Page last updated: 2024-08-21

oxazoles and trimethadione

oxazoles has been researched along with trimethadione in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	99 (97.06)	18.7374
1990's	3 (2.94)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Nuhn, P; Woitkowitz, P	1
King, WM; Kreisman, NR; Murphy, MF	1
Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH	1
Mayevsky, A	1
Grudzinska, E; Ilczuk, I; Lechowska-Postek, M; Rump, S	1
Feldman, GL; Lovrien, EW; Weaver, DD	1
Lightner, ES; Rosen, RC	1
Hecht, F	1
Buttar, HS; Dupuis, I; Midha, KK; Rowe, M	1
Brown, NA; Fabro, S; Shull, G	1
Anhut, H; Hertting, G; Steinhauer, HB	1
Rischbieth, RH	1
Goldman, AS; Yaffe, SJ	1
Isaac, L; McMillen, BA	1
Krolner, B	1
Hayakawa, T; Kamiya, N; Noda, A; Takayama, T	1
Chiu, P; Colasanti, BK; Craig, CR	1
Hayakawa, T; Nakajima, S; Noda, A; Suzuki, T; Toda, Y	2
Aoki, I; Hayakawa, T; Horiguchi, Y; Noda, A; Toda, Y	1
Ohtsubo, K	1
Etoh, H; Misawa, S; Tanaka, E	1
Kobayashi, S; Misawa, S; Tanaka, E; Yasuhara, H	1
Greco, GS; Nagai, MK; Wells, PG	1
Fukao, K; Ishikawa, A; Iwasaki, Y; Misawa, S; Tanaka, E; Yamamoto, Y	1
Nakamura, K; Tanaka, E	1
Ishikawa, A; Misawa, S; Okamura, T; Ono, A; Tanaka, E	2
Kuroiwa, Y; Misawa, S; Tanaka, E	2
Ishikawa, A; Kuroiwa, Y; Misawa, S; Tanaka, E	1
Vorhees, CV	2
Misawa, S; Tanaka, E	2
Fukao, K; Ishikawa, A; Iwasaki, Y; Misawa, S; Tanaka, E; Tsuji, K	1
Hayakawa, T; Hiramatsu, E; Horiguchi, Y; Kameya, S; Noda, A; Ogawa, Y; Shibata, T; Watanabe, T	1
Nakanishi, Y; Noda, A; Yamamoto, K	1
Ishikawa, A; Kobayashi, S; Misawa, S; Okamura, T; Ono, A; Tanaka, E; Yasuhara, H	1
Ishikawa, A; Misawa, S; Okamura, T; Ono, A; Takada, A; Tanaka, E	1
Kurata, N; Kuroiwa, Y; Misawa, S; Tanaka, E	1
Khera, KS	1
Kuroiwa, Y; Tanaka, E; Yoshida, T	1
Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H	1
Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H	1
De George, FV; Ehlers, KH; Engle, MA; German, J; Kowal, A; Passarge, E	1
Eldredge, NT; Jiller, JJ; van Robertson, WB	1
Frey, HH; Schulz, R	2
Brink, JJ; Freeman, EA	1
Millichap, JG	1
Hooshmand, H; Suter, CG	1
Glasky, AJ; Simon, LN	1
Rifkind, AB	1
Nichols, MM	1
Andrews, PR	1
McDonald, CG; Roll, BD	1
Booker, HE; Chun, RW; Sanguino, M	2
Aymat, F; Millichap, JG	1
Gilbert, GJ	1
Fromm, GH; Killian, JM; Sanchez, F	1
Ehlers, KH; German, J; Kowal, A	1
Nahorski, SR	1
Frey, HH; Kretschmer, BH	1
St Laurent, J	1
Dua, PR; Kohli, RP; Rastogi, SK; Singh, N; Sinha, JN	1
Amores, CY; Fromm, GH; Thies, W; Ulicny, TL	1
Booker, HE; Darcey, B	1
Southgate, PJ	1
Caldeira, JA; Ramos, AO; Ramos, L	1
Carrillo, L; de Bonnevaux, SC	1
Bennett, DA; Brugger, S; Dutta, P; Fielding, S; Geyer, H; Lal, H	1
Hamano, H; Hayakawa, T; Horiguchi, Y; Murase, T; Noda, A; Shibata, T; Takayama, T	1
King, WM; Kreisman, NR	1
Alderdice, MT; McMillan, JE	1
Friis, ML	1
Angel, A; Clarke, KA	1
Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H; Yoshida, T	1
Kuroiwa, Y; Misawa, S; Nakamura, T; Tanaka, E; Yoshida, T	1
Frankena, H; Zweens, J	1
Kinoshita, H; Kuroiwa, Y; Tanaka, E; Yoshida, T	7
Hagino, S; Kuroiwa, Y; Tanaka, E; Yoshida, T	1
Gajewski, D; Grudzińska, E	1
Kinoshita, H; Kuroiwa, Y; Takabatake, E; Tanaka, E; Yamamoto, T	1
BERTCHER, EL; TAYLOR, JD	1
CURLETTO, R; GASPERONI, G	1
LAWRENCE, DE	1
BUTLER, TC; MAHAFFEE, C; MAHAFFEE, D	1
BERGSTRAND, A; BERGSTRAND, CG; ENGSTROM, N; HERRLIN, KM	1
BILLE, S; BRANDT, S	1
BOKS, LL; LIVINGSTON, S	1
BLACK, RW; FORSEY, RR	1
BUTTER, AJ	1
NABARRO, JD; ROSENHEIM, ML	1
TEGELAERS, WH; TIDDENS, H	1

Reviews

2 review(s) available for oxazoles and trimethadione

Article	Year
[Diagnosis of pancreatic diseases: Biochemical tests]. Nihon rinsho. Japanese journal of clinical medicine, 1973, Volume: 31, Issue:3 Topics: Anticonvulsants; Cholecystokinin; Chronic Disease; Humans; Oxazoles; Pancreas; Pancreatic Cyst; Pancreatic Diseases; Pancreatic Juice; Pancreatic Neoplasms; Pancreatitis; Secretin; Trimethadione	1973
Treatment and prognosis of petit mal epilepsy. Pediatric clinics of North America, 1967, Volume: 14, Issue:4 Topics: Acetazolamide; Anticonvulsants; Child; Child, Preschool; Drug Synergism; Epilepsy, Absence; Ethosuximide; Humans; Oxazoles; Prognosis; Pyrrolidinones; Quinacrine; Succinimides; Trimethadione	1967

Trials

2 trial(s) available for oxazoles and trimethadione

Article	Year
