oxazoles has been researched along with oxazolidine in 197 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (14.72) | 18.7374 |
| 1990's | 7 (3.55) | 18.2507 |
| 2000's | 65 (32.99) | 29.6817 |
| 2010's | 79 (40.10) | 24.3611 |
| 2020's | 17 (8.63) | 2.80 |
| Authors | Studies |
|---|---|
| Mu, L; Qi, JA; Zhang, QD | 1 |
| Ahn, MS; DeGraff, WG; Krishna, MC; Mitchell, JB; Russo, A; Samuni, A; Samuni, U | 1 |
| Barth, A; Brandt, W; Ludwig, O; Thondorf, I | 1 |
| Bakhtiar, R; Hop, CE; Walker, RB | 1 |
| Silverman, RB | 1 |
| Bakhtiar, R; Brasfield, KL; Dholakia, VN; Walker, RB | 1 |
| Fukazawa, T; Iio, Y; Ishibashi, K; Itoh, K; Kurata, H; Mukaiyama, O; Nakajima, K; Nishi, T; Satoh, Y; Sugioka, Y; Yamaguchi, T | 1 |
| Carré, F; Monge, S; Pavia, AA; Roque, JP; Sélambarom, J; Verducci, J | 1 |
| Keller, M; Miller, AD | 1 |
| Adam, W; Schambony, SB | 1 |
| Burke, TR; Gao, Y; Kelley, JA; Liu, DG; Wang, X | 1 |
| Guz, NR; Phillips, AJ | 1 |
| Akao, A; Hiraga, S; Jona, H; Kato, Y; Mase, T; Niiyama, K; Okada, S; Tomimoto, K; Tsuchiya, Y | 1 |
| Eiraku, T; Eto, M; Hirashima, A; Kuwano, E; Shigeta, Y; Taniguchi, E | 1 |
| Bennett, EM; Cottet, SE; Ealick, SE; Ekstrom, JL; Pegg, AE; Tolbert, WD; Zhang, Y | 1 |
| Girniene, J; Holman, GD; Rollin, P; Sackus, A; Tatibouët, A; Yang, J | 1 |
| Downey, CW; Evans, DA; Hubbs, JL | 1 |
| Kudrej-Gibas, E; Maślińska-Solich, J | 1 |
| Evans, DA; Fandrick, KR; Lam, HW; Scheidt, KA; Wu, J | 1 |
| BERTCHER, EL; TAYLOR, JD | 1 |
| BROWN, WC; GOODMAN, LS; SWINYARD, EA | 1 |
| CURLETTO, R; GASPERONI, G | 1 |
| LAWRENCE, DE | 1 |
| BUTLER, TC; MAHAFFEE, C; MAHAFFEE, D | 1 |
| ISCH, F | 1 |
| FRAENKEL-CONRAT, H | 1 |
| SPEIL, W; STROTZKA, H | 1 |
| BALDWIN, RW | 1 |
| GROSSI-BIANCHI, ML; PISTONE, FM | 1 |
| BUTLER, TC | 2 |
| BUTLER, TC; WADDELL, WJ | 1 |
| SCHMIDT, L | 1 |
| JANKE, W; LIENERT, GA | 1 |
| HOLECKOVA, E; SERVIT, Z | 1 |
| FRIEDEL, B; LEMPP, R | 1 |
| BERGSTRAND, A; BERGSTRAND, CG; ENGSTROM, N; HERRLIN, KM | 1 |
| PUECH, J; ROBIN, C; RUFFIOT, A | 1 |
| SCHILKEN, K; SCHNEIDER, W | 1 |
| GARCIAGUERRA, CM | 1 |
| KOJIMA, M; TAGUCHI, T | 1 |
| De Jesus, K; Kimball, DB; Michalczyk, R; Moody, E; Ollivault-Shiflett, M; Silks, LA | 1 |
| BUTTER, AJ | 1 |
| BATTEUR, J; DUPAS, J; LESPAGNOL, A; MARINACCE, P; MERCIER, J | 1 |
| NABARRO, JD; ROSENHEIM, ML | 1 |
| TEGELAERS, WH; TIDDENS, H | 1 |
| GOODMAN, LS; SCHIFFMAN, DO; SWINYARD, EA | 1 |
| HERNANDEZ PENICHE, J | 1 |
| Casoni, D; Darabantu, M; Maiereanu, C; Sârbu, C | 1 |
| Gartner, ZJ; Li, X; Liu, DR; Tse, BN | 1 |
| MARINACCE, P; MERCIER, J | 1 |
| Gibas, E; Maślińska-Solich, J | 1 |
| Hitesh, NA; Mallesha, H; Rangappa, KS; Sadashiva, MP | 1 |
| García-Tellado, F; González-Cruz, D; Marrero-Tellado, JJ; Santos-Expósito, A; Tejedor, D | 1 |
| Abedini, A; Raleigh, DP | 1 |
| Bégué, JP; Bonnet-Delpon, D; Crousse, B; Legros, J | 1 |
| Dondoni, A; Giovannini, PP; Perrone, D | 1 |
| Meyers, AI | 1 |
| Denhez, C; Joosten, A; Szymoniak, J; Vasse, JL | 1 |
| Betson, MS; Clayden, J; Helliwell, M; Johnson, P; Lai, LW; Pink, JH; Stimson, CC; Vassiliou, N; Westlund, N; Yasin, SA; Youssef, LH | 1 |
| Clayden, J; Foricher, YJ; Helliwell, M; Johnson, P; Mitjans, D; Vinader, V | 1 |
| Goldstein, S; Hideg, K; Merenyi, G; Samuni, A | 1 |
| Notte, GT; Sammakia, T | 1 |
| Claridge, TD; Fairbanks, AJ; Moir, JW; Rising, TW | 1 |
| Kadono, T; Kagami, S; Komine, M; Matsushima, K; Nagakubo, D; Nakamura, K; Nakayama, T; Saeki, H; Shimazu, K; Sugaya, M; Tamaki, K; Tsunemi, Y; Yoshie, O | 1 |
| Disadee, W; Ishikawa, T; Kawahata, M; Yamaguchi, K | 1 |
| Forgó, P; Hornyák, M; Howarth, NM; Kele, Z; Kovács, L | 1 |
| Choudhury, SD; DasGupta, S; Norris, GE | 1 |
| Gao, Q; Yan, YL; Yang, D; Zheng, BF; Zhu, NY | 1 |
| Barroso, S; Blay, G; Pedro, JR | 1 |
| Blanco, JL; Fernández, JM; Mellet, CO; Sylla, B | 1 |
| Choudhury, SD; DasGupta, S; Haverkamp, RG; Norris, GE | 1 |
| Evans, DA; Fandrick, KR; Scheidt, KA; Song, HJ; Xu, R | 1 |
| Beddow, JE; Davies, SG; Ling, KB; Roberts, PM; Russell, AJ; Smith, AD; Thomson, JE | 1 |
| Becker, N; Carreira, EM | 1 |
| Barcan, GA; Kwon, O; Sriramurthy, V | 1 |
| Edwards, DJ; House, D; Sheldrake, HM; Stone, SJ; Wallace, TW | 1 |
| Dallemagne, P; Omran, Z; Rault, S | 1 |
| Bottle, SE; Coote, ML; Hodgson, JL; Namazian, M | 1 |
| Avalos, M; Babiano, R; Cintas, P; Jiménez, JL; Light, ME; Palacios, JC; Pérez, EM | 1 |
| Brigaud, T; Pytkowicz, J; Sini, G; Tessier, A | 1 |
| Brigaud, T; Lahmar, N; Pytkowicz, J; Tessier, A | 1 |
| Ischay, MA; Michaelis, DJ; Yoon, TP | 1 |
| Chu, FL; Yaylayan, VA | 1 |
| Andersson, PG; Diéguez, M; Mazuela, J; Pàmies, O; Verendel, JJ | 1 |
| Sattely, ES; Walsh, CT | 1 |
| Kobayashi, S; Saito, S; Seki, K; Tsubogo, T; Yamashita, Y | 1 |
| Barrett, JF; Burgess, B; Masurekar, P; Onishi, R; Singh, SB; Ushio, M; Zhang, C; Zink, DL | 1 |
| Fraga, MG; Pérez, AR; Porto, RM; Vidal, MT | 1 |
| Fischer, R; Kaufmann, DE; Namyslo, JC; Zapol'skii, VA | 1 |
| Giampietro, NC; Hay, MB; Lemen, GS; Wolfe, JP | 1 |
| Fröhlich, R; Husain, SM; Schepmann, D; Wünsch, B | 1 |
| An, Y; Beehler, BC; Bryson, JA; DiMarco, J; Egan, D; Fura, A; Golla, R; Gougoutas, JZ; Grover, GJ; Hamann, LG; Kish, KF; Krystek, SR; Kuhns, JE; Li, YX; Lupisella, JA; Nirschl, AA; Ostrowski, J; Sack, JS; Seethala, R; Simpkins, LM; Sleph, PG; Sutton, JC; Vyas, VP; Zahler, R; Zou, Y | 1 |
| Beaudet, I; Coeffard, V; Evain, M; Le Grognec, E; Quintard, JP | 1 |
| Dai, L; Lu, M; Zhong, G; Zhu, D | 1 |
| Donahue, MG; Hong, KB; Johnston, JN | 1 |
| Banerjee, A; Banu, KS; Bhattacharya, S; Chattopadhyay, T; Das, D; Ganguly, S; Patra, A; Zangrando, E | 1 |
| Alladoum, J; Kadouri-Puchot, C; Mangeney, P; Roland, S; Vrancken, E | 1 |
| Ahmed, E; Condamine, E; Conlon, JM | 1 |
| Bates, RW; Lu, Y | 1 |
| Emge, TJ; Mal, R; Mittal, N; Seidel, D | 1 |
| Abdullah, AF; Miskelly, GM | 1 |
| Brigaud, T; Chaume, G; Lubin, H; Pytkowicz, J; Tessier, A | 1 |
| Craik, DJ; Iskander, MN; Moloney, GP | 1 |
| Chiacchio, U; Corsaro, A; Merino, P; Romeo, G | 1 |
| Al-Dabbagh, B; Bouhss, A; Ichikawa, S; Ii, K; Matsuda, A | 1 |
| Barbeau, O; Brigaud, T; Chaume, G; Lesot, P | 1 |
| Kohari, Y; Kwon, E; Matsuyama, H; Nakano, H; Osone, K; Seki, C; Takano, N; Takeshita, M | 1 |
| Bello, D; Catti, F; Isambert, N; Kielland, N; Lavilla, R; Luque, FJ; Soteras, I | 1 |
| Graham, TH | 1 |
| Brigaud, T; Inagaki, S; Marinkovic, S; Pytkowicz, J; Stéphany, O | 1 |
