Compounds > oxazolidin-2-one
Page last updated: 2024-08-25

oxazolidin-2-one and isoxazoles

oxazolidin-2-one has been researched along with isoxazoles in 153 studies

Research

Studies (153)

TimeframeStudies, this research(%)All Research%
pre-199017 (11.11)18.7374
1990's2 (1.31)18.2507
2000's27 (17.65)29.6817
2010's89 (58.17)24.3611
2020's18 (11.76)2.80

Authors

AuthorsStudies
Sato, M; Stammer, CH1
Gorecki, DK; Peesker, SJ; Wood, JD1
Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Nielsen, L1
Janda, J1
Antonious, GF; Byers, ME; Hilborn, D; Jarret, L; Tyess, D1
Ebert, B; Kemp, JA; Krogsgaard-Larsen, P; Wafford, KA; Whiting, PJ1
Antonious, GF3
Lichtenthaler, HK; Mueller, C; Schwender, J; Zeidler, J2
Gonçalves, FF; Martins, AF; Primel, EG; Zanella, R1
Burdett, AS; Macmillan, DL; Stevens, MM1
Luppi, G; Tomasini, C; Villa, M1
SHOJI, JI1
FORTUNI, M; MERENDA, P; MORETTI, E; SEDIARI, F1
MONACO, P1
CASCIO, G; MONACO, P1
LA GRUTTA, G; MONACO, P1
BENIGNO, P; MONACO, P1
TANAKA, N; UMEZAWA, H1
LUCIANI, L1
SALGARELLO, G2
Burrows, PM; Camper, ND; McDonald, SK1
Asami, T; Bajguz, A1
Dobozi, M; Horváth, S; Lehoczky, E1
Bush, K; Foleno, BD; Goldschmidt, R; Hilliard, JJ; Macielag, MJ; Melton, J; Weidner-Wells, MA; Werblood, HM; Wira, E1
Barrett, JF; Bronson, JJ; D'Andrea, SV; DenBleyker, KL; Frosco, M; Fung-Tomc, JC; Gill, P; Marinier, A; Martel, A; Mate, R; Meng, Z; Quesnelle, CA; Snyder, LB1
Guo, ZY; Li, GX; Li, LF; Liao, XY; Yang, RB1
TenBrook, PL; Tjeerdema, RS1
Angel Tierno, M; Baldisserotto, B; Crestani, M; dos Santos Miron, D; Maria Morsch, V; Moraes, G; Rosa Shettinger, M; Vieira, VL1
Crestani, M; Dos Santos Miron, D; Duarte, MF; Glusczak, L; Lazzari, R; Menezes, C; Morsch, VM; Pippi, AL; Vieira, VP1
Carreira, EM; Hauser, H; Kvaernø, L; Ritter, T; Werder, M1
Oliver, DP; Quayle, WC; Zrna, S1
Crestani, M; dos Santos Miron, D; Glusczak, L; Gonçalves, FF; Loro, VL; Menezes, C; Silveira, A; Spanevello, R; Zanella, R1
Bout, D; Clastre, M; Goubard, A; Laurent, F; Mincheva, Z; Prel, A; Rideau, M; Velge-Roussel, F; Viaud-Massuart, MC1
Liu, W; Sheng, GD; Xu, C1
Fischer, AJ; TenBrook, PL; Tjeerdema, RS; Yasuor, H1
Buckheit, RW; Cushman, M; De Clercq, E; Deng, BL; Hartman, TL; Pannecouque, C; Watson, K; Zhao, Y1
Crestani, M; Glusczak, L; Loro, VL; Miron, Ddos S; Morsch, VM; Pretto, A; Schetinger, MR1
Sachdev, N; Weimer, LH1
Corrêa, AX; Corrêa, R; Horita, CO; Radetski, CM; Radetski, MR; Tamanaha, MS1
Claassen, VP; Curtis, MJ; dela Cruz, ID; Gunasekara, AS; Tjeerdema, RS1
Kirtaeva, OV; Lazareva, IaR; Romanova, EV; Sokolova, GB; Tsybane, AA1
Holstege, DM; Tjeerdema, RS; Tomco, PL; Zou, W1
Fischer, AJ; Tjeerdema, RS; Tolstikov, VV; Yasuor, H; Zou, W1
Cantou, G; Carlomagno, M; González, D; González-Sapienza, G; Hammock, BD; Last, JA; Mathó, C; Roel, A; Sanborn, JR1
Caldas, SS; Costa, FP; Primel, EG1
Asami, T; Kuzuyama, T; Matsue, Y; Mizuno, H; Nishiyama, M; Tomita, T1
Newman, M1
Carlomagno, M; González-Sapienza, G; González-Techera, A; Hammock, BD; Last, J; Rossotti, MA1
Vora, A1
Diaz Kirmser, EM; Gonzalez, MC; Mártire, DO; Rosso, JA1
Cao, D; Deng, Z; Hu, J1
Cattaneo, R; Clasen, B; de Avila, LA; Loro, VL; Marchesan, E; Menezes, C; Moraes, BS; Pretto, A; Sartori, GM; Zanella, R1
Baudot, R; Cren-Olivé, C; Feidt, C; Fratta, C; Lazartigues, A; Thomas, M; Wiest, L1
Bugaenko, SE; Elistratova, NA; Maliev, BM; Mozhokina, GN; Sokolova, GB; Solov'eva, IP1
Andries, K; Bantubani, N; De Marez, T; Diacon, AH; Donald, PR; Grobusch, M; Lounis, N; Mahanyele, R; McNeeley, DF; Meyvisch, P; Narasimooloo, R; Patientia, RF; Pym, A; van Heeswijk, R1
Tjeerdema, RS; Tomco, PL1
Biswal, S1
Gonzalez-Sapienza, G; Gonzalez-Techera, A; Hammock, BD; Vanrell, L1
Berthelot, P; Boukhalfa, K; Caignard, DH; Delagrange, P; Ettaoussi, M; Landagaray, E; Rami, M; Yous, S1
Holmes, WE; Tjeerdema, RS; Tomco, PL1
Fernandes, MN; Martinez, CB; Pereira, L1
Davis, JG; Farley, J; Lancaster, J; Odendaal, R; Shean, K; Van der Walt, M1
An, Z; Bogs, J; Han, M; Heppel, SC; Rausch, T; Su, T; Zu, Y1
Bianchini, A; de Martinez Gaspar Martins, C; Gilberto Primel, E; Jaime de Menezes, E; Laura Venquiaruti Escarrone, A; Marian Bolzan, C; Souza Caldas, S1
Hwang, TJ; Jafarov, A; Jakubowiak, W; Keshavjee, S; Nunn, P; Wares, DF1
Abramović, BF; Četojević-Simin, DD; Csanádi, JJ; Despotović, VN; Orčić, DZ; Šojić, DV1
Feng, Y; Liu, J; Wei, J; Zhu, L1
Fan, X; Han, ZF; Hu, GS; Jia, JM; Li, N1
Barbosa, NBV; Leitemperger, J; Lópes, T; Loro, VL; Menezes, C; Neto, JR; Santi, A; Toni, C1
Brum, A; Dotta, G; Garcia, LP; Garcia, P; Gonçalves, EL; Martins, ML; Roumbedakis, K; Scussel, VM1
Conradie, F; Evans, D; Louw, R; Mabaso, S; Mabiletsa, T; Sefoka, M; Van Rie, A1
Tjeerdema, RS; Van Scoy, AR1
HARRIS, DA; PECK, RL; REAGAN, MA; RUGER, M; WALLICK, H; WOLF, FJ; WOODRUFF, HB1
CUCKLER, AC; FROST, BM; McCLELLAND, L; SOLOTOROVSKY, M1
CONZELMAN, GM1
Araújo, Mdo C; Barbosa, NV; Farias, IL; Leitemperger, J; Loro, VL; Menezes, C; Murussi, C; Perazzo, GX; Toni, C1
Darwish, M; El Maataoui, M; Lopez-Lauri, F; Sallanon, H; Urban, L1
González-Sapienza, G; González-Techera, A; Lassabe, G; Rossotti, M1
Alm, RA; Golparian, D; Huband, M; Jacobsson, S; Jensen, JS; Mueller, J; Ohnishi, M; Unemo, M1
Abdelsayed, S; El Hage Chahine, JM; Ha Duong, NT; Hai, J; Hémadi, M; Serradji, N; Verbeke, P1
Corniani, N; Dayan, FE; Nanayakkara, NP; Silva, FM; Velini, ED; Witschel, M1
Carlomagno, M; González-Sapienza, G; González-Techera, A; Lassabe, G; Rossotti, M; Vanrell, L1
Hammerschlag, MR; Huband, MD; Kohlhoff, SA1
Azevedo, RA; Carvalho, G; Dourado, MN; Martins, PF; Peters, LP; Pileggi, M; Vilhena, MB1
Alm, RA; Basarab, GS; Bradford, PA; Giacobbe, RA; Huband, MD; Johnstone, MR; Kutschke, AC; Miller, PF; Mueller, JP; Otterson, LG; Patey, SA; Potter, ME1
Carter, RL; Hay, BA; Hicks, JW; Houle, S; Parkes, J; Sadovski, O; Vasdev, N; Wilson, AA1
Boggs, S; Caravella, JA; Chen, L; Creech, KL; Deaton, DN; Kaldor, I; Parks, DJ; Smalley, TL1
Alm, RA; Gardner, H; Huband, MD; Kutschke, A; Lahiri, SD; Lewis, LA; McLaughlin, RE; Mueller, JP; Otterson, LG; Su, X; Whiteaker, JD1
Alnaser, O; Darwish, M; El Maataoui, M; Junglee, S; Lopez-Lauri, F; Sallanon, H; Vidal, V1
Costa, M; Guerra, L; Leitemperger, J; Lópes, T; Loro, VL; Menezes, C; Murussi, CR; Severo, E; Zanella, R1
Crabb, DM; Duffy, LB; Huband, MD; Waites, KB1
Darwish, M; El Maâtaoui, M; Lopez-Lauri, F; Sallanon, H; Vidal, V1
Cole, M; Fredlund, H; Jacobsson, S; Ringlander, J; Unemo, M; Wiggins, C1
Andrews, B; Basarab, GS; Doig, P; Ehmann, DE; Fan, J; Gao, N; Kern, G; Mills, SD; Mueller, J; Palmer, T; Shapiro, AB; Sriram, S; Thresher, J; Walkup, GK1
Basarab, GS; Doig, P; Galullo, V; Gowravaram, M; Kern, G; Kimzey, A; Kutschke, A; Morningstar, M; Mueller, J; Newman, JP; Otterson, L; Vishwanathan, K; Zhou, F1
Alm, RA; Barvian, K; Basarab, GS; Doig, P; Galullo, V; Gardner, H; Gowravaram, M; Huband, M; Kern, GH; Kimzey, A; Kutschke, A; Lahiri, SD; Lawrence, K; McNulty, J; Morningstar, M; Mueller, JP; Newman, JV; Perros, M; Schuck, VJ; Singh, R; Tommasi, R; Vishwanathan, K; Walkup, G1
Biedenbach, DJ; Bradford, PA; de Jonge, BL; Hackel, M; Huband, MD; Sahm, DF1
Azam, MA; Jubie, S; Thathan, J1
Cao, J; Diao, X; Li, P; Li, QX; Zheng, P1
Butler-Laporte, G; Menzies, D; Winters, N1
Alsleben, N; Donald, PR; Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; Willemse, M1
Alm, RA; Le, WJ; Li, S; Liu, YR; Mueller, JP; Rice, PA; Su, XH; Wan, C; Wang, BX1
Chong, Y; Lee, H; Lee, K1
Abdalla, FC; Costa, MJ; de Oliveira, CR; Fraceto, LF; Rizzi, GM; Salla, RF; Silva-Zacarin, EC1
Chen, L; Song, L; Tong, H; Wang, M; Yu, R; Zhu, J; Zi, J1
Basarab, GS; Grimm, SW; Guo, J; Joubran, C; Luzietti, RA; Vishwanathan, K1
Benincá, C; Freire, FB; Gonçalves, FF; Martins, ML; Vargas, FT; Vargas, RP; Zanoelo, EF1
Busi, R; Chauhan, BS; Nguyen, NK; Powles, SB; Tabacchi, M; Vidotto, F1
Kirkcaldy, RD; Lawrence, K; Mueller, J; Papp, JR; Sharpe, S1
Siwek, H; Włodarczyk, M1
Bradford, PA; deJonge, BL; Giacobbe, RA; Huband, MD1
Ahuja, S; Benedetti, A; Cox, H; Fox, GJ; Koh, WJ; Menzies, D; Pasvol, G; Viiklepp, P1
Cox, L; Gámiz, B; Hermosín, MC; Spokas, KA; Velarde, P1
Alves de Almeida, E; Felício, AA; Freitas, JS; Teresa, FB1
Alffenaar, JWC; Migliori, GB; Peloquin, CA1
Court, R; de Vries, N; Gumbo, T; Harding, J; Maartens, G; McIlleron, H; Stewart, A; Wiesner, L1
de Mello, ÍCMF; Katayama, N; Knauth, DS; Maltchik, L; Pires, MM; Stenert, C1
Damião Gouveia, AC; Jensen, JS; Unemo, M1
Mugabo, P; Mulubwa, M1
Dong, F; Du, P; Liu, X; Wu, X; Xu, J; Zhang, Y; Zheng, Y1
Boulle, A; Fox, T; Khomo, N; Kock, Y; Leslie, J; Manning, K; Meintjes, G; Mudaly, V; Stewart, A; Tiffin, N; Wasserman, S; Zhao, Y1
Bellamacina, C; Benton, BM; Bojkovic, J; Fu, J; Karur, S; Lapointe, G; Lee, PS; Liu, A; Madera, AM; McDowell, L; McKenney, D; Morris, L; Osborne, C; Rico, A; Shu, W; Simmons, RL; Sweeney, ZK; Thompson, K; Tjandra, M; Tonn, GR; Uehara, K; Xie, L; Xu, W; Yifru, A1
Bristow, CC; Cristillo, AD; Dillon, JA; Dong, H; Grad, YH; Kirkcaldy, RD; Klausner, JD; Lawrence, K; Morris, SR; Nicholas, RA; Oldach, D; Rice, PA; Shafer, WM; Torrone, E; Wi, TE; Zhou, P1
Hosagrahara, V; Lawrence, K; Mueller, JP; O'Donnell, J; Vishwanathan, K1
Batteiger, BE; Hook, EW; Johnson, SM; Kwak, H; Lawrence, K; Long, J; Marrazzo, J; Mueller, J; Seña, AC; Taylor, SN; Wierzbicki, MR1
Fenner, A1
Bianchini, MC; da Cruz Pereira, G; Denardin, ELG; Escoto, DF; Gayer, MC; Roehrs, R1
Guo, F; Iwakami, S; Matsumoto, H; Sunohara, Y; Uchino, A; Yamaguchi, T1
Martins Dos Santos, VAP; Rienksma, RA; Schaap, PJ; Suarez-Diez, M1
Lewis, DA1
Alirol, E; Drusano, G; Foerster, S; Golparian, D; Neely, M; Piddock, LJV; Unemo, M1
Albarrán, Á; Fernández, D; Gómez, S; López-Piñeiro, A; Peña, D; Rato-Nunes, JM; Rozas, MÁ1
Al-Khatib, K; Brunharo, CACG; Driver, KE1
Książek, P; Podbielska, M; Szpyrka, E; Słowik-Borowiec, M; Zwolak, A1
Alencar, BTB; Cabral, CM; Coutinho, ÍAC; Ferreira, EA; Francino, DMT; Ribeiro, VHV; Santos, JBD1
Becker, P; Keddy, KH; Lancaster, J; Shean, K; van der Walt, ML1
Kern, WV; Köser, R; Rossen, JWA; Schuster, S; Vavra, M1
Endo, M; Guo, F; Iwakami, S; Matsumoto, H; Sunohara, Y; Uchino, A; Yamaguchi, T1
Aanensen, D; Ahlstrand, J; Cole, MJ; Day, M; Golparian, D; Jacobsson, S; Sánchez-Busó, L; Unemo, M1
Brkić, D; Gašić, S; Mihajlović, V; Stevanović, M; Tomić, T; Đorđević, T1
Centner, CM; Chirehwa, M; Court, R; de Vries, N; Denti, P; Gumbo, T; Harding, J; Maartens, G; McIlleron, H; Wiesner, L1
Cao, J; Dong, F; Liu, X; Rong, L; Wu, X; Xu, H; Xu, J; Zheng, Y1
Hu, J; Liang, Y; Wei, L1
Balyklova, KS; Demkin, NA; Pomerantsev, AL; Rodionova, OY; Titova, AV1
Adamson, PC; Ha, SM; Klausner, JD; Lin, EY1
Cutti, L; Kaspary, TE; Markus, C; Merotto, A; Rigon, CAG; Turra, GM1
Conrad, T; Gu, K; Kankam, M; Mueller, J; Nakamura, A; Newman, LM; O'Donnell, J; Osborn, BL; Saviolakis, GA1
Boileau, I; Gill, T; Houle, S; Hutchison, MG; Jetly, R; Kish, SJ; McCluskey, T; Meyer, JH; Rhind, SG; Richardson, JD; Tong, J; Vasdev, N; Warsh, J; Watling, SE1
Kuang, H; Liu, L; Song, S; Wang, P; Xu, C; Xu, X1