Comparison of the therapeutic effects of trimethadione and phensuximide in acute organophosphate intoxications. Therapia Hungarica (English edition), 1978, Volume: 26, Issue:3 Topics: Acute Disease; Animals; Clinical Trials as Topic; Female; Insecticides; Male; Organophosphorus Compounds; Oxazoles; Rabbits; Succinimides; Trimethadione	1978
Observations on the discrepancy between the clinical and the laboratory effects of anti-petit mal drugs. Transactions of the American Neurological Association, 1967, Volume: 92 Topics: Action Potentials; Anticonvulsants; Chloralose; Clinical Trials as Topic; Diazepam; Epilepsy, Absence; Humans; Oxazoles; Pentylenetetrazole; Trigeminal Nerve; Trimethadione	1967

Other Studies

98 other study(ies) available for oxazoles and trimethadione

Article	Year
[Alkali-catalyzed hydrolysis of trimethadione]. Die Pharmazie, 1977, Volume: 32, Issue:11 Topics: Alkalies; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Oxazoles; Temperature; Trimethadione	1977
Effects of the anticonvulsant, trimethadione, on bursting pacemaker activity and recruitment of inhibition in the abdominal ganglion of Aplysia californica. Comparative biochemistry and physiology. C: Comparative pharmacology, 1978, Volume: 60, Issue:2 Topics: Animals; Aplysia; Dose-Response Relationship, Drug; Ganglia; Membrane Potentials; Neurons; Oxazoles; Trimethadione	1978
The fetal trimethadione syndrome. The Journal of pediatrics, 1975, Volume: 87, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental Disabilities; Ear, External; Epilepsy, Absence; Eye Abnormalities; Eyebrows; Female; Fetal Diseases; Fetus; Growth Disorders; Hand Deformities, Congenital; Hearing Disorders; Hernia, Inguinal; Humans; Hypospadias; Infant; Male; Microcephaly; Oxazoles; Palate; Phenobarbital; Pregnancy; Pregnancy Complications; Speech Disorders; Syndrome; Teratogens; Tooth Abnormalities; Trimethadione	1975
The effect of trimethadione on brain energy metabolism and EEG activity of the conscious rat exposed to HPO. Journal of neuroscience research, 1975, Volume: 1, Issue:2 Topics: Animals; Brain; Electroencephalography; Energy Metabolism; Hyperbaric Oxygenation; Male; NAD; Oxazoles; Rats; Seizures; Trimethadione	1975
The fetal trimethadione syndrome: report of an additional family and further delineation of this syndrome. American journal of diseases of children (1960), 1977, Volume: 131, Issue:12 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Infant, Newborn; Male; Oxazoles; Pregnancy; Pregnancy Complications; Trimethadione	1977
Phenotypic malformations in association with maternal trimethadione therapy. The Journal of pediatrics, 1978, Volume: 92, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Fetus; Growth Disorders; Humans; Intellectual Disability; Male; Maternal-Fetal Exchange; Oxazoles; Phenotype; Pregnancy; Trimethadione	1978
Fetal trimethadione toxicity: an historical footnote. American journal of diseases of children (1960), 1979, Volume: 133, Issue:5 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Pregnancy; Trimethadione	1979
Metabolism and disposition of trimethadione in pregnant rats. Epilepsia, 1979, Volume: 20, Issue:4 Topics: Abnormalities, Drug-Induced; Animals; Dimethadione; Drug Evaluation, Preclinical; Female; Fetus; Oxazoles; Pregnancy; Rats; Teratogens; Trimethadione	1979
Assessment of the teratogenic potential of trimethadione in the CD-1 mouse. Toxicology and applied pharmacology, 1979, Volume: 51, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Gestational Age; Growth; Lethal Dose 50; Mice; Oxazoles; Pregnancy; Teratogens; Trimethadione	1979
The synthesis of prostaglandins and thromboxane in the mouse brain in vivo. Influence of drug induced convulsions, hypoxia and the anticonvulsants trimethadione and diazepam. Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 310, Issue:1 Topics: Animals; Brain; Diazepam; In Vitro Techniques; Male; Mice; Oxazoles; Oxygen; Pentylenetetrazole; Picrotoxin; Prostaglandins; Seizures; Thromboxanes; Time Factors; Trimethadione	1979
Troxidone (trimethadione) embryopathy: case report with reveiw of the literature. Clinical and experimental neurology, 1979, Volume: 16 Topics: Abnormalities, Drug-Induced; Aorta; Child; Ductus Arteriosus, Patent; Ear, External; Female; Heart Defects, Congenital; Humans; Oxazoles; Pregnancy; Subclavian Artery; Teratogens; Trimethadione	1979
