Page last updated: 2024-08-25

oxazolidin-2-one and metaxalone

oxazolidin-2-one has been researched along with metaxalone in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (14.29)	18.7374
1990's	1 (3.57)	18.2507
2000's	8 (28.57)	29.6817
2010's	12 (42.86)	24.3611
2020's	3 (10.71)	2.80

Authors

Authors	Studies
Dent, RW; Ervin, DK	1
Crain, GM; Gelber, DA; Jung, S; Markwell, SJ; Pfeifer, MA; Ross, DR; Schrage, JP; Schumer, MP	1
Daly, TM; Gruszecki, AC; Hardy, RW; Kloda, S; Robinson, CA; Simmons, GT	1
BROWN, WE	1
FATHIE, K	1
KLEBER, JW; LEE, CC; NASH, JF	1
Amann, A; Cacace, J; Reilly, EE	1
Kuykendall, JR; Rhodes, RS	1
Garside, D; Poklis, JL; Ropero-Miller, JD; Winecker, RE	1
Toth, PP; Urtis, J	1
Fowler, D; Levine, B; Moore, KA	1
Datla, PV; Kandikere, VN; Mudigonda, K; Nirogi, RV; Shrivastava, W; Shukla, M	1
Bo, L; Fan, X; Liu, X; Liu, Y; Zhang, J	1
Forrester, MB	2
Buxton, HT; Esposito, K; Furlong, ET; Kolpin, DW; Phillips, PJ; Smith, SG; Stinson, B; Zaugg, SD	1
Goswami, D; Gurule, S; Khuroo, A; Monif, T; Saha, A; Vats, P	1
Farah, H; Janarthan, M; Naidu, ChG; Rao, RN; Sahu, PK	1
Bosak, AR; Skolnik, AB	1
Cobb, T; Haswell, D; Hodgman, M; Martini, DI; Nacca, N	1
Curtis, B; Jenkins, C; Wiens, AL	1
Cook, MD; Nappe, TM; Surmaitis, RM	1
Bishop-Freeman, SC; Hensel, EM; Miller, A; Winecker, RE	1
Cetina-Čižmek, B; Filipović-Grčić, J; Khan, MZI; Radić, M; Špoljarić, D; Vuletić, L	1
Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E	1
Levy, RM; Yamaguchi, M	1
Altavilla, D; Bitto, A; Cardia, L; D'Ascola, A; Irrera, N; Mannino, F; Minutoli, L; Pallio, G; Picciolo, G; Squadrito, F; Squadrito, V	1
Chen, YZ; Cui, BD; Da, XY; Fu, HK; Han, WY; Wan, NW; Wang, HH; Wang, ZX	1

Reviews

1 review(s) available for oxazolidin-2-one and metaxalone

Article	Year
Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. Clinical therapeutics, 2004, Volume: 26, Issue:9 Topics: Amitriptyline; Carisoprodol; Humans; Low Back Pain; Muscle Relaxants, Central; Oxazolidinones; Randomized Controlled Trials as Topic; Risk Assessment	2004

Trials

3 trial(s) available for oxazolidin-2-one and metaxalone

Article	Year
A study of metaxalone (Skelaxin) vs. placebo in acute musculoskeletal disorders: a cooperative study. Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:3 Topics: Anthropometry; Clinical Trials as Topic; Drug Evaluation; Humans; Inflammation; Muscular Diseases; Oxazoles; Oxazolidinones; Pain; Placebos; Spasm; Wounds and Injuries	1975
A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy. Diabetes care, 1993, Volume: 16, Issue:8 Topics: Analgesics; Capsaicin; Diabetic Neuropathies; Exercise Therapy; Female; Glycated Hemoglobin; Humans; Imipramine; Male; Mexiletine; Middle Aged; Models, Neurological; Muscles; Oxazoles; Oxazolidinones; Pain; Pain Management; Pain Measurement; Piroxicam	1993
A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain. Annals of emergency medicine, 2019, Volume: 74, Issue:4 Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Baclofen; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Low Back Pain; Male; Muscle Relaxants, Central; Oxazolidinones; Treatment Outcome	2019

