oxazolidin-2-one has been researched along with zolmitriptan in 409 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 94 (22.98) | 18.2507 |
| 2000's | 200 (48.90) | 29.6817 |
| 2010's | 96 (23.47) | 24.3611 |
| 2020's | 19 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Cox, RC; Ferrari, MD; Jones, D; Klein, KB; Visser, WH | 1 |
| Ferrari, MD | 3 |
| Earl, NL | 1 |
| Martin, GR | 2 |
| Geraud, GE | 1 |
| Dowson, A | 2 |
| Edmeads, JG | 1 |
| Bendtsen, L; Daugaard, D; Dixon, R; Gibbens, M; Langemark, M; Lassen, LH; Olesen, J; Thomsen, LL | 1 |
| Churchus, R; On, N; Phillips, S; Posner, J; Rolan, P; Seaber, E | 1 |
| Goadsby, PJ; Hoskin, KL | 2 |
| Goadsby, PJ; Olesen, J | 1 |
| Zagami, AS | 2 |
| Dowson, AJ | 1 |
| Dixon, R; Gibbens, M; Gillotin, C; Peck, RW; Posner, J | 1 |
| Barrett, VJ; Buckingham, J; Giles, H; Honey, AC; MacLennan, SJ; Martin, GR; Moncada, S; Prentice, DJ; Robertson, AD | 1 |
| Goadsby, PJ; Knight, YE | 1 |
| Chittick, G; Dixon, RM; Gibbens, M; Leavens, WJ; Liptrot, J; On, N; Pack, RW; Posner, J; Rolan, PE; Seaber, E | 1 |
| Goadsby, PJ | 3 |
| Schoenen, J | 1 |
| Dahlöf, C | 3 |
| Dixon, RM; Evans, DH; Meire, HB; On, N; Posner, J; Rolan, PE; Watt, H | 1 |
| Castro, ME; Pascual, J; Pazos, A | 1 |
| Cutrer, FM; Moskowitz, MA | 1 |
| Adelman, JU; Earl, NL; Elkind, AH; Kudrow, DB; Mathew, NT; Ramadan, NM; Rapoport, AM | 1 |
| Cady, RK; Earl, NL; Klapper, JA; Ramadan, NM; Saper, JR; Solomon, GD | 1 |
| Mathew, N | 1 |
| Dixon, R; Warrander, A | 1 |
| Rolan, P | 1 |
| Sawyer, J; Schoenen, J | 1 |
| Edmeads, JG; Millson, DS | 1 |
| Lipton, RB; Stewart, WF | 1 |
| Bagnis, C; Deray, G; Gillotin, C; Mamet, JP; Peck, RW | 1 |
| Dixon, R; Gillotin, CG; Layton, G; Peck, RW; Posner, J; Seaber, EJ; Weatherley, BC | 1 |
| Goadsby, PJ; Storer, RJ | 1 |
| Afra, J; Proietti-Cecchini, A; Schoenen, J | 1 |
| Layton, G; Peck, RW; Posner, J; Ridout, G; Seaber, EJ | 1 |
| Colpaert, FC; John, GW; Pagniez, F; Valentin, JP; Vieu, S | 1 |
| Arnold, G; Back, T; Dirnagl, U; Dreier, J; Einhäupl, KM; Gold, L; Reuter, U | 1 |
| Dixon, RM; Jackson, SH; Layton, GR; Peck, RW; Posner, J; Rolan, PE; Seaber, EJ; Weatherley, BC | 1 |
| Guanci, R; Lilley, LL | 1 |
| Cleary, EW; Huffman, CS; Polvino, WJ; Smith, DA; Watkins, S | 1 |
| Cleary, EW; Dilzer, SC; Huffman, CS; Lasseter, KC; Smith, DA; Watkins, S | 1 |
| Delvaux, M; Dixon, R; French, S; Kemp, J; Leclerc, V; Rautureau, J; Sellers, M | 1 |
| John, GW; Le Grand, B; Vié, B | 1 |
| Förderreuther, S; Straube, A; Werhahn, KJ | 1 |
| Dixon, R; Hughes, AM; Kemp, JV; Nairn, K; Sellers, M; Yates, RA | 1 |
| Allanson, J; Hefting, NR; Jonkman, JH; Peck, RW; Seaber, EJ; Smith, DA; Sollie, FA; van Lier, JJ; Wemer, J | 1 |
| Pascual, J | 1 |
| Leira, R; Noya, M | 1 |
| Morales Asín, F | 1 |
| Cambridge, D; MacLennan, SJ; Marston, C; Martin, GR; Whiting, MV | 1 |
| Cumberbatch, MJ; Hargreaves, RJ; Hill, RG | 1 |
| Lohman, JJ; van der Kuy, PH | 1 |
| Meijler, W | 1 |
| Gibbens, M; Lamb, RJ; Mercer, AJ; Posner, J; Rolan, PE | 1 |
| Monseu, G; Sternon, J | 1 |
| Diener, HC; Fritsche, G; Kazarawa, Z; Limmroth, V | 1 |
| Hopkins, B; McHarg, A; Melrose, H; Napier, C; Stewart, M; Wallis, R | 1 |
| Cummings, L; Dane, A; Dixon, R; Hughes, AM; Kemp, J; Yates, RA | 1 |
| Dixon, R; Engleman, K; Kemp, J; Ruckle, JL | 1 |
| Bard, JA; Branchek, T; Edvinsson, L; Longmore, J; Nilsson, T; Pantev, E; Shaw, D | 1 |
| Bungay, PJ; George, SE; Kemp, DM; Naylor, LH | 1 |
| Birk, KL; Cohen, AF; De Puy, ME; De Smet, M; Fisher, AL; Goldberg, MR; Musson, DG; Sterrett, A; Van Gerven, JM; Van Haarst, AD | 1 |
| Deleu, D; Hanssens, Y | 2 |
| Bhagwagar, Z; Cowen, PJ; Whale, R | 1 |
| Gunasekara, NS; Hills, C; Spencer, CM | 1 |
| Diener, HC; Limmroth, V | 1 |
| Buzzi, MG | 1 |
| Le Jeunne, C | 1 |
| Dixon, R | 1 |
| Butters, CJ; McKillop, D; Wild, MJ | 1 |
| Diener, HC; Dowson, AJ; Ferrari, M; Nappi, G; Tfelt-Hansen, P | 1 |
| Amelin, AV; Korenko, LA; Skoromets, AA | 1 |
| Bartlett, MG; Stewart, JT; Vishwanathan, K | 1 |
| Bomhof, MA; Donnan, GA; Dowson, AJ; Elkind, A; Fletcher, PE; Meloche, J; Millson, DS; Tepper, SJ | 1 |
| Edvinsson, L; Geraud, G; Korczyn, A; Mauskop, A; Pfaffenrath, V; Tuchman, M | 1 |
| Farkkila, M; Hering-Hanit, R; Mauskop, A; Rapoport, A; Warner, J | 1 |
| Logemann, CD; Rankin, LM | 1 |
| Millson, DS | 1 |
| Chalimoniuk, M; Stepień, A; Strosznajder, J | 1 |
| Ferrari, MD; Lamers, FP; Roon, KI; Sándor, PS; Schoenen, J; Schoonman, GG; van Dijk, JG | 1 |
| Nater, B; Regli, F | 1 |
| Peacock, JH; Vijayan, N | 1 |
| Chitra, R; Dennish, G; Gallagher, RM; Spierings, EL | 1 |
| Duckmanton, L | 1 |
| Bahra, A; Breen, SA; Gawel, MJ; Goadsby, PJ; Hardebo, JE; Millson, D | 1 |
| Diener, HC; Geraud, G; Olesen, J; Pfaffenrath, V; Sweet, R; Tfelt-Hansen, P; Zupping, R | 1 |
| Bjork, JM; Dougherty, DM; Marsh, DM; Moeller, FG; Swann, AC; Van de Kar, LD | 1 |
| John, GW; Le Grand, B; Panissié, A; Pauwels, PJ; Perez, M | 1 |
| Chernyshev, O; Gentry, P; Kailasam, J; Mathew, NT | 1 |
| de Tommaso, M; Guido, M; Libro, G; Puca, F; Sciruicchio, V | 1 |
| Bartleson, JD | 1 |
| Tfelt-Hansen, P | 2 |
| Ellis, MR; Encarnacion, JR; Lindbloom, EJ | 1 |
| Allen, C; Diener, HC; Pascual, J; Patel, K; Vega, P; Vrijens, F | 1 |
| Boshuisen, ML; den Boer, JA | 1 |
| de Hoon, JN; Struijker-Boudier, HA; Troost, J; Van Bortel, LM; Willigers, JM | 1 |
| Scholz, M | 1 |
| Dowson, AJ; Linder, SL | 1 |
| Bernstein, W | 1 |
| Prusiński, A | 1 |
| Potrebic, S; Raskin, NH | 1 |
| Croft, P; Frischer, M; Goadsby, PJ; Millson, D | 1 |
| McGinnis, J; Seaton, TL | 1 |
| Becker, WJ | 1 |
| Gruffyd-Jones, K; Kies, B; Middleton, A; Millson, DS; Mulder, LJ; Røsjø , Ø | 1 |
| Bhagwagar, Z; Clifford, EM; Cowen, PJ; Whale, R | 1 |
| Galli, F; Guidetti, V | 1 |
| Hashimoto, S; Iwata, M | 1 |
| Marcus, DA | 1 |
| Johnson, DE; McHarg, AD; Rollema, H; Schmidt, AW | 1 |
| Leira, R; Muñoz, R; Pascual, J | 1 |
| Rapoport, AM; Tepper, SJ | 1 |
| Saper, JR | 1 |
| Goadsby, PJ; Jiang, K; Lines, CR; Lipton, RB; Massiou, H; McCarroll, KA; Pascual, J; Vandormael, K | 1 |
| de Almeida, RM; Faccidomo, S; Fish, EW; Miczek, KA; Nikulina, EM | 1 |
| Dowson, AJ; Rapoport, AM; Sawyer, J; Williams, P | 1 |
| Adelman, JU; Diener, HC; Ferrari, MD; Lines, CR; Lipton, RB; McCarroll, KA; Vandormael, K | 1 |
| Billeter, M; Daems, K; Sturzenegger, M | 1 |
| Diener, HC; Fritsche, G; Katsarava, Z; Limmroth, V; Muessig, M | 1 |
| Clement, EM; Franklin, M | 1 |
| Compagnon, A; Geraud, G; Rossi, A | 1 |
| Henry, P | 1 |
| Charlesworth, B | 1 |
| Meddis, D; Millson, D; Poole, L; Sculpher, M | 1 |
| Freitag, FG | 1 |
| Diener, HC; Drepper, J; Ellrich, J; Katsarava, Z; Kaube, H; Przywara, S | 1 |
| Becker, WJ; Dowson, AJ; Green, J; Levy, SL; MacGregor, EA; Purdy, RA | 1 |
| Bellaïche, G; Boucard, M; Ley, G; Radu, B; Slama, JL | 1 |
| Fité, B; López-Gil, A; Pascual, J | 1 |
| Charlesworth, B; Dowson, AJ | 1 |
| Fukuuchi, Y; Itoyama, Y; Iwata, M; Morimatsu, M; Nakashima, K; Sakai, F; Sobue, G; Tashiro, K; Tsuji, S | 1 |
| Rapoport, AM; Sheftell, FD; Tepper, SJ | 1 |
| Csiba, L; Ficzere, A | 1 |
| Dane, A; Ikegami, A; Kemp, J; Nairn, K; Tateno, M; Yates, RA | 1 |
| Angstwurm, K; Bille, MB; Dirnagl, U; Hoffmann, O; Keilwerth, N; Reuter, U; Schumann, RR; Weber, JR | 1 |
| Bussone, G; D'Amico, D; Gerth, W; Lines, CR; McCarroll, KA | 1 |
| De Almeida, RM; De Bold, JF; Fish, EW; Miczek, KA | 1 |
| Dixon, R; Nairn, K; Seaber, E; Yates, R | 1 |
| Dane, AL; Dixon, R; Kemp, JV; Nairn, K; Yates, R | 1 |
| Boes, CJ; Goadsby, PJ | 1 |
| Aubel, B; Bourgoin, S; Hamon, M; Kayser, V | 1 |
| Vaitkus, A; Vilionskis, A | 1 |
| Buzath, A; Lampl, C; Sandor, PS; Yazdi, K | 1 |
| Boutilier, AS; Gardner, DM | 1 |
| Markley, HG | 1 |
| Lempert, T; Neuhauser, H; Radtke, A; von Brevern, M | 1 |
| Stöckli, HR; Sword, A | 1 |
| Adelman, JU; Lewit, EJ | 1 |
| Allen, C; Evans, DC; Evers, R; Hargreaves, R; Lake, BG; O'Connor, D | 1 |
| Becker, WJ; Boes-Hansen, S; Charlesworth, BR; Dowson, AJ; Färkkilä, M; Purdy, A | 2 |
| Ashkenazi, A; Silberstein, SD | 1 |
| Brandes, J; Eikermann, A; MacGregor, EA | 1 |
| Karagounakis, D; Katelanis, S; Spantideas, A; Thomaides, T | 1 |
| Boes, CJ; Goadsby, PJ; Matharu, MS | 1 |
| Diener, HC; Giffin, N; Katsarava, Z; Kaube, H | 1 |
| Gawel, M; Gladstone, JP | 1 |
| Charlesworth, BR; Dowson, AJ | 1 |
| Abu-Shakra, S; Syrett, N; Yates, R | 1 |
| Yao, TW; Yu, LS; Zeng, S | 1 |
| Espinosa Aguilar, MD; Martín-Vivaldi Martínez, R; Nogueras López, F; Redondo Cerezo, E | 1 |
| Diksic, M; Dobson, CF; Hamel, E; Tohyama, Y | 1 |
| Burstein, R; Collins, B; Jakubowski, M | 1 |
| Petro, DJ | 1 |
| Abu-Shakra, S; Loder, E; Mueller, L; Silberstein, SD; Smith, T | 1 |
| Hu, YZ; Wang, XJ; Yao, TW | 1 |
| Diener, HC; MacGregor, EA; Muirheads, N; Schoenen, J; Sikes, CR; Steiner, TJ | 1 |
| Ashcroft, DM; Millson, D | 1 |
| Bigal, ME; Goadsby, PJ; Lipton, RB | 1 |
| Ickenstein, GW; Reuter, U; Salomone, S; Waeber, C | 1 |
| Lines, C; Visser, WH | 1 |
| Baykal, C; Baykal, Y; Cem, B; Yeşim, B | 1 |
| Bravo, MS; Carnero, M; Corredera, E; Escribano, JL; Maciñeiras, JL; Romero, J | 1 |
| Chen, J; Gao, XL; Jiang, WM; Jiang, XG; Mei, N; Zhang, QZ | 1 |
| Jähnichen, S; Pertz, HH; Radtke, OA | 1 |
| Akguen, D; Baykal, O; Diener, HC; Katsarava, Z; Kaube, H; Limmroth, V | 1 |
| Brandes, J; Eikermann, A; Giammarco, R; MacGregor, EA | 1 |
| Bigal, ME; Rapoport, AM; Sheftell, FD; Tepper, SJ | 2 |
| Diener, HC; Evers, S; Gendolla, A | 1 |
| Charlesworth, B; Klapper, J; Lucas, C; Røsjø, Ø | 1 |
| Ni, S; Yao, T; Yu, L; Zeng, S | 1 |
| Airoldi, F; Colombo, A; Mikhail, GW | 1 |
| Brandes, J; Gendolla, A; Giammarco, R; MacGregor, EA | 1 |
| Kato, K | 1 |
| Manaka, S | 1 |
| Kowa, H; Nakashima, K; Takeshima, T | 1 |
| Igarashi, H | 1 |
| Morillo, LE | 2 |
| Li, W; Mao, G; Tian, Y; Xu, F; Zhang, Z | 1 |
| Charlesworth, B; Dodick, DW; Rapoport, AM; Spierings, EL | 1 |
| Gross-Isseroff, R; Hermesh, H; Magen, A; Shiloh, R; Weizman, A | 1 |
| Muñoz, P; Pascual, J | 1 |
| Aschoff, J; Charlesworth, BR; Gawel, M; May, A | 2 |
| Charlesworth, BR; Diener, HC; Dowson, AJ; Färkkilä, M; Gawel, M; Green, J; Hansen, SB | 1 |
| Brandes, J; Dodick, D; Elkind, A; Mathew, N; Rodichok, L | 1 |
| Chandrasekhar, KB; Islam, A; Kumar, PR; Rao, BM; Sridhar, G; Srinivasu, MK | 2 |
| Abu-Shakra, S; Adelman, J; Freitag, FG; Loder, E; Pearlmand, S | 1 |
| De Almeida, RM; Debold, JF; Faccidomo, S; Fish, EW; Miczek, KA | 1 |
| Edvinsson, L; Ingemansson, R; Jarvius, M; Malmsjö, M; Wackenfors, A | 1 |
| Antoni, G; Bergström, M; Frändberg, P; Gustavsson, SA; Jacobsson, E; Kågedal, M; Långström, B; Nilsson, D; Wall, A; Yates, R | 1 |
| Chandrasekhar, KB; Kumar, PR; Rao, BM; Sridhar, G; Srinivasu, MK | 1 |
| Gawel, M; Worthington, I | 1 |
| Capuano, A; Di Trapani, G; Evangelista, M; Ferraro, D; Mei, D; Pierguidi, L; Vollono, C | 1 |
| Lewis, DW; Sowell, M; Winner, P; Yonker, M | 1 |
| Dowson, AJ; Loder, EW; Spierings, EL | 1 |
| Almqvist, P; Dowson, AJ | 1 |
| Diener, HC; Gendolla, A | 1 |
| Deixler, E; Helmke, K | 1 |
| Babbar, AK; Misra, A; Sharma, RK; Vyas, TK | 1 |