| da Silva, AD; de Souza, MV; Gonçalves, RS; Kaiser, CR; Lourenço, MC; Wardell, JL; Wardell, SM | 1 |
| Joosten, A; Lambert, E; Szymoniak, J; Vasse, JL | 1 |
| Cikoš, A; Dilović, I; Gembarovski, D; Ištuk, ZM; Kragol, G; Lazarevski, G; Matković-Čalogović, D | 1 |
| Huang, H; Jin, Z; Liang, X; Wang, X; Ye, J | 1 |
| Booker-Milburn, KI; Cox, B; Elliott, LD; Lloyd-Jones, GC; Wrigglesworth, JW | 1 |
| Wolf, C; Xu, H | 2 |
| Wang, Z; Yu, L; Zhou, W | 1 |
| Huang, W; Li, J; Wang, LX | 1 |
| Frenzel, E; Niederweis, M; Schmidt, S; Steinhauer, K | 1 |
| Koh, M; Park, SB; Srivastava, AK | 1 |
| Ávalos, M; Babiano, R; Cintas, P; Jiménez, JL; Martínez, RF; Palacios, JC; Pérez, EM | 1 |
| Carenza, E; Degennaro, L; Florio, S; Luisi, R; Mansueto, R; Pratt, LM; Rizzi, R | 1 |
| Brutto, PE; Mandal, AB; Ramanaiah, B; Ramesh, R; Saravanan, P; Siddhartha, G; Sundarapandiyan, S | 1 |
| Fan, YC; Kwon, O | 1 |
| Mahler, G; Saiz, C; Wipf, P | 1 |
| Li, H; Wang, F; Wang, L; Wu, JW; Yang, GF; Yang, WC | 1 |
| Kumar, AS; Kumar, PV; Ramu, P; Selvam, TP | 1 |
| Ward, AF; Wolfe, JP | 1 |
| Grote, RE; Jarvo, ER; Shaghafi, MB | 1 |
| Bezerra, FA; Costa, T; de Souza, MV; Gonçalves, RS; Henriques, Md; Kaiser, CR; Lourenço, MC; Wardell, JL; Wardell, SM | 1 |
| Brigaud, T; Chelain, E; Simon, J | 1 |
| Kang, W; Wang, W; Wei, P; Xu, H; Zhang, B; Zhi, X | 1 |
| Chen, WB; Han, WY; Han, YY; Wu, ZJ; Yuan, WC; Zhang, XM | 1 |
| Carbery, DR; Fairhurst, NW; Mahon, MF; Munday, RH | 1 |
| Edler, M; Ellmaier, L; Griesser, T; Rossegger, E; Schenk, V; Weidinger, G; Wiesbrock, F | 1 |
| Bar, E; Ben-Shabat, S; Dudai, N; Krizevski, R; Levy, A; Lewinsohn, E; Sitrit, Y | 1 |
| Ciolino, LA; Ge, X; Kee, CL; Lai, CS; Low, MY | 1 |
| Cano, I; Gómez-Bengoa, E; Landa, A; Maestro, M; Mielgo, A; Oiarbide, M; Olaizola, I; Palomo, C | 1 |
| Anwar, M; Moloney, MG | 1 |
| Gupta, S; Kamal, A; Narasimha Rao, MP; Shaik, AB; Shetti, RV; Swapna, P | 1 |
| Karthik, G; Rajasekaran, T; Reddy, BV; Sridhar, B | 1 |
| Brigaud, T; Dupuis, C; Lubin, H; Pytkowicz, J | 1 |
| Brodney, MA; Coffman, KJ; Lee, C; Miller, E; Obach, RS; Rapp, T; Ryder, TF; Sawant-Basak, A; Tseng, E; Vanase-Frawley, MA; Walker, GS; Wong, JW | 1 |
| Balsells, J; Bateman, T; Brown, P; Chu, HD; Clemas, J; Contino, L; Cox, JM; Crespo, A; Crook, M; Garcia-Calvo, M; Gibson, J; Lisnock, J; Shen, HC; Sinclair, P; Tong, X; Wiltsie, J; Wu, Z; Xu, L; Yang, C; Zamlynny, B; Zhou, G | 1 |
| Johnson, T; Lautens, M | 1 |
| Arai, T; Ogino, Y; Sato, T | 1 |
| Bomfim, Ida S; Cavalcanti, BC; de Souza, MV; Goncalves, RS; Pessoa, C; Rodrigues, FA; Wardell, JL; Wardell, SM | 1 |
| Carreira, EM; Diethelm, S; Schoenebeck, F | 1 |
| Bharti, VD; Gupta, SP; Kumar, H | 1 |
| Antilla, JC; Nimmagadda, SK; Zhang, Z | 1 |
| Inokuma, T; Kazumi, N; Kobayashi, Y; Stadler, M; Takemoto, Y; Tsuji, N | 1 |
| Dzuba, SA; Isaev, NP; Konov, KB | 1 |
| Agerbirk, N; Olsen, CE | 1 |
| Brigaud, T; Lensen, N; Marais, J | 1 |
| Dong, M; Lowary, TL; Wang, L | 1 |
| Brigaud, T; Chaume, G; Lubin, H; Pytkowicz, J; Sizun-Thomé, G | 1 |
| Augusto, MT; Castanho, MA; Gonçalves, S; Hollmann, A; Lee, B; Santos, NC | 1 |
| Gong, P; Jiang, M; Ma, L; Wu, S; Zhang, K; Zhang, X; Zhao, Y; Zhou, S | 1 |
| Ban, S; Black, T; Fukuda, H; Fukuda, Y; Gill, C; Kaelin, DE; Kishii, R; Lagrutta, A; Meinke, PT; Miesel, L; Nargund, R; Nishimura, A; Ohata, K; Olsen, DB; Peng, X; Shibue, T; Singh, SB; Takano, H; Takei, M; Takeuchi, T; Tan, CM; Wang, X; Wei, C; Wu, J | 1 |
| Abberley, JP; de Souza, MV; Harrison, WT; Nogueira, TC; Pinheiro, AC; Wardell, JL | 1 |
| Barthel, BL; Koch, GG; Koch, TH; Mooz, EL; Wiener, LE | 1 |
| Ichikawa, S | 1 |
| Cox, DP; Gutmann, B; Kappe, CO; Weigl, U | 1 |
| Abbadi, BL; Basso, LA; Campos, MM; de Souza, MV; Gonçalves, RS; González-Martín, J; López-Gavín, A; Rodrigues-Junior, VS; Santos, DS; Trindade, RV; Tudó, G; Villela, AD | 1 |
| Alves, RJ; Andrade, SF; Joaquim, AR; Oliveira, BG; Pereira, LC; Ramos, JP; Souza-Fagundes, EM; Steppe, M | 1 |
| Gonzalez Garcia, LE; MacGregor-Ramiasa, M; Vasilev, K; Visalakshan, RM | 1 |
| Radulović, NS; Randjelović, PJ; Stojanović, NM; Todorovska, MM; Zlatković, DB | 1 |
| Duvvuri, S; Kadar, EP; Kimoto, E; Lin, J; Nicholas, T; Obach, RS; Sawant-Basak, A; Tremaine, LM | 1 |
| Dogan, I; Erol Gunal, S; Gokhan Kelekci, N; Sag Erdem, S; Teke Tuncel, S; Ucar, G; Yuce Dursun, B | 1 |
| Chan, HN; Li, HW; Li, Y; Poon, CY; Wong, MS; Xu, D | 1 |
| Becheker, I; Bechlem, K; Belhani, B; Berredjem, H; Berredjem, M; Bouaziz, Z; Bouzina, A; Le Borgne, M; Lebreton, J; Marminon, C | 1 |
| Benfodda, Z; Benimélis, D; Meffre, P; Reginato, G | 1 |
| Qiu, X; Sun, S; Tang, L; Wang, W; Zhao, Z | 1 |
| Codeceira, GHR; da Silva, RR; de Andrade, CAS; de Lima, MDCA; de Oliveira, MDL; Pitta, IDR; Rocha, FS | 1 |
| Li, L; Ma, Y; Shang, C; Shang, L; Wang, B; Yang, P; Yin, Z; Zhai, Y | 1 |
| Collum, DB; Zhang, Z | 1 |
| Garrido Frenich, A; López-Ruiz, R; Romero-González, R | 1 |
| Fu, Y; Gao, S; Jiang, JY; Li, CY; Liu, YY; Ye, F; Zhao, LX | 1 |
| Higashiyama, K | 1 |
| Li, Y; Xie, Z; Yang, X; Zhang, Y; Zhu, Y | 1 |
| He, H; Li, YG; Ren, L; Wu, X; Zhu, CF; Zhu, ZH | 1 |
| Fu, Y; Gao, S; Hoang, MT; Li, N; Ma, X; Wang, ZW; Ye, F; Zhai, Y; Zhang, YY; Zhao, LX | 1 |
| Cunha, EGC; da Rocha Pitta, I; da Rocha Pitta, MG; de Mello, GSV; de Melo Rêgo, MJB; de Oliveira, JF; do Carmo Alves de Lima, M; Rizzo, JÂ; Santos, RVC | 1 |
| Liu, H; Luck, RL; Mazi, W; Tajiri, M; Wan, S; Xia, S; Yan, Y; Zhang, Y | 1 |
| Abdelhay, E; da Rocha Pitta, I; da Rocha Pitta, MG; de Melo Rêgo, MJB; de Sena, WLB; do Carmo Alves de Lima, M; do Nascimento Carvalho, LV; Pereira, MC; Pizzatti, L; Souza, GHMF | 1 |
| Äärelä, A; Aho, A; Korhonen, H; Virta, P | 1 |
| Mazhukin, DG; Zaytseva, EV | 1 |
| Iwata, YT; Kanamori, T; Kuwayama, K; Okada, Y; Segawa, H; Tsujikawa, K; Yamamuro, T | 1 |
| Ghosh, A; Mondal, B; Pan, SC; Parida, C | 1 |
| Basu, AJ; Ghosh, AK; Hsu, CS; Yadav, M | 1 |
| Chung, K; Kim, YG; Kwon, H; Lee, B; Lee, Y; Seo, Y | 1 |
| Kederienė, V; Rousseau, J; Šačkus, A; Schuler, M; Tatibouët, A | 1 |
| Fu, H; Tan, J; Wang, C; Zhang, X | 1 |
| Cintas, P; Light, ME; Matamoros, E; Palacios, JC | 1 |
| Christensen, KE; Genov, M; Li, X; Moloney, MG; Panduwawala, T; Pretsch, A; Pretsch, D; Saney, L | 1 |
5 review(s) available for oxazoles and oxazolidine
| Article | Year |
|---|---|
The chemistry of trifluoromethyl imines and related acetals derived from fluoral.
Topics: Acetaldehyde; Acetals; Chemical Phenomena; Chemistry; Cyclization; Imines; Molecular Conformation; Oxazoles | 2005 |
Chemical synthesis of heterocyclic-sugar nucleoside analogues.
Topics: Carbohydrates; Dioxolanes; Heterocyclic Compounds; Isoxazoles; Nucleosides; Oxazoles; Pyrrolidines; Sulfhydryl Compounds; Sulfides; Thiazolidines | 2010 |
Asymmetric catalysis with chiral oxazolidine ligands.
Topics: Catalysis; Ligands; Oxazoles; Stereoisomerism | 2011 |
Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon.
Topics: Biphenyl Compounds; Catalysis; Glycine; Oxazoles; Stereoisomerism | 2018 |
Spirocyclic Nitroxides as Versatile Tools in Modern Natural Sciences: From Synthesis to Applications. Part I. Old and New Synthetic Approaches to Spirocyclic Nitroxyl Radicals.
Topics: Imidazoles; Imidazolidines; Morpholines; Natural Science Disciplines; Nitrogen Oxides; Oxazoles; Piperidines; Pyrrolidines; Reducing Agents | 2021 |
192 other study(ies) available for oxazoles and oxazolidine
| Article | Year |
|---|---|
[Synthesis of oxazolidines from ephedrines as potential prodrugs].
Topics: Ephedrine; Hydrolysis; Oxazoles; Prodrugs; Structure-Activity Relationship | 1992 |
Biologically active metal-independent superoxide dismutase mimics.
Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Cytochrome c Group; DNA; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Nitrogen Oxides; Oxazoles; Oxidation-Reduction; Superoxide Dismutase | 1990 |
A new mechanism in serine proteases catalysis exhibited by dipeptidyl peptidase IV (DP IV)--Results of PM3 semiempirical thermodynamic studies supported by experimental results.
Topics: Binding Sites; Computer Simulation; Dipeptidyl Peptidase 4; Isomerism; Models, Chemical; Oxazoles; Serine Endopeptidases; Thermodynamics | 1996 |
Effect of cyclodextrins on the hydrolysis of an oxazolidine prodrug of (1R,2S)-(-)-ephedrine-cis-2-(4-methoxyphenyl)-3, 4-dimethyl-5-phenyloxazolidine.
Topics: Cyclodextrins; Ephedrine; Hydrolysis; Kinetics; Mass Spectrometry; Oxazoles; Prodrugs | 1997 |
Oxazolidinones, dihydrofuranones, and pyrrolidinones as inactivators and substrates of monoamine oxidase B: approaches to the design of antiparkinsonian agents.
Topics: Antiparkinson Agents; Monoamine Oxidase Inhibitors; Oxazoles; Pyrrolidinones | 1997 |
Effect of hydroxypropyl-beta-cyclodextrin on the central stimulant activity of (-)-ephedrine and an oxazolidine prodrug in rats.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adrenergic Agents; Animals; beta-Cyclodextrins; Cyclodextrins; Dose-Response Relationship, Drug; Ephedrine; Male; Mass Spectrometry; Oxazoles; Prodrugs; Rats; Rats, Sprague-Dawley | 1998 |
Combined NK1 and NK2 tachykinin receptor antagonists: synthesis and structure-activity relationships of novel oxazolidine analogues.
Topics: Animals; Guinea Pigs; Ileum; Inhibitory Concentration 50; Kinetics; Lung; Models, Chemical; Oxazoles; Receptors, Tachykinin; Structure-Activity Relationship | 1999 |
Anomeric effects in non-carbohydrate compounds: conformational differences between the oxazolidine rings of a cis-fused bicyclic system.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Carbohydrate Conformation; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazoles; Stereoisomerism; Thermodynamics | 2000 |
Access to the inaccessible sequence of cpn 60.1 (195-217) by temporary oxazolidine protection of selected amide bonds.
Topics: Amides; Chaperonin 60; Dipeptides; Oxazoles; Peptide Fragments | 2001 |
Diastereoselective epoxidation of oxazolidine-substituted alkenes by dimethyldioxirane and m-chloroperbenzoic acid: pi-facial control through hydrogen bonding by the urea functionality.
Topics: Alkenes; Amines; Catalysis; Chlorobenzoates; Epoxy Compounds; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Oxazoles; Stereoisomerism; Structure-Activity Relationship; Urea | 2001 |
Enantioselective synthesis of N(alpha)-Fmoc protected (2S,3R)-3-phenylpipecolic acid. A constrained phenylalanine analogue suitably protected for solid-phase peptide synthesis.
Topics: Carboxylic Acids; Catalysis; Fluorenes; Molecular Conformation; Molecular Structure; Oxazoles; Peptides; Phenylalanine; Pipecolic Acids; Stereoisomerism | 2002 |
Practical and highly selective oxazolidinethione-based asymmetric acetate aldol reactions with aliphatic aldehydes.
Topics: Aldehydes; Biological Factors; Oxazoles; Sparteine; Stereoisomerism; Thiones; Titanium | 2002 |
Asymmetric synthesis of a selective endothelin A receptor antagonist.
Topics: Endothelin Receptor Antagonists; Lithium Compounds; Molecular Conformation; Oxazoles; Receptor, Endothelin A; Technology, Pharmaceutical | 2002 |
Three-dimensional common-feature hypotheses of inhibitors of calling behaviour and in vitro [14C]acetate incorporation by pheromone glands of Plodia interpunctella.
Topics: Acetates; Aniline Compounds; Animals; Behavior, Animal; Carbon Radioisotopes; Female; Larva; Lepidoptera; Male; Models, Molecular; Molecular Structure; Octopamine; Oxazoles; Pheromones; Pupa; Thiazoles; Thiazolidines | 2002 |
Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.
Topics: Adenosylmethionine Decarboxylase; Alanine; Binding Sites; Buffers; Catalysis; Computer Simulation; Crystallography, X-Ray; Enzyme Precursors; Glutamine; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Oxazoles; Oxygen; Protein Processing, Post-Translational; Putrescine; Serine; Tromethamine | 2003 |
Inhibition of the D-fructose transporter protein GLUT5 by fused-ring glyco-1,3-oxazolidin-2-thiones and -oxazolidin-2-ones.
Topics: Animals; Binding Sites; Carbon Radioisotopes; CHO Cells; Cricetinae; Fructose; Glucose Transporter Type 5; Kinetics; Monosaccharide Transport Proteins; Oxazoles; Protein Binding; Sorbose; Structure-Activity Relationship; Thiones | 2003 |
Ni(II) bis(oxazoline)-catalyzed enantioselective syn aldol reactions of N-propionylthiazolidinethiones in the presence of silyl triflates.
Topics: Alcohols; Ketones; Models, Molecular; Nickel; Organometallic Compounds; Oxazoles; Silanes; Stereoisomerism; Thiazoles | 2003 |
Electrospray mass spectrometry determination of poly(oxazolidine acetal).
Topics: Acetals; Oxazoles; Polymers; Spectrometry, Mass, Electrospray Ionization | 2003 |
Enantioselective indole Friedel--Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes.
Topics: Alkylation; Catalysis; Indoles; Mesylates; Models, Molecular; Organophosphonates; Oxazoles; Pyridines; Scandium; Stereoisomerism | 2003 |
The determination and distribution of trimethadione (tridione) in animal tissues.
Topics: Animals; Humans; Oxazoles; Trimethadione | 1952 |
Comparative assays of antiepileptic drugs in mice and rats.
Topics: Animals; Anticonvulsants; Barbiturates; Biological Assay; Hydantoins; Mice; Oxazoles; Rats; Seizures; Urea | 1952 |
[Secondary hemotoxic effect of tridione].
Topics: Hematopoietic System; Oxazoles; Trimethadione | 1952 |
Near fatal hemolytic anemia during anti-epileptiform convulsion therapy with tridione.
Topics: Anemia, Hemolytic; Animals; Dog Diseases; Dogs; Epilepsy; Oxazoles; Seizures; Trimethadione | 1952 |
Metabolic demethylation of 3, 5, 5-trimethyl-2, 4-oxazolidinedione (trimethadione, tridione).
Topics: Anticonvulsants; Oxazoles; Trimethadione | 1952 |
[Therapy of epilepsies].
Topics: Barbiturates; Epilepsy; Humans; Hydantoins; Neurosurgery; Neurosurgical Procedures; Oxazoles | 1952 |
The reaction of proteins with 14C-labelled N-carboxyleucine anhydride.
Topics: Anhydrides; Leucine; Oxazoles; Proteins | 1953 |
[Oxazolidine therapy of petit mal].
Topics: Anticonvulsants; Epilepsy; Oxazoles | 1953 |
The dione drugs in petit mal seizures.
Topics: Epilepsy; Epilepsy, Absence; Humans; Oxazoles; Seizures | 1953 |
[Another case of petit mal of organic origin: endocraniosis; dangers of oxazolidinedione therapy].
Topics: Anticonvulsants; Epilepsy; Epilepsy, Absence; Hyperostosis Frontalis Interna; Oxazoles | 1954 |
Metabolic demethylation of 3,5-dimethyl-5-ethyl 2,4-oxazolidinedione (paramethadione, paradione).
Topics: Anticonvulsants; Body Fluids; Humans; Oxazoles; Urine | 1955 |
A pharmacological comparison of the optical isomers of 5-ethyl-5-methyl-2,4-oxazolidinedione and of 3,5-dimethyl-5 ethyl-2,4-oxazolidinedione (paramethadione, paradione).
Topics: Anticonvulsants; Isomerism; Oxazoles | 1955 |
[5-Phenyl-2-imino-4-oxo-oxazolidine, a central stimulant substance].
Topics: Central Nervous System; Central Nervous System Stimulants; Oxazoles; Oxotremorine | 1956 |
[Pharmaco-psychological experiments with 5-phenyl-2-imino-4-oxo-oxazolidine].
Topics: Oxazoles; Oxotremorine | 1957 |
[Experience with the adaptation of explanted tissues to an anticonvulsant (3,5,5-trimethyl-oxazolidine-2, 4-dione, trimedal) and to phenobarbital].
Topics: Acclimatization; Adaptation, Physiological; Anticonvulsants; Oxazoles; Phenobarbital; Tissue Culture Techniques | 1958 |
[Grand mal provocation in the treatment of petit mal in children with oxazolidines or succinimides and its therapeutic consequences].
Topics: Anticonvulsants; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Infant; Oxazoles; Pyrrolidinones; Seizures; Succinimides | 1962 |
Renal histology during treatment with oxazolidine-diones (trimethadione, ethadione, and paramethadione).
Topics: Anticonvulsants; Epilepsy; Humans; Kidney; Kidney Function Tests; Kidney Glomerulus; Nephrotic Syndrome; Oxazoles; Trimethadione | 1962 |
[Clinical and psychometric study of a new drug with neuro-stimulating properties: 5-phenyl-2-imino-4-oxazolidine (Deltamine)].
Topics: Humans; Mental Disorders; Oxazoles; Psychometrics | 1963 |
[OXAZOLIDINE AND SPIRO-OXAZOLIDINE FROM CALYCOTOMINE AND ON THE STRUCTURE OF 6,7-DIMETHOXY-3,4-DIHYDRO-ISOQUINOLINE-1-ACETIC ACID ETHYL ESTER].
Topics: Acetates; Alkaloids; Chemical Phenomena; Chemistry; Isoquinolines; Oxazoles; Oxyphenbutazone; Quinolines; Research; Spiro Compounds | 1963 |
[EXPERIENCES WITH 5-PHENYL-2-IMINO-4OXO-OXAZOLIDINE IN EPILEPSY].
Topics: Anticonvulsants; Central Nervous System Stimulants; Epilepsy; Oxazoles; Pharmacology; Toxicology | 1963 |
The effects of N-methylation in 5,5-disubstituted derivatives of barbituric acid, hydantoin, and 2-4-oxazolidinedione.
Topics: Anticonvulsants; Barbiturates; Hydantoins; Imidazoles; Methylation; Oxazoles | 1955 |
Studies in stereochemistry. IV. Alkanolamines. (4). Regular dl-2,5-diphenyl-4-methyloxazoline: the formation and action of methyl tosylate.
Topics: Amino Alcohols; Benzenesulfonates; Biphenyl Compounds; Oxazoles | 1955 |
Determining the solution state orientation of a Ti enolate via stable isotope labeling, NMR spectroscopy, and modeling studies.
Topics: Carbon Isotopes; Isotope Labeling; Isotopes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Organoselenium Compounds; Oxazoles; Selenium; Solutions; Thermodynamics; Titanium | 2003 |
Tridione compared with malidone in the treatment of petit mal.
Topics: Anticonvulsants; Epilepsy; Epilepsy, Absence; Humans; Oxazoles; Trimethadione | 1952 |
[Study of some derivatives of oxazolidinedione].
Topics: Oxazoles | 1952 |
Nephrotic syndrome complicating tridione (troxidone) therapy.
Topics: Humans; Nephrosis; Nephrotic Syndrome; Oxazoles; Trimethadione | 1952 |
[Tridione and nephrosis].
Topics: Epilepsy; Nephrosis; Oxazoles; Trimethadione | 1952 |
Effects of liver injury and nephrectomy on the anticonvulsant activity of oxazolidine-2,4-diones.
Topics: Anticonvulsants; Humans; Hydantoins; Liver; Nephrectomy; Oxazoles | 1952 |
[Action of paradione in epilepsy].
Topics: Epilepsy; Humans; Oxazoles | 1952 |
Quantitative structure-retention and retention-activity relationships of some 1,3-oxazolidine systems by RP-HPTLC and PCA.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Lipids; Molecular Structure; Oxazoles; Principal Component Analysis; Quantitative Structure-Activity Relationship | 2004 |
Translation of DNA into synthetic N-acyloxazolidines.
Topics: Acylation; Avidin; Biotin; Cyclization; DNA; Electrophoresis, Polyacrylamide Gel; Molecular Structure; Oxazoles; Protein Biosynthesis; Templates, Genetic | 2004 |
[Experimental analgesia action of some derivatives of oxazolidine-dione].
Topics: Analgesia; Oxazoles; Pain; Pain Management | 1952 |
Electrospray mass spectrometry studies of macromolecules containing 1,3-oxazolidine moieties.
Topics: Magnetic Resonance Spectroscopy; Oxazoles; Phthalic Acids; Polymers; Spectrometry, Mass, Electrospray Ionization | 2004 |
Synthesis and microbial inhibition study of novel 5-imidazolyl substituted isoxazolidines.
Topics: Anti-Bacterial Agents; Antifungal Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Isoxazoles; Mitosporic Fungi; Oxazoles; Structure-Activity Relationship | 2004 |
A modular, one-pot, four-component synthesis of polysubstituted 1,3-oxazolidines.
Topics: Oxazoles; Prodrugs | 2005 |
Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.
Topics: Amino Acid Sequence; Amyloid; Dipeptides; Humans; Islet Amyloid Polypeptide; Molecular Sequence Data; Oxazoles; Proline; Thiazoles | 2005 |
Cross-metathesis of C-allyl iminosugars with alkenyl oxazolidines as a key step in the synthesis of C-iminoglycosyl alpha-amino acids. A route to iminosugar containing C-glycopeptides.
Topics: Alkenes; Allyl Compounds; Amino Acids; Catalysis; Cyclization; Glycopeptides; Glycosides; Glycosylation; Imines; Molecular Structure; Oxazoles; Oxidation-Reduction; Stereoisomerism | 2005 |
Chiral oxazolines and their legacy in asymmetric carbon-carbon bond-forming reactions.
Topics: Carbon; Chelating Agents; Coenzymes; History, 20th Century; History, 21st Century; Ligands; Molecular Structure; NAD; Naphthalenes; Oxazoles; Stereoisomerism | 2005 |
Stereoselective synthesis of pyrrolidines from N-allyl oxazolidines via hydrozirconation-cyclization.
Topics: Cyclization; Molecular Structure; Oxazoles; Pyrrolidines; Stereoisomerism; Zirconium | 2005 |
Conformational preference in aromatic amides bearing chiral ortho substituents: its origin and application to relayed stereocontrol.
Topics: Alkylation; Amides; Crystallography, X-Ray; Ephedrine; Hydroxylation; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Oxazoles; Proline; Stereoisomerism; Sulfur; Thermodynamics | 2006 |
Conformational arm-wrestling: battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents.
Topics: Aldehydes; Amines; Benzamides; Crystallography, X-Ray; Ephedrine; Imidazolines; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxazoles; Proline; Safrole; Stereoisomerism; Trimethylsilyl Compounds | 2006 |
Structure-activity relationship of cyclic nitroxides as SOD mimics and scavengers of nitrogen dioxide and carbonate radicals.
Topics: Antioxidants; Carbonates; Cyclic N-Oxides; Free Radical Scavengers; Free Radicals; Hydrogen-Ion Concentration; Kinetics; Molecular Mimicry; Nitrogen Dioxide; Oxazoles; Oxidation-Reduction; Piperidines; Pulse Radiolysis; Pyrrolidines; Structure-Activity Relationship; Superoxide Dismutase; Superoxides | 2006 |
Kinetic resolution of protected alpha-amino acid derivatives by a chiral O-nucleophilic acyl transfer catalyst.
Topics: Amino Acids, Cyclic; Catalysis; Hydrogen Bonding; Imides; Kinetics; Oxazoles; Stereoisomerism; Thiones | 2006 |
Endohexosaminidase M: exploring and exploiting enzyme substrate specificity.
Topics: Amino Acids; Carbohydrate Conformation; Catalysis; Glycosylation; Hexosaminidases; Oxazoles; Substrate Specificity | 2006 |
CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli.
Topics: Acute Disease; Animals; Cells, Cultured; Chemokine CCL17; Chemokines, CC; Chronic Disease; Croton Oil; Dermatitis, Contact; Female; Gene Expression Regulation; Hypersensitivity; Interferon-gamma; Interleukin-4; Keratinocytes; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Transgenic; Oxazoles; Receptors, CCR4; Receptors, Chemokine; RNA, Messenger; Th2 Cells; Transcription Factors | 2006 |
Guanidinium ylide mediated aziridination: identification of a spiro imidazolidine-oxazolidine intermediate.
Topics: Aldehydes; Aziridines; Bromides; Guanidine; Hydrogen; Imidazolidines; Models, Molecular; Molecular Structure; Oxazoles; Stereoisomerism | 2006 |
Investigation of 1,3-dipolar cycloaddition reactions of unsaturated nitrones in ionic liquids.
Topics: Acetates; Azetidinecarboxylic Acid; Bridged Bicyclo Compounds; Galactose; Nitrogen Oxides; Oxazoles; Peptide Nucleic Acids; Stereoisomerism | 2006 |
Unravelling the mechanism of the interactions of oxazolidine A and E with collagens in ovine skin.
Topics: Amino Acids; Animals; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Circular Dichroism; Collagen; Cross-Linking Reagents; Glutaral; Mimosa; Oxazoles; Peptides; Sheep; Skin; Spectrometry, Mass, Electrospray Ionization; Tannins; Temperature | 2007 |
Copper(I)-catalyzed chlorine atom transfer radical cyclization reactions of unsaturated alpha-chloro beta-keto esters.
Topics: Catalysis; Chlorine; Copper; Cyclization; Esters; Free Radicals; Oxazoles | 2006 |
2-alkenoyl pyridine N-oxides, highly efficient dienophiles for the enantioselective Cu(II)-bis(oxazoline) catalyzed Diels-Alder reaction.
Topics: Alkenes; Aza Compounds; Catalysis; Chalcone; Copper; Cyclopentanes; Isomerism; Molecular Structure; Oxazoles; Pyridines | 2007 |
Synthesis of alpha- and beta-glycosyl isothiocyanates via oxazoline intermediates.
Topics: Carbohydrate Conformation; Glycosides; Isothiocyanates; Oxazoles | 2007 |
Effect of oxazolidine E on collagen fibril formation and stabilization of the collagen matrix.
Topics: Amino Acid Sequence; Collagen; Cross-Linking Reagents; Drug Stability; Microscopy, Electron, Scanning; Oxazoles; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Enantioselective Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes.
Topics: Alkylation; Catalysis; Crystallography, X-Ray; Imidazoles; Indoles; Mesylates; Models, Molecular; Organophosphonates; Oxazoles; Pyridines; Pyrroles; Scandium; Stereoisomerism | 2007 |
Asymmetric synthesis of beta2-amino acids: 2-substituted-3-aminopropanoic acids from N-acryloyl SuperQuat derivatives.
Topics: Alkylation; Amides; Amino Acids; beta-Alanine; Crystallography, X-Ray; Imaging, Three-Dimensional; Lithium; Models, Molecular; Molecular Structure; Oxazoles; Protons; Stereoisomerism | 2007 |
Hydroxyl-directed nitrile oxide cycloaddition reactions with cyclic allylic alcohols.
Topics: Cyclization; Hydrogen; Isomerism; Molecular Structure; Nitrites; Oxazoles; Oxides; Propanols | 2007 |
Bisphosphine-catalyzed mixed double-Michael reactions: asymmetric synthesis of oxazolidines, thiazolidines, and pyrrolidines.
Topics: Catalysis; Molecular Structure; Oxazoles; Phosphines; Pyrrolidines; Stereoisomerism; Thiazolidines | 2007 |
Kinetic and thermodynamic control of axial chirality in biaryl-derived fused oxazolidine lactams exploiting a centre-axis relay of unit efficiency.
Topics: Kinetics; Lactams; Models, Chemical; Molecular Structure; Oxazoles; Stereoisomerism; Thermodynamics; Time Factors | 2007 |
Synthesis of new bisaryl cyclopentathiophene and thienocyclopentoxazolidine derivatives as potential cytotoxic agents.
Topics: Antineoplastic Agents; Bromine; Cell Line, Tumor; Cross-Linking Reagents; Cyclopentanes; Drug Screening Assays, Antitumor; Humans; Hydrocarbons, Aromatic; Molecular Structure; Oxazoles; Thiophenes | 2007 |
One-electron oxidation and reduction potentials of nitroxide antioxidants: a theoretical study.
Topics: Antioxidants; Electrodes; Electrons; Models, Chemical; Nitrogen Oxides; Oxazoles; Oxidation-Reduction; Piperidines; Pyrrolidines; Thermodynamics | 2007 |
Chiral N-acyloxazolidines: synthesis, structure, and mechanistic insights.
Topics: Crystallography, X-Ray; Imines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Oxazoles; Rotation; Schiff Bases; Stereoisomerism | 2008 |
Fluorine... and pi...alkali metal interactions control in the stereoselective amide enolate alkylation with fluorinated oxazolidines (Fox) as a chiral auxiliary: an experimental and theoretical study.
Topics: Alkylation; Fluorine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metals, Alkali; Models, Theoretical; Oxazoles; Stereoisomerism | 2008 |
Highly diastereoselective synthetic route to enantiopure beta(2)-amino acids and gamma-amino alcohols using a fluorinated oxazolidine (Fox) as chiral auxiliary.
Topics: Amino Acids; Amino Alcohols; Molecular Conformation; Oxazoles; Stereoisomerism | 2008 |
Activation of N-sulfonyl oxaziridines using copper(II) catalysts: aminohydroxylations of styrenes and 1,3-dienes.
Topics: Aziridines; Catalysis; Cations, Divalent; Copper; Cyclopentanes; Hydroxylation; Oxazoles; Polyenes; Styrenes; Sulfones | 2008 |
Post-schiff base chemistry of the Maillard reaction: mechanism of imine isomerization.
Topics: Gas Chromatography-Mass Spectrometry; Imines; Isomerism; Maillard Reaction; Oxazoles; Schiff Bases; Spectroscopy, Fourier Transform Infrared | 2008 |
Chiral pyranoside phosphite-oxazolines: a new class of ligand for asymmetric catalytic hydrogenation of alkenes.
Topics: Alkanes; Alkenes; Catalysis; Hydrogenation; Iridium; Ligands; Oxazoles; Phosphites; Pyrans; Stereoisomerism | 2008 |
A latent oxazoline electrophile for N-O-C bond formation in pseudomonine biosynthesis.
Topics: Benzamides; Genes, Bacterial; Hydroxamic Acids; Ligases; Oxazoles; Pseudomonas; Siderophores | 2008 |
Development of catalytic asymmetric 1,4-addition and [3 + 2] cycloaddition reactions using chiral calcium complexes.
Topics: Amino Acids; Calcium; Carbon; Catalysis; Cyclization; Ligands; Magnetic Resonance Spectroscopy; Metals, Alkaline Earth; Molecular Structure; Oxazoles; Stereoisomerism | 2008 |
Isolation, structure, and antibacterial activity of thiazomycin A, a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa.
Topics: Actinomycetales; Anti-Bacterial Agents; Inhibitory Concentration 50; Microbial Sensitivity Tests; Oxazoles; Peptides, Cyclic; Staphylococcus aureus; Thiazoles | 2008 |
Qualitative confirmation procedure for ephedrines as acetonide derivatives in doping urine samples by gas chromatography/electron ionization mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Oxazoles; Propiophenones; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Urinalysis | 2009 |
Chemistry of polyhalogenated nitrobutadienes, 8: Nitropolychlorobutadienes--precursors for insecticidal neonicotinoids.
Topics: Butadienes; Guanidines; Halogenation; Imidazoles; Imidazolidines; Insecticides; Neonicotinoids; Nitro Compounds; Oxazoles; Pyridines; Thiazines; Thiazoles | 2009 |
Influence of hydroxylamine conformation on stereocontrol in Pd-catalyzed isoxazolidine-forming reactions.
Topics: Amination; Catalysis; Cyclization; Hydroxylamine; Molecular Conformation; Oxazoles; Palladium; Stereoisomerism | 2009 |
Asymmetric synthesis of enantiomerically pure 2-substituted tetrahydro-3-benzazepines and their affinity to sigma1 receptors.
Topics: Benzazepines; Cyclization; Hydrogen; Indans; Molecular Structure; Oxazoles; Stereoisomerism | 2009 |
N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.
Topics: Androgens; Animals; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Male; Models, Molecular; Molecular Conformation; Muscles; Oxazoles; Prostate; Rats; Substrate Specificity | 2009 |
Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines.
Topics: Ethanolamines; Glycine; Nitrogen; Organotin Compounds; Oxazoles; Propanolamines; Stereoisomerism; Substrate Specificity; Valine | 2009 |
Highly stereoselective one-pot synthesis of bicyclic isoxazolidines with five stereogenic centers by an organocatalytic process.
Topics: Bridged Bicyclo Compounds; Catalysis; Crystallography, X-Ray; Molecular Conformation; Nitrogen Oxides; Oxazoles; Stereoisomerism | 2009 |
Use of comparative triazolinium triflate fragmentation rates as a tool to assay relative competency of Brønsted bases in N-->N proton transfer.
Topics: Mesylates; Nitrogen; Oxazoles; Protons; Solvents; Triazines | 2009 |
Metal-assisted oxazolidine/oxazine ring formation in dinuclear zinc(II) complexes: synthesis, structural aspects, and bioactivity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Humans; Macrocyclic Compounds; Molecular Structure; Organometallic Compounds; Oxazines; Oxazoles; Zinc | 2009 |
Palladium-catalyzed cyclization of unsaturated beta-amino alcohols: a new access to enantiopure bicyclic oxazolidines.
Topics: Amino Alcohols; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Combinatorial Chemistry Techniques; Cyclization; Oxazoles; Palladium; Stereoisomerism | 2009 |
Antimicrobial properties of brevinin-2-related peptide and its analogs: Efficacy against multidrug-resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Amphibian Proteins; Anti-Infective Agents; Drug Resistance, Multiple, Bacterial; Erythrocytes; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Oxazoles; Peptides; Quantitative Structure-Activity Relationship | 2009 |
A formal synthesis of porantheridine and an epimer.
Topics: Acylation; Alkadienes; Alkaloids; Catalysis; Cyclization; Gold; Imines; Models, Chemical; Oxazoles; Silver; Solvents; Stereoisomerism | 2009 |
Facile synthesis of a chiral urea bridged bisoxazoline ligand and structural characterization of its bis-copper(II)-chloride complex.
Topics: Chlorides; Copper; Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Structure; Oxazoles; Stereoisomerism; Urea | 2009 |
Recoveries of trace pseudoephedrine and methamphetamine residues from impermeable household surfaces: implications for sampling methods used during remediation of clandestine methamphetamine laboratories.
Topics: Environmental Restoration and Remediation; Housing; Laboratories; Methamphetamine; Oxazoles; Permeability; Pseudoephedrine; Surface Properties | 2010 |
Highly diastereoselective alpha-hydroxylation of Fox chiral auxiliary-based amide enolates with molecular oxygen.
Topics: Alcohols; Amides; Carboxylic Acids; Hydroxylation; Ketones; Molecular Conformation; Oxazoles; Oxygen; Stereoisomerism | 2010 |
Stability studies of oxazolidine-based compounds using 1H NMR spectroscopy.
Topics: Deuterium Oxide; Hydrolysis; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Oxazoles; Prodrugs; Reproducibility of Results; Structure-Activity Relationship | 2010 |
Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Azepines; Drug Resistance, Bacterial; Lipids; Nucleosides; Oxazoles; Uridine | 2010 |
Synthesis of 2-trifluoromethyl-1,3-oxazolidines as hydrolytically stable pseudoprolines.
Topics: Acylation; Esters; Fluorine; Methane; Molecular Structure; Oxazoles; Proline; Thiazoles | 2010 |
A novel chiral oxazolidine organocatalyst for the synthesis of an oseltamivir intermediate using a highly enantioselective Diels-Alder reaction of 1,2-dihydropyridine.
Topics: Antiviral Agents; Catalysis; Dihydropyridines; Oseltamivir; Oxazoles; Quinuclidines; Stereoisomerism | 2010 |
Boron-based dipolar multicomponent reactions: simple generation of substituted aziridines, oxazolidines and pyrrolidines.
Topics: Aziridines; Catalysis; Combinatorial Chemistry Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Oxazoles; Pyrrolidines | 2010 |
A direct synthesis of oxazoles from aldehydes.
Topics: Aldehydes; Catalysis; Combinatorial Chemistry Techniques; Molecular Structure; Oxazoles | 2010 |
Straightforward synthesis of enantiopure (R)- and (S)-trifluoroalaninol.
Topics: Oxazoles; Propanolamines; Pyruvic Acid; Stereoisomerism | 2010 |
Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives.
Topics: Antitubercular Agents; Crystallography, X-Ray; Drug Design; Mefloquine; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Oxazoles; Structure-Activity Relationship | 2010 |
Diastereoselective access to trans-2-substituted cyclopentylamines.
Topics: Amines; Anilides; Cyclization; Cyclopentanes; Lewis Acids; Molecular Structure; Oxazoles; Stereoisomerism | 2010 |
Novel 9a,11-bridged azalides: One-pot synthesis of N'-substituted 2-imino-1,3-oxazolidines condensed to an azalide aglycone.
Topics: Aza Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Oxazoles; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared | 2011 |
Diastereo- and enantioselective synthesis of oxazine and oxazolidine derivatives with a chiral quaternary carbon center under multifunctional catalysis.
Topics: Combinatorial Chemistry Techniques; Molecular Structure; Oxazines; Oxazoles; Stereoisomerism | 2011 |
2,2-Difunctionalization of alkenes via Pd(II)-catalyzed aza-Wacker reactions.
Topics: Alkenes; Catalysis; Cyclization; Imidazolidines; Molecular Structure; Oxazoles; Palladium; Stereoisomerism | 2011 |
Synthesis and in vitro antibacterial activity of oxazolidine LBM-415 analogs as peptide deformylase inhibitors.
Topics: Amidohydrolases; Anti-Bacterial Agents; Drug Design; Humans; Microbial Sensitivity Tests; Molecular Structure; Oxazoles; Peptides | 2011 |
Unusual transglycosylation activity of Flavobacterium meningosepticum endoglycosidases enables convergent chemoenzymatic synthesis of core fucosylated complex N-glycopeptides.
Topics: Chryseobacterium; Fucose; Glycoproteins; Glycoside Hydrolases; Glycosylation; Oxazoles | 2011 |
Importance of porins for biocide efficacy against Mycobacterium smegmatis.
Topics: Biguanides; Disinfectants; Gene Deletion; Imines; Microbial Viability; Mycobacterium smegmatis; Oxazines; Oxazoles; Porins; Pyridines; Staining and Labeling; Thiazoles; Triazines; Xanthenes | 2011 |
A synthetic route to highly substituted 1,2,3,4-tetrahydroisoquinolines via Yb(OTf)3 -catalyzed diastereoselective ring opening of bridged oxazolidines: asymmetric synthesis of 2-azapodophyllotoxin.
Topics: Bridged-Ring Compounds; Catalysis; Lewis Acids; Molecular Structure; Oxazoles; Podophyllotoxin; Stereoisomerism; Tetrahydroisoquinolines; Ytterbium | 2011 |
A quantitative structure-reactivity relationship in N-acetyl oxazolidines: an electrostatic interaction controls rotamer population.
Topics: Acetylation; Hydrogen Bonding; Models, Molecular; Molecular Structure; Oxazoles; Static Electricity; Stereoisomerism; Structure-Activity Relationship | 2011 |
Nitrogen dynamics and reactivity of chiral aziridines: generation of configurationally stable aziridinyllithium compounds.
Topics: Aziridines; Lithium; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nitrogen; Organometallic Compounds; Oxazoles; Stereoisomerism | 2011 |
Enhancement of chromium uptake in tanning using oxazolidine.
Topics: Chromium; Industrial Waste; Oxazoles; Tanning; Water Pollutants, Chemical | 2011 |
Diversity-oriented synthesis based on the DPPP-catalyzed mixed double-Michael reactions of electron-deficient acetylenes and β-amino alcohols.
Topics: Alkynes; Amino Alcohols; Catalysis; Molecular Structure; Oxazoles; Phosphines; Propane | 2011 |
Synthesis and ring-chain-ring tautomerism of bisoxazolidines, thiazolidinyloxazolidines, and spirothiazolidines.
Topics: Kinetics; Molecular Conformation; Oxazoles; Stereoisomerism; Thermodynamics | 2011 |
Design, syntheses, and kinetic evaluation of 3-(phenylamino)oxazolidine-2,4-diones as potent cytochrome bc₁ complex inhibitors.
Topics: Animals; Drug Design; Electron Transport Complex III; Enzyme Inhibitors; Oxazoles; Succinate Cytochrome c Oxidoreductase; Swine | 2011 |
Synthesis, characterization, and antihyperglycemic activity of novel oxazolidine derivatives.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Oxazoles; Rats; Rats, Sprague-Dawley; Spectrum Analysis; Streptozocin; Sucrose | 2011 |
Stereoselective synthesis of substituted 1,3-oxazolidines via Pd-catalyzed carboamination reactions of O-vinyl-1,2-amino alcohols.
Topics: Amination; Amino Alcohols; Catalysis; Molecular Structure; Organometallic Compounds; Oxazoles; Palladium; Stereoisomerism | 2011 |
Oxazolidine synthesis by complementary stereospecific and stereoconvergent methods.
Topics: Catalysis; Kinetics; Molecular Structure; Oxazoles; Stereoisomerism | 2011 |
Asymmetric synthesis of chiral 1,3-diaminopropanols: bisoxazolidine-catalyzed C-C bond formation with α-keto amides.
Topics: Amides; Catalysis; Molecular Structure; Oxazoles; Propanolamines; Propanols; Stereoisomerism | 2011 |
Mefloquine-oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113.
Topics: Aldehydes; Animals; Antitubercular Agents; Cells, Cultured; Drug Resistance, Multiple, Bacterial; Ethambutol; Mefloquine; Mice; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Oxazoles | 2012 |
Highly diastereoselective synthesis of enantiopure β-trifluoromethyl β-amino alcohols from chiral trifluoromethyl oxazolidines (Fox).
Topics: Amino Alcohols; Fluorine Compounds; Imines; Methylation; Molecular Structure; Oxazoles; Stereoisomerism | 2012 |
A simple oxazolidine linker for solid-phase synthesis of peptide aldehydes.
Topics: Aldehydes; Chromatography, High Pressure Liquid; Molecular Structure; Oxazoles; Peptides; Spectrometry, Mass, Electrospray Ionization | 2012 |
Highly efficient and stereoselective construction of dispiro-[oxazolidine-2-thione]bisoxindoles and dispiro[imidazolidine-2-thione]bisoxindoles.
Topics: Indoles; Molecular Structure; Oxazoles; Oxindoles; Spiro Compounds; Stereoisomerism | 2012 |
Remote stereocontrol in [3,3]-sigmatropic rearrangements: application to the total synthesis of the immunosuppressant mycestericin G.
Topics: Amino Acids; Fatty Acids, Unsaturated; Immunosuppressive Agents; Models, Molecular; Molecular Structure; Oxazoles; Stereoisomerism | 2012 |
Water-developable poly(2-oxazoline)-based negative photoresists.
Topics: Molecular Structure; Oxazoles; Photochemistry; Polymers; Ultraviolet Rays | 2012 |
Naturally occurring norephedrine oxazolidine derivatives in khat (Catha edulis).
Topics: Catha; Ephedrine; Oxazoles; Plants, Medicinal | 2012 |
Partial conversion of methanol to formaldehyde in the gas chromatography injection port and reactivity with amines.
Topics: Amines; Cyclobutanes; Ephedrine; Formaldehyde; Gas Chromatography-Mass Spectrometry; Imines; Methanol; Oxazoles; Phenylpropanolamine; Solvents; Temperature | 2012 |
N-(Diazoacetyl)oxazolidin-2-thiones as sulfur-donor reagents: asymmetric synthesis of thiiranes from aldehydes.
Topics: Aldehydes; Cycloaddition Reaction; Oxazoles; Stereoisomerism; Sulfides; Sulfur; Thiones | 2012 |
Chiral bicyclic tetramates as non-planar templates for chemical library synthesis.
Topics: Anti-Bacterial Agents; Escherichia coli; Oxazoles; Staphylococcus aureus; Thiazolidines | 2013 |
Synthesis, biological evaluation of new oxazolidino-sulfonamides as potential antimicrobial agents.
Topics: Anti-Bacterial Agents; Antifungal Agents; Dose-Response Relationship, Drug; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Conformation; Oxazoles; Structure-Activity Relationship; Sulfonamides | 2013 |
Dual behavior of isatin-based cyclic ketimines with dicarbomethoxy carbene: expedient synthesis of highly functionalized spirooxindolyl oxazolidines and pyrrolines.
Topics: Azo Compounds; Crystallography, X-Ray; Cycloaddition Reaction; Imines; Indoles; Isatin; Molecular Structure; Nitriles; Oxazoles; Pyrroles; Spiro Compounds; Stereoisomerism; Thiosemicarbazones | 2013 |
Crystallization-induced dynamic resolution of Fox chiral auxiliary and application to the diastereoselective electrophilic fluorination of amide enolates.
Topics: Amides; Crystallization; Molecular Structure; Oxazoles; Stereoisomerism; Thermodynamics | 2013 |
Metabolism of a serotonin-4 receptor partial agonist 4-{4-[4-tetrahydrofuran-3-yloxy)-benzo[d]isoxazol-3-yloxymethyl]-piperidin-1-ylmethyl}-tetrahydropyran-4-ol (TBPT): identification of an unusual pharmacologically active cyclized oxazolidine metabolite
Topics: Animals; Blood Proteins; Brain; Cyclization; Dealkylation; Dogs; Female; Furans; Hepatocytes; Humans; Hydroxylation; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists | 2013 |
Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.
Topics: Animals; Binding Sites; Drug Evaluation, Preclinical; Half-Life; Humans; Microsomes; Mineralocorticoid Receptor Antagonists; Molecular Docking Simulation; Oxazoles; Protein Structure, Tertiary; Rats; Receptors, Mineralocorticoid; Structure-Activity Relationship | 2013 |
Palladium(II)-catalyzed enantioselective synthesis of α-(trifluoromethyl)arylmethylamines.
Topics: Catalysis; Ligands; Methylamines; Molecular Structure; Oxazoles; Palladium; Pyridines; Stereoisomerism | 2013 |
Development of a tailor-made bis(oxazolidine)pyridine-metal catalyst for the [3+2] cycloaddition of azomethine imines with propiolates.
Topics: Alkynes; Azo Compounds; Catalysis; Cycloaddition Reaction; Imines; Ligands; Metals; Oxazoles; Propionates; Pyridines; Stereoisomerism; Thiosemicarbazones | 2013 |
Mefloquine-oxazolidine derivatives: a new class of anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Cell Survival; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Humans; Mefloquine; Molecular Conformation; Oxazoles; Quinolines; Stereoisomerism; Structure-Activity Relationship | 2014 |
Mechanistic insight into the spirocyclopropane isoxazolidine ring contraction.
Topics: beta-Lactams; Catalysis; Cyclopropanes; Molecular Structure; Oxazoles; Quantum Theory; Spiro Compounds | 2014 |
A quantitative structure-activity relationship (QSAR) study on a few series of potent, highly selective inhibitors of nitric oxide synthase.
Topics: Enzyme Inhibitors; Nitric Oxide Synthase Type II; Oxazoles; Quantitative Structure-Activity Relationship; Thiazolidines | 2014 |
Asymmetric one-pot synthesis of 1,3-oxazolidines and 1,3-oxazinanes via hemiaminal intermediates.
Topics: Alcohols; Catalysis; Cyclization; Imines; Molecular Structure; Oxazines; Oxazoles; Stereoisomerism | 2014 |
Catalytic asymmetric synthesis of the pentacyclic core of (-)-nakadomarin A via oxazolidine as an iminium cation equivalent.
Topics: Carbolines; Catalysis; Cations; Imines; Molecular Conformation; Organometallic Compounds; Oxazoles; Palladium; Stereoisomerism | 2014 |
Low-temperature molecular motions in lipid bilayers in the presence of sugars: insights into cryoprotective mechanisms.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Carbohydrates; Cold Temperature; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Movement; Oxazoles; Spin Labels | 2014 |
Glucosinolate hydrolysis products in the crucifer Barbarea vulgaris include a thiazolidine-2-one from a specific phenolic isomer as well as oxazolidine-2-thiones.
Topics: Barbarea; Catalysis; Glucosinolates; Hydrolysis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxazoles; Plant Leaves; Stereoisomerism; Thiazolidines; Thiones | 2015 |
Straightforward synthesis of novel enantiopure α-trifluoromethylated azetidine 2-carboxylic acid and homoserines.
Topics: Acetoacetates; Amino Alcohols; Azetidinecarboxylic Acid; Azetidines; Catalysis; Homoserine; Molecular Structure; Oxazoles; Stereoisomerism | 2015 |
Synthesis of unusual N-acylated aminosugar fragments of Mycobacterium marinum lipooligosaccharide IV.
Topics: Acylation; Amino Acids; Amino Sugars; Cyclization; Lipopolysaccharides; Mycobacterium marinum; Oxazoles; Oxidation-Reduction | 2015 |
Synthesis of enantiopure trans-2,5-disubstituted trifluoromethylpyrrolidines and (2S,5R)-5-trifluoromethylproline.
Topics: Hydrocarbons, Fluorinated; Indicators and Reagents; Molecular Structure; Oxazoles; Proline; Pyrrolidines; Stereoisomerism | 2015 |
Effects of singlet oxygen generated by a broad-spectrum viral fusion inhibitor on membrane nanoarchitecture.
Topics: Antiviral Agents; Cell Membrane; Membrane Lipids; Microscopy, Atomic Force; Models, Molecular; Oxazoles; Phospholipids; Singlet Oxygen; Thiones; Virus Internalization | 2015 |
Design, synthesis and structure-activity relationship of oxazolidinone derivatives containing novel S4 ligand as FXa inhibitors.
Topics: Animals; Anticoagulants; Blood Coagulation; Dose-Response Relationship, Drug; Drug Design; Factor Xa; Factor Xa Inhibitors; Humans; Ligands; Molecular Structure; Oxazoles; Rabbits; Structure-Activity Relationship | 2015 |
Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3).
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; DNA Gyrase; Escherichia coli; Microbial Sensitivity Tests; Naphthyridines; Oxazoles; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase Inhibitors | 2015 |
Weak C-H···O and C-H···π hydrogen bonds and π-π stacking interactions in a series of four N'-[(E)-(aryl)methylidene]-N-methyl-2-oxo-1,3-oxazolidine-4-carbohydrazides.
Topics: Benzylidene Compounds; Crystallography, X-Ray; Hydrazines; Hydrogen Bonding; Molecular Structure; Oxazoles | 2015 |
Correlation of in Situ Oxazolidine Formation with Highly Synergistic Cytotoxicity and DNA Cross-Linking in Cancer Cells from Combinations of Doxorubicin and Formaldehyde.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cross-Linking Reagents; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Esterases; Formaldehyde; Humans; Liver; Molecular Structure; Oxazoles; Prodrugs; Structure-Activity Relationship; Swine; Tumor Cells, Cultured | 2016 |
Function-Oriented Synthesis: How to Design Simplified Analogues of Antibacterial Nucleoside Natural Products?
Topics: Anti-Bacterial Agents; Biological Products; Drug Design; Enterococcus; Isoxazoles; Microbial Sensitivity Tests; Nucleosides; Oxazoles; Staphylococcus aureus; Structure-Activity Relationship | 2016 |
Batch- and Continuous-Flow Aerobic Oxidation of 14-Hydroxy Opioids to 1,3-Oxazolidines-A Concise Synthesis of Noroxymorphone.
Topics: Catalysis; Colloids; Hydrogenation; Morphinans; Oxazoles; Oxidants; Oxidation-Reduction; Oxygen; Palladium; Surface Properties | 2016 |
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection.
Topics: Animals; Antitubercular Agents; Bacterial Load; Disease Models, Animal; Drug Interactions; Drug Repositioning; Male; Mefloquine; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Design, synthesis and structure-activity relationship studies of a novel focused library of 2,3,4-substituted oxazolidines with antiproliferative activity against cancer cell lines.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oxazoles; Structure-Activity Relationship; Vero Cells | 2017 |
Protein Interactions with Nanoengineered Polyoxazoline Surfaces Generated via Plasma Deposition.
Topics: Adsorption; Animals; Fibrinogen; Gold; Metal Nanoparticles; Nanostructures; Oxazoles; Serum Albumin, Bovine; Surface Properties | 2017 |
Two goitrogenic 1,3-oxazolidine-2-thione derivatives from Brassicales taxa: Challenging identification, occurrence and immunomodulatory effects.
Topics: Animals; Brassicaceae; Chromatography, Gas; Humans; Immunologic Factors; Inflammation; Magnetic Resonance Spectroscopy; Molecular Structure; Oxazoles; Plant Extracts; Rats; Rats, Wistar; Stereoisomerism; Thiones | 2017 |
Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio.
Topics: Adult; Cyclization; Dealkylation; Female; Furans; Hepatocytes; Humans; Inactivation, Metabolic; Kinetics; Male; Middle Aged; Models, Biological; Oxazoles; Serotonin Receptor Agonists; Young Adult | 2018 |
Asymmetric synthesis, molecular modeling and biological evaluation of 5-methyl-3-aryloxazolidine-2,4-dione enantiomers as monoamine oxidase (MAO) inhibitors.
Topics: Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Kinetics; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Stereoisomerism; Structure-Activity Relationship | 2018 |
A Zero Cross-Talk Ratiometric Two-Photon Probe for Imaging of Acid pH in Living Cells and Tissues and Early Detection of Tumor in Mouse Model.
Topics: Acids; Animals; Carbazoles; Early Detection of Cancer; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Oxazoles; Photons | 2018 |
Synthesis, Spectroscopic Characterization, and
Topics: Anti-Bacterial Agents; Bacteria; Humans; Microbial Sensitivity Tests; Organophosphonates; Oxazoles; Pharmaceutical Preparations | 2018 |
Pre-clinical pharmacodynamic study of a novel oral factor Xa inhibitor zifaxaban.
Topics: Administration, Oral; Animals; Blood Coagulation; Factor Xa Inhibitors; Female; Male; Oxazoles; Platelet Aggregation; Rats; Rats, Wistar; Venous Thrombosis | 2018 |
Thermodynamic Characterization of Mixed Monolayers of a Novel Oxazolidine Derivative and Phospholipids.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Microscopy, Atomic Force; Oxazoles; Phosphatidylglycerols; Phospholipids; Phosphorylcholine; Thermodynamics | 2018 |
4-Iminooxazolidin-2-one as a Bioisostere of the Cyanohydrin Moiety: Inhibitors of Enterovirus 71 3C Protease.
Topics: 3C Viral Proteases; Animals; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enterovirus A, Human; Male; Mice; Molecular Docking Simulation; Nitriles; Oxazoles; Protein Conformation; Viral Proteins | 2018 |
Structures and Reactivities of Sodiated Evans Enolates: Role of Solvation and Mixed Aggregation on the Stereochemistry and Mechanism of Alkylations.
Topics: Alkenes; Alkylation; Kinetics; Models, Molecular; Molecular Conformation; Oxazoles; Solvents; Stereoisomerism | 2019 |
Residues and dissipation kinetics of famoxadone and its metabolites in environmental water and soil samples under different conditions.
Topics: Chromatography, High Pressure Liquid; Fungicides, Industrial; Half-Life; Kinetics; Mass Spectrometry; Oxazoles; Pesticide Residues; Propionates; Soil; Soil Pollutants; Strobilurins; Water | 2019 |
Protective Responses Induced by Chiral 3-Dichloroacetyl Oxazolidine Safeners in Maize (
Topics: Acetolactate Synthase; Binding Sites; Catalase; Catalytic Domain; Glutathione; Inactivation, Metabolic; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Oxazoles; Peroxidase; Protective Agents; Protein Binding; Structure-Activity Relationship; Zea mays | 2019 |
[Overview of 43 Years of Studies on Asymmetric Synthesis].
Topics: Chemistry, Organic; Fluorine Compounds; Imines; Organometallic Compounds; Oxazoles; Stereoisomerism; Time Factors | 2020 |
Visible-Light-Induced Charge Transfer Enables C
Topics: Cycloaddition Reaction; Epoxy Compounds; Glycine; Light; Molecular Structure; Oxazoles; Oxidation-Reduction | 2020 |
Construction of 1,3-Oxazolidines through a Three-Component [3+2] Cycloaddition of Tetrahydroisoquinolines, Aldehydes, and Ethyl Ketomalonate.
Topics: Aldehydes; Amines; Cyclization; Cycloaddition Reaction; Malonates; Oxazoles; Stereoisomerism; Tetrahydroisoquinolines | 2020 |
Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize.
Topics: Herbicides; Oxazoles; Pyridines; Sulfonylurea Compounds; Zea mays | 2021 |
New Oxazolidines Inhibit the Secretion of IFN-γ and IL-17 by PBMCS from Moderate to Severe Asthmatic Patients.
Topics: Asthma; Dose-Response Relationship, Drug; Drug Design; Humans; Interferon-gamma; Interleukin-17; Leukocytes, Mononuclear; Molecular Docking Simulation; Oxazoles; Protein Conformation; Receptors, Neurokinin-1 | 2021 |
A near-infrared fluorescent probe based on a hemicyanine dye with an oxazolidine switch for mitochondrial pH detection.
Topics: Carbocyanines; Cell Survival; Density Functional Theory; Dose-Response Relationship, Drug; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mitochondria; Molecular Structure; Oxazoles; Particle Size; Spectrometry, Fluorescence; Surface Properties | 2021 |
Investigation of a new oxazolidine derivative in human resistance acute leukemia cells: deciphering its mechanism of action by label-free proteomic.
Topics: Antineoplastic Agents; Cell Cycle; Cytokines; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Oxazoles; Proteomics; Signal Transduction | 2021 |
Expanding the Scope of the Cleavable
Topics: Aldehydes; Hydrazones; Molecular Structure; Oligonucleotides; Oxazoles; Peptide Nucleic Acids | 2021 |
Formation of Oxazolidine Derivatives by Reaction with Ephedrines and Aldehyde Impurities in Ethyl Acetate.
Topics: Acetaldehyde; Acetates; Aldehydes; Ephedrine; Formaldehyde; Oxazoles | 2022 |
Organocatalytic Asymmetric Synthesis of Spirooxindole Embedded Oxazolidines.
Topics: Catalysis; Isatin; Oxazoles; Stereoisomerism | 2021 |
Asymmetric 1,2-Carbamoyl Rearrangement of Lithiated Chiral Oxazolidine Carbamates and Diastereoselective Synthesis of α-Hydroxy Amides.
Topics: Acids; Amides; Carbamates; Molecular Structure; Oxazoles; Stereoisomerism | 2022 |
Divergent synthesis of biologically active L-threo-β-hydroxyaspartates from common trans-oxazolidine dicarboxylate.
Topics: Amino Acids; Carboxylic Acids; Dipeptides; Oxazoles | 2022 |
Copper-catalyzed
Topics: Catalysis; Copper; Iodides; Molecular Structure; Oxazoles; Thiones | 2022 |
Rational Design of Oxazolidine-Based Red Fluorescent pH Probe for Simultaneous Imaging Two Subcellular Organelles.
Topics: Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Organelles; Oxazoles | 2022 |
Schiff Bases and Stereocontrolled Formation of Fused 1,3-Oxazolidines from 1-Amino-2-Indanol: A Systematic Study on Structure and Mechanism.
Topics: Imines; Oxazoles; Schiff Bases | 2023 |
Synthesis of fused tetramate-oxazolidine and -imidazolidine derivatives and their antibacterial activity.
Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Imidazolidines; Oxazoles | 2023 |