Reviews

8 review(s) available for oxazolidin-2-one and isoxazoles

ArticleYear
Update on medication-induced peripheral neuropathy.
    Current neurology and neuroscience reports, 2009, Volume: 9, Issue:1

    Topics: Acetamides; Anti-Infective Agents; Antibodies, Monoclonal; Antirheumatic Agents; Clinical Trials as Topic; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Isoxazoles; Leflunomide; Linezolid; Oxazolidinones; Peripheral Nervous System Diseases; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

2009
Safety of cycloserine and terizidone for the treatment of drug-resistant tuberculosis: a meta-analysis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2013, Volume: 17, Issue:10

    Topics: Antibiotics, Antitubercular; Central Nervous System Diseases; Cycloserine; Humans; Isoxazoles; Mental Disorders; Oxazolidinones; Tuberculosis, Multidrug-Resistant

2013
Environmental fate and toxicology of clomazone.
    Reviews of environmental contamination and toxicology, 2014, Volume: 229

    Topics: Animals; Herbicides; Humans; Isoxazoles; Oxazolidinones; Photolysis; Volatilization; Water

2014
Dual targeting DNA gyrase B (GyrB) and topoisomerse IV (ParE) inhibitors: A review.
    Bioorganic chemistry, 2015, Volume: 62