Fetal trimethadione syndrome. Teratology, 1978, Volume: 17, Issue:1 Topics: Abnormalities, Drug-Induced; Ear, External; Epilepsy; Eyebrows; Female; Humans; Male; Oxazoles; Palate; Pregnancy; Pregnancy Complications; Syndrome; Tooth Abnormalities; Trimethadione	1978
Effects of pentylenetetrazol and trimethadione on feline brain monoamine metabolism. Biochemical pharmacology, 1978, Volume: 27, Issue:14 Topics: Animals; Biogenic Amines; Body Temperature; Brain; Cats; Half-Life; Oxazoles; Pentylenetetrazole; Time Factors; Trimethadione; Tryptophan	1978
[Trimethadione nephropathy]. Ugeskrift for laeger, 1977, Jan-31, Volume: 139, Issue:5 Topics: Adult; Epilepsy; Humans; Male; Nephrotic Syndrome; Oxazoles; Trimethadione	1977
Pancreatolithiasis and pancreatic carcinoma. Evaluation of pancreatic excretion test with 5,5-dimethyl-2,4-oxazolidinedione. Archives of internal medicine, 1977, Volume: 137, Issue:6 Topics: Calculi; Cholecystokinin; Dimethadione; Duodenum; Humans; Oxazoles; Pancreatic Diseases; Pancreatic Neoplasms; Secretin; Trimethadione	1977
Effects of diphenylhydantoin and trimethadione on seizure activity during cobalt experimental epilepsy in the rat. Neuropharmacology, 1976, Volume: 15, Issue:8 Topics: Animals; Cobalt; Female; Oxazoles; Phenytoin; Rats; Seizures; Time Factors; Trimethadione	1976
Pancreatic excretion of 5, 5-dimethyl-2, 4-oxazolidinedione in normal subjects. The American journal of digestive diseases, 1975, Volume: 20, Issue:11 Topics: Adult; Aged; Bicarbonates; Bilirubin; Cholecystokinin; Dimethadione; Duodenum; Female; Humans; Intestinal Secretions; Male; Middle Aged; Oxazoles; Pancreas; Secretin; Trimethadione	1975
Pancreatic excretion of 5,5-dimethyl-2,4-oxazolidinedione in patients with chronic pancreatitis. The American journal of digestive diseases, 1975, Volume: 20, Issue:11 Topics: Adult; Cholecystokinin; Chronic Disease; Dimethadione; Duodenum; Female; Humans; Intestinal Secretions; Male; Middle Aged; Oxazoles; Pancreas; Pancreatitis; Secretin; Trimethadione	1975
[Therapeutic drug monitoring of trimethadione]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48 Suppl Topics: Abnormalities, Drug-Induced; Adult; Aged; Biological Availability; Chromatography, Gas; Female; Humans; Male; Maternal-Fetal Exchange; Middle Aged; Oxazoles; Pregnancy; Trimethadione	1990
The effects of selective cytochrome P-450 inducing agents on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in rats. Research communications in chemical pathology and pharmacology, 1990, Volume: 68, Issue:3 Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Trimethadione	1990
Strain differences of antipyrine, trimethadione, and debrisoquine metabolism in female rats. Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:2 Topics: Analysis of Variance; Animals; Antipyrine; Debrisoquin; Female; Isoquinolines; Oxazoles; Rats; Rats, Inbred Strains; Species Specificity; Trimethadione	1990
Inhibition of trimethadione and dimethadione teratogenicity by the cyclooxygenase inhibitor acetylsalicylic acid: a unifying hypothesis for the teratologic effects of hydantoin anticonvulsants and structurally related compounds. Toxicology and applied pharmacology, 1989, Mar-01, Volume: 97, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cleft Palate; Dealkylation; Dimethadione; Dose-Response Relationship, Drug; Female; Mice; Oxazoles; Phenytoin; Pregnancy; Trimethadione	1989
The metabolism and excretion of trimethadione in patients with percutaneous transhepatic biliary drainage and renal dysfunction. Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:3 Topics: Adult; Aged; Bile; Biliary Tract Diseases; Dimethadione; Female; Half-Life; Humans; Kidney Diseases; Male; Middle Aged; Oxazoles; Trimethadione	1989
Comparison of trimethadione and antipyrine as indicators of oxidative drug metabolizing capacity in man. European journal of clinical pharmacology, 1989, Volume: 36, Issue:6 Topics: Adult; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Humans; Male; Oxazoles; Trimethadione	1989
Trimethadione metabolism in patients with normal liver and in patients with chronic liver disease. Journal of pharmacobio-dynamics, 1987, Volume: 10, Issue:9 Topics: Carcinoma, Hepatocellular; Chronic Disease; Dimethadione; Female; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Oxazoles; Trimethadione	1987
Comparative effects of famotidine and cimetidine on trimethadione metabolism in the rat. Biochemical pharmacology, 1986, Mar-01, Volume: 35, Issue:5 Topics: Animals; Cimetidine; Famotidine; Histamine H2 Antagonists; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazoles; Rats; Thiazoles; Trimethadione	1986
Sex-related differences in hepatic drug-oxidizing capacity of streptozotocin-induced diabetic rats. Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:6 Topics: Animals; Antipyrine; Diabetes Mellitus, Experimental; Dimethadione; Female; Insulin; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sex Factors; Trimethadione	1988
Fetal anticonvulsant exposure: effects on behavioral and physical development. Annals of the New York Academy of Sciences, 1986, Volume: 477 Topics: Animals; Anticonvulsants; Female; Humans; Learning; Memory; Motor Activity; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reflex, Startle; Trimethadione	1986
Simultaneous determination of serum trimethadione and its metabolite by gas chromatography. Journal of chromatography, 1987, Jan-23, Volume: 413 Topics: Animals; Biotransformation; Chromatography, Gas; Dimethadione; Humans; Oxazoles; Rats; Species Specificity; Trimethadione	1987
Age-related changes in trimethadione oxidizing capacity. British journal of clinical pharmacology, 1987, Volume: 23, Issue:3 Topics: Adult; Aged; Aging; Alanine Transaminase; Aspartate Aminotransferases; Dimethadione; Half-Life; Humans; Kinetics; Male; Middle Aged; Oxazoles; Oxidation-Reduction; Serum Albumin; Trimethadione	1987
[Measurement of microsomal function in hepatectomized rat]. Nihon Geka Gakkai zasshi, 1987, Volume: 88, Issue:3 Topics: Animals; Carbon Tetrachloride Poisoning; Dimethadione; Hepatectomy; Liver; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Inbred Strains; Trimethadione	1987
Dissolution of pancreatic stones by oral trimethadione in a dog experimental model. Gastroenterology, 1987, Volume: 93, Issue:5 Topics: Administration, Oral; Animals; Calculi; Dogs; Oxazoles; Pancreatic Diseases; Time Factors; Trimethadione	1987
Comparative pharmacokinetic study of trimethadione and dimethadione for lysis of pancreatic stones. Gastroenterologia Japonica, 1986, Volume: 21, Issue:2 Topics: Administration, Oral; Animals; Dimethadione; Dogs; Metabolic Clearance Rate; Oxazoles; Pancreatic Diseases; Trimethadione	1986
Trimethadione tolerance test for evaluation of functional reserve of the liver in patients with liver cirrhosis and esophageal varices. Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:3 Topics: Adult; Dimethadione; Esophageal and Gastric Varices; Female; Humans; Kinetics; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Oxazoles; Trimethadione	1986
Hepatic trimethadione-oxidizing capacity remains normal in patients with extrahepatic cholelithiasis. Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:5 Topics: Bilirubin; Cholelithiasis; Dimethadione; Humans; Liver; Middle Aged; Oxazoles; Trimethadione	1986
Influence of short-term water deprivation on kinetics of trimethadione and its metabolite in rats. Japanese journal of pharmacology, 1986, Volume: 42, Issue:2 Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Dimethadione; Food Deprivation; Kinetics; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Inbred Strains; Trimethadione; Water Deprivation	1986
Phenytoin and trimethadione: pharmacokinetics, embryotoxicity, and maternal toxicity. Progress in clinical and biological research, 1985, Volume: 163C Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Half-Life; Humans; Infant, Newborn; Kinetics; Oxazoles; Phenytoin; Pregnancy; Pregnancy, Animal; Risk; Trimethadione	1985
Effects of cimetidine and ranitidine on trimethadione metabolism in the rat. Research communications in chemical pathology and pharmacology, 1985, Volume: 47, Issue:3 Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cimetidine; Cytochrome P-450 Enzyme System; Half-Life; Kinetics; Liver; Male; Oxazoles; Ranitidine; Rats; Rats, Inbred Strains; Trimethadione	1985
Dose-independent pharmacokinetics of trimethadione and its metabolite in rats. Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:3 Topics: Animals; Chromatography, Gas; Dimethadione; Kinetics; Liver; Male; Oxazoles; Rats; Rats, Inbred Strains; Time Factors; Trimethadione	1985
