oxazoles has been researched along with oxazolidin-2-one in 412 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 106 (25.73) | 18.7374 |
| 1990's | 196 (47.57) | 18.2507 |
| 2000's | 65 (15.78) | 29.6817 |
| 2010's | 36 (8.74) | 24.3611 |
| 2020's | 9 (2.18) | 2.80 |
| Authors | Studies |
|---|---|
| Benedetti, MS; Kan, JP; Malone, A | 1 |
| Sato, M; Stammer, CH | 1 |
| Benedetti, MS; Kan, JP; Keane, PE; Sontag, N | 1 |
| Curtis, DR; Hjeds, H; Johnston, GA; Krogsgaard-Larsen, P; Lodge, D | 1 |
| Akerström, L; Josefsson, E | 1 |
| Coston, A; Gouret, C; Raynaud, G | 1 |
| Lang, R | 1 |
| Dent, RW; Ervin, DK | 1 |
| Gorecki, DK; Peesker, SJ; Wood, JD | 1 |
| Bleyl, DW; Lewerenz, HJ; Schnaak, W | 1 |
| Baker, WR; Boyd, SA; Cohen, J; Condon, SL; Dayton, BD; Donner, BG; Fung, AK; Luly, JR; Rosenberg, SH; Stein, HH | 1 |
| Lamiable, D; Leon, A; Vistelle, R; Wiczewski, M; Zinsou, M | 1 |
| Cayre, I; Gonzalez-Jimenez, J; Jacquotte, H | 1 |
| D'Estanque, J; Ego, D; Funck-Brentano, C; Jaillon, P; Provost, JC; Rovei, V | 1 |
| Kukkola, PJ; Marsh, RE; Myers, AG; Schaefer, WP | 1 |
| Lemoine, P; Mirabaud, C | 1 |
| Berlin, I; Dingemanse, J; Payan, C; Puech, AJ; Thiede, HM | 1 |
| Berlin, I; Hergueta, T; Payan, C; Puech, AJ; Robin, L; Thiede, HM; Zimmer, R | 1 |
| Paik, IK | 1 |
| Bargnoux, H; Bastide, M; Berger, JA; Buch, N; Chabard, JL; Lartigue, C; Lesieur, D; Mansour, HA; Petit, J | 1 |
| Alvarez, M; Caetano Esquivel, G; Fernández Labriola, R; Servidio, M | 1 |
| Foxwell, MH; Johnson, DN; Kilpatrick, BF; Nolan, JC; Proakis, AG; Walsh, DA; Whitman, LL; Yanni, JM | 1 |
| Stier, MA; Suto, MJ; Werbel, LM | 1 |
| Kamal, A; Rao, AB; Rao, MV | 1 |
| Hoogenboom, LA; Kuiper, HA; Oorsprong, MB; Tomassini, O | 1 |
| Swango, LJ; Williams, DE; Wilt, GR; Worley, SD | 1 |
| Berghmans, MC; Hoogenboom, LA; Koeman, JH; Kuiper, HA; van Kammen, M | 1 |
| Kuschinsky, K; Welsch-Kunze, S | 1 |
| Kadam, JR; Kleinert, HD; Rosenberg, SH; Verburg, KM; Young, GA | 1 |
| Bogaards, JJ; Falke, HE; van Bladeren, PJ; van Ommen, B; Willems, MI | 1 |
| Babany, G; Benhamou, JP; Degott, C; Delafosse, B; Hadengue, A; Larrey, D; Pateron, D; Sylvain, C | 1 |
| Garrick, NA; Linnoila, M; Murphy, DL; Seppala, T | 1 |
| Bachmann, M; Lüthy, J; Schlatter, C; Theus, R | 1 |
| Fenwick, GR; McMillan, M; Spinks, EA | 1 |
| Eustice, DC; Feldman, PA; Slee, AM | 1 |
| Izumiyama, K; Kogure, K | 1 |
| Eustice, DC; Feldman, PA; Slee, AM; Zajac, I | 1 |
| Fletcher, PJ; Yu, PH | 1 |
| Mazzei, T; Mini, E; Novelli, A; Periti, P | 1 |
| Brumfitt, W; Hamilton-Miller, JM; Maple, PA | 1 |
| Da Prada, M; Keller, HH; Kettler, R | 1 |
| Bleyl, DW; Lewerenz, HJ; Plass, R; Przybilski, H; Schnaak, W | 1 |
| Goto, Y; Ishida, M; Shinozaki, H | 1 |
| Lamiable, D; Vistelle, R; Zinzou, M | 1 |
| Brumfitt, W; Gargan, RA; Hamilton-Miller, JM | 1 |
| Kimura, A; Sato, A; Suzuki, A; Suzuki, H | 1 |
| Masaki, M; Shinozaki, H | 1 |
| Chambrade, S; Dallel, R; Rajaona, J; Woda, A | 1 |
| Chekroun, I; Krstulović, AM; Long, D; Porziemsky, JP; Rossey, G | 1 |
| Shinozaki, H | 1 |
| Ahmed, H; Aull, JL; Williams, DE; Worley, SD | 1 |
| Callingham, BA | 1 |
| Bizière, K; Kan, JP; Mouget-Goniot, C; Steinberg, R; Worms, P | 1 |
| Bjeldanes, LF; Chang, Y | 2 |
| Dostert, P; Strolin Benedetti, M | 1 |
| Jarrott, B; Vajda, FJ | 1 |
| Brumfitt, W; Hamilton-Miller, JM | 1 |
| Greenshaw, AJ; Turkish, S; Yu, PH | 1 |
| Finberg, JP; Youdim, MB | 1 |
| Blagburn, BL; Hendrix, CM; Kong, LI; Swango, LJ; Williams, DE; Worley, SD | 1 |
| Elder, ED; Williams, DE; Worley, SD | 2 |
| Konno, F; Sato, Y; Takayanagi, I; Uno, H | 1 |
| Barry, AL | 1 |
| Chin, NX; Neu, HC; Novelli, A; Saha, G | 1 |
| Daly, JS; Eliopoulos, GM; Moellering, RC; Reiszner, E | 1 |
| Bartholomew, PT; Forbes, M; Gregory, WA; McRipley, RJ; Slee, AM; Wuonola, MA; Zajac, I; Zawada, MJ | 1 |
| Killen, AD; Swango, LJ; Williams, DE; Wilt, GR; Worley, SD | 1 |
| Peutillot, A; Servant, D | 1 |
| Arai, Y; Kinemuchi, H; Morikawa, F; Ueda, T | 1 |
| Fuller, RW; Hemrick-Luecke, SK | 1 |
| Swango, LJ; Wheatley, WB; Williams, DE; Worley, SD | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Wong, CJ | 1 |
| Pourrat, A; Schiff, V; Si-Nang, L; Simond, J; Trottier, D | 1 |
| Waldmeier, PC | 1 |
| Janda, J | 1 |
| Fuller, RW; Roush, BW | 1 |
| Földes, O; Gschwendtová, K; Langer, P | 1 |
| Dostert, P; Sontag, N; Strolin Benedetti, M | 1 |
| Bucher, B; Coston, A; Jalfre, M; Mocquet, G; Porsolt, RD | 1 |
| Dostert, P; Guffroy, C; Strolin Benedetti, M | 1 |
| Dow, J; Strolin Benedetti, M | 1 |
| Boucher, T; Dostert, P; Dow, J; Strolin Benedetti, M | 1 |
| Boucher, T; Dostert, P; Guffroy, C; Strolin Benedetti, M | 1 |
| Elfving, S | 1 |
| Fenwick, GR; Griffiths, NM | 1 |
| Daxenbichler, E; Nishie, K | 1 |
| Chanoine, F; Rovei, V; Strolin Benedetti, M; Tillement, JP; Zini, R | 1 |
| Butler, EJ; Fenwick, GR; Greenwood, NM; Pearson, AW | 1 |
| Deniker, P; Lesage, A; Lôo, H; Olié, JP; Poirier, MF; Rovei, V; Strolin Benedetti, M | 1 |
| Boucher, T; Fowler, CJ; Henehan, GT; McCrodden, JM; Tipton, KF | 1 |
| Benedetti, MS; Fowler, CJ | 1 |
| Benedetti, MS; Dostert, P; Guffroy, C; Tipton, KF | 1 |
| Diakov, L; Dimitrov, Kh | 1 |
| Brown, MJ; Causon, RC | 1 |
| Busch, N; Chastaing, G; Chatonier, D; Luu, SN; Pourrat, A; Trottier, D | 1 |
| Le Moing, JP; Rovei, V; Vajta, S | 2 |
| Dordain, G; Dostert, P; Eschalier, A; Lesage, A; Rovei, V; Strolin Benedetti, M; Zarifian, E | 1 |
| Brown, MJ; Davies, DS; Dollery, CT; Lewis, PJ; Strolin-Benedetti, M | 1 |
| Boucher, T; Fowler, CJ; Strolin Benedetti, M | 1 |
| Rigal, M; Rovei, V; Sanjuan, M; Thiola, A | 1 |
| Kendall, MJ; Mitchard, M; Rovei, V; Strolin Benedetti, M | 1 |
| Bachmann, M; Carden, B; Friederich, U; Lüthy, J | 1 |
| Ancher, JF; Benedetti, MS; Sontag, N | 1 |
| Bodor, N; Burkett, HD; Faison, JH; Kohl, HH; Mora, EC; Wheatley, WB; Worley, SD | 1 |
| Fowler, CJ; Strolin Benedetti, M | 1 |
| Benedetti, MS; Boucher, T; Carlsson, A; Fowler, CJ | 1 |
| Fowler, CJ; McCrodden, JM; Strolin Benedetti, M; Tipton, KF | 1 |
| Da Prada, M; Haefely, WE; Keller, HH; Kettler, R | 1 |
| Ballester, D; Brunser, O; King, J; Vera, P; Yánez, E | 1 |
| de Brabander, HF; Verbeke, R | 1 |
| Benedetti, MS; Dencker, SJ; Johansson, R; Nagy, A; Rovei, V | 1 |
| Kan, JP; Strolin Benedetti, M | 1 |
| Benedetti, MS; Kan, JP | 1 |
| Maskell, I; Smithard, R | 1 |
| Bjeldanes, LF; Kelley, MK | 1 |