    Topics: Amino Acid Sequence; Aminopyridines; Anti-Bacterial Agents; Barbiturates; Benzimidazoles; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Indazoles; Isoxazoles; Morpholines; Organophosphates; Oxazolidinones; Prodrugs; Pyrazoles; Pyrroles; Pyrrolidines; Pyrrolidinones; Quinazolinones; Quinolines; Spiro Compounds; Topoisomerase II Inhibitors; Topoisomerase Inhibitors; Urea

2015
Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment.
    The European respiratory journal, 2015, Volume: 46, Issue:5

    Topics: Amoxicillin; Antitubercular Agents; Azithromycin; Cilastatin; Clarithromycin; Clavulanic Acid; HIV Infections; Humans; Imipenem; Isoxazoles; Macrolides; Meropenem; Mycobacterium tuberculosis; Oxazolidinones; Randomized Controlled Trials as Topic; Thienamycins; Thioridazine; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization

2015
New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae.
    Expert review of anti-infective therapy, 2016, Volume: 14, Issue:2

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Ceftriaxone; Drug Resistance, Bacterial; Drug Therapy, Combination; Gonorrhea; Humans; Isoxazoles; Macrolides; Morpholines; Neisseria gonorrhoeae; Neisseriaceae Infections; Oxazolidinones; Pharyngitis; Spectinomycin; Spiro Compounds; Triazoles

2016
Group 5 drugs for multidrug-resistant tuberculosis: individual patient data meta-analysis.
    The European respiratory journal, 2017, Volume: 49, Issue:1

    Topics: Adult; Amoxicillin; Antitubercular Agents; Clofazimine; Cohort Studies; Drug Therapy, Combination; Female; Humans; Isoxazoles; Linezolid; Logistic Models; Macrolides; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Oxazolidinones; Thioacetazone; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2017
New treatment options for Neisseria gonorrhoeae in the era of emerging antimicrobial resistance.
    Sexual health, 2019, Volume: 16, Issue:5

    Topics: Acenaphthenes; Anti-Bacterial Agents; Barbiturates; Drug Development; Drug Resistance, Multiple, Bacterial; Gonorrhea; Heterocyclic Compounds, 3-Ring; Humans; Isoxazoles; Macrolides; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds; Triazoles

2019

Trials

8 trial(s) available for oxazolidin-2-one and isoxazoles

ArticleYear
[Rezonizat and cycloserine in complex therapy of drug resistant tuberculosis (comparative studies)].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2008, Volume: 53, Issue:11-12

    Topics: Adult; Antibiotics, Antitubercular; Cycloserine; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Middle Aged; Oxazolidinones; Tuberculosis, Multidrug-Resistant; Young Adult

2008
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Antitubercular Agents; Clarithromycin; Cycloserine; Dapsone; Diarylquinolines; Erythromycin; Female; Humans; Isoxazoles; Male; Ofloxacin; Oxazolidinones; Quinolines; Tuberculosis, Multidrug-Resistant

2012
Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
    Scientific reports, 2015, Jul-14, Volume: 5

    Topics: Adult; Animals; Anti-Bacterial Agents; Barbiturates; Disease Models, Animal; DNA Topoisomerases, Type II; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gonorrhea; Haplorhini; Humans; Isoxazoles; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Models, Molecular; Molecular Conformation; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Rats; Spiro Compounds; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase II Inhibitors; Young Adult

2015
Antimicrobial Resistance in Neisseria gonorrhoeae: Proceedings of the STAR Sexually Transmitted Infection-Clinical Trial Group Programmatic Meeting.
    Sexually transmitted diseases, 2019, Volume: 46, Issue:3

    Topics: Anti-Bacterial Agents; Antimicrobial Stewardship; Bacterial Vaccines; Barbiturates; Drug Resistance, Multiple, Bacterial; Epidemiological Monitoring; Gonorrhea; Group Processes; Humans; Isoxazoles; Macrolides; Microbial Sensitivity Tests; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Public Health; Sexually Transmitted Diseases; Spiro Compounds; Topoisomerase Inhibitors; Triazoles; World Health Organization

2019
Single-Dose Pharmacokinetics, Excretion, and Metabolism of Zoliflodacin, a Novel Spiropyrimidinetrione Antibiotic, in Healthy Volunteers.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Barbiturates; Biological Availability; Biotransformation; Drug Administration Schedule; Feces; Female; Gastrointestinal Absorption; Half-Life; Healthy Volunteers; Humans; Isoxazoles; Male; Morpholines; Oxazolidinones; Spiro Compounds

2019
Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea.
    The New England journal of medicine, 2018, 11-08, Volume: 379, Issue:19

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Barbiturates; Ceftriaxone; Female; Female Urogenital Diseases; Gonorrhea; Humans; Injections, Intramuscular; Intention to Treat Analysis; Isoxazoles; Male; Male Urogenital Diseases; Microbial Sensitivity Tests; Middle Aged; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Pharyngeal Diseases; Rectal Diseases; Sexual Partners; Spiro Compounds; Treatment Outcome; Young Adult

2018
High susceptibility to zoliflodacin and conserved target (GyrB) for zoliflodacin among 1209 consecutive clinical Neisseria gonorrhoeae isolates from 25 European countries, 2018.
    The Journal of antimicrobial chemotherapy, 2021, 04-13, Volume: 76, Issue:5

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Europe; Gonorrhea; Humans; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds

2021
Thorough QT Study To Evaluate the Effect of Zoliflodacin, a Novel Therapeutic for Gonorrhea, on Cardiac Repolarization in Healthy Adults.
    Antimicrobial agents and chemotherapy, 2021, 11-17, Volume: 65, Issue:12

    Topics: Adult; Barbiturates; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Fluoroquinolones; Gonorrhea; Healthy Volunteers; Heart Rate; Humans; Isoxazoles; Long QT Syndrome; Morpholines; Oxazolidinones; Spiro Compounds

2021

Other Studies

137 other study(ies) available for oxazolidin-2-one and isoxazoles

ArticleYear
5-Carboxamido-4-amino-3-isoxazolidone, and asparagine analogue.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Isoxazoles; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Oxazolidinones

1978
3-Isoxazolidone--an inhibitor of GABA metabolism.
    Biochemical pharmacology, 1976, Jul-15, Volume: 25, Issue:14

    Topics: Aminobutyrates; Animals; Brain; Chickens; Depression, Chemical; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Isoniazid; Isoxazoles; Male; Mice; Oxazoles; Oxazolidinones; Rats; Seizures; Time Factors

1976
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:11

    Topics: Animals; Bicuculline; Brain; Cats; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Oxazolidinones; Piperidines; Rats; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes

1985
[Urovalidin Bracco in the therapy of urinary tract infections in children].
    Ceskoslovenska pediatrie, 1973, Volume: 28, Issue:8

    Topics: Anesthetics, Local; Anti-Infective Agents, Urinary; Cycloserine; Drug Combinations; Drug Evaluation; Humans; Isoxazoles; Oxazoles; Oxazolidinones; Phenazopyridine; Pyridines; Urinary Tract Infections

1973
Monitoring herbicide leaching in sustainable vegetable culture using tension lysimeters.
    Bulletin of environmental contamination and toxicology, 1995, Volume: 54, Issue:6

    Topics: Chromatography, Gas; Culture Media; Herbicides; Isoxazoles; Kentucky; Oxazolidinones; Solubility; Vegetables; Volatilization; Water Pollutants, Chemical

1995
Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations.
    Molecular pharmacology, 1994, Volume: 46, Issue:5

    Topics: Animals; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Oocytes; Oxazolidinones; Piperidines; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus

1994
Clomazone residues in soil and runoff: measurement and mitigation.
    Bulletin of environmental contamination and toxicology, 2000, Volume: 64, Issue:2

    Topics: Capsicum; Cucurbitaceae; Environmental Monitoring; Herbicides; Isoxazoles; Kentucky; Oxazolidinones; Pesticide Residues; Plants, Medicinal; Soil; Water

2000
Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis.
    Biochemical Society transactions, 2000, Volume: 28, Issue:6

    Topics: Aldose-Ketose Isomerases; Animals; Arabidopsis; Chlamydomonas; Fosfomycin; Herbicides; Hordeum; Isoxazoles; Kinetics; Multienzyme Complexes; Oxazolidinones; Oxidoreductases; Transferases

2000
The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria.
    Biochemical Society transactions, 2000, Volume: 28, Issue:6

    Topics: Anti-Bacterial Agents; Antimalarials; Bacteria; Butadienes; Carotenoids; Chlorophyll; Drug Evaluation, Preclinical; Hemiterpenes; Herbicides; Hordeum; Isoxazoles; Oxazolidinones; Pentanes; Plant Leaves; Plants

2000
Development and validation of a high-performance liquid chromatographic method for the determination of clomazone residues in surface water.
    Journal of chromatography. A, 2000, Dec-29, Volume: 904, Issue:2

    Topics: Calibration; Chromatography, High Pressure Liquid; Isoxazoles; Oxazolidinones; Pesticide Residues; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2000
Laboratory and field studies on the effect of molinate, clomazone, and thiobencarb on nontarget aquatic invertebrates.
    Environmental toxicology and chemistry, 2001, Volume: 20, Issue:10

    Topics: Animals; Azepines; Biometry; Body Constitution; Chironomidae; Dose-Response Relationship, Drug; Herbicides; Invertebrates; Isoxazoles; Larva; Oxazolidinones; Population Dynamics; Sex Factors; Thiocarbamates; Water Pollutants, Chemical; Wings, Animal