| Antoni, G; Bergström, M; Dane, A; Kemp, J; Långström, B; Nairn, K; Sörensen, J; Yates, R | 1 |
| Bergström, M; Kågedal, M; Långström, B; Syvänen, S; Wall, A; Yates, R | 1 |
| Ma, S; Xu, X; Zhang, D | 1 |
| Lewis, D; Rothner, AD; Stankowski, J; Wasiewski, W; Winner, P | 1 |
| Goadsby, PJ; Yates, R | 1 |
| Chen, X; Jin, F; Liu, D; Luan, Y; Zhong, D | 1 |
| Galbut, BH; Galbut, EJ; Kavinsky, CJ; McMullan, PW; Pacheco-Coronado, R; Schaer, GL; Snell, J | 1 |
| Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L | 1 |
| Katayama, Y; Makita, K; Matsuzawa, Y; Morikawa, T | 1 |
| Caminero, AB; Jurado, C; Navarro, A; Pascual, J | 1 |
| Fulton, JA; Hoffman, RS; Kahn, J; Nelson, LS | 1 |
| Araki, N; Isoyama, A; Kinoshita, S; Nakazato, Y; Shimazu, K; Tamura, N | 1 |
| Acuto, G; Allais, G; Benedetto, C; Bussone, G; Cabarrocas, X; Esbri, R | 1 |
| Debus, O; Evers, S; Frese, A; Husstedt, IW; Kraemer, C; Kurlemann, G; Rahmann, A | 1 |
| Kanwar, VS; Pearce, J | 1 |
| Caminero, AB; Díaz-Insa, S; Huerta, M; Jurado, C; Navarro, A; Pascual, J | 1 |
| Bussone, G; Cittadini, E; Evers, S; Goadsby, PJ; May, A; Straube, A | 1 |
| Yao, TW; Yu, LS; Zeng, S; Zhao, NP | 1 |
| Almqvist, P; Dowson, A; Lacoste, JP; Shapero, G | 1 |
| Emeribe, U; Hee, A; Silberstein, S; Tuchman, M | 1 |
| Cunha, L; Dahlöf, CG; Diener, HC; Dowson, AJ; Färkkilä, M; Goadsby, PJ; Manzoni, GC; Massiou, H; Mateos, V; Pascual, J; Raets, I | 1 |
| Diener, HC; Evers, S | 1 |
| Siow, C; Tan, EK | 1 |
| Ziegler, R | 1 |
| Kornblau, DH | 1 |
| Fontes Ribeiro, CA; Marques, FB; Silva, SA | 1 |
| Yu, L; Zeng, S | 1 |
| Krishnan, H; Ravikumar, K; Sridhar, B; Swamy, GY | 1 |
| Buhler, L; Hadaya, K; Malacarne, S; Martin, PY; Moll, S | 1 |
| Hershey, AD; Lewis, DW; Wasiewski, WW; Winner, P | 1 |
| Bigal, ME; Dodick, D; Mathew, NT; Rapoport, AM; Sheftell, FD; Silberstein, SD; Tepper, SJ | 1 |
| Jung, S | 1 |
| Gano, D; Gerretsen, P; Silver, S | 1 |
| Bundy, M; Dowson, A; Kilminster, S; Salt, R | 1 |
| Rosenberg-Nordmann, M; Sprenger, T; Tölle, TR | 1 |
| Peterlin, BL; Rapoport, AM | 1 |
| Ashcroft, DM; Chen, LC | 1 |
| Lin, JP; Wang, HF; Yan, XP; Zhu, YZ | 1 |
| Martino, G; Perkins, MN | 1 |
| Diener, HC; Haas, S; Huber, G; Lampl, C; Rittberger, E | 1 |
| Kalia, YN; Patel, SR; Sharma, A; Zhong, H | 1 |
| Emeribe, U; Hee, A; Silberstein, S; Tuchman, MM | 1 |
| Bai, Y; Liu, H; Pang, N; Zhang, Z | 1 |
| Lu, S; Ni, S; Yao, T; Yu, L; Zeng, S; Zhao, N | 1 |
| Assaid, C; Dodick, DW; Fan, X; Ferrari, MD; Froman, S; Galet, V; Ho, TW; Koppen, H; Kost, J; Leibensperger, H; Lines, C; Winner, PK | 1 |
| Edvinsson, L | 1 |
| Evans, RW; Schürks, M | 1 |
| Matharu, M; Tyagi, A | 1 |
| Nissilä, M | 1 |
| Avital, A; Gross-Isseroff, R; Hermesh, H; Shiloh, R; Stryjer, R; Weizman, A | 1 |
| Xing, F; Yu, LS; Zeng, S | 1 |
| Alhalaweh, A; Andersson, S; Velaga, SP | 1 |
| Jamieson, DG | 1 |
| Iversen, HK; Olesen, J; Tfelt-Hansen, P; Tvedskov, JF | 1 |
| Dodick, DW; Goadsby, PJ; Hedlund, C; Rapoport, AM | 1 |
| Autret-Leca, E; Beau-Salinas, F; Bensouda-Grimaldi, L; Cissoko, H; Jonville-Béra, AP | 1 |
| Dandekar, P; Jain, R; Nabar, S; Patravale, V | 1 |
| Acikel, S; Akdemir, R; Dogan, M; Kilic, H; Sari, M | 1 |
| Edvinsson, L; Hargreaves, RJ; Kane, SA; Lynch, JJ; Regan, CP | 1 |
| Derry, S; Law, S; Moore, RA | 2 |
| Gowin, JL; Lane, SD; Moeller, FG; Swann, AC | 1 |
| Canbaz, D; Uslu, B | 1 |
| Allais, G; Benedetto, C; Bussone, G; Curone, M; Ferrari, MD; Mea, E; Omboni, S; Tullo, V; Zava, D | 1 |
| Chan, KY; Danser, AH; de Vries, R; Edvinsson, L; Eftekhari, S; Garrelds, IM; Hargreaves, RJ; Kane, SA; Kimblad, PO; Lynch, J; Maassenvandenbrink, A; van den Bogaerdt, AJ | 1 |
| Assaid, C; Dodick, DW; Ho, TW; Kost, J; Lines, C | 1 |
| Bourgoin, S; Hamon, M; Kayser, V; Latrémolière, A | 1 |
| Dodick, DW; Ferrari, MD; Ho, TW; Kost, J; Lines, C; Olesen, J | 1 |
| Bayrak, Z; Erol, H; Ozkan, CK; Ozkan, Y; Savaser, A; Tas, C; Tasdemir, U | 1 |
| Allais, G; Benedetto, C; Bussone, G; Omboni, S; Tullo, V; Zava, D | 1 |
| Airaksinen, M; Hoppu, K; Kaukonen, AM; Klaukka, T; Lindkvist, J | 1 |
| Cai, C; Gu, P; He, H; Qi, N; Tang, X; Yu, C; Zhang, W | 1 |
| Cai, C; Gu, P; He, H; Tang, X; Yu, C; Zhang, W | 1 |
| Choi, HK; Moon, C; Ryoo, JP; Subedi, RK | 1 |
| Golwala, H; Lozano, P; Smith, M | 1 |
| Alhalaweh, A; Gavini, E; Rassu, G; Velaga, SP; Vilinska, A | 1 |
| Břicháč, J; Douša, M; Gibala, P; Klecán, O; Mandelová, Z; Pekárek, T; Rádl, S | 1 |
| Mahmoud, AA; Salah, S | 1 |
| Batista, A; Carvalho, S; Ferreira, A; Ferreira, C; Linhares, F; Margato, R; Mateus, P; Moreira, I; Ribeiro, H | 1 |
| Aydogdu, S; Gökaslan, S; Karagöz, A; Kocaoglu, I; Sahin, D; Ucar, Ö | 1 |
| Bertschi, M; Hess, CW; Sturzenegger, M | 1 |
| Allais, G; Benedetto, C; Bussone, G; Colombo, B; Curone, M; Ferrari, MD; Omboni, S; Tullo, V; Zava, D | 1 |
| Liu, J; Zhou, X | 1 |
| Beggiato, S; Cavazzini, A; Dalpiaz, A; Ferraro, L; Gavini, E; Marchetti, N; Pasti, L; Velaga, S | 1 |
| Casolla, B; D'Alonzo, L; Lionetto, L; Martelletti, P; Mastropietri, F; Negro, A; Simmaco, M | 1 |
| Weidmann, P | 1 |
| Goyal, N; Kumari, A; Sharma, N; Sharma, PK | 1 |
| Cabré, F; Canals, M; Cánovas, M; Polonio, F | 1 |
| Alhalaweh, A; Bandiera, P; Beggiato, S; Dalpiaz, A; Ferraro, L; Gavini, E; Giunchedi, P; Marchetti, N; Rassu, G; Velaga, S | 1 |
| Bennett, DJ; D'Amico, JM; Gorassini, MA; Li, Y | 1 |
| Alegre, F; Banales, JM; Barbero, R; Carreño, N; Chang, HC; García, M; Herrero, I; Morán, A; Pérez-Vizcaíno, F; Prieto, J; Quiroga, J; Reboredo, M; Rodríguez-Ortigosa, CM; Sangro, B | 1 |
| Farde, L; Halldin, C; Jučaite, A; Kanes, S; McCarthy, DJ; Nord, M; Stenkrona, P; Varnäs, K | 1 |
| Al Banchaabouchi, M; Bork, P; Campillos, M; Gavin, AC; Gross, C; Jensen, LJ; Kuhn, M | 1 |
| Allais, G; Benedetto, C; Bussone, G; Omboni, S; Pezzola, D; Tullo, V; Zava, D | 1 |
| Allais, G; Barbanti, P; Benedetto, C; Bussone, G; Cortelli, P; Curone, M; Omboni, S; Peccarisi, C; Pezzola, D; Tullo, V; Zava, D | 1 |
| Evers, S | 1 |
| Gangadhara Reddy, K; Madhavi, G; Madhavi, V; Venugopal, N; Vijaya Bhaskar Reddy, A | 1 |
| El-Kadi, AO; Lotfy, HM; Michael, AM; Rezk, MR; Shehata, MA | 1 |
| Chen, S; Rapoport, AM; Reidenbach, F; Tepper, SJ | 1 |
| Hariharakrishnan, V; Ravikumar, K; Sridhar, B | 1 |
| Kaur, G; Kaur, K | 1 |
| Shimizu, T | 1 |
| Kokare, CR; Shiledar, RR; Tagalpallewar, AA | 1 |
| Christie, M; Dubey, R; Martini, LG | 1 |
| Cui, XP; Lin, H; Lin, M; Mu, JS; Ye, JX | 1 |
| Bird, S; Derry, S; Moore, RA | 1 |
| Baudoin, Y; Guilhem, K; Meyrat, L; Thouard, H | 1 |
| Best, C; Birklein, F; Döring, K; Krämer, HH | 1 |
| Kitagawa, Y; Suzuki, Y; Takayanagi, R; Tokuoka, K; Watanabe, M; Yamada, Y | 1 |
| Garg, T; Goyal, AK; Kumar, A; Rath, G; Sarma, GS | 1 |
| Fang, L; Liu, C | 1 |
| Evers, S; Lisotto, C; Omboni, S; Pinessi, L; Savi, L; Zanchin, G | 1 |
| Abdelmalak, NS; Basalious, EB; El-Setouhy, DA | 1 |
| Behar, T; Böge, B; Galanaud, JP; Laroche, JP; Menjot, N; Quéré, I | 1 |
| Desai, N; Jangid, AG; Mistri, HN; Patel, B; Suhagia, BN | 1 |
| Antle, MC; Baskerville, JD; Basu, P; Ie, N; Smith, VM; Wensel, AL | 1 |
| Girotra, P; Kumar, G; Singh, SK | 1 |
| McKeage, K | 1 |
| Dhamecha, D; Jalalpure, S; Shahi, S; Shelke, S | 1 |
| Srinivas, NR; Syed, M | 1 |
| Abd-Elal, RM; Bendas, ER; Rashed, HM; Shamma, RN | 1 |
| Farkas, V; Lillieborg, S; Liss, C; Raines, S; Štillová, H; Winner, P; Woodruff, B | 1 |
| Anttonen, O; Ekström, K; Lönnberg, A | 1 |
| Heckman, CJ; Thaweerattanasinp, T; Tysseling, VM | 1 |
| Dogra, Y; Khan, T; Misra, A; Pandya, SM; Ranjan, R; Shafi, H; Singh, SK; Yadav, PN | 1 |
| Han, W; Li, M; Wang, J; Xu, H | 1 |
| Carlsen, EM; Rasmussen, R | 1 |
| Isildak, H; O'Connell Ferster, AP; Priesol, AJ | 1 |
| Cotter, AR; Garcia, R; Leslie, K; Neisewander, JL; Olive, MF | 1 |
| Baradia, D; Dobaria, N; Ghoghari, A; Laddha, R; Mehta, P; Modi, N; Patel, H; Patel, P; Shah, S; Srinivas, NR; Variya, B | 1 |
| Al-Huniti, N; Birmingham, B; Li, J; Lillieborg, S; Xu, H; Zhou, D; Zhou, W | 1 |
| Abdou, EM; Kandil, SM; Miniawy, HMFE | 1 |
| Ameri, M; Kellerman, DJ; Tepper, SJ | 1 |
| Lee, JTL; Lin, ML; Skalicky, SE | 1 |
| Brandes, JL; Kellerman, DJ; Kudrow, DB; Schmidt, PC; Spierings, EL; Tepper, SJ; Weintraub, J | 1 |
| Chaudhari, AM; Gandhi, AK; Maheriya, P; Prajapati, VD | 1 |
| Dudhipala, N; Narala, A; Pitta, SK; Veerabrahma, K | 1 |
| Chaudhari, PR; Mandlik, SK; Mohanty, BS; Ranpise, NS | 1 |
| Fang, L; Liu, C; Luo, Z; Wan, X | 1 |
| Ameri, M; Diep, AN; Hochart, G; Lewis, H; Nguyen, J; Queja, A | 1 |
| Dodick, DW; Friedman, DI; Gelfand, AA; Kellerman, DJ; Schmidt, PC; Tepper, SJ | 1 |
| Han, K; Lu, SJ; Yu, LS; Zeng, S | 1 |
| Kusuhara, H; Mizuno, T; Mochizuki, T; Sano, Y; Terasaki, T; Uchida, Y; Umetsu, M | 1 |
| Afzal, A; Agha, F; Ahmad, S; Batool, Z; Haider, S; Liaquat, L; Nawaz, A; Sadir, S; Tabassum, S | 1 |
| Dodick, DW; Kellerman, DJ; Schmidt, PC; Tepper, SJ | 1 |
| Cutler, H; Gauld, N; Gumbie, M; Haywood, P; Mumford, V; Parkinson, B | 1 |
| Fang, L; Liu, C; Quan, P; Ruan, J; Wan, X | 1 |
| Bhadauria, AS; Bhattachariya, B; Chakraborti, S; Gosipatala, SB; Kumar R, V; Kumar, D; Kumar, P; Kumar, U; Maity, B; Maurya, V; Pramanik, A; Saha, B; Saha, S; Singh, AK | 1 |
| Bukka, R; Khezri, FANZ; Lakshmi, CSR; Nargund, SL; Nidhi, M | 1 |
| Abdou, EM | 1 |
| El-Nabarawy, NA; Helal, DA; Teaima, MH | 1 |
| Barricklow, J; Holliman, CL; Ramanathan, R; Tweed, J | 1 |
| Bennett, DJ; Birch, D; Heckman, CJ; Jiang, MC; Thaweerattanasinp, T; Tresch, MC; Tysseling, VM | 1 |
| Ameri, M; Kellerman, DJ; Lewis, H; Rapoport, AM | 1 |
| Awadeen, RH; Boughdady, MF; Meshali, MM | 1 |
| Courault, P; Demarquay, G; Lancelot, S; Zimmer, L | 1 |
| Amundsen, S; Fuskevåg, OM; Nordeng, H; Nordmo, E; Sager, G; Spigset, O | 1 |
| Amann, TK; Drescher, J; Gaul, C; Khouri, A; Kropp, P; Scheidt, J; Siebenhaar, Y | 1 |
| Elbuluk, N; Foreman, PK; Friedman, DI; Hindiyeh, N; Kellerman, DJ; Nahas, SJ; Schmidt, P | 1 |
| Han, L; Jia, Y; Peng, Y; Sun, C; Zhao, M; Zhao, Y; Zheng, J | 1 |
| Fang, L; Liu, C; Luo, Z; Quan, P; Zhang, Y | 1 |
| Bansod, P; Swathi, KP; Tripathi, AS | 1 |
| Abd El-Halim, SM; Aly Labib, DA; Eid, SM; Ibrahim, BMM; Mamdouh, MA; Soliman, SM | 1 |
| Diener, HC; May, A | 1 |
| Jha, S; Mishra, D | 1 |
| Abo El Abass, S; Abo Zaid, MH; Aly, F; El-Enany, N | 1 |
| Christensen, KV; Fryland, T; Hansen, JB; Mikkelsen, JD; Stoica, A; Thomsen, M | 1 |
| Ali Shah, K; Cui, JH; Gao, B; Huang, L; Iqbal, H; Kamal, R; Lina, S; Ning Zhu, Q; Razzaq, A; Ullah Khan, N | 1 |
| Duan, S; Li, G; Liu, L; Liu, Z; Ren, Z; Wang, Z; Xia, H; Zhu, T | 1 |
80 review(s) available for oxazolidin-2-one and zolmitriptan
| Article | Year |
|---|---|
The clinical effectiveness of 311C90 in the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Multicenter Studies as Topic; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Clinical safety of 311C90: aggregated data from patients and volunteers to date.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
Inhibition of the trigemino-vascular system with 5-HT1D agonist drugs: selectively targeting additional sites of action.
