Page last updated: 2024-08-25

oxazolidin-2-one and evacetrapib

oxazolidin-2-one has been researched along with evacetrapib in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's23 (95.83)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Einecke, D1
Fisher, EA; Hewing, B1
Duivenvoorden, R; Fayad, ZA1
Goldberg, AS; Hegele, RA1
Bochem, AE; Kuivenhoven, JA; Stroes, ES1
Ballantyne, CM; Catapano, AL; Norata, GD1
Akhlaghi, F; Mohammadpour, AH1
Escribano, A; Mantlo, NB1
Cai, J; Chen, C; Hu, Z; Li, C; Li, Y; Liu, L; Luo, H; Pei, F; Zeng, C; Zhang, W; Zhou, F; Zhou, L1
deGoma, EM; Rader, DJ1
Berthold, HK; Gouni-Berthold, I1
McCullough, PA; Shin, HJ1
Inazu, A; Mabuchi, H; Nohara, A1
Friedrich, S; Hall, SD; Ke, AB; Mantlo, N; Rotelli, M; Small, DS1
Barter, PJ; Kastelein, JJ; Nicholls, SJ; Rye, KA1
Boekholdt, SM; Hovingh, GK; Ray, KK1
Quintão, EC1
Barkas, F; Elisaf, M; Filippatos, TD; Klouras, E1
Crucet, M; Doycheva, P; Giral, H; Jukema, JW; Kratzer, A; Kühnast, S; Landmesser, U; Lüscher, TF; Mocharla, P; Osto, E; Princen, HM; Simic, B; Speer, T; Staels, B; Stivala, S; Tailleux, A; van der Hoorn, JW1
Avorn, J; Franklin, JM; Hey, SP; Kesselheim, AS1
Ding, Q; Fan, J; Liu, Z; Niimi, M; Wang, L; Wang, Z; Xu, J; Zhang, J1
Cao, Y; Hao, D; Yang, Z; Yuan, X; Zhang, L; Zhang, S1
Corsini, A; Macchi, C; Matsuzawa, Y; Ruscica, M; Sirtori, CR; Yamashita, S1
Bis, JC; Charoen, P; Chaturvedi, N; Drenos, F; Finan, C; Franceschini, N; Gaunt, TR; Giambartolomei, C; Gordillo-Marañón, M; Hingorani, AD; Hughes, AD; Hunt, NB; Kivimaki, M; Lawlor, DA; Mook-Kanamori, DO; O'Donnell, CJ; Papacosta, O; Price, JF; Schmidt, AF; Sofat, R; Wannamethee, G; Wong, A; Zwierzyna, M1

Reviews

16 review(s) available for oxazolidin-2-one and evacetrapib

ArticleYear
Rationale for cholesteryl ester transfer protein inhibition.
    Current opinion in lipidology, 2012, Volume: 23, Issue:4

    Topics: Amides; Animals; Benzodiazepines; Cholesterol Ester Transfer Proteins; Drug Discovery; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2012
Safety of CETP inhibition.
    Current opinion in lipidology, 2012, Volume: 23, Issue:6

    Topics: Amides; Animals; Benzodiazepines; Cholesterol Ester Transfer Proteins; Esters; Humans; Oxazolidinones; Quinolines; Safety; Sulfhydryl Compounds

2012
Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib.
    Drug design, development and therapy, 2012, Volume: 6

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Dyslipidemias; Esters; Humans; Lipoproteins, HDL; Oxazolidinones; Sulfhydryl Compounds

2012
The promise of cholesteryl ester transfer protein (CETP) inhibition in the treatment of cardiovascular disease.
    Current pharmaceutical design, 2013, Volume: 19, Issue:17

    Topics: Animals; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Humans; Oxazolidinones

2013
New therapeutic principles in dyslipidaemia: focus on LDL and Lp(a) lowering drugs.
    European heart journal, 2013, Volume: 34, Issue:24

    Topics: Azetidines; Benzimidazoles; Benzodiazepines; Carrier Proteins; Cholesterol, LDL; Dicarboxylic Acids; Dyslipidemias; Ezetimibe; Fatty Acids; Humans; Hypolipidemic Agents; Lipoprotein(a); Oligonucleotides; Oxazolidinones; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases

2013
Update on the discovery and development of cholesteryl ester transfer protein inhibitors for reducing residual cardiovascular risk.
    Journal of medicinal chemistry, 2014, Jan-09, Volume: 57, Issue:1

    Topics: Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Clinical Trials, Phase III as Topic; Drug Discovery; Humans; Oxazolidinones; Risk Factors; Structure-Activity Relationship

2014
Cholesteryl ester transfer protein inhibitors in the treatment of dyslipidemia: a systematic review and meta-analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Amides; Anticholesteremic Agents; Benzodiazepines; Blood Pressure; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Dyslipidemias; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxazolidinones; Quinolines; Randomized Controlled Trials as Topic; Sulfhydryl Compounds; Treatment Outcome; Triglycerides

2013
Future of cholesteryl ester transfer protein inhibitors.
    Annual review of medicine, 2014, Volume: 65

    Topics: Amides; Anticholesteremic Agents; Atherosclerosis; Benzodiazepines; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2014
Familial hypercholesterolemia: etiology, diagnosis and new treatment options.
    Current pharmaceutical design, 2014, Volume: 20, Issue:40

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; Benzimidazoles; Benzodiazepines; Humans; Hyperlipoproteinemia Type II; Oligonucleotides; Oxazolidinones

2014
Focus on lipids: high-density lipoprotein cholesterol and its associated lipoproteins in cardiac and renal disease.
    Nephron. Clinical practice, 2014, Volume: 127, Issue:1-4