2001
Introduction of 4(S)-oxazolidineacetic acid, 2-oxo (D-Oxac) motif in a polypeptide chain: synthesis and conformational analysis.
    Organic & biomolecular chemistry, 2003, Jan-21, Volume: 1, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Oligopeptides; Oxazolidinones; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Stereoisomerism

2003
Study on orientomycin, identified with d-4-amino-3-isoxazolidone. Studies on actinomyces antibiotics. XXXVII.
    The Journal of antibiotics, 1956, Volume: 9, Issue:4

    Topics: Actinomyces; Anti-Bacterial Agents; Isoxazoles; Oxazolidinones

1956
[EEG study of patients of chronic pulmonary tuberculosis during D-4-amino-3-isoxazolidone (cycloserine) therapy].
    Lotta contro la tubercolosi, 1957, Volume: 27, Issue:12

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Cycloserine; Dermatologic Agents; Electroencephalography; Isoxazoles; Oxazolidinones; Tuberculosis; Tuberculosis, Pulmonary

1957
[Studies on pharmacological activity of 1,4-amino-3-isoxazolidone].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Nov-15, Volume: 34, Issue:21

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatologic Agents; Humans; Isoxazoles; Oxazolidinones

1958
[Experimental data on the pre-anesthetic action of 1-4-amino-3-isoxazolidone].
    Il Farmaco; edizione scientifica, 1959, Volume: 14, Issue:5

    Topics: Anesthesia; Anesthesiology; Anesthetics; Anti-Bacterial Agents; Antibiotics, Antitubercular; Isoxazoles; Oxazolidinones

1959
[Analysis of the central actions of L-4-amino-3-isoxazolidone. Electroencephalographic changes in man].
    Archives internationales de pharmacodynamie et de therapie, 1961, Apr-01, Volume: 131

    Topics: Cycloserine; Electroencephalography; Isoxazoles; Oxazolidinones

1961
[Analysis of the sedative effect exerted by 1,4-amino-3-isoxazolidone].
    Archives internationales de pharmacodynamie et de therapie, 1960, Feb-01, Volume: 124

    Topics: Cycloserine; Hypnotics and Sedatives; Isoxazoles; Oxazolidinones

1960
SYNERGISM OF D-4-AMINO-3-ISOXAZOLIDONE AND O-CARBAMYL-D-SERINE.
    The Journal of antibiotics, 1964, Volume: 17

    Topics: Anti-Bacterial Agents; Bacillus subtilis; Isoxazoles; Mycobacterium; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Pharmacology; Research; Serine; Staphylococcus

1964
[BLADDER DISEASE DUE TO RADIUM THERAPY. (CLINICAL EXPERIENCES WITH A NEW ANTIBIOTIC-AZO DYE ASSOCIATION, N4,N4'-TEREPHTHALAL-BIS-(D-4-AMINO-3-ISOXAZOLIDONE) AND 2,6 DIAMINO-3-PHENYLAZO-PYRIDINE HYDROCHLORIDE)].
    Rivista d'ostetricia e ginecologia pratica, 1965, Volume: 47

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Azo Compounds; Coloring Agents; Humans; Isoxazoles; Oxazolidinones; Pyridines; Radiation Injuries; Radium; Urinary Bladder Diseases

1965
[Action of the optical isomers of 4-amino-3-isoxazolidone (cycloserine) and of one of the intermediates in its synthesis (isoxazolidone) on the oxidative metabolism of some strains of Escherichia coli].
    Bollettino della Societa italiana di biologia sperimentale, 1960, May-31, Volume: 36

    Topics: Cell Respiration; Cycloserine; Emotions; Escherichia coli; Isoxazoles; Oxazolidinones

1960
[Action of the optical isomers of 4-amino-3-isoxazolidone (cycloserine) and of one of the intermediates in its synthesis (isoxazolidone) on the oxidative metabolism of some strains of Salmonella and Eberthella].
    Bollettino della Societa italiana di biologia sperimentale, 1960, May-31, Volume: 36

    Topics: Cell Respiration; Cycloserine; Isoxazoles; Oxazolidinones; Salmonella; Salmonella paratyphi A; Salmonella typhi; Sprains and Strains

1960
Light and clomazone effects on tobacco (Nicotiana tabacum) callus and leaf discs.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2003, Volume: 38, Issue:6

    Topics: Herbicides; Humans; Isoxazoles; Nicotiana; Oxazolidinones; Plant Leaves; Sunlight

2003
Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris.
    Planta, 2004, Volume: 218, Issue:5

    Topics: Brassinosteroids; Chlorella; Cholestanols; Darkness; Hemiterpenes; Isoxazoles; Light; Lovastatin; Organophosphorus Compounds; Oxazolidinones; Steroids, Heterocyclic; Triazoles

2004
Investigation of the effect of soil herbicides on the growth and nutrient uptake of potato.
    Communications in agricultural and applied biological sciences, 2003, Volume: 68, Issue:4 Pt A

    Topics: Herbicides; Isoxazoles; Nitrogen; Oxazolidinones; Phenylurea Compounds; Phosphorus; Plant Shoots; Soil; Solanum tuberosum; Species Specificity; Triazines

2003
The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones.
    Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Female; Isoxazoles; Mice; Microbial Sensitivity Tests; Oxazolidinones

2004
Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Isoxazoles; Microbial Sensitivity Tests; Models, Molecular; Nitrogen; Oxazolidinones; Oxazolone; Pyrroles; Stereoisomerism; Structure-Activity Relationship

2004
Clomazone dissipation, adsorption and translocation in four paddy topsoils.
    Journal of environmental sciences (China), 2004, Volume: 16, Issue:4

    Topics: Adsorption; Agriculture; Environmental Monitoring; Isoxazoles; Oryza; Oxazolidinones; Soil; Soil Pollutants

2004
Comparative actions of clomazone on beta-carotene levels and growth in rice (Oryza sativa) and watergrasses (Echinochloa spp).
    Pest management science, 2005, Volume: 61, Issue:6

    Topics: beta Carotene; Dose-Response Relationship, Drug; Echinochloa; Herbicides; Isoxazoles; Oryza; Oxazolidinones

2005
Effects of the herbicides clomazone, quinclorac, and metsulfuron methyl on acetylcholinesterase activity in the silver catfish (Rhamdia quelen) (Heptapteridae).
    Ecotoxicology and environmental safety, 2005, Volume: 61, Issue:3

    Topics: Acetylcholinesterase; Animals; Arylsulfonates; Brain; Catfishes; Herbicides; Isoxazoles; Lethal Dose 50; Muscle, Skeletal; Oryza; Oxazolidinones; Quinolines; Survival; Water Pollutants, Chemical

2005
Effects of clomazone herbicide on hematological and some parameters of protein and carbohydrate metabolism of silver catfish Rhamdia quelen.
    Ecotoxicology and environmental safety, 2006, Volume: 65, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbohydrate Metabolism; Catfishes; Hematocrit; Herbicides; Isoxazoles; Liver; Muscles; Oxazolidinones; Proteins

2006
Heterocyclic ring scaffolds as small-molecule cholesterol absorption inhibitors.
    Organic & biomolecular chemistry, 2005, Oct-07, Volume: 3, Issue:19

    Topics: Anticholesteremic Agents; Azetidines; beta-Lactams; Ezetimibe; Heterocyclic Compounds; Isoxazoles; Molecular Structure; Oxazolidinones; Pyrazoles; Stereoisomerism

2005
Field dissipation and environmental hazard assessment of clomazone, molinate, and thiobencarb in Australian rice culture.
    Journal of agricultural and food chemistry, 2006, Sep-20, Volume: 54, Issue:19

    Topics: Azepines; Environmental Pollution; Herbicides; Isoxazoles; New South Wales; Oryza; Oxazolidinones; Seeds; Soil; Thiocarbamates; Water

2006
Effect of clomazone herbicide on biochemical and histological aspects of silver catfish (Rhamdia quelen) and recovery pattern.
    Chemosphere, 2007, Volume: 67, Issue:11

    Topics: Acetylcholinesterase; Agriculture; Animals; Brain; Catalase; Female; Fishes; Herbicides; Isoxazoles; Liver; Male; Muscle, Skeletal; Oryza; Oxazolidinones; Thiobarbituric Acid Reactive Substances

2007
The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia: presence and sensitivity to fosmidomycin.
    Experimental parasitology, 2007, Volume: 116, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Chickens; Coccidia; Cryptosporidium; Cryptosporidium parvum; Eimeria tenella; Erythritol; Fosfomycin; Gene Expression Regulation, Developmental; Genome, Protozoan; Herbicides; Isoxazoles; Mice; Mice, Inbred CBA; Oxazolidinones; Terpenes; Toxoplasma

2007
Burned rice straw reduces the availability of clomazone to barnyardgrass.
    The Science of the total environment, 2008, Mar-25, Volume: 392, Issue:2-3

    Topics: Adsorption; Echinochloa; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Seedlings

2008
Responses to clomazone and 5-ketoclomazone by Echinochloa phyllopogon resistant to multiple herbicides in Californian rice fields.
    Pest management science, 2008, Volume: 64, Issue:10

    Topics: Biomass; California; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfoton; Echinochloa; Enzyme Inhibitors; Herbicide Resistance; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Paraquat; Pigments, Biological

2008
Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:3

    Topics: Cell Line; HIV-1; Humans; Isoxazoles; Magnetic Resonance Spectroscopy; Oxazolidinones; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared

2009
Biochemical effects of clomazone herbicide on piava (Leporinus obtusidens).
    Chemosphere, 2008, Volume: 74, Issue:1