| Blake, P; de Bruijn, EA; Harper, PG; Highley, MS; Maes, RA; Mansi, J; Momerency, G; Van Cauwenberghe, K; Van Oosterom, AT | 1 |
| Lewerenz, HJ; Ozierenski, B; Plass, R | 1 |
| Gimbrett, R; Priest, RG; Roberts, M; Steinert, J | 1 |
| Fujii, S; Hayashi, K; Ikeda, K; Inoue, S; Iwama, S; Katsumura, S; Matsuda, T; Samejima, Y; Tani, T | 1 |
| Akasaka, K; Horie, T; Kagaya, T; Kubota, A; Nagato, S; Naitoh, T | 1 |
| Arancio, C; Bellodi, L; Bertani, A; Cocchi, S; Perna, G | 1 |
| Garner, CW; Smith, LK; Turnbow, MA | 1 |
| Lefebvre, H; Moore, N; Noblet, C; Richard, R; Wolf, LM | 1 |
| De Bruijn, EA; Momerency, G; Slee, PH; Van Cauwenberghe, K; Van Oosterom, AT | 1 |
| Ding, CZ; Silverman, RB | 1 |
| Crain, GM; Gelber, DA; Jung, S; Markwell, SJ; Pfeifer, MA; Ross, DR; Schrage, JP; Schumer, MP | 1 |
| Good, LA; Hua, DH; Meyers, CY; Robinson, PD; Wang, H | 1 |
| Bertschy, G; Bouquet, S; Chakroun, R; Guibert, S; Perault, MC; Sandoz, M; Vandel, B; Vandel, S | 1 |
| Fujii, S; Ikeda, K; Iwama, S; Katsumura, S; Matsuda, T; Takehara, H; Tani, T | 1 |
| Iseki, K; Kobayashi, Y; Namba, H; Oishi, S; Taguchi, T | 1 |
| Barbachyn, MR; Brickner, SJ; Ford, CW; Garmon, SA; Grega, KC; Hendges, SK; Hutchinson, DK; Manninen, PR; Toops, DS; Ulanowicz, DA; Zurenko, GE | 1 |
| Freund, P; Heitzmann, T; Neidlein, R; Reiff, K; Strein, K | 1 |
| Cox, RC; Ferrari, MD; Jones, D; Klein, KB; Visser, WH | 1 |
| Barbachyn, MR; Brickner, SJ; Ford, CW; Hamel, JC; Hutchinson, DK; Moerman, JK; Stapert, D; Wilson, DM; Yancey, RJ | 1 |
| Akasaka, K; Kagaya, T; Kajiwara, A; Kubota, A; Nagato, S | 1 |
| Ferrari, MD | 3 |
| Earl, NL | 1 |
| Martin, GR | 2 |
| Geraud, GE | 1 |
| Dowson, A | 2 |
| Edmeads, JG | 1 |
| Bendtsen, L; Daugaard, D; Dixon, R; Gibbens, M; Langemark, M; Lassen, LH; Olesen, J; Thomsen, LL | 1 |
| Eliopoulos, GM; Gold, HS; Moellering, RC; Wennersten, CB | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 1 |
| Churchus, R; On, N; Phillips, S; Posner, J; Rolan, P; Seaber, E | 1 |
| Kaplan, SL; Lamberth, LB; Mason, EO | 1 |
| Allison, JW; Barbachyn, MR; Brickner, SJ; Glickman, SE; Hutchinson, DK; Kilburn, JO; Schaadt, RD; Yagi, BH; Zurenko, GE | 1 |
| Guba, W; Islam, K; Ranaldi, G; Sambuy, Y; Seneci, P | 1 |
| Erwin, ME; Johnson, DM; Jones, RN | 1 |
| Kaatz, GW; Seo, SM | 1 |
| Drenning, SD; Mulazimoglu, L; Yu, VL | 1 |
| Goadsby, PJ; Hoskin, KL | 2 |
| Jorgensen, JH; McElmeel, ML; Trippy, CW | 1 |
| Goadsby, PJ; Olesen, J | 1 |
| Zagami, AS | 1 |
| Dowson, AJ | 1 |
| Dixon, R; Gibbens, M; Gillotin, C; Peck, RW; Posner, J | 1 |
| Kennedy, DG; McCoy, MA; McCracken, RJ | 1 |
| Kennedy, DG; McCracken, RJ | 2 |
| Asai, H; Endo, T; Iwata, H; Katayama, T; Kato, M; Narita, H | 1 |
| Erwin, ME; Jones, RN; Worth, S | 1 |
| Barrett, VJ; Buckingham, J; Giles, H; Honey, AC; MacLennan, SJ; Martin, GR; Moncada, S; Prentice, DJ; Robertson, AD | 1 |
| Barbachyn, MR; Ford, CW; Hamel, JC; Hutchinson, DK; Moerman, JK; Stapert, D; Zurenko, GE | 1 |
| Goadsby, PJ; Knight, YE | 1 |
| Chittick, G; Dixon, RM; Gibbens, M; Leavens, WJ; Liptrot, J; On, N; Pack, RW; Posner, J; Rolan, PE; Seaber, E | 1 |
| Goadsby, PJ | 3 |
| Schoenen, J | 1 |
| Dahlöf, C | 1 |
| Horie, T; Kagei, Y; Kakiki, M; Kawaguchi, S; Naitoh, T | 1 |
| Ishizuka, T | 1 |
| Furuya, N; Koizimi, T; Sebata, H | 1 |
| Gotoh, Y; Kagitani, F; Kimura, A; Nakayama, H; Sato, A | 1 |
| Batts, DH; Daley-Yates, PT; Pawsey, SD; Schaadt, RD; Stalker, DJ; Zurenko, GE | 1 |
| Lin, AH; Marotti, KR; Murray, RW; Vidmar, TJ | 1 |
| Buysse, JM; Demyan, WF; Dunyak, DS; Lin, AH; Marotti, KR; Melchior, EP; Murray, RW; Shinabarger, DL; Swaney, SM | 1 |
| Dixon, RM; Evans, DH; Meire, HB; On, N; Posner, J; Rolan, PE; Watt, H | 1 |
| Castro, ME; Pascual, J; Pazos, A | 1 |
| Andoh, T; Horie, T; Kagei, K; Kakiki, M; Kawaguchi, S; Matsui, K; Mishima, M; Naitoh, T; Yuzuriha, T | 1 |
| Horie, T; Kakiki, M; Kozaki, T; Mishima, M; Naitoh, T; Yuzuriha, T | 1 |
| Cutrer, FM; Moskowitz, MA | 1 |
| Adelman, JU; Earl, NL; Elkind, AH; Kudrow, DB; Mathew, NT; Ramadan, NM; Rapoport, AM | 1 |
| Cady, RK; Earl, NL; Klapper, JA; Ramadan, NM; Saper, JR; Solomon, GD | 1 |
| Mathew, N | 1 |
| Dixon, R; Warrander, A | 1 |
| Rolan, P | 1 |
| Sawyer, J; Schoenen, J | 1 |
| Edmeads, JG; Millson, DS | 1 |
| Lipton, RB; Stewart, WF | 1 |
| Biedenbach, DJ; Jones, RN | 1 |
| Bagnis, C; Deray, G; Gillotin, C; Mamet, JP; Peck, RW | 1 |
| Dixon, R; Gillotin, CG; Layton, G; Peck, RW; Posner, J; Seaber, EJ; Weatherley, BC | 1 |
| Goadsby, PJ; Storer, RJ | 1 |
| Afra, J; Proietti-Cecchini, A; Schoenen, J | 1 |
| Layton, G; Peck, RW; Posner, J; Ridout, G; Seaber, EJ | 1 |
| Colpaert, FC; John, GW; Pagniez, F; Valentin, JP; Vieu, S | 1 |
| Iwata, H; Katayama, T; Kato, M; Matsuoka, Y; Narita, H; Yamamura, M | 1 |
| Arnold, G; Back, T; Dirnagl, U; Dreier, J; Einhäupl, KM; Gold, L; Reuter, U | 1 |
| Aeschlimann, JR; Cappelletty, DM; Kaatz, GW; Moldovan, T; Rybak, MJ | 1 |
| Burghardt, H; Müller, M; Schimz, KL | 1 |
| Dixon, RM; Jackson, SH; Layton, GR; Peck, RW; Posner, J; Rolan, PE; Seaber, EJ; Weatherley, BC | 1 |
| Marotti, KR; Murray, RW; Schaadt, RD; Zurenko, GE | 1 |
| Horie, T; Kajiwara, A; Kakiki, M; Kawaguchi, S; Naitoh, T; Ohe, H | 1 |
| Guanci, R; Lilley, LL | 1 |
| Cleary, EW; Huffman, CS; Polvino, WJ; Smith, DA; Watkins, S | 1 |
| Cleary, EW; Dilzer, SC; Huffman, CS; Lasseter, KC; Smith, DA; Watkins, S | 1 |
| Delvaux, M; Dixon, R; French, S; Kemp, J; Leclerc, V; Rautureau, J; Sellers, M | 1 |
| John, GW; Le Grand, B; Vié, B | 1 |
| Adamski, JL; Allwine, DA; Barbachyn, MR; Brickner, SJ; Burton, PS; Conradi, RA; Ford, CW; Grega, KC; Hutchinson, DK; Jensen, RM; Klock, JL; Tucker, JA; Zurenko, GE | 1 |
| Förderreuther, S; Straube, A; Werhahn, KJ | 1 |
| Dixon, R; Hughes, AM; Kemp, JV; Nairn, K; Sellers, M; Yates, RA | 1 |
| Allanson, J; Hefting, NR; Jonkman, JH; Peck, RW; Seaber, EJ; Smith, DA; Sollie, FA; van Lier, JJ; Wemer, J | 1 |
| Aoki, H; Ganoza, MC; Shinabarger, DL; Swaney, SM | 1 |
| Pascual, J | 1 |
| Leira, R; Noya, M | 1 |
| Morales Asín, F | 1 |
| Cambridge, D; MacLennan, SJ; Marston, C; Martin, GR; Whiting, MV | 1 |
| Cumberbatch, MJ; Hargreaves, RJ; Hill, RG | 1 |
| Lohman, JJ; van der Kuy, PH | 1 |
| Meijler, W | 1 |
| Gibbens, M; Lamb, RJ; Mercer, AJ; Posner, J; Rolan, PE | 1 |
| Monseu, G; Sternon, J | 1 |
| Diener, HC; Fritsche, G; Kazarawa, Z; Limmroth, V | 1 |