    Topics: Amides; Apolipoprotein A-I; Benzodiazepines; Black or African American; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Esters; Heart Diseases; Humans; Hyperlipoproteinemias; Kidney Diseases; Liver; Niacin; Observational Studies as Topic; Oxazolidinones; Prospective Studies; Quinolines; Randomized Controlled Trials as Topic; Risk; Sulfhydryl Compounds; Triglycerides; White People

2014
Cholesteryl ester transfer protein (CETP) deficiency and CETP inhibitors.
    Molecules and cells, 2014, Volume: 37, Issue:11

    Topics: Animals; Atherosclerosis; Benzodiazepines; Cholesterol; Cholesterol Ester Transfer Proteins; Clinical Trials as Topic; Coronary Disease; Humans; Lipid Metabolism, Inborn Errors; Oxazolidinones

2014
The controversy over the use of cholesteryl ester transfer protein inhibitors: is there some light at the end of the tunnel?
    European journal of clinical investigation, 2016, Volume: 46, Issue:6

    Topics: Amides; Animals; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Benzodiazepines; Cholesterol Ester Transfer Proteins; Esters; Humans; Hypercholesterolemia; Mice; Oxazolidinones; Quinolines; Rabbits; Sulfhydryl Compounds

2016
Cholesteryl ester transfer protein inhibitors: challenges and perspectives.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:8

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Esters; Humans; Lipids; Lipoprotein(a); Lipoproteins, HDL; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2016
Success, Failure, and Transparency in Biomarker-Based Drug Development: A Case Study of Cholesteryl Ester Transfer Protein Inhibitors.
    Circulation. Cardiovascular quality and outcomes, 2017, Volume: 10, Issue:6

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Biomarkers, Pharmacological; Cholesterol Ester Transfer Proteins; Drug Approval; Drug Discovery; Dyslipidemias; Endpoint Determination; Esters; Humans; Lipids; Oxazolidinones; Predictive Value of Tests; Quinolines; Reproducibility of Results; Sulfhydryl Compounds; Time Factors; Treatment Outcome

2017
Cholesteryl ester transfer protein: An enigmatic pharmacology - Antagonists and agonists.
    Atherosclerosis, 2018, Volume: 278

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Esters; Humans; Lignans; Lipoproteins, HDL; Lipoproteins, VLDL; Oxazolidinones; Probucol; Quinolines; Sulfhydryl Compounds; Triglycerides

2018
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
    Nature communications, 2021, 09-24, Volume: 12, Issue:1

    Topics: Amides; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Coronary Disease; Esters; Humans; Mendelian Randomization Analysis; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2021

Other Studies

8 other study(ies) available for oxazolidin-2-one and evacetrapib

ArticleYear
[Secondary coronary heart disease prevention. Will CEPT inhibitors be the next breakthrough?].
    MMW Fortschritte der Medizin, 2011, Dec-08, Volume: 153, Issue:49-50

    Topics: Acute Coronary Syndrome; Amides; Benzodiazepines; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Delayed-Action Preparations; Drug Therapy, Combination; Drugs, Investigational; Esters; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Oxazolidinones; Randomized Controlled Trials as Topic; Sulfhydryl Compounds

2011
Future of cholesteryl ester transfer protein (CETP) inhibitors: a pharmacological perspective.
    Clinical pharmacokinetics, 2013, Volume: 52, Issue:8

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Coronary Artery Disease; Esters; Humans; Oxazolidinones; Quinolines; Sulfhydryl Compounds

2013
Assessment of the persistence of anacetrapib and evacetrapib concentrations using two pharmacokinetic modeling approaches.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:7

    Topics: Anticholesteremic Agents; Benzodiazepines; Cholesterol Ester Transfer Proteins; Half-Life; Humans; Models, Biological; Oxazolidinones; Time Factors

2015
Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP Inhibition as a Strategy to Reduce Cardiovascular Risk: The Pro Case.
    Circulation, 2015, Aug-04, Volume: 132, Issue:5

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Esters; Humans; Lipid Metabolism, Inborn Errors; Mice; Oxazolidinones; Quinolines; Rabbits; Risk Factors; Sulfhydryl Compounds; Treatment Outcome

2015
Is Cholesteryl Ester Transfer Protein Inhibition an Effective Strategy to Reduce Cardiovascular Risk? CETP as a Target to Lower CVD Risk: Suspension of Disbelief?
    Circulation, 2015, Aug-04, Volume: 132, Issue:5

    Topics: Amides; Animals; Anticholesteremic Agents; Benzodiazepines; Cardiovascular Diseases; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Esters; Humans; Lipid Metabolism, Inborn Errors; Mice; Oxazolidinones; Quinolines; Rabbits; Risk Factors; Sulfhydryl Compounds; Treatment Outcome

2015
Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.
    Atherosclerosis, 2017, Volume: 257

    Topics: Animals; Anticholesteremic Agents; Apolipoprotein E3; Aryldialkylphosphatase; Benzodiazepines; Biomarkers; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Humans; Mice, Transgenic; Oxazolidinones; Phenotype; Reactive Oxygen Species; Triglycerides; Up-Regulation; Vasodilation

2017
Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Animals; Anticholesteremic Agents; Benzodiazepines; Binding Sites; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cricetinae; Guinea Pigs; Lipoproteins, LDL; Male; Molecular Dynamics Simulation; Oxazolidinones; Phylogeny; Protein Structure, Tertiary; Rabbits; Triglycerides

2017
Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:10

    Topics: Anticholesteremic Agents; Benzodiazepines; Binding Sites; Cholesterol Ester Transfer Proteins; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Oxazolidinones; Protein Binding; Protein Structure, Secondary; Quinolines; Solvents; Thermodynamics

2018