    Topics: Acetylcholinesterase; Animals; Catalase; Fishes; Herbicides; Isoxazoles; Liver; Muscles; Oxazolidinones; Protein Carbonylation; Thiobarbituric Acid Reactive Substances

2008
Natural impacted freshwaters: in situ use of alginate immobilized algae to the assessment of algal response.
    Ecotoxicology (London, England), 2009, Volume: 18, Issue:4

    Topics: Alginates; Brazil; Carbofuran; Environmental Monitoring; Eukaryota; Fresh Water; Glucuronic Acid; Hexuronic Acids; Isoxazoles; Oxazolidinones; Toxicity Tests; Water Pollutants, Chemical

2009
The behavior of clomazone in the soil environment.
    Pest management science, 2009, Volume: 65, Issue:6

    Topics: Adsorption; Herbicides; Humic Substances; Isoxazoles; Oxazolidinones; Soil

2009
Microbial degradation of clomazone under simulated California rice field conditions.
    Journal of agricultural and food chemistry, 2010, Mar-24, Volume: 58, Issue:6

    Topics: Biodegradation, Environmental; California; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Soil Microbiology; Soil Pollutants

2010
Differential oxidative metabolism and 5-ketoclomazone accumulation are involved in Echinochloa phyllopogon resistance to clomazone.
    Plant physiology, 2010, Volume: 153, Issue:1

    Topics: Chromatography, Liquid; Echinochloa; Herbicide Resistance; Herbicides; Isoxazoles; Oxazolidinones; Oxidation-Reduction; Tandem Mass Spectrometry

2010
A clomazone immunoassay to study the environmental fate of the herbicide in rice (Oryza sativa) agriculture.
    Journal of agricultural and food chemistry, 2010, Apr-14, Volume: 58, Issue:7

    Topics: Agriculture; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Herbicides; Isoxazoles; Oryza; Oxazolidinones

2010
Validation of method for determination of different classes of pesticides in aqueous samples by dispersive liquid-liquid microextraction with liquid chromatography-tandem mass spectrometric detection.
    Analytica chimica acta, 2010, Apr-14, Volume: 665, Issue:1

    Topics: Carbofuran; Chemical Fractionation; Chromatography, High Pressure Liquid; Isoxazoles; Oxazolidinones; Pesticides; Tandem Mass Spectrometry; Triazoles; Water; Water Pollutants, Chemical

2010
The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae.
    The Journal of antibiotics, 2010, Volume: 63, Issue:10

    Topics: Anti-Bacterial Agents; Binding Sites; Drug Delivery Systems; Enzyme Inhibitors; Erythritol; Escherichia coli; Haemophilus influenzae; Herbicides; Isoxazoles; Microbial Sensitivity Tests; Oxazolidinones; Protein Binding; Sugar Phosphates; Transferases

2010
Bitter pills for drug companies.
    BMJ (Clinical research ed.), 2010, Sep-17, Volume: 341

    Topics: Acetamides; Drug Approval; Drug Industry; Fraud; gamma-Aminobutyric Acid; Isoxazoles; Linezolid; Motivation; Off-Label Use; Oxazolidinones; Piperazines; Pregabalin; Sulfonamides; Thiazoles; United States

2010
Phage anti-immunocomplex assay for clomazone: two-site recognition increasing assay specificity and facilitating adaptation into an on-site format.
    Analytical chemistry, 2010, Nov-01, Volume: 82, Issue:21

    Topics: Animals; Antibodies, Monoclonal; Bacteriophage M13; Female; Herbicides; Immunoassay; Isoxazoles; Limit of Detection; Mice; Mice, Inbred BALB C; Oxazolidinones; Peptide Library; Water Pollutants, Chemical

2010
Terizidone.
    The Journal of the Association of Physicians of India, 2010, Volume: 58

    Topics: Antitubercular Agents; Humans; Isoxazoles; Mycobacterium tuberculosis; Oxazolidinones; Tuberculosis; Tuberculosis, Multidrug-Resistant

2010
Degradation of the herbicides clomazone, paraquat, and glyphosate by thermally activated peroxydisulfate.
    Journal of agricultural and food chemistry, 2010, Dec-22, Volume: 58, Issue:24

    Topics: Environmental Restoration and Remediation; Glycine; Glyphosate; Herbicides; Hot Temperature; Isoxazoles; Kinetics; Oxazolidinones; Oxidation-Reduction; Paraquat; Sodium Compounds; Sulfates

2010
Mitigation of dimethazone residues in soil and runoff water from agricultural field.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2011, Volume: 46, Issue:1

    Topics: Agriculture; Environmental Restoration and Remediation; Gas Chromatography-Mass Spectrometry; Half-Life; Herbicides; Isoxazoles; Oxazolidinones; Pesticide Residues; Sewage; Soil; Soil Pollutants; Water Pollutants, Chemical

2011
Determination of clomazone residues in soybean and soil by high performance liquid chromatography with DAD detection.
    Bulletin of environmental contamination and toxicology, 2011, Volume: 86, Issue:4

    Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Glycine max; Herbicides; Isoxazoles; Oxazolidinones; Pesticide Residues; Soil; Soil Pollutants; Solid Phase Extraction

2011
Tissue biochemical alterations of Cyprinus carpio exposed to commercial herbicide containing clomazone under rice-field conditions.
    Archives of environmental contamination and toxicology, 2012, Volume: 62, Issue:1

    Topics: Acetylcholinesterase; Agriculture; Animals; Carps; Environmental Monitoring; Female; Herbicides; Isoxazoles; Lipid Peroxidation; Liver; Male; Muscle, Skeletal; Oryza; Oxazolidinones; Oxidative Stress; Time Factors; Water Pollutants, Chemical

2012
Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.
    Talanta, 2011, Sep-15, Volume: 85, Issue:3

    Topics: Acetamides; Aminoimidazole Carboxamide; Animals; Benzimidazoles; Carbamates; Chemical Fractionation; Chromatography, Liquid; Environmental Monitoring; Fishes; Geologic Sediments; Hydantoins; Isoxazoles; Methacrylates; Muscles; Naphthalenes; Niacinamide; Oxazolidinones; Pesticide Residues; Pesticides; Phenylurea Compounds; Propionates; Pyrimidines; Quinoxalines; Reproducibility of Results; Solid Phase Extraction; Strobilurins; Sulfonylurea Compounds; Tandem Mass Spectrometry; Thiophenes; Water Pollutants, Chemical

2011
[Efficacy and tolerance of rezonizate in complex with fluoroquinolones or mycobutin on a model of experimental murine tuberculosis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:7-8

    Topics: Animals; Antibiotics, Antitubercular; Disease Models, Animal; Drug Therapy, Combination; Drug Tolerance; Fluoroquinolones; Gatifloxacin; Isoxazoles; Levofloxacin; Mice; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Rifabutin; Tuberculosis

2011
Photolytic versus microbial degradation of clomazone in a flooded California rice field soil.
    Pest management science, 2012, Volume: 68, Issue:8

    Topics: Bacteria; California; Floods; Herbicides; Isoxazoles; Kinetics; Light; Molecular Structure; Oryza; Oxazolidinones; Photolysis; Soil Microbiology

2012
On-farm bioremediation of dimethazone and trifluralin residues in runoff water from an agricultural field.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2012, Volume: 47, Issue:7

    Topics: Agriculture; Bacteria; Biodegradation, Environmental; Environmental Monitoring; Herbicides; Isoxazoles; Oxazolidinones; Pesticide Residues; Soil Pollutants; Trifluralin; Water Pollutants, Chemical

2012
Novel cardiovascular drugs in clinical trials.
    Indian journal of medical sciences, 2010, Volume: 64, Issue:6

    Topics: Anticholesteremic Agents; Benzaldehydes; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Endothelin Receptor Antagonists; Fibrinolytic Agents; Humans; Immunologic Factors; Isoxazoles; Lipoxygenase Inhibitors; Metalloendopeptidases; Oxazolidinones; Oximes; Phospholipase A2 Inhibitors; Probucol; Pyrimidines; Quinolines; Thiophenes

2010
Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout.
    Analytical chemistry, 2013, Jan-15, Volume: 85, Issue:2

    Topics: Azepines; Isoxazoles; Molecular Structure; Nanotechnology; Oxazolidinones; Thiocarbamates

2013
Novel conformationally constrained analogues of agomelatine as new melatoninergic ligands.
    Molecules (Basel, Switzerland), 2012, Dec-24, Volume: 18, Issue:1

    Topics: Acetamides; Animals; CHO Cells; Cricetinae; Isoxazoles; Ligands; Oxazolidinones; Pyrrolidinones; Radioligand Assay; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Structure-Activity Relationship; Tetrazoles; Thiazoles

2012
Biodegradation of clomazone in a California rice field soil: carbon allocation and community effects.
    Journal of agricultural and food chemistry, 2013, Mar-20, Volume: 61, Issue:11

    Topics: Actinobacteria; Biodegradation, Environmental; California; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Soil Microbiology; Soil Pollutants

2013
Hematological and biochemical alterations in the fish Prochilodus lineatus caused by the herbicide clomazone.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:1

    Topics: Acetylcholinesterase; Animals; Brain; Catalase; Characiformes; Erythrocyte Indices; Glutathione Peroxidase; Glutathione Transferase; Hematocrit; Hemoglobins; Herbicides; Isoxazoles; Liver; Oxazolidinones