| Andrews, JM; Ashby, JP; Boswell, FJ; Wise, R | 1 |
| Moellering, RC | 2 |
| Aoki, Y; Nohira, H; Yamamoto, M; Yoshida, S | 1 |
| Hopkins, B; McHarg, A; Melrose, H; Napier, C; Stewart, M; Wallis, R | 1 |
| Kruzynski, J; Noskin, GA; Peterson, LR; Siddiqui, F; Stosor, V | 1 |
| Cummings, L; Dane, A; Dixon, R; Hughes, AM; Kemp, J; Yates, RA | 1 |
| Chase, S; Cynamon, MH; Klemens, SP; Sharpe, CA | 1 |
| Peters, G; von Eiff, C | 1 |
| Patel, R; Piper, KE; Rouse, MS; Steckelberg, JM | 1 |
| Hamilton-Miller, JM; Shah, S | 1 |
| Dixon, R; Engleman, K; Kemp, J; Ruckle, JL | 1 |
| Hoizey, G; Kaltenbach, ML; Lamiable, D; Vistelle, R; Zbierski, L | 1 |
| Bard, JA; Branchek, T; Edvinsson, L; Longmore, J; Nilsson, T; Pantev, E; Shaw, D | 1 |
| Bungay, PJ; George, SE; Kemp, DM; Naylor, LH | 1 |
| Birk, KL; Cohen, AF; De Puy, ME; De Smet, M; Fisher, AL; Goldberg, MR; Musson, DG; Sterrett, A; Van Gerven, JM; Van Haarst, AD | 1 |
| Barbadora, K; Green, M; Kearney, JA; Mason, EO; Wald, ER | 1 |
| Fresnadillo, MJ; García-Rodríguez, JA; García-Sánchez, E; García-Sánchez, JE; Montes Martínez, I; Trujillano-Martín, I | 1 |
| Deleu, D; Hanssens, Y | 2 |
| Hacek, D; Noskin, GA; Peterson, LR; Siddiqui, F; Stosor, V | 1 |
| Hoppe, JE | 1 |
| Bhagwagar, Z; Cowen, PJ; Whale, R | 1 |
| Gunasekara, NS; Hills, C; Spencer, CM | 1 |
| Aoki, T; Chimoto, T; Hosokawa, S; Sagami, F; Sato, G; Sumigama, S; Tsukidate, K | 1 |
| Mochizuki, N; Nohira, H; Yamamoto, M; Yoshida, S | 1 |
| Diener, HC; Limmroth, V | 1 |
| Sköld, O | 1 |
| Buzzi, MG | 1 |
| Antony, SJ; Bitter, KM; Diaz-Luna, H; Moreland, T; Raudales, F | 1 |
| Le Jeunne, C | 1 |
| Dixon, R | 1 |
| Butters, CJ; McKillop, D; Wild, MJ | 1 |
| Kloss, P; Mankin, AS; Shinabarger, DL; Xiong, L | 1 |
| Diener, HC; Dowson, AJ; Ferrari, M; Nappi, G; Tfelt-Hansen, P | 1 |
| Eliopoulos, GM; Moellering, RC; Schülin, T; Thauvin-Eliopoulos, C | 1 |
| Hopkins, NK; Jungbluth, GL; Sisson, TL | 1 |
| Abdel-Rahman, SM; Kearns, GL | 1 |
| Chien, JW; Kucia, ML; Salata, RA | 1 |
| Heinzl, S; Holtfoht, A; Roloff, T; Ziegler, A | 1 |
| Amelin, AV; Korenko, LA; Skoromets, AA | 1 |
| Bartlett, MG; Stewart, JT; Vishwanathan, K | 1 |
| Bomhof, MA; Donnan, GA; Dowson, AJ; Elkind, A; Fletcher, PE; Meloche, J; Millson, DS; Tepper, SJ | 1 |
| Edvinsson, L; Geraud, G; Korczyn, A; Mauskop, A; Pfaffenrath, V; Tuchman, M | 1 |
| Farkkila, M; Hering-Hanit, R; Mauskop, A; Rapoport, A; Warner, J | 1 |
| Logemann, CD; Rankin, LM | 1 |
| Johnson, AP; Livermore, DM; Warner, M | 1 |
| Millson, DS | 1 |
| Chalimoniuk, M; Stepień, A; Strosznajder, J | 1 |
| Ferrari, MD; Lamers, FP; Roon, KI; Sándor, PS; Schoenen, J; Schoonman, GG; van Dijk, JG | 1 |
| Chandrasekar, PH; Clark, NM; Kauffman, CA; McNeil, SA | 1 |
| Albut, R; Figueira, M; Pelton, SI; Stalker, D | 1 |
| Aoyama, H; Aoyama, M; Chiba, K; Igarashi, M; Murata, S; Ozawa, N; Peng, GW; Stryd, RP; Zenki, T | 1 |
| Nater, B; Regli, F | 1 |
| Diekema, DI; Jones, RN | 1 |
| Grucz, RG; Hershberger, E; Moldovan, T; Rybak, MJ | 1 |
| Peacock, JH; Vijayan, N | 1 |
| Chitra, R; Dennish, G; Gallagher, RM; Spierings, EL | 1 |
| Bowersock, TL; Ford, CW; Portis, ES; Prescott, JF; Robison, DA; Salmon, SA; Watts, JL | 1 |
| MacConnachie, AM | 1 |
| Duckmanton, L | 1 |
| Senior, K | 1 |
| Bahra, A; Breen, SA; Gawel, MJ; Goadsby, PJ; Hardebo, JE; Millson, D | 1 |
| Clemett, D; Markham, A | 1 |
| Diener, HC; Geraud, G; Olesen, J; Pfaffenrath, V; Sweet, R; Tfelt-Hansen, P; Zupping, R | 1 |
| Lundstrom, TS; Sobel, JD | 1 |
| Crimmins, MT; Emmitte, KA | 1 |
| Fines, M; Leclercq, R | 1 |
| Bjork, JM; Dougherty, DM; Marsh, DM; Moeller, FG; Swann, AC; Van de Kar, LD | 1 |
| John, GW; Le Grand, B; Panissié, A; Pauwels, PJ; Perez, M | 1 |
| Chernyshev, O; Gentry, P; Kailasam, J; Mathew, NT | 1 |
| Betriu, C; Boloix, A; Culebras, E; Gómez, M; Palau, ML; Picazo, JJ; Redondo, M; Sánchez, A | 1 |
| Apfalter, P; Hirschl, AM; Makristathis, A; Rotter, ML; Wimmer, M | 1 |
| de Tommaso, M; Guido, M; Libro, G; Puca, F; Sciruicchio, V | 1 |
| Bartleson, JD | 1 |
| Hauer, MJ; Wienkers, LC; Wynalda, MA | 1 |
| Flanagan, PG; Penrose-Stevens, A; Pitman, I; Simpson, BA; Tan, TY | 1 |
| Boggs, CM; Bush, K; Foleno, BD; Goldschmidt, RM; Hlasta, DJ; Weidner-Wells, MA; Wira, E | 1 |
| Aoki, H; Gadwood, RC; Ganoza, MC; Ke, L; Poel, TJ; Poppe, SM; Shinabarger, DL; Thomas, RC; Weaver, EA | 1 |
| Anderegg, TR; Biedenbach, DJ; Jones, RN | 1 |
| Chen, DL; Chen, QH; Shen, XL; Wang, FP; Zhou, XL | 1 |
| Korhonen, H; Pihlava, JM; Ryhänen, EL; Taipale, M; Tolonen, M; Viander, B | 1 |
| Dixon, R; Nairn, K; Seaber, E; Yates, R | 1 |
| Dane, AL; Dixon, R; Kemp, JV; Nairn, K; Yates, R | 1 |
| Barbachyn, MR; Ford, CW; Zurenko, GE | 1 |
| Chen, K; Cui, Y; Ji, R; Yang, Y; Zhang, S | 1 |
| ALTAMURA, MR; HASSELSTROM, T; LONG, L | 1 |
| SWIRSKA, A | 1 |
| MICHALSKI, K; SWIRSKA, A | 1 |
| TANAKA, N; UMEZAWA, H | 1 |
| ABITBOL, H; ORTIZGUEVARA, ER; TEIXIDOR, R | 1 |
| BICKING, JB; FISHER, MH; KWONG, SF; NICHOLSON, WH | 1 |
| BLAUG, SM; RICH, AG | 1 |
| BANKER, GS; WOLFSON, BB | 1 |
| GREER, MA; OGINSKY, EL; STEIN, AE | 1 |
| CRESCENZI, E; DONINI, F; MARAZZIUBERTI, E | 1 |
| Colleran, E; Cormican, M; Curtin, J; Fleming, G; Keelehan, J | 1 |
| Davies, SG; Hughes, DG; Nicholson, RL; Smith, AD; Wright, AJ | 1 |
| Formaggio, F; Galeazzi, R; Garavelli, M; Luppi, G; Tomasini, C | 1 |
| Kapadnis, PB; Lohray, BB; Lohray, VB; Pandya, P; Srivastava, BK | 1 |
| Agrawal, AK; Desai, RC; Franklin, RB; Hop, CE; Leung, KH; Pang, J; Silva Elipe, MV | 1 |
| Rao, M; Rattan, A; Singhal, S; Sood, R | 1 |
| Arora, SK; Dixit, PP; Jain, S; Nair, PS; Patil, VJ; Sinha, N | 1 |
| Bronson, J; Clark, J; D'Andrea, S; Denbleyker, K; Fung-Tomc, JC; Taylor, D; Yang, H; Zheng, ZB | 1 |
| Gravestock, MB | 1 |
| Arora, SK; Bhateja, P; Das, B; Malhotra, S; Mathur, T; Mehta, A; Pandya, M; Rao, AV; Rattan, A; Ray, A; Rudra, S; Saini, S; Shukla, S; Soni, A; Srinivas, AS; Yadav, A | 1 |
| Brieland, JK; Chosay, JG; Leach, KL; Nagiec, EE; Ross, DE; Swaney, SM; Wu, L | 1 |
| Das, J; Iqbal, J; Khera, MK; Selvakumar, N; Sitaram Kumar, M; Srinivas, D; Sunil Kumar, G; Trehan, S; Yadi Reddy, B | 1 |
| Bansal, V; Das, B; Gupta, JB; Naruganahalli, KS; Ray, A; Shirumalla, RK | 1 |
| Choi, SH; Gonzalez, E; Molina-Torres, C; Ocampo-Candiani, J; Rendon, A; Velazquez-Moreno, VM; Vera-Cabrera, L; Welsh, O | 1 |
