oxidopamine has been researched along with dizocilpine maleate in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.16) | 18.7374 |
| 1990's | 46 (53.49) | 18.2507 |
| 2000's | 26 (30.23) | 29.6817 |
| 2010's | 13 (15.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| David, JC; Graybiel, AM; Paul, ML; Robertson, HA | 1 |
| Di Chiara, G; Fenu, S; Morelli, M | 1 |
| Di Chiara, G; Morelli, M; Orzi, F; Pontieri, FE; Terenzi, R | 1 |
| Di Chiara, G; Morelli, M | 2 |
| Breese, GR; Criswell, HE; Mueller, RA | 1 |
| Martin, GE; Papp, NL | 1 |
| Gancher, S; Mayer, A | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Bédard, PJ; St-Pierre, JA | 1 |
| Carta, A; Cozzolino, A; Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Daszuta, A; Forni, C; Moukhles, H; Nieoullon, A | 1 |
| Boldry, RC; Chase, TN; Engber, TM | 1 |
| Bronstein, DM; Hong, JS; Hudson, PM; Pennypacker, KR; Ye, H | 1 |
| Kerkerian-Le Goff, L; Nieoullon, A; Salin, P | 1 |
| Anderson, JJ; Boldry, RC; Chase, TN; Engber, TM; Kuo, S; Papa, SM | 1 |
| Greenamyre, JT | 1 |
| Anderson, JJ; Boldry, RC; Chase, TN; Engber, TM; Kuo, S | 1 |
| Pierce, RC; Rebec, GV | 1 |
| Amalric, M; Nieoullon, A; Ouagazzal, A | 1 |
| Goto, S; Inoue, N; Korematsu, K; Nagahiro, S; Oyama, T; Ushio, Y; Yamada, K | 1 |
| Boldry, RC; Chase, TN; Kask, AM; Papa, SM | 1 |
| Lapin, IP; Rogawski, MA | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Liste, I; Rozas, G | 1 |
| Emmi, A; Rajabi, H; Stewart, J | 1 |
| Hashiguchi, H; Ishida, Y; Kuwahara, I; Mitsuyama, Y; Nishimori, T; Todaka, K | 1 |
| Dall'Olio, R; Gandolfi, O | 1 |
| Carta, A; Di Chiara, G; Fenu, S; Morelli, M | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Kask, AM; Papa, SM | 1 |
| Bonastre, M; Chase, TN; Engber, TM; Marin, C; Papa, S; Tolosa, E | 1 |
| Barone, P; DiChiara, G; Morelli, M; Pellecchia, MT; Vallone, D; Verde, P | 1 |
| Brundin, P; Karlsson, J; Schierle, GS | 1 |
| Yone, K; Yoshino, S | 1 |
| Andrés, ME; Bustos, G; Gysling, K | 1 |
| Ishida, Y; Ishizuka, Y; Kuwahara, I; Mitsuyama, Y; Nakane, H; Nishimori, T; Todaka, K | 1 |
| Bergstrom, DA; Huang, KX; Ruskin, DN; Walters, JR | 1 |
| Choi, IG; Huh, SO; Ihn, BM; Jung, JS; Kim, YH; Song, DK; Suh, HW | 1 |
| Hashiguchi, H; Ishida, Y; Ishizuka, Y; Kuwahara, I; Mitsuyama, Y; Nishimori, T; Todaka, K | 1 |
| Lin, SM; Tseng, SH | 1 |
| Pollack, AE; Strauss, JB | 1 |
| Caruncho, HJ; Labandeira-Garcia, JL; Liste, I; Rodriguez-Pallares, J | 1 |
| Agid, Y; Hirsch, EC; Jimenez, A; Marin, C; Raisman-Vozari, R; Ruberg, M; Tolosa, E; Vila, M | 1 |
| Abarca, J; Bustos, G | 1 |
| de Groote, C; Eberhardt, O; Ferger, B; Schulz, JB; Teismann, P | 1 |
| Jenner, P; McNaught, KS | 1 |
| Dewar, KM; Elie, R; Vasiliadis, HM | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Liste, I; Muñoz, A | 1 |
| Breimer, DD; Danysz, W; De Boer, AG; Hesselink, MB; Smolders, H | 1 |
| Beani, L; Bianchi, C; Fuxe, K; Marti, M; Morari, M; Sbrenna, S | 1 |
| Ganguly, A; Keefe, KA | 1 |
| Bordet, R; Ridray, S; Schwartz, JC; Sokoloff, P | 1 |
| Bergmann, R; Gasparini, F; Kuhn, R; Spooren, WP | 1 |
| Ebinger, G; Jonkers, N; Michotte, Y; Sarre, S | 2 |
| Haisley, EC; Pollack, AE | 1 |
| Fujiwara, M; Hatip-Al-Khatib, I; Iwasaki, K; Mishima, K | 1 |
| Blandini, F; Fancellu, R; Greenamyre, JT; Nappi, G | 1 |
| Campbell, BM; Walker, PD | 1 |
| Ferger, B; Schmidt, N; Schulz, JB; Teismann, P; Xia, XG | 1 |
| Krentz, L; Meshul, CK; Moore, C; Robinson, S | 1 |
| Groenewegen, HJ; Van De Witte, SV; Voorn, P | 1 |
| Bölükbasi, F; Egashira, N; Fujiwara, M; Hatip-Al-khati, I; Iwasaki, K; Mishima, K | 1 |
| Inoue, O; Kagawa, S; Nakano, T; Nishimura, T | 1 |
| Bonastre, M; Hirsch, EC; Marin, C; Périer, C; Tolosa, E | 1 |
| Carta, AR; Morelli, M; Schibaev, NV; Vorobyov, VV | 1 |
| Nakagawa, M; Nishizawa, Y; Ogura, H; Ohgoh, M | 1 |
| Harris, RC; Kelsey, JE; Kleckner, NW; Mague, SD; Matthews, RT; Pijanowski, RS | 1 |
| Campbell, BM; Kreipke, CW; Walker, PD | 1 |
| Armentero, MT; Blandini, F; Bramanti, P; Fancellu, R; Nappi, G | 1 |
| Archer, T; Fredriksson, A | 1 |
| Sengpiel, F; Vorobyov, V | 1 |
| Jung, JS; Kim, DH; Moon, YS; Song, DK | 1 |
| Abarca, J; Bustos, G; Bustos, V; Campusano, J; Moya, C; Noriega, V; Riquelme, E | 1 |
| Akita, H; Honda, Y; Noda, K; Ogata, M; Saji, M | 1 |
| Anderson, AM; Johnson, SW; Lewis, JR; Meshul, CK; Paquette, MA; Paul Berger, S | 1 |
| Abraham, PM; Antony, S; Kuruvila, KP; Nandhu, MS; Paul, J; Paulose, CS | 1 |
| Deng, C; Huang, XF; Wang, Q; Wu, A; Xiong, Z; Xu, Y; Yan, J; Yang, Y; Yang, YG; Yenari, MA; Ying, W; Zhang, L; Zhu, C | 1 |
| Alvarez-Fischer, D; Bouillot, C; Castagner, F; Faigle, W; Fuchs, J; Hartmann, A; Joshi, RL; Lombès, A; Massiani-Beaudoin, O; Moya, KL; Oertel, WH; Prochiantz, A; Stettler, O | 1 |
| Akopian, G; Crawford, C; Jakowec, MW; Petzinger, G; Walsh, JP | 1 |
| Huston, JP; Petri, D; Pum, M; Schnitzler, A; Vesper, J | 1 |
| Ampe, B; Aourz, N; Bentea, E; De Deurwaerdère, P; El Arfani, A; Massie, A; Michotte, Y; Sarre, S; Smolders, I; Van Eeckhaut, A | 1 |
| Castro, AA; Dal-Cim, T; Lanznaster, D; Massari, CM; Tasca, CI | 1 |
| Mishra, A; Shukla, S; Singh, S; Srivastava, N | 1 |
| Belforte, JE; Braz, BY; Galiñanes, GL; Murer, MG | 1 |
| Chen, SY; Shao, B; Wang, XS; Xie, CL; Zhang, XR; Zhang, ZR | 1 |
| Bartlett, MJ; Falk, T; Flores, AJ; Heien, ML; Parent, KL; Polt, R; Porreca, F; Root, BK; Sherman, SJ | 1 |
1 review(s) available for oxidopamine and dizocilpine maleate
| Article | Year |
|---|---|
Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Haplorhini; Humans; Mice; MPTP Poisoning; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Quinoxalines; Rats; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1993 |
85 other study(ies) available for oxidopamine and dizocilpine maleate
| Article | Year |
|---|---|
D1-like and D2-like dopamine receptors synergistically activate rotation and c-fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amino Acid Sequence; Animals; Behavior, Animal; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Ergolines; Male; Molecular Sequence Data; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1992 |
Blockade of N-methyl-D-aspartate receptors potentiates dopaminergic responses in the 6-OHDA model of Parkinson: differential role of D-1 and D-2 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Dizocilpine Maleate; Dopamine; Drug Synergism; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1992 |
Metabolic mapping of the synergism between MK-801 and SKF 38393 in rats with unilateral lesions of the dopaminergic nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Synergism; Glucose; Male; Neural Pathways; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1992 |
MK-801 potentiates dopaminergic D1 but reduces D2 responses in the 6-hydroxydopamine model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Dizocilpine Maleate; Dopamine Agents; Ergolines; Hydroxydopamines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Stereotyped Behavior | 1990 |
Stereospecific blockade of N-methyl-D-aspartate transmission by MK 801 prevents priming of SKF 38393-induced turning.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hydroxydopamines; Male; N-Methylaspartate; Oxidopamine; Rats; Rats, Inbred Strains; Stereoisomerism; Stereotyped Behavior; Sympathectomy, Chemical; Synaptic Transmission | 1990 |
Long-term D1-dopamine receptor sensitization in neonatal 6-OHDA-lesioned rats is blocked by an NMDA antagonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hydroxydopamines; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Blockade of MK-801 induced ipsiversive turning in 6-OHDA lesioned rats by alpha 1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Amphetamine; Animals; Anticonvulsants; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Butyrophenones; Dibenzazepines; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Humans; Hydroxydopamines; Oxidopamine; Postural Balance; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1984 |
Sensitization to apomorphine-induced rotational behavior in 6-OHDA-lesioned rats: effects of NMDA antagonists on drug response.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1995 |
Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Immunohistochemistry; Injections; Male; Neostriatum; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1995 |
Intranigral but not intrastriatal microinjection of the NMDA antagonist MK-801 induces contralateral circling in the 6-OHDA rat model.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Female; Functional Laterality; Microinjections; Motor Activity; N-Methylaspartate; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Substantia Nigra | 1994 |
Differential effect of MK 801 and scopolamine on c-fos expression induced by L-dopa in the striatum of 6-hydroxydopamine lesioned rats.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Immunohistochemistry; Levodopa; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Stereotyped Behavior | 1994 |
Regulation of dopamine levels in intrastriatal grafts of fetal mesencephalic cell suspension: an in vivo voltammetric approach.
Topics: 2-Amino-5-phosphonovalerate; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzazepines; Brain Tissue Transplantation; Cerebral Ventricles; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Female; Fetal Tissue Transplantation; Glutamic Acid; Injections, Intraventricular; Kinetics; Mesencephalon; N-Methylaspartate; Oxidopamine; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Dopamine D1; Sulpiride; Time Factors; Transplantation, Heterotopic | 1994 |
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Diseases; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Levodopa; Male; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1993 |
Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Base Sequence; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dynorphins; Ergolines; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Immediate-Early Proteins; Male; Molecular Sequence Data; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1994 |
Reversal of the adaptive response of neuropeptide Y neurons in the rat striatum to nigrostriatal dopamine deafferentation by the N-methyl-D-aspartate antagonist dizocilpine maleate.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Dizocilpine Maleate; Female; Immunohistochemistry; N-Methylaspartate; Neostriatum; Neural Pathways; Neurons; Neurons, Afferent; Neuropeptide Y; Oxidopamine; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission | 1994 |
Excitatory amino acid receptor antagonists modify regional cerebral metabolic responses to levodopa in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Deoxyglucose; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Organ Specificity; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley | 1994 |
N-methyl-D-aspartate receptor blockade differentially modifies regional cerebral metabolic responses to D1 and D2 dopamine agonists in rats with a unilateral 6-hydroxydopamine lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Chemistry; Corpus Striatum; Deoxyglucose; Dizocilpine Maleate; Dopamine Agents; Ergolines; Glucose; Male; Neural Pathways; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra | 1993 |
Intraneostriatal administration of glutamate antagonists increases behavioral activation and decreases neostriatal ascorbate via nondopaminergic mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Dizocilpine Maleate; Glutamates; Glutamic Acid; Homocysteine; Infusions, Parenteral; Male; Motor Activity; Neostriatum; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1993 |
Locomotor activation induced by MK-801 in the rat: postsynaptic interactions with dopamine receptors in the ventral striatum.
Topics: Amphetamine; Animals; Brain; Brain Diseases; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Drug Interactions; Haloperidol; Male; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synapses | 1994 |
N-methyl-D-aspartate receptor antagonist MK-801 induced circling behavior in rats with unilateral striatal ischemic lesions or nigral 6-hydroxydopamine lesions.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ischemic Attack, Transient; Motor Activity; Neostriatum; Oxidopamine; Rats; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra | 1993 |
MK-801 reverses effects of chronic levodopa on D1 and D2 dopamine agonist-induced rotational behavior.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Ergolines; Excitatory Amino Acid Antagonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympatholytics | 1995 |
Effects of D1 and D2 dopamine receptor antagonists and catecholamine depleting agents on the locomotor stimulation induced by dizocilpine in mice.
Topics: Animals; Brain; Brain Mapping; Catecholamines; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurons; Norepinephrine; Oxidopamine; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1995 |
Cortical stimulation induces Fos expression in striatal neurons via NMDA glutamate and dopamine receptors.
Topics: Animals; Benzazepines; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electric Stimulation; Female; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 1995 |
Behavioral and neurochemical recovery from partial 6-hydroxydopamine lesions of the substantia nigra is blocked by daily treatment with glutamate receptor antagonists MK-801 and CPP.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Piperazines; Rats; Rats, Wistar; Substantia Nigra | 1996 |
Dopaminergic transplants suppress L-DOPA-induced Fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease.
Topics: Animals; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Dizocilpine Maleate; Dopamine; Female; Fetal Tissue Transplantation; Levodopa; Mesencephalon; Methamphetamine; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase | 1996 |
Modulatory role of dopamine on excitatory amino acid receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Guanylyl Imidodiphosphate; Male; Oxidopamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sympatholytics | 1996 |
Effect of MK 801 on priming of D1-dependent contralateral turning and its relationship to c-fos expression in the rat caudate-putamen.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caudate Nucleus; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; N-Methylaspartate; Oxidopamine; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Synaptic Transmission | 1996 |
Reversal of levodopa-induced motor fluctuations in experimental parkinsonism by NMDA receptor blockade.
Topics: Animals; Antiparkinson Agents; Apomorphine; Benserazide; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections; Injections, Intraventricular; Levodopa; Male; Movement; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rotation; Stereotyped Behavior; Substantia Nigra | 1995 |
MK-801 prevents levodopa-induced motor response alterations in parkinsonian rats.
Topics: Animals; Antiparkinson Agents; Benserazide; Dizocilpine Maleate; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Prosencephalon; Rats; Rats, Sprague-Dawley; Rotation | 1996 |
Behavioural sensitization in 6-hydroxydopamine-lesioned rats is related to compositional changes of the AP-1 transcription factor: evidence for induction of FosB- and JunD-related proteins.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Cell Nucleus; Corpus Striatum; Denervation; Dizocilpine Maleate; Gene Expression Regulation; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Transcription Factor AP-1 | 1997 |
MK-801 does not enhance dopaminergic cell survival in embryonic nigral grafts.
Topics: Animals; Brain Tissue Transplantation; Cell Survival; Dizocilpine Maleate; Female; Fetal Tissue Transplantation; Graft Survival; Mesencephalon; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 1998 |
Role of norepinephrine and excitatory amino acids in edema of the spinal cord after experimental compression injury in rats.
Topics: Analysis of Variance; Animals; Body Water; Disease Models, Animal; Dizocilpine Maleate; Edema; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Injections, Spinal; Male; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Reference Values; Spinal Cord; Spinal Cord Compression; Statistics, Nonparametric | 1998 |
Differential regulation of dopamine release by N-methyl-D-aspartate receptors in rat striatum after partial and extreme lesions of the nigro-striatal pathway.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Neural Pathways; Oxidopamine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Sympatholytics | 1998 |
Methamphetamine-induced Fos expression in the substantia nigra pars reticulata in rats with a unilateral 6-OHDA lesion of the nigrostriatal fibers.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Methamphetamine; Nerve Fibers; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics; Sympathomimetics; Tyrosine 3-Monooxygenase | 1998 |
N-methyl-D-aspartate receptor blockade attenuates D1 dopamine receptor modulation of neuronal activity in rat substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reserpine; Stereotaxic Techniques; Substantia Nigra | 1998 |
Central GABAA and GABAB receptor modulation of basal and stress-induced plasma interleukin-6 levels in mice.
Topics: Animals; Baclofen; Brain; Dizocilpine Maleate; GABA Modulators; Injections, Intraventricular; Interleukin-6; Male; Mice; Mice, Inbred ICR; Muscimol; Oxidopamine; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Stress, Physiological | 1998 |
Methamphetamine induces fos expression in the striatum and the substantia nigra pars reticulata in a rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Mesencephalon; Methamphetamine; Neurons; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Salicylamides; Substantia Nigra; Sympatholytics; Tyrosine 3-Monooxygenase | 1998 |
Substantia nigra lesion suppresses the antagonistic effects of N-methyl-D-aspartate receptor antagonist (MK-801) on the autotomy in the rat.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Ganglia, Spinal; Ganglionectomy; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Self Mutilation; Substantia Nigra; Time Factors | 1998 |
Time dependence and role of N-methyl-D-aspartate glutamate receptors in the priming of D2-mediated rotational behavior and striatal Fos expression in 6-hydroxydopamine lesioned rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Nerve Degeneration; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Sympatholytics; Time Factors | 1999 |
Locomotor-activity-induced changes in striatal levels of preprotachykinin and preproenkephalin mRNA. Regulation by the dopaminergic and glutamatergic systems.
Topics: Animals; Apomorphine; Benzazepines; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Running; Tachykinins | 1999 |
Systemic administration of NMDA and AMPA receptor antagonists reverses the neurochemical changes induced by nigrostriatal denervation in basal ganglia.
Topics: Animals; Basal Ganglia; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Electron Transport Complex IV; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Isoquinolines; Levodopa; Male; N-Methylaspartate; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Substantia Nigra; Tetrazoles | 1999 |
Differential regulation of glutamate, aspartate and gamma-amino-butyrate release by N-methyl-D-aspartate receptors in rat striatum after partial and extensive lesions to the nigro-striatal dopamine pathway.
Topics: Animals; Aspartic Acid; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Homeostasis; Kinetics; Male; Microdialysis; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1999 |
Malonate-induced generation of reactive oxygen species in rat striatum depends on dopamine release but not on NMDA receptor activation.
Topics: Animals; Dizocilpine Maleate; Dopamine; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Male; Malonates; Microdialysis; Neostriatum; Oxidopamine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Succinate Dehydrogenase | 1999 |
Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Coculture Techniques; Dizocilpine Maleate; Dopamine; Electron Transport Complex I; Excitatory Amino Acid Antagonists; Glutathione; Lipopolysaccharides; Mesencephalon; NADH, NADPH Oxidoreductases; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1999 |
Interaction between dopamine and glutamate receptors following treatment with NMDA receptor antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Fenfluramine-induced increase in preproenkephalin mRNA levels in the striatum: interaction between the serotonergic, glutamatergic, and dopaminergic systems.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Enkephalins; Female; Fenfluramine; Oxidopamine; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin Agents | 2000 |
Modifications of the behavioral profile of non-competitive NMDA receptor antagonists, memantine, amantadine and (+)MK-801 after chronic administration.
Topics: Amantadine; Animals; Ataxia; Avoidance Learning; Behavior, Animal; Catalepsy; Dizocilpine Maleate; Drug Implants; Excitatory Amino Acid Antagonists; Male; Memantine; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Sympathectomy, Chemical; Sympathomimetics; Time Factors | 1999 |
Increased responsivity of glutamate release from the substantia nigra pars reticulata to striatal NMDA receptor blockade in a model of Parkinson's disease. A dual probe microdialysis study in hemiparkinsonian rats.
Topics: Animals; Corpus Striatum; Denervation; Dizocilpine Maleate; Functional Laterality; Glutamic Acid; Male; Microdialysis; Neurons; Oxidopamine; Parkinsonian Disorders; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 2000 |
Effects of MK-801 on D1 dopamine receptor-mediated immediate early gene expression in the dopamine-depleted striatum.
Topics: Animals; Benzazepines; Brain; Dizocilpine Maleate; DNA-Binding Proteins; Dopamine; Dopamine Agonists; Early Growth Response Protein 1; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Immediate-Early Proteins; Male; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Transcription Factors | 2000 |
Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Antiparkinson Agents; Benzazepines; Binding, Competitive; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression; Levodopa; Male; Neural Pathways; Neurons; Opioid Peptides; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substantia Nigra; Sympatholytics; Tachykinins; Tetrahydronaphthalenes; Tritium; Ventral Tegmental Area | 2000 |
Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats.
Topics: Animals; Apomorphine; Dextroamphetamine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Oxidopamine; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Rotation | 2000 |
MK801 influences L-DOPA-induced dopamine release in intact and hemi-parkinson rats.
Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Corpus Striatum; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra | 2000 |
NMDA glutamate receptor stimulation is required for the expression of D2 dopamine mediated responses in apomorphine primed 6-hydroxydopamine lesioned rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Denervation; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Parkinson Disease; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Sympatholytics | 2001 |
Microdialysates of amines and metabolites from core nucleus accumbens of freely moving rats are altered by dizocilpine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzylamines; Chromatography, High Pressure Liquid; Desipramine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Reserpine; Serotonin | 2001 |
Blockade of subthalamic glutamatergic activity corrects changes in neuronal metabolism and motor behavior in rats with nigrostriatal lesions.
Topics: Amphetamine; Animals; Dizocilpine Maleate; Energy Metabolism; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Male; Motor Activity; Neostriatum; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Succinate Dehydrogenase; Sympatholytics; Synaptic Transmission | 2001 |
NMDA receptor antagonism modifies the synergistic regulation of striatal tachykinin gene expression induced by dopamine D(1) and serotonin(2) receptor stimulation following neonatal dopamine depletion.
Topics: Animals; Animals, Newborn; Corpus Striatum; Denervation; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Substance P; Sympatholytics | 2001 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbidopa; Carrier Proteins; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Oxidopamine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reserpine; Succinate Dehydrogenase; Sulpiride; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2001 |
Blockade of NMDA receptors by MK-801 reverses the changes in striatal glutamate immunolabeling in 6-OHDA-lesioned rats.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunochemistry; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synapses | 2001 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Immunohistochemistry; Levodopa; Male; Motor Activity; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Tyrosine 3-Monooxygenase | 2002 |
MK801 suppresses the L-DOPA-induced increase of glutamate in striatum of hemi-Parkinson rats.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Sympatholytics; Synaptic Transmission | 2002 |
Role of dopaminergic system in core part of nucleus accumbens in hyperlocomotion and rearing induced by MK-801 in rats: a behavioral and in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dopamine; Electrochemistry; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Oxidopamine; Rats; Rats, Wistar; Serotonin; Stereotaxic Techniques; Sympathectomy, Chemical; Sympatholytics | 2001 |
Effect of glutamatergic systems on in vivo binding of [(125)I]beta-CIT in the brain of a rat model of Parkinson's disease.
Topics: Animals; Autoradiography; Binding, Competitive; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Serotonin; Sympatholytics | 2002 |
AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6-OHDA-lesioned-rats treated with L-dopa.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Isoquinolines; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tetrazoles | 2002 |
EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2003 |
Dopaminergic agonists and muscarinic antagonists improve lateralization in hemiparkinsonian rats in a novel exploratory Y-maze.
Topics: Animals; Antiparkinson Agents; Cholinergic Antagonists; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Functional Laterality; Levodopa; Male; Muscarinic Antagonists; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar | 2004 |
NMDA receptor antagonists ameliorate the stepping deficits produced by unilateral medial forebrain bundle injections of 6-OHDA in rats.
Topics: Adrenergic Agents; Animals; Brain; Dizocilpine Maleate; Dopamine Agents; Drug Interactions; Gait; Levodopa; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Receptors, N-Methyl-D-Aspartate | 2004 |
Failure of MK-801 to suppress D1 receptor-mediated induction of locomotor activity and striatal preprotachykinin mRNA expression in the dopamine-depleted rat.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Down-Regulation; Drug Synergism; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Up-Regulation | 2006 |
Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease.
Topics: Animals; Cell Survival; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Electron Transport Complex IV; Energy Metabolism; Excitatory Amino Acid Antagonists; Male; Nerve Degeneration; Neural Pathways; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus | 2006 |
Behavioural supersensitivity following neonatal 6-hydroxydopamine: attenuation by MK-801.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Hyperkinesis; Male; Motor Activity; Neuroprotective Agents; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Time Factors | 2007 |
Apomorphine-induced differences in cortical and striatal EEG and their glutamatergic mediation in 6-hydroxydopamine-treated rats.
Topics: Alpha Rhythm; Animals; Apomorphine; Behavior, Animal; Beta Rhythm; Cerebral Cortex; Corpus Striatum; Delta Rhythm; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Osmotic Fragility; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Sympatholytics; Theta Rhythm | 2008 |
Central or peripheral norepinephrine depletion enhances MK-801-induced plasma corticosterone level in mice.
Topics: Animals; Brain; Corticosterone; Dizocilpine Maleate; Hypothalamus; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-6; Male; Mice; Mice, Inbred ICR; Norepinephrine; Oxidopamine; Spleen | 2009 |
NMDA receptors mediate an early up-regulation of brain-derived neurotrophic factor expression in substantia nigra in a rat model of presymptomatic Parkinson's disease.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain-Derived Neurotrophic Factor; Cell Count; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Male; Microdialysis; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2009 |
Activation of the NMDA receptor involved in the alleviating after-effect of repeated stimulation of the subthalamic nucleus on motor deficits in hemiparkinsonian rats.
Topics: Animals; Deep Brain Stimulation; Dizocilpine Maleate; Dyskinesias; Excitatory Amino Acid Antagonists; Forelimb; Male; Motor Activity; Neuropsychological Tests; Oxidopamine; Parkinsonian Disorders; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Subthalamic Nucleus; Time Factors | 2010 |
MK-801 inhibits L-DOPA-induced abnormal involuntary movements only at doses that worsen parkinsonism.
Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotation; Time Factors | 2010 |
Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson's rat: functional recovery with bone marrow cells, serotonin and GABA.
Topics: Animals; bcl-2-Associated X Protein; Binding, Competitive; Cerebellar Diseases; Cerebellum; Cyclic AMP; Dizocilpine Maleate; Inositol Phosphates; Male; Microscopy, Confocal; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents; Anxiety; Apoptosis; Autoradiography; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Glutamic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Matrix Metalloproteinase 9; Nerve Degeneration; Oxidopamine; Parkinson Disease; PC12 Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Simvastatin; Substantia Nigra; Tritium; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2011 |
Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.
Topics: alpha-Synuclein; Animals; Cell Count; Cells, Cultured; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electron Transport Chain Complex Proteins; Embryo, Mammalian; Homeodomain Proteins; In Vitro Techniques; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADH Dehydrogenase; Nerve Tissue Proteins; Neurons; Neurotoxins; Nitro Compounds; Oxidopamine; Propionates; RNA, Small Interfering; Rotenone; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 2011 |
Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Benzazepines; Biophysics; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Functional Laterality; In Vitro Techniques; Movement; Nitro Compounds; Oxidopamine; Propionates; Protein Binding; Rats; Rats, Inbred F344; Substantia Nigra; Sulpiride; Synapses; Time Factors; Tritium; Tyrosine 3-Monooxygenase | 2012 |
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Functional Laterality; GABA-A Receptor Agonists; Homovanillic Acid; Male; Medial Forebrain Bundle; Mental Disorders; Muscimol; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptors, GABA-A; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2013 |
NMDA receptor antagonism potentiates the L-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats.
Topics: Animals; Antiparkinson Agents; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Functional Laterality; Glutamic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Parkinsonian Disorders; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus | 2014 |
In vitro 6-hydroxydopamine-induced toxicity in striatal, cerebrocortical and hippocampal slices is attenuated by atorvastatin and MK-801.
Topics: Animals; Atorvastatin; Cell Survival; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidopamine; Rats, Wistar; Reactive Oxygen Species | 2016 |
MK-801 (Dizocilpine) Regulates Multiple Steps of Adult Hippocampal Neurogenesis and Alters Psychological Symptoms via Wnt/β-Catenin Signaling in Parkinsonian Rats.
Topics: Adaptation, Ocular; Animals; beta Catenin; Cell Proliferation; Disease Models, Animal; Dizocilpine Maleate; Exploratory Behavior; Hippocampus; Ki-67 Antigen; Male; Mood Disorders; Motor Activity; Neurogenesis; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Wnt Proteins; Wnt Signaling Pathway | 2017 |
Properties of the corticostriatal long term depression induced by medial prefrontal cortex high frequency stimulation in vivo.
Topics: Adrenergic Agents; Animals; Animals, Newborn; Benzazepines; Choline O-Acetyltransferase; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Heparin-binding EGF-like Growth Factor; Long-Term Synaptic Depression; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Oxidopamine; Piperidines; Prefrontal Cortex; Pyrazoles; Receptor, Cannabinoid, CB1; Tyrosine 3-Monooxygenase | 2017 |
Modulation of CaMKIIa-GluN2B interaction in levodopa-induced dyskinesia in 6-OHDA-lesioned Parkinson's rats.
Topics: Animals; Behavior, Animal; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corpus Striatum; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Levodopa; Male; Neurons; Oxidopamine; Parkinson Disease; Phosphorylation; Protein Binding; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfonamides | 2018 |
The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Benzazepines; Dizocilpine Maleate; Drug Synergism; Dyskinesia, Drug-Induced; Glycopeptides; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats | 2018 |