Other Studies

24 other study(ies) available for oxazolidin-2-one and metaxalone

Article	Year
Polydrug fatality involving metaxalone. Journal of forensic sciences, 2003, Volume: 48, Issue:2 Topics: Adult; Chlorpheniramine; Citalopram; Drug Overdose; Ethanol; Fatal Outcome; Female; Forensic Medicine; Histamine H1 Antagonists; Humans; Muscle Relaxants, Central; Oxazolidinones; Selective Serotonin Reuptake Inhibitors	2003
EVALUATION OF METAXALONE (SKELAXIN). JAMA, 1964, Jan-25, Volume: 187 Topics: Humans; Oxazolidinones	1964
A SECOND LOOK AT A SKELETAL MUSCLE RELAXANT: A DOUBLE-BLIND STUDY OF METAXALONE. Current therapeutic research, clinical and experimental, 1964, Volume: 6 Topics: Anticonvulsants; Back Pain; Biomedical Research; Double-Blind Method; Drug Therapy; Humans; Muscle Relaxants, Central; Nausea; Neuromuscular Agents; Oxazolidinones; Placebos; Polyuria; Spasm; Toxicology; Vertigo	1964
QUALITATIVE AND QUANTITATIVE TESTS FOR METAXALONE. Journal of pharmaceutical sciences, 1964, Volume: 53 Topics: Chemistry, Pharmaceutical; Oxazolidinones; Pharmacy	1964
Comparison of the dissolution of metaxalone tablets (Skelaxin) using USP Apparatus 2 and 3. AAPS PharmSciTech, 2004, Feb-06, Volume: 5, Issue:1 Topics: Delayed-Action Preparations; Hydrogen-Ion Concentration; Oxazolidinones; Solubility; Tablets; Technology, Pharmaceutical	2004
Auditory hallucinations elicited by combined meclizine and metaxalone use at bedtime. The Annals of pharmacotherapy, 2004, Volume: 38, Issue:11 Topics: Adult; Antiemetics; Drug Interactions; Hallucinations; Humans; Male; Meclizine; Oxazolidinones	2004
Metaxalone (Skelaxin)-related death. Journal of analytical toxicology, 2004, Volume: 28, Issue:6 Topics: Adult; Chromatography, Gas; Drug Overdose; Gas Chromatography-Mass Spectrometry; Humans; Male; Muscle Relaxants, Central; Oxazolidinones; Reference Standards; Suicide; Tissue Distribution	2004
A fatality involving metaxalone. Forensic science international, 2005, May-10, Volume: 149, Issue:2-3 Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver; Middle Aged; Muscle Relaxants, Central; Oxazolidinones; Suicide	2005
Quantification of metaxalone in human plasma by liquid chromatography coupled to tandem mass spectrometry. Journal of analytical toxicology, 2006, Volume: 30, Issue:4 Topics: Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Oxazolidinones; Reproducibility of Results; Sensitivity and Specificity	2006
Synthesis of poly(ethylene glycol)-metaxalone conjugates and study of its controlled release in vitro. International journal of pharmaceutics, 2007, Mar-06, Volume: 332, Issue:1-2 Topics: Acetates; Buffers; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chymotrypsin; Delayed-Action Preparations; Drug Carriers; Drug Stability; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Neuromuscular Agents; Oxazolidinones; Polyethylene Glycols; Prodrugs; Solubility; Spectroscopy, Fourier Transform Infrared	2007
Adult metaxalone ingestions reported to Texas poison control centers, 2000-2006. Human & experimental toxicology, 2010, Volume: 29, Issue:1 Topics: Adult; Adverse Drug Reaction Reporting Systems; Drug Overdose; Female; Guidelines as Topic; Humans; Male; Middle Aged; Neuromuscular Agents; Oxazolidinones; Poison Control Centers; Poisoning; Retrospective Studies; Texas; Triage; Young Adult	2010
Pediatric metaxalone ingestions reported to Texas poison control centers, 2000-2007. Pediatric emergency care, 2010, Volume: 26, Issue:1 Topics: Child, Preschool; Drug Overdose; Female; Humans; Incidence; Infant; Male; Neuromuscular Agents; Oxazolidinones; Poison Control Centers; Retrospective Studies; Texas	2010
Pharmaceutical formulation facilities as sources of opioids and other pharmaceuticals to wastewater treatment plant effluents. Environmental science & technology, 2010, Jul-01, Volume: 44, Issue:13 Topics: Analgesics, Opioid; Barbiturates; Carisoprodol; Drug Residues; Environmental Monitoring; Methadone; Muscle Relaxants, Central; Oxazolidinones; Oxycodone; Pharmaceutical Preparations; United States; Water Pollutants, Chemical; Water Purification	2010
Metaxalone estimation in biological matrix using high-throughput LC-MS/MS bioanalytical method. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Aug-01, Volume: 902 Topics: Adult; Chromatography, Liquid; Drug Stability; Hemolysis; High-Throughput Screening Assays; Humans; Hyperlipidemias; Linear Models; Male; Oxazolidinones; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry	2012
Development and validation of a stability-indicating assay including the isolation and characterization of degradation products of metaxalone by LC-MS. Biomedical chromatography : BMC, 2013, Volume: 27, Issue:12 Topics: Chromatography, Liquid; Drug Contamination; Hydrogen-Ion Concentration; Limit of Detection; Linear Models; Mass Spectrometry; Oxazolidinones; Reproducibility of Results	2013
Serotonin syndrome associated with metaxalone overdose. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2014, Volume: 10, Issue:4 Topics: Adult; Drug Overdose; Female; Humans; Middle Aged; Neuromuscular Agents; Oxazolidinones; Serotonin Syndrome	2014
Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor. Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:3 Topics: Adult; Citalopram; Drug Interactions; Drug Overdose; Female; Humans; Male; Neuromuscular Agents; Oxazolidinones; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Treatment Outcome	2015
A rare fatality attributed solely to metaxalone. Journal of analytical toxicology, 2015, Volume: 39, Issue:4 Topics: Accidents; Adult; Fatal Outcome; Female; Humans; Neuromuscular Agents; Oxazolidinones; Poisoning	2015
Serotonin syndrome associated with therapeutic metaxalone in a patient with cirrhosis. The American journal of emergency medicine, 2016, Volume: 34, Issue:2 Topics: Aged; Humans; Liver Cirrhosis; Male; Neuromuscular Agents; Oxazolidinones; Serotonin Syndrome	2016
Postmortem Metaxalone (Skelaxin®) Data from North Carolina. Journal of analytical toxicology, 2015, Volume: 39, Issue:8 Topics: Adult; Cause of Death; Female; Forensic Toxicology; Humans; Male; Oxazolidinones	2015
Development of a Clinically Relevant Dissolution Method for Metaxalone Immediate Release Formulations Based on an IVIVC Model. Pharmaceutical research, 2018, Jun-22, Volume: 35, Issue:8 Topics: Administration, Oral; Biological Availability; Caco-2 Cells; Delayed-Action Preparations; Drug Compounding; Humans; Male; Models, Biological; Neuromuscular Agents; Oxazolidinones; Solubility; Tablets; Therapeutic Equivalency	2018
Metaxalone Suppresses Production of Inflammatory Cytokines Associated with Painful Conditions in Mouse Macrophages RAW264.7 Cells Current molecular medicine, 2020, Volume: 20, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Drug Combinations; Drug Synergism; In Vitro Techniques; Inflammation; Inflammation Mediators; Macrophages; Mice; Neuromuscular Agents; Oxazolidinones; Polycyclic Sesquiterpenes; RAW 264.7 Cells	2020
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells. International journal of molecular sciences, 2021, Aug-05, Volume: 22, Issue:16 Topics: Anti-Inflammatory Agents; Cell Line; Humans; Inflammation; Interleukin-13; Interleukin-1beta; Interleukin-6; Microglia; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazolidinones; Phenotype; PPAR gamma; Signal Transduction; Tumor Necrosis Factor-alpha	2021
Biocatalytic Synthesis of Metaxalone and Its Analogues. Organic letters, 2023, 07-14, Volume: 25, Issue:27 Topics: Bacteria; Biocatalysis; Oxazolidinones; Protein Engineering	2023