| Brown-Elliott, BA; Choi, SH; Molina-Torres, CA; Ocampo-Candiani, J; Vera-Cabrera, L; Wallace, RJ; Welsh, O | 1 |
| Chollet, G; Guillerez, MG; Schulz, E | 1 |
| Bae, SK; Lee, MG; Rhee, JK; Shin, KN; Yang, SH; Yoo, M | 1 |
| Cavazos-Rocha, N; Choi, SH; de Torres, NW; Espinoza-González, NA; Lozano-Garza, G; Ocampo-Candiani, J; Said-Fernandez, S; Vera-Cabrera, L; Welsh, O | 1 |
| Nau, JY | 1 |
| Arora, P; Barman, TK; Bhadauriya, T; Rao, M; Upadhyay, DJ | 1 |
| Bhateja, P; Bhatnagar, PK; Fatma, T; Khan, S; Mathur, T; Pandya, M; Rattan, A; Singhal, S; Upadhyay, DJ | 1 |
| Baumgardt, I; Butenschön, H; Cao, W; Erden, I; Gärtner, C; Hoarau, C; Ozer, G; Song, J | 1 |
| Ercan, A; Jayaprakash, V; Sinha, BN; Ucar, G | 1 |
| Kalia, V; Khan, S; Mathur, T; Miglani, R; Purnapatre, KP; Raj, VS; Rattan, A; Saini, KS; Singhal, S; Upadhyay, DJ; Voleti, SR | 1 |
| Das, B; Mehta, A; Pandya, M; Rajarao, AV; Rattan, A; Ray, A; Rudra, S; Yadav, A | 1 |
| Brown, SD; Traczewski, MM | 1 |
| Bien, P; Bulitta, JB; Corey, GR; DeAnda, C; Mehra, P; Prokocimer, P; Surber, J | 1 |
| Drusano, GL; Kulawy, R; Liu, W; Louie, A | 2 |
| Harvey, JS; Jamison, CR; MacMillan, DW; Simonovich, SP | 1 |
| Břicháč, J; Douša, M; Gibala, P; Klecán, O; Mandelová, Z; Pekárek, T; Rádl, S | 1 |
| Bartizal, K; Bien, P; Deanda, C; Pillar, CM; Prokocimer, P | 1 |
| Bartizal, K; Choi, S; Im, W | 1 |
| Andes, DR; Craig, WA; Lepak, AJ; Marchillo, K; Pichereau, S | 1 |
| Ide, S; Minami, M; Nakamura, K; Saito, N; Sato, Y; Shibano, S | 1 |
| Bartizal, K; Fang, E; Flanagan, S; Minassian, SL; Prokocimer, P | 1 |
| Bartizal, K; Locke, JB; Shaw, KJ; Zurenko, GE | 1 |
| Bien, P; De Anda, C; Prokocimer, P | 1 |
| PIEPOLI, CR; YURCHENCO, JA; YURCHENCO, MC | 1 |
| Jeong, BH; Koh, WJ; Kwon, YS | 1 |
| Kotapalli, SS; Naresh, A; Ummanni, R; Venkateswara Rao, B; Venkateswara Rao, M | 1 |
| Corey, GR; Das, AF; De Anda, C; Fang, E; Moran, GJ; Prokocimer, P | 1 |
| Kern, WV; Tacconelli, E | 1 |
| Cao, J; Chen, H; He, W; Hu, D; Li, H; Liu, Y; Ma, X; Wang, H; Wang, Q; Wang, X; Wang, Z; Wu, W; Xia, F; Yang, Q; Zhang, F; Zhang, J; Zhang, R; Zhao, C; Zhao, F | 1 |
| Deane, J; Goering, RV; Jenkins, SG; Locke, JB; Sahm, DF; Scharn, CR; Shaw, KJ; Zuill, DE | 1 |
| Alcorn, HW; Fang, E; Flanagan, S; Marbury, TC; Minassian, SL; Morris, D; Ponnuraj, R; Prokocimer, P | 1 |
| Fiedler-Kelly, J; Flanagan, S; Lu, Q; Ludwig, E; Passarell, J; Prokocimer, P | 1 |
| Bensaci, M; Bien, P; Patel, HN; Thorne, G; Zurenko, G | 1 |
| Chang, KC; Heyckendorf, J; Lange, C; Olaru, ID; von Groote-Bidlingmaier, F; Yew, WW | 1 |
| Bartizal, KF; Bien, PA; Deane, J; Locke, JB; Sahm, DF; Shaw, KJ; Zuill, DE | 1 |
| Drekonja, DM | 1 |
| Taylor, J | 1 |
| Corey, GR; Das, AF; Moran, GJ; Prokocimer, P | 1 |
| Ang, W; Chang, Y; Chen, G; Li, G; Liu, Y; Long, H; Luo, Y; Sang, Z; Tang, J; Wang, Z; Wei, Y; Yang, S; Yang, T; Yang, X; Zhang, J | 1 |
| Douros, A; Grabowski, K; Stahlmann, R | 1 |
| Betoudji, F; Converse, PJ; Dartois, V; Li, SY; Mdluli, KE; Mendel, CM; Nuermberger, EL; Tasneen, R; Tyagi, S; Williams, K; Yang, T | 1 |
| Chellat, MF; Raguž, L; Riedl, R | 1 |
| Iqbal, M | 1 |
| Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
| Arber, M; Barata, T; Eales, J; Fleetwood, K; Glanville, J; Gould, IM; Kauf, TL; McCool, R | 1 |
| Al-Huniti, N; Birmingham, B; Li, J; Lillieborg, S; Xu, H; Zhou, D; Zhou, W | 1 |
| Calabuig Muñoz, E; Castells Lao, G; Isernia, V; López Suñé, E; Mensa Pueyo, J; Mensa Vendrell, M; Morata Ruiz, L; Moreno Nuñez, L; Oltra Sempere, MR; Pasquau Liaño, J; Pedro-Botet Montoya, ML; Reynaga Sosa, EA; Salavert Lletí, M; Sequera Arquelladas, S; Soriano Viladomiu, A; Tasias Pitarch, M; Yuste Ara, JR | 1 |
| Causgrove, C; Dartois, V; Drusano, GL; Flynn, JL; Graham, E; Kim, S; Louie, A; Miranda Silva, C; Peloquin, CA; Scanga, CA; Schmidt, S; Stein, B; Zimmerman, M | 1 |
| Mori, M; Takase, A | 1 |
| Nath, A; Penewit, K; Salipante, SJ; Shen, T; Waalkes, A; Werth, BJ; Xu, L | 1 |
| Choi, H; Choi, J; Jang, H; Lee, K | 1 |
| Kase, M; Kitaoka, A; Kobayashi, S; Matsubara, M; Yasu, T | 1 |
| Cabañero-Navalon, MD; García-Bustos, V; Morata Ruiz, L; Salavert Lletí, M | 1 |
| Iqbal, K; Milioudi, A; Wicha, SG | 1 |
| Amann, LF; Huang, J; Iqbal, K; Rohde, H; Tikiso, T; Wicha, SG; Zeitlinger, M | 1 |
45 review(s) available for oxazoles and oxazolidin-2-one
| Article | Year |
|---|---|
Pharmacology of the glutamate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Antidepressive Agents; Azepines; Glutamates; Glutamic Acid; Membrane Potentials; Nervous System Diseases; Neurons; Oxazoles; Oxazolidinones; Piperidines; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1988 |
Some aspects of monoamine oxidase pharmacology.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Arteries; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Muscle, Smooth; Oxazoles; Oxazolidinones; Rats; Selegiline; Semicarbazides; Vas Deferens | 1986 |
Overview of the present state of MAO inhibitors.
Topics: Animals; Benzamides; Humans; Hydrazines; Isoquinolines; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Parkinson Disease; Phenethylamines; Piperidines; Selegiline; Structure-Activity Relationship | 1987 |
The current status of monoamine oxidase and its inhibitors.
Topics: Allylamine; Benzamides; Clinical Trials as Topic; Humans; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Selegiline | 1987 |
The clinical effectiveness of 311C90 in the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Multicenter Studies as Topic; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Clinical safety of 311C90: aggregated data from patients and volunteers to date.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
Inhibition of the trigemino-vascular system with 5-HT1D agonist drugs: selectively targeting additional sites of action.
Topics: Administration, Oral; Biological Availability; Cerebrovascular Circulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
Emerging preclinical and clinical profile of 311C90: a poster review and discussion.
Topics: Animals; Central Nervous System; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Tryptamines | 1996 |
Increasing the options for effective migraine management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Ergotamine; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
311C90: increasing the options for therapy with effective acute antimigraine 5HT1B/1D receptor agonists.
