oxazoles has been researched along with pyrazines in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fotsch, C; St Jean, DJ | 1 |
| Gröger, D; Johne, S; Syring, U | 1 |
| Menon, MK; Vivonia, CA | 1 |
| Cheney, DL; McGill, W; Murray, TF | 1 |
| Bencsik, JR; Josey, JA; Kercher, T; O'Sullivan, M | 1 |
| Heinzl, S | 1 |
| Alcázar, J; Alonso, JM; Alvarez, RM; Andrés, JI; Bakker, MH; Biesmans, I; Cid, JM; De Lucas, AI; Drinkenburg, W; Fernández, J; Font, LM; Iturrino, L; Langlois, X; Lenaerts, I; Martínez, S; Megens, AA; Pastor, J; Pullan, S; Steckler, T | 1 |
| Goeders, NE; Runyon, SP; Schmoutz, CD; Zhang, Y | 1 |
| Arnaud, C; Blaise, S; Boutonnat, J; Cracowski, JL; Godin-Ribuot, D; Kotzki, S; Roustit, M | 1 |
| Barbera, V; Bonfanti, R; Broggini, GL; Campisi, A; Chiacchio, U; Gazzola, S; Parenti, R; Romeo, G | 1 |
| Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
| Chen, K; Chen, L; Gao, Y; Huang, H; Li, S; Liu, F; Wang, W; Xie, M; Xue, S; Zhang, M | 1 |
| Honkimaa, A; Hyöty, H; Sioofy-Khojine, AB | 1 |
| Albanese, V; Amendola, G; Bernardi, T; Calò, G; Cosconati, S; Fabbri, M; Fantinati, A; Ferrari, F; Guerrini, R; Marzola, E; Pacifico, S; Preti, D; Reinscheid, RK; Ruzza, C; Sturaro, C; Trapella, C | 1 |
| Feng, Y; Fu, X; Li, Z; Lin, F; Lv, J; Mao, Q; Mou, Y; Wang, S; Yang, Y; Zhang, B; Zhang, L; Zhang, P; Zhao, J | 1 |
3 review(s) available for oxazoles and pyrazines
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
[Dipeptidylpeptidase IV inhibitors and dual action PPAR-agonists].
Topics: Adamantane; Adenosine Deaminase Inhibitors; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glycine; Glycoproteins; Humans; Hypoglycemic Agents; Nitriles; Oxazoles; Peroxisome Proliferator-Activated Receptors; Protease Inhibitors; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin | 2006 |
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
12 other study(ies) available for oxazoles and pyrazines
| Article | Year |
|---|---|
[Syntheses of radioactive cyclols as potential precursors of the peptide moiety of ergot alkaloids].
Topics: Acylation; Carbon Radioisotopes; Chromatography, Thin Layer; Cyclization; Ergot Alkaloids; Ergotamine; Mass Spectrometry; Oxazoles; Peptides; Pyrazines; Pyrroles | 1975 |
Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Male; Mice; Muscimol; Myoclonus; Oxazoles; Piperazines; Pyrazines; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Serotonin; Serotonin | 1981 |
A comparison of the analgesic activities of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP) and 6-chloro-2[1-piperazinyl]pyrazine (MK 212).
Topics: Analgesics; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Isoxazoles; Male; Mice; Morphine; Oxazoles; Pyrazines; Time Factors | 1983 |
Efficient, stereoselective synthesis of oxazolo[3,2-a]pyrazin-5-ones: novel bicyclic lactam scaffolds from the bicyclocondensation of 3-aza-1,5-ketoacids and amino alcohols.
Topics: Amino Alcohols; Aza Compounds; Cyclization; Keto Acids; Ketones; Lactams; Oxazoles; Oxidation-Reduction; Propanolamines; Propylene Glycols; Pyrazines; Stereoisomerism | 2003 |
Tricyclic isoxazolines: identification of R226161 as a potential new antidepressant that combines potent serotonin reuptake inhibition and alpha2-adrenoceptor antagonism.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents, Tricyclic; Humans; Isoxazoles; Male; Oxazoles; Pyrazines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors | 2007 |
Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats.
Topics: Animals; Cocaine; Male; Motivation; Oxazoles; Pyrazines; Rats; Rats, Wistar; Receptors, Neuropeptide; Self Administration; Yohimbine | 2012 |
Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats.
Topics: Acetates; Acrylamides; Animals; Data Interpretation, Statistical; Electric Stimulation; Electrodes; Guanylate Cyclase; In Vitro Techniques; Iontophoresis; Male; Nitrosamines; Oxazoles; Platelet Aggregation Inhibitors; Pyrazines; Pyrazoles; Rats; Rats, Wistar; Receptors, Epoprostenol; Regional Blood Flow; Skin | 2013 |
Synthesis and biological evaluation of 1,7,8,8a-tetrahydro-3H-oxazolo[3,4-a]pyrazin-6(5H)-ones as antitumoral agents.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Humans; Oxazoles; Pyrazines; Structure-Activity Relationship | 2013 |
Liguzinediol Enhances the Inotropic Effect of Rat Hearts via Inhibition of Protein Phosphatase (PP1 and PP2A) Activities.
Topics: Animals; Calcium Channel Agonists; Cardiotonic Agents; Enzyme Inhibitors; Heart; Male; Marine Toxins; Organ Culture Techniques; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Pyrazines; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2017 |
A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses.
Topics: A549 Cells; Amides; Antiviral Agents; Azithromycin; Benzimidazoles; Coxsackievirus Infections; Diabetes Mellitus, Type 1; Drug Repositioning; Enterovirus B, Human; Fluoxetine; Guanidine; Humans; Immunoglobulin G; Lovastatin; Oxadiazoles; Oxazoles; Oximes; Pyrazines; Ribavirin; Sulfonamides | 2020 |
Structure-Activity Relationship Studies on Oxazolo[3,4-
Topics: Animals; HEK293 Cells; Humans; Locomotion; Mice, Knockout; Molecular Docking Simulation; Molecular Structure; Oxazoles; Protein Binding; Pyrazines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Structure-Activity Relationship | 2021 |
Scaffold hopping of celastrol provides derivatives containing pepper ring, pyrazine and oxazole substructures as potent autophagy inducers against breast cancer cell line MCF-7.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Oxazoles; Pentacyclic Triterpenes; Pyrazines; Structure-Activity Relationship; Zebrafish | 2022 |