2013
Serious treatment related adverse drug reactions amongst anti-retroviral naïve MDR-TB patients.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Antitubercular Agents; Coinfection; Cycloserine; Drug Resistance, Multiple, Bacterial; Female; Hearing Loss; HIV Infections; Humans; Isoxazoles; Male; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Oxazolidinones; Prospective Studies; Psychoses, Substance-Induced; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2013
Enzyme inhibitor studies reveal complex control of methyl-D-erythritol 4-phosphate (MEP) pathway enzyme expression in Catharanthus roseus.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Catharanthus; Chloroplasts; Cloning, Molecular; Cycloheximide; DNA, Complementary; Enzyme Inhibitors; Erythritol; Fosfomycin; Gene Expression; Gene Expression Regulation, Plant; Herbicides; Isoenzymes; Isoxazoles; Metabolic Networks and Pathways; Organ Specificity; Oxazolidinones; Paraquat; Plant Leaves; Plant Proteins; Plant Roots; Promoter Regions, Genetic; Proteolysis; Sugar Phosphates; Transferases

2013
A vortex-assisted MSPD method for the extraction of pesticide residues from fish liver and crab hepatopancreas with determination by GC-MS.
    Talanta, 2013, Aug-15, Volume: 112

    Topics: Animals; Atrazine; Brachyura; Dimethoate; Environmental Monitoring; Fenitrothion; Gas Chromatography-Mass Spectrometry; Hepatopancreas; Isoxazoles; Liver; Malathion; Oxazolidinones; Perciformes; Pesticide Residues; Pyrazoles; Reproducibility of Results; Triazoles

2013
Photocatalytic degradation of the herbicide clomazone in natural water using TiO2: kinetics, mechanism, and toxicity of degradation products.
    Chemosphere, 2013, Volume: 93, Issue:1

    Topics: Animals; Catalysis; Cell Line; Cell Proliferation; Environmental Pollutants; Herbicides; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kinetics; Minerals; Oxazolidinones; Photochemical Processes; Rats; Titanium; Water; Water Quality

2013
Combined technology for clomazone herbicide wastewater treatment: three-dimensional packed-bed electrochemical oxidation and biological contact degradation.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2013, Volume: 68, Issue:1

    Topics: Biodegradation, Environmental; Electrochemistry; Herbicides; Isoxazoles; Oxazolidinones; Waste Disposal, Fluid; Water Pollutants, Chemical

2013
Effects of lovastatin, clomazone and methyl jasmonate treatment on the accumulation of purpurin and mollugin in cell suspension cultures of Rubia cordifolia.
    Chinese journal of natural medicines, 2013, Volume: 11, Issue:4

    Topics: Acetates; Anthraquinones; Cell Culture Techniques; Cells, Cultured; Cyclopentanes; Isoxazoles; Lovastatin; Oxazolidinones; Oxylipins; Pyrans; Rubia

2013
Comparative study on effects of dietary with diphenyl diselenide on oxidative stress in carp (Cyprinus carpio) and silver catfish (Rhamdia sp.) exposed to herbicide clomazone.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: Animal Feed; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Carps; Catalase; Catfishes; Diet; Dietary Supplements; Gills; Glutathione Peroxidase; Glutathione Transferase; Herbicides; Isoxazoles; Liver; Muscles; Organoselenium Compounds; Oxazolidinones; Oxidative Stress; Protein Carbonylation; Species Specificity; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Water Pollutants, Chemical

2013
Hematological and histopathological changes in silver catfish Rhamdia quelen (Siluriformes) exposed to clomazone herbicide in the Madre River, Santa Catarina State, Southern Brazil.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2014, Volume: 49, Issue:3

    Topics: Animals; Brazil; Catfishes; Environmental Exposure; Gills; Hematology; Herbicides; Histology; Isoxazoles; Liver; Oxazolidinones; Rivers; Water Pollutants, Chemical

2014
Prevalence and incidence of symmetrical symptomatic peripheral neuropathy in patients with multidrug-resistant TB.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2013, Oct-11, Volume: 104, Issue:1

    Topics: Humans; Incidence; Isoniazid; Isoxazoles; Oxazolidinones; Peripheral Nervous System Diseases; Prevalence; Tuberculosis, Multidrug-Resistant

2013
Discovery, development, and antimicrobial properties of D-4-amino-3-isoxazolidone (oxamycin), a new antibiotic produced by Streptomyces garyphalus n. sp.
    Antibiotics & chemotherapy (Northfield, Ill.), 1955, Volume: 5, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cycloserine; Dermatologic Agents; Isoxazoles; Oxazolidinones; Streptomyces

1955
The antimicrobial evaluation of oxamycin (D-4-amino-3-isoxazolidone), a new broad-spectrum antibiotic.
    Antibiotics & chemotherapy (Northfield, Ill.), 1955, Volume: 5, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cycloserine; Dermatologic Agents; Humans; Isoxazoles; Oxazolidinones

1955
Excretion and metabolism of D-4-amino-3-isoxazolidone (cycloserine) by the Rhesus monkey.
    Antibiotics & chemotherapy (Northfield, Ill.), 1955, Volume: 5, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Body Fluids; Cycloserine; Isoxazoles; Macaca mulatta; Oxazolidinones; Urine

1955
Herbicide clomazone effects on δ-aminolevulinic acid activity and metabolic parameters in Cyprinus carpio.
    Bulletin of environmental contamination and toxicology, 2014, Volume: 92, Issue:4

    Topics: Aminolevulinic Acid; Animals; Carps; Herbicides; Isoxazoles; Oxazolidinones; Water Pollutants, Chemical

2014
Pretreatment with alternation of light/dark periods improves the tolerance of tobacco (Nicotiana tabacum) to clomazone herbicide.
    Journal of photochemistry and photobiology. B, Biology, 2014, May-05, Volume: 134

    Topics: Ascorbate Peroxidases; Carotenoids; Chlorophyll; Glutathione Reductase; Herbicides; Hydrogen Peroxide; Isoxazoles; Light; NADH, NADPH Oxidoreductases; Nicotiana; Oxazolidinones; Oxidoreductases; Photosynthesis; Photosystem II Protein Complex

2014
Shiga-like toxin B subunit of Escherichia coli as scaffold for high-avidity display of anti-immunocomplex peptides.
    Analytical chemistry, 2014, Jun-03, Volume: 86, Issue:11

    Topics: Azepines; Enzyme-Linked Immunosorbent Assay; Herbicides; Immunotoxins; Isoxazoles; Mutagenesis; Oxazolidinones; Peptides; Protein Conformation; Shiga Toxin; Shiga Toxins; Shiga-Toxigenic Escherichia coli; Thiocarbamates; Viral Fusion Proteins; Water Pollutants, Chemical

2014
High in vitro activity of the novel spiropyrimidinetrione AZD0914, a DNA gyrase inhibitor, against multidrug-resistant Neisseria gonorrhoeae isolates suggests a new effective option for oral treatment of gonorrhea.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9

    Topics: Anti-Bacterial Agents; Barbiturates; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Gonorrhea; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds; Topoisomerase II Inhibitors

2014
Design and synthesis of 3-isoxazolidone derivatives as new Chlamydia trachomatis inhibitors.
    Bioorganic & medicinal chemistry letters, 2014, Aug-15, Volume: 24, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Chlamydia trachomatis; Dose-Response Relationship, Drug; Drug Design; HeLa Cells; Humans; Isoxazoles; Mice; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Structure-Activity Relationship

2014
Novel bioassay for the discovery of inhibitors of the 2-C-methyl-D-erythritol 4-phosphate (MEP) and terpenoid pathways leading to carotenoid biosynthesis.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Biological Assay; Biosynthetic Pathways; Carotenoids; Dose-Response Relationship, Drug; Drug Discovery; Erythritol; Herbicides; Hordeum; Isoxazoles; Oxazolidinones; Sugar Phosphates

2014
Recombinant streptavidin nanopeptamer anti-immunocomplex assay for noncompetitive detection of small analytes.
    Analytical chemistry, 2014, Oct-21, Volume: 86, Issue:20

    Topics: Aptamers, Peptide; Chemistry Techniques, Analytical; Herbicides; Immunoassay; Isoxazoles; Limit of Detection; Oryza; Oxazolidinones; Protein Folding; Recombinant Proteins; Streptavidin

2014
In vitro activity of AZD0914, a novel DNA gyrase inhibitor, against Chlamydia trachomatis and Chlamydia pneumoniae.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Chlamydia trachomatis; Chlamydophila pneumoniae; DNA Gyrase; Doxycycline; Isoxazoles; Levofloxacin; Microbial Sensitivity Tests; Morpholines; Oxazolidinones; Spiro Compounds; Topoisomerase II Inhibitors

2014
Differential responses of the antioxidant system of ametryn and clomazone tolerant bacteria.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Antioxidants; Catalase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Isoxazoles; Lipid Peroxidation; Oxazolidinones; Oxidative Stress; Phylogeny; Pseudomonas; Reactive Oxygen Species; RNA, Ribosomal, 16S; Soil Microbiology; Soil Pollutants; Superoxide Dismutase; Triazines

2014
In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Anti-Bacterial Agents; Atypical Bacterial Forms; Barbiturates; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Nucleic Acid Synthesis Inhibitors; Oxazolidinones; Spiro Compounds; Topoisomerase II Inhibitors

2015
Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET.
    Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2

    Topics: Animals; Brain; Fluorine Radioisotopes; Isoxazoles; Male; Models, Molecular; Molecular Structure; Monoamine Oxidase; Oxazolidinones; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tissue Distribution

2015
Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists.
    Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2

    Topics: Drug Evaluation, Preclinical; Fluorescence Resonance Energy Transfer; Humans; Isoxazoles; Models, Molecular; Molecular Structure; Oxazolidinones; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2015
Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:3

    Topics: Barbiturates; DNA Gyrase; Drug Resistance, Bacterial; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds; Topoisomerase II Inhibitors

2015
Tolerance to clomazone herbicide is linked to the state of LHC, PQ-pool and ROS detoxification in tobacco (Nicotiana tabacum L.).
    Journal of plant physiology, 2015, Mar-01, Volume: 175

    Topics: Antioxidants; Apoptosis; Carotenoids; Chlorophyll; Chlorophyll A; Chloroplasts; Electron Transport; Herbicides; Isoxazoles; Light-Harvesting Protein Complexes; Nicotiana; Oxazolidinones; Oxidation-Reduction; Oxygen; Photosynthesis; Photosystem II Protein Complex; Plant Leaves; Plastoquinone; Reactive Oxygen Species; Seedlings

2015
Integrated assessment of biomarker response in carp (Cyprinus carpio) and silver catfish (Rhamdia quelen) exposed to clomazone.
    Archives of environmental contamination and toxicology, 2015, Volume: 68, Issue:4

    Topics: Acetylcholinesterase; Animals; Biomarkers; Carps; Catalase; Catfishes; Glutathione Transferase; Herbicides; Isoxazoles; Oxazolidinones; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Water Pollutants, Chemical

2015
In vitro antibacterial activity of AZD0914 against human Mycoplasmas and Ureaplasmas.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Doxycycline; Humans; Isoxazoles; Levofloxacin; Microbial Sensitivity Tests; Morpholines; Mycoplasma; Mycoplasma genitalium; Mycoplasma pneumoniae; Oxazolidinones; Spiro Compounds; Ureaplasma

2015
Alternation of light/dark period priming enhances clomazone tolerance by increasing the levels of ascorbate and phenolic compounds and ROS detoxification in tobacco (Nicotiana tabacum L.) plantlets.
    Journal of photochemistry and photobiology. B, Biology, 2015, Volume: 148

    Topics: Ascorbic Acid; Autophagy; Carbon Dioxide; Chlorophyll; Chloroplasts; Gases; Hydrogen Peroxide; Isoxazoles; Light; Nicotiana; Oxazolidinones; Phenols; Photosynthesis; Plant Leaves; Reactive Oxygen Species

2015
High in vitro susceptibility to the novel spiropyrimidinetrione ETX0914 (AZD0914) among 873 contemporary clinical Neisseria gonorrhoeae isolates from 21 European countries from 2012 to 2014.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Cefixime; Ceftriaxone; Ciprofloxacin; Drug Resistance, Bacterial; Europe; Fluoroquinolones; Humans; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds

2015
Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: Anti-Bacterial Agents; Barbiturates; Ciprofloxacin; Clinical Trials as Topic; DNA; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; Gene Expression; Humans; Isoxazoles; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Species Specificity; Spiro Compounds; Topoisomerase II Inhibitors

2015
Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914).
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Animals; Cell Line; Crystallography, X-Ray; Dogs; Drug Discovery; Humans; Isoxazoles; Male; Oxazolidinones; Pyrimidines; Rats; Structure-Activity Relationship; Topoisomerase II Inhibitors

2015
In Vitro Activity of AZD0914, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor, against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Anti-Infective Agents; Barbiturates; DNA Gyrase; DNA Topoisomerase IV; Gram-Negative Bacteria; Gram-Positive Bacteria; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Oxazolidinones; Spiro Compounds

2015
Bioaccumulation and Elimination of the Herbicide Clomazone in the Earthworms Eisenia fetida.
    Bulletin of environmental contamination and toxicology, 2015, Volume: 95, Issue:5

    Topics: Animals; Biodegradation, Environmental; Herbicides; Isoxazoles; Lethal Dose 50; Oligochaeta; Oxazolidinones; Pesticide Residues; Soil; Soil Pollutants; Toxicity Tests, Acute

2015
Successful Treatment of a Child With Extensively Drug-Resistant Tuberculous Meningitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:3

    Topics: Anti-Inflammatory Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Hypothyroidism; Isoxazoles; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Prednisolone; Treatment Outcome; Tuberculosis, Meningeal

2015
Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914).
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Anti-Bacterial Agents; Azithromycin; Barbiturates; Ceftriaxone; Ciprofloxacin; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Gene Expression; Gonorrhea; Humans; Isoxazoles; Male; Microbial Sensitivity Tests; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds; Tetracycline; Topoisomerase II Inhibitors; Urethritis

2016
Hepatic effects of the clomazone herbicide in both its free form and associated with chitosan-alginate nanoparticles in bullfrog tadpoles.
    Chemosphere, 2016, Volume: 149

    Topics: Alginates; Animals; Chitosan; Glucuronic Acid; Herbicides; Hexuronic Acids; Isoxazoles; Larva; Liver; Male; Nanoparticles; Oxazolidinones; Rana catesbeiana; Toxicity Tests

2016
Effect of Enzyme Inhibitors on Terpene Trilactones Biosynthesis and Gene Expression Profiling in Ginkgo biloba Cultured Cells.
    Natural product communications, 2015, Volume: 10, Issue:12

    Topics: Enzyme Inhibitors; Gene Expression Regulation, Plant; Ginkgo biloba; Isoxazoles; Lactones; Lovastatin; Oxazolidinones; Transcriptome

2015
Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents.
    Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:1

    Topics: Animals; Barbiturates; DNA Topoisomerases, Type II; Dogs; Humans; Isoxazoles; Mice; Morpholines; Oxazolidinones; Rats; Spiro Compounds; Topoisomerase Inhibitors

2017
Removal of clomazone herbicide from a synthetic effluent by electrocoagulation.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2016, Volume: 73, Issue:12

    Topics: Aluminum; Electricity; Electrodes; Herbicides; Isoxazoles; Oxazolidinones; Waste Disposal, Fluid; Water Pollutants, Chemical

2016
Can herbicide safeners allow selective control of weedy rice infesting rice crops?
    Pest management science, 2017, Volume: 73, Issue:1

    Topics: Crops, Agricultural; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Plant Weeds; Seeds; Triallate; Weed Control

2017
In vitro growth of multidrug-resistant Neisseria gonorrhoeae isolates is inhibited by ETX0914, a novel spiropyrimidinetrione.
    International journal of antimicrobial agents, 2016, Volume: 48, Issue:3

    Topics: Anti-Bacterial Agents; Barbiturates; Drug Resistance, Multiple, Bacterial; Gonorrhea; Humans; Isoxazoles; Male; Microbial Sensitivity Tests; Morpholines; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds; United States; Urethritis

2016
Influence of Formulation on Mobility of Clomazone in Soil.
    Bulletin of environmental contamination and toxicology, 2016, Volume: 97, Issue:4

    Topics: Alginates; Diffusion; Drug Compounding; Glucuronic Acid; Herbicides; Hexuronic Acids; Isoxazoles; Oxazolidinones; Soil; Soil Pollutants; Water

2016
Effect of Susceptibility Testing Conditions on the In Vitro Antibacterial Activity of ETX0914.
    Diagnostic microbiology and infectious disease, 2017, Volume: 87, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Barbiturates; Culture Media; Humans; Hydrogen-Ion Concentration; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Oxazolidinones; Reproducibility of Results; Spiro Compounds; Temperature

2017
Biochar Soil Additions Affect Herbicide Fate: Importance of Application Timing and Feedstock Species.
    Journal of agricultural and food chemistry, 2017, Apr-19, Volume: 65, Issue:15

    Topics: Adsorption; Benzoates; Charcoal; Herbicides; Isoxazoles; Oxazolidinones; Pyrimidines; Soil; Soil Pollutants; Temperature; Time Factors

2017
Combined effects of temperature and clomazone (Gamit
    Chemosphere, 2017, Volume: 185

    Topics: Acetylcholinesterase; Animals; Antioxidants; Anura; Bufonidae; Carboxylesterase; Catalase; Esterases; Glutathione Transferase; Herbicides; Isoxazoles; Larva; Lipid Peroxidation; Oxazolidinones; Oxidative Stress; Superoxide Dismutase; Temperature; Toxicity Tests

2017
Making optimal use of available anti-tuberculosis drugs: first steps to investigate terizidone.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 01-01, Volume: 22, Issue:1

    Topics: Antitubercular Agents; Cycloserine; Humans; Isoxazoles; Oxazolidinones; Tuberculosis; Tuberculosis, Multidrug-Resistant

2018
Steady state pharmacokinetics of cycloserine in patients on terizidone for multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 01-01, Volume: 22, Issue:1

    Topics: Adult; Antitubercular Agents; Area Under Curve; Chromatography, Liquid; Cycloserine; Female; HIV Infections; Humans; Isoxazoles; Male; Middle Aged; Oxazolidinones; Prospective Studies; Regression Analysis; South Africa; Tandem Mass Spectrometry; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2018
Responses of macroinvertebrate communities to pesticide application in irrigated rice fields.
    Environmental monitoring and assessment, 2018, Jan-10, Volume: 190, Issue:2

    Topics: Agricultural Irrigation; Animals; Benzoates; Environmental Monitoring; Herbicides; Insecticides; Invertebrates; Isoxazoles; ortho-Aminobenzoates; Oryza; Oxazolidinones; Pyrimidines

2018
In vitro activity of zoliflodacin (ETX0914) against macrolide-resistant, fluoroquinolone-resistant and antimicrobial-susceptible Mycoplasma genitalium strains.
    The Journal of antimicrobial chemotherapy, 2018, 05-01, Volume: 73, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Barbiturates; Chlorocebus aethiops; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Mycoplasma genitalium; Oxazolidinones; Real-Time Polymerase Chain Reaction; Spiro Compounds; Vero Cells

2018
Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.
    Biomedical chromatography : BMC, 2018, Volume: 32, Issue:11

    Topics: Chromatography, High Pressure Liquid; Humans; Isoxazoles; Limit of Detection; Linear Models; Oxazolidinones; Reproducibility of Results; Tandem Mass Spectrometry

2018
Clomazone influence soil microbial community and soil nitrogen cycling.
    The Science of the total environment, 2018, Dec-10, Volume: 644

    Topics: Ammonia; Archaea; China; Environmental Monitoring; Herbicides; Isoxazoles; Nitrogen; Oxazolidinones; Oxidation-Reduction; Soil; Soil Microbiology

2018
Improved Treatment Outcomes With Bedaquiline When Substituted for Second-line Injectable Agents in Multidrug-resistant Tuberculosis: A Retrospective Cohort Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 04-24, Volume: 68, Issue:9

    Topics: Adult; Antitubercular Agents; Coinfection; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; HIV; HIV Infections; Humans; Isoniazid; Isoxazoles; Levofloxacin; Male; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Retrospective Studies; South Africa; Survival Analysis; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2019
Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.
    Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20

    Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Isoxazoles; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Oxazolidinones

2018
Efficacy of a novel single-dose oral antibiotic for urogenital gonorrhoea.
    Nature reviews. Urology, 2019, Volume: 16, Issue:2

    Topics: Anti-Bacterial Agents; Barbiturates; Gonorrhea; Humans; Isoxazoles; Morpholines; Oxazolidinones; Spiro Compounds

2019
Use of Pistia stratiotes for phytoremediation of water resources contaminated by clomazone.
    Chemosphere, 2019, Volume: 227

    Topics: Araceae; Biodegradation, Environmental; Drug Tolerance; Herbicides; Isoxazoles; Oxazolidinones; Water Pollutants, Chemical; Water Resources

2019
Role of CYP81A cytochrome P450s in clomazone metabolism in Echinochloa phyllopogon.
    Plant science : an international journal of experimental plant biology, 2019, Volume: 283

    Topics: Arabidopsis; Cytochrome P-450 Enzyme System; Echinochloa; Herbicide Resistance; Herbicides; Isoxazoles; Oxazolidinones; Plant Proteins; Plants, Genetically Modified; Real-Time Polymerase Chain Reaction

2019
Modeling Host-Pathogen Interaction to Elucidate the Metabolic Drug Response of Intracellular
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Adenosine Triphosphatases; Amides; Amino Acids; Antitubercular Agents; Cycloserine; Diarylquinolines; Drug Tolerance; Ethambutol; Ethionamide; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Host-Pathogen Interactions; Humans; Isoniazid; Isoxazoles; Metabolic Networks and Pathways; Models, Biological; Mycobacterium bovis; Mycobacterium tuberculosis; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis

2019
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant antimicrobials for Neisseria gonorrhoeae.
    The Journal of antimicrobial chemotherapy, 2019, 12-01, Volume: 74, Issue:12

    Topics: Anti-Bacterial Agents; Barbiturates; Drug Resistance, Bacterial; Drug Synergism; Isoxazoles; Microbial Sensitivity Tests; Models, Theoretical; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds

2019
How the environmental fate of clomazone in rice fields is influenced by amendment with olive-mill waste under different regimes of irrigation and tillage.
    Pest management science, 2020, Volume: 76, Issue:5

    Topics: Agriculture; Isoxazoles; Olea; Oryza; Oxazolidinones; Soil; Soil Pollutants

2020
Mechanism of clomazone resistance in Leptochloa fusca spp. fasicularis to clomazone.
    Pesticide biochemistry and physiology, 2020, Volume: 162

    Topics: California; Herbicide Resistance; Herbicides; Isoxazoles; Oryza; Oxazolidinones; Tandem Mass Spectrometry

2020
The difference in dissipation of clomazone and metazachlor in soil under field and laboratory conditions and their uptake by plants.
    Scientific reports, 2020, 02-28, Volume: 10, Issue:1

    Topics: Acetamides; Brassica napus; Isoxazoles; Models, Biological; Oxazolidinones; Soil

2020
Morphoanatomical injuries in Pistia stratiotes L. (Araceae) as a result of exposure to clomazone in water.
    Anais da Academia Brasileira de Ciencias, 2020, Volume: 92 Suppl 1

    Topics: Araceae; Herbicides; Isoxazoles; Oxazolidinones; Pesticide Residues; Water Pollutants, Chemical

2020
Treatment Outcomes and Adverse Drug Effects of Ethambutol, Cycloserine, and Terizidone for the Treatment of Multidrug-Resistant Tuberculosis in South Africa.
    Antimicrobial agents and chemotherapy, 2020, 12-16, Volume: 65, Issue:1

    Topics: Adult; Antitubercular Agents; Cycloserine; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Humans; Isoxazoles; Oxazolidinones; Pharmaceutical Preparations; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2020
New Topoisomerase Inhibitors: Evaluating the Potency of Gepotidacin and Zoliflodacin in Fluoroquinolone-Resistant Escherichia coli upon
    Antimicrobial agents and chemotherapy, 2021, 01-20, Volume: 65, Issue:2

    Topics: Acenaphthenes; Anti-Bacterial Agents; Barbiturates; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Fluoroquinolones; Heterocyclic Compounds, 3-Ring; Isoxazoles; Morpholines; Multidrug Resistance-Associated Proteins; Oxazolidinones; Spiro Compounds; Topoisomerase Inhibitors

2021
Investigation of clomazone-tolerance mechanism in a long-grain cultivar of rice.
    Pest management science, 2021, Volume: 77, Issue:5

    Topics: Chromosomes, Plant; Isoxazoles; Oryza; Oxazolidinones

2021
Effects of the technical ingredient clomazone and its two formulated products on aquatic macrophytes.
    Environmental pollution (Barking, Essex : 1987), 2021, May-15, Volume: 277

    Topics: Herbicides; Isoxazoles; Oxazolidinones; Water Pollutants, Chemical

2021
Neuropsychiatric toxicity and cycloserine concentrations during treatment for multidrug-resistant tuberculosis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 105

    Topics: Adult; Antibiotics, Antitubercular; Cycloserine; Depression; Female; HIV Infections; Humans; Incidence; Isoxazoles; Male; Middle Aged; Oxazolidinones; Peripheral Nervous System Diseases; Prospective Studies; Psychoses, Substance-Induced; Risk Factors; Tuberculosis, Multidrug-Resistant

2021
Clomazone improves the interactions between soil microbes and affects C and N cycling functions.
    The Science of the total environment, 2021, May-20, Volume: 770

    Topics: Isoxazoles; Oxazolidinones; Soil; Soil Microbiology

2021
Residues and dietary intake risk assessments of clomazone, fomesafen, haloxyfop-methyl and its metabolite haloxyfop in spring soybean field ecosystem.
    Food chemistry, 2021, Oct-30, Volume: 360

    Topics: Benzamides; Chromatography, High Pressure Liquid; Ecosystem; Glycine max; Herbicides; Humans; Isoxazoles; Oxazolidinones; Pesticide Residues; Pyridines; Risk Assessment; Seasons; Tandem Mass Spectrometry

2021
Influence of the quality of capsule shell on the non-invasive monitoring of medicines using Terizidone as an example.
    Journal of pharmaceutical and biomedical analysis, 2021, Sep-10, Volume: 204

    Topics: Capsules; Isoxazoles; Oxazolidinones

2021
Using a public database of Neisseria gonorrhoeae genomes to detect mutations associated with zoliflodacin resistance.
    The Journal of antimicrobial chemotherapy, 2021, 10-11, Volume: 76, Issue:11

    Topics: Anti-Bacterial Agents; Barbiturates; Drug Resistance, Bacterial; Gonorrhea; Humans; Isoxazoles; Microbial Sensitivity Tests; Morpholines; Mutation; Neisseria gonorrhoeae; Oxazolidinones; Spiro Compounds

2021
Negative cross-resistance to clomazone in imazethapyr-resistant Echinochloa crus-galli caused by increased metabolization.
    Pesticide biochemistry and physiology, 2021, Volume: 178

    Topics: Acetolactate Synthase; Echinochloa; Herbicide Resistance; Herbicides; Isoxazoles; Nicotinic Acids; Oxazolidinones

2021
Imaging of astrocytes in posttraumatic stress disorder: A PET study with the monoamine oxidase B radioligand [
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022, Volume: 54

    Topics: Astrocytes; Brain; Depressive Disorder, Major; Humans; Isoxazoles; Monoamine Oxidase; Oxazolidinones; Positron-Emission Tomography; Stress Disorders, Post-Traumatic

2022
Rapid and sensitive detection of clomazone in potato and pumpkin samples using a gold nanoparticle-based lateral-flow strip.
    Food chemistry, 2022, May-01, Volume: 375

    Topics: Cucurbita; Enzyme-Linked Immunosorbent Assay; Gold; Gold Colloid; Immunoassay; Isoxazoles; Limit of Detection; Metal Nanoparticles; Oxazolidinones; Solanum tuberosum

2022