The effects of short-term administration of ibuprofen on trimethadione metabolism and antipyrine metabolite formation in the rat. Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2 Topics: Animals; Antipyrine; Ibuprofen; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione	1985
Effects of cimetidine and diethylaminoethyl 2,2-diphenylvalerate HCL (SKF 525-A) on trimethadione metabolism in the rat. Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9 Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Dimethadione; Kinetics; Liver; Male; Oxazoles; Proadifen; Rats; Rats, Inbred Strains; Trimethadione	1985
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator. Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9 Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione	1985
Possible teratogenicity of trimethadione and paramethadione. Lancet (London, England), 1970, Aug-01, Volume: 2, Issue:7666 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Epilepsy; Female; Heart Defects, Congenital; Humans; New York City; Oxazoles; Pregnancy; Pregnancy Complications; Trimethadione	1970
The interaction of lupus-inducing drugs with deoxyribonucleic acid. Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2 Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity	1974
Time course of the demethylation of trimethadione to dimethadione. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4 Topics: Animals; Anticonvulsants; Biotransformation; Dealkylation; Dogs; Mice; Oxazoles; Time Factors; Trimethadione	1970
Effects of 5-phenyloxazolidinedione on sodium-potassium-magnesium-activated adenosine triphosphatase activity in mouse brain. Journal of neurochemistry, 1972, Volume: 19, Issue:7 Topics: Adenosine Triphosphatases; Animals; Anticonvulsants; Brain; Carbon Isotopes; Chemical Phenomena; Chemistry; Enzyme Activation; Female; Imines; Ketones; Lethal Dose 50; Magnesium; Mice; Ouabain; Oxazoles; Potassium; Seizures; Sodium; Trimethadione	1972
Drug treatment of convulsive disorders. The New England journal of medicine, 1972, Mar-02, Volume: 286, Issue:9 Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione	1972
Classification and treatment of seizure disorders in children. Virginia medical monthly, 1970, Volume: 97, Issue:2 Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Infant, Newborn; Male; Nitrazepam; Oxazoles; Phenytoin; Seizures; Succinimides; Trimethadione	1970
Magnesium pemoline: enhancement of brain RNA polymerases. Science (New York, N.Y.), 1966, Feb-11, Volume: 151, Issue:3711 Topics: Animals; Anticonvulsants; Brain; Imipramine; In Vitro Techniques; Magnesium; Methamphetamine; Methylphenidate; Nucleotidyltransferases; Oxazoles; Pargyline; Pemoline; Piperidines; Rats; RNA; Trimethadione	1966
Teratogenic effects of trimethadione and dimethadione in the chich embryo. Toxicology and applied pharmacology, 1974, Volume: 30, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Dimethylamines; Oxazoles; Spectrophotometry, Ultraviolet; Teratogens; Trimethadione	1974
Fetal anomalies following maternal trimethadione ingestion. The Journal of pediatrics, 1973, Volume: 82, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Female; Heart Defects, Congenital; Hernia, Umbilical; Humans; Infant, Newborn; Oxazoles; Pregnancy; Spinal Dysraphism; Trimethadione	1973
Binding of CNS active drugs to the peptide bond: a model system and mode of action hypothesis. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:11 Topics: Anilides; Anticonvulsants; Bemegride; Binding Sites; Chemical Phenomena; Chemistry; Magnetic Resonance Spectroscopy; Oxazoles; Pentobarbital; Peptides; Protein Binding; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Trimethadione	1972
Letter: Analysis of trimethadione by NMR. Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:10 Topics: Anticonvulsants; Magnetic Resonance Spectroscopy; Oxazoles; Solvents; Trimethadione	1973
Myasthenic syndrome associated with trimethadione. Neurology, 1968, Volume: 18, Issue:3 Topics: Anticonvulsants; Autoantibodies; Child; Epilepsy, Absence; Female; Humans; Myasthenia Gravis; Oxazoles; Trimethadione	1968
Myasthenia gravis syndrome associated with trimethadione. JAMA, 1970, Jun-29, Volume: 212, Issue:13 Topics: Anticonvulsants; Autoimmune Diseases; Child; Drug Hypersensitivity; Epilepsy, Absence; Female; Humans; Mephobarbital; Myasthenia Gravis; Neostigmine; Oxazoles; Primidone; Trimethadione	1970
Myasthenia gravis and epilepsy. The Journal of the Florida Medical Association, 1970, Volume: 57, Issue:5 Topics: Adult; Anticonvulsants; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Myasthenia Gravis; Oxazoles; Trimethadione	1970
Trimethadione and human teratogenesis. Teratology, 1970, Volume: 3, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Spontaneous; Adult; Epilepsy, Absence; Female; Humans; Infant; Infant Mortality; Infant, Newborn; Oxazoles; Pedigree; Pregnancy; Trimethadione	1970
Biochemical effects of the anticonvulsants trimethadione, ethosuximide and chlordiazepoxide in rat brain. Journal of neurochemistry, 1972, Volume: 19, Issue:8 Topics: Adenine Nucleotides; Amino Acids; Animals; Anticonvulsants; Blood Glucose; Brain; Chlordiazepoxide; Ethosuximide; Glucose; Glucosephosphates; Glycogen; Hexosephosphates; Oxazoles; Phosphocreatine; Rats; Tricarboxylic Acids; Trimethadione	1972
Anticonvulsant effect of trimethadione in mice during continued treatment via the drinking water. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1 Topics: Animals; Anticonvulsants; Female; Male; Mice; Osmolar Concentration; Oxazoles; Pentylenetetrazole; Seizures; Trimethadione; Water	1971
Effect of trimethadione on the self-stimulation phenomenon. Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:9 Topics: Animals; Anticonvulsants; Electric Stimulation; Hypothalamus; Male; Oxazoles; Rats; Self Stimulation; Trimethadione	1971
An experimental investigation on the antiarrhythmic activity of antiepileptic agents. Japanese journal of pharmacology, 1971, Volume: 21, Issue:6 Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Electrocardiography; Epinephrine; Female; Ligation; Male; Oxazoles; Phenytoin; Quinidine; Trimethadione	1971
Depression of cortical inhibitory pathways by trimethadione and by imipramine. Neurology, 1970, Volume: 20, Issue:4 Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Electric Stimulation; Functional Laterality; Imipramine; Maxillary Nerve; Motor Cortex; Oxazoles; Trigeminal Nerve; Trimethadione	1970
Time course of the demethylation of trimethadione. Acta pharmacologica et toxicologica, 1970, Volume: 28, Issue:6 Topics: Animals; Anticoagulants; Chromatography, Gas; Dogs; Female; Male; Methods; Mice; Oxazoles; Spectrophotometry; Trimethadione	1970
Simultaneous determination of trimethadione and its metabolite, dimethadione, by gas-liquid chromatography. Clinical chemistry, 1971, Volume: 17, Issue:7 Topics: Anticonvulsants; Chromatography, Gas; Humans; Methods; Oxazoles; Trimethadione	1971
A comparison of the anticonvulsant properties of 2-diethylaminopento-4-ynoyl-2',6'-xylidide (WY 21745) with lignocaine, phenytoin, phenobarbitone and trimethadione. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:2 Topics: Anesthetics, Local; Animals; Anticonvulsants; Drug Antagonism; Electroshock; Lethal Dose 50; Lidocaine; Mice; Oxazoles; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione	1971
[Eye hypotension due to anticonvulsants in rabbits]. Arquivos brasileiros de oftalmologia, 1967, Volume: 30, Issue:5 Topics: Animals; Anticonvulsants; Female; Intraocular Pressure; Male; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Trimethadione	1967
Autonomic response to pentamethylenetetrazol following trimetadione and benzodiazepines administration. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1 Topics: Animals; Anticonvulsants; Autonomic Nervous System; Blood Glucose; Blood Pressure; Chlordiazepoxide; Curare; Diazepam; Drug Antagonism; Female; Hyperglycemia; Male; Oxazoles; Pentylenetetrazole; Pupil; Rabbits; Trimethadione	1968
Comparison of the actions of trimethadione and chlordiazepoxide in animal models of anxiety and benzodiazepine receptor binding. Neuropharmacology, 1982, Volume: 21, Issue:11 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Discrimination Learning; Disease Models, Animal; Humans; Male; Oxazoles; Pentylenetetrazole; Rats; Receptors, Cell Surface; Receptors, GABA-A; Trimethadione	1982
Trimethadione (troxidone) dissolves pancreatic stones. Lancet (London, England), 1984, Aug-11, Volume: 2, Issue:8398 Topics: Adult; Aged; Animals; Calculi; Dogs; Humans; Male; Middle Aged; Oxazoles; Pancreatic Diseases; Trimethadione	1984
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Developmental Disabilities; Dose-Response Relationship, Drug; Female; Fetus; Gestational Age; Humans; Locomotion; Oxazoles; Phenobarbital; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains; Reflex, Startle; Swimming; Syndrome; Time Factors; Trimethadione	1983
Trimethadione effects on cholinergic responses in Aplysia neurons. Brain research, 1981, Mar-23, Volume: 209, Issue:1 Topics: Acetylcholine; Animals; Aplysia; Chlorides; Evoked Potentials; Ganglia; Neurons; Oxazoles; Potassium; Receptors, Cholinergic; Sodium; Synaptic Transmission; Trimethadione	1981
Comparison of the effects of trimethadione and its primary metabolite dimethadione on neuromuscular function and the effects of altered pH on the actions of dimethadione. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3 Topics: Animals; Dimethadione; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Oxazoles; Rana pipiens; Synaptic Transmission; Time Factors; Trimethadione	1982
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled? Acta neurologica Scandinavica. Supplementum, 1983, Volume: 94 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Risk; Trimethadione; Valproic Acid	1983
The effects of trimethadione on pentetrazol-induced discharges of primary muscle spindle afferents from the hind limb of the rat. British journal of pharmacology, 1981, Volume: 72, Issue:1 Topics: Afferent Pathways; Animals; Female; Hindlimb; In Vitro Techniques; Muscle Spindles; Oxazoles; Pentylenetetrazole; Rats; Spinal Nerve Roots; Trimethadione	1981
A method for estimation of hepatic drug-metabolizing capacity: determination of concentration of trimethadione and its metabolite in human serum. Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:5 Topics: Adult; Animals; Antipyrine; Dimethadione; Half-Life; Humans; Kinetics; Liver; Male; Middle Aged; Oxazoles; Rats; Trimethadione	1984
Effects of allyl alcohol and bromobenzene on trimethadione metabolism in the rat. Research communications in chemical pathology and pharmacology, 1984, Volume: 45, Issue:1 Topics: 1-Propanol; Animals; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dimethadione; Kinetics; Liver; Male; Microsomes, Liver; Oxazoles; Oxidation-Reduction; Propanols; Proteins; Rats; Rats, Inbred Strains; Trimethadione	1984
Simultaneous determination of dimethadione and trimethadione by infrared-spectrometry: application for mean intracellular pH measurement. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1984, Volume: 22, Issue:10 Topics: Dimethadione; Humans; Hydrogen-Ion Concentration; Magnesium Sulfate; Oxazoles; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfates; Trimethadione	1984
Relationship between trimethadione metabolism and hepatic drug-oxidizing enzyme activities in different animal species. Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:7 Topics: Animals; Antipyrine; Cricetinae; Cytochrome P-450 Enzyme System; Dimethadione; Kinetics; Liver; Male; Mice; Oxazoles; Rabbits; Rats; Species Specificity; Trimethadione	1983
Simultaneous determination of trimethadione and its metabolite in rat and human serum by high-performance liquid chromatography. Journal of chromatography, 1984, Jun-08, Volume: 308 Topics: Administration, Oral; Adult; Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Dimethadione; Half-Life; Humans; Kinetics; Male; Middle Aged; Oxazoles; Rats; Rats, Inbred Strains; Species Specificity; Trimethadione	1984
Determination of trimethadione and its metabolite by gas chromatography with flame-thermionic detection and its application to pharmacokinetic studies of the drug in carbon tetrachloride-treated rats. Journal of chromatography, 1983, Feb-11, Volume: 272, Issue:2 Topics: Animals; Carbon Tetrachloride; Chromatography, Gas; Dimethadione; Half-Life; Kinetics; Male; Oxazoles; Rats; Rats, Inbred Strains; Trimethadione	1983
[Effects of trimethadione on the therapeutic efficiency of atropine and obidoxime in mice poisoned with various phosphoorganic compounds]. Medycyna pracy, 1981, Volume: 32, Issue:5 Topics: Animals; Atropine; Blood-Brain Barrier; Drug Synergism; Female; Lethal Dose 50; Mice; Mice, Inbred BALB C; Obidoxime Chloride; Organophosphate Poisoning; Oxazoles; Oximes; Trimethadione	1981
Studies on the trimethadione metabolism as a tool for the assessment of drug-metabolizing capacity using plasma and urine of rats pretreated with phenobarbital and 3-methylcholanthrene. Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:3 Topics: Animals; Biotransformation; Creatinine; Glucaric Acid; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Oxazoles; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Trimethadione	1982
Trimethadione as a model drug for the evaluation of hepatic drug-metabolizing capacity in normal and alpha-naphthylisothiocyanate-intoxicated rats. Pharmacology, 1982, Volume: 25, Issue:4 Topics: 1-Naphthylisothiocyanate; Animals; Dose-Response Relationship, Drug; Kinetics; Liver; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Inbred Strains; Thiocyanates; Trimethadione	1982
Trimethadione as a model drug for the evaluation of hepatic drug-metabolizing capacity in normal and D-galactosamine intoxicated rats. Japanese journal of pharmacology, 1982, Volume: 32, Issue:6 Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Dimethadione; Galactosamine; Kinetics; Liver; Male; Oxazoles; Rats; Rats, Inbred Strains; Trimethadione	1982
Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced liver injury. Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:8 Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dimethadione; Galactosamine; Injections, Intravenous; Kinetics; Male; Oxazoles; Rats; Time Factors; Trimethadione	1981
Saliva levels of trimethadione and its metabolite as an index of drug metabolizing activity in rats. Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:12 Topics: Animals; Biotransformation; Hydrogen-Ion Concentration; Male; Oxazoles; Rats; Rats, Inbred Strains; Saliva; Time Factors; Trimethadione	1981
Determination of plasma trimethadione and its metabolite carbon tetrachloride-intoxicated rat liver: a useful tool for estimation of hepatic drug metabolizing capacity. Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:12 Topics: Animals; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Dimethadione; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazoles; Oxidoreductases; Rats; Rats, Inbred Strains; Time Factors; Trimethadione	1981
The determination and distribution of trimethadione (tridione) in animal tissues. The Journal of pharmacology and experimental therapeutics, 1952, Volume: 106, Issue:3 Topics: Animals; Humans; Oxazoles; Trimethadione	1952
[Secondary hemotoxic effect of tridione]. Giornale di clinica medica, 1952, Volume: 33, Issue:8 Topics: Hematopoietic System; Oxazoles; Trimethadione	1952
Near fatal hemolytic anemia during anti-epileptiform convulsion therapy with tridione. Journal of the American Veterinary Medical Association, 1952, Volume: 121, Issue:907 Topics: Anemia, Hemolytic; Animals; Dog Diseases; Dogs; Epilepsy; Oxazoles; Seizures; Trimethadione	1952
Metabolic demethylation of 3, 5, 5-trimethyl-2, 4-oxazolidinedione (trimethadione, tridione). Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 81, Issue:2 Topics: Anticonvulsants; Oxazoles; Trimethadione	1952
Renal histology during treatment with oxazolidine-diones (trimethadione, ethadione, and paramethadione). Pediatrics, 1962, Volume: 30 Topics: Anticonvulsants; Epilepsy; Humans; Kidney; Kidney Function Tests; Kidney Glomerulus; Nephrotic Syndrome; Oxazoles; Trimethadione	1962
[Treatment of epileptic lapses of consciousness in children; dimedione as compared with tridione, paradione and milontin in clinical use]. Ugeskrift for laeger, 1955, Mar-24, Volume: 117, Issue:12 Topics: Anticonvulsants; Consciousness; Epilepsy; Oxazoles; Succinimides; Trimethadione	1955
Use of the dione drugs (propazone, tridione, paradione, dimedione and malidone) in the treatment of epilepsy of children. The New England journal of medicine, 1955, Jul-28, Volume: 253, Issue:4 Topics: Anticonvulsants; Child; Epilepsy; Humans; Infant; Oxazoles; Trimethadione	1955
Tridione and paradione sensitivity. Canadian Medical Association journal, 1951, Volume: 64, Issue:2 Topics: Oxazoles; Trimethadione	1951
Tridione compared with malidone in the treatment of petit mal. Journal of neurology, neurosurgery, and psychiatry, 1952, Volume: 15, Issue:1 Topics: Anticonvulsants; Epilepsy; Epilepsy, Absence; Humans; Oxazoles; Trimethadione	1952
Nephrotic syndrome complicating tridione (troxidone) therapy. Lancet (London, England), 1952, May-31, Volume: 1, Issue:6718 Topics: Humans; Nephrosis; Nephrotic Syndrome; Oxazoles; Trimethadione	1952
[Tridione and nephrosis]. Maandschrift voor kindergeneeskunde, 1952, Volume: 20, Issue:1 Topics: Epilepsy; Nephrosis; Oxazoles; Trimethadione	1952