Topics: Headache; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Oxazolidinones: new antibacterial agents.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Community-Acquired Infections; Cross Infection; Humans; Oxazoles; Oxazolidinones; Penicillin Resistance | 1997 |
[Synthetic 2-amino alcohol derivatives as chiral auxiliaries].
Topics: Acylation; Amino Alcohols; Chemistry, Organic; Molecular Conformation; Organic Chemistry Phenomena; Oxazoles; Oxazolidinones; Oxazolone; Stereoisomerism | 1997 |
Zolmitriptan. Introduction.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1997 |
Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine.
Topics: Administration, Oral; Animals; Biological Availability; Drug Evaluation, Preclinical; Hemodynamics; Injections, Intravenous; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Potential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90).
Topics: Acetaminophen; Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Ergotamine; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 1997 |
Clinical applications of zolmitriptan (Zomig, 311C90).
Topics: Acute Disease; Disabled Persons; Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Mechanism of action of zolmitriptan].
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
[Clinical efficacy of zolmitriptan in migraine].
Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
[Safety profile of 311C90 (zolmitriptan)].
Topics: Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.
Topics: Acute Disease; Animals; Clinical Trials as Topic; Coronary Circulation; Coronary Vasospasm; Drug Design; Drug Interactions; Humans; Inactivation, Metabolic; Indoles; Meninges; Migraine Disorders; Molecular Structure; Nociceptors; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Pyrrolidines; Randomized Controlled Trials as Topic; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Recurrence; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents | 1999 |
Zolmitriptan: a review of its use in migraine.
Topics: Age Factors; Clinical Trials as Topic; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Acute management of migraine: triptans and beyond.
Topics: Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
[Zolmitriptan].
Topics: Drug Costs; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Selection; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1999 |
The scientific basis of medication choice in symptomatic migraine treatment.
Topics: Acute Disease; Choice Behavior; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Triazoles; Tryptamines | 1999 |
An update on the oxazolidinone antibiotics.
Topics: Acetamides; Anti-Infective Agents; Drug Resistance, Microbial; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1999 |
[Oxazolidinones. A new anti-infective principle].
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1999 |
Newer intranasal migraine medications.
Topics: Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Clinical Trials as Topic; Dihydroergotamine; Half-Life; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2000 |
How effective are triptans in the treatment of episodic and chronic cluster headache.
Topics: Chronic Disease; Cluster Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Oxazolidinones: a review.
Topics: Acetamides; Animals; Anti-Infective Agents; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 2000 |
New antibiotics for gram positive infections: linezolid and combination quinapristin/dalfopristin.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Drug Prescriptions; Drug Resistance, Microbial; Drug Therapy, Combination; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazoles; Oxazolidinones; Safety; Virginiamycin | 1999 |
Linezolid.
Topics: Acetamides; Animals; Bacteria; Bacterial Infections; Humans; Linezolid; Oxazoles; Oxazolidinones | 2000 |
Antibiotics for gram-positive bacterial infections. Vancomycin, teicoplanin, quinupristin/dalfopristin, and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazoles; Oxazolidinones; Teicoplanin; Vancomycin; Virginiamycin | 2000 |
Current and emerging second-generation triptans in acute migraine therapy: a comparative review.
Topics: Acute Disease; Carbazoles; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2000 |
The discovery of linezolid, the first oxazolidinone antibacterial agent.
Topics: Acetamides; Anti-Bacterial Agents; Gram-Negative Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Structure-Activity Relationship | 2001 |
Recent developments in the discovery of novel oxazolidinone antibacterials.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Linezolid; Oxazoles; Oxazolidinones | 2005 |
Tedizolid: a novel oxazolidinone for Gram-positive infections.
Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Organophosphates; Oxazoles; Oxazolidinones | 2014 |
Tedizolid for the management of human infections: in vitro characteristics.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Humans; Linezolid; Organophosphates; Oxazoles; Oxazolidinones; Point Mutation; Ribosomal Protein L3; Ribosomal Proteins; RNA, Ribosomal, 23S; Staphylococcal Infections; Staphylococcus aureus; tRNA Methyltransferases | 2014 |
Tuberculosis: clinical trials and new drug regimens.
Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2014 |
Novel drugs against tuberculosis: a clinician's perspective.
Topics: Adamantane; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarylquinolines; Drug Therapy, Combination; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Nitroimidazoles; Oxazoles; Oxazolidinones; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2015 |
Drug-drug interactions and safety of linezolid, tedizolid, and other oxazolidinones.
Topics: Animals; Anti-Bacterial Agents; Drug Interactions; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Organophosphates; Oxazoles; Oxazolidinones; Structure-Activity Relationship | 2015 |
Targeting Antibiotic Resistance.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Drug Design; Drug Resistance, Multiple, Bacterial; Macrolides; Molecular Dynamics Simulation; Organophosphates; Oxazoles; Oxazolidinones; Structure-Activity Relationship | 2016 |
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
Systematic review and network meta-analysis of tedizolid for the treatment of acute bacterial skin and skin structure infections caused by MRSA.
Topics: Anti-Bacterial Agents; Bayes Theorem; Ceftaroline; Cephalosporins; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; Staphylococcal Infections; Tetrazoles; Vancomycin | 2017 |
Tedizolid: new data and experiences for clinical practice.
Topics: Anti-Bacterial Agents; Humans; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Tetrazoles | 2021 |
Pharmacokinetics and Pharmacodynamics of Tedizolid.
Topics: Animals; Anti-Bacterial Agents; Humans; Mice; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Tetrazoles | 2022 |
61 trial(s) available for oxazoles and oxazolidin-2-one
| Article | Year |
|---|---|
A study of metaxalone (Skelaxin) vs. placebo in acute musculoskeletal disorders: a cooperative study.
Topics: Anthropometry; Clinical Trials as Topic; Drug Evaluation; Humans; Inflammation; Muscular Diseases; Oxazoles; Oxazolidinones; Pain; Placebos; Spasm; Wounds and Injuries | 1975 |
Pharmacokinetic and pharmacodynamic interaction between toloxatone, a new reversible monoamine oxidase-A inhibitor, and oral tyramine in healthy subjects.
Topics: Administration, Oral; Analysis of Variance; Blood Pressure; Drug Synergism; Humans; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Reference Values; Single-Blind Method; Tyramine | 1992 |
A double-blind comparison of moclobemide and toloxatone in out-patients presenting a major depressive disorder.
Topics: Adult; Antidepressive Agents; Benzamides; Depressive Disorder; Double-Blind Method; Humans; Moclobemide; Outpatients; Oxazoles; Oxazolidinones; Psychiatric Status Rating Scales; Psychomotor Performance | 1992 |
Comparative investigation of the effect of moclobemide and toloxatone on monoamine oxidase activity and psychometric performance in healthy subjects.
Topics: Adult; Arousal; Benzamides; Biogenic Monoamines; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Male; Memory; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Psychomotor Performance; Sleep | 1992 |
Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects.
Topics: Adult; Benzamides; Double-Blind Method; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Psychometrics; Psychophysiology | 1990 |
[Toloxatone and depression].
Topics: Adolescent; Adult; Aged; Depression; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Psychiatric Status Rating Scales; Psychometrics | 1991 |
The current status of monoamine oxidase and its inhibitors.
Topics: Allylamine; Benzamides; Clinical Trials as Topic; Humans; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Selegiline | 1987 |
[Antidepressive action, pharmacokinetic characteristics and biochemical properties of cimoxatone, a new reversible MAO-A inhibitor].
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Kinetics; Male; Methoxyhydroxyphenylglycol; Middle Aged; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Prolactin | 1983 |
Effect of a reversible and selective MAO-A inhibitor (cimoxatone) on diurnal variation in plasma prolactin level in man.
Topics: Adult; Circadian Rhythm; Humans; Hydrocortisone; Kinetics; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Prolactin | 1984 |
Pharmacologic effect of toloxatone on reactivity to the 35% carbon dioxide challenge: a single-blind, random, placebo-controlled study.
Topics: Administration, Inhalation; Administration, Oral; Adult; Agoraphobia; Antidepressive Agents; Arousal; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Panic; Panic Disorder; Single-Blind Method | 1994 |
A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy.
Topics: Analgesics; Capsaicin; Diabetic Neuropathies; Exercise Therapy; Female; Glycated Hemoglobin; Humans; Imipramine; Male; Mexiletine; Middle Aged; Models, Neurological; Muscles; Oxazoles; Oxazolidinones; Pain; Pain Management; Pain Measurement; Piroxicam | 1993 |
311C90, a new central and peripherally acting 5-HT1D receptor agonist in the acute oral treatment of migraine: a double-blind, placebo-controlled, dose-range finding study.
Topics: Administration, Oral; Adolescent; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Pain Measurement; Placebos; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1996 |
Evaluation of the long-term safety and efficacy of 311C90 in the treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Child; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Can oral 311C90, a novel 5-HT1D agonist, prevent migraine headache when taken during an aura?
Topics: Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; United Kingdom | 1996 |
The tolerability and pharmacokinetics of the novel antimigraine compound 311C90 in healthy male volunteers.
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
311C90: long-term efficacy and tolerability profile for the acute treatment of migraine. International 311C90 Long-Term Study Group.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Research Design; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90) in healthy volunteers.
Topics: Administration, Oral; Adult; Analysis of Variance; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Zolmitriptan: new perspectives in migraine therapy. Satellite symposium of the 11th Migraine Trust International Symposium, London, 10 September 1996].
Topics: Blood-Brain Barrier; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Sumatriptan; Tryptamines | 1997 |
The absolute bioavailability and metabolic disposition of the novel antimigraine compound zolmitriptan (311C90).
Topics: Absorption; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Feces; Female; Half-Life; Humans; Indoleacetic Acids; Infusions, Intravenous; Male; Mass Spectrometry; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sex Factors; Tryptamines | 1997 |
Serum inhibitory titers and serum bactericidal titers for human subjects receiving multiple doses of the antibacterial oxazolidinones eperezolid and linezolid.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Injections, Intravenous; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae | 1997 |
Peripheral vascular effects and pharmacokinetics of the antimigraine compound, zolmitriptan, in combination with oral ergotamine in healthy volunteers.
Topics: Administration, Oral; Adult; Biological Availability; Blood Pressure; Caffeine; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Ergotamine; Female; Humans; Intestinal Absorption; Male; Oxazoles; Oxazolidinones; Pulse; Reference Values; Serotonin Receptor Agonists; Tryptamines; Vasoconstrictor Agents | 1997 |
Optimizing the dose of zolmitriptan (Zomig, 311C90) for the acute treatment of migraine. A multicenter, double-blind, placebo-controlled, dose range-finding study. The 017 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
Clinical efficacy and tolerability of 2.5 mg zolmitriptan for the acute treatment of migraine. The 042 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Zolmitriptan (Zomig, 311C90), a novel dual central and peripheral 5HT1B/1D agonist: an overview of efficacy.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Female; Humans; Menstruation; Middle Aged; Migraine Disorders; Nausea; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
Tolerability profile of zolmitriptan (Zomig; 311C90), a novel dual central and peripherally acting 5HT1B/1D agonist. International clinical experience based on > 3000 subjects treated with zolmitriptan.
Topics: Administration, Oral; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Cardiovascular System; Child; Humans; Incidence; Middle Aged; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
No need to adjust the dose of 311C90 (zolmitriptan), a novel anti-migraine treatment, in patients with renal failure not requiring dialysis.
Topics: Adult; Aged; Area Under Curve; Blood Pressure; Electrocardiography; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Renal Dialysis; Serotonin Receptor Agonists; Tryptamines | 1997 |
The interaction between propranolol and the novel antimigraine agent zolmitriptan (311C90).
Topics: Adrenergic beta-Antagonists; Adult; Area Under Curve; Biotransformation; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Electrocardiography; Female; Half-Life; Humans; Male; Oxazoles; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Tryptamines | 1997 |
Intensity dependence of the cortical auditory evoked potentials as a surrogate marker of central nervous system serotonin transmission in man: demonstration of a central effect for the 5HT1B/1D agonist zolmitriptan (311C90, Zomig).
Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1997 |
The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide.
Topics: Acetaminophen; Adult; Blood Pressure; Drug Interactions; Female; Humans; Male; Metoclopramide; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The pharmacodynamics and pharmacokinetics of the 5HT1B/1D-agonist zolmitriptan in healthy young and elderly men and women.
Topics: Adult; Age Factors; Aged; Blood Pressure; Central Nervous System; Double-Blind Method; Electrocardiography; Female; Half-Life; Heart Rate; Humans; Male; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Sex Factors; Tryptamines | 1998 |
The long-term tolerability and efficacy of oral zolmitriptan (Zomig, 311C90) in the acute treatment of migraine. An international study. The International 311C90 Long-term Study Group.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1998 |
Zolmitriptan (311C90) does not interact with fluoxetine in healthy volunteers.
Topics: Adolescent; Adult; Cranial Sinuses; Cross-Over Studies; Dizziness; Drug Interactions; Drug Tolerance; Female; Fluoxetine; Humans; Intracranial Pressure; Male; Middle Aged; Nausea; Oxazoles; Oxazolidinones; Patient Compliance; Pharyngitis; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines | 1998 |
Pharmacokinetics and pharmacodynamics of zolmitriptan in patients with mild to moderate hypertension: a double-blind, placebo-controlled study.
Topics: Area Under Curve; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sodium Chloride Symporter Inhibitors; Tryptamines | 1998 |
Effect of hepatic impairment on the pharmacokinetics of zolmitriptan.
Topics: Adult; Aged; Area Under Curve; Biotransformation; Blood Pressure; Female; Half-Life; Humans; Liver Diseases; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Effects of the antimigraine compound zolmitriptan ('Zomig') on psychomotor performance alone and in combination with diazepam in healthy volunteers.
Topics: Adult; Cross-Over Studies; Diazepam; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxazoles; Oxazolidinones; Psychometrics; Psychomotor Performance; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1998 |
The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers.
Topics: Adolescent; Adult; Biological Availability; Cross-Over Studies; Female; Food-Drug Interactions; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Lack of an effect of zolmitriptan (Zomig, 311C90) on psychometric task performance: results of a placebo-controlled study in healthy volunteers.
Topics: Adolescent; Adult; Affect; Anti-Anxiety Agents; Color Perception; Cross-Over Studies; Double-Blind Method; Female; Humans; Lorazepam; Male; Mental Processes; Middle Aged; Oxazoles; Oxazolidinones; Psychometrics; Psychomotor Performance; Reaction Time; Serotonin Receptor Agonists; Tryptamines | 1998 |
Effects of zolmitriptan (Zomig) on central serotonergic neurotransmission as assessed by active oddball auditory event-related potentials in volunteers without migraine.
Topics: Acoustic Stimulation; Adult; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1999 |
A comparison of the pharmacokinetics and tolerability of the novel antimigraine compound zolmitriptan in adolescents and adults.
Topics: Adolescent; Adult; Aged; Aging; Area Under Curve; Biotransformation; Child; Female; Half-Life; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1999 |
The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers.
Topics: Adult; Area Under Curve; Benzamides; Biotransformation; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 1999 |
Zolmitriptan-induced growth hormone release in humans: mediation by 5-HT1D receptors?
Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Female; Human Growth Hormone; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Unbalanced randomization influences placebo response: scientific versus ethical issues around the use of placebo in migraine trials.
Topics: Double-Blind Method; Ethics, Medical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1999 |
A pharmacokinetic evaluation of concomitant administration of linezolid and aztreonam.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Aztreonam; Cross-Over Studies; Drug Interactions; Female; Humans; Linezolid; Male; Middle Aged; Monobactams; Oxazoles; Oxazolidinones | 1999 |
Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Enterococcus; Epidural Abscess; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Oxazoles; Oxazolidinones; Parotitis; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2000 |
A long-term study to maximise migraine relief with zolmitriptan.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 1999 |
Zolmitriptan provides consistent migraine relief when used in the long-term.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Zolmitriptan is effective for the treatment of persistent and recurrent migraine headache.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
[Oral zolmitriptan (Zomig) in the treatment of migraine crisis].
Topics: Administration, Oral; Adolescent; Adult; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2000 |
A comparative trial of zolmitriptan and sumatriptan for the acute oral treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Satisfaction; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2000 |
Oral zolmitriptan is effective in the acute treatment of cluster headache.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Cluster Headache; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Pain Measurement; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2000 |
Comparison of the efficacy of zolmitriptan and sumatriptan: issues in migraine trial design.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2000 |
Low dose zolmitriptan as a 5-HT neuroendocrine challenge agent in humans.
Topics: Adult; Blood Pressure; Body Temperature; Double-Blind Method; Female; Human Growth Hormone; Humans; Hydrocortisone; Kinetics; Male; Neurosecretory Systems; Oxazoles; Oxazolidinones; Placebos; Prolactin; Serotonin Receptor Agonists; Tryptamines | 2000 |
Treatment of nonresponders to oral sumatriptan with zolmitriptan and rizatriptan: a comparative open trial.
Topics: Administration, Oral; Cross-Over Studies; Drug Resistance; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Retreatment; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Preliminary studies of the pharmacokinetics and tolerability of zolmitriptan nasal spray in healthy volunteers.
Topics: Administration, Intranasal; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Male; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 2002 |
Pharmacokinetics, dose proportionality, and tolerability of single and repeat doses of a nasal spray formulation of zolmitriptan in healthy volunteers.
Topics: Administration, Intranasal; Adult; Area Under Curve; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 2002 |
Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Skin Infections; Staphylococcus aureus; Treatment Outcome; Young Adult | 2011 |
In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections.
Topics: Acetamides; Adolescent; Adult; Aged; Anti-Bacterial Agents; Culture Media; Double-Blind Method; Drug Administration Schedule; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Organophosphates; Oxazoles; Oxazolidinones; Skin; Staphylococcal Skin Infections; Staphylococcus; Tetrazoles | 2012 |
In vitro, in vivo, and clinical studies of tedizolid to assess the potential for peripheral or central monoamine oxidase interactions.
Topics: Acetamides; Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Blood Pressure; Female; Humans; Linezolid; Male; Mice; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Organophosphates; Oxazoles; Oxazolidinones; Pseudoephedrine; Serotonin; Serotonin Agents; Tetrazoles; Tyramine; Young Adult | 2013 |
Comparison of digital planimetry and ruler technique to measure ABSSSI lesion sizes in the ESTABLISH-1 study.
Topics: Acetamides; Anti-Bacterial Agents; Erythema; Humans; Image Interpretation, Computer-Assisted; Linezolid; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; United States | 2014 |
Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial.
Topics: Acetamides; Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Linezolid; Male; Middle Aged; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; Treatment Outcome; Young Adult | 2014 |
Pharmacokinetics of tedizolid in subjects with renal or hepatic impairment.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Cross-Over Studies; Female; Humans; Kidney; Kidney Failure, Chronic; Liver; Liver Diseases; Male; Middle Aged; Organophosphates; Oxazoles; Oxazolidinones; Prodrugs; Renal Dialysis; Tetrazoles; Young Adult | 2014 |
307 other study(ies) available for oxazoles and oxazolidin-2-one
| Article | Year |
|---|---|
Monoamine oxidase inhibitory properties of 5-hydroxymethyl-3-m-tolyloxazolidin-2-one (toloxatone).
Topics: Animals; Antidepressive Agents; Brain; Clorgyline; In Vitro Techniques; Kinetics; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats | 1978 |
5-Carboxamido-4-amino-3-isoxazolidone, and asparagine analogue.
Topics: Animals; Antineoplastic Agents; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Isoxazoles; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Oxazolidinones | 1978 |
Monoamine oxidase inhibition and brain amine metabolism after oral treatment with toloxatone in the rat.
Topics: Animals; Antidepressive Agents; Biogenic Amines; Brain; Deamination; Dopamine; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Oxazoles; Oxazolidinones; Oxidation-Reduction; Rats; Serotonin; Synaptosomes; Time Factors | 1979 |
Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.
Topics: Animals; Brain; Cats; Cell Membrane; gamma-Aminobutyric Acid; Muscimol; Neurons; Oxazoles; Oxazolidinones; Rats; Receptors, Drug; Spinal Cord; Structure-Activity Relationship | 1979 |
High-performance liquid chromatographic method for the determination of 5-vinyl-2-oxazolidinethione in milk.
Topics: Animal Feed; Animals; Brassica; Cattle; Chromatography, High Pressure Liquid; Food Contamination; Milk; Oxazoles; Oxazolidinones | 1979 |
Activity of toloxatone and various psychotropic drugs on the electrocorticogram and three limbic structures in the cat.
Topics: Amygdala; Animals; Cats; Cerebral Cortex; Electroencephalography; Evoked Potentials; Hippocampus; Limbic System; Oxazoles; Oxazolidinones; Psychotropic Drugs; Septum Pellucidum | 1977 |
Mammalian spot test with moxnidazole, a 5-nitroimidazole.
Topics: Animals; Embryo, Mammalian; Female; Genotype; Mice; Mutagens; Nitroimidazoles; Oxazoles; Oxazolidinones; Pigmentation; Pregnancy | 1978 |
3-Isoxazolidone--an inhibitor of GABA metabolism.
Topics: Aminobutyrates; Animals; Brain; Chickens; Depression, Chemical; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Isoniazid; Isoxazoles; Male; Mice; Oxazoles; Oxazolidinones; Rats; Seizures; Time Factors | 1976 |
Effects of 5-vinyloxazolidine-2-thione on lactating rats and their sucklings.
Topics: Animals; Animals, Suckling; Antithyroid Agents; Body Weight; Female; Lactation; Leukocyte Count; Male; Organ Size; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Thyroid Gland | 1992 |
Effects of angiotensinase inhibitors on plasma protein binding and IC50 determinations of renin inhibitors.
Topics: Amides; Blood Proteins; Dipeptides; Histidine; Humans; Hydrogen-Ion Concentration; Morpholines; Oxazoles; Oxazolidinones; Oxyquinoline; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Protein Binding; Renin | 1992 |
Toloxatone pharmacokinetics in the plasma and cerebrospinal fluid of the rabbit.
Topics: Animals; Blood-Brain Barrier; Half-Life; Male; Oxazoles; Oxazolidinones; Rabbits; Regression Analysis | 1992 |
Fluorescence quenching studies on binding fluoreno-9-spiro-oxazolidinedione to human serum albumin.
Topics: Algorithms; Fluorenes; Fluorescence; Humans; Oxazoles; Oxazolidinones; Serum Albumin; Temperature | 1992 |
A chiral N-crotonyloxazolidinone Diels-Alder adduct.
Topics: Benzyl Compounds; Butadienes; Molecular Structure; Oxazoles; Oxazolidinones; Stereoisomerism; X-Ray Diffraction | 1992 |
Nutritional value of processed rapeseed meal.
Topics: Amino Acids; Ammonia; Animal Feed; Animals; Antithyroid Agents; Brassica; Chickens; Eating; Energy Intake; Energy Metabolism; Fatty Acids, Monounsaturated; Food Handling; Hydrolysis; Iodine; Isothiocyanates; Male; Minerals; Nutritive Value; Organ Size; Oxazoles; Oxazolidinones; Plant Oils; Rapeseed Oil; Rats; Thiocyanates; Weight Gain | 1991 |
Identification of several human urinary metabolites of 6-benzoyl benzoxazolinone by gas chromatography/mass spectrometry.
Topics: Adult; Analgesics; Benzoxazoles; Biotransformation; Chromatography, Ion Exchange; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Oxazoles; Oxazolidinones | 1991 |
AHR-14310C: a potent, long-acting, nonsedating H1-antihistamine that prevents antigen-induced mucus formation in sensitive rats.
Topics: Acetylcholine; Animals; Cats; Dogs; Drug Hypersensitivity; Female; Guinea Pigs; Histamine Antagonists; Histamine H1 Antagonists; Male; Muscle, Smooth; Oxazoles; Oxazolidinones; Piperidines; Rats; Rats, Inbred Strains; Skin Tests; Sleep | 1990 |
Dual-function radiosensitizers. Alpha-[[(2-bromoethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanol and related compounds: preparation via an aziridine equivalent.
Topics: Acetates; Acetic Acid; Aziridines; Chemical Phenomena; Chemistry; Esterification; Molecular Structure; Nitroimidazoles; Oxazoles; Oxazolidinones; Prodrugs; Radiation-Sensitizing Agents | 1991 |
Stereoselective metabolism of 3-isopropyl-5-(1-naphthoxymethyl)oxazolidine, a prodrug of propranolol.
Topics: Animals; Buffers; Chromatography, High Pressure Liquid; Hydrolysis; Liver; Naphthalenes; Oxazoles; Oxazolidinones; Prodrugs; Propranolol; Rats; Spectrophotometry; Stereoisomerism; Tissue Extracts | 1991 |
Use of pig hepatocytes to study the inhibition of monoamine oxidase by furazolidone.
Topics: Animals; Cells, Cultured; Clorgyline; Furazolidone; Hydrazines; Iproniazid; Liver; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Swine; Tyramine | 1991 |
Effect of organic N-halamines on selected membrane functions in intact Staphylococcus aureus cells.
Topics: Cell Membrane; Cell Membrane Permeability; Disinfectants; Halogens; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Oxazoles; Oxazolidinones; Potassium; Respiration; Staphylococcus aureus | 1991 |
The use of pig hepatocytes to study the nature of protein-bound metabolites of furazolidone: a new analytical method for their detection.
Topics: Animals; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Furazolidone; Microsomes, Liver; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Swine | 1991 |
On the possible involvement of glutamate receptors in conditioning of behavioural effects of apomorphine.
Topics: Animals; Apomorphine; Azepines; Behavior, Animal; Conditioning, Operant; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Motor Activity; Muscle Relaxants, Central; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Stereotyped Behavior | 1990 |
Effect of intrarenal renin inhibition on renal hemodynamics and excretory function.
Topics: Angiotensin II; Animals; Hemodynamics; Histidine; Infusions, Intra-Arterial; Infusions, Intravenous; Kidney; Macaca fascicularis; Male; Oxazoles; Oxazolidinones; Renal Circulation; Renin; Renin-Angiotensin System; Sodium; Urination | 1990 |
Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics.
Topics: Animals; Brassica; Diet; Enzyme Induction; Glutathione Transferase; Intestinal Mucosa; Isothiocyanates; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Rats; Rats, Inbred F344; Thiocyanates; Xenobiotics | 1990 |
[Fatal fulminant hepatitis in 2 women taking toloxatone (Humoryl)].
Topics: Acute Disease; Adult; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Oxazoles; Oxazolidinones; Time Factors | 1990 |
Rhesus monkey cerebrospinal fluid amine metabolite changes following treatment with the reversible monoamine oxidase type-A inhibitor cimoxatone.
Topics: Animals; Biogenic Amines; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones | 1985 |
[The occurrence of goitrogenic substances in milk. 1. Release of goitrin in the milk of cows fed on rapeseed extract cakes].
Topics: Animal Feed; Animals; Antithyroid Agents; Brassica; Cattle; Chromatography, High Pressure Liquid; Milk; Oxazoles; Oxazolidinones; Spectrophotometry, Ultraviolet; Time Factors | 1985 |
Preliminary observations on the effect of dietary brussels sprouts on thyroid function.
Topics: Antithyroid Agents; Brassica; Female; Glucosinolates; Humans; Indoles; Male; Oxazoles; Oxazolidinones; Thioglycosides; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1986 |
The mechanism of action of DuP 721, a new antibacterial agent: effects on macromolecular synthesis.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Chloramphenicol; DNA, Bacterial; Drug Resistance, Microbial; Hygromycin B; Microbial Sensitivity Tests; Mutation; Oxazoles; Oxazolidinones; Peptide Chain Elongation, Translational; RNA, Bacterial; Streptomycin; Tetracycline | 1988 |
Prevention of delayed neuronal death in gerbil hippocampus by ion channel blockers.
Topics: Animals; Azepines; Brain Ischemia; Calcium Channel Blockers; Gerbillinae; Glutamates; Hippocampus; Ion Channels; Male; Neurons; Oxazoles; Oxazolidinones; Piperazines; Time Factors | 1988 |
Mechanism of action of DuP 721: inhibition of an early event during initiation of protein synthesis.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Bacterial Proteins; Cell-Free System; Chemical Phenomena; Chemistry; DNA, Bacterial; Escherichia coli; Oxazoles; Oxazolidinones; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; RNA, Bacterial; Templates, Genetic | 1988 |
Enhancement of 5-HT-induced anorexia: a test of the reversibility of monoamine oxidase inhibitors.
Topics: Animals; Benzamides; Clorgyline; Drug Synergism; Feeding Behavior; Male; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Comparative in vitro activity of the new oxazolidinones DuP 721 and DuP 105 against staphylococci and streptococci.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Glycopeptides; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Streptococcus; Teicoplanin; Vancomycin | 1989 |
Comparative in-vitro activity of vancomycin, teicoplanin, ramoplanin (formerly A16686), paldimycin, DuP 721 and DuP 105 against methicillin and gentamicin resistant Staphylococcus aureus.
Topics: Acetylcysteine; Anti-Bacterial Agents; Culture Media; Depsipeptides; Disaccharides; Drug Resistance, Microbial; Gentamicins; Glycopeptides; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillin Resistance; Peptides, Cyclic; Staphylococcus aureus; Teicoplanin; Temperature; Vancomycin | 1989 |
[Comparison of the new MAO-A inhibitors moclobemide, brofaromine and toloxatone with tranylcypromine in an animal experiment: significance for clinical practice].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzamides; Blood Pressure; Heart Rate; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Tranylcypromine | 1989 |
[The subchronic toxicity of 5-vinyloxazolidine-2-thione in rats].
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drinking; Eating; Erythrocyte Count; Female; Leukocyte Count; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Plant Extracts; Rats; Sex Characteristics; Thymus Gland; Thyroid Gland | 1989 |
Depression of decerebrate rigidity in the rat by antagonists of excitatory amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Azepines; Blood Pressure; Decerebrate State; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Kynurenic Acid; Male; Muscle Relaxants, Central; Muscle Rigidity; Oxazoles; Oxazolidinones; Piperazines; Rats; Rats, Inbred Strains | 1989 |
Simple high-performance liquid chromatographic method for the measurement of toloxatone in rabbit cerebrospinal fluid and plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rabbits; Spectrophotometry, Ultraviolet | 1989 |
Variation in response of gram-positive cocci to the combination DuP 721 and ciprofloxacin.
Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1989 |
Inhibitory effects of a new, potent, centrally acting muscle relaxant, (4S,5R)-4-(2-methylpropyl)-3-[3-(perhydroazepin-1-yl)propyl]-5- phenyl-1,3-oxazolidin-2-one (NC-1200) on micturition contractions of the bladder in rats.
Topics: Animals; Azepines; Blood Pressure; Ganglia, Spinal; Male; Muscle Relaxants, Central; Muscle, Smooth; Neurons; Oxazoles; Oxazolidinones; Pressure; Rats; Rats, Inbred Strains; Synaptic Transmission; Urinary Bladder | 1988 |
A new class of potent centrally acting muscle relaxants: pharmacology of oxazolidinones in rat decerebrate rigidity.
Topics: Animals; Azepines; Decerebrate State; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Motor Endplate; Muscle Relaxants, Central; Muscle Rigidity; Neurons; Oxazoles; Oxazolidinones; Piperidines; Rats; Rats, Inbred Strains; Reflex; Tremor | 1986 |
[Proposal of a new analgesia test based on the observation of nociceptive behavior induced by electric stimulation of dental pulp in the rat].
Topics: Analgesia; Analgesics; Animals; