BJ; Teixeira, JE | 1 |
| Bartlett, SE; Hendry, IA; Reynolds, AJ; Weible, M | 1 |
| Berglund, MM; Kane, JK; Parker, MS; Parker, SL | 1 |
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| Bild, AH; Jove, R; Turkson, J | 1 |
| Horie, S; Mori, A; Murayama, T; Nomura, Y; Ohsawa, K; Okuma, Y; Saito, T | 1 |
| Sensi, SL; Ton-That, D; Weiss, JH | 1 |
| Balasubramaniam, A; Berglund, MM; Buschauer, A; Kane, JK; Lundell, I; Parker, MS; Parker, SL; Yalcin, A | 1 |
| Clarke, SJ; Halestrap, AP; McStay, GP | 1 |
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| Hahn, JH; Han, K; Jee, B; Jung, KC; Kim, E; Lee, H; Lee, HJ; Park, SH | 1 |
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| González-Segura, L; Mújica-Jiménez, C; Muñoz-Clares, RA | 1 |
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| Alvarez, R; González-Serratos, H; Irles, C; Jiménez, A; Ortega, A; Pérez, F; Tirado, A; Vázquez, P | 1 |
| Arnér, ES; Cheng, Q; Jörnvall, H; Rengby, O; Vahter, M | 1 |
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| Andreu, D; Bray, F; de la Torre, BG; Díez-Dacal, B; García de Lacoba, M; García-Domínguez, CA; Oeste, CL; Pérez-Inestrosa, E; Pérez-Sala, D; Rojas, JM; Ruiz-Sánchez, AJ | 1 |
| De Vos, WH; Shahidi-Noghabi, S; Smagghe, G; Van Damme, EJ | 1 |
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| Feito, MJ; Gonçalves, G; Linares, J; Marques, PA; Matesanz, MC; Portolés, MT; Vallet-Regí, M; Vila, M | 1 |
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5 review(s) available for oxophenylarsine and arsenic
| Article | Year |
|---|---|
Phenylarsine oxide and the mechanism of insulin-stimulated sugar transport.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport, Active; Carbohydrate Metabolism; Depression, Chemical; Humans; Insulin; Insulin Antagonists; Liver; Monosaccharide Transport Proteins; Muscles; Protein Binding; Rats; Receptor, Insulin; Receptors, Cell Surface | 1990 |
Effects of arsenicals on the secretory process in chromaffin cells.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Arsenicals; Cattle; Cells, Cultured; Diamide; Dithiothreitol; Exocytosis; Norepinephrine; PC12 Cells; Pheochromocytoma | 1994 |
Protein tyrosine phosphorylation modulates microvessel permeability in frog mesentery.
Topics: Animals; Anura; Arsenicals; Capillary Permeability; Colforsin; Cyclic AMP; Dimercaprol; Endothelium, Vascular; Enzyme Inhibitors; Mesentery; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Pyrrolidinones; Rolipram; Serum Albumin, Bovine; Signal Transduction | 1996 |
[The research method for investigating the role of the mitochondrial permeability transition pore in cell death].
Topics: Apoptosis; Arsenicals; Calcium; Cyclosporine; Cytochromes c; Diazoxide; Humans; Ion Channels; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Necrosis; Ouabain | 2004 |
Cyclophilin-D inhibition in neuroprotection: dawn of a new era of mitochondrial medicine.
Topics: Animals; Arsenicals; Brain Injuries; Calcium; Cyclophilins; Cyclosporine; Enzyme Inhibitors; Humans; Ischemia; Mitochondria; Neuroprotective Agents; Peptidyl-Prolyl Isomerase F | 2013 |
524 other study(ies) available for oxophenylarsine and arsenic
| Article | Year |
|---|---|
Phenylarsine oxide augments tyrosine phosphorylation in hematopoietic cells.
Topics: Aged; Animals; Arsenicals; Blood Platelets; Busulfan; Cell Line; Dithiothreitol; Gene Rearrangement; Granulocytes; Humans; Hydroxyurea; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Phosphates; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Tyrosine | 1992 |
Identification of the adipocyte acid phosphatase as a PAO-sensitive tyrosyl phosphatase.
Topics: 3T3 Cells; Acid Phosphatase; Adipose Tissue; Amino Acid Sequence; Animals; Arsenicals; Base Sequence; Cattle; Cloning, Molecular; Cytosol; Erythrocytes; Escherichia coli; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Liver; Mice; Molecular Sequence Data; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Substrate Specificity; Sulfhydryl Compounds | 1992 |
Evidence for two distinct phosphorylation pathways activated by high affinity immunoglobulin E receptors.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Arsenicals; Calcium; Cell Line; Cytosol; Immunoglobulin E; Kinetics; Mast Cells; Phosphatidylinositols; Phosphorylation; Receptors, Fc; Receptors, IgE; Serotonin; Type C Phospholipases | 1992 |
Interaction between the p21ras GTPase activating protein and the insulin receptor.
Topics: 3T3 Cells; Animals; Arsenicals; GTPase-Activating Proteins; Humans; Immunoblotting; Macromolecular Substances; Mice; Molecular Weight; Peptide Mapping; Phosphopeptides; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Receptor, Insulin; Transfection; Trypsin | 1992 |
Tyrosine kinase regulation of a molluscan circadian clock.
Topics: Animals; Arsenicals; Biological Clocks; Circadian Rhythm; Ethers, Cyclic; Eye; Genistein; Isoflavones; Okadaic Acid; Phosphates; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Snails; Tyrosine | 1992 |
Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.
Topics: Antigens, Differentiation; Arsenicals; Calcium; Cell Line; Cross-Linking Reagents; Humans; Immunoglobulin G; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Receptors, Fc; Receptors, IgG; Type C Phospholipases; Tyrosine | 1992 |
Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization.
Topics: Animals; Antimycin A; Arsenicals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cations, Divalent; Cyclosporins; Ethylmaleimide; Hydrogen-Ion Concentration; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; Permeability; Phosphates; Rats; Ruthenium Red; Succinates; Succinic Acid | 1992 |
Correlation of follicle-stimulating hormone (FSH)-receptor complex internalization with the sustained phase of FSH-induced calcium uptake by cultured rat Sertoli cells.
Topics: Animals; Arsenicals; Calcium; Calcium Radioisotopes; Cells, Cultured; Chloroquine; Follicle Stimulating Hormone; Follicle Stimulating Hormone, beta Subunit; Kinetics; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Sertoli Cells | 1992 |
Inactivation of ribonuclease inhibitor by thiol-disulfide exchange.
Topics: Animals; Arsenicals; Cattle; Chromatography, Affinity; Cross-Linking Reagents; Disulfides; Dithionitrobenzoic Acid; Intracellular Signaling Peptides and Proteins; Kinetics; Protein Conformation; Proteins; Recombinant Proteins; Ribonuclease, Pancreatic; Saccharomyces cerevisiae; Swine | 1992 |
Desensitization of bradykinin-induced activation of peripheral nociceptors.
Topics: Animals; Animals, Newborn; Arsenicals; Bradykinin; Concanavalin A; In Vitro Techniques; Membrane Potentials; Nerve Fibers; Nociceptors; Rats; Spinal Cord | 1992 |
Stage-specific tyrosine phosphorylation of actin in Dictyostelium discoideum cells.
Topics: Actins; Animals; Antibodies; Arsenicals; Cell Differentiation; Cytoskeleton; Dictyostelium; Phosphorylation; Tyrosine; Up-Regulation | 1992 |
Existence of two pathways for the endocytosis of epidermal growth factor by rat liver: phenylarsine oxide-sensitive and -insensitive pathways.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Dose-Response Relationship, Drug; Endocytosis; Epidermal Growth Factor; ErbB Receptors; In Vitro Techniques; Liver; Perfusion; Rats; Rotenone | 1992 |
Trafficking of glucose transporters in 3T3-L1 cells. Inhibition of trafficking by phenylarsine oxide implicates a slow dissociation of transporters from trafficking proteins.
Topics: 3T3 Cells; Affinity Labels; Animals; Arsenicals; Azides; Biological Transport; Cell Membrane; Disaccharides; Endocytosis; Exocytosis; Fibroblasts; Glucose; Glycosides; Kinetics; Mice; Monosaccharide Transport Proteins; Photochemistry; Propylamines | 1992 |
Iodophenylarsine oxide and arsenical affinity chromatography: new probes for dithiol proteins. Application to tubulins and to components of the insulin receptor-glucose transporter signal transduction pathway.
Topics: 3T3 Cells; Adipose Tissue; Affinity Labels; Amino Acid Sequence; Animals; Arsenicals; Chromatography, Affinity; Disulfides; Insulin; Iodine Radioisotopes; Kinetics; Mice; Molecular Sequence Data; Monosaccharide Transport Proteins; Probability; Protein Conformation; Receptor, Insulin; Sequence Homology, Nucleic Acid; Signal Transduction; Tubulin | 1992 |
Recycling of transferrin receptors and heparan sulfate proteoglycans in a rat parathyroid cell line.
Topics: Affinity Labels; Animals; Arsenicals; Biological Transport; Calcium; Cations, Divalent; Cells, Cultured; Egtazic Acid; Endocytosis; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Iodine Radioisotopes; Kinetics; Nocodazole; Parotid Gland; Proteoglycans; Rats; Receptors, Transferrin; Trypsin | 1992 |
Inhibition of ubiquitin-protein ligase (E3) by mono- and bifunctional phenylarsenoxides. Evidence for essential vicinal thiols and a proximal nucleophile.
Topics: Animals; Arsenicals; Binding Sites; Kinetics; Ligases; Rabbits; Reticulocytes; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Compounds; Ubiquitin-Protein Ligases | 1992 |
Phenylarsine oxide stimulates a cytosolic tyrosine kinase activity and glucose transport in mouse fibroblasts.
Topics: 3T3 Cells; Animals; Arsenicals; Cell Line; Cell-Free System; Cytosol; Deoxyglucose; Glucose; Insulin; Kinetics; Methionine; Mice; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Receptor, Insulin | 1991 |
Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide.
Topics: Animals; Arsenicals; Cell Line; Kinetics; Lymphocyte Activation; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; T-Lymphocytes; Tyrosine | 1990 |
Multiple pathways for ligand internalization in rat hepatocytes. I: Effects of anoxia, phenylarsine oxide and monensin.
Topics: Adenosine Triphosphate; alpha-Fetoproteins; Animals; Arsenicals; Asialoglycoproteins; Cell Hypoxia; Endocytosis; Epidermal Growth Factor; Fetuins; Insulin; Liver; Male; Monensin; Rats; Rats, Inbred Strains | 1991 |
Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase.
Topics: Animals; Arginine; Arsenicals; Binding Sites; Binding, Competitive; Cattle; Cyclohexanones; Cysteine; Epoxy Compounds; Glutathione; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Weight; Phenylglyoxal; Protein Tyrosine Phosphatases | 1992 |
Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations.
Topics: Arsenicals; Calcium; Cations, Divalent; Egtazic Acid; Fluoresceins; Hydrogen-Ion Concentration; Kinetics; Manganese; Mitochondria; Nigericin; Oxygen Consumption; Permeability; Sodium | 1992 |
Effects of insulin and phospholipase C in control and denervated rat skeletal muscle.
Topics: Animals; Arsenicals; Biological Transport, Active; Calcium; Dantrolene; Deoxyglucose; Diaphragm; Diglycerides; Insulin; Kinetics; Male; Muscle Denervation; Muscles; Phospholipases A; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Type C Phospholipases | 1991 |
Phosphotyrosyl turnover in insulin signaling. Characterization of two membrane-bound pp15 protein tyrosine phosphatases from 3T3-L1 adipocytes.
Topics: Adipose Tissue; Arsenicals; Cells, Cultured; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Membrane Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Substrate Specificity | 1991 |
Regulation of arachidonic acid metabolism by phenylarsine oxide.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Arsenicals; Bradykinin; Calcimycin; Cell Line; Epoprostenol; Kinetics; Liver; Lymphoma; Mice; Platelet Activating Factor; Rats | 1991 |
Different regulation of vascular tone by angiotensin II and endothelin-1 in rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arsenicals; Calcium; Culture Media; Endothelins; Humans; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Swine; Temperature | 1991 |
[The role of the ADP/ATP-antiporter in the inhibition of nonspecific permeability of the inner mitochondrial membrane by cyclosporin A].
Topics: Arsenicals; Calcium; Cyclosporins; Ethylmaleimide; Intracellular Membranes; Mersalyl; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Permeability | 1991 |
Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arsenicals; Cells, Cultured; Choline; Egtazic Acid; Hydrolysis; Kinetics; Male; Muscle, Smooth, Vascular; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondria.
Topics: Animals; Arsenicals; Butylated Hydroxytoluene; Calcium; Cyclosporine; Intracellular Membranes; Kinetics; Membrane Potentials; Mitochondria, Liver; Permeability; Rats | 1991 |
Effects of phenylarsine oxide on insulin-stimulated system A amino acid uptake in skeletal muscle.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Arsenicals; Insulin; Insulin-Like Growth Factor I; Kinetics; Male; Muscles; Rats; Sulfhydryl Compounds; Vanadates | 1991 |
Insulin-induced p21ras activation does not require protein kinase C, but a protein sensitive to phenylarsine oxide.
Topics: 3T3 Cells; Animals; Arsenicals; Down-Regulation; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Insulin; Mice; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Receptor, Insulin; Receptors, Antigen, T-Cell; Signal Transduction; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate | 1991 |
Phenylarsine oxide causes an insulin-dependent, GLUT4-specific degradation in rat adipocytes.
Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Arsenicals; Cells, Cultured; Chloroquine; Insulin; Kinetics; Male; Methylglucosides; Models, Biological; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Receptor, Insulin | 1991 |
Highly insulin-responsive isolated rat heart muscle cells yielded by a modified isolation method.
Topics: 3-O-Methylglucose; Animals; Arsenicals; Biological Transport; Cell Separation; Cytochalasin B; Deoxyglucose; Female; Glucose; Insulin; Kinetics; Methylglucosides; Myocardium; Rats; Rats, Inbred Strains | 1991 |
Agonist-induced endocytosis and signal generation in adrenal glomerulosa cells. A potential mechanism for receptor-operated calcium entry.
Topics: Angiotensin II; Animals; Arsenicals; Biological Transport; Calcium; Cattle; Cells, Cultured; Dithiothreitol; Endocytosis; Mercaptoethanol; Potassium; Signal Transduction; Zona Glomerulosa | 1991 |
Receptor-mediated endocytosis of A14-125I-insulin by the nonfiltering perfused rat kidney.
Topics: Animals; Arsenicals; Chromatography, High Pressure Liquid; Endocytosis; Hydrogen-Ion Concentration; Insulin; Inulin; Iodine Radioisotopes; Kidney; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Perfusion; Rats; Rats, Inbred Strains; Receptor, Insulin | 1991 |
Phenylarsine oxide inhibits insulin-dependent glucose transport activity in rat soleus muscles.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Biological Transport, Active; Deoxyglucose; Glucose; In Vitro Techniques; Insulin; Kinetics; Magnetic Resonance Spectroscopy; Muscles; Phosphorylation; Rats; Receptor, Insulin | 1991 |
Characterization of a transferrin-independent uptake system for iron in HeLa cells.
Topics: Arsenicals; Binding, Competitive; Biological Transport; Cadmium; Egtazic Acid; HeLa Cells; Humans; Hydrogen-Ion Concentration; Iron; Kinetics; Temperature; Transferrin; Trypsin | 1990 |
An essential role for vicinal dithiol groups in the catalytic activity of the human placental Na(+)-H+ exchanger.
Topics: Amiloride; Arsenicals; Binding Sites; Biological Transport; Carrier Proteins; Cimetidine; Humans; Hydrogen; Microvilli; Placenta; Sodium-Hydrogen Exchangers | 1990 |
Mechanisms of mercurial and arsenical inhibition of tyrosine absorption in intestine of the winter flounder Pseudopleuronectus americanus.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Arsenic Poisoning; Arsenicals; Flatfishes; Flounder; Intestinal Absorption; Intestinal Mucosa; Intracellular Fluid; Mercuric Chloride; Microvilli; Phenylmercury Compounds; Potassium; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase; Tyrosine | 1990 |
Insulin receptor tyrosine kinase-catalyzed phosphorylation of 422(aP2) protein. Substrate activation by long-chain fatty acid.
Topics: Adipose Tissue; Animals; Arsenicals; Carrier Proteins; Cell Line; Chromatography, Ion Exchange; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Insulin; Kinetics; Mice; Models, Molecular; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Oleic Acid; Oleic Acids; Phosphorylation; Protein Conformation; Protein-Tyrosine Kinases; Receptor, Insulin | 1990 |
Effects of phenylarsine oxide on stimulation of glucose transport in rat skeletal muscle.
Topics: 3-O-Methylglucose; Animals; Arsenicals; Biological Transport, Active; Dose-Response Relationship, Drug; Electric Stimulation; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Insulin; Isometric Contraction; Kinetics; Male; Methylglucosides; Methylglycosides; Muscles; Rats; Rats, Inbred Strains; Type C Phospholipases; Vanadates | 1990 |
Evidence for the involvement of vicinal sulfhydryl groups in the insulin stimulation of intracellular glucose metabolism in Zajdela hepatoma cells.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Glucose; Insulin; Insulin Antagonists; L-Lactate Dehydrogenase; Lipids; Liver Glycogen; Liver Neoplasms, Experimental; Protein-Tyrosine Kinases; Receptor, Insulin; Sulfhydryl Compounds; Sulfhydryl Reagents; Tumor Cells, Cultured | 1990 |
Reactive sulfhydryl groups in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.
Topics: Arsenic; Arsenicals; Arsenites; Cadmium; Dimercaprol; Dithionitrobenzoic Acid; Kinetics; Phosphoenolpyruvate Carboxykinase (GTP); Saccharomyces cerevisiae; Spectrometry, Fluorescence; Sulfhydryl Compounds; Zinc | 1990 |
Uptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport; Cell Fractionation; Deoxyglucose; Insulin; Intracellular Fluid; Kinetics; Stimulation, Chemical; Time Factors; Tritium | 1990 |
The role of insulin receptor sulphydryl groups in insulin binding and cellular response in rat adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Binding, Competitive; Cell Membrane; Dithiothreitol; Glucose; Insulin; Kinetics; Monosaccharide Transport Proteins; Rats; Receptor, Insulin; Sulfhydryl Compounds | 1990 |
Internalization-sequestration and degradation of cholecystokinin (CCK) in tumoral rat pancreatic AR 4-2 J cells.
Topics: Animals; Arsenicals; Binding, Competitive; Cell Membrane; Chloroquine; Cholecystokinin; Cytochalasin D; Dinitrophenols; Endocytosis; Gastrins; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Pancreas; Pancreatic Neoplasms; Rats; Sincalide; Succinimides; Temperature; Tumor Cells, Cultured | 1990 |
Effect of ADP/ATP antiporter conformational state on the suppression of the nonspecific permeability of the inner mitochondrial membrane by cyclosporine A.
Topics: Animals; Arsenicals; Calcium; Cyclosporins; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Permeability; Protein Conformation; Rats; Sulfhydryl Reagents | 1990 |
Analysis of angiotensin II binding to human platelets: differences in young and old subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Arsenicals; Binding, Competitive; Blood Platelets; Chromatography, High Pressure Liquid; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Species Specificity; Time Factors | 1990 |
Production of 1,2-diacylglycerol in PC12 cells by nerve growth factor and basic fibroblast growth factor.
Topics: Acids; Adenosine; Adrenal Gland Neoplasms; Animals; Arsenicals; Calcium; Carbachol; Culture Media; Deoxyadenosines; Diglycerides; Extracellular Space; Fibroblast Growth Factors; Glycerides; Inositol Phosphates; Nerve Growth Factors; Pheochromocytoma; Potassium; Thionucleosides; Tumor Cells, Cultured | 1990 |
Transcellular transport of angiotensin II through a cultured arterial endothelial monolayer.
Topics: Adenosine Triphosphate; Ammonium Chloride; Angiotensin II; Animals; Arsenicals; Binding, Competitive; Biological Transport; Chromatography, Gel; Endothelium, Vascular; In Vitro Techniques; Iodine Radioisotopes; Monensin; Temperature | 1990 |
Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: evidence for fusion of internal receptor pools with the cell surface.
Topics: alpha-Macroglobulins; Animals; Arsenicals; Calcium; Cell Membrane; Exocytosis; Intracellular Membranes; Lectins, C-Type; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Magnesium; Mannose; Mannose Receptor; Mannose-Binding Lectins; Membrane Fusion; Methylamines; Pulmonary Alveoli; Rabbits; Receptors, Cell Surface; Receptors, Concanavalin A; Receptors, Immunologic; Receptors, Transferrin; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Reagents; Trypsin | 1985 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Cell Line; Deoxyglucose; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Trypsin; Tyrosine; Vanadates | 1988 |
Phenylarsine oxide inhibition of endocytosis: effects on asialofetuin internalization.
Topics: Adenosine Triphosphate; alpha-Fetoproteins; Animals; Arsenicals; Asialoglycoproteins; Cells, Cultured; Endocytosis; Fetuins; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred Strains | 1989 |
Involvement of thiol groups in the function of the dipeptide/proton cotransport system in rabbit renal brush-border membrane vesicles.
Topics: Animals; Arsenicals; Biological Transport; Carrier Proteins; Dimercaprol; Dipeptides; Dithionitrobenzoic Acid; Kidney Cortex; Kinetics; Methylphenazonium Methosulfate; Microvilli; Naphthoquinones; Oxidation-Reduction; Protons; Rabbits; Structure-Activity Relationship; Sulfhydryl Compounds | 1989 |
Absorptive-mediated endocytosis of a dynorphin-like analgesic peptide, E-2078 into the blood-brain barrier.
Topics: Animals; Arsenicals; Blood-Brain Barrier; Brain; Capillaries; Cattle; Chromatography, High Pressure Liquid; Dynorphins; Endocytosis; In Vitro Techniques; Male; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains | 1989 |
Phenylarsine oxide stimulates hexose transport in 3T3-L1 adipocytes by a mechanism other than an increase in surface transporters.
Topics: Adipose Tissue; Animals; Arsenicals; Cell Membrane; Cells, Cultured; Insulin; Kinetics; Mice; Monosaccharide Transport Proteins; Phosphorylation; Receptors, Transferrin | 1989 |
Common pathway for the induction of hexose transport by insulin and stress.
Topics: Amiloride; Animals; Arsenicals; Biological Transport, Active; Cells, Cultured; Deoxyglucose; Hexoses; Hydrogen Peroxide; Insulin; Monosaccharide Transport Proteins; Rats; Stress, Physiological | 1989 |
Insulin processing and signal transduction in rat adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Glucose; In Vitro Techniques; Insulin; Male; Monensin; Rats; Rats, Inbred Strains; Receptor, Insulin; Signal Transduction | 1989 |
Effects of three proposed inhibitors of adipocyte glucose transport on the reconstituted transporter.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport; Cell Membrane; Dimethyl Sulfoxide; Dipeptides; Dose-Response Relationship, Drug; Erythrocyte Membrane; Glucose; Glucose-6-Phosphate; Glucosephosphates; Humans; Insulin; Liposomes; Membrane Lipids; Monosaccharide Transport Proteins; Rats; Trypsin | 1989 |
A further comparison of insulin- and phorbol ester-stimulated glucose transport in adipocytes.
Topics: Adenosine Triphosphate; Adipose Tissue; Alkaloids; Animals; Arsenicals; Biological Transport, Active; Cell Fractionation; Cell Survival; Deoxyglucose; Glucose; In Vitro Techniques; Insulin; Kinetics; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Effect of phenylarsine oxide on fluid phase endocytosis: further evidence for activation of the glucose transporter.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport; Cell Line; Cell Membrane; Endocytosis; Exocytosis; Glucose; Insulin; Membrane Fluidity; Microscopy, Electron; Monosaccharide Transport Proteins; Rats; Time Factors | 1989 |
Reconstitution of glucose transport activity in liposomes to test proposed modulators of the transporter.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Erythrocyte Membrane; Glucose; Glucose-6-Phosphate; Glucosephosphates; Humans; In Vitro Techniques; Liposomes; Microsomes; Stereoisomerism | 1989 |
Effect of phenylarsine oxide on protein synthesis in 3T3-L1 adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport; Cell Line; Cycloheximide; Glucose; In Vitro Techniques; Insulin Antagonists; Mice; Protein Biosynthesis | 1989 |
Correlation of receptor sequestration with sustained diacylglycerol accumulation in angiotensin II-stimulated cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arsenicals; Calcium; Cells, Cultured; Chloroquine; Diglycerides; Dithiothreitol; Endocytosis; Glycerides; Hydrolysis; Muscle, Smooth, Vascular; Phosphatidylinositols; Rats; Receptors, Angiotensin; Temperature | 1987 |
Potential involvement of vicinal sulfhydryls in stimulus-induced rabbit platelet activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arsenicals; Blood Platelets; Calcimycin; Cyclic AMP; Molecular Weight; Platelet Activating Factor; Rabbits; Sulfhydryl Reagents; Thrombin | 1987 |
Evidence for the existence of at least two different binding sites for 5HT-reuptake inhibitors within the 5HT-reuptake system from human platelets.
Topics: Arsenicals; Binding Sites; Blood Platelets; Carrier Proteins; Cysteine; Dithiothreitol; Ethylmaleimide; Humans; Imipramine; Neurotransmitter Uptake Inhibitors; Quinolines; Receptors, Drug; Receptors, Neurotransmitter; Serotonin | 1988 |
Internalization and cycling of nerve growth factor in PC12 cells: interconversion of type II (fast) and type I (slow) nerve growth factor receptors.
Topics: Animals; Arsenicals; Chloroquine; Digitonin; Endocytosis; Monensin; Nerve Growth Factors; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Tumor Cells, Cultured | 1988 |
Binding and internalization of atrial natriuretic factor by high-affinity receptors in A10 smooth muscle cells.
Topics: Animals; Arsenicals; Atrial Natriuretic Factor; Biological Transport; Cell Line; Cyclic GMP; Guanylate Cyclase; Membranes; Molecular Weight; Muscle, Smooth, Vascular; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1986 |
Phenylarsine oxide inhibits agonist-induced changes in photolabeling but not agonist-induced desensitization of the beta-adrenergic receptor.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Affinity Labels; Arsenicals; Dithiothreitol; Humans; Lymphocytes; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta | 1986 |
Effects of phenylarsine oxide on agonist-induced hepatic vasoconstriction and glycogenolysis.
Topics: Adrenergic alpha-Agonists; Arsenic; Arsenicals; Liver; Liver Glycogen; Perfusion; Vasoconstriction | 1988 |
Inactivation of chicken liver mevalonate 5-diphosphate decarboxylase by sulfhydryl-directed reagents: evidence of a functional dithiol.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Carboxy-Lyases; Chickens; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrogen-Ion Concentration; Kinetics; Liver; Methyl Methanesulfonate; Mevalonic Acid; Sulfhydryl Reagents; Toluene | 1989 |
ATP-driven transhydrogenase provides an example of delocalized chemiosmotic coupling in reconstituted vesicles and in submitochondrial particles.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arsenicals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Energy Transfer; NAD; NADH, NADPH Oxidoreductases; NADP Transhydrogenases; Oxidation-Reduction; Submitochondrial Particles | 1987 |
Phenylarsine oxide and denervation effects on hormone-stimulated glucose transport.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Biological Transport, Active; Deoxy Sugars; Deoxyglucose; Insulin; Insulin-Like Growth Factor I; Kinetics; Male; Muscle Denervation; Muscles; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Somatomedin; Reference Values | 1988 |
A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide.
Topics: Adenosine Triphosphate; Arsenicals; Astrocytoma; Catecholamines; Cell Line; Dithiothreitol; Endocytosis; Epidermal Growth Factor; Humans; Iodocyanopindolol; Isoproterenol; Pindolol; Propanolamines; Receptors, Adrenergic, beta | 1985 |
Down-regulation of parathyroid hormone (PTH) receptors in cultured bone cells is associated with agonist-specific intracellular processing of PTH-receptor complexes.
Topics: Animals; Arsenicals; Bone and Bones; Cell Membrane; Cells, Cultured; Chick Embryo; Chloroquine; Cyclic AMP; Drug Synergism; Monensin; Parathyroid Hormone; Peptide Fragments; Receptors, Cell Surface; Receptors, Parathyroid Hormone | 1986 |
Desensitization of the beta-adrenergic receptor-coupled adenylate cyclase in cultured mammalian cells. Receptor sequestration versus receptor function.
Topics: Adenylyl Cyclases; Animals; Arsenicals; Cell Line; Concanavalin A; Dose-Response Relationship, Drug; Humans; Isoproterenol; Propanolamines; Rats; Receptors, Adrenergic, beta; Time Factors | 1986 |
Phorbol ester-induced upregulation of angiotensin II receptors in neuronal cultures is potentiated by a calcium ionophore.
Topics: Angiotensin II; Animals; Arsenicals; Brain; Calcimycin; Calcium Radioisotopes; Cells, Cultured; Drug Synergism; Neurons; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetradecanoylphorbol Acetate | 1988 |
Evidence for a role of a vicinal dithiol in the transport of gamma-butyrobetaine in Agrobacterium sp.
Topics: Arsenicals; Betaine; Biological Transport, Active; Carnitine; Ethylmaleimide; Rhizobium; Sulfhydryl Reagents | 1988 |
Direct interaction of phenylarsine oxide with hexose transporters in isolated rat adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Binding, Competitive; Biological Transport; Cytochalasin B; Glucose; Mice; Monosaccharide Transport Proteins; Rats; Stereoisomerism; Time Factors | 1988 |
Renal processing of vasopressin.
Topics: Animals; Arginine Vasopressin; Arsenicals; Hydrolysis; In Vitro Techniques; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Rats | 1988 |
Transmodulation of the epidermal-growth-factor receptor in permeabilized 3T3 cells.
Topics: Animals; Arsenicals; Cell Line; Cell Membrane Permeability; Chlorpromazine; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Mice, Inbred BALB C; Neomycin; Nucleotides; Platelet-Derived Growth Factor | 1988 |
The action of phenylarsine oxide on the stereospecific uptake of D-glucose in basal and insulin-stimulated rat adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Biological Transport, Active; Cell Membrane; Deoxyglucose; Dithiothreitol; Glucose; Insulin; Kinetics; Male; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Receptor, Insulin; Stereoisomerism | 1988 |
Involvement of hormone processing in insulin-activated glucose transport by isolated cardiac myocytes.
Topics: 3-O-Methylglucose; Adenosine Triphosphate; Animals; Arsenicals; Biological Transport, Active; Cadaverine; Cell Separation; Chloroquine; Glucose; Heart; In Vitro Techniques; Insulin; Isoproterenol; Kinetics; Male; Methylglucosides; Myocardium; Rats; Rats, Inbred Strains | 1988 |
Effect of phenylarsine oxide on insulin-dependent protein phosphorylation and glucose transport in 3T3-L1 adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Cells, Cultured; Glucose; Insulin; Kinetics; Mice; Phosphoproteins; Phosphorylation; Receptor, Insulin | 1987 |
Regulation of immune-aggregate-stimulated hepatic glycogenolysis and vasoconstriction by vicinal dithiols.
Topics: Adenine Nucleotides; Animals; Antigen-Antibody Complex; Arsenicals; Calcium; Glucagon; Glucose; Immunoglobulin Fragments; Isoproterenol; Liver; Liver Glycogen; Male; Phenylephrine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Vasoconstriction | 1988 |
Sensitivity of mitochondrial Mg++ flux to reagents which affect K+ flux.
Topics: Animals; Arsenicals; Barium; Biological Transport, Active; Dicyclohexylcarbodiimide; In Vitro Techniques; Magnesium; Mitochondria, Liver; Potassium; Rats | 1988 |
Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes.
Topics: Adipose Tissue; Animals; Arsenicals; Cells, Cultured; Enzyme Activation; Insulin; Kinetics; Mice; Molecular Weight; Phosphorus Radioisotopes; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Receptor, Insulin | 1987 |
Stimulation of K+ flux into mitochondria by phenylarsine oxide.
Topics: Animals; Arsenicals; Biological Transport, Active; Dicyclohexylcarbodiimide; Kinetics; Mercaptoethanol; Mersalyl; Mitochondria, Liver; Oxygen Consumption; Potassium; Rats | 1986 |
Radiosensitization by diamide analogs and arsenicals.
Topics: Animals; Arsenicals; Azo Compounds; Cell Survival; Cricetinae; Diamide; In Vitro Techniques; Radiation-Sensitizing Agents | 1986 |
Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.
Topics: 3-O-Methylglucose; Adenosine Triphosphate; Adipose Tissue; Animals; Arsenicals; Biological Transport, Active; Cytochalasin B; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Hexokinase; Insulin; Kinetics; Methylglucosides; Mice; Receptor, Insulin; Structure-Activity Relationship | 1985 |
The effect of inhibitors of insulin processing on generation of insulin intermediate products from human fibroblast as detected by high performance liquid chromatography (HPLC).
Topics: Arsenicals; Bacitracin; Cadaverine; Cell Line; Chloroquine; Chromatography, High Pressure Liquid; Ethylmaleimide; Fibroblasts; Humans; Insulin; Male | 1985 |
Internalization of the neonatal brain insulin receptor.
Topics: Amino Acids; Animals; Animals, Newborn; Arsenicals; Brain Chemistry; Chloroquine; Deoxyglucose; In Vitro Techniques; Leucine; Rabbits; Receptor, Insulin | 1985 |
Inhibition of coupling factor B activity by cadmium ion, arsenite-2,3-dimercaptopropanol, and phenylarsine oxide, and preferential reactivation by dithiols.
Topics: Adenosine Triphosphatases; Animals; Arsenic; Arsenicals; Cadmium; Cattle; Cysteine; Dimercaprol; Glutathione; Kinetics; Mercaptoethanol; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Sulfhydryl Compounds | 1981 |
The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis.
Topics: Arsenicals; Cell Line; Cell Membrane; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Kinetics; Ligands; Male; Receptors, Cell Surface; Skin | 1982 |
Chemical modification of the lactose carrier of Escherichia coli by plumbagin, phenylarsinoxide or diethylpyrocarbonate affects the binding of galactoside.
Topics: Arsenicals; Binding Sites; Biological Transport; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Escherichia coli Proteins; Formates; Galactosides; Glycosides; Membrane Transport Proteins; Monosaccharide Transport Proteins; Naphthoquinones; Protein Binding; Symporters | 1983 |
Arsenic-sulfur amino acid interactions in the chick.
Topics: Amino Acids, Sulfur; Animals; Arsenates; Arsenic Poisoning; Arsenicals; Body Weight; Cysteine; Drug Interactions; Food Additives; Glutathione; Male; Methionine; Mortality; Roxarsone; Stereoisomerism; Swine | 1984 |
Physical mechanism for regulation of proton solute symport in Escherichia coli.
Topics: Arsenicals; Biological Transport, Active; Dithiothreitol; Escherichia coli; Escherichia coli Proteins; Kinetics; Lactose; Membrane Transport Proteins; Monosaccharide Transport Proteins; Naphthoquinones; Oxidation-Reduction; Proline; Sulfhydryl Reagents; Symporters | 1982 |
Inhibition of D(--)-beta-hydroxybutyrate dehydrogenase by modifiers of disulfides, thiols, and vicinal dithiols.
Topics: Acetoacetates; Animals; Arsenicals; Azo Compounds; Cattle; Diamide; Disulfides; Hydroxybutyrate Dehydrogenase; Kinetics; Mitochondria, Heart; Submitochondrial Particles; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfides; Sulfites | 1981 |
Activation of potassium-dependent H+ efflux from mitochondria by cadmium and phenylarsine oxide.
Topics: Animals; Arsenicals; Biological Transport, Active; Cadmium; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Mitochondria, Liver; Potassium; Rats; Sodium | 1981 |
Influence of glucose on the toxicity of oxophenylarsine in MDCK cells.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Arsenic Poisoning; Arsenicals; Cell Line; Cell Survival; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Kidney; Pyruvate Dehydrogenase Complex | 1995 |
Binding of phenylarsenoxide to Arg-tRNA protein transferase is independent of vicinal thiols.
Topics: Acyltransferases; Alanine; Aminoacyltransferases; Arsenicals; Base Sequence; Cysteine; DNA Primers; Iodine Radioisotopes; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Saccharomyces cerevisiae; Serine; Sulfhydryl Compounds | 1995 |
A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation.
Topics: Animals; Arsenicals; Calcium; Clone Cells; Concanavalin A; Fatty Acids, Nonesterified; Genistein; Ionomycin; Isoflavones; Kinetics; Lymphocyte Activation; Mice; Molecular Weight; Oleic Acid; Oleic Acids; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Strong increase in the tyrosine phosphorylation of actin upon inhibition of oxidative phosphorylation: correlation with reversible rearrangements in the actin skeleton of Dictyostelium cells.
Topics: Actins; Adenosine Triphosphate; Animals; Arsenicals; Cytoskeleton; Dictyostelium; Dinitrophenols; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Isoflavones; Microscopy, Fluorescence; Oxidative Phosphorylation; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine | 1994 |
Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Animals; Arsenicals; Blotting, Western; Calcium; Carrier Proteins; Cyclosporine; Diamide; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Ion Channels; Mitochondria, Liver; Molecular Sequence Data; Peptidylprolyl Isomerase; Peroxides; Rats; tert-Butylhydroperoxide | 1994 |
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Arsenicals; Cell Line, Transformed; Chloroquine; Colchicine; Endocytosis; Epithelium; Hypertonic Solutions; Immune Sera; Immunohistochemistry; Kinetics; Leupeptins; Microscopy, Fluorescence; Molecular Sequence Data; Monensin; Peptides; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Time Factors; Transfection | 1994 |
Angiotensin AT2 receptor mediated inhibition of particulate guanylate cyclase: a link with protein tyrosine phosphatase stimulation?
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Aorta; Arsenicals; Atrial Natriuretic Factor; Cell Membrane; Cells, Cultured; Cyclic GMP; GTP-Binding Proteins; Guanylate Cyclase; Muscle, Smooth, Vascular; Oligopeptides; PC12 Cells; Protein Tyrosine Phosphatases; Rats; Receptors, Angiotensin; Vanadates | 1994 |
Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils.
Topics: Apoptosis; Arsenicals; Eosinophils; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Isoflavones; Neutrophils; Phosphoprotein Phosphatases; Phosphotyrosine; Signal Transduction; Tyrosine | 1994 |
Complete and reversible inhibition of NADPH oxidase in human neutrophils by phenylarsine oxide at a step distal to membrane translocation of the enzyme subunits.
Topics: Adenosine Triphosphate; Arsenicals; Cell Compartmentation; Cell Degranulation; Cell Membrane; Dimercaprol; Humans; In Vitro Techniques; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phagocytosis; Phosphotyrosine; Protein Tyrosine Phosphatases; Superoxides; Tyrosine | 1995 |
Rapid desensitization of B-cell receptor by a dithiol-reactive protein tyrosine phosphatase inhibitor: uncoupling of membrane IgM from syk inhibits signals leading to Ca2+ mobilization.
Topics: Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Arsenicals; B-Lymphocytes; Burkitt Lymphoma; Calcium; Disulfides; Down-Regulation; Drug Interactions; Enzyme Precursors; Humans; Hydrogen Peroxide; Immunoglobulin M; Intracellular Signaling Peptides and Proteins; Neoplasm Proteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Syk Kinase; Tumor Cells, Cultured | 1995 |
Reversal of oxophenylarsine-induced inhibition of glucose uptake in MDCK cells.
Topics: Adenosine Triphosphate; Animals; Antidotes; Arsenic Poisoning; Arsenicals; Biological Transport; Cell Line; Dimercaprol; Dithiothreitol; Dogs; Enzyme Inhibitors; Glucose; L-Lactate Dehydrogenase; Mercaptoethanol; Succimer; Sulfonamides; Unithiol | 1995 |
Phenylarsine oxide inhibits tyrosine phosphorylation of phospholipase C gamma 2 in human platelets and phospholipase C gamma 1 in NIH-3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Antigens, CD; Arsenicals; Blood Platelets; Collagen; Enzyme Inhibitors; Humans; Inositol Phosphates; Isoenzymes; Mice; Phospholipase C gamma; Phosphorylation; Platelet Activation; Platelet-Derived Growth Factor; Receptors, IgG; Type C Phospholipases; Tyrosine | 1995 |
Activated adhesion of CTL to MHC class I but not to fibronectin is inhibited by cis unsaturated fatty acids and phenylarsine oxide.
Topics: Animals; Antibodies, Monoclonal; Arsenicals; Cell Adhesion; Fatty Acids, Unsaturated; Fibronectins; H-2 Antigens; Interleukin-2; Lymphocyte Activation; Mice; Phosphatidylinositols; Phosphorylation; Protein Processing, Post-Translational; Receptors, Antigen, T-Cell; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic | 1995 |
Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.
Topics: Amino Acid Sequence; Animals; Arsenicals; Binding Sites; CHO Cells; Cricetinae; GTPase-Activating Proteins; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Receptor, IGF Type 1; SH2 Domain-Containing Protein Tyrosine Phosphatases; Type C Phospholipases; Tyrosine | 1995 |
Tertiary structure-selective characterization of protein dithiol groups by phenylarsine oxide modification and mass spectrometric peptide mapping.
Topics: Amino Acid Sequence; Arsenicals; Chromatography, High Pressure Liquid; Endopeptidases; Escherichia coli; Indicators and Reagents; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Protein Biosynthesis; Protein Structure, Tertiary; Proteins; Recombinant Proteins; Spectrometry, Mass, Fast Atom Bombardment; Thioredoxins; Trypsin | 1995 |
Effect of phenylarsine oxide on hepatic alpha 1-adrenoreceptor responsiveness. Dissociation between ionotropic and metabolic responses.
Topics: Animals; Arsenicals; Calcium; Food; Gluconeogenesis; Hemodynamics; Ion Transport; Liver; Male; Protons; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sodium; Starvation | 1995 |
Insulin regulation of protein phosphorylation in H4 hepatoma cells. Examination of rapid effects using two-dimensional electrophoresis.
Topics: Animals; Arsenicals; Electrophoresis, Gel, Two-Dimensional; Insulin; Kinetics; Liver Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Phosphoproteins; Phosphotyrosine; Protease Inhibitors; Rats; Tumor Cells, Cultured; Tyrosine | 1993 |
Complex effects of phenylarsine oxide in T cells. Induction of tyrosine phosphorylation and calcium mobilization independent of CD45 expression.
Topics: Arsenicals; Calcium; CD3 Complex; Dimercaprol; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Weight; Phosphoproteins; Phosphotyrosine; T-Lymphocytes; Tyrosine | 1993 |
Evidence for participation of vicinal dithiols in the activation sequence of the respiratory burst of human neutrophils.
Topics: Arachidonic Acid; Arsenicals; Blood Proteins; Calcium; Cell-Free System; Cytosol; Dimercaprol; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Respiratory Burst; Signal Transduction; Sulfhydryl Compounds; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.
Topics: Adenosine Triphosphate; Arsenicals; Base Sequence; Ceramides; Diamide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Ethers, Cyclic; Humans; I-kappa B Proteins; In Vitro Techniques; Interleukin-1; Marine Toxins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligodeoxyribonucleotides; Oxazoles; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vanadates | 1995 |
Influence of 2,3-dimercaptopropanol and other sulfur compounds on oxophenylarsine-mediated inhibition of glucose uptake in MDCK cells.
Topics: Animals; Arsenicals; Biological Transport; Cell Line; Dimercaprol; Dithiothreitol; Dogs; Glucose; Insulin; Kidney; Mercaptoethanol; Sulfur | 1995 |
Modulation of phorbol ester-induced respiratory burst by vanadate, genistein, and phenylarsine oxide in mouse macrophages.
Topics: Animals; Arsenicals; Genistein; Isoflavones; Macrophages, Peritoneal; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
A synthetic peptide corresponding to residues 645-653 in the carboxyl terminal cytoplasmic domain of the rat testicular follicle stimulating hormone receptor modulates G protein coupled-receptor signaling in rat testis membranes and in intact cultured rat
Topics: Amino Acid Sequence; Animals; Arsenicals; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Estradiol; Follicle Stimulating Hormone; GTP-Binding Proteins; Male; Molecular Sequence Data; Peptides; Rats; Rats, Sprague-Dawley; Receptors, FSH; Sertoli Cells; Signal Transduction; Testis | 1995 |
Okadaic acid, vanadate, and phenylarsine oxide stimulate 2-deoxyglucose transport in insulin-resistant human skeletal muscle.
Topics: Adult; Animals; Arsenicals; Biological Transport; Deoxyglucose; Ethers, Cyclic; Humans; Insulin Resistance; Male; Muscle, Skeletal; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Vanadates | 1995 |
Receptor-mediated internalization of angiotensin II in bovine adrenal medullary chromaffin cells in primary culture.
Topics: Adrenal Medulla; Angiotensin II; Animals; Arsenicals; Cattle; Cells, Cultured; Endocytosis; Iodine Radioisotopes; Kinetics; Monensin; Receptors, Angiotensin; Saralasin | 1994 |
Vanadate-induced oscillatory inward Cl- currents in Xenopus laevis oocytes.
Topics: Angiotensin II; Animals; Arsenicals; Atropine; Calcium; Chloride Channels; Collagenases; Electrophysiology; Female; GTP-Binding Proteins; In Vitro Techniques; Lithium Chloride; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Vanadates; Virulence Factors, Bordetella; Xenopus laevis | 1994 |
Potentiation by insulin and insulin-like growth factor-1 of glibenclamide-sensitive K+ currents in follicle-enclosed Xenopus oocytes.
Topics: Animals; Antihypertensive Agents; Arsenicals; Benzopyrans; Cromakalim; Drug Synergism; Female; Glyburide; Insulin; Insulin-Like Growth Factor I; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Pyrroles; Virulence Factors, Bordetella; Xenopus laevis | 1994 |
Calcium dependent cellular uptake of a c-myc antisense oligonucleotide.
Topics: Animals; Arsenicals; Base Sequence; Biological Transport; Calcium; Cell Line; Chloroquine; Deoxyglucose; Genes, myc; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Macrophages; Molecular Sequence Data; Monensin; Oligonucleotides, Antisense; Proto-Oncogene Mas; Trypsin; Tumor Cells, Cultured | 1994 |
Platelet shape change and Ca2+ mobilization induced by collagen, but not thrombin or ADP, are inhibited by phenylarsine oxide.
Topics: Adenosine Diphosphate; Arsenicals; Blood Platelets; Calcium; Cells, Cultured; Collagen; Dimercaprol; Electrophoresis, Polyacrylamide Gel; Humans; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Thrombin | 1994 |
Direct observation of endocytosis of gastrin releasing peptide and its receptor.
Topics: Amino Acid Sequence; Animals; Arsenicals; Endocytosis; Gastrin-Releasing Peptide; Gastrins; Humans; Mice; Molecular Sequence Data; Osmolar Concentration; Peptides; Protein Binding; Receptors, Bombesin; Sucrose; Transferrin | 1995 |
Activation of phospholipase D in human platelets by collagen and thrombin and its relationship to platelet aggregation.
Topics: Adenosine Triphosphate; Arsenicals; Blood Platelets; Collagen; Enzyme Activation; Ethers, Cyclic; Humans; Okadaic Acid; Phospholipase D; Platelet Aggregation; Platelet Aggregation Inhibitors; Sphingosine; Thrombin | 1994 |
Induction of hyperphosphorylation and activation of the p56lck protein tyrosine kinase by phenylarsine oxide, a phosphotyrosine phosphatase inhibitor.
Topics: Animals; Arsenicals; Cell Line, Transformed; Cytoskeleton; Enzyme Activation; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Peptide Mapping; Phosphorus Radioisotopes; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured | 1994 |
Phenylarsine oxide inhibits insulin-stimulated protein phosphatase 1 activity and GLUT-4 translocation.
Topics: Adipocytes; Animals; Arsenicals; Biological Transport; Cell Membrane; Enzyme Activation; Glucose Transporter Type 4; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley | 1994 |
Phenylarsine oxide stimulates pyridine nucleotide-linked Ca2+ release from rat liver mitochondria.
Topics: 3-Iodobenzylguanidine; Animals; Arsenicals; Calcium; Cyclosporine; In Vitro Techniques; Iodobenzenes; Membrane Potentials; Mitochondria, Liver; Nucleotides; Pyridines; Rats | 1994 |
Anti-CD2-induced tyrosine phosphorylation of T cell polypeptides is independent of the PMA-induced modification of p56lck.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Arsenicals; CD2 Antigens; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitosis; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Immunologic; Serine; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1993 |
Phenylarsine oxide and phorbol myristate acetate inhibit the CD3-induced rise of cytosolic Ca2+ in Jurkat cells by refilling internal Ca2+ stores.
Topics: Arsenicals; Biological Transport; Calcium; CD3 Complex; Cell Line; Cytosol; Ethers, Cyclic; Humans; Ionomycin; Okadaic Acid; Phosphatidylserines; Phosphorylation; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1994 |
Protein tyrosine phosphatase inhibitors block myeloid signal transduction through the Fc gamma RI receptor.
Topics: Amino Acid Sequence; Arsenicals; Bone Marrow; Cells, Cultured; Humans; Microscopy, Electron; Molecular Sequence Data; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Receptors, IgG; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Potent activation of phospholipase D by phenylarsine oxide in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Arsenicals; Benzoquinones; Calcium; Cell Line; Enzyme Activation; Genistein; Isoflavones; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Oleic Acid; Oleic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phospholipase D; Phosphoproteins; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tumor Cells, Cultured | 1994 |
Angiotensin II-dependent proximal tubule sodium transport requires receptor-mediated endocytosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arsenicals; Biological Transport; Cell Membrane; Cells, Cultured; Endocytosis; Imidazoles; Kidney Tubules, Proximal; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium; Sodium-Hydrogen Exchangers | 1994 |
Stable expression of the cloned rat brain neurotensin receptor into fibroblasts: binding properties, photoaffinity labeling, transduction mechanisms, and internalization.
Topics: Animals; Arsenicals; Cell Line; Cloning, Molecular; Colforsin; Deoxyribonuclease I; DNA; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Iodine Radioisotopes; Mutation; Neurotensin; Promoter Regions, Genetic; Protein Binding; Pyrazoles; Quinolines; Rats; Receptors, Neurotensin; RNA, Messenger; Signal Transduction; Transfection | 1994 |
Phenylarsine oxide and hydrogen peroxide stimulate glucose transport via different pathways in isolated cardiac myocytes.
Topics: 3-O-Methylglucose; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arsenicals; Biological Transport; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Ethers, Cyclic; Ethylmaleimide; Glucose; Heart; Hydrogen Peroxide; Insulin; Methylglucosides; Myocardium; Okadaic Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vanadates | 1993 |
Phenylarsine oxide (PAO) blocks antigen receptor-induced calcium response and tyrosine phosphorylation of a distinct group of proteins.
Topics: Arsenicals; B-Lymphocytes; Calcium; CD3 Complex; Cell Survival; Cells, Cultured; DNA; DNA Replication; Flow Cytometry; Humans; Immunoglobulin M; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1993 |
Attenuation of insulin actions in primary rat hepatocyte cultures by phenylarsine oxide.
Topics: Amino Acids; Animals; Arsenicals; Cells, Cultured; Drug Interactions; Fructosediphosphates; Glucokinase; Glucose; Glycogen; Glycolysis; Insulin; Liver; Male; Phosphofructokinase-1; Phosphorylation; Pyruvate Kinase; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction | 1993 |
Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Animals; Arsenicals; Atractyloside; Carnitine; Cell Death; Cell Hypoxia; Cells, Cultured; Cyclosporine; Intracellular Membranes; Kinetics; Liver; Male; Membrane Potentials; Mitochondria, Liver; para-Aminobenzoates; Permeability; Potassium Cyanide; Rats; Rats, Sprague-Dawley; Rotenone; Time Factors | 1993 |
Sulfhydryl reactive phenylarsine oxide inhibits signal transduction in NK and LAK cells: effect on zeta-chain phosphorylation and phosphatidylinositol level.
Topics: Arsenicals; Humans; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Membrane Proteins; Phosphatidylinositols; Phosphorylation; Receptors, Antigen, T-Cell; Signal Transduction; Sulfhydryl Compounds; Tyrosine | 1993 |
Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells.
Topics: Arsenicals; Cell Adhesion Molecules; Cells, Cultured; Endocytosis; Endothelium, Vascular; Gene Expression Regulation; Humans; Hypertonic Solutions; Protease Inhibitors; Putrescine; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Transcriptional Activation; Tumor Necrosis Factor-alpha | 1993 |
Tyrosine phosphorylation of a 100-kDa protein is correlated with cytotoxic T-lymphocyte function. Evidence from cis unsaturated fatty acid and phenylarsineoxide inhibition.
Topics: Animals; Arsenicals; Cell Line; Cyclic AMP; Densitometry; Fatty Acids, Unsaturated; Immunoblotting; Kinetics; Mice; Phosphorylation; Protein Tyrosine Phosphatases; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured; Tyrosine | 1993 |
Arsenical-resistant trypanosomes lack an unusual adenosine transporter.
Topics: Adenine; Adenosine; Animals; Antiprotozoal Agents; Arsenicals; Biological Transport; Carrier Proteins; Drug Resistance; Inosine; Kinetics; Melarsoprol; Trypanosoma brucei brucei | 1993 |
Regulation of contraction-stimulated system A amino acid uptake in skeletal muscle: role of vicinal sulfhydryls.
Topics: Amino Acids; Animals; Arsenicals; beta-Alanine; Dimercaprol; Electric Stimulation; Insulin; Kinetics; Male; Muscle Contraction; Muscles; Rats; Rats, Wistar | 1993 |
Influence of inorganic and organic arsenicals on intestinal transfer of nutrients.
Topics: Animals; Arsenic; Arsenic Trioxide; Arsenicals; Body Water; Dose-Response Relationship, Drug; Glucose; Intestinal Mucosa; Jejunum; Leucine; Male; Oxides; Rats; Rats, Sprague-Dawley; Sodium | 1993 |
Identification of Schizosaccharomyces pombe gene psk1+, encoding a novel putative serine/threonine protein kinase, whose mutation conferred resistance to phenylarsine oxide.
Topics: Amino Acid Sequence; Arsenicals; Base Sequence; Chromosome Mapping; Cloning, Molecular; DNA, Fungal; Drug Resistance, Microbial; Enzyme Inhibitors; Fungal Proteins; Gene Expression; Genes, Fungal; Molecular Sequence Data; Mutagenesis, Insertional; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; RNA, Fungal; RNA, Messenger; Schizosaccharomyces; Schizosaccharomyces pombe Proteins | 1995 |
Angiotensin II tachyphylaxis in the guinea pig ileum and its prevention: a pharmacological and biochemical study.
Topics: Alkaloids; Angiotensin II; Animals; Arsenicals; Calcium; Cells, Cultured; Cold Temperature; Female; Guinea Pigs; Ileum; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Protein Kinase C; Sodium; Staurosporine; Tachyphylaxis | 1995 |
Involvement of vicinal dithiols in differential regulation of fMLP and phorbol ester-activated phospholipase D in stimulated human neutrophils.
Topics: Arsenicals; Calcium; Cells, Cultured; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Effects of the protein tyrosine phosphatase inhibitor phenylarsine oxide on excision-activated calcium channels in Lymnaea neurons.
Topics: Animals; Arsenicals; Calcium Channels; Ion Channel Gating; Lymnaea; Neurons; Patch-Clamp Techniques; Protein Tyrosine Phosphatases | 1995 |
Differential role of protein tyrosine phosphorylation/dephosphorylation in affinity regulation of beta 1 and beta 3 integrin in human fibroblasts.
Topics: Antibodies, Monoclonal; Antigens, CD; Arsenicals; Cell Adhesion; Enzyme Inhibitors; Fibroblasts; Humans; Integrin beta1; Integrin beta3; Integrins; Phosphorylation; Platelet Membrane Glycoproteins; Tyrosine; Vanadates | 1995 |
Effect of phenylarsine oxide on the fission yeast Schizosaccharomyces pombe cell cycle.
Topics: Arsenicals; Cell Cycle; Cell Division; Enzyme Inhibitors; Mutation; Protein Tyrosine Phosphatases; Schizosaccharomyces | 1995 |
Inhibitory effect of pyruvate on release of glutathione and swelling of rat heart mitochondria.
Topics: Animals; Arsenicals; Biological Transport; Calcium; Depression, Chemical; Glutathione; Hypoxia; In Vitro Techniques; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Phosphates; Pyruvates; Pyruvic Acid; Rats | 1995 |
Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate.
Topics: Alendronate; Amino Acid Sequence; Animals; Arsenicals; Bone Marrow Cells; Bone Resorption; Cloning, Molecular; Coculture Techniques; Diphosphonates; Enzyme Inhibitors; Gene Expression; Isoenzymes; Kinetics; Mice; Molecular Sequence Data; Osteoclasts; Protein Tyrosine Phosphatases; Rats; Recombinant Fusion Proteins; Skull; Vanadates | 1996 |
Differential whole-cell extract preparation and electrophoretic mobility shift assay to evaluate the effect of tyrosine phosphatases on DNA binding activity of transcription factors.
Topics: Animals; Arsenicals; DNA-Binding Proteins; Electrophoresis, Agar Gel; Enzyme Inhibitors; HeLa Cells; Humans; Mice; Phosphoproteins; Protein Tyrosine Phosphatases; Transcription Factors; Tumor Cells, Cultured | 1996 |
The role of arsenic-thiol interactions in metalloregulation of the ars operon.
Topics: Amino Acid Sequence; Antimony; Arsenicals; Arsenites; Bacterial Proteins; Base Sequence; Cysteine; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Helix-Turn-Helix Motifs; Kinetics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Operon; Protein Structure, Secondary; R Factors; Repressor Proteins; Sequence Homology, Amino Acid; Serine; Trans-Activators | 1996 |
Interdependence of calcium signaling and protein tyrosine phosphorylation in human endothelial cells.
Topics: Amino Acid Sequence; Arsenicals; Bradykinin; Calcium; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Inhibitors; Humans; Inositol Phosphates; Isoenzymes; Molecular Sequence Data; Phospholipase C gamma; Phosphorylation; Polyethylene Glycols; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Type C Phospholipases; Tyrosine | 1996 |
Mechanism of ubiquitin conjugating enzyme E2-230K: catalysis involving a thiol relay?
Topics: Animals; Arsenicals; Catalysis; Dithiothreitol; Enzyme Inhibitors; Ligases; Models, Biological; Models, Chemical; Rabbits; Reticulocytes; Sulfhydryl Compounds; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitins | 1996 |
Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Arsenicals; Bridged Bicyclo Compounds; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Glutathione; Hydroxybutyrates; Intracellular Membranes; Ion Channel Gating; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Permeability; Rats; Rotenone; Sulfhydryl Compounds | 1996 |
Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion.
Topics: 1-Phosphatidylinositol 4-Kinase; Adrenal Glands; Animals; Arsenicals; Cattle; Cells, Cultured; Chromaffin Granules; Exocytosis; Phosphatidylinositols; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Quercetin | 1996 |
Receptor up-regulation, internalization, and interconverting receptor states. Critical components of a quantitative description of N-formyl peptide-receptor dynamics in the neutrophil.
Topics: Amino Acid Sequence; Arsenicals; Fluoresceins; Humans; In Vitro Techniques; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Neutrophils; Oligopeptides; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Temperature; Up-Regulation; Virulence Factors, Bordetella | 1996 |
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2.
Topics: Arsenicals; Bradykinin; Calcium; Calcium-Transporting ATPases; Cell Line; Endocytosis; Extracellular Space; Fluorescent Antibody Technique; Humans; Interleukin-8; Intestinal Mucosa; Kidney; Lysosomes; Microscopy, Confocal; Protein Kinase C; Receptor, PAR-2; Receptors, Cell Surface; Terpenes; Thapsigargin; Trypsin; Type C Phospholipases | 1996 |
Phenylarsine oxide and vanadate: apparent paradox of inhibition of protein phosphotyrosine phosphatases in rat adipocytes.
Topics: 3-O-Methylglucose; Adipocytes; Animals; Arsenicals; Cells, Cultured; Enzyme Inhibitors; Epididymis; Ethers, Cyclic; Glycerol; Glycolysis; Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Methylglucosides; Okadaic Acid; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Vanadates | 1996 |
The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites.
Topics: Animals; Arsenicals; Calcimycin; Calcium; Cross-Linking Reagents; Glutathione; Intracellular Membranes; Ion Channel Gating; Mitochondria, Liver; NAD; NADP; Nucleotides; Oligomycins; Oxidants; Oxidation-Reduction; Oxidative Stress; Permeability; Pyridines; Rats; Sulfhydryl Compounds; Valinomycin | 1996 |
Regulated binding of PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of beta-catenin.
Topics: Actins; Animals; Antibodies, Monoclonal; Arsenicals; Benzoquinones; beta Catenin; Cadherins; Cell Adhesion; Cell Fractionation; Chick Embryo; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Genistein; Isoflavones; Lactams, Macrocyclic; Ligands; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Retina; Rifabutin; Trans-Activators; Transferases (Other Substituted Phosphate Groups) | 1996 |
The phosphotyrosine phosphatase inhibitor-phenylarsine oxide restores defective phosphoinositide hydrolysis response in anergic C3H-gld/gld lymphocytes.
Topics: Animals; Arsenicals; Cell Survival; Clonal Anergy; Concanavalin A; Dose-Response Relationship, Immunologic; Hydrolysis; Inositol 1,4,5-Trisphosphate; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Phosphatidylinositols; Protein Tyrosine Phosphatases | 1996 |
Bradykinin-stimulated protein tyrosine phosphorylation promotes endothelial nitric oxide synthase translocation to the cytoskeleton.
Topics: Animals; Antibodies; Aorta; Arsenicals; Benzoquinones; Bradykinin; Carrier Proteins; Cattle; Cells, Cultured; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; Isoenzymes; Kinetics; Lactams, Macrocyclic; Nitric Oxide Synthase; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones | 1996 |
Uptake mechanism of fractioned [(3)H]heparin in isolated rat kupffer cells: involvement of scavenger receptors.
Topics: 2,4-Dinitrophenol; Animals; Arsenicals; Binding, Competitive; Biological Transport; Cytochalasin B; Endocytosis; Enzyme Inhibitors; Heparin; Kinetics; Kupffer Cells; Ligands; Liver; Male; Membrane Proteins; Phagocytosis; Protein Binding; Rats; Rats, Wistar; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Rotenone; Scavenger Receptors, Class B; Temperature; Uncoupling Agents | 1996 |
Phenylarsine oxide (PAO)-mediated activation of phospholipase D in rat basophilic leukemia (RBL-2H3) cells: possible involvement of calcium and protein kinase C.
Topics: Animals; Antigens; Arsenicals; Calcium; Dimercaprol; Dithiothreitol; Enzyme Activation; Leukemia, Mast-Cell; Phospholipase D; Protein Kinase C; Rats; Tumor Cells, Cultured | 1996 |
Redox regulation of signal transduction in smooth muscle cells: protein kinase C inhibition by thiol agents.
Topics: Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Ethylmaleimide; Hydrogen Peroxide; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oxidation-Reduction; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinase C; Signal Transduction; Vanadates | 1996 |
Activation-independent nuclear translocation of mitogen activated protein kinase ERK1 mediated by thiol-modifying chemicals.
Topics: Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Enzyme Activation; Ethylmaleimide; Fluorescent Antibody Technique, Indirect; Microtubules; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Rats; S Phase; Sulfhydryl Reagents; Tubulin; Tyrosine; Vanadates | 1996 |
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons.
Topics: Animals; Animals, Newborn; Arsenicals; Cell Membrane; Cells, Cultured; Endocytosis; Guinea Pigs; Male; Myenteric Plexus; Nerve Fibers; Neurites; Neurons; Platelet Aggregation Inhibitors; Potassium; Receptors, Neurokinin-1; Substance P; Sucrose | 1996 |
Kinetic analysis of the mitochondrial permeability transition.
Topics: Animals; Arsenicals; Calcium; Carbohydrate Metabolism; Enzyme Inhibitors; Intracellular Membranes; Kinetics; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Phosphates; Platelet Aggregation Inhibitors; Rats | 1996 |
Effect of modulators of tyrosine kinase activity on agonist-induced contraction in the rat pulmonary vascular smooth muscle.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Arsenicals; Calcium; Dantrolene; Enzyme Inhibitors; Escin; Genistein; In Vitro Techniques; Intracellular Fluid; Isoflavones; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Protein-Tyrosine Kinases; Pulmonary Artery; Rats; Rats, Wistar; Thapsigargin; Vasoconstrictor Agents | 1996 |
Focal adhesion and stress fiber formation is regulated by tyrosine phosphatase activity.
Topics: 3T3 Cells; Actins; Animals; Arsenicals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Mice; Paxillin; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Substrate Specificity | 1996 |
Apoptosis in barley aleurone during germination and its inhibition by abscisic acid.
Topics: Abscisic Acid; Apoptosis; Arsenicals; DNA Fragmentation; Enzyme Inhibitors; Germination; Gibberellins; Hordeum; Okadaic Acid; Phosphorylation; Protoplasts; Seeds; Signal Transduction | 1996 |
Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase.
Topics: Adenosine Diphosphate; Animals; Arsenicals; Atractyloside; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Diamide; Intracellular Membranes; Membrane Potentials; Mitochondria; Mitochondrial ADP, ATP Translocases; Nucleotides; Oxidative Stress; Permeability; Peroxides; Rats; Reactive Oxygen Species; Sulfhydryl Reagents; tert-Butylhydroperoxide | 1997 |
Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages.
Topics: 3T3 Cells; Animals; Arsenicals; Cell Adhesion; Cell Movement; Chickens; Cytoskeleton; Enzyme Inhibitors; Extracellular Matrix; Fibronectins; Lasers; Mice; Microspheres; Protein Tyrosine Phosphatases; Pseudopodia; Receptors, Fibronectin | 1997 |
Regulation of the thyroid NADPH-dependent H2O2 generator by Ca2+: studies with phenylarsine oxide in thyroid plasma membrane.
Topics: Animals; Arsenicals; Calcium; Cell Membrane; Ferricyanides; Hydrogen Peroxide; NADH, NADPH Oxidoreductases; Sulfhydryl Compounds; Swine; Thyroid Gland | 1997 |
Mitochondrial membrane protein thiol reactivity with N-ethylmaleimide or mersalyl is modified by Ca2+: correlation with mitochondrial permeability transition.
Topics: Animals; Arsenicals; Binding Sites; Calcium; Ethylmaleimide; In Vitro Techniques; Intracellular Membranes; Membrane Proteins; Mersalyl; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Peroxides; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfhydryl Reagents; tert-Butylhydroperoxide | 1997 |
Sensitization to DNA damage by okadaic acid or bromodeoxyuridine involves unequal effects on melanoma cell adhesion and differentiation.
Topics: Animals; Antimetabolites, Antineoplastic; Arsenicals; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cycloheximide; DNA Damage; DNA Fragmentation; Enzyme Inhibitors; Melanoma; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Pigmentation; Protein Synthesis Inhibitors; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Ultraviolet Rays | 1997 |
Insulin-induced tyrosine phosphorylation of a M(r) 70,000 protein revealed by association with the Src homology 2 (SH2) and SH3 domains of p120GAP and Grb2.
Topics: 3T3 Cells; Animals; Arsenicals; Enzyme Inhibitors; GRB10 Adaptor Protein; GTPase-Activating Proteins; Heterogeneous-Nuclear Ribonucleoproteins; Insulin; Mice; Phosphorylation; Poly U; Proteins; Receptor Protein-Tyrosine Kinases; Ribonucleoproteins; src Homology Domains | 1996 |
Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide.
Topics: Affinity Labels; Animals; Apoptosis; Arsenicals; Cell Line; Cell Nucleus; Chickens; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; HeLa Cells; Humans; Lamin Type A; Lamins; Nuclear Proteins; Phosphoproteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Recombinant Proteins | 1997 |
Activation of the NADPH oxidase in human fibroblasts by mechanical intrusion of a single cell with an ultramicroelectrode.
Topics: Antioxidants; Arsenicals; Cell Line, Transformed; Cell Membrane; Cell Transformation, Viral; Cells, Cultured; Child, Preschool; Enzyme Activation; Enzyme Inhibitors; Fetus; Fibroblasts; Humans; Hydrogen Peroxide; Microelectrodes; NADPH Oxidases; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Simian virus 40; Stress, Mechanical | 1997 |
Agonist-induced internalisation of the angiotensin II-binding sites from plasma membranes of isolated rat hepatocytes.
Topics: Angiotensin II; Animals; Arsenicals; Binding Sites; Calcium; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Ions; Isoelectric Focusing; Isomerism; Liver; Male; Okadaic Acid; Protein Binding; Rats; Rats, Wistar; Receptors, Angiotensin | 1997 |
Neutrophil-associated inflammatory responses in rats are inhibited by phenylarsine oxide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arsenicals; Bronchoalveolar Lavage Fluid; Carrageenan; Edema; Inflammation; Lipopolysaccharides; Male; Neutrophils; Phagocytes; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1997 |
Presence and differential internalization of two distinct insulin-like growth factor receptors in rat hippocampal neurons.
Topics: Animals; Arsenicals; Endocytosis; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Iodine Radioisotopes; Ionophores; Ligands; Monensin; Neurons; Nitriles; Phenols; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Tyrphostins | 1997 |
A characterization of permolybdate and its effect on cellular tyrosine phosphorylation, gap junctional intercellular communication and phosphorylation status of the gap junction protein, connexin43.
Topics: Animals; Arsenicals; Cell Communication; Cells, Cultured; Connexin 43; Cricetinae; Electron Spin Resonance Spectroscopy; Gap Junctions; Hydrogen Peroxide; Molybdenum; Phosphorylation; Protein Tyrosine Phosphatases; Spectrophotometry; Tyrosine | 1997 |
Purified leukocyte cytochrome b558 incorporated into liposomes catalyzes a cytosolic factor dependent diaphorase activity.
Topics: Anaerobiosis; Animals; Arsenicals; Cattle; Cell-Free System; Cytochrome b Group; Cytosol; Detergents; Dihydrolipoamide Dehydrogenase; Horses; Liposomes; Membrane Proteins; NADP; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Solubility; Superoxides; Tetrazolium Salts | 1997 |
Protein tyrosine phosphatases mediate cell readhesion in alveolar epithelial cells mechanically separated from in vitro matrix.
Topics: Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Adhesion Molecules; Cell Separation; Cells, Cultured; Cytoskeletal Proteins; Enzyme Inhibitors; Epithelial Cells; Epithelium; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Male; Mitogen-Activated Protein Kinase 1; Paxillin; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 1997 |
Dimerization is essential for DNA binding and repression by the ArsR metalloregulatory protein of Escherichia coli.
Topics: Amino Acid Sequence; Arsenicals; Bacterial Proteins; Binding Sites; Dimerization; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Methanococcus; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Sequence Deletion; Trans-Activators | 1997 |
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1997 |
Mitogenic activation of the transferrin receptor gene promoter is modulated by inhibitors of tyrosine kinases and tyrosine phosphatases.
Topics: 3T3 Cells; Animals; Arsenicals; Benzoquinones; Cell Division; Gene Expression Regulation; Genistein; Isoflavones; Lactams, Macrocyclic; Mice; Mitogens; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Receptors, Transferrin | 1996 |
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta.
Topics: Arsenicals; Base Sequence; Cell Nucleus; Consensus Sequence; Cyclooxygenase 2; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; NF-kappa B; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Protein Tyrosine Phosphatases; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Receptor-mediated endocytosis of angiotensin II in rat myometrial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arsenicals; Binding, Competitive; Cells, Cultured; Dithiothreitol; Endocytosis; Endosomes; Ethylmaleimide; Female; Myometrium; Rats; Rats, Wistar; Receptors, Angiotensin | 1997 |
A new function for phospholipase C-gamma1: coupling to the adaptor protein GRB2.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Arsenicals; Binding Sites; Cell Line; Cricetinae; Cricetulus; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; GRB2 Adaptor Protein; Immunosorbent Techniques; Isoenzymes; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Recombinant Fusion Proteins; Sulfhydryl Compounds; Type C Phospholipases; Tyrosine | 1997 |
Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B.
Topics: Arsenicals; Cell Adhesion; Cells; Cells, Cultured; Diamide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Monocytes; NF-kappa B; Protein Tyrosine Phosphatases; Signal Transduction; Tumor Necrosis Factor-alpha; Vanadates; Vascular Cell Adhesion Molecule-1 | 1997 |
Phenylarsine oxide inhibits insulin activation of phosphatidylinositol 3'-kinase.
Topics: 3T3 Cells; Adipocytes; Animals; Arsenicals; Biological Transport, Active; Enzyme Activation; Enzyme Inhibitors; Glucose; Insulin; Insulin Antagonists; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins | 1997 |
Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation.
Topics: Arsenicals; Bumetanide; Calcium; Cell Line; Cell Membrane Permeability; Electric Conductivity; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Intestinal Mucosa; Kinetics; Mannitol; Membrane Potentials; Octoxynol; Oxidants; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Intracellular alkalinization causes Mg2+ release from intracellular binding sites in leech Retzius neurones.
Topics: Animals; Arsenicals; Bicarbonates; Binding Sites; Buffers; Carbon Dioxide; Cyclosporine; Hydrogen-Ion Concentration; Leeches; Magnesium; Membrane Potentials; Microelectrodes; Neurons; Propionates; Sodium | 1997 |
Vicinal thiols are involved in inositol 1,2,3,5,6-pentakisphosphate 5-phosphatase activity from fetal calf thymus.
Topics: Animals; Arsenicals; Binding Sites; Cattle; Enzyme Inhibitors; Fetus; Inositol Phosphates; Phosphoric Monoester Hydrolases; Substrate Specificity; Sulfhydryl Compounds; Thymus Gland | 1997 |
[Mechanism of vascular desensitization to agonists].
Topics: Angiotensin II; Animals; Arsenicals; Chloroquine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Tachyphylaxis | 1996 |
Cell locomotion and focal adhesions are regulated by substrate flexibility.
Topics: 3T3 Cells; Acrylic Resins; Animals; Arsenicals; Biomechanical Phenomena; Cell Adhesion; Cell Line; Cell Movement; Collagen; Enzyme Inhibitors; Extracellular Matrix; Mice; Myosins; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Surface Properties; Vinculin | 1997 |
Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase.
Topics: Animals; Aorta, Thoracic; Arsenicals; Enzyme Induction; Enzyme Inhibitors; Genistein; Lipopolysaccharides; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Norepinephrine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Vanadates | 1997 |
Protein tyrosine phosphatase inhibitors in Fc gamma RI-induced myeloid oxidant signaling.
Topics: Arsenicals; Cell Line; Enzyme Inhibitors; Humans; Leukocytes; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, IgG; Respiratory Burst; Signal Transduction; Ubiquitin-Protein Ligases; Vanadates | 1997 |
Ruthenium red-catalyzed degradation of peroxides can prevent mitochondrial oxidative damage induced by either tert-butyl hydroperoxide or inorganic phosphate.
Topics: Animals; Arsenicals; Enzyme Inhibitors; Kinetics; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Stress; Oxygen Consumption; Peroxides; Phosphates; Rats; Rats, Wistar; Reactive Oxygen Species; Ruthenium Red; tert-Butylhydroperoxide | 1998 |
Ca2+ acting at the external side of the inner mitochondrial membrane can stimulate mitochondrial permeability transition induced by phenylarsine oxide.
Topics: Animals; Arsenicals; Calcium; Calcium Channels; Calcium-Binding Proteins; Chelating Agents; Cross-Linking Reagents; Egtazic Acid; Intracellular Membranes; Membrane Potentials; Membrane Proteins; Mitochondria, Liver; Osmolar Concentration; Permeability; Rats; Rats, Wistar; Ruthenium Red; Sulfhydryl Compounds | 1997 |
Oxidant inhibition of alphaLbeta2 integrin adhesion: evidence for coordinate effects on conformation and cytoskeleton linkage.
Topics: Adenosine Triphosphate; Antibodies, Monoclonal; Arsenicals; Cell Adhesion; Cells, Cultured; Cytoskeleton; Humans; Integrins; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Oxidants; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Signal Transduction; Sulfhydryl Compounds; Temperature; Tetradecanoylphorbol Acetate | 1998 |
Phenylarsine oxide as an inhibitor of the activation of the neutrophil NADPH oxidase--identification of the beta subunit of the flavocytochrome b component of the NADPH oxidase as a target site for phenylarsine oxide by photoaffinity labeling and photoina
Topics: Affinity Labels; Animals; Arsenicals; Azides; Cattle; Cell Membrane; Cell-Free System; Cytochrome b Group; Cytosol; Dimerization; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Liposomes; Macromolecular Substances; Molecular Weight; NADPH Oxidases; Neutrophils; Superoxides | 1998 |
[Phenylarsine oxide, a tyrosine phosphatase inhibitor, induces an increase in the intracellular concentration of calcium in rat peritoneal macrophages and human fibroblasts].
Topics: Animals; Arachidonic Acid; Arsenicals; Calcium; Calcium Channel Blockers; Cell Line; Cytoskeleton; Enzyme Inhibitors; Fibroblasts; Humans; Macrophages, Peritoneal; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Sulfhydryl Reagents | 1997 |
Ca2+-independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress.
Topics: Analysis of Variance; Animals; Arsenicals; Calcium; Calmodulin; Carotid Arteries; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Stress, Mechanical; Vasodilation | 1998 |
Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production.
Topics: Animals; Apoptosis; Arsenicals; Cyclosporine; Deoxycholic Acid; Intracellular Membranes; Liver; Male; Membrane Potentials; Mitochondria, Liver; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Ursodeoxycholic Acid | 1998 |
Tumour necrosis factor-alpha-dependent regulation of prostaglandin endoperoxide synthase-2.
Topics: Animals; Arsenicals; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Genistein; Isoenzymes; Mice; Mice, Inbred C57BL; Prostaglandin-Endoperoxide Synthases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA Processing, Post-Transcriptional; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Tyrosine phosphatase-dependent/tyrosine kinase-independent induction of nuclear factor-kappa B by tumor necrosis factor-alpha: effects on prostaglandin endoperoxide synthase-2 mRNA accumulation.
Topics: Arsenicals; Cyclooxygenase 2; Isoenzymes; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Tosylphenylalanyl Chloromethyl Ketone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Arsenicals; Chromones; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Humans; Isoenzymes; Morpholines; Muscarinic Agonists; Phosphatidylinositols; Precipitin Tests; Protein Binding; Receptors, Muscarinic; Subcellular Fractions; Tumor Cells, Cultured; Wortmannin | 1998 |
Fibronectin modulates the effects of HIV-1 Tat on the growth of murine Kaposi's sarcoma-like cells through the down-regulation of tyrosine phosphorylation.
Topics: Animals; Antigens, CD; Arsenicals; Blotting, Western; Cell Division; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Fibronectins; Fluorescent Antibody Technique, Indirect; Gene Products, tat; HIV-1; Integrin alphaV; Integrin beta1; Mice; Mitogen-Activated Protein Kinase 1; Precipitin Tests; Protein Tyrosine Phosphatases; Sarcoma, Kaposi; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Tumor Cells, Cultured | 1998 |
cAMP does not inhibit convulxin-induced tyrosyl-phosphorylation of human platelet proteins, including PLCgamma2, but completely blocks the integrin alphaIIb beta3-dependent dephosphorylation step: comparisons with RGDS peptide, cytochalasin D, and phenyla
Topics: Arsenicals; Blood Proteins; Colforsin; Crotalid Venoms; Cyclic AMP; Cytochalasin D; Enzyme Induction; Humans; In Vitro Techniques; Isoenzymes; Lectins, C-Type; Oligopeptides; Phospholipase C gamma; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Type C Phospholipases; Tyrosine | 1998 |
Effect of inhibition of tyrosine phosphatases on voltage-operated calcium channel currents in rabbit isolated ear artery cells.
Topics: Animals; Arsenicals; Arteries; Calcium Channels; Ear; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen Peroxide; Hydroquinones; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Tyrphostins; Vanadates | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase.
Topics: Arsenicals; Ascorbic Acid; Aurothioglucose; Cell Membrane; Cell-Free System; Dehydroascorbic Acid; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Enzymes; Erythrocytes; Ferricyanides; Glutathione; Glutathione Transferase; Hemolysis; Humans; Ketones; NADP; Thioredoxin-Disulfide Reductase; Vitamin E | 1998 |
Gradual changes in permeability of inner mitochondrial membrane precede the mitochondrial permeability transition.
Topics: Acids; Alkalies; Animals; Arsenicals; Benzoquinones; Hydrogen-Ion Concentration; Intracellular Membranes; Mitochondria, Liver; Permeability; Peroxides; Rats; Rats, Wistar; Sulfhydryl Compounds; tert-Butylhydroperoxide | 1998 |
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.
Topics: Amphiregulin; Animals; Arsenicals; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Mutation; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-4; Receptors, Cell Surface; Thiocarbamates; Thiophenes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Tyrosine phosphorylation of paxillin/pp125FAK and microvascular endothelial barrier function.
Topics: Animals; Arsenicals; Capillary Permeability; Cattle; Cell Adhesion Molecules; Coronary Circulation; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Histamine; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor, Insulin; Swine; Tetradecanoylphorbol Acetate; Venules | 1998 |
Receptor-mediated angiotensin II transcytosis by brain microvessel endothelial cells.
Topics: Angiotensin II; Animals; Arsenicals; Biological Transport, Active; Blood-Brain Barrier; Cattle; Cell Membrane Permeability; Cells, Cultured; Cerebrovascular Circulation; Endothelium, Vascular; Enzyme Inhibitors; Microcirculation; Monensin; Receptors, Angiotensin | 1998 |
Newly synthesized phosphatidylinositol phosphates are required for synaptic norepinephrine but not glutamate or gamma-aminobutyric acid (GABA) release.
Topics: Animals; Arsenicals; Calcium; Chromaffin Cells; Enzyme Inhibitors; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Rats; Synaptosomes | 1998 |
A ubiquinone-binding site regulates the mitochondrial permeability transition pore.
Topics: Animals; Arsenicals; Atractyloside; Binding Sites; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Intracellular Membranes; Ion Channels; Mitochondria, Liver; Molecular Structure; Permeability; Porins; Quinones; Rats; Ubiquinone | 1998 |
DNA binding activity of the aryl hydrocarbon receptor is sensitive to redox changes in intact cells.
Topics: Animals; Arsenicals; Biological Transport; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Diamide; Dimercaprol; DNA-Binding Proteins; DNA, Neoplasm; Mercaptoethanol; Mice; Oxidation-Reduction; Receptors, Aryl Hydrocarbon; Sp1 Transcription Factor; Transcription, Genetic; Tumor Cells, Cultured; Xenobiotics | 1998 |
Fc receptor-mediated phagocytosis requires CDC42 and Rac1.
Topics: Animals; Arsenicals; Bacterial Proteins; Bacterial Toxins; cdc42 GTP-Binding Protein; Cell Cycle Proteins; GTP-Binding Proteins; Leukemia, Basophilic, Acute; Microscopy, Electron; Microscopy, Fluorescence; Mutation; Phagocytosis; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; rac GTP-Binding Proteins; Rats; Receptors, Fc; Transfection; Tumor Cells, Cultured; Zymosan | 1998 |
Phosphotyrosine phosphatase and tyrosine kinase inhibition modulate airway pressure-induced lung injury.
Topics: Air Pressure; Animals; Arsenicals; Blood Pressure; Enzyme Inhibitors; Hemoglobinometry; In Vitro Techniques; Lung; Lung Injury; Male; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Vascular Resistance | 1998 |
Redox regulation of signal transduction in vascular smooth muscle cells: thiol oxidizing agents induced phospholipase D.
Topics: Animals; Arsenicals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; Indoles; Maleimides; Muscle, Smooth, Vascular; Oxidation-Reduction; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Rats; Signal Transduction; Sulfhydryl Compounds; Sulfhydryl Reagents | 1998 |
Inhibition of tumor necrosis factor-alpha- and interleukin-1-induced endothelial E-selectin expression by thiol-modifying agents.
Topics: Acetylcysteine; Arsenicals; Buthionine Sulfoximine; Cells, Cultured; E-Selectin; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Humans; Interleukin-1; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 1998 |
Phenylarsine oxide inhibits ex vivo HIV-1 expression.
Topics: Arsenicals; Cell Line; Enzyme Inhibitors; HIV Core Protein p24; HIV-1; Humans; Hydrogen Peroxide; Lipopolysaccharides; Monocytes; NF-kappa B; Oxidative Stress; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virus Replication | 1997 |
Non-lysosomal cycling pathway for atrial natriuretic peptide activated by protein kinase C in human NPE cells.
Topics: Arsenicals; Atrial Natriuretic Factor; Cell Culture Techniques; Chloroquine; Ciliary Body; Endocytosis; Enzyme Inhibitors; Humans; Lysosomes; Pigment Epithelium of Eye; Protein Kinase C; Temperature; Tetradecanoylphorbol Acetate | 1998 |
Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteins.
Topics: Arsenicals; Cell Division; Enzyme Inhibitors; Gene Products, tat; HeLa Cells; HIV Envelope Protein gp160; HIV-1; Humans; Immunosuppression Therapy; Immunosuppressive Agents; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; tat Gene Products, Human Immunodeficiency Virus | 1999 |
Role of tyrosine phosphorylation in the regulation of cerebral vascular tone in newborn pig in vivo.
Topics: Animals; Animals, Newborn; Arsenicals; Arterioles; Cerebrovascular Circulation; Enzyme Inhibitors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Pia Mater; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Swine; Tyrosine; Vanadates; Vasodilator Agents; Vasomotor System | 1999 |
Purification, characterization, and drug susceptibility of tubulin from Leishmania.
Topics: Animals; Antiprotozoal Agents; Arsenicals; Binding Sites; Dinitrochlorobenzene; Leishmania; Leishmania donovani; Leishmania mexicana; Maytansine; Paclitaxel; Protozoan Proteins; Rats; Species Specificity; Trifluralin; Tubulin | 1999 |
NADPH oxidase inhibition does not interfere with low PO2 transduction in rat and rabbit CB chemoreceptor cells.
Topics: Animals; Arsenicals; Calcium; Carotid Body; Catecholamines; Chemoreceptor Cells; Enzyme Inhibitors; Hypoxia; NADPH Oxidases; Neopterin; Onium Compounds; Oxygen; Partial Pressure; Potassium; Rabbits; Rats; Rats, Sprague-Dawley; Transduction, Genetic | 1999 |
Studies into the effect of tyrosine phosphatase inhibitor phenylarsine oxide on NFkappaB activation in T lymphocytes during aging: evidence for altered IkappaB-alpha phosphorylation and degradation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arsenicals; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; T-Lymphocytes; Tumor Necrosis Factor-alpha | 1999 |
Regulation of the reduced-folate transporter by nitric oxide in cultured human retinal pigment epithelial cells.
Topics: 4-Chloro-7-nitrobenzofurazan; 4-Chloromercuribenzenesulfonate; Antioxidants; Arsenicals; Carrier Proteins; Cells, Cultured; Cyclic GMP; Epithelial Cells; Folate Receptors, GPI-Anchored; Free Radical Scavengers; Humans; Imidazoles; Nitric Oxide; Nitric Oxide Donors; Nitrobenzenes; Oxidation-Reduction; Receptors, Cell Surface; Retinal Pigments; Sulfhydryl Compounds; Tetrahydrofolates; Tetranitromethane; Tyrosine | 1999 |
Phenylarsine oxide and ethanol prevent cell death of porcine polymorphonuclear leucocytes induced by phorbol myristate acetate.
Topics: Animals; Arsenicals; Cell Death; Ethanol; Neutrophils; Protein Kinase C; Superoxides; Swine; Tetradecanoylphorbol Acetate | 1998 |
Phosphatidylinositol 3'-kinase and tyrosine-phosphatase activation positively modulate Convulxin-induced platelet activation. Comparison with collagen.
Topics: Animals; Arsenicals; Blood Platelets; Calcium; Collagen; Crotalid Venoms; Crotalus; Enzyme Activation; Enzyme Inhibitors; Inositol Phosphates; Lectins, C-Type; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Tyrosine | 1999 |
Tyrosine phosphorylation/dephosphorylation controls capping of Fcgamma receptor II in U937 cells.
Topics: Arsenicals; Bacterial Proteins; Benzoquinones; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lactams, Macrocyclic; Microscopy, Fluorescence; Okadaic Acid; Phosphorylation; Quinones; Receptor Aggregation; Receptors, IgG; Rifabutin; Streptolysins; Temperature; Time Factors; Tyrosine; U937 Cells; Vanadates | 1999 |
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
Topics: Arsenicals; Cell Nucleus; Copper; Diamide; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Oxidative Stress; Phenanthrolines; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein Tyrosine Phosphatases; Reactive Oxygen Species; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Topics: Apoptosis; Arsenicals; Arsenites; Caspase Inhibitors; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; U937 Cells | 1999 |
Phenylarsine oxide inhibits phosphate uptake in human ciliary non-pigmented epithelial cells.
Topics: Arsenicals; Biological Transport; Cell Line, Transformed; Cell Membrane; Ciliary Body; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Humans; Hydroxymercuribenzoates; Phosphates; Phosphorylation; Protease Inhibitors; Sodium; Time Factors | 1999 |
Evidence for phosphatidylinositol 4-kinase and actin involvement in the regulation of 125I-beta-nerve growth factor retrograde axonal transport.
Topics: 1-Phosphatidylinositol 4-Kinase; Actins; Animals; Arsenicals; Axonal Transport; Cell Survival; Cytoskeleton; Enzyme Inhibitors; Iodine Radioisotopes; Isoenzymes; Male; Mice; Mice, Inbred CBA; Nerve Growth Factors; Neurons; Neurons, Afferent; Signal Transduction; Superior Cervical Ganglion | 1999 |
Multiple effects of mercuric chloride on hexose transport in Xenopus oocytes.
Topics: Animals; Arsenicals; Biological Transport; Cell Size; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hexoses; Insulin; Kinetics; Mannitol; Mercuric Chloride; Oocytes; Up-Regulation; Water; Xenopus laevis | 1999 |
Chloromethyltetramethylrosamine (Mitotracker Orange) induces the mitochondrial permeability transition and inhibits respiratory complex I. Implications for the mechanism of cytochrome c release.
Topics: Animals; Arsenicals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cytochrome c Group; Electron Transport Complex I; Ethylmaleimide; Fluorescent Dyes; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; NADH, NADPH Oxidoreductases; Permeability; Rats; Rats, Wistar; Rhodamines; Xanthenes | 1999 |
Localized depolymerization of the major sperm protein cytoskeleton correlates with the forward movement of the cell body in the amoeboid movement of nematode sperm.
Topics: Actin Cytoskeleton; Animals; Arsenicals; Ascaris suum; Cell Adhesion; Cell Membrane; Cell Size; Cytoskeleton; Glass; Helminth Proteins; Hydrogen-Ion Concentration; Kinetics; Male; Polymers; Protein Tyrosine Phosphatases; Pseudopodia; Sperm Head; Sperm Motility; Spermatozoa | 1999 |
NO alters cell shape and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B activation.
Topics: Animals; Aorta; Arsenicals; Cell Movement; Cell Size; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley | 1999 |
Arsenic disrupts cellular levels of p53 and mdm2: a potential mechanism of carcinogenesis.
Topics: Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Cell Line; Cell Transformation, Neoplastic; Humans; Keratinocytes; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Teratogens; Tumor Suppressor Protein p53 | 1999 |
Induction of the non-selective mitochondrial pore in lymphoid cells. 1. Permeabilized rat thymocytes.
Topics: Animals; Arsenicals; Calcimycin; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane Permeability; Cyclosporine; Digitonin; Enzyme Inhibitors; In Vitro Techniques; Intracellular Membranes; Mitochondria; Oxygen Consumption; Rats; T-Lymphocytes; tert-Butylhydroperoxide; Thymus Gland; Uncoupling Agents | 1999 |
Induction of the non-selective mitochondrial pore in lymphoid cells. 2. Intact rat thymocytes.
Topics: Animals; Arsenicals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cross-Linking Reagents; Cyclosporine; Cytosol; In Vitro Techniques; Intracellular Membranes; Membrane Potentials; Mitochondria; Permeability; Rats; T-Lymphocytes; tert-Butylhydroperoxide; Thymus Gland | 1999 |
Phenylarsine oxide blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Arsenicals; Caspase 3; Caspase Inhibitors; Cell Division; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Interleukin-1; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Protein Tyrosine Phosphatases; Transcription, Genetic; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Corticotropin increases protein tyrosine phosphatase activity by a cAMP-dependent mechanism in rat adrenal gland.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arsenicals; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Male; Molecular Weight; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Signal Transduction; Subcellular Fractions; Vanadates; Zona Fasciculata | 1999 |
Modulation of tau phosphorylation within its microtubule-binding domain by cellular thiols.
Topics: Animals; Arsenicals; Binding Sites; Cells, Cultured; Cerebral Cortex; Cytoskeleton; Enzyme Inhibitors; Humans; Microtubules; Neuroblastoma; Oxidants; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Staurosporine; Sulfhydryl Compounds; tau Proteins; Tumor Cells, Cultured | 1999 |
Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate.
Topics: Androstadienes; Animals; Arsenicals; Cell Adhesion Molecules; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Myosin-Light-Chain Kinase; Neuroblastoma; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Cholinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1999 |
Phenylarsine oxide increases intracellular calcium mobility and inhibits Ca(2+)-dependent ATPase activity in thymocytes.
Topics: Animals; Arsenicals; Calcium; Calcium-Transporting ATPases; Cell Membrane Permeability; Enzyme Inhibitors; HIV-1; Humans; In Vitro Techniques; Kinetics; Male; Mice; Microsomes; Muscle, Skeletal; Organelles; Sarcoplasmic Reticulum; T-Lymphocytes; Virus Replication | 1999 |
Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition.
Topics: Arsenicals; beta Catenin; Cadherins; Cell Membrane Permeability; Cells, Cultured; Cytoskeletal Proteins; Endothelium, Vascular; Enzyme Inhibitors; Humans; Kinetics; Membrane Proteins; Metalloendopeptidases; Occludin; Phenanthrolines; Phosphoproteins; Protein Tyrosine Phosphatases; Substrate Specificity; Trans-Activators; Umbilical Veins; Zonula Occludens-1 Protein | 1999 |
Altered actin cytoskeleton and inhibition of matrix metalloproteinase expression by vanadate and phenylarsine oxide, inhibitors of phosphotyrosine phosphatases: modulation of migration and invasion of human malignant glioma cells.
Topics: Actins; Arsenicals; Cell Adhesion Molecules; Cell Movement; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Glioma; Humans; Matrix Metalloproteinases; Neoplasm Invasiveness; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1999 |
Phenylarsine oxide evokes intracellular calcium increases and amylase secretion in isolated rat pancreatic acinar cells.
Topics: Amylases; Animals; Arsenicals; Calcium; Cells, Cultured; Enzyme Inhibitors; Intracellular Fluid; Male; Pancreas; Rats; Rats, Wistar; Sincalide | 1999 |
Kinetic study of the activation of the neutrophil NADPH oxidase by arachidonic acid. Antagonistic effects of arachidonic acid and phenylarsine oxide.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arsenicals; Cattle; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Esters; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; NADP; NADPH Oxidases; Neutrophils; Oxygen; Time Factors | 1999 |
Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells.
Topics: Acetylcysteine; Animals; Arsenicals; Binding, Competitive; Cells, Cultured; Chick Embryo; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Genes, Reporter; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Liver; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc; Response Elements; Transcription Factor AP-1; Transfection | 1999 |
ATP treatment of human monocytes promotes caspase-1 maturation and externalization.
Topics: Adenosine Triphosphate; Arsenicals; Caspase 1; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Activation; Ethylmaleimide; Humans; Interleukin-1; Lipopolysaccharides; Monocytes; Protein Processing, Post-Translational | 1999 |
Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.
Topics: Amino Acid Sequence; Animals; Arsenicals; Chromosome Mapping; Cloning, Molecular; Flavoproteins; Humans; In Situ Hybridization, Fluorescence; Molecular Sequence Data; NADPH Oxidases; RNA, Messenger; Swine; Thyroid Gland | 1999 |
alpha-Difluoromethylornithine blocks thymocyte apoptosis via a reduction in tyrosine phosphorylation.
Topics: Animals; Apoptosis; Arsenicals; Cells, Cultured; Dexamethasone; Eflornithine; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Signal Transduction; T-Lymphocytes; Thymus Gland | 1999 |
Interleukin-1 signaling is dependent on free thiols.
Topics: Animals; Arsenicals; Cells, Cultured; Diamide; Endothelium, Vascular; Enzyme Inhibitors; Humans; Interleukin-1; Mice; Molecular Weight; NF-kappa B; Oxidation-Reduction; Phosphorylation; Receptors, Interleukin-1; Receptors, Interleukin-1 Type I; Signal Transduction; Sulfhydryl Compounds; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured; Umbilical Veins; Vitamin K | 1999 |
Vicinal dithiol-binding agent, phenylarsine oxide, inhibits inducible nitric-oxide synthase gene expression at a step of nuclear factor-kappaB DNA binding in hepatocytes.
Topics: Animals; Arsenicals; Cells, Cultured; Dimercaprol; DNA-Binding Proteins; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, Reporter; Interleukin-1; Liver; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; RNA, Messenger; Sulfhydryl Compounds; Transcriptional Activation; Transfection | 2000 |
Phenylarsine oxide inhibits the fusicoccin-induced activation of plasma membrane H(+)-ATPase.
Topics: Arsenicals; Brassica; Cell Membrane; Enzyme Activation; Glycosides; Proton-Translocating ATPases | 2000 |
Inactivation of calcineurin by hydrogen peroxide and phenylarsine oxide. Evidence for a dithiol-disulfide equilibrium and implications for redox regulation.
Topics: Animals; Arsenicals; Calcineurin Inhibitors; Cattle; Disulfides; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hydrogen Peroxide; Oxidation-Reduction; Toluene | 2000 |
The fibronectin-derived anti-adhesive peptide III14-2 suppresses adhesion and apoptosis of leukemic cell lines through down-regulation of protein-tyrosine phosphorylation.
Topics: Apoptosis; Arsenicals; Cell Adhesion; DNA Fragmentation; Down-Regulation; Fibronectins; Genistein; HL-60 Cells; Humans; K562 Cells; Microscopy, Fluorescence; Peptide Fragments; Phosphorylation; Phosphotyrosine; Receptors, Fibronectin | 2000 |
Pitfalls of using lucigenin in endothelial cells: implications for NAD(P)H dependent superoxide formation.
Topics: Acridines; Arsenicals; Cells, Cultured; Cytochrome c Group; Imidazoles; Luminescent Measurements; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Onium Compounds; Pyrazines; Superoxides; Umbilical Veins; Xanthine; Xanthine Oxidase | 2000 |
Microtubule/MAP-affinity regulating kinase (MARK) is activated by phenylarsine oxide in situ and phosphorylates tau within its microtubule-binding domain.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenicals; Binding Sites; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Microtubules; Neuroblastoma; Neurons; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Rats; Serine; tau Proteins; Tumor Cells, Cultured | 2000 |
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes.
Topics: Arsenicals; CD18 Antigens; Cell Aggregation; Dimercaprol; Enzyme-Linked Immunosorbent Assay; Eosinophils; Humans; Hydroxamic Acids; L-Selectin; Leukocytes; Lymphocyte Activation; Lymphocytes; Neutrophil Activation; Neutrophils; Protein Binding; Solubility; Sulfhydryl Reagents | 2000 |
Protein-tyrosine phosphatase reduces the number of apical small conductance K+ channels in the rat cortical collecting duct.
Topics: Animals; Arsenicals; Benzoquinones; Brefeldin A; Colchicine; Concanavalin A; Diet; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Kidney Tubules, Collecting; Lactams, Macrocyclic; Male; Paclitaxel; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Small-Conductance Calcium-Activated Potassium Channels | 2000 |
The phosphatidylinositol 4-kinase inhibitor phenylarsine oxide blocks evoked neurotransmitter release by reducing calcium entry through N-type calcium channels.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Arsenicals; Calcium; Calcium Channels, N-Type; Chelating Agents; Dimercaprol; Drug Interactions; Enzyme Inhibitors; Ganglia, Sympathetic; In Vitro Techniques; Motor Neurons; Neurotransmitter Agents; Rana pipiens | 2000 |
Processing by endoplasmic reticulum mannosidases partitions a secretion-impaired glycoprotein into distinct disposal pathways.
Topics: alpha 1-Antitrypsin; Animals; Arsenicals; Carbohydrate Sequence; Endoplasmic Reticulum; Genetic Variation; Glycoproteins; Humans; Liver Neoplasms, Experimental; Mannosidases; Mice; Molecular Sequence Data; Okadaic Acid; Oligosaccharides; Recombinant Proteins; Sodium Fluoride; Transfection; Tumor Cells, Cultured; Vanadates | 2000 |
Inhibition of mitochondrial permeability transition by low pH is associated with less extensive membrane protein thiol oxidation.
Topics: Animals; Antimycin A; Arsenicals; Calcimycin; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Diethyl Pyrocarbonate; Hydrogen-Ion Concentration; Hydroxylamine; Intracellular Membranes; Ionophores; Membrane Proteins; Mitochondria, Liver; Oxidation-Reduction; Permeability; Rats; Rats, Wistar; Serum Albumin, Bovine; Sulfhydryl Compounds | 1999 |
A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms.
Topics: Animals; Arsenicals; Arsenites; Carmustine; CHO Cells; Cricetinae; Cystine; Diamide; Disulfides; Dithionitrobenzoic Acid; Glutathione; Humans; Oxidation-Reduction; Rats; Selenium Compounds; Selenium Oxides; Sulfhydryl Compounds; Thioctic Acid; Tumor Cells, Cultured | 2000 |
Significance of ROS in oxygen chemoreception in the carotid body chemoreception. Apparent lack of a role for NADPH oxidase.
Topics: Animals; Arsenicals; Carotid Body; Catecholamines; Cell Hypoxia; Chemoreceptor Cells; Enzyme Inhibitors; In Vitro Techniques; Models, Neurological; NADPH Oxidases; Neopterin; Onium Compounds; Oxygen; Rabbits; Reactive Oxygen Species; Signal Transduction | 2000 |
Characterization of iron uptake from transferrin by murine endothelial cells.
Topics: Animals; Anti-Bacterial Agents; Arsenicals; Blood-Brain Barrier; Brain; Cell Line; Endocytosis; Endothelium; Enzyme Inhibitors; Ethylmaleimide; Ferric Compounds; Iron; Iron Chelating Agents; Lipopolysaccharides; Lymph Nodes; Macrolides; Mice; Receptors, Transferrin; Transferrin; Tumor Necrosis Factor-alpha | 2000 |
G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide.
Topics: Animals; Arsenicals; Cell Division; Cell Line; Cricetinae; Cricetulus; Dehydroepiandrosterone; Disulfides; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutathione; Oxidation-Reduction; Pentose Phosphate Pathway; Sulfhydryl Compounds | 2000 |
Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria.
Topics: Animals; Arsenicals; Brain; Calcium; Clonazepam; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Intercellular Signaling Peptides and Proteins; Ion Channels; Liver; Male; Membrane Proteins; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Peptides; Phosphates; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Thiazepines; Wasp Venoms | 2000 |
Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity.
Topics: Animals; Arsenicals; Depression, Chemical; Down-Regulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tyrosine; Vanadates | 2000 |
Inhibitors of tyrosine phosphatases block angiotensin II inhibition of Na(+) pump.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arsenicals; Enzyme Inhibitors; Female; Naphthalenes; Phospholipases A; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetramisole; Tyrosine | 2000 |
Phenylarsine oxide inhibits heat shock protein 70 induction in cultured guinea pig gastric mucosal cells.
Topics: Animals; Arsenicals; Cell Nucleus; Cells, Cultured; Dimercaprol; DNA-Binding Proteins; Gastric Mucosa; Guinea Pigs; Heat Shock Transcription Factors; Heat Stress Disorders; HSP70 Heat-Shock Proteins; Male; Mercaptoethanol; Phosphorylation; Promoter Regions, Genetic; Protein Biosynthesis; RNA, Messenger; Thioredoxins; Transcription Factors; Tyrosine | 2000 |
Disruption of cell-substrate adhesion activates the protein tyrosine kinase pp60(c-src).
Topics: Animals; Arsenicals; Cell Adhesion; Cells, Cultured; Chick Embryo; Cytochalasin D; Enzyme Inhibitors; Fibroblasts; Fibronectins; Focal Adhesion Protein-Tyrosine Kinases; Phosphorylation; Polylysine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Trypsin; Tyrosine | 2000 |
Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane.
Topics: Arsenicals; Carbocyanines; Cell Membrane; Diffusion; Dimerization; Endocytosis; Energy Transfer; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Fluorescence; Fluorescent Dyes; Green Fluorescent Proteins; Humans; Immunoglobulin Fab Fragments; Ligands; Luminescent Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Microspheres; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Signal Transduction; Tumor Cells, Cultured | 2000 |
Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor.
Topics: Alkylating Agents; Animals; Arsenicals; CHO Cells; Cloning, Molecular; Cricetinae; Down-Regulation; Endocytosis; Guinea Pigs; Kinetics; Neuropeptide Y; Pancrelipase; Rats; Receptors, Neuropeptide Y; Subcellular Fractions; Sucrose; Temperature; Transfection | 2001 |
Inhibition of human squalene monooxygenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls.
Topics: Arsenicals; Enzyme Inhibitors; Humans; Oxygenases; Squalene Monooxygenase; Sulfhydryl Compounds; Tellurium | 2001 |
Presence of closely spaced protein thiols on the surface of mammalian cells.
Topics: Animals; Arsenicals; Biotin; Electrophoresis, Polyacrylamide Gel; Endothelium; Fibrosarcoma; Glutathione; Humans; Indicators and Reagents; Mammals; Membrane Proteins; Oxidation-Reduction; Protein Disulfide-Isomerases; Sulfhydryl Compounds; Thioredoxins | 2000 |
Angiotensin II receptor internalization and signaling in isolated rat hepatocytes.
Topics: Angiotensin II; Animals; Arsenicals; Cells, Cultured; Endocytosis; Enzyme Inhibitors; Hepatocytes; Male; Okadaic Acid; Rats; Rats, Wistar; Receptors, Angiotensin; Second Messenger Systems; Signal Transduction; Time Factors | 1999 |
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.
Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates | 2001 |
Phenylarsine oxide inhibits nitric oxide synthase in pulmonary artery endothelial cells.
Topics: Animals; Aorta; Arsenicals; Cattle; Cell Membrane; Cells, Cultured; Cloning, Molecular; Dithiothreitol; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphotyrosine; Protein Tyrosine Phosphatases; Pulmonary Artery; Recombinant Proteins; Swine | 2000 |
Phenylarsine oxide induces mitochondrial permeability transition, hypercontracture, and cardiac cell death.
Topics: Adenosine Triphosphate; Animals; Arsenicals; Biological Transport; Calcium; Cell Death; Chelating Agents; Dithiothreitol; Egtazic Acid; Enzyme Inhibitors; Heart Ventricles; In Vitro Techniques; Intracellular Membranes; Mitochondria; Muscle Fibers, Skeletal; Myocardial Reperfusion Injury; Myocardium; Myofibrils; Rabbits; Sarcolemma | 2001 |
Internalization of [3H]substance P analogues in NK-1 receptor transfected CHO cells.
Topics: Animals; Arsenicals; CHO Cells; Cricetinae; Endocytosis; Kinetics; Models, Biological; Monensin; Peptide Fragments; Receptors, Neurokinin-1; Substance P; Temperature; Transfection | 2001 |
NADPH oxidase does not account fully for O2-sensing in model airway chemoreceptor cells.
Topics: Arsenicals; Cell Hypoxia; Cell Line; Chemoreceptor Cells; Enzyme Inhibitors; Humans; Kinetics; Membrane Potentials; NADPH Oxidases; Onium Compounds; Oxygen; Patch-Clamp Techniques; Potassium Channels; Reactive Oxygen Species | 2001 |
Evidence of pituitary adenylate cyclase activating polypeptide (PACAP) in pancreatic islet cells by confocal microscopy.
Topics: Animals; Arsenicals; Cell Compartmentation; Cell Nucleus; Cell Separation; Endocytosis; Image Processing, Computer-Assisted; Islets of Langerhans; Male; Microscopy, Confocal; Microscopy, Fluorescence; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Specimen Handling | 2001 |
A phenylarsine oxide-binding protein of neutrophil cytosol, which belongs to the S100 family, potentiates NADPH oxidase activation.
Topics: Animals; Antigens, Differentiation; Arsenicals; Azides; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cattle; Cell-Free System; Chromatography, Affinity; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Macromolecular Substances; NADPH Oxidases; Neutrophil Activation; Neutrophils; Photoaffinity Labels; Protein Binding; S100 Proteins; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Effects of phosphoprotein phosphatase inhibitors (phenylarsine oxide and cantharidin) on Tetrahymena.
Topics: Actins; Animals; Arsenicals; Cantharidin; Cytoskeleton; Enzyme Inhibitors; Glucosamine; Glycolipids; Mannose; Membrane Lipids; Microscopy, Confocal; Microscopy, Electron, Scanning; Palmitic Acid; Phagocytosis; Phosphatidylinositols; Phospholipids; Phosphoprotein Phosphatases; Signal Transduction; Tetrahymena pyriformis; Tubulin | 2001 |
Inhibition of protein tyrosine phosphatases suppresses P-selectin exocytosis in activated human platelets.
Topics: Arsenicals; Blood Platelets; Cell Adhesion; Cells, Cultured; Diamide; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; HL-60 Cells; Humans; Immunohistochemistry; Neutrophils; P-Selectin; Platelet Activation; Protein Tyrosine Phosphatases; Rosette Formation | 2001 |
Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide.
Topics: Androstadienes; Arsenicals; Deferoxamine; Genistein; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Kidney; Kidney Tubules, Proximal; Nitric Oxide; Oxygen; Phosphorylation; Protein Serine-Threonine Kinases; Protein Subunits; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Transcription Factors; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2001 |
Inhibition of protein tyrosine phosphatases suppresses P-selectin exocytosis in activated human platelets.
Topics: Arsenicals; Blood Platelets; Cell Adhesion; Cells, Cultured; Diamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; HL-60 Cells; Humans; Neutrophils; P-Selectin; Platelet Activation; Protein Tyrosine Phosphatases; Rosette Formation | 2001 |
14-3-3 protein-activated and autoinhibited forms of plasma membrane H(+)-ATPase.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Arsenicals; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Ethylmaleimide; Glycosides; Glycosylation; Hydrogen-Ion Concentration; Immunoblotting; Models, Biological; Molecular Sequence Data; Phosphorylation; Phosphothreonine; Phosphotyrosine; Plant Proteins; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proton-Translocating ATPases; Sequence Homology, Amino Acid; Tyrosine 3-Monooxygenase | 2001 |
Cell locomotion and focal adhesions are regulated by the mechanical properties of the substrate.
Topics: Acrylic Resins; Animals; Arsenicals; Biomechanical Phenomena; Cell Adhesion; Cell Line; Cell Movement; Culture Media; Diacetyl; Enzyme Inhibitors; Epithelial Cells; Fibroblasts; Kidney; Membrane Glycoproteins; NADPH Oxidases; Rats; Signal Transduction; Surface Properties | 1998 |
IL-3 induces down-regulation of CCR3 protein and mRNA in human eosinophils.
Topics: Androstadienes; Animals; Arsenicals; Calcium Signaling; Cells, Cultured; Chemokine CCL11; Chemokines, CC; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Endocytosis; Enzyme Inhibitors; Eosinophils; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-3; Interleukins; Luminescent Measurements; Mice; Receptors, CCR3; Receptors, Chemokine; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Wortmannin | 2001 |
Effects of protein tyrosine kinase and protein tyrosine phosphatase on apical K(+) channels in the TAL.
Topics: Amides; Animals; Arsenicals; Benzoquinones; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Female; Hydroxyeicosatetraenoic Acids; Hyperkalemia; Hypokalemia; Lactams, Macrocyclic; Loop of Henle; Male; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Sodium; Specific Pathogen-Free Organisms; src-Family Kinases; Sulfones | 2001 |
Inhibition of phosphatidylinositol 4-kinase results in a significant reduced respiratory burst in formyl-methionyl-leucyl-phenylalanine-stimulated human neutrophils.
Topics: 1-Phosphatidylinositol 4-Kinase; Antibodies, Monoclonal; Arsenicals; Enzyme Inhibitors; Fluorescent Dyes; Humans; Luminescent Measurements; Luminol; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxadiazoles; Respiratory Burst | 2001 |
Translation of chloroplast psbA mRNA is regulated by signals initiated by both photosystems II and I.
Topics: Animals; Arsenicals; Chlamydomonas reinhardtii; Chloroplasts; Electron Transport; Gene Expression Regulation, Plant; NADPH Oxidases; Oxidation-Reduction; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Photosystem II Protein Complex; Plastoquinone; Protein Biosynthesis; RNA, Messenger; Signal Transduction; Toluene | 2001 |
Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells.
Topics: Animals; Anisoles; Arsenicals; Biological Transport; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Haloperidol; Hydroquinones; Kinetics; Ligands; Neurons; Ouabain; Pentazocine; Piperazines; Propylamines; Pyrrolidines; Rats; Receptors, sigma; Sigma-1 Receptor; Sodium; Sulfonamides; Tartrates; Thapsigargin; Time Factors; Tritium | 2001 |
Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury.
Topics: Acidosis; Animals; Arsenicals; Brain; Calcium; Energy Metabolism; Enzyme Inhibitors; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Phosphates; Rats; Rats, Wistar; Reperfusion Injury | 2001 |
Staining of cellular mitochondria with LDS-751.
Topics: Animals; Arsenicals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Digitonin; Fluorescent Dyes; Membrane Potentials; Mice; Microscopy, Confocal; Mitochondria; Monocytes; Organic Chemicals; Rhodamine 123; Staining and Labeling | 2001 |
H(2)O(2)-mediated permeability II: importance of tyrosine phosphatase and kinase activity.
Topics: Animals; Arsenicals; beta Catenin; Cadherins; Cattle; Cell Membrane Permeability; Cytoskeletal Proteins; Cytoskeleton; Endocytosis; Endothelium, Vascular; Enzyme Inhibitors; Hydrogen Peroxide; Oxidants; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pulmonary Artery; src-Family Kinases; Trans-Activators | 2001 |
Hydrogen peroxide is a regulator of ABI1, a protein phosphatase 2C from Arabidopsis.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Arsenicals; Cysteine; Enzyme Inhibitors; Glutathione; Hydrogen Peroxide; Kinetics; Methionine; Oxidation-Reduction; Phosphoprotein Phosphatases; Protein Phosphatase 2; Protein Phosphatase 2C; Saccharomyces cerevisiae Proteins; Signal Transduction | 2001 |
Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells.
Topics: Actins; Animals; Arsenicals; Blotting, Western; Cells, Cultured; Chick Embryo; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; L-Lactate Dehydrogenase; Liver; Phosphorylation; Protein Isoforms; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Stress, Physiological; Sulfhydryl Compounds; Time Factors; Up-Regulation; ZAP-70 Protein-Tyrosine Kinase | 2001 |
GSH is required to recycle ascorbic acid in cultured liver cell lines.
Topics: Animals; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Kinetics; Liver; Maleates; NADP; Rats; Thioredoxin-Disulfide Reductase; Time Factors; Water | 2001 |
Force transduction by Triton cytoskeletons.
Topics: Animals; Arsenicals; Cell Line; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Cytoskeleton; Detergents; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; L Cells; Mice; Octoxynol; Paxillin; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma-Like Protein p130; Signal Transduction; Stress, Mechanical; Vinculin | 2002 |
PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow.
Topics: Arsenicals; Blotting, Western; Cell Adhesion; Cell Size; Collagen; Colonic Neoplasms; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Oligonucleotides, Antisense; Paxillin; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; PTEN Phosphohydrolase; Rheology; Stress, Mechanical; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Internalization of metabotropic glutamate receptor in C6 cells through clathrin-coated vesicles.
Topics: Amino Acid Transport System X-AG; Animals; Arsenicals; Binding Sites; Cell Membrane; Central Nervous System; Clathrin-Coated Vesicles; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Neurons; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Sucrose; Synaptic Transmission; Tumor Cells, Cultured | 2002 |
Independence of angiotensin II-induced MAP kinase activation from angiotensin type 1 receptor internalization in clone 9 hepatocytes.
Topics: Angiotensin II; Animals; Arsenicals; Cell Line; Concanavalin A; COS Cells; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Hepatocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Quinazolines; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sucrose; Transfection; Tyrphostins | 2002 |
Activation and inactivation of signal transducers and activators of transcription by ciliary neurotrophic factor in neuroblastoma cells.
Topics: Animals; Antigens, CD; Arsenicals; Cells, Cultured; Chick Embryo; Ciliary Neurotrophic Factor; Cytokine Receptor gp130; Cytokines; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Humans; Kinetics; Membrane Glycoproteins; Neuroblastoma; Neurons; Protein Kinases; Protein Tyrosine Phosphatases; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2002 |
The sensitivity of ABI2 to hydrogen peroxide links the abscisic acid-response regulator to redox signalling.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Arsenicals; Fatty Acids, Nonesterified; Glutathione; Hydrogen Peroxide; Hydrogen-Ion Concentration; Magnesium; Manganese; Oxidation-Reduction; Phosphoprotein Phosphatases; Signal Transduction | 2002 |
Phenylarsine oxide affinity chromatography to identify proteins involved in redox regulation: dithiol-disulfide equilibrium in serine/threonine phosphatase calcineurin.
Topics: Animals; Arsenicals; Brain; Calcineurin; Calcineurin Inhibitors; Cattle; Chromatography, Affinity; Disulfides; Enzyme Inhibitors; Hydrogen Peroxide; In Vitro Techniques; Oxidation-Reduction; Sulfhydryl Compounds | 2002 |
Entamoeba histolytica-induced dephosphorylation in host cells.
Topics: Animals; Apoptosis; Arsenicals; CHO Cells; Cricetinae; Dipeptides; Entamoeba histolytica; Enzyme Activation; Humans; Jurkat Cells; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Tyrosine | 2002 |
Phosphatidylinositol kinase enzymes regulate the retrograde axonal transport of NT-3 and NT-4 in sympathetic and sensory neurons.
Topics: Androstadienes; Animals; Arsenicals; Axonal Transport; Biological Transport, Active; Chromones; Enzyme Inhibitors; Female; Iris; Male; Mice; Mice, Inbred BALB C; Morpholines; Nerve Growth Factors; Neurons; Neurons, Afferent; Neurotrophin 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptor, trkA; Sympathetic Nervous System; Tyrphostins; Wortmannin | 2002 |
A pool of Y2 neuropeptide Y receptors activated by modifiers of membrane sulfhydryl or cholesterol balance.
Topics: Animals; Arsenicals; Cell Membrane; CHO Cells; Cholesterol; Cricetinae; Ethylmaleimide; Filipin; Guinea Pigs; Mesylates; Receptors, Neuropeptide Y | 2002 |
Analysing c-kit internalization using a functional c-kit-EGFP chimera containing the fluorochrome within the extracellular domain.
Topics: Animals; Arsenicals; beta-Cyclodextrins; Blotting, Western; Cell Line; Cholesterol; Cloning, Molecular; COS Cells; Cyclodextrins; Cysteine Endopeptidases; Dimerization; Endocytosis; Endosomes; Enzyme Activation; Flow Cytometry; Green Fluorescent Proteins; Luminescent Proteins; Membrane Microdomains; Microscopy, Fluorescence; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-kit; Recombinant Fusion Proteins; Time Factors; Tyrosine | 2002 |
Cytoplasmic transport of Stat3 by receptor-mediated endocytosis.
Topics: 3T3 Cells; Active Transport, Cell Nucleus; Adaptor Proteins, Vesicular Transport; Animals; Arsenicals; Carrier Proteins; Clathrin; Coated Pits, Cell-Membrane; DNA-Binding Proteins; Endocytosis; Endosomes; Epidermal Growth Factor; ErbB Receptors; Genes, Reporter; Membrane Proteins; Mice; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Proteins; Recombinant Fusion Proteins; STAT3 Transcription Factor; Trans-Activators; Transfection | 2002 |
Arachidonic acid release and prostaglandin F2alpha formation induced by phenylarsine oxide in PC12 cells: possible involvement of secretory phospholipase A2 activity.
Topics: Animals; Arachidonic Acid; Arsenicals; Calcium; Carrier Proteins; Dinoprost; Drug Interactions; Enzyme Activation; Group II Phospholipases A2; Neurons; PC12 Cells; Phospholipases A; Phospholipases A2; Rats; Receptors, Cell Surface; Receptors, Phospholipase A2; Reverse Transcriptase Polymerase Chain Reaction; Toluene | 2002 |
Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons.
Topics: Animals; Arsenicals; Calcium; Calcium Channels; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Compartmentation; Cerebral Cortex; Cytosol; Dinitrophenols; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracellular Membranes; Ion Channel Gating; Ion Transport; Ionophores; Membrane Potentials; Mice; Mitochondria; Nerve Tissue Proteins; Neurons; Potassium; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Synaptic Vesicles; Thapsigargin; Uncoupling Agents; Valinomycin; Zinc | 2002 |
Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling.
Topics: Animals; Arsenicals; Binding Sites; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Endosomes; Filipin; Guinea Pigs; Iodine Radioisotopes; Kinetics; Neuropeptide Y; Receptors, Neuropeptide Y; Sucrose; Temperature | 2002 |
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore.
Topics: Adenosine Diphosphate; Animals; Arsenicals; Chromatography, Affinity; Cross-Linking Reagents; Cyclophilins; Cysteine; Diamide; Dimerization; Eosine Yellowish-(YS); Glutathione Transferase; Intracellular Membranes; Male; Mitochondria; Mitochondrial ADP, ATP Translocases; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Permeability; Phenanthrolines; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfhydryl Reagents | 2002 |
Early events of TCR signaling are distinct in human Th1 and Th2 cells.
Topics: Antibodies, Monoclonal; Arsenicals; CD28 Antigens; CD3 Complex; Cell Line; Dimerization; Enzyme Inhibitors; HeLa Cells; HLA-DR1 Antigen; Humans; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Signal Transduction; Th1 Cells; Th2 Cells; Tyrosine; Up-Regulation; ZAP-70 Protein-Tyrosine Kinase | 2002 |
Functional involvement of src and focal adhesion kinase in a CD99 splice variant-induced motility of human breast cancer cells.
Topics: 12E7 Antigen; Antigens, CD; Arsenicals; Breast Neoplasms; Cell Adhesion Molecules; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Signal Transduction; src-Family Kinases; Transfection; Tumor Cells, Cultured | 2002 |
Simultaneous in situ monitoring of intracellular Ca2+ and NO in endothelium of coronary arteries.
Topics: Animals; Arsenicals; Bradykinin; Calcium; Cattle; Chelating Agents; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; In Vitro Techniques; Intracellular Fluid; Ionophores; Microscopy, Fluorescence; Nitric Oxide; Protein Tyrosine Phosphatases | 2002 |
The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation.
Topics: Acetylcysteine; Acute Disease; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Cell Transformation, Viral; Enzyme Activation; Gene Expression Regulation, Viral; Granulocyte-Macrophage Colony-Stimulating Factor; Herpesvirus 8, Human; Humans; I-kappa B Proteins; Leukemia, Myeloid; Leupeptins; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; NF-kappa B; Oxides; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Recombinant Proteins; Rhadinovirus; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Viral Proteins | 2003 |
Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine Triphosphate; Animals; Arsenicals; Calcium Signaling; Calcium-Binding Proteins; Drosophila; Enzyme Inhibitors; Exocytosis; Ionomycin; Membrane Potentials; Neuronal Calcium-Sensor Proteins; Neuropeptides; Neurosecretory Systems; PC12 Cells; Pheochromocytoma; Rats; Type C Phospholipases; Xenopus | 2003 |
Protein tyrosine phosphatases are involved in LH/chorionic gonadotropin and 8Br-cAMP regulation of steroidogenesis and StAR protein levels in MA-10 Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androgens; Animals; Arsenicals; Cholesterol; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Leydig Cells; Male; Mice; Phosphoproteins; Protein Tyrosine Phosphatases; RNA, Messenger; Signal Transduction; Time Factors; Tumor Cells, Cultured | 2002 |
Redox control of platelet aggregation.
Topics: Arsenicals; Disulfides; Drug Synergism; Glutathione; Glutathione Disulfide; Humans; Oxidation-Reduction; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Subunits; Sulfhydryl Compounds; Unithiol | 2003 |
The obligatory action of protein tyrosine phosphatases in ACTH-stimulated steroidogenesis is exerted at the level of StAR protein.
Topics: Adrenocorticotropic Hormone; Animals; Arsenicals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Mice; Organophosphonates; Phosphoproteins; Protein Tyrosine Phosphatases; Steroids; Time Factors; Tumor Cells, Cultured | 2002 |
[Study of the inhibitory effect of PhAsO on gap junctional communication and its damages to cellular DNA of human skin fibroblast cells].
Topics: Arsenicals; Cell Communication; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Gap Junctions; Humans; Skin | 2002 |
NF-kappaB inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Arsenicals; Cell Hypoxia; Cysteine Endopeptidases; Down-Regulation; Lactams; Mice; Multienzyme Complexes; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Proteasome Endopeptidase Complex; Radiation Tolerance; Tumor Cells, Cultured | 2003 |
Phenylarsine oxide inhibits alpha-latrotoxin-stimulated [3H]GABA release from rat brain synaptosomes.
Topics: 4-Aminopyridine; Animals; Arsenicals; Brain; Carrier Proteins; Cell Membrane; Cytosol; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Rats; Rats, Wistar; Spider Venoms; Synaptosomes; Tritium | 2003 |
Reactive oxygen species are involved in arsenic trioxide inhibition of pyruvate dehydrogenase activity.
Topics: Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Chelating Agents; Copper Sulfate; Enzyme Inhibitors; Ferrous Compounds; HL-60 Cells; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Mitochondria, Heart; Myocardium; NADPH Oxidases; Oxides; Pyruvate Dehydrogenase Complex; Reactive Oxygen Species; Sulfhydryl Compounds; Swine | 2003 |
[Effect of inductors and inhibitors of the mitochondrial permeability transition pore on its opening and release of unidentified mitochondrial factor].
Topics: Animals; Arsenicals; Cyclosporine; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Proteins; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Rats; Rats, Wistar | 2003 |
Syntaxin 1A modulates the voltage-gated L-type calcium channel (Ca(v)1.2) in a cooperative manner.
Topics: Animals; Antigens, Surface; Arsenicals; Calcium; Calcium Channels, L-Type; Cell Membrane; Chelating Agents; Cysteine; Dimercaprol; Dimerization; Disulfides; Electric Conductivity; Female; Gene Expression; Membrane Potentials; Mutation; Nerve Tissue Proteins; Oocytes; Protein Conformation; Protein Structure, Secondary; Rabbits; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; Syntaxin 1; Transfection; Xenopus laevis | 2003 |
Thiol-modifying phenylarsine oxide inhibits guanine nucleotide binding of Rho but not of Rac GTPases.
Topics: Actins; Acute-Phase Proteins; Arsenicals; Caco-2 Cells; Cysteine; Cytoskeleton; Enzyme Inhibitors; Guanine Nucleotides; Humans; Protein Conformation; rac GTP-Binding Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; rhoC GTP-Binding Protein | 2003 |
Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons.
Topics: Analgesics, Opioid; Animals; Arsenicals; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; Ligands; Microscopy, Confocal; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Potassium; Receptors, Opioid, mu; Somatostatin; Sucrose; Time Factors | 2003 |
A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity.
Topics: Amino Acid Sequence; Animals; Arsenicals; Binding Sites; Capsaicin; Carrier Proteins; ErbB Receptors; Hot Temperature; Humans; Ion Channel Gating; Membrane Proteins; Molecular Sequence Data; Mutation; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Rats; Receptor, trkA; Receptors, Drug; Recombinant Fusion Proteins; Sequence Deletion; Type C Phospholipases; Xenopus | 2003 |
A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells.
Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Angiogenesis Inhibitors; Animals; Aorta; Apoptosis; Arsenicals; Biotin; Calcium; Cattle; Cell Division; Cell Survival; Chick Embryo; Cytosol; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Eosine Yellowish-(YS); Female; Immunohistochemistry; Ion Channels; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Chemical; Neovascularization, Pathologic; Peptides; Time Factors | 2003 |
IL-1 beta scavenging by the type II IL-1 decoy receptor in human neutrophils.
Topics: Arsenicals; Autoantigens; Cadaverine; Cell Line; Clathrin; Endocytosis; Endosomes; Humans; Interleukin-1; Iodine Radioisotopes; Ligands; Membrane Proteins; Neutrophils; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Sodium Azide; Time Factors; Vesicular Transport Proteins | 2003 |
Phenylarsine oxide and H2O2 plus vanadate induce reverse translocation of phorbol-ester-activated PKCbetaII.
Topics: Animals; Arsenicals; Cell Membrane; Cells, Cultured; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Hydrogen Peroxide; Neutrophils; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Transport; Protein Tyrosine Phosphatases; Sus scrofa; Tetradecanoylphorbol Acetate; Vanadates | 2003 |
Ligand internalization by cloned neuropeptide Y Y5 receptors excludes Y2 and Y4 receptor-selective peptides.
Topics: Animals; Arsenicals; Binding, Competitive; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Endosomes; Filipin; Humans; Kidney; Ligands; Neuropeptide Y; Pancreas; Receptors, Neuropeptide Y; Temperature | 2003 |
The curative power of 4-(2:6-diaminopyrimidin-4-ylamino) phenylarsine oxide (compound 12,065) in infections of Trypanosoma rhodesiense in laboratory animals.
Topics: Animals; Animals, Laboratory; Arsenicals; Humans; Mice; Rats; Trypanosoma brucei rhodesiense; Trypanosomiasis; Trypanosomiasis, African; Tsetse Flies | 1958 |
Activation of SRC tyrosine kinases in response to ICAM-1 ligation in pulmonary microvascular endothelial cells.
Topics: Allopurinol; Animals; Arsenicals; Chelating Agents; Cross-Linking Reagents; Cytoskeletal Proteins; Deferoxamine; Detergents; Dimethyl Sulfoxide; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Humans; Intercellular Adhesion Molecule-1; Intracellular Signaling Peptides and Proteins; Lung; Mice; Microcirculation; Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Phosphatase 2; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Recombinant Proteins; Signal Transduction; src-Family Kinases; Threonine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Xanthine Oxidase | 2003 |
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.
Topics: Adenine; Adenosine; Animals; Arsenicals; Benzamidines; Cell Death; Cell Division; Diminazene; Drug Resistance; Female; Gene Silencing; Hypoxanthine; Inhibitory Concentration 50; Inosine; Melarsoprol; Mice; Mutation; Nucleoside Transport Proteins; Pentamidine; Stilbamidines; Trypanosoma brucei brucei | 2003 |
Induction of apoptosis without redox catastrophe by thioredoxin-inhibitory compounds.
Topics: Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; Arsenicals; bcl-2 Homologous Antagonist-Killer Protein; Caspases; Diamide; Enzyme Inhibitors; HL-60 Cells; Humans; Membrane Proteins; Mitochondria; Oxidation-Reduction; Sulfhydryl Reagents; Thioredoxins | 2003 |
[Release of unidentified substances of mitochondrial origin--evidence of mitochondrial permeability transition pore opening in the heart mitochondria of rats ].
Topics: Animals; Arsenicals; Calcium Chloride; Cyclosporine; Ion Channel Gating; Ion Channels; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Mitochondrial Swelling; Oxidative Stress; Rats; Rats, Wistar | 2003 |
[Determination of the stable mitochondrial factor in vivo].
Topics: Animals; Arsenicals; Biomarkers; Coronary Circulation; Dogs; Hindlimb; Ion Channels; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Myocardial Contraction; Myocardial Reperfusion Injury; Oxidative Stress; Regional Blood Flow | 2003 |
Tyrosine phosphatase inhibition induces loss of blood-brain barrier integrity by matrix metalloproteinase-dependent and -independent pathways.
Topics: Animals; Arsenicals; Blood-Brain Barrier; Blotting, Western; Brain; Cell Communication; Cells, Cultured; Electric Impedance; Electrophoresis; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Immunohistochemistry; Matrix Metalloproteinases; Phosphorylation; Protein Tyrosine Phosphatases; Swine; Tight Junctions; Vanadates | 2004 |
Reduction and uptake of methylene blue by human erythrocytes.
Topics: Arsenicals; Ascorbic Acid; Cell Membrane; Dose-Response Relationship, Drug; Erythrocytes; Extracellular Fluid; Ferricyanides; Glutathione; Humans; Methylene Blue; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidative Stress; Subcellular Fractions | 2004 |
The effects of monobromobimane on neuronal cell death in the hippocampus after transient global cerebral ischemia in rats.
Topics: Animals; Arsenicals; Brain Ischemia; Bridged Bicyclo Compounds; Calcium Chloride; Caspase 3; Caspases; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Ischemic Attack, Transient; Male; Mitochondria; Mitochondrial Swelling; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion; Time Factors | 2004 |
The effects of monobromobimane on calcium and phenylarsineoxide-induced mitochondrial swelling and cytochrome C release in isolated brain mitochondria.
Topics: Animals; Arsenicals; Blotting, Western; Bridged Bicyclo Compounds; Calcium; Cytochromes c; Dose-Response Relationship, Drug; Hippocampus; In Situ Nick-End Labeling; In Vitro Techniques; Ischemic Attack, Transient; Male; Mitochondria; Mitochondrial Swelling; Models, Biological; Rats; Rats, Wistar; Sulfhydryl Reagents | 2004 |
Production of phenyllactic acid by lactic acid bacteria: an approach to the selection of strains contributing to food quality and preservation.
Topics: Arsenicals; Fermentation; Food Microbiology; Food Preservation; Lactates; Lactobacillus; Tyrosine | 2004 |
Increasing neutrophil F-actin corrects CD11b exposure in Type 2 diabetes.
Topics: Actins; Antigens, Surface; Arsenicals; CD11b Antigen; Cells, Cultured; Cytoskeleton; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Humans; Immunoblotting; Male; Middle Aged; Neutrophils; Phalloidine; Phosphotyrosine; Polymers | 2004 |
Redox modulation of basal and beta-adrenergically stimulated cardiac L-type Ca(2+) channel activity by phenylarsine oxide.
Topics: Animals; Arsenicals; Calcium; Calcium Channels, L-Type; Colforsin; Cyclic AMP; Dithiothreitol; Drug Evaluation, Preclinical; Electrophysiology; Guinea Pigs; Isoproterenol; Myocytes, Cardiac; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Adrenergic, beta; Signal Transduction; Thionucleotides; Time Factors | 2004 |
[Role of nitric oxide and mitochondrial permeability pore in changes of oxygen consumption in the working skeletal muscle].
Topics: Animals; Arsenicals; Dogs; Electric Stimulation; Ion Channels; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxygen Consumption; Regional Blood Flow | 2004 |
[Aging-related increase of sensitivity of the mitochondrial permeability transition pore to inductors in the rat heart].
Topics: Aging; Animals; Arsenicals; bcl-2-Associated X Protein; Calcium Chloride; Gene Expression; In Vitro Techniques; Ion Channels; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardium; Proto-Oncogene Proteins c-bcl-2; Rats | 2004 |
Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates | 2004 |
Mechanisms of arsenic-induced prolongation of cardiac repolarization.
Topics: Animals; Arsenic Trioxide; Arsenicals; Calcium; Electrophysiology; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Ventricles; Humans; Myocytes, Cardiac; Oxides; Potassium Channels | 2004 |
Tyrosine phosphorylation inhibits the interaction of 14-3-3 proteins with the plant plasma membrane H+-ATPase.
Topics: 14-3-3 Proteins; Arabidopsis; Arsenicals; Base Sequence; Cell Membrane; DNA, Plant; Enzyme Inhibitors; Mutagenesis, Site-Directed; Phosphorylation; Plant Proteins; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proton-Translocating ATPases; Receptor, IGF Type 1; Recombinant Proteins; Tyrosine; Tyrosine 3-Monooxygenase; Zea mays | 2004 |
Activation of second messenger-dependent protein kinases induces muscarinic acetylcholine receptor desensitization in rat thyroid epithelial cells.
Topics: Animals; Arsenicals; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Epithelial Cells; Indoles; Maleimides; Muscarinic Agonists; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Muscarinic; Second Messenger Systems; Sucrose; Tetradecanoylphorbol Acetate; Thyroid Gland | 2004 |
Phenylarsine oxide (PAO) more intensely induces apoptosis in acute promyelocytic leukemia and As2O3-resistant APL cell lines than As2O3 by activating the mitochondrial pathway.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Membrane Potentials; Mitochondria; Oxides; Proto-Oncogene Proteins c-bcl-2 | 2004 |
Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide.
Topics: Arsenicals; Cadmium; Doxorubicin; Gene Silencing; Glutaredoxins; HeLa Cells; Humans; Oxidative Stress; Oxidoreductases; RNA, Small Interfering | 2004 |
Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells.
Topics: Animals; Arsenicals; Cell Line; Cell Survival; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Phosphorylation; Rats; Time Factors; Tyrosine | 2005 |
Inhibition of sequestration of human B2 bradykinin receptor by phenylarsine oxide or sucrose allows determination of a receptor affinity shift and ligand dissociation in intact cells.
Topics: Arsenicals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cell Line; Dose-Response Relationship, Drug; Humans; Ligands; Protein Binding; Receptor, Bradykinin B2; Sucrose | 2004 |
Internalization and trafficking of the human and rat growth hormone-releasing hormone receptor.
Topics: Animals; Arsenicals; Caveolin 1; Caveolins; Cell Line; Cell Membrane; Cells, Cultured; Clathrin; Cricetinae; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Fluorescent Dyes; Growth Hormone-Releasing Hormone; Humans; Male; Membrane Microdomains; Pituitary Gland, Anterior; Protein Synthesis Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Transfection | 2005 |
Nitric oxide block of outward-rectifying K+ channels indicates direct control by protein nitrosylation in guard cells.
Topics: Arsenicals; Hydrogen-Ion Concentration; Ion Channel Gating; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Potassium Channels; Signal Transduction; Sulfhydryl Reagents; Vicia faba | 2004 |
Role of mitochondrial permeability transition pore in coated-platelet formation.
Topics: Adult; Apoptosis; Arsenicals; Atractyloside; Benzimidazoles; Blood Platelets; Bongkrekic Acid; Carbocyanines; Collagen; Crotalid Venoms; Cyclosporine; Cytoplasmic Granules; Diamide; Drug Synergism; Flow Cytometry; Fluorescent Dyes; Humans; Ion Channels; Lectins, C-Type; Membrane Lipids; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Phosphatidylserines; Platelet Activation; Thrombin; Thromboplastin; Ubiquinone | 2005 |
Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation.
Topics: Adaptation, Biological; Animals; Anisomycin; Arsenicals; Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL22; Chemokines, CC; Chlorocebus aethiops; COS Cells; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Fluorescent Antibody Technique; Growth Cones; In Vitro Techniques; Nerve Growth Factors; Netrin-1; Neurons; Neuropilin-1; Protein Synthesis Inhibitors; Retina; Semaphorin-3A; Statistics, Nonparametric; Time Factors; Transfection; Tumor Suppressor Proteins; Xenopus laevis | 2005 |
Tyrosine phosphates act on steroidogenesis through the activation of arachidonic acid release.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arsenicals; Blotting, Western; Cell Line; Coenzyme A Ligases; Enzyme Activation; Enzyme Inhibitors; Immune Sera; Male; Mice; Protein Tyrosine Phosphatases; Rabbits; Rats; Rats, Wistar; Recombinant Proteins; Steroids | 2004 |
[Sensitivity of phenylarsineoxide-induced mitochondrial permeability transition pore opening in the heart of old rats during intermittent hypoxic training].
Topics: Adaptation, Physiological; Aging; Animals; Arsenicals; Heart; Hypoxia; Ion Channels; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Oxidative Stress; Rats; Rats, Wistar | 2004 |
Reversible activation of secretory phospholipase A2 by sulfhydryl reagents.
Topics: Animals; Arsenicals; Calcium; Cysteine; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Glutathione; Group II Phospholipases A2; Humans; PC12 Cells; Phospholipases A; Phospholipases A2; Rats; Receptors, Cell Surface; Sulfhydryl Reagents; Thimerosal; Tumor Cells, Cultured | 2005 |
Identification by site-directed mutagenesis and chemical modification of three vicinal cysteine residues in rat mitochondrial carnitine/acylcarnitine transporter.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arsenicals; Carnitine; Carnitine Acyltransferases; Cattle; Cysteine; Diamide; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liposomes; Mitochondria; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenanthrolines; Rats; Recombinant Proteins; Sequence Homology, Amino Acid | 2005 |
Stimulation of intracellular Ca2+ elevation in neutrophils by thiol-oxidizing phenylarsine oxide.
Topics: Animals; Aorta, Abdominal; Aristolochic Acids; Arsenicals; Barium; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Carbamates; Cell Membrane; Enzyme Inhibitors; Furans; Indazoles; Indoles; Male; Manganese; NADPH Oxidases; Neutrophils; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Strontium; Sulfonamides | 2005 |
Phenylarsine oxide is able to dissipate synaptic vesicle acidic pool.
Topics: Animals; Arsenicals; Brain; Calcium Signaling; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Dithiothreitol; Enzyme Inhibitors; Exocytosis; gamma-Aminobutyric Acid; Glutamic Acid; Hydrogen-Ion Concentration; Ionophores; Male; Membrane Potentials; Mitochondria; Neurotransmitter Agents; Potassium Chloride; Rats; Rats, Wistar; Synaptic Transmission; Synaptic Vesicles; Synaptosomes | 2005 |
Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
Topics: Adenosine Diphosphate Ribose; Animals; Arsenicals; Blood Platelets; Calcium; Cations; Cell Membrane; Electric Conductivity; Megakaryocytes; Membrane Proteins; Mice; Mice, Inbred C57BL; Models, Animal; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction | 2005 |
Comparative kinetic analysis reveals that inducer-specific ion release precedes the mitochondrial permeability transition.
Topics: Alamethicin; Animals; Arsenicals; Biophysics; Calcium; Intracellular Membranes; Ion-Selective Electrodes; Iron; Kinetics; Mitochondria, Liver; Onium Compounds; Organophosphorus Compounds; Oxygen Consumption; Permeability; Rats; Rats, Inbred BN; Signal Processing, Computer-Assisted | 2005 |
Pathways for clearance of surfactant protein A from the lung.
Topics: Actins; Amantadine; Animals; Arsenicals; Cells, Cultured; Clathrin; Cytochalasin D; Dopamine Agents; Endocytosis; Enzyme Inhibitors; Macrophages, Alveolar; Male; Nucleic Acid Synthesis Inhibitors; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley | 2005 |
Dephosphorylation of the Rieske iron-sulfur protein after induction of the mitochondrial permeability transition.
Topics: Animals; Arsenicals; Calcium Chloride; Cyclosporine; Electron Transport Complex III; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Iron-Sulfur Proteins; Male; Mitochondria, Liver; Mitochondrial Membranes; Mitochondrial Swelling; Permeability; Phosphoprotein Phosphatases; Phosphorylation; Proteomics; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide | 2005 |
Methylene blue stimulates 2-deoxyglucose uptake in L929 fibroblast cells.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Arsenicals; beta-Cyclodextrins; Cytochalasin B; Deoxyglucose; Dose-Response Relationship, Drug; Ferricyanides; Fibroblasts; Glucose Transporter Type 1; Methylene Blue; Mice; Wortmannin | 2006 |
Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex.
Topics: Adaptor Proteins, Signal Transducing; Arsenicals; Cell Line; Diamide; Dimercaprol; Humans; Multiprotein Complexes; Oxidants; Oxidation-Reduction; Phosphorylation; Protein Kinases; Proteins; Recombinant Proteins; Regulatory-Associated Protein of mTOR; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Small Interfering; Signal Transduction; TOR Serine-Threonine Kinases; Transfection | 2005 |
Evidence of a role for tyrosine dephosphorylation in the control of postgermination arrest of development by abscisic acid in Arabidopsis thaliana L.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Arsenicals; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Germination; MAP Kinase Signaling System; Phosphorylation; Protein Tyrosine Phosphatases; rab GTP-Binding Proteins; Tyrosine | 2006 |
Internalization of cloned pancreatic polypeptide receptors is accelerated by all types of Y4 agonists.
Topics: Adenylyl Cyclases; Animals; Arsenicals; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Female; Humans; Peptides; Peptides, Cyclic; Rats; Receptors, Neuropeptide Y | 2005 |
The role of endocytosis in renal dopamine D1 receptor signaling.
Topics: Animals; Arsenicals; Cell Line; Cyclic AMP; Dopamine; Isoproterenol; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Signal Transduction; Swine | 2006 |
Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox.
Topics: Acetophenones; Animals; Arsenicals; Blotting, Northern; Blotting, Western; Cell Nucleus; Cell Proliferation; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Membrane Transport Proteins; Microcirculation; NADP; NADPH Oxidases; Nitric Oxide; Oligonucleotides, Antisense; Onium Compounds; Oxidative Stress; Oxygen; Phosphoproteins; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Thymidine; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
[Determination of phenylarsenic compounds in environmental samples by high performance liquid chromatography].
Topics: Arsenicals; Chromatography, High Pressure Liquid; Molecular Structure; Reproducibility of Results | 2005 |
Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.
Topics: Alkaline Phosphatase; Arsenicals; Cell Line; Chlorpromazine; Clathrin; Endocytosis; Fluorescein-5-isothiocyanate; Humans; Indomethacin; Keratins; Kinetics; Microscopy, Confocal; Nystatin; Respiratory Mucosa; RNA, Messenger; Serum Albumin, Bovine; Thermodynamics | 2006 |
Membrane-associated STAT3 and PY-STAT3 in the cytoplasm.
Topics: Adaptor Proteins, Vesicular Transport; Antigens; Arsenicals; Blotting, Western; Cell Line; Cell Membrane; Clathrin; Clathrin Light Chains; Cross-Linking Reagents; Cytoplasm; Cytosol; Detergents; DNA; Dynamins; Endocytosis; Endosomes; Humans; Interleukin-6; Luciferases; Microscopy, Electron; Microscopy, Fluorescence; Nerve Tissue Proteins; Signal Transduction; STAT3 Transcription Factor; Subcellular Fractions; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 2006 |
Jab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1.
Topics: Animals; Arsenicals; Astrocytes; Blotting, Western; Brain; Cell Line; Cells, Cultured; COP9 Signalosome Complex; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Gene Library; Genes, Reporter; Glutathione Transferase; Humans; Immunoprecipitation; Insecta; Intracellular Signaling Peptides and Proteins; Microscopy, Fluorescence; Models, Biological; Peptide Hydrolases; Plasmids; Protein Binding; Protein Structure, Tertiary; Receptor, PAR-2; RNA, Small Interfering; Signal Transduction; Time Factors; Transcription Factor AP-1; Transfection; Trypsin; Two-Hybrid System Techniques | 2006 |
Osmotic effects on vacuolar ion release in guard cells.
Topics: Abscisic Acid; Aquaporins; Arsenicals; Biological Transport; Calcium; Carbohydrate Metabolism; Commelina; Cytoplasm; Ion Channels; Ions; Kinetics; Models, Biological; Osmosis; Osmotic Pressure; Plant Physiological Phenomena; Plants; Pressure; Shock; Signal Transduction; Time Factors; Vacuoles | 2006 |
AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arsenicals; Cells, Cultured; Colchicine; Colforsin; Cyclic AMP; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Kidney Tubules, Proximal; Losartan; Microtubules; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sucrose | 2006 |
Lipopolysaccharide transiently activates THP-1 cell adhesion.
Topics: Arsenicals; CD18 Antigens; Cell Adhesion; Cell Line; Enzyme Inhibitors; Fibrinogen; Fibronectins; Humans; Lipopolysaccharides; Monocytes; Protein Tyrosine Phosphatases; Signal Transduction | 2006 |
Role of vicinal protein thiols in radiation and cytotoxic responses.
Topics: Animals; Arsenicals; Cell Line; Cell Survival; Cricetinae; Dithiothreitol; Glutathione; Mercaptoethanol; Molecular Structure; Oxidation-Reduction; Oxygen; Proteins; Radiation Tolerance; Sulfhydryl Compounds | 2006 |
Effect of PAO (phenylarsine oxide) on the inhibitory effect of insulin and IGF-1 on insulin release from INS-1 cells.
Topics: Animals; Arsenicals; Blotting, Western; Cell Line; Cell Membrane; Dimercaprol; Drug Interactions; Feedback, Physiological; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 2; Insulin; Insulin Secretion; Insulin-Like Growth Factor I; Mice; Mice, Knockout; Radioimmunoassay; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction | 2006 |
Bovine factor B: cloning, expression, and characterization.
Topics: Animals; Arsenicals; Base Sequence; Cadmium; Calcium; Cattle; Cloning, Molecular; Complement Factor B; Cysteine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Mitochondrial Proton-Translocating ATPases; Molecular Sequence Data; Proton-Translocating ATPases; Recombinant Proteins; Toluene; Zinc | 2006 |
CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake.
Topics: alpha-Crystallin B Chain; Animals; Arsenicals; Calcium; Calcium Signaling; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Intracellular Membranes; Mice; Mitochondria, Heart; Myocytes, Cardiac; Nitric Oxide; Ouabain; Permeability; Rhodamines; Time Factors | 2006 |
Homologous down-regulation of histamine H3 receptors in rat striatal slices.
Topics: Animals; Arsenicals; Binding, Competitive; Colforsin; Corpus Striatum; Cyclic AMP; Down-Regulation; Endocytosis; Enzyme Inhibitors; Histamine; Histamine Agonists; Imidazoles; Male; Organ Culture Techniques; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptor Aggregation; Receptors, Histamine H3 | 2006 |
Luminal oxidants selectively modulate electrogenic ion transport in rat colon.
Topics: Animals; Arsenicals; Atropine; Calcium; Cell Membrane Permeability; Chloramines; Chlorides; Colon; Electrophysiology; Hydrogen Peroxide; Indomethacin; Ion Transport; Male; Oxidants; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tosyl Compounds; Water | 2006 |
The dynamics of recycled acetylcholine receptors at the neuromuscular junction in vivo.
Topics: Animals; Arsenicals; Female; Mice; Microscopy, Confocal; Neuromuscular Junction; Protein Transport; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Synapses; Vanadates | 2006 |
Phenylarsine oxide inhibited beta-adrenergic receptor-mediated IL-6 secretion: inhibition of cAMP accumulation and CREB activation in cardiac fibroblasts.
Topics: Animals; Arsenicals; Cells, Cultured; CREB-Binding Protein; Cyclic AMP; Dose-Response Relationship, Drug; Fibroblasts; Interleukin-6; Mice; Mice, Inbred BALB C; Myocardium; Receptors, Adrenergic, beta | 2007 |
Protein disulfide-isomerase mediates delivery of nitric oxide redox derivatives into platelets.
Topics: Amino Acid Transport System L; Arsenicals; Bacitracin; Biological Transport; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Glutathione Peroxidase; Guanylate Cyclase; Humans; Nitric Oxide; Oxidation-Reduction; Protein Disulfide-Isomerases; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2007 |
[Effects of changes in mitochondrial permeability transition of medullary neurons on arterial pressure in rats].
Topics: Animals; Arsenicals; Blood Pressure; Dose-Response Relationship, Drug; Medulla Oblongata; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats | 2006 |
Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505.
Topics: Arsenicals; Camptothecin; Cysteine; DNA Cleavage; DNA Topoisomerases, Type I; Enzyme Inhibitors; Ethylmaleimide; Humans; Mutagenesis, Site-Directed; Protein Conformation; Sulfhydryl Compounds; Topoisomerase I Inhibitors | 2007 |
Reversible protein tyrosine phosphorylation affects pollen germination and pollen tube growth via the actin cytoskeleton.
Topics: Actins; Arsenicals; Cell Differentiation; Cell Polarity; Cytoskeleton; Enzyme Inhibitors; Genistein; Germination; Lilium; Phosphorylation; Pollen; Pollen Tube; Protein Tyrosine Phosphatases; Protoplasts; Tyrosine | 2007 |
NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemoreceptor sensitivity in heart failure rabbits.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arsenicals; Blotting, Western; Carotid Body; Chemoreceptor Cells; Cyclic N-Oxides; Heart Failure; Male; Models, Animal; NADPH Oxidases; Rabbits; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spin Labels; Superoxides | 2007 |
Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Arsenicals; Biphenyl Compounds; Blotting, Western; Caspase 3; DNA Fragmentation; Flow Cytometry; Fluorescent Antibody Technique; Imidazoles; Irbesartan; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Tetrazoles; Transfection | 2007 |
Quantitative evaluation of the binding of phenylarsenic species to glutathione, isotocin, and thioredoxin by means of electrospray ionization time-of-flight mass spectrometry.
Topics: Arsenicals; Glutathione; Oxytocin; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Thioredoxins | 2007 |
Oxidative inhibition of protein phosphatase 2A activity: role of catalytic subunit disulfides.
Topics: Animals; Arsenicals; Cerebral Cortex; Cross-Linking Reagents; Disulfides; Oxidation-Reduction; Phosphines; Phosphoric Monoester Hydrolases; Protein Phosphatase 2; Protein Subunits; Rats; Reducing Agents; Sulfhydryl Compounds | 2007 |
Subcellular localization of sigma-2 receptors in breast cancer cells using two-photon and confocal microscopy.
Topics: Arsenicals; Breast Neoplasms; Caspases; Endocytosis; Endoplasmic Reticulum; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Ligands; Microscopy, Confocal; Models, Chemical; Photons; Receptors, sigma | 2007 |
[Inhibition of mitochondrial permeability transition pore is one of the mechanisms of cardioprotective effect of coenzyme Q10].
Topics: Animals; Arsenicals; Cardiotonic Agents; Coenzymes; Guinea Pigs; In Vitro Techniques; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardial Reperfusion Injury; Oxygen Consumption; Ubiquinone | 2007 |
Na+/H+ exchanger inhibitor cariporide attenuates the mitochondrial Ca2+ overload and PTP opening.
Topics: Animals; Anti-Arrhythmia Agents; Arsenicals; Calcium; Cardiotonic Agents; Decanoic Acids; Glyburide; Guanidines; Heart Ventricles; Hydroxy Acids; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocytes, Cardiac; Ouabain; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Time Factors | 2007 |
On the opening of an insensitive cyclosporin A non-specific pore by phenylarsine plus mersalyl.
Topics: Animals; Arsenicals; Calcium; Cross-Linking Reagents; Cyclosporine; Ethylmaleimide; Ion Channel Gating; Membrane Potential, Mitochondrial; Mersalyl; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Mitochondrial Membranes; Mitochondrial Swelling; Permeability; Porins; Protein Binding; Rats; Sulfhydryl Compounds; Sulfhydryl Reagents | 2007 |
Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB5 toxin that targets the endoplasmic reticulum chaperone BiP.
Topics: Animals; Arsenicals; Chlorocebus aethiops; Clathrin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Escherichia coli Proteins; Golgi Apparatus; Heat-Shock Proteins; HeLa Cells; Humans; Microscopy, Fluorescence; Molecular Chaperones; Shiga-Toxigenic Escherichia coli; Subtilisins; Vero Cells | 2008 |
Experimental studies on the mode of action of phenylarsenoxides.
Topics: Arsenicals | 1949 |
Mitochondrial recycling of ascorbic acid as a mechanism for regenerating cellular ascorbate.
Topics: alpha-Tocopherol; Animals; Arsenicals; Ascorbic Acid; Carmustine; Dehydroascorbic Acid; Diamide; Ethylmaleimide; Ferricyanides; Guinea Pigs; In Vitro Techniques; Maleates; Mitochondria, Muscle; Oxidation-Reduction; Sulfhydryl Reagents | 2007 |
Two independent forms of endocytosis maintain embryonic cell surface homeostasis during early development.
Topics: Agatoxins; Animals; Arsenicals; Cell Division; Cell Membrane; Embryo, Nonmammalian; Embryonic Development; Endocytosis; Endosomes; Exocytosis; Fluorescent Dyes; Homeostasis; Microinjections; Ovum; Pyridinium Compounds; Quaternary Ammonium Compounds; RNA, Messenger; Spider Venoms; src-Family Kinases; Strongylocentrotus purpuratus; Tetradecanoylphorbol Acetate | 2008 |
Phosphatidylinositol kinases as regulators of GA-stimulated alpha-amylase secretion in barley (Hordeum vulgare).
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine; alpha-Amylases; Androstadienes; Arsenicals; Chromones; Dimercaprol; Gibberellins; Hordeum; Morpholines; Phosphatidylinositol 3-Kinases; Protoplasts; Vacuoles; Wortmannin | 2008 |
Regulation of CA(v)3.2 Ca2+ channel activity by protein tyrosine phosphorylation.
Topics: Animals; Arsenicals; Calcium Channels, T-Type; Electrophysiology; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Oocytes; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tyrosine; Xenopus; Xenopus Proteins | 2008 |
[The modulation of mitochondrial pore sensitivity of isolated myocardial preparations to the action of phenylarsenoxide].
Topics: Adaptation, Physiological; Aging; Animals; Arsenicals; Carotid Artery, Common; Electric Stimulation; Guinea Pigs; Hypoxia; In Vitro Techniques; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle Contraction; Myocardial Contraction; Myocardium; Nitric Oxide; Nitroprusside | 2007 |
Reactive oxygen species generated by thiol-modifying phenylarsine oxide stimulate the expression of protein L-isoaspartyl methyltransferase.
Topics: Arsenicals; Cell Line, Tumor; Cysteine; Down-Regulation; Enzyme Inhibitors; Humans; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Reactive Oxygen Species; RNA, Small Interfering; Up-Regulation | 2008 |
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators.
Topics: Animals; Arsenicals; Calcium Channels; CHO Cells; Cricetinae; Cricetulus; Data Interpretation, Statistical; Electrophysiology; Estrenes; Mustard Plant; NADPH Oxidases; Neomycin; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Plant Oils; Protein Synthesis Inhibitors; Pyrrolidinones; Solutions; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2008 |
The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition.
Topics: Animals; Arsenicals; Benzoquinones; Cell Membrane Permeability; Cyclophilins; Cyclosporine; Dibenzocycloheptenes; Enzyme Inhibitors; Ethylmaleimide; Ion Transport; Mitochondria, Heart; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Mitochondrial Membranes; Mitochondrial Proteins; Peptidyl-Prolyl Isomerase F; Phosphate Transport Proteins; Protein Binding; Protein Conformation; Rats; Spiro Compounds | 2008 |
[Mitochondrial permeability transition pore opening inhibition by ecdysterone in heart mitochondria of aging rats].
Topics: Aging; Animals; Arsenicals; Calcium; Cyclosporine; Ecdysterone; Free Radical Scavengers; Ion Channel Gating; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxides | 2008 |
[In vivo effect of precursors of ubiquinone biosynthesis on sensitivity of mitochondrial permeability transition pore in the heart of old rats].
Topics: Aging; Animals; Arsenicals; Calcium; Male; Methionine; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardium; Parabens; Rats; Rats, Wistar; Ubiquinone; Vitamin E | 2008 |
Novel mechanism for suppression of hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by receptor-like tyrosine phosphatase-alpha.
Topics: Animals; Arsenicals; Cell Line; DNA, Complementary; Gene Expression Regulation; Glycosylation; Humans; Mice; Microscopy, Confocal; Models, Biological; Neurons; Phosphorylation; Rats; Receptor Protein-Tyrosine Kinases; Vanadates | 2008 |
An Experimental Test About the Mode Of Action Of Phenylarsoxides.
Topics: Arsenicals; Humans | 1948 |
Low-affinity transport of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.
Topics: 2,4-Dinitrophenol; Animals; Arsenicals; Biological Transport; Caveolae; Cell Line; Chlorpromazine; Clathrin; Deoxyglucose; Endocytosis; Epithelial Cells; Fluorescein-5-isothiocyanate; Lysosomes; Macrolides; Microscopy, Confocal; Pulmonary Alveoli; Rats; Serum Albumin; Sodium Azide | 2008 |
Thiol dependent isomerization of bovine albumin.
Topics: Arsenicals; Chromatography, Ion Exchange; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fluorescence; Isomerism; Serum Albumin, Bovine; Sulfhydryl Compounds | 2009 |
Reaction of the catalytic cysteine of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa with arsenite-BAL and phenylarsine oxide.
Topics: Arsenicals; Arsenites; Betaine-Aldehyde Dehydrogenase; Biocatalysis; Cysteine; Dimercaprol; Kinetics; Models, Molecular; Protein Conformation; Pseudomonas aeruginosa; Recombinant Proteins | 2009 |
Mitochondrial free [Ca2+] levels and the permeability transition.
Topics: Aequorin; Animals; Arsenicals; Buffers; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Cells, Cultured; Chromaffin Cells; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mutant Proteins; Perfusion; Permeability; Phosphates | 2009 |
Regulation of fast skeletal muscle activity by SERCA1 vicinal-cysteines.
Topics: Animals; Arsenicals; Calcium; Cysteine; Enzyme Inhibitors; Muscle Contraction; Muscle Fatigue; Oxidation-Reduction; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Up-Regulation | 2009 |
Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1.
Topics: Animals; Arsenicals; Cloning, Molecular; Codon, Terminator; Cysteine; Enzyme Activation; Escherichia coli; Mutagenesis, Site-Directed; Protein Multimerization; Rats; Recombinant Proteins; Selenium; Sepharose; Substrate Specificity; Thioredoxin Reductase 1 | 2009 |
Modulation of bovine sperm signalling pathways: correlation between intracellular parameters and sperm capacitation and acrosome exocytosis.
Topics: 1-Methyl-3-isobutylxanthine; Acrosome Reaction; Animals; Arsenicals; Calcium; Cattle; Cell Survival; Chlortetracycline; Cyclic AMP; Exocytosis; Heparin; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Phosphodiesterase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Reproductive Techniques; Signal Transduction; Sperm Capacitation; Spermatozoa; Time Factors; Vanadates | 2009 |
Cryopreservation affects bovine sperm intracellular parameters associated with capacitation and acrosome exocytosis.
Topics: 1-Methyl-3-isobutylxanthine; Acrosome Reaction; Animals; Arsenicals; Calcium; Cattle; Cell Survival; Chlortetracycline; Cryopreservation; Cyclic AMP; Exocytosis; Heparin; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Phosphodiesterase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Reproductive Techniques; Semen Preservation; Signal Transduction; Sperm Capacitation; Sperm Motility; Spermatozoa; Time Factors; Vanadates | 2009 |
A method for site-specific labeling of multiple protein thiols.
Topics: Affinity Labels; Arsenicals; Cysteine; Escherichia coli; Fluorescent Dyes; Maleimides; Periplasmic Binding Proteins; Protein Engineering; Proteins; Salmonella typhimurium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 2009 |
Further investigation into the mechanism of tachykinin NK(2) receptor-triggered serotonin release from guinea-pig proximal colon.
Topics: Animals; Arsenicals; Botulinum Toxins; Calcium Channel Blockers; Clorgyline; Colon; Exocytosis; Guinea Pigs; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicardipine; Oxidants; Oxidation-Reduction; Protein Tyrosine Phosphatases; Qa-SNARE Proteins; Receptors, Neurokinin-2; Serotonin | 2009 |
Phenylarsine oxide interferes with the death inducing signaling complex and inhibits tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis.
Topics: Apoptosis; Arsenicals; Burkitt Lymphoma; Caspase Inhibitors; Caspases; Cell Line, Tumor; Endocytosis; Enzyme Inhibitors; Humans; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2009 |
Dual action of phenylarsine oxide on the glucose transport activity of GLUT1.
Topics: Animals; Arsenicals; Biological Transport; Cell Line; Cytochalasin B; Enzyme Inhibitors; Fibroblasts; Glucose; Glucose Transporter Type 1; Mice; Succimer | 2009 |
Osmopriming-regulated changes of plasma membrane composition and function were inhibited by phenylarsine oxide in soybean seeds.
Topics: Arsenicals; Cell Membrane; Enzyme Inhibitors; Fatty Acids; Glycine max; Protein Tyrosine Phosphatases; Seeds | 2009 |
An improved phenylarsine oxide-affinity method identifies triose phosphate isomerase as a candidate redox receptor protein.
Topics: Albumins; Alkylation; Animals; Arsenicals; Brain Chemistry; Chromatography, Affinity; Nerve Tissue Proteins; Oxidation-Reduction; Phosphines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds; Triose-Phosphate Isomerase | 2010 |
NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Arsenicals; Blotting, Northern; Cell Line; Conserved Sequence; Cullin Proteins; Cysteine; Cytoskeletal Proteins; Enzyme Inhibitors; Kelch-Like ECH-Associated Protein 1; Mice; Mutagenesis, Site-Directed; NF-E2-Related Factor 2; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Binding; Transcriptional Activation; Ubiquitination | 2009 |
Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Arsenicals; Blotting, Northern; Cell Line, Tumor; Chlorides; Chlorocebus aethiops; Cloning, Molecular; Conserved Sequence; COS Cells; Cysteine; Cytoskeletal Proteins; Immunoblotting; Kelch-Like ECH-Associated Protein 1; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-E2-Related Factor 2; Plasmids; Protein Binding; Protein Stability; Signal Transduction; Transfection; Ubiquitination | 2010 |
Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.
Topics: Animals; Arsenicals; BH3 Interacting Domain Death Agonist Protein; Cell Death; Cell Line, Tumor; Complement Membrane Attack Complex; Cytotoxicity, Immunologic; Enzyme Activation; Fibroblasts; Gene Silencing; Humans; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Phosphoprotein Phosphatases; RNA, Small Interfering; Tyrosine | 2009 |
Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate.
Topics: Animals; Arsenicals; Chorda Tympani Nerve; Chromatography, Thin Layer; Diterpenes; DNA Primers; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Epithelium; Guanidines; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylinositol 4,5-Diphosphate; Quinine; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sweetening Agents; Taste; Taste Buds; TRPV Cation Channels | 2010 |
Calpain-dependent cleavage of SHP-1 and SHP-2 is involved in the dephosphorylation of Jurkat T cells induced by Entamoeba histolytica.
Topics: Arsenicals; Calpain; Cell Death; Dipeptides; Entamoeba histolytica; Enzyme Inhibitors; Humans; Jurkat Cells; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; T-Lymphocytes | 2010 |
Enhanced IL-12p40 production by phenylarsine oxide is mediated by cAMP response element in macrophages.
Topics: Animals; Arsenicals; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Female; Gene Expression Regulation; Interleukin-12 Subunit p40; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Response Elements; Signal Transduction | 2010 |
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
Topics: Animals; Arsenic Trioxide; Arsenicals; Arsenites; Cerebellar Neoplasms; Dose-Response Relationship, Drug; Hedgehog Proteins; Kruppel-Like Transcription Factors; Luciferases; Luminescent Proteins; Medulloblastoma; Mice; Mice, Knockout; Mice, Nude; Neoplasms, Experimental; NIH 3T3 Cells; Oxides; Protein Stability; Recombinant Fusion Proteins; Signal Transduction; Sodium Compounds; Transfection; Transplantation, Homologous; Tumor Suppressor Protein p53; Zinc Finger Protein Gli2 | 2010 |
Some critical aspects in the determination of binding constants by electrospray ionisation mass spectrometry at the example of arsenic bindings to sulphur-containing biomolecules.
Topics: Arsenic; Arsenicals; Chromatography, Gel; Glutathione; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Signal Processing, Computer-Assisted; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds | 2010 |
Arsenic-induced protein phosphorylation changes in HeLa cells.
Topics: Amino Acid Sequence; Arsenicals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mass Spectrometry; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Proteins | 2010 |
Indolyl-3-butyric acid-induced Arabidopsis stomatal opening mediated by 3',5'-cyclic guanosine-monophosphate.
Topics: Arabidopsis; Arsenicals; Calcium; Cyclic GMP; Guanylate Cyclase; Indoleacetic Acids; Indoles; Mutation; Plant Stomata; Second Messenger Systems; Signal Transduction | 2010 |
Phenylarsine oxide binding reveals redox-active and potential regulatory vicinal thiols on the catalytic subunit of protein phosphatase 2A.
Topics: Animals; Arsenicals; Brain; Disulfides; Dithiothreitol; Enzyme Inhibitors; Oxidation-Reduction; Protein Binding; Protein Phosphatase 2; Protein Subunits; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2011 |
Optimization of peptide and protein separation with a monolithic reversed-phase column and application to arsenic-binding studies.
Topics: Acetonitriles; Arsenic; Arsenicals; Chromatography, Reverse-Phase; Isoelectric Point; Linear Models; Peptides; Proteins; Sensitivity and Specificity; Sulfur; Trichloroacetic Acid; Vasopressins; Vasotocin | 2011 |
The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways.
Topics: Animals; Arsenicals; Binding Sites; Bridged Bicyclo Compounds; Cell Line; Cross-Linking Reagents; Cyclopentanes; Cysteine; Enzyme Inhibitors; Humans; Prostaglandins; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); ras Proteins; Signal Transduction; Transfection | 2011 |
Internalization of Sambucus nigra agglutinins I and II in insect midgut CF-203 cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Arsenicals; Caveolae; Cell Line; Chlorpromazine; Clathrin; Cytochalasin D; Digestive System; Endocytosis; Filipin; Fluorescein-5-isothiocyanate; Insecta; Macrolides; Microscopy, Confocal; Nystatin; Plant Lectins; Ribosome Inactivating Proteins; Wortmannin | 2011 |
Inhibition of β-amyloid1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons.
Topics: Amyloid beta-Peptides; Animals; Arsenicals; Cathepsin D; Cell Culture Techniques; Cell Survival; Cerebral Cortex; Dose-Response Relationship, Drug; Endocytosis; Endosomes; Lysosomes; Nerve Degeneration; Neurons; Peptide Fragments; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; rab7 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sucrose | 2011 |
Cysteine-3 and cysteine-4 are essential for the thioredoxin-like oxidoreductase and antioxidant activities of Plasmodium falciparum macrophage migration inhibitory factor.
Topics: Animals; Arsenicals; Computational Biology; Cysteine; DNA Damage; Enzyme Activation; Erythrocytes; Macrophage Migration-Inhibitory Factors; Malaria; Mutagenesis, Site-Directed; Mutation; Oxidative Stress; Oxidoreductases; Plasmodium falciparum; Protozoan Proteins; Rabbits; Stereoisomerism; Thioredoxins | 2011 |
Intracellular angiotensin II activates rat myometrium.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arsenicals; Autophagy; Brefeldin A; Calcium Signaling; Carbolines; Cells, Cultured; Egtazic Acid; Endocytosis; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Estrenes; Female; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Lysosomes; Macrocyclic Compounds; Macrolides; Models, Biological; Myometrium; NADP; Oxazoles; Piperazines; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ryanodine; Saralasin; Signal Transduction; Sirolimus; Type C Phospholipases; Uterus | 2011 |
Vicinal thiols are required for activation of the αIIbβ3 platelet integrin.
Topics: Arsenicals; Blood Platelets; Cells, Cultured; Humans; Integrin alpha2; Integrin beta3; Membrane Proteins; Oxidation-Reduction; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Sulfhydryl Compounds | 2011 |
Megalin/cubilin-mediated uptake of FITC-labeled IgG by OK kidney epithelial cells.
Topics: Animals; Arsenicals; beta-Cyclodextrins; Cattle; Cell Line; Chlorpromazine; Clathrin; Endocytosis; Epithelial Cells; Fluorescein-5-isothiocyanate; gamma-Globulins; Histocompatibility Antigens Class I; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Kidney; Ligands; Low Density Lipoprotein Receptor-Related Protein-2; Microscopy, Confocal; Opossums; Receptors, Cell Surface; Receptors, Fc | 2011 |
Highly selective fluorescent probe for vicinal-dithiol-containing proteins and in situ imaging in living cells.
Topics: Arsenic; Arsenicals; Cell Line; Fluorescent Dyes; Humans; Mitochondrial Proteins; Models, Molecular; Molecular Imaging; Molecular Structure; Naphthalimides; Staining and Labeling; Thioredoxins | 2011 |
SNAP-25 contains non-acylated thiol pairs that can form intrachain disulfide bonds: possible sites for redox modulation of neurotransmission.
Topics: Acylation; Animals; Arsenicals; Disulfides; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Solubility; Subcellular Fractions; Sulfhydryl Compounds; Synaptic Transmission; Synaptosomal-Associated Protein 25 | 2012 |
C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arsenicals; Cell Membrane; Chickens; Cysteine; HEK293 Cells; Humans; Hydrogen Peroxide; Molecular Sequence Data; Mutation; Nociception; Oxidation-Reduction; Peptide Fragments; Protein Multimerization; Protein Structure, Quaternary; Protein Subunits; Rats; Signal Transduction; Sulfhydryl Compounds; TRPV Cation Channels | 2011 |
Phenylarsine oxide induces apoptosis in Bax- and Bak-deficient cells through upregulation of Bim.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Arsenicals; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Blotting, Western; Cells, Cultured; Colorectal Neoplasms; Embryo, Mammalian; Fibroblasts; Humans; Immunoenzyme Techniques; Immunoprecipitation; Membrane Proteins; Mice; Mice, Knockout; Mice, Nude; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2012 |
Hydroxyethyl disulfide as an efficient metabolic assay for cell viability in vitro.
Topics: Acetaminophen; Arsenicals; Arsenites; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Disulfides; Ethanol; Etoposide; Humans; Hydrogen Peroxide; Hypoxia; Radiation, Ionizing; Toxicity Tests | 2012 |
Purification and characterization of ZmRIP1, a novel reductant-inhibited protein tyrosine phosphatase from maize.
Topics: Amino Acid Sequence; Arabidopsis; Arsenicals; Cell Nucleus; Chloroplasts; Cloning, Molecular; Cysteine; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutathione Transferase; Molecular Sequence Data; Oxidation-Reduction; Plant Proteins; Plants, Genetically Modified; Point Mutation; Protein Transport; Protein Tyrosine Phosphatases; Protoplasts; Signal Transduction; Zea mays | 2012 |
Surface masking shapes the traffic of the neuropeptide Y Y2 receptor.
Topics: Amino Acid Sequence; Animals; Arsenicals; Binding Sites; Cell Adhesion; Chelating Agents; CHO Cells; Cricetinae; Digitonin; Edetic Acid; Filipin; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; HEK293 Cells; Humans; Molecular Sequence Data; Peptide YY; Pertussis Toxin; Protein Binding; Protein Interaction Domains and Motifs; Protein Transport; Receptors, Neuropeptide Y; Surface-Active Agents | 2012 |
Qualitative and quantitative characterization of the arsenic-binding behaviour of sulfur-containing peptides and proteins by the coupling of reversed phase liquid chromatography to electrospray ionization mass spectrometry.
Topics: Animals; Arsenicals; Cattle; Chromatography, Reverse-Phase; Cysteine; Disulfides; Kinetics; Peptides; Protein Binding; Protein Folding; Proteins; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2012 |
Differential regulation of GLUT1 activity in human corneal limbal epithelial cells and fibroblasts.
Topics: Acrolein; Animals; Arsenicals; Berberine; Biological Transport; Cell Line; Disulfides; Epithelial Cells; Fibroblasts; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; Humans; Kinetics; Limbus Corneae; Mice; Nitrogen Oxides; Organ Specificity; Sodium Azide | 2013 |
Sirtuin-4 modulates sensitivity to induction of the mitochondrial permeability transition pore.
Topics: Arsenicals; Calcium; Cell Survival; Cross-Linking Reagents; Doxorubicin; Glutamate Dehydrogenase; Glutathione; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; RNA Interference; Sirtuins; Time Factors; Time-Lapse Imaging; Transfection; Tumor Necrosis Factor-alpha | 2013 |
Hydroxylamine acutely activates glucose uptake in L929 fibroblast cells.
Topics: Acrolein; Animals; Arsenicals; Azides; Biological Transport; Cell Line; Dose-Response Relationship, Drug; Fibroblasts; Glucose; Glucose Transporter Type 1; Hydroxylamine; Iodoacetamide; Mice; Time Factors | 2013 |
Inhibitors of PI(4,5)P2 synthesis reveal dynamic regulation of IgE receptor signaling by phosphoinositides in RBL mast cells.
Topics: Animals; Arsenicals; Cell Line, Tumor; Mast Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Quercetin; Rats; Receptors, IgE; Signal Transduction | 2013 |
Alkaline pH activates the transport activity of GLUT1 in L929 fibroblast cells.
Topics: Acrolein; Animals; Arsenicals; Berberine; Biological Transport; Cell Line; Cystine; Deoxyglucose; Enzyme Activators; Fibroblasts; Glucose Transporter Type 1; Humans; Hydrogen-Ion Concentration; Kinetics; Methylene Blue; Mice; Reducing Agents | 2014 |
Identification of CalDAG-GEFI as an intracellular target for the vicinal dithiol binding agent phenylarsine oxide in human platelets.
Topics: Arsenicals; Blood Platelets; Diamide; Dimercaprol; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Molecular Targeted Therapy; Oxidation-Reduction; Platelet Aggregation; Protein Binding; rap1 GTP-Binding Proteins; Thrombin; Thrombosis; Toluene | 2014 |
Histone H2B monoubiquitination is involved in regulating the dynamics of microtubules during the defense response to Verticillium dahliae toxins in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Arsenicals; Gene Expression Regulation, Plant; Genistein; Histones; Microtubules; Mycotoxins; Phosphorylation; Phosphotyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Verticillium | 2014 |
Endocytic mechanisms of graphene oxide nanosheets in osteoblasts, hepatocytes and macrophages.
Topics: Amiloride; Animals; Arsenicals; Cells, Cultured; Cytochalasin B; Cytochalasin D; Endocytosis; Fluorescein-5-isothiocyanate; Genistein; Graphite; Hepatocytes; Humans; Macrophages; Mice; Nanoparticles; Osteoblasts; Oxides; Polyethylene Glycols | 2014 |
Presence of ecto-protein tyrosine phosphatase activity is vital for survival of Setaria cervi, a bovine filarial parasite.
Topics: Animals; Arsenicals; Aspirin; Catalytic Domain; Cattle; Cattle Diseases; Chalcone; Diethylcarbamazine; Enzyme Inhibitors; Female; Filaricides; Host-Parasite Interactions; Microfilariae; Protein Tyrosine Phosphatases; Setaria Nematode; Setariasis; Vanadates | 2014 |
Characterization of ovalbumin absorption pathways in the rat intestine, including the effects of aspirin.
Topics: Allergens; Animals; Arsenicals; Aspirin; beta-Cyclodextrins; Colchicine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Intestinal Absorption; Intestine, Small; Macrolides; Male; Ovalbumin; Rats, Sprague-Dawley; Serum Albumin, Bovine | 2014 |
Phenylarsine oxide as a redox modulator of transient receptor potential vanilloid type 1 channel function.
Topics: Adult; Animals; Arsenicals; Calcium; Capsaicin; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Humans; Membrane Potentials; Neurons; Oxidation-Reduction; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Sensory System Agents; TRPV Cation Channels | 2015 |
Inhibitory effect of snake venom toxin on NF-κB activity prevents human cervical cancer cell growth via increase of death receptor 3 and 5 expression.
Topics: Animals; Apoptosis; Arsenicals; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Mice, Inbred BALB C; NF-kappa B; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor, Member 25; TNF-Related Apoptosis-Inducing Ligand; Uterine Cervical Neoplasms; Viper Venoms; Xenograft Model Antitumor Assays | 2016 |
Active site targeting of hedgehog precursor protein with phenylarsine oxide.
Topics: Animals; Arsenicals; Catalytic Domain; Cholesterol; Dose-Response Relationship, Drug; Drosophila melanogaster; Gene Expression; Hedgehog Proteins; Humans; Hydrolysis; Kinetics; Models, Molecular; Protein Binding; Protein Precursors; Recombinant Fusion Proteins | 2015 |
Phosphatidylinositol 3-kinase and 4-kinase have distinct roles in intracellular trafficking of cellulose synthase complexes in Arabidopsis thaliana.
Topics: 1-Phosphatidylinositol 4-Kinase; Arabidopsis; Arabidopsis Proteins; Arsenicals; Cell Membrane; Chromones; Clathrin; Endocytosis; Glucosyltransferases; Golgi Apparatus; Green Fluorescent Proteins; Hypotonic Solutions; Intracellular Space; Models, Biological; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Transport; Thiazines; Time Factors | 2015 |
Identification of a novel stress regulated FERM domain containing cytosolic protein having PTP activity in Setaria cervi, a bovine filarial parasite.
Topics: Amino Acid Sequence; Animals; Arsenicals; Aspirin; Catalytic Domain; Cross Reactions; Cytosol; Female; Helminth Proteins; Humans; Molecular Sequence Data; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Setaria Nematode | 2015 |
ArsH is an organoarsenical oxidase that confers resistance to trivalent forms of the herbicide monosodium methylarsenate and the poultry growth promoter roxarsone.
Topics: Arsenicals; Biotransformation; Drug Resistance, Bacterial; Escherichia coli; Gene Deletion; Herbicides; Mutation; Operon; Oxidoreductases; Pseudomonas putida; Roxarsone | 2015 |
Phosphatidylinositol 4-phosphate negatively regulates chloroplast division in Arabidopsis.
Topics: 1-Phosphatidylinositol 4-Kinase; Arabidopsis; Arabidopsis Proteins; Arsenicals; Chloroplasts; Gene Deletion; Green Fluorescent Proteins; Intracellular Space; Lipid Metabolism; Phosphatidylinositol Phosphates; Protein Binding; Protein Kinase Inhibitors; Recombinant Proteins | 2015 |
A novel fluorescence-based biosynthetic trafficking method provides pharmacologic evidence that PI4-kinase IIIα is important for protein trafficking from the endoplasmic reticulum to the plasma membrane.
Topics: Androstadienes; Animals; Arsenicals; Cell Line, Tumor; Cell Membrane; Endoplasmic Reticulum; ErbB Receptors; Flow Cytometry; Fluorescent Dyes; Golgi Apparatus; GPI-Linked Proteins; Green Fluorescent Proteins; Membrane Proteins; Minor Histocompatibility Antigens; Phosphatidylinositol Phosphates; Phosphotransferases (Alcohol Group Acceptor); Protein Transport; Quercetin; Rats; Recombinant Fusion Proteins; Wortmannin | 2015 |
Rat Liver Mitochondrial Dysfunction Induced by an Organic Arsenical Compound 4-(2-Nitrobenzaliminyl) Phenyl Arsenoxide.
Topics: Animals; Arsenicals; Cell Membrane Permeability; Cell Respiration; Cyclosporine; Hydrogen; Lipid Peroxidation; Membrane Fluidity; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oxygen Consumption; Potassium; Rats | 2015 |
(E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice.
Topics: Allyl Compounds; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenicals; Cell Proliferation; Colonic Neoplasms; Cyclic S-Oxides; Dose-Response Relationship, Drug; fas Receptor; HCT116 Cells; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; NF-kappa B p50 Subunit; Phenols; Protein Binding; Receptors, Tumor Necrosis Factor, Member 25; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
To involvement the conformation of the adenine nucleotide translocase in opening the Tl(+)-induced permeability transition pore in Ca(2+)-loaded rat liver mitochondria.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Arsenicals; Atractyloside; Calcium; Cyclosporine; Ethylmaleimide; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Protein Conformation; Rats, Wistar; Sulfhydryl Compounds; tert-Butylhydroperoxide | 2016 |
Digestion and absorption of an egg white ACE-inhibitory peptide in human intestinal Caco-2 cell monolayers.
Topics: Androstadienes; Angiotensin-Converting Enzyme Inhibitors; Arsenicals; Biological Transport; Caco-2 Cells; Carrier Proteins; Cytochalasin D; Egg Proteins; Egg White; Humans; Peptide Fragments; Peptides; Sodium Azide; Wortmannin | 2016 |
Inhibition of Setaria cervi protein tyrosine phosphatases by Phenylarsine oxide: A proteomic and biochemical study.
Topics: Animals; Arsenicals; Buffaloes; Enzyme Inhibitors; Helminth Proteins; India; Protein Tyrosine Phosphatases; Proteomics; Setaria Nematode; Setariasis | 2016 |
Neuroprotective Effect of the Novel Compound ITH33/IQM9.21 Against Oxidative Stress and Na(+) and Ca(2+) Overload in Motor Neuron-like NSC-34 Cells.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arsenicals; Benzamides; Calbindin 1; Calcium; Cell Survival; Drug Evaluation, Preclinical; Glutamates; Mice; Mitochondria; Motor Neurons; Neuroprotective Agents; Oligomycins; Oxidative Stress; Parvalbumins; Riluzole; Rotenone; Sodium; Veratridine | 2016 |
Evaluation of Molecular Markers and Analytical Methods Documenting the Occurrence of Mustard Gas and Arsenical Warfare Agents in Soil.
Topics: Arsenicals; Biomarkers; Chemical Warfare Agents; Chromatography, Gas; Limit of Detection; Mustard Gas; Soil; Sulfhydryl Compounds | 2016 |
Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype.
Topics: Animals; Arsenicals; Cell Line; Cells, Cultured; Edema; Endoplasmic Reticulum Chaperone BiP; Erythema; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Humans; Inflammation; Keratinocytes; Mice; Mice, Knockout; Oxidative Stress; Patched-1 Receptor; Phenylbutyrates; RNA, Small Interfering; Transcription Factor CHOP; Unfolded Protein Response | 2016 |
Mercury and protein thiols: Stimulation of mitochondrial F
Topics: Adenosine Triphosphate; Animals; Arsenicals; Cell Respiration; Dithioerythritol; Electron Transport; Enzyme Activation; Kinetics; Magnesium; Mercury; Mitochondria; Mitochondrial Proteins; Proton-Translocating ATPases; Sulfhydryl Compounds; Sus scrofa | 2016 |
Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.
Topics: Arsenic; Arsenicals; Cross-Linking Reagents; Glutathione S-Transferase pi; Humans; Protein Multimerization; Protein Structure, Quaternary | 2017 |
Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Hazardous Substances; Toxicity Tests | 2016 |
On Chip Bioelectric Impedance Spectroscopy Reveals the Effect of P-Glycoprotein Efflux Pumps on the Paracellular Impedance of Tight Junctions at the Blood-Brain Barrier.
Topics: Animals; Arsenicals; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Dielectric Spectroscopy; Dogs; Electric Impedance; Enzyme Inhibitors; Madin Darby Canine Kidney Cells; Models, Biological; Tight Junctions | 2016 |
Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes.
Topics: Arsenicals; Arsenites; Drug Resistance, Neoplasm; Gene Expression; HEK293 Cells; Humans; Mutation; Promyelocytic Leukemia Protein; Protein Processing, Post-Translational; Proteolysis; Solubility | 2017 |
Interleukin-6 secreted by bipotential murine oval liver stem cells induces apoptosis of activated hepatic stellate cells by activating NF-κB-inducible nitric oxide synthase signaling.
Topics: Amidines; Animals; Apoptosis; Arsenicals; Benzylamines; Cell Differentiation; Cell Line, Transformed; Cells, Cultured; Culture Media, Conditioned; Gene Expression Regulation; Hepatic Stellate Cells; Imidazoles; Interleukin-6; Liver; Liver Cirrhosis; Mice; Models, Biological; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Quinoxalines; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Stem Cells | 2017 |
MAPK-mediated auxin signal transduction pathways regulate the malic acid secretion under aluminum stress in wheat (Triticum aestivum L.).
Topics: Aluminum; Arsenicals; Gene Expression Regulation, Plant; Indoleacetic Acids; Isotope Labeling; Malates; Mitogen-Activated Protein Kinases; Plant Proteins; Plant Roots; Protein Kinase Inhibitors; RNA, Plant; Signal Transduction; Stress, Physiological; Triticum | 2017 |
Receptor mediated endocytosis of vicilin in Callosobruchus maculatus (Coleoptera: Chrysomelidae) larval midgut epithelial cells.
Topics: Amino Acid Sequence; Animals; Arsenicals; Biological Transport; Carrier Proteins; Chlorpromazine; Coleoptera; Digestive System; Endocytosis; Epithelial Cells; Filipin; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Expression; Insect Proteins; Larva; Nystatin; Seed Storage Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Staining and Labeling | 2017 |
Phenylarsine oxide (PAO) induces apoptosis in HepG2 cells via ROS-mediated mitochondria and ER-stress dependent signaling pathways.
Topics: Apoptosis; Arsenicals; Carcinoma, Hepatocellular; Endoplasmic Reticulum Stress; Humans; Liver Neoplasms; Mitochondria; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured | 2017 |
Acute stimulatory effect of tumor necrosis factor on the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.
Topics: Animals; Arachidonic Acids; Arsenicals; Cyclic AMP-Dependent Protein Kinases; Isoquinolines; Kidney; Kidney Tubules; Loop of Henle; Male; Patch-Clamp Techniques; Phospholipase A2 Inhibitors; Phospholipases A2; Potassium Channels; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Rifabutin; Sulfonamides; Tumor Necrosis Factor-alpha | 2018 |
Phenylarsine Oxide Can Induce Degradation of PLZF-RARα Variant Fusion Protein of Acute Promyelocytic Leukemia.
Topics: Arsenicals; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion | 2019 |
Melatonin triggers the anticancer potential of phenylarsine oxide via induction of apoptosis through ROS generation and JNK activation.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenicals; Cell Line, Tumor; Enzyme Activation; Enzyme Activators; Humans; MAP Kinase Kinase 4; Melatonin; Neoplasms; Reactive Oxygen Species | 2020 |
Shifting the Specificity of
Topics: Arsenic; Arsenicals; Biosensing Techniques; Escherichia coli; Genetic Engineering | 2020 |
Phosphatidylinositol-4,5-Biphosphate (PI(4,5)P
Topics: Arsenicals; Calcium; Cell Membrane; Chromaffin Cells; Clathrin; Dithiothreitol; Endocytosis; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Signal Transduction | 2020 |
The mitochondrial F
Topics: Animals; Arsenicals; Bridged Bicyclo Compounds; Calcium; Cysteine; Dithioerythritol; Enzyme Activators; Enzyme Inhibitors; Magnesium; Mitochondria; Mitochondrial Permeability Transition Pore; Oxidation-Reduction; Oxidative Stress; Proton-Translocating ATPases; Swine | 2021 |
Development and Evaluation of a Topical Foam Formulation for Decontamination of Warfare Agents.
Topics: Animals; Arsenicals; Chemical Warfare Agents; Decontamination; Humans; Skin; Swine | 2022 |
Phenylarsine oxide inhibits the accumulation of lipid droplets in macrophages.
Topics: Arsenicals; Lipid Droplets; Lipid Metabolism; Macrophages | 2022 |
Retinal injury mouse model and pathophysiological assessment of the effect of arsenical vesicants.
Topics: Animals; Arsenicals; Cornea; Eye Injuries; Irritants; Mice; Retinal Diseases | 2023 |