Topics: Administration, Oral; Biological Availability; Cerebrovascular Circulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
Emerging preclinical and clinical profile of 311C90: a poster review and discussion.
Topics: Animals; Central Nervous System; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Tryptamines | 1996 |
Increasing the options for effective migraine management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Ergotamine; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
311C90: increasing the options for therapy with effective acute antimigraine 5HT1B/1D receptor agonists.
Topics: Headache; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Zolmitriptan. Introduction.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1997 |
Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine.
Topics: Administration, Oral; Animals; Biological Availability; Drug Evaluation, Preclinical; Hemodynamics; Injections, Intravenous; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Potential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90).
Topics: Acetaminophen; Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Ergotamine; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 1997 |
Clinical applications of zolmitriptan (Zomig, 311C90).
Topics: Acute Disease; Disabled Persons; Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Mechanism of action of zolmitriptan].
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
[Clinical efficacy of zolmitriptan in migraine].
Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
[Safety profile of 311C90 (zolmitriptan)].
Topics: Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.
Topics: Acute Disease; Animals; Clinical Trials as Topic; Coronary Circulation; Coronary Vasospasm; Drug Design; Drug Interactions; Humans; Inactivation, Metabolic; Indoles; Meninges; Migraine Disorders; Molecular Structure; Nociceptors; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Pyrrolidines; Randomized Controlled Trials as Topic; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Recurrence; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents | 1999 |
Zolmitriptan: a review of its use in migraine.
Topics: Age Factors; Clinical Trials as Topic; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Acute management of migraine: triptans and beyond.
Topics: Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
[Zolmitriptan].
Topics: Drug Costs; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Selection; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1999 |
The scientific basis of medication choice in symptomatic migraine treatment.
Topics: Acute Disease; Choice Behavior; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Triazoles; Tryptamines | 1999 |
Newer intranasal migraine medications.
Topics: Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Clinical Trials as Topic; Dihydroergotamine; Half-Life; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2000 |
How effective are triptans in the treatment of episodic and chronic cluster headache.
Topics: Chronic Disease; Cluster Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Current and emerging second-generation triptans in acute migraine therapy: a comparative review.
Topics: Acute Disease; Carbazoles; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2000 |
[Emergency treatment of migraine attacks with particular reference to agonists of 5-HT1B/1D receptor].
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Emergency Treatment; Ergotamine; Humans; Migraine Disorders; Nausea; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
New abortive agents for the treatment of migraine.
Topics: Clinical Trials as Topic; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prognosis; Recurrence; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2001 |
Recent development in paediatric headache.
Topics: Adolescent; Analgesics; Child; Clinical Trials as Topic; Diagnosis, Differential; Headache; Humans; Oxazolidinones; Prognosis; Sumatriptan; Tryptamines | 2001 |
[Current topics: expectation for new triptans].
Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).
Topics: Analgesics, Non-Narcotic; Carbazoles; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Triazoles; Tryptamines | 2001 |
Have the triptans fulfilled their promise?
Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Triptans are all different.
Topics: Carbazoles; Headache; Humans; Indoles; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
What matters is not the differences between triptans, but the differences between patients.
Topics: Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Comparison of rizatriptan and other triptans on stringent measures of efficacy.
Topics: Administration, Oral; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Acute treatment of migraine and the role of triptans.
Topics: Acute Disease; Blood Flow Velocity; Carbazoles; Clinical Trials as Topic; Drug Administration Routes; Female; Humans; Indoles; Male; Menstruation; Migraine Disorders; Oxazolidinones; Piperidines; Practice Guidelines as Topic; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Review of zolmitriptan and its clinical applications in migraine.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Interactions; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 2002 |
Mechanisms of action of the 5-HT1B/1D receptor agonists.
Topics: Carbazoles; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2002 |
[Treatment of migraine in patients with hypertension and ischemic heart disease].
Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Contraindications; Dihydroergotamine; Dopamine Agonists; Ergotamine; Humans; Hypertension; Indoles; Migraine Disorders; Myocardial Ischemia; Oxazolidinones; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2002 |
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
Topics: Adaptation, Psychological; Aggression; Animals; Brain; Dopamine; Ethanol; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, Dopamine; Receptors, GABA; Receptors, Serotonin; Reinforcement Schedule; Serotonin; Serotonin Receptor Agonists; Social Environment; Tryptamines | 2002 |
Zolmitriptan: differences from sumatriptan.
Topics: Cluster Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
[The problems of migraine headache treatment].
Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Aspirin; Dihydroergotamine; Female; Humans; Male; Methysergide; Migraine Disorders; Oxazolidinones; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Sumatriptan; Time Factors; Tryptamines; Vasoconstrictor Agents | 2002 |
Reassessing the contraindication of zolmitriptan and serotonin reuptake inhibitors: an evidence-based pharmacotherapeutic case report.
Topics: Contraindications; Depression; Drug Interactions; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Serotonin Syndrome; Tryptamines | 2003 |
Topical agents in the treatment of cluster headache.
Topics: Administration, Intranasal; Administration, Topical; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Humans; Lidocaine; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 2003 |
Comparative aspects of triptans in treating migraine.
Topics: Carbazoles; Cardiovascular Diseases; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2001 |
The evolving management of migraine.
Topics: Angiotensin Receptor Antagonists; Anticonvulsants; Antipsychotic Agents; Botulinum Toxins, Type A; Carbazoles; Droperidol; Fructose; Humans; Indoles; Migraine Disorders; Neuromuscular Agents; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Topiramate; Tryptamines | 2003 |
Management of trigeminal autonomic cephalgias and hemicrania continua.
Topics: Analgesics; Anesthetics, Local; Drug Administration Schedule; Ergot Alkaloids; Female; Humans; Male; Oxazolidinones; Oxygen; Sumatriptan; Trigeminal Neuralgia; Tryptamines; Vascular Headaches | 2003 |
Newer formulations of the triptans: advances in migraine management.
Topics: Analgesics; Area Under Curve; Chemistry, Pharmaceutical; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines | 2003 |
Clinical applications of new therapeutic deliveries in migraine.
Topics: Administration, Intranasal; Administration, Oral; Adult; Clinical Trials as Topic; Dysgeusia; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Migraine Disorders; Nausea; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tryptamines; Vasoconstrictor Agents | 2003 |
Naratriptan for the treatment of acute migraine: meta-analysis of randomised controlled trials.
Topics: Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Double-blind clinical trials of oral triptans vs other classes of acute migraine medication - a review.
Topics: Administration, Oral; Analgesics; Double-Blind Method; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Randomized Controlled Trials as Topic; Sumatriptan; Tryptamines | 2004 |
Intranasal medications for the treatment of migraine and cluster headache.
Topics: Administration, Intranasal; Analgesics; Capsaicin; Cluster Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Triptans in migraine: a comparative review of pharmacology, pharmacokinetics].
Topics: Animals; Biological Availability; Cardiovascular System; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Triptans in migraine: from clinical view].
Topics: Drug Administration Schedule; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Meta-analysis of triptan treatment in migraine].
Topics: Carbazoles; Evidence-Based Medicine; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
[Side effects of triptans].
Topics: Central Nervous System; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Nausea; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sleep Stages; Sumatriptan; Triazoles; Tryptamines; Vomiting | 2004 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
Zolmitriptan (Zomig).
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Intranasal zolmitriptan.
Topics: Administration, Intranasal; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2005 |
The treatment of pediatric migraine.
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Antidepressive Agents; Antiemetics; Biofeedback, Psychology; Calcium Channel Blockers; Child; Complementary Therapies; Contraindications; Cyproheptadine; Diet; Ergot Alkaloids; Humans; Migraine Disorders; Migraine without Aura; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2005 |
Part III: the convenience of, and patient preference for, zolmitriptan orally disintegrating tablet.
Topics: Chemistry, Pharmaceutical; Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Tablets; Therapeutic Equivalency; Tryptamines | 2005 |
Zolmitriptan intranasal: a review of the pharmacokinetics and clinical efficacy.
Topics: Administration, Intranasal; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 2006 |
Myocardial infarction after taking zolmitriptan.
Topics: Aged; Coronary Artery Disease; Female; Humans; Migraine Disorders; Myocardial Infarction; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2005 |
Acute treatment of paediatric migraine: a meta-analysis of efficacy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Dihydroergotamine; Drug Evaluation; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Placebos; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2008 |
[Trigeminal autonomic cephalgias: diagnostic and therapeutic implications].
Topics: Administration, Intranasal; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cluster Headache; Diagnosis, Differential; Humans; Indomethacin; Injections, Subcutaneous; Magnetic Resonance Imaging; Oxazolidinones; Paroxysmal Hemicrania; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Time Factors; Trigeminal Autonomic Cephalalgias; Tryptamines; Vasodilator Agents; Verapamil | 2007 |
Clinical pharmacology of the serotonin receptor agonist, zolmitriptan.
Topics: Clinical Trials as Topic; Humans; Migraine Disorders; Models, Biological; Molecular Structure; Oxazolidinones; Pharmacology, Clinical; Serotonin; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2007 |
Meta-analysis of the efficacy and safety of zolmitriptan in the acute treatment of migraine.
Topics: Adolescent; Adult; Age Factors; Aged; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 2008 |
Evidence base for the medical treatments used in cluster headache.
Topics: Cluster Headache; Evidence-Based Medicine; Humans; Nerve Block; Octreotide; Oxazolidinones; Oxygen; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2009 |
Zolmitriptan nasal spray in the acute treatment of cluster headache: a meta-analysis of two studies.
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Cluster Headache; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazolidinones; Placebo Effect; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Young Adult | 2009 |
Triptans for acute cluster headache.
Topics: Cluster Headache; Humans; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2010 |
Efficacy of frovatriptan and other triptans in the treatment of acute migraine of hypertensive and normotensive subjects: a review of randomized studies.
Topics: Carbazoles; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2013 |
The efficacy of triptans in childhood and adolescence migraine.
Topics: Adolescent; Analgesics; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Germany; Humans; Male; Migraine Disorders; Oxazolidinones; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2013 |
Intranasal zolmitriptan for the treatment of acute migraine.
Topics: Administration, Intranasal; Animals; Clinical Trials as Topic; Humans; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Tryptamines | 2013 |
[New treatments for cluster headache].
Topics: Administration, Intranasal; Calcium Channel Blockers; Cluster Headache; Deep Brain Stimulation; Dexamethasone; Humans; Injections, Subcutaneous; Methylprednisolone; Nerve Block; Oxazolidinones; Oxygen Inhalation Therapy; Sumatriptan; Tryptamines; Vagus Nerve Stimulation; Verapamil | 2013 |
Triptans for acute cluster headache.
Topics: Cluster Headache; Humans; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2013 |
Efficacy, safety, and tolerability of telcagepant in the treatment of acute migraine: a meta-analysis.
Topics: Acute Disease; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines | 2015 |
Zolmitriptan for acute migraine attacks in adults.
Topics: Acute Pain; Administration, Oral; Adult; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin 5-HT1 Receptor Agonists; Time Factors; Tryptamines | 2014 |
Efficacy of frovatriptan as compared to other triptans in migraine with aura.
Topics: Adult; Carbazoles; Female; Humans; Male; Middle Aged; Migraine with Aura; Oxazolidinones; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles; Tryptamines | 2015 |
Zolmitriptan Nasal Spray: A Review in Acute Migraine in Pediatric Patients 12 Years of Age or Older.
Topics: Administration, Intranasal; Child; Humans; Migraine Disorders; Nasal Sprays; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; United States | 2016 |
Network meta-analysis of migraine disorder treatment by NSAIDs and triptans.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Pyrrolidines; Randomized Controlled Trials as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2016 |
The clinical manifestations of vestibular migraine: A review.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Dizziness; Headache; Humans; Migraine Disorders; Oxazolidinones; Quality of Life; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Vertigo; Vestibular Diseases | 2017 |
Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives.
Topics: Antibodies, Monoclonal; Botulinum Toxins, Type A; Capsaicin; Carbon Dioxide; Clinical Trials as Topic; Cluster Headache; Humans; Ketamine; Lysergic Acid Diethylamide; Oxazolidinones; Psilocybin; Receptors, Calcitonin Gene-Related Peptide; Somatostatin; Tryptamines | 2021 |
Drug Treatment of Cluster Headache.
Topics: Cluster Headache; Drug Administration Routes; Humans; Lithium; Oxazolidinones; Oxygen Inhalation Therapy; Prednisolone; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Tryptamines; Verapamil | 2022 |
Efficacy and safety of intranasal agents for the acute treatment of migraine: a systematic review and network meta-analysis.
Topics: Adult; Humans; Migraine Disorders; Nasal Sprays; Network Meta-Analysis; Oxazolidinones | 2023 |
109 trial(s) available for oxazolidin-2-one and zolmitriptan
| Article | Year |
|---|---|
311C90, a new central and peripherally acting 5-HT1D receptor agonist in the acute oral treatment of migraine: a double-blind, placebo-controlled, dose-range finding study.
Topics: Administration, Oral; Adolescent; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Pain Measurement; Placebos; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1996 |
Evaluation of the long-term safety and efficacy of 311C90 in the treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Child; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Can oral 311C90, a novel 5-HT1D agonist, prevent migraine headache when taken during an aura?
Topics: Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; United Kingdom | 1996 |
The tolerability and pharmacokinetics of the novel antimigraine compound 311C90 in healthy male volunteers.
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
311C90: long-term efficacy and tolerability profile for the acute treatment of migraine. International 311C90 Long-Term Study Group.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Research Design; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90) in healthy volunteers.
Topics: Administration, Oral; Adult; Analysis of Variance; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Zolmitriptan: new perspectives in migraine therapy. Satellite symposium of the 11th Migraine Trust International Symposium, London, 10 September 1996].
Topics: Blood-Brain Barrier; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Sumatriptan; Tryptamines | 1997 |
The absolute bioavailability and metabolic disposition of the novel antimigraine compound zolmitriptan (311C90).
Topics: Absorption; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Feces; Female; Half-Life; Humans; Indoleacetic Acids; Infusions, Intravenous; Male; Mass Spectrometry; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sex Factors; Tryptamines | 1997 |
Peripheral vascular effects and pharmacokinetics of the antimigraine compound, zolmitriptan, in combination with oral ergotamine in healthy volunteers.
Topics: Administration, Oral; Adult; Biological Availability; Blood Pressure; Caffeine; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Ergotamine; Female; Humans; Intestinal Absorption; Male; Oxazoles; Oxazolidinones; Pulse; Reference Values; Serotonin Receptor Agonists; Tryptamines; Vasoconstrictor Agents | 1997 |
Optimizing the dose of zolmitriptan (Zomig, 311C90) for the acute treatment of migraine. A multicenter, double-blind, placebo-controlled, dose range-finding study. The 017 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
Clinical efficacy and tolerability of 2.5 mg zolmitriptan for the acute treatment of migraine. The 042 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Zolmitriptan (Zomig, 311C90), a novel dual central and peripheral 5HT1B/1D agonist: an overview of efficacy.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Female; Humans; Menstruation; Middle Aged; Migraine Disorders; Nausea; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
Tolerability profile of zolmitriptan (Zomig; 311C90), a novel dual central and peripherally acting 5HT1B/1D agonist. International clinical experience based on > 3000 subjects treated with zolmitriptan.
Topics: Administration, Oral; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Cardiovascular System; Child; Humans; Incidence; Middle Aged; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
No need to adjust the dose of 311C90 (zolmitriptan), a novel anti-migraine treatment, in patients with renal failure not requiring dialysis.
Topics: Adult; Aged; Area Under Curve; Blood Pressure; Electrocardiography; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Renal Dialysis; Serotonin Receptor Agonists; Tryptamines | 1997 |
The interaction between propranolol and the novel antimigraine agent zolmitriptan (311C90).
Topics: Adrenergic beta-Antagonists; Adult; Area Under Curve; Biotransformation; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Electrocardiography; Female; Half-Life; Humans; Male; Oxazoles; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Tryptamines | 1997 |
Intensity dependence of the cortical auditory evoked potentials as a surrogate marker of central nervous system serotonin transmission in man: demonstration of a central effect for the 5HT1B/1D agonist zolmitriptan (311C90, Zomig).
Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1997 |
The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide.
Topics: Acetaminophen; Adult; Blood Pressure; Drug Interactions; Female; Humans; Male; Metoclopramide; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The pharmacodynamics and pharmacokinetics of the 5HT1B/1D-agonist zolmitriptan in healthy young and elderly men and women.
Topics: Adult; Age Factors; Aged; Blood Pressure; Central Nervous System; Double-Blind Method; Electrocardiography; Female; Half-Life; Heart Rate; Humans; Male; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Sex Factors; Tryptamines | 1998 |
The long-term tolerability and efficacy of oral zolmitriptan (Zomig, 311C90) in the acute treatment of migraine. An international study. The International 311C90 Long-term Study Group.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1998 |
Zolmitriptan (311C90) does not interact with fluoxetine in healthy volunteers.
Topics: Adolescent; Adult; Cranial Sinuses; Cross-Over Studies; Dizziness; Drug Interactions; Drug Tolerance; Female; Fluoxetine; Humans; Intracranial Pressure; Male; Middle Aged; Nausea; Oxazoles; Oxazolidinones; Patient Compliance; Pharyngitis; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines | 1998 |
Pharmacokinetics and pharmacodynamics of zolmitriptan in patients with mild to moderate hypertension: a double-blind, placebo-controlled study.
Topics: Area Under Curve; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sodium Chloride Symporter Inhibitors; Tryptamines | 1998 |
Effect of hepatic impairment on the pharmacokinetics of zolmitriptan.
Topics: Adult; Aged; Area Under Curve; Biotransformation; Blood Pressure; Female; Half-Life; Humans; Liver Diseases; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Effects of the antimigraine compound zolmitriptan ('Zomig') on psychomotor performance alone and in combination with diazepam in healthy volunteers.
Topics: Adult; Cross-Over Studies; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxazoles; Oxazolidinones; Psychometrics; Psychomotor Performance; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1998 |
The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers.
Topics: Adolescent; Adult; Biological Availability; Cross-Over Studies; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Lack of an effect of zolmitriptan (Zomig, 311C90) on psychometric task performance: results of a placebo-controlled study in healthy volunteers.
Topics: Adolescent; Adult; Affect; Anti-Anxiety Agents; Color Perception; Cross-Over Studies; Double-Blind Method; Female; Humans; Lorazepam; Male; Mental Processes; Middle Aged; Oxazoles; Oxazolidinones; Psychometrics; Psychomotor Performance; Reaction Time; Serotonin Receptor Agonists; Tryptamines | 1998 |
Effects of zolmitriptan (Zomig) on central serotonergic neurotransmission as assessed by active oddball auditory event-related potentials in volunteers without migraine.
Topics: Acoustic Stimulation; Adult; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1999 |
A comparison of the pharmacokinetics and tolerability of the novel antimigraine compound zolmitriptan in adolescents and adults.
Topics: Adolescent; Adult; Aged; Aging; Area Under Curve; Biotransformation; Child; Female; Half-Life; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1999 |
The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers.
Topics: Adult; Area Under Curve; Benzamides; Biotransformation; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 1999 |
Zolmitriptan-induced growth hormone release in humans: mediation by 5-HT1D receptors?
Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Female; Human Growth Hormone; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Unbalanced randomization influences placebo response: scientific versus ethical issues around the use of placebo in migraine trials.
Topics: Double-Blind Method; Ethics, Medical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1999 |
A long-term study to maximise migraine relief with zolmitriptan.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 1999 |
Zolmitriptan provides consistent migraine relief when used in the long-term.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Zolmitriptan is effective for the treatment of persistent and recurrent migraine headache.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
[Oral zolmitriptan (Zomig) in the treatment of migraine crisis].
Topics: Administration, Oral; Adolescent; Adult; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2000 |
A comparative trial of zolmitriptan and sumatriptan for the acute oral treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Satisfaction; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2000 |
Oral zolmitriptan is effective in the acute treatment of cluster headache.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Cluster Headache; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Pain Measurement; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2000 |
Comparison of the efficacy of zolmitriptan and sumatriptan: issues in migraine trial design.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2000 |
Low dose zolmitriptan as a 5-HT neuroendocrine challenge agent in humans.
Topics: Adult; Blood Pressure; Body Temperature; Double-Blind Method; Female; Human Growth Hormone; Humans; Hydrocortisone; Kinetics; Male; Neurosecretory Systems; Oxazoles; Oxazolidinones; Placebos; Prolactin; Serotonin Receptor Agonists; Tryptamines | 2000 |
Treatment of nonresponders to oral sumatriptan with zolmitriptan and rizatriptan: a comparative open trial.
Topics: Administration, Oral; Cross-Over Studies; Drug Resistance; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Retreatment; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Comparison of rizatriptan 10 mg vs. zolmitriptan 2.5 mg in the acute treatment of migraine. Rizatriptan-Zolmitriptan Study Group.
Topics: Adult; Disability Evaluation; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Quality of Life; Recurrence; Retreatment; Serotonin Receptor Agonists; Time Factors; Triazoles; Tryptamines | 2000 |
Zolmitriptan (a 5-HT1B/1D receptor agonist with central action) does not increase symptoms in obsessive compulsive disorder.
Topics: Adult; Behavior; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 2000 |
Vascular effects of 5-HT1B/1D-receptor agonists in patients with migraine headaches.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Artery, Common; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Temporal Arteries; Triazoles; Tryptamines; Ultrasonography; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 2000 |
Zolmitriptan provides effective migraine relief in adolescents.
Topics: Acute Disease; Adolescent; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Measurement; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2000 |
Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; International Cooperation; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Treatment Outcome; Tryptamines | 2001 |
Clinical features of withdrawal headache following overuse of triptans and other headache drugs.
Topics: Adult; Analgesics; Drug Therapy, Combination; Ergotamine; Female; Headache; Humans; Indoles; Male; Middle Aged; Oxazolidinones; Piperidines; Prospective Studies; Substance Withdrawal Syndrome; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2001 |
Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2002 |
Cost-effectiveness analysis of stratified versus stepped care strategies for acute treatment of migraine: The Disability in Strategies for Care (DISC) Study.
Topics: Cost-Benefit Analysis; Disability Evaluation; Drug Costs; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2002 |
Acute migraine headache: possible sensitization of neurons in the spinal trigeminal nucleus?
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Blinking; Electroencephalography; Electrophysiology; Female; Humans; Male; Middle Aged; Migraine Disorders; Nerve Fibers; Neurons; Nociceptors; Oxazolidinones; Trigeminal Nucleus, Spinal; Tryptamines | 2002 |
Zolmitriptan orally disintegrating tablet is effective in the acute treatment of migraine.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Palliative Care; Patient Satisfaction; Recurrence; Retreatment; Serotonin Receptor Agonists; Solubility; Tryptamines | 2002 |
Zolmitriptan is effective and well tolerated in Japanese patients with migraine: a dose-response study.
Topics: Adult; Cultural Characteristics; Dose-Response Relationship, Drug; Female; Humans; Hyperacusis; Japan; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Photophobia; Recurrence; Safety; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Vomiting | 2002 |
The pharmacokinetics of the antimigraine compound zolmitriptan in Japanese and Caucasian subjects.
Topics: Administration, Oral; Adult; Area Under Curve; Asian People; Female; Humans; Japan; Male; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Smoking; Tryptamines; White People | 2002 |
Preliminary studies of the pharmacokinetics and tolerability of zolmitriptan nasal spray in healthy volunteers.
Topics: Administration, Intranasal; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Male; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 2002 |
Pharmacokinetics, dose proportionality, and tolerability of single and repeat doses of a nasal spray formulation of zolmitriptan in healthy volunteers.
Topics: Administration, Intranasal; Adult; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 2002 |
Zolmitriptan for treatment of migrainous vertigo: a pilot randomized placebo-controlled trial.
Topics: Administration, Oral; Adult; Aged; Cross-Over Studies; Double-Blind Method; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines; Vertigo | 2003 |
[Zolmitriptan as fast-melt tablet in the acute treatment of patients with migraine attacks: the ZORO study].
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Prospective Studies; Recurrence; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 2003 |
Speed of onset and efficacy of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled, dose-ranging study versus zolmitriptan tablet.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Time Factors; Tryptamines | 2003 |
Tolerability and consistency of effect of zolmitriptan nasal spray in a long-term migraine treatment trial.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2003 |
Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cross-Over Studies; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tablets; Treatment Outcome; Tryptamines | 2003 |
Zolmitriptan nasal spray: advances in migraine treatment.
Topics: Absorption; Administration, Intranasal; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Nasal Decongestants; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Vasoconstrictor Agents | 2003 |
Efficacy and tolerability of oral zolmitriptan in menstrually associated migraine: a randomized, prospective, parallel-group, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Double-Blind Method; Female; Follow-Up Studies; Humans; Menstruation; Middle Aged; Migraine Disorders; Oxazolidinones; Prospective Studies; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Indoles; Linear Models; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pyrrolidines; Tryptamines | 2003 |
Differences of anti-nociceptive mechanisms of migraine drugs on the trigeminal pain processing during and outside acute migraine attacks.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blinking; Electrophysiology; Female; Humans; Male; Migraine without Aura; Oxazolidinones; Pain; Pain Measurement; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 2004 |
Benefits of treating highly disabled migraine patients with zolmitriptan while pain is mild.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Confidence Intervals; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Migraine Disorders; Odds Ratio; Oxazolidinones; Pain; Prospective Studies; Time Factors; Tryptamines | 2004 |
Migraine treatment strategies: the global Migraine And Zolmitriptan Evaluation (MAZE) survey--phase IV.
Topics: Adult; Drug Prescriptions; Female; Humans; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Patient Satisfaction; Patients; Serotonin Receptor Agonists; Surveys and Questionnaires; Tryptamines; United Kingdom | 2004 |
Acute treatment of migraine with zolmitriptan 5 mg orally disintegrating tablet.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Double-Blind Method; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Time Factors; Treatment Outcome; Tryptamines | 2004 |
The 5-HT1D receptor agonist zolmitriptan for neuroleptic-induced akathisia: an open label preliminary study.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Humans; Male; Middle Aged; Oxazolidinones; Psychiatric Status Rating Scales; Schizophrenia; Serotonin; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Zolmitriptan 5 mg nasal spray: efficacy and onset of action in the acute treatment of migraine--results from phase 1 of the REALIZE Study.
Topics: Acute Disease; Administration, Intranasal; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Zolmitriptan nasal spray exhibits good long-term safety and tolerability in migraine: results of the INDEX trial.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Speed of onset, efficacy and tolerability of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled study.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Reaction Time; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Pain-free rates with zolmitriptan 2.5 mg ODT in the acute treatment of migraine: results of a large double-blind placebo- controlled trial.
Topics: Acute Disease; Administration, Oral; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain; Placebos; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Distribution of zolmitriptan into the CNS in healthy volunteers: a positron emission tomography study.
Topics: Administration, Intranasal; Adolescent; Adult; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Female; Humans; Male; Models, Biological; Oxazolidinones; Positron-Emission Tomography; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 2005 |
Multiple attack study on the available triptans in Italy versus placebo.
Topics: Adult; Female; Humans; Indoles; Italy; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
Distribution of intranasal C-zolmitriptan assessed by positron emission tomography.
Topics: Administration, Inhalation; Adolescent; Adult; Brain; Carbon Radioisotopes; Female; Humans; Male; Metabolic Clearance Rate; Nasal Mucosa; Nasopharynx; Nose; Organ Specificity; Oxazolidinones; Positron-Emission Tomography; Radiopharmaceuticals; Respiratory Mucosa; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 2005 |
Treatment satisfaction with zolmitriptan nasal spray for migraine in a real life setting: results from phase two of the REALIZE study.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Humans; Male; Middle Aged; Migraine Disorders; Nasal Cavity; Oxazolidinones; Pain Measurement; Patient Satisfaction; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Zolmitriptan oral tablet in migraine treatment: high placebo responses in adolescents.
Topics: Adolescent; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Measurement; Placebo Effect; Serotonin Receptor Agonists; Tryptamines | 2006 |
[Experience with intranasal zolmitriptan in cluster headache].
Topics: Administration, Intranasal; Adult; Aged; Cluster Headache; Female; Humans; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2006 |
Efficacy and tolerability of almotriptan versus zolmitriptan for the acute treatment of menstrual migraine.
Topics: Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2006 |
Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.
Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Female; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2006 |
[Symptomatic treatment of migraine with zolmitriptan: experience with 82 patients].
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2006 |
Effectiveness of intranasal zolmitriptan in acute cluster headache: a randomized, placebo-controlled, double-blind crossover study.
Topics: Acute Disease; Administration, Intranasal; Adolescent; Adult; Aged; Cluster Headache; Cohort Studies; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2006 |
Efficacy and tolerability of zolmitriptan oral tablet in the acute treatment of menstrual migraine.
Topics: Acute Disease; Administration, Oral; Adult; Chest Pain; Dizziness; Double-Blind Method; Female; Humans; Menstruation Disturbances; Middle Aged; Migraine Disorders; Nausea; Oxazolidinones; Paresthesia; Patient Dropouts; Self Administration; Serotonin Receptor Agonists; Tablets; Treatment Outcome; Tryptamines | 2006 |
Almotriptan and zolmitriptan in the acute treatment of migraine.
Topics: Acute Disease; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2007 |
Effectiveness and satisfaction with zolmitriptan 5 mg nasal spray for treatment of migraine in real-life practice: results of a postmarketing surveillance study.
Topics: Administration, Intranasal; Adult; Adverse Drug Reaction Reporting Systems; Cardiovascular Diseases; Dizziness; Female; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Nausea; Oxazolidinones; Patient Satisfaction; Product Surveillance, Postmarketing; Serotonin Receptor Agonists; Surveys and Questionnaires; Treatment Outcome; Tryptamines | 2007 |
Efficacy of zolmitriptan nasal spray in adolescent migraine.
Topics: Administration, Intranasal; Adolescent; Child; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Single-Blind Method; Time Factors; Tryptamines | 2007 |
Zolmitriptan nasal spray in the acute treatment of cluster headache: a double-blind study.
Topics: Acute Disease; Administration, Intranasal; Adult; Aged; Cluster Headache; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazolidinones; Placebo Effect; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2007 |
Patient preference for triptan formulations: a prospective study with zolmitriptan.
Topics: Adolescent; Adult; Aged; Chemistry, Pharmaceutical; Cross-Over Studies; Disability Evaluation; Female; Humans; Longitudinal Studies; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2007 |
Difference in triptan effect in patients with migraine and early allodynia.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Face; Female; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Oxazolidinones; Pain Measurement; Serotonin Receptor Agonists; Skin; Somatosensory Disorders; Sumatriptan; Treatment Outcome; Trigeminal Nerve; Tryptamines | 2008 |
Oral zolmitriptan in the short-term prevention of menstrual migraine: a randomized, placebo-controlled study.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Menstruation Disturbances; Middle Aged; Migraine Disorders; Oxazolidinones; Retrospective Studies; Serotonin Receptor Agonists; Time Factors; Tryptamines | 2008 |
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2008 |
Zolmitriptan compared to propranolol in the treatment of acute neuroleptic-induced akathisia: a comparative double-blind study.
Topics: Adrenergic beta-Antagonists; Adult; Akathisia, Drug-Induced; Anticonvulsants; Blood Pressure; Double-Blind Method; Epilepsy; Female; Humans; Inpatients; Male; Middle Aged; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Severity of Illness Index; Time Factors; Tryptamines | 2009 |
Nitroglycerin provocation in normal subjects is not a useful human migraine model?
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Migraine Disorders; Models, Biological; Nitroglycerin; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; Vasodilator Agents; Young Adult | 2010 |
Zolmitriptan nasal spray in the acute treatment of cluster headache: a meta-analysis of two studies.
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Cluster Headache; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazolidinones; Placebo Effect; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Young Adult | 2009 |
Zolmitriptan and human aggression: interaction with alcohol.
Topics: Adult; Aggression; Breath Tests; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Female; Humans; Male; Oxazolidinones; Placebos; Serotonin Receptor Agonists; Tryptamines | 2010 |
Frovatriptan versus zolmitriptan for the acute treatment of migraine: a double-blind, randomized, multicenter, Italian study.
Topics: Adolescent; Adult; Aged; Carbazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Patient Selection; Serotonin Receptor Agonists; Surveys and Questionnaires; Treatment Outcome; Tryptamines | 2010 |
Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.
Topics: Adult; Analgesics; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Pain; Research Design; Serotonin 5-HT1 Receptor Antagonists; Tryptamines | 2011 |
Antimigraine efficacy of telcagepant based on patient's historical triptan response.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Pain; Surveys and Questionnaires; Tryptamines | 2011 |
Efficacy of frovatriptan in the acute treatment of menstrually related migraine: analysis of a double-blind, randomized, multicenter, Italian, comparative study versus zolmitriptan.
Topics: Adult; Analgesics; Carbazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Italy; Migraine Disorders; Oxazolidinones; Premenstrual Syndrome; Tryptamines | 2011 |
Frovatriptan versus zolmitriptan for the acute treatment of migraine with aura: a subgroup analysis of a double-blind, randomized, multicenter, Italian study.
Topics: Adult; Carbazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Italy; Male; Middle Aged; Migraine with Aura; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2012 |
Bioequivalence study of 2 orodispersible formulations of zolmitriptan 5 mg in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Databases, Factual; Double-Blind Method; Female; Half-Life; Humans; Male; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Tryptamines; Young Adult | 2012 |
Reduction of spinal sensory transmission by facilitation of 5-HT1B/D receptors in noninjured and spinal cord-injured humans.
Topics: Action Potentials; Adult; Double-Blind Method; Female; H-Reflex; Humans; Male; Middle Aged; Motor Neurons; Muscle Spasticity; Muscle, Skeletal; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Adrenergic, alpha-2; Serotonin 5-HT1 Receptor Agonists; Spinal Cord Injuries; Synaptic Transmission; Tryptamines | 2013 |
Zolmitriptan inhibits neurogenic inflammation and pain during electrical stimulation in human skin.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Migraine Disorders; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Oxazolidinones; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Serotonin Receptor Agonists; Skin; Tryptamines; Young Adult | 2015 |
Theory-based analysis of clinical efficacy of triptans using receptor occupancy.
Topics: Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2014 |
Efficacy and tolerability of zolmitriptan nasal spray for the treatment of acute migraine in adolescents: Results of a randomized, double-blind, multi-center, parallel-group study (TEENZ).
Topics: Adolescent; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Migraine with Aura; Migraine without Aura; Nasal Sprays; Oxazolidinones; Pain Measurement; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Tryptamines | 2016 |
Rapid systemic delivery of zolmitriptan using an adhesive dermally applied microarray.
Topics: Administration, Cutaneous; Adult; Cross-Over Studies; Drug Delivery Systems; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Management; Skin Physiological Phenomena; Tryptamines | 2017 |
Randomized, double-blind, placebo-controlled, parallel-group, multi-center study of the safety and efficacy of ADAM zolmitriptan for the acute treatment of migraine.
Topics: Administration, Cutaneous; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Transdermal Patch; Treatment Outcome; Tryptamines | 2018 |
Pullulan based oral thin film formulation of zolmitriptan: Development and optimization using factorial design.
Topics: Administration, Oral; Analysis of Variance; Drug Liberation; Drug Stability; Glucans; Humans; Hydrogen-Ion Concentration; Molecular Weight; Oxazolidinones; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tryptamines | 2018 |
Use of Most Bothersome Symptom as a Coprimary Endpoint in Migraine Clinical Trials: A Post-Hoc Analysis of the Pivotal ZOTRIP Randomized, Controlled Trial.
Topics: Adult; Biomarkers; Double-Blind Method; Humans; Hyperacusis; Injections, Intradermal; Migraine Disorders; Nausea; Outcome Assessment, Health Care; Oxazolidinones; Photophobia; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2018 |
Efficacy of ADAM Zolmitriptan for the Acute Treatment of Difficult-to-Treat Migraine Headaches.
Topics: Adult; Double-Blind Method; Female; Humans; Injections, Intradermal; Male; Middle Aged; Migraine Disorders; Nausea; Outcome Assessment, Health Care; Oxazolidinones; Pain Measurement; Serotonin 5-HT1 Receptor Agonists; Time Factors; Time-to-Treatment; Tryptamines | 2019 |
Development of a novel zolmitriptan intracutaneous microneedle system (Qtrypta™) for the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2020 |
221 other study(ies) available for oxazolidin-2-one and zolmitriptan
| Article | Year |
|---|---|
Extending therapeutic options? Prospects for the future.
Topics: Cerebrovascular Circulation; Forecasting; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
311C90 (Zolmitriptan), a novel centrally and peripheral acting oral 5-hydroxytryptamine-1D agonist: a comparison of its absorption during a migraine attack and in a migraine-free period.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1996 |
Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine?
Topics: Animals; Brain Stem; Cats; Cranial Sinuses; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; Injections, Intravenous; Migraine Disorders; Neural Inhibition; Neurons; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1996 |
311C90: patient profiles and typical case histories of migraine management.
Topics: Adult; Female; Humans; Male; Menstruation; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
Receptor specificity and trigemino-vascular inhibitory actions of a novel 5-HT1B/1D receptor partial agonist, 311C90 (zolmitriptan).
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Humans; Male; Muscle Contraction; Oxazoles; Oxazolidinones; Rabbits; Serotonin Receptor Agonists; Trigeminal Ganglion; Tryptamines | 1997 |
Direct evidence for central sites of action of zolmitriptan (311C90): an autoradiographic study in cat.
Topics: Animals; Autoradiography; Brain Stem; Cats; Central Nervous System; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Spinal Cord; Tryptamines | 1997 |
Is a central action of acute antimigraine drugs essential?
Topics: Analgesics; Animals; Brain; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Measuring central action of acute antimigraine drugs in humans.
Topics: Analgesics; Brain; Contingent Negative Variation; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Visual; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Would any acute treatment for migraine demonstrate recurrence?
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
Central sites of actions of zolmitriptan and sumatriptan: 5HT1B, 5HT1D and 5HT1F receptor distribution.
Topics: Central Nervous System; Humans; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
Attacking migraine headache from beginning to end.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The clinical pharmacokinetics of zolmitriptan.
Topics: Absorption; Adult; Case-Control Studies; Female; Humans; Liver Diseases; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 1997 |
Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat.
Topics: Afferent Pathways; Animals; Cats; Electric Stimulation; Homocysteine; Humans; Iontophoresis; Neurons; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Spinal Cord; Sumatriptan; Trigeminal Nerve; Tryptamines | 1997 |
Zolmitriptan receives migraine indication.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Oral migraine treatment approved.
Topics: Administration, Oral; Contraindications; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Rabies Vaccines; Serotonin Receptor Agonists; Tryptamines; United States; United States Food and Drug Administration | 1998 |
A triptan too far?
Topics: Acute Disease; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Pharmacological analysis of the haemodynamic effects of 5-HT1B/D receptor agonists in the normotensive rat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Drug Interactions; Heart Rate; Hemodynamics; Male; Oxazoles; Oxazolidinones; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 1998 |
Zolmitriptan for migraine.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Cortical spreading depression-associated hyperemia in rats: involvement of serotonin.
Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Hyperemia; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 1998 |
Comparison of more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat.
Topics: Animals; Cats; Cerebrovascular Circulation; Cranial Sinuses; Electric Stimulation; Gene Expression Regulation; Genes, fos; Migraine Disorders; Neurons, Afferent; Nociceptors; Oxazoles; Oxazolidinones; Pain; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission; Trigeminal Caudal Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal; Tryptamines; Vasoconstrictor Agents | 1998 |
It never hurts to check. Taking the time to read a label benefited this migraine sufferer.
Topics: Adult; Contraindications; Drug Labeling; Female; Humans; Medication Errors; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Education as Topic; Reading; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Effects of sumatriptan on coronary flow and left ventricular function in the isolated perfused guinea pig heart.
Topics: Animals; Coronary Circulation; Diastole; Dihydroergotamine; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxazoles; Oxazolidinones; Perfusion; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Ventricular Function, Left | 1998 |
Effects of the serotonin1B/1D receptor agonist zolmitriptan on motor cortical excitability in humans.
Topics: Adult; Brain; Electromyography; Female; Humans; Male; Motor Cortex; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
New "triptans" and other drugs for migraine.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents | 1998 |
Cranial vascular effects of zolmitriptan, a centrally active 5-HT1B/1D receptor partial agonist for the acute treatment of migraine.
Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Carotid Arteries; Cats; Cerebral Cortex; Disease Models, Animal; Dogs; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
The effects of 5-HT1A, 5-HT1B and 5-HT1D receptor agonists on trigeminal nociceptive neurotransmission in anaesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analgesics; Animals; Electric Stimulation; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1998 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
[Zolmitriptan].
Topics: Chemistry, Pharmaceutical; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Headache after frequent use of serotonin agonists zolmitriptan and naratriptan.
Topics: Adult; Female; Headache; Humans; Indoles; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Tryptamines | 1999 |
Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.
Topics: Animals; Binding, Competitive; Cell Line; Cold Temperature; COS Cells; HeLa Cells; Humans; Indoles; Kinetics; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Sumatriptan; Triazoles; Tritium; Tryptamines | 1999 |
Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cardiovascular System; Coronary Vessels; Dose-Response Relationship, Drug; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Ketanserin; Methiothepin; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tissue Distribution; Tryptamines; Vasoconstriction | 1999 |
Zolmitriptan.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Partial agonism at serotonin 5-HT1B and dopamine D2L receptors using a luciferase reporter gene assay.
Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Dihydroergotoxine; Dopamine Agonists; Genes, Reporter; Lisuride; Luciferases; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptors, Dopamine D2; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin; Serotonin Receptor Agonists; Tryptamines | 1999 |
Drug-induced headaches.
Topics: Analgesics, Non-Narcotic; Ergotamine; Headache; Humans; Indoles; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Efficacy of 5HT in migraine.
Topics: Action Potentials; Animals; Cats; Cranial Sinuses; Electric Stimulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 1999 |
Measuring event-related potentials.
Topics: Adult; Arousal; Contingent Negative Variation; Dexfenfluramine; Event-Related Potentials, P300; Evoked Potentials, Auditory, Brain Stem; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1999 |
Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptan.
Topics: Cimetidine; Clorgyline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Liver; Male; Microsomes, Liver; Omeprazole; Oxazoles; Oxazolidinones; Recombinant Proteins; Serotonin Receptor Agonists; Theophylline; Tryptamines | 1999 |
[Differentiated therapy of migraine attack].
Topics: Adult; Analgesics; Antiemetics; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Treatment Outcome; Tryptamines | 1999 |
Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Bufotenin; Chromatography, High Pressure Liquid; Humans; Indoles; Mass Spectrometry; Migraine Disorders; Molecular Structure; Oxazoles; Oxazolidinones; Piperidines; Sensitivity and Specificity; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Serotonin 5HT1B/1D receptor agonists abolish NMDA receptor-evoked enhancement of nitric oxide synthase activity and cGMP concentration in brain cortex slices.
Topics: Animals; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Nitric Oxide Synthase; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Auditory evoked potentials in the assessment of central nervous system effects of antimigraine drugs.
Topics: Adolescent; Adult; Cerebral Cortex; Evoked Potentials, Auditory; Female; Humans; Indoles; Male; Oxazoles; Oxazolidinones; Piperidines; Reproducibility of Results; Sample Size; Serotonin Receptor Agonists; Tryptamines | 1999 |
Spinal cord infarction during use of zolmitriptan: a case report.
Topics: Female; Humans; Infarction; Menstruation; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Spinal Cord; Tryptamines | 2000 |
Drug information incorrect.
Topics: Canada; Contraindications; Drug Interactions; France; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Tryptamines; Vasodilator Agents | 2000 |
Zolmitriptan stimulates a Ca(2+)-dependent K(+) current in C6 glioma cells stably expressing recombinant human 5-HT(1B) receptors.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Humans; Membrane Potentials; Oxadiazoles; Oxazoles; Oxazolidinones; Peptides; Piperazines; Potassium Channels; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Tetraethylammonium; Tryptamines; Tumor Cells, Cultured | 2000 |
Zolmitriptan reverses blink reflex changes induced during the migraine attack in humans.
Topics: Adolescent; Adult; Blinking; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Ganglion; Tryptamines; Vasoconstrictor Agents | 2000 |
Triptans to the rescue: effective therapy for migraine headaches in the workplace.
Topics: Absenteeism; Adult; Cost-Benefit Analysis; Efficiency; Female; Humans; Indoles; Injections, Subcutaneous; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Self Administration; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Workplace | 2000 |
A comment on time-to-event analysis for headache relief.
Topics: Analgesics; Headache; Humans; Indoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Triazoles; Tryptamines | 2000 |
Is oral zolmitriptan efficacious in the acute treatment of cluster headache?
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Cluster Headache; Cross-Over Studies; Double-Blind Method; Humans; Middle Aged; Multicenter Studies as Topic; Oxazolidinones; Pain Measurement; Randomized Controlled Trials as Topic; Reproducibility of Results; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2000 |
Treatment options for acute migraine.
Topics: Acute Disease; Adult; Female; Humans; Migraine Disorders; Oxazolidinones; Patient Selection; Practice Guidelines as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Oral zolmitriptan is effetive in the acute treatment of cluster headache.
Topics: Administration, Oral; Cluster Headache; Humans; Oxazolidinones; Tryptamines | 2000 |
Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?
Topics: Cohort Studies; Depression; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Referral and Consultation; Regression Analysis; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2000 |
What is the optimal strategy for managing acute migraine headaches?
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Disabled Persons; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Metoclopramide; Migraine Disorders; Oxazolidinones; Patient Selection; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2001 |
Zolmitriptan versus sumatriptan comparison trial.
Topics: Acute Disease; Clinical Trials as Topic; Communication; Humans; Migraine Disorders; Oxazolidinones; Publishing; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Decreased sensitivity of 5-HT(1D) receptors in melancholic depression.
Topics: Adult; Depressive Disorder; Female; Human Growth Hormone; Humans; Hydrocortisone; Male; Middle Aged; Oxazolidinones; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines | 2001 |
Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain.
Topics: Animals; Binding, Competitive; Brain; Cattle; Cerebral Cortex; Dose-Response Relationship, Drug; Extracellular Space; Indoles; Injections, Intravenous; Membranes; Microdialysis; Oxazolidinones; Pyridines; Pyrrolidines; Rats; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Tryptamines | 2001 |
An open preference study with sumatriptan 50 mg and zolmitriptan 2.5 mg in 100 migraine patients.
Topics: Adult; Chi-Square Distribution; Confidence Intervals; Cross-Over Studies; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis.
Topics: Administration, Oral; Adult; Double-Blind Method; Humans; Indoles; Migraine Disorders; Nausea; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2001 |
Zolmitriptan--a 5-HT1B/D agonist, alcohol, and aggression in mice.
Topics: Aggression; Alcohol Drinking; Animals; Central Nervous System Depressants; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanol; Female; Hippocampus; Male; Mice; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 2001 |
The cost effectiveness of stratified care in the management of migraine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Decision Support Techniques; Female; Health Care Costs; Humans; Male; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2001 |
[Zolmitriptan in treatment of migraine attack--the ARES Study].
Topics: Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Recurrence; Treatment Outcome; Tryptamines | 2000 |
Assessing patient preference in migraine treatment.
Topics: Clinical Trials as Topic; Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Research Design; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 2001 |
Simultaneous measurement of zolmitriptan and its major metabolites N-desmethylzolmitriptan and zolmitriptan N-oxide in human plasma by high-performance liquid chromatography with coulometric detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Oxazolidinones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tryptamines | 2002 |
[Migraine: a disease, not a symptom].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Atenolol; Diagnosis, Differential; Dihydroergotamine; Flunarizine; GABA Agents; Humans; Indoramin; Methysergide; Migraine Disorders; Oxazolidinones; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Valproic Acid; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Re: Zakrzewska JM. Cluster headache: review of the literature. Br J Oral Maxillofac Surg 2001; 39: 103-113.
Topics: Administration, Oral; Cluster Headache; Humans; Injections, Subcutaneous; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasodilator Agents | 2002 |
[Splenic infarction associated with Zolmitriptan use].
Topics: Female; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Splenic Infarction; Tryptamines | 2002 |
Comparison of triptan tablet consumption per attack: a prospective study of migraineurs in Spain.
Topics: Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prospective Studies; Serotonin Receptor Agonists; Sumatriptan; Tablets; Triazoles; Tryptamines | 2002 |
Triptans reduce the inflammatory response in bacterial meningitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Calcitonin Gene-Related Peptide; Cerebrovascular Circulation; Dura Mater; Humans; Indoles; Laser-Doppler Flowmetry; Leukocytes; Male; Meningitis, Pneumococcal; Mice; Mice, Inbred Strains; Oxadiazoles; Oxazolidinones; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Survival Rate; Tryptamines | 2002 |
Restoring migraine sufferers' ability to function normally: a comparison of rizatriptan and other triptans in randomized trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2002 |
The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.
Topics: Animals; Dihydroergotamine; Disease Models, Animal; Male; Migraine Disorders; Oxazolidinones; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Nerve Diseases; Tryptamines | 2002 |
Ergot and triptan overuse in Austria--an evaluation of clinical data and cost.
Topics: Adult; Aged; Austria; Ergot Alkaloids; Female; Headache; Humans; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders; Sumatriptan; Tryptamines | 2002 |
[Triptane. Zolmitriptan--fast and effective in migraine].
Topics: Drug Therapy, Combination; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2003 |
Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Genes, MDR; Humans; Indoles; Injections, Intravenous; Male; Mice; Mice, Mutant Strains; Miconazole; Microsomes, Liver; Oxazolidinones; Oxidoreductases, N-Demethylating; Phenotype; Piperidines; Pyrrolidines; Recombinant Proteins; Statistics as Topic; Sumatriptan; Triazoles; Troleandomycin; Tryptamines | 2003 |
Migraine prevalence and treatment patterns: the global Migraine and Zolmitriptan Evaluation survey.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics; Europe; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Prevalence; Serotonin Receptor Agonists; Surveys and Questionnaires; Tryptamines; United States | 2003 |
Transcranial Doppler in migraine attacks before and after treatment with oral zolmitriptan or sumatriptan.
Topics: Adult; Blood Flow Velocity; Cerebrovascular Circulation; Female; Humans; Male; Migraine without Aura; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; Ultrasonography, Doppler, Transcranial | 2003 |
Abnormal habituation of 'nociceptive' blink reflex in migraine--evidence for increased excitability of trigeminal nociception.
Topics: Adult; Analysis of Variance; Aspirin; Blinking; Female; Follow-Up Studies; Habituation, Psychophysiologic; Humans; Lysine; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Trigeminal Nerve; Tryptamines | 2003 |
[Improved pharmacokinetics. Fast tryptan with sustained response].
Topics: Administration, Oral; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Female; Headache; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Placebos; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Tryptamines | 2003 |
[Highly selective beginning. Associated symptoms and side effects in retrospect].
Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
In vitro metabolism of zolmitriptan in rat cytochromes induced with beta-naphthoflavone and the interaction between six drugs and zolmitriptan.
Topics: Animals; beta-Naphthoflavone; Cimetidine; Cytochrome P-450 CYP1A2; Diazepam; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Fluvoxamine; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Moclobemide; Oxazolidinones; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Species Specificity; Tryptamines | 2003 |
[Zolmitriptan-induced hepatotoxicity].
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2003 |
Effects of acute or chronic administration of anti-migraine drugs sumatriptan and zolmitriptan on serotonin synthesis in the rat brain.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Infusions, Parenteral; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Migraine Disorders; Oxazolidinones; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Sumatriptan; Tissue Distribution; Tryptamines | 2004 |
Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.
Topics: Administration, Oral; Adolescent; Adult; Humans; Injections; Middle Aged; Migraine Disorders; Oxazolidinones; Pain; Pain Measurement; Prospective Studies; Serotonin Receptor Agonists; Skin; Sumatriptan; Time Factors; Triazoles; Tryptamines | 2004 |
Zolmitriptan (Zomig) nasal spray for migraine.
Topics: Administration, Intranasal; Contraindications; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2004 |
Cerebral vasoconstriction and stroke after use of serotonergic drugs.
Topics: Antidepressive Agents; Brain; Cerebrovascular Circulation; Dietary Supplements; Drug and Narcotic Control; Ephedrine; Humans; Hypertension; Myocardial Infarction; Oxazolidinones; Risk; Serotonin Agents; Stroke; Sumatriptan; Syndrome; Tryptamines; Vasoconstriction | 2002 |
[HPLC determination of zolmitriptan and its related substances].
Topics: Chromatography, High Pressure Liquid; Oxazolidinones; Tryptamines | 2004 |
Managing migraines. New treatments focus on relieving pain fast--or heading off these headaches before they begin.
Topics: Administration, Intranasal; Botulinum Toxins, Type A; Fructose; Heart Septal Defects, Atrial; Humans; Migraine Disorders; Neuromuscular Agents; Neuroprotective Agents; Oxazolidinones; Serotonin Receptor Agonists; Sleep Bruxism; Topiramate; Tryptamines | 2004 |
Effects of chronic sumatriptan and zolmitriptan treatment on 5-HT receptor expression and function in rats.
Topics: Animals; Autoradiography; Basilar Artery; Coronary Vessels; Dura Mater; Male; Organ Culture Techniques; Oxazolidinones; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Trigeminal Ganglion; Tryptamines; Vasoconstriction | 2004 |
Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.
Topics: Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tryptamines | 2004 |
Fixed drug eruption of the penis due to zolmitriptan.
Topics: Adult; Drug Eruptions; Humans; Male; Migraine Disorders; Oxazolidinones; Penis; Serotonin Receptor Agonists; Tryptamines | 2004 |
[Unstable angina in relationship to intake of zolmitriptan].
Topics: Adult; Angina, Unstable; Electrocardiography; Female; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2004 |
High-performance liquid chromatographic analysis of zolmitriptan in human plasma using fluorescence detection.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Humans; Male; Oxazolidinones; Spectrometry, Fluorescence; Technology, Pharmaceutical; Tryptamines | 2004 |
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery.
Topics: Animals; Benzamides; Brain; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Female; Forecasting; Guinea Pigs; Iliac Artery; Indoles; Ketanserin; Male; Muscle Contraction; Muscle, Smooth; Oxadiazoles; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Impact of migraine on patients and their families: the Migraine And Zolmitriptan Evaluation (MAZE) survey--Phase III.
Topics: Absenteeism; Adult; Chronic Disease; Cost of Illness; Efficiency; Family Relations; Female; Health Care Surveys; Humans; Menstrual Cycle; Migraine Disorders; Oxazolidinones; Prevalence; Risk Factors; Serotonin Receptor Agonists; Sickness Impact Profile; Surveys and Questionnaires; Tryptamines | 2004 |
The therapeutic profile of zolmitriptan in clinical practice.
Topics: Adult; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Determination of zolmitriptan enantiomers in rat liver microsomes by chiral high performance liquid chromatography with fl uorescence detection.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorescence; Male; Microsomes, Liver; Oxazolidinones; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tryptamines | 2005 |
Acute myocardial infarction following the use of antimigraine therapy.
Topics: Female; Humans; Middle Aged; Myocardial Infarction; Oxazolidinones; Plasminogen Activators; Serotonin Receptor Agonists; Thrombolytic Therapy; Tissue Plasminogen Activator; Tryptamines | 2004 |
Quantification of zolmitriptan in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.
Topics: Humans; Oxazolidinones; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Serotonin Receptor Agonists; Tryptamines | 2004 |
Correlation between lipophilicity and triptan outcomes.
Topics: Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Statistics as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
A validated chiral LC method for the determination of zolmitriptan and its potential impurities.
Topics: Chromatography, Liquid; Drug Contamination; Oxazolidinones; Tryptamines | 2005 |
Role of alcohol consumption in escalation to violence.
Topics: Aggression; Alcohol Drinking; Analgesics, Non-Narcotic; Ethanol; Female; Humans; Male; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, GABA; Receptors, Serotonin; Tryptamines; Violence | 2004 |
Triptans induce vasoconstriction of human arteries and veins from the thoracic wall.
Topics: Aged; Aged, 80 and over; Arteries; Dose-Response Relationship, Drug; Female; Humans; Indoles; Male; Middle Aged; Oxazolidinones; Piperidines; Polymerase Chain Reaction; Serotonin Receptor Agonists; Sumatriptan; Thorax; Triazoles; Tryptamines; Vasoconstriction; Veins | 2005 |
A stability indicating LC method for zolmitriptan.
Topics: Acetonitriles; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Industry; Hydrogen-Ion Concentration; Hydrolysis; Models, Chemical; Oxazolidinones; Oxygen; Pharmaceutical Solutions; Photolysis; Reproducibility of Results; Sensitivity and Specificity; Serotonin Receptor Agonists; Solubility; Tryptamines | 2005 |
A validated chiral LC method for the enantiomeric separation of Zolmitriptan key intermediate, ZTR-5.
Topics: Amylose; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Industry; Isomerism; Models, Chemical; Molecular Structure; Oxazolidinones; Phenylcarbamates; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Time Factors; Tryptamines | 2005 |
Part II: clinical efficacy and tolerability of zolmitriptan orally disintegrating tablet in the acute treatment of migraine.
Topics: Acute Disease; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Therapeutic Equivalency; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Part IV: effects of zolmitriptan orally disintegrating tablet on migraine symptoms and ability to perform normal activities: a post-marketing surveillance study in Germany.
Topics: Activities of Daily Living; Administration, Oral; Adult; Female; Germany; Humans; Male; Migraine Disorders; Oxazolidinones; Product Surveillance, Postmarketing; Quality of Life; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
[Extrahepatic cholestasia during therapy with Zolmitriptan (AscoTop)].
Topics: Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Radionuclide Imaging; Serotonin Receptor Agonists; Tryptamines | 2005 |
Over-the-counter triptans--making the switch.
Topics: Drug and Narcotic Control; Drug Approval; Drug Interactions; Humans; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Pharmacies; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; United Kingdom | 2005 |
Intranasal mucoadhesive microemulsions of zolmitriptan: preliminary studies on brain-targeting.
Topics: Administration, Intranasal; Animals; Area Under Curve; Brain; Drug Compounding; Drug Delivery Systems; Emulsions; Mucous Membrane; Oxazolidinones; Rats; Serotonin Receptor Agonists; Technetium; Tissue Adhesives; Tissue Distribution; Tryptamines | 2005 |
Blood-brain barrier penetration of zolmitriptan--modelling of positron emission tomography data.
Topics: Blood-Brain Barrier; Carbon Radioisotopes; Female; Humans; Male; Models, Biological; Oxazolidinones; Positron-Emission Tomography; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 2006 |
The study of enantioseparation of zolmitriptan on vancomycin-bonded chiral stationary phase.
Topics: Anti-Bacterial Agents; Chemistry; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Ions; Kinetics; Models, Chemical; Oxazolidinones; Pharmaceutical Preparations; Serotonin Receptor Agonists; Stereoisomerism; Tryptamines; Vancomycin | 2005 |
Determination of zolmitriptan in human plasma by liquid chromatography-tandem mass spectrometry method: application to a pharmacokinetic study.
Topics: Administration, Oral; Chromatography, Liquid; Humans; Mass Spectrometry; Oxazolidinones; Reference Standards; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Serotonin Receptor Agonists; Tryptamines | 2006 |
[Medical treatment of migraine attacks in the child].
Topics: Acetaminophen; Age Factors; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Ergot Alkaloids; Humans; Ibuprofen; Life Style; Migraine Disorders; Oxazolidinones; Parents; Patient Education as Topic; Pediatrics; Piperidines; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Taste Disorders; Triazoles; Tryptamines; Vasoconstrictor Agents | 2006 |
Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons.
Topics: Animals; Barium; Calcium; Calcium Channels; Calcium Signaling; Dose-Response Relationship, Drug; Electrophysiology; GTP-Binding Proteins; Membrane Potentials; Neurotransmitter Agents; Oxazolidinones; Rats; Rats, Wistar; Sensory Receptor Cells; Trigeminal Nerve; Tryptamines | 2006 |
Renal infarction during the use of rizatriptan and zolmitriptan: two case reports.
Topics: Adult; Cluster Headache; Humans; Infarction; Kidney; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tomography, X-Ray Computed; Triazoles; Tryptamines | 2006 |
Daily morning hemifacial spasm in a patient with cluster headache.
Topics: Adult; Cluster Headache; Hemifacial Spasm; Humans; Male; Oxazolidinones; Secondary Prevention; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2006 |
Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.
Topics: Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Migraine Disorders; Oxazolidinones; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Serotonin Receptor Agonists; Tryptamines | 2007 |
Zolmitriptan uptake by human intestinal epithelial Caco-2 cells.
Topics: Absorption; Caco-2 Cells; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydrogen-Ion Concentration; Oxazolidinones; Serotonin Receptor Agonists; Temperature; Tryptamines | 2006 |
Improved migraine management in primary care: results of a patient treatment experience study using zolmitriptan orally disintegrating tablet.
Topics: Administration, Oral; Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Tablets; Treatment Outcome; Tryptamines | 2006 |
Hemifacial spasm and cluster headache.
Topics: Adult; Cluster Headache; Hemifacial Spasm; Humans; Male; Oxazolidinones; Secondary Prevention; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2007 |
[Intranasal zolmitriptan acts quickly].
Topics: Administration, Intranasal; Cluster Headache; Cross-Over Studies; Humans; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 2007 |
Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.
Topics: Analgesics, Non-Narcotic; Drug Combinations; Drug Costs; Humans; Ibuprofen; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Tryptamines | 2007 |
Characterization of the human basilar artery contractile response to 5-HT and triptans.
Topics: Basilar Artery; Female; Humans; In Vitro Techniques; Male; Middle Aged; Oxazolidinones; Piperidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2.
Topics: Aspirin; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cetirizine; Cimetidine; Diffusion; Dose-Response Relationship, Drug; Drug Interactions; Flunarizine; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Oxazolidinones; Permeability; Propranolol; Serotonin Receptor Agonists; Sodium-Hydrogen Exchangers; Tryptamines | 2007 |
The 1:1 inclusion compounds zolmitriptan-benzene and zolmitriptan-phenol.
Topics: Benzene; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Oxazolidinones; Phenol; Tryptamines | 2007 |
Renal ischaemic injuries during the use of zolmitriptan for treatment of migraines in a transplanted patient under tacrolimus therapy.
Topics: Adult; Female; Humans; Ischemia; Kidney Transplantation; Migraine Disorders; Oxazolidinones; Postoperative Complications; Serotonin Antagonists; Treatment Outcome; Tryptamines | 2007 |
The impact of migraine: a case study.
Topics: Acupuncture Therapy; Administration, Rectal; Adult; Caffeine; Combined Modality Therapy; Drug Combinations; Ergotamine; Fructose; Humans; Male; Manipulation, Chiropractic; Middle Aged; Migraine Disorders; Neuroprotective Agents; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Topiramate; Tryptamines; Vasoconstrictor Agents | 2007 |
Fabrication of molecularly imprinted hybrid monoliths via a room temperature ionic liquid-mediated nonhydrolytic sol-gel route for chiral separation of zolmitriptan by capillary electrochromatography.
Topics: Capillary Electrochromatography; Carboxylic Acids; Ionic Liquids; Methacrylates; Oxazolidinones; Phase Transition; Porosity; Serotonin Receptor Agonists; Silanes; Silicon Dioxide; Temperature; Tryptamines | 2008 |
Tactile-induced ultrasonic vocalization in the rat: a novel assay to assess anti-migraine therapies in vivo.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Investigational; Inflammation Mediators; Injections, Intraventricular; Injections, Subcutaneous; Ketorolac; Lipopolysaccharides; Male; Meningitis; Migraine Disorders; Morphine; Nociceptors; Oxazolidinones; Pain Threshold; Rats; Rats, Sprague-Dawley; Touch; Trigeminal Nerve; Tryptamines; Vocalization, Animal | 2008 |
Controlled non-invasive transdermal iontophoretic delivery of zolmitriptan hydrochloride in vitro and in vivo.
Topics: Administration, Cutaneous; Animals; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Iontophoresis; Oxazolidinones; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Swine; Tryptamines | 2009 |
A study of the interaction between enantiomers of zolmitriptan and hydroxypropyl-beta-cyclodextrin by capillary electrophoresis.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Electrochemistry; Electrolytes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Molecular Conformation; Oxazolidinones; Phosphoric Acids; Stereoisomerism; Temperature; Thermodynamics; Tryptamines | 2009 |
Male-specific induction of CYP3A2 in rats by zolmitriptan.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Diazepam; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Immunoblotting; Male; Membrane Proteins; Midazolam; Oxazolidinones; Polymerase Chain Reaction; Rats; RNA, Messenger; Serotonin Receptor Agonists; Sex Factors; Testosterone; Tryptamines | 2008 |
CGRP-receptor antagonism in migraine treatment.
Topics: Animals; Azepines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cerebrovascular Circulation; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2008 |
Alcohol and cluster headaches.
Topics: Alcohol Drinking; Cluster Headache; Humans; Male; Middle Aged; Oxazolidinones; Serotonin Receptor Agonists; Smoking; Triazoles; Tryptamines | 2009 |
Migraine and telcagepant [corrected].
Topics: Dipeptides; Humans; Migraine Disorders; Oxazolidinones; Piperazines; Quality of Life; Quinazolines; Treatment Outcome; Tryptamines | 2009 |
Molecule of the month. Telcagepant.
Topics: Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Tryptamines | 2009 |
[Cluster headache].
Topics: Administration, Intranasal; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Cluster Headache; Ergotamine; Female; Humans; Injections, Subcutaneous; Male; Oxazolidinones; Seasons; Serotonin Receptor Agonists; Sex Factors; Sumatriptan; Time Factors; Tryptamines; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2009 |
[Induction of rat hepatic cytochrome P-450 3A by zolmitriptan mediated with pregnane X receptor].
Topics: Animals; Cytochrome P-450 CYP3A; Liver; Oxazolidinones; Pregnane X Receptor; Rats; Receptors, Steroid; Tryptamines | 2009 |
Preparation of zolmitriptan-chitosan microparticles by spray drying for nasal delivery.
Topics: Administration, Intranasal; Capsules; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Oxazolidinones; Particle Size; Powders; Tryptamines; X-Ray Diffraction | 2009 |
Rizatriptan. Comparative trial results.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents; Young Adult | 2000 |
Drug dependence associated with triptans and ergot derivatives: a case/non-case study.
Topics: Claviceps; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Risk; Substance-Related Disorders; Sumatriptan; Tryptamines | 2010 |
Micellar nanocarriers: potential nose-to-brain delivery of zolmitriptan as novel migraine therapy.
Topics: Animals; Brain; Female; Humans; Male; Micelles; Migraine Disorders; Nanostructures; Oxazolidinones; Rats; Rats, Wistar; Serotonin Receptor Agonists; Tryptamines | 2010 |
Prinzmetal-variant angina in a patient using zolmitriptan and citalopram.
Topics: Angina Pectoris, Variant; Citalopram; Coronary Angiography; Coronary Vasospasm; Drug Therapy, Combination; Electrocardiography; Female; Humans; Middle Aged; Myocardial Infarction; Oxazolidinones; Serotonin Agents; Tryptamines | 2010 |
Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Coronary Vessels; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Middle Aged; Migraine Disorders; Oxazolidinones; Tryptamines; Vasoconstriction; Vasodilation; Vasodilator Agents | 2010 |
Anodic voltammetry of zolmitriptan at boron-doped diamond electrode and its analytical applications.
Topics: Algorithms; Boron; Calibration; Diamond; Electrochemistry; Electrodes; Humans; Indicators and Reagents; Oxazolidinones; Reference Standards; Reproducibility of Results; Serotonin Receptor Agonists; Tablets; Tryptamines | 2010 |
Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries.
Topics: Adult; Aged; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Coronary Vessels; Cyclic AMP; Female; Humans; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth, Vascular; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; Young Adult | 2010 |
N-methyl-D-aspartate receptor-mediated modulations of the anti-allodynic effects of 5-HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Cycloserine; Dihydroergotamine; Disease Models, Animal; Drug Synergism; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Motor Activity; Oxazolidinones; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatica; Serotonin 5-HT1 Receptor Agonists; Trigeminal Neuralgia; Tryptamines | 2011 |
Formulation of zolmitriptan sublingual tablets prepared by direct compression with different polymers: in vitro and in vivo evaluation.
Topics: Administration, Sublingual; Animals; Chemical Phenomena; Compressive Strength; Drug Compounding; Drug Delivery Systems; Excipients; Female; Lactose; Oxazolidinones; Permeability; Polymers; Serotonin 5-HT1 Receptor Agonists; Sheep; Solubility; Tablets; Tryptamines | 2011 |
Evolution of paediatric off-label use after new significant medicines become available for adults: a study on triptans in Finnish children 1994-2007.
Topics: Adolescent; Adult; Age Factors; Child; Drug Approval; Female; Finland; Humans; Male; Migraine Disorders; Off-Label Use; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Time Factors; Triazoles; Tryptamines; Young Adult | 2011 |
Preparation and evaluation of zolmitriptan submicron emulsion for rapid and effective nasal absorption in beagle dogs.
Topics: Absorption; Administration, Intranasal; Amines; Animals; Area Under Curve; Biological Availability; Cilia; Dogs; Drug Delivery Systems; Emulsions; Models, Animal; Nasal Mucosa; Oxazolidinones; Particle Size; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2011 |
Evaluation of submicron emulsion as vehicles for rapid-onset intranasal delivery and improvement in brain targeting of zolmitriptan.
Topics: Administration, Intranasal; Amines; Animals; Area Under Curve; Biological Availability; Brain; Cerebral Ventricles; Drug Delivery Systems; Emulsions; Glycerol; Injections, Intravenous; Lecithins; Oleic Acid; Oxazolidinones; Particle Size; Pharmaceutical Vehicles; Poloxamer; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Solubility; Static Electricity; Triglycerides; Tryptamines | 2011 |
Influence of formulation variables in transdermal drug delivery system containing zolmitriptan.
Topics: Adhesives; Administration, Cutaneous; Animals; Crystallization; Cyclohexanols; Cyclohexenes; Drug Delivery Systems; Eucalyptol; Excipients; Limonene; Mice; Mice, Hairless; Monoterpenes; Oxazolidinones; Permeability; Polyethylene Glycols; Povidone; Serotonin 5-HT1 Receptor Agonists; Skin Absorption; Solvents; Terpenes; Transdermal Patch; Tryptamines | 2011 |
Zolmitriptan induced acute coronary syndrome: a unique case.
Topics: Acute Coronary Syndrome; Chest Pain; Electrocardiography; Humans; Male; Middle Aged; Migraine Disorders; Myocardial Infarction; Nitroglycerin; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Vasodilator Agents | 2011 |
Surface thermodynamics of mucoadhesive dry powder formulation of zolmitriptan.
Topics: Adhesiveness; Animals; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Hypromellose Derivatives; Methylcellulose; Molecular Weight; Mucins; Nasal Mucosa; Oxazolidinones; Powders; Serotonin 5-HT1 Receptor Agonists; Surface Properties; Sus scrofa; Technology, Pharmaceutical; Thermodynamics; Tryptamines | 2011 |
Identification, preparation and UHPLC determination of process-related impurity in zolmitriptan.
Topics: Chemistry Techniques, Synthetic; Chromatography, High Pressure Liquid; Drug Contamination; Limit of Detection; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxazoles; Oxazolidinones; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tryptamines | 2012 |
Fast relief from migraine attacks using fast-disintegrating sublingual zolmitriptan tablets.
Topics: Administration, Sublingual; Animals; Biological Availability; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Rabbits; Serotonin 5-HT1 Receptor Agonists; Solubility; Tablets; Time Factors; Tryptamines | 2012 |
[Myocardial infarction after taking zolmitriptan].
Topics: Aged; Humans; Male; Myocardial Infarction; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2012 |
Zolmitriptan-induced acute myocardial infarction.
Topics: Administration, Oral; Anterior Wall Myocardial Infarction; Cardiac Catheterization; Coronary Angiography; Electrocardiography; Female; Humans; Middle Aged; Migraine with Aura; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2012 |
Clinical reasoning: a 62-year-old migraineur with a new kind of headache attacks.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Magnetic Resonance Angiography; Male; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2012 |
Determination of zolmitriptan and its primary metabolite, n-desmethy-zolmitriptan, in rat plasma by LC-MS-MS.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Liquid-Liquid Extraction; Male; Oxazolidinones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tryptamines | 2013 |
Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Male; Oxazolidinones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tryptamines | 2012 |
Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines.
Topics: Cluster Headache; Drug Evaluation; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2012 |
[CME "Takotsubo cardiomyopathy].
Topics: Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential; Female; Humans; Migraine Disorders; Myocardial Ischemia; Oxazolidinones; Patient Education as Topic; Risk Factors; Serotonin 5-HT1 Receptor Agonists; Stress, Psychological; Takotsubo Cardiomyopathy; Tryptamines | 2012 |
Rheological evaluation of thermoreversible and mucoadhesive nasal gels of Zolmitriptan.
Topics: Administration, Intranasal; Chemistry, Pharmaceutical; Gels; Hydrogen-Ion Concentration; Oxazolidinones; Poloxamer; Sterilization; Temperature; Tryptamines; Viscosity | 2012 |
Influence of polymeric microcarriers on the in vivo intranasal uptake of an anti-migraine drug for brain targeting.
Topics: Adhesives; Administration, Intranasal; Administration, Intravenous; Animals; Area Under Curve; Brain; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Glutamic Acid; Hypromellose Derivatives; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Permeability; Polymers; Powders; Swine; Tryptamines | 2013 |
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Body Weight; Carbon Tetrachloride; Catecholamines; Common Bile Duct; Cyclic AMP; Drug Synergism; Drug Therapy, Combination; Hypertension, Portal; Infusions, Intravenous; Ligation; Liver Cirrhosis, Experimental; Lypressin; Mesenteric Artery, Superior; Oxazolidinones; Perfusion; Portal Pressure; Propranolol; Rats; Regional Blood Flow; Renal Artery; Splanchnic Circulation; Sympathectomy; Terlipressin; Tryptamines; Vasodilation | 2013 |
A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers.
Topics: Adult; Benzopyrans; Brain; Carbon Radioisotopes; Humans; Male; Morpholines; Oxazolidinones; Piperazines; Positron-Emission Tomography; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Young Adult | 2013 |
Systematic identification of proteins that elicit drug side effects.
Topics: Algorithms; Animals; Clinical Trials as Topic; Female; Gene Expression; Gene Expression Profiling; Humans; Hyperesthesia; Male; Mice; Oxazolidinones; Pharmacogenetics; Phenols; Predictive Value of Tests; Receptors, Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Sulfonamides; Tryptamines | 2013 |
Frovatriptan vs. other triptans for the acute treatment of oral contraceptive-induced menstrual migraine: pooled analysis of three double-blind, randomized, crossover, multicenter studies.
Topics: Carbazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Double-Blind Method; Female; Humans; Menstruation; Migraine Disorders; Multicenter Studies as Topic; Oxazolidinones; Premenstrual Syndrome; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2013 |
A selective and sensitive UPLC-MS/MS approach for trace level quantification of four potential genotoxic impurities in zolmitriptan drug substance.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Oxazolidinones; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tryptamines | 2013 |
A rapid and sensitive HPLC assay of some concomitant anti-migraine drugs.
Topics: Analgesics; Chromatography, High Pressure Liquid; Linear Models; Naproxen; Oxazolidinones; Propranolol; Reproducibility of Results; Sensitivity and Specificity; Tryptamines | 2014 |
Zolmitriptan oxalate and zolmitriptan camphorsulfonate: the first structural study of salt complexes of the antimigraine drug zolmitriptan.
Topics: Crystallography, X-Ray; Migraine Disorders; Molecular Structure; Oxalates; Oxazolidinones; Salts; Tryptamines | 2013 |
Formulation and evaluation of chitosan-chondroitin sulphate based nasal inserts for zolmitriptan.
Topics: Administration, Intranasal; Brain; Chemistry, Pharmaceutical; Chitosan; Chondroitin Sulfates; Drug Delivery Systems; Humans; Microscopy, Electron, Scanning; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2013 |
Formulation and in vitro evaluation of xanthan gum-based bilayered mucoadhesive buccal patches of zolmitriptan.
Topics: Adhesiveness; Chemistry, Pharmaceutical; Delayed-Action Preparations; Hydrogen-Ion Concentration; Mouth Mucosa; Oxazolidinones; Polysaccharides, Bacterial; Surface Properties; Tensile Strength; Time Factors; Tryptamines | 2014 |
Duel-acting subcutaneous microemulsion formulation for improved migraine treatment with zolmitriptan and diclofenac: formulation and in vitro-in vivo characterization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Migraine Disorders; Oxazolidinones; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2014 |
Images of an occlusive arterial disease of lower extremity due to chronic intoxication by ergot alkaloid.
Topics: Arterial Occlusive Diseases; Clopidogrel; Drug Substitution; Female; Humans; Lower Extremity; Methysergide; Middle Aged; Migraine Disorders; Oxazolidinones; Platelet Aggregation Inhibitors; Predictive Value of Tests; Serotonin 5-HT1 Receptor Agonists; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Tryptamines; Vasoconstrictor Agents | 2014 |
Optimization of combinational intranasal drug delivery system for the management of migraine by using statistical design.
Topics: Adhesives; Administration, Intranasal; Animals; Disease Management; Drug Delivery Systems; Gels; Ketorolac; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Sheep; Tryptamines | 2015 |
Drug in Adhesive Patch of Zolmitriptan: Formulation and In vitro /In vivo Correlation.
Topics: Adhesives; Administration, Cutaneous; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Male; Oxazolidinones; Permeability; Rabbits; Skin; Skin Absorption; Transdermal Patch; Tryptamines | 2015 |
Bioenhanced sublingual tablet of drug with limited permeability using novel surfactant binder and microencapsulated polysorbate: In vitro/in vivo evaluation.
Topics: Administration, Sublingual; Animals; Area Under Curve; Chickens; Drug Compounding; Excipients; Healthy Volunteers; Humans; Oral Mucosal Absorption; Oxazolidinones; Permeability; Poloxalene; Polysorbates; Silicon Dioxide; Solubility; Surface-Active Agents; Tablets; Tissue Distribution; Tryptamines | 2015 |
Comparative evolution of carotidynia on ultrasound and magnetic resonance imaging.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiphospholipid Syndrome; Arteritis; Carotid Artery Diseases; Carotid Artery, Common; Carotid Artery, Internal; Contraindications; Diagnosis, Differential; Humans; Lymphoma, B-Cell; Magnetic Resonance Imaging; Male; Middle Aged; Neck Pain; Oxazolidinones; Thyroiditis; Tryptamines; Ultrasonography, Doppler, Duplex | 2015 |
Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan and N-desmethyl zolmitriptan in human plasma: a sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study.
Topics: Chromatography, Liquid; Humans; Linear Models; Male; Oxazolidinones; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptamines | 2016 |
Triptans attenuate circadian responses to light.
Topics: Animals; Circadian Rhythm; Cricetinae; Excitatory Amino Acid Agonists; Genes, fos; Male; Mesocricetus; N-Methylaspartate; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Suprachiasmatic Nucleus; Tryptamines | 2015 |
Development of zolmitriptan loaded PLGA/poloxamer nanoparticles for migraine using quality by design approach.
Topics: Animals; Brain; Calorimetry, Differential Scanning; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Liberation; Lactic Acid; Male; Mice; Migraine Disorders; Nanoparticles; Oxazolidinones; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Serotonin 5-HT1 Receptor Agonists; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Tryptamines; X-Ray Diffraction | 2016 |
Poloxamer 407-based intranasal thermoreversible gel of zolmitriptan-loaded nanoethosomes: formulation, optimization, evaluation and permeation studies.
Topics: Acrylates; Administration, Intranasal; Chemistry, Pharmaceutical; Drug Liberation; Gels; Hypromellose Derivatives; Nanoparticles; Oxazolidinones; Poloxamer; Temperature; Tryptamines | 2016 |
Intranasal Pharmacokinetic Data for Triptans Such as Sumatriptan and Zolmitriptan Can Render Area Under the Curve (AUC) Predictions for the Oral Route: Strategy Development and Application.
Topics: Administration, Intranasal; Administration, Oral; Area Under Curve; Humans; Models, Biological; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Tryptamines | 2016 |
Trans-nasal zolmitriptan novasomes: in-vitro preparation, optimization and in-vivo evaluation of brain targeting efficiency.
Topics: Administration, Intranasal; Administration, Oral; Animals; Brain; Chemistry, Pharmaceutical; Drug Delivery Systems; Male; Mice; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Particle Size; Surface-Active Agents; Tryptamines | 2016 |
[Myocardial infarction in a patient free of coronary artery disease].
Topics: Humans; Myocardial Infarction; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2016 |
Firing characteristics of deep dorsal horn neurons after acute spinal transection during administration of agonists for 5-HT1B/1D and NMDA receptors.
Topics: Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Interneurons; Mice, Inbred BALB C; Mice, Inbred C57BL; Microelectrodes; N-Methylaspartate; Oxazolidinones; Posterior Horn Cells; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, N-Methyl-D-Aspartate; Sacrum; Serotonin 5-HT1 Receptor Agonists; Spinal Cord Injuries; Tissue Culture Techniques; Tryptamines | 2016 |
Intranasal Eutectic Powder of Zolmitriptan with Enhanced Bioavailability in the Rat Brain.
Topics: Administration, Intranasal; Animals; Brain; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Drug Delivery Systems; Nasal Mucosa; Oxazolidinones; Particle Size; Rats; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Tryptamines; X-Ray Diffraction | 2016 |
Bursting deep dorsal horn neurons: the pharmacological target for the antispastic effects of zolmitriptan?
Topics: Oxazolidinones; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tryptamines | 2017 |
Preclinical Evidence That 5-HT1B Receptor Agonists Show Promise as Medications for Psychostimulant Use Disorders.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methamphetamine; Motor Activity; Oxazolidinones; Pyridines; Random Allocation; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Reinforcement Schedule; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2017 |
One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan.
Topics: Administration, Intranasal; Administration, Oral; Animals; Area Under Curve; Biological Availability; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Male; Migraine Disorders; Oxazolidinones; Pyrrolidines; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tryptamines | 2017 |
Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
Topics: Administration, Intranasal; Adolescent; Adult; Body Weight; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Young Adult | 2017 |
Brain targeting efficiency of antimigrain drug loaded mucoadhesive intranasal nanoemulsion.
Topics: Administration, Intranasal; Animals; Brain; Chemistry, Pharmaceutical; Mice; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Tryptamines | 2017 |
Drug-induced Myopia and Bilateral Angle Closure Secondary to Zolmitriptan.
Topics: Adult; Female; Glaucoma, Angle-Closure; Humans; Migraine Disorders; Myopia; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2017 |
Development of zolmitriptan transfersomes by Box-Behnken design for nasal delivery: in vitro and in vivo evaluation.
Topics: Administration, Intranasal; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Lecithins; Male; Migraine Disorders; Oxazolidinones; Particle Size; Polysorbates; Rats; Rats, Wistar; Solubility; Surface-Active Agents; Tryptamines | 2018 |
A coupled bimodal SPECT-CT imaging and brain kinetics studies of zolmitriptan-encapsulated nanostructured polymeric carriers.
Topics: Administration, Intranasal; Administration, Intravenous; Animals; Brain; Chitosan; Drug Carriers; Kinetics; Male; Mice; Nanostructures; Oxazolidinones; Polyphosphates; Serotonin 5-HT1 Receptor Agonists; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tryptamines | 2018 |
Mechanistic insights of the controlled release properties of amide adhesive and hydroxyl adhesive.
Topics: Adhesives; Amides; Animals; Cyclooxygenase 2 Inhibitors; Delayed-Action Preparations; Drug Liberation; Etodolac; Hydroxyl Radical; Male; Models, Molecular; Oxazolidinones; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Skin; Skin Absorption; Transdermal Patch; Tryptamines | 2018 |
Pharmacokinetics and Skin Tolerability of Intracutaneous Zolmitriptan Delivery in Swine Using Adhesive Dermally Applied Microarray.
Topics: Administration, Cutaneous; Animals; Biological Availability; Drug Delivery Systems; Equipment Design; Female; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Skin; Skin Absorption; Swine; Transdermal Patch; Tryptamines | 2018 |
[Induction study of CYP3A2 in male rats by zolmitriptan].
Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Growth Hormone; Hepatocyte Nuclear Factor 4; Male; Oxazolidinones; Rats; RNA, Messenger; Sex Factors; Sodium Glutamate; Tryptamines | 2017 |
Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; HEK293 Cells; Humans; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Oxazolidinones; Pharmaceutical Preparations; Proteomics; Tryptamines | 2018 |
Administration of 5-HT-1B agonist ameliorates pseudodementia induced by depression in rats.
Topics: Animals; Depression; Factitious Disorders; Male; Oxazolidinones; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2018 |
Cost-Effectiveness of Reclassifying Triptans in Australia: Application of an Economic Evaluation Approach to Regulatory Decisions.
Topics: Australia; Cost-Benefit Analysis; Drug and Narcotic Control; General Practitioners; Humans; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Pharmacists; Prescription Drugs; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Tryptamines | 2019 |
Investigation of Effect of Isopropyl Palmitate on Drug Release from Transdermal Patch and Molecular Dynamics Study.
Topics: Adhesives; Administration, Cutaneous; Animals; Drug Delivery Systems; Drug Liberation; Male; Molecular Dynamics Simulation; Oxazolidinones; Palmitates; Rats; Skin Absorption; Transdermal Patch; Tryptamines | 2019 |
Zolmitriptan attenuates hepatocellular carcinoma via activation of caspase mediated apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cytokines; Disease Models, Animal; Glutathione; Lipids; Liver; Liver Neoplasms; Male; Nitric Oxide Synthase Type II; Oxazolidinones; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Tryptamines | 2019 |
Pharmacokinetic study and brain tissue analysis of Zolmitriptan loaded chitosan nanoparticles in rats by LC-MS method.
Topics: Administration, Intranasal; Animals; Brain; Chitosan; Chromatography, Liquid; Disease Models, Animal; Male; Migraine Disorders; Nanoparticles; Oxazolidinones; Particle Size; Rats; Rats, Wistar; Tandem Mass Spectrometry; Tryptamines | 2020 |
Could inhaled drug formulations be the future of acute migraine treatment?
Topics: Administration, Inhalation; Administration, Intranasal; Blood-Brain Barrier; Dihydroergotamine; Dopamine Agonists; Humans; Metered Dose Inhalers; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2019 |
Assessment Of Spanlastic Vesicles Of Zolmitriptan For Treating Migraine In Rats.
Topics: Administration, Intranasal; Animals; Injections, Intraperitoneal; Male; Migraine Disorders; Nitroglycerin; Oxazolidinones; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2019 |
Evaluation of OptiFlow™-MS/MS for bioanalysis of pharmaceutical drugs and metabolites.
Topics: Chromatography, High Pressure Liquid; Half-Life; Humans; Limit of Detection; Metoprolol; Oxazolidinones; Pharmaceutical Preparations; Tandem Mass Spectrometry; Tryptamines | 2020 |
Bursting interneurons in the deep dorsal horn develop increased excitability and sensitivity to serotonin after chronic spinal injury.
Topics: Action Potentials; Animals; Chronic Disease; Disease Models, Animal; Excitatory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred C57BL; Motor Neurons; N-Methylaspartate; Oxazolidinones; Posterior Horn Cells; Serotonin; Serotonin 5-HT1 Receptor Agonists; Spasm; Spinal Cord Injuries; Spinal Nerve Roots; Tryptamines | 2020 |
Quality by Design Approach for Preparation of Zolmitriptan/Chitosan Nanostructured Lipid Carrier Particles - Formulation and Pharmacodynamic Assessment.
Topics: Animals; Capsules; Chitosan; Drug Carriers; Emulsions; Gelatin; Lipids; Male; Mice; Nanoparticles; Nanostructures; Oxazolidinones; Particle Size; Pectins; Polysorbates; Solubility; Tryptamines; Ultrasonics | 2020 |
Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding.
Topics: Adult; Breast Feeding; Female; Humans; Infant; Infant, Newborn; Migraine Disorders; Milk, Human; Oxazolidinones; Piperidines; Pyrrolidines; Triazoles; Tryptamines | 2021 |
Effectiveness of medication in cluster headache.
Topics: Cluster Headache; Humans; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2021 |
Long term safety, tolerability, and efficacy of intracutaneous zolmitriptan (M207) in the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2021 |
Metabolic activation of zolmitriptan mediated by CYP2D6.
Topics: Activation, Metabolic; Animals; Cytochrome P-450 CYP2D6; Glutathione; Microsomes, Liver; Oxazolidinones; Rats; Tryptamines | 2021 |
Effect of Chemical Penetration Enhancer-Adhesive Interaction on Drug Release from Transdermal Patch: Mechanism Study Based on FT-IR Spectroscopy,
Topics: Adhesives; Administration, Cutaneous; Animals; Drug Liberation; Half-Life; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Male; Molecular Docking Simulation; Myristates; Oxazolidinones; Rats; Rats, Wistar; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Transdermal Patch; Tryptamines | 2021 |
Activation of 5-HT 1b/d receptor restores the cognitive function by reducing glutamate release, deposition of β-amyloid and TLR-4 pathway in the brain of scopolamine-induced dementia in rat.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Brain; Cognition; Cognitive Dysfunction; Dementia; Disease Models, Animal; Glutamic Acid; Glutathione; Glutathione Peroxidase; Maze Learning; Memory Disorders; Oxazolidinones; Oxidative Stress; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Scopolamine; Serotonin; Serotonin 5-HT1 Receptor Agonists; Superoxide Dismutase; Toll-Like Receptor 4; Tryptamines | 2021 |
The Potential Synergistic Activity of Zolmitriptan Combined in New Self-Nanoemulsifying Drug Delivery Systems: ATR-FTIR Real-Time Fast Dissolution Monitoring and Pharmacodynamic Assessment.
Topics: Administration, Oral; Animals; Biological Availability; Drug Delivery Systems; Drug Liberation; Emulsions; Nanoparticles; Oxazolidinones; Particle Size; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Tryptamines | 2021 |
Evaluation of Brain Targeting Potential of Zolmitriptan Mucoadhesive Nanoparticles for Intranasal Drug Delivery.
Topics: Administration, Intranasal; Animals; Brain; Male; Mice; Migraine Disorders; Nanoparticles; Oxazolidinones; Rats; Rats, Wistar; Tryptamines | 2022 |
Two spectroscopic methods for estimation of anti-migraine medications: Sumatriptan and Zolmitriptan based on nucleophilic substitution reaction.
Topics: Hydrogen-Ion Concentration; Oxazolidinones; Spectrometry, Fluorescence; Sumatriptan; Tablets; Tryptamines | 2022 |
Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats.
Topics: Amantadine; Animals; Antiparkinson Agents; Buspirone; Dyskinesia, Drug-Induced; Levodopa; Oxazolidinones; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2022 |
Development of a new rapid, economical and eco-friendly HPLC method for in vitro and in vivo determination of zolmitriptan.
Topics: Animals; Chromatography, High Pressure Liquid; Limit of Detection; Oxazolidinones; Rats; Reproducibility of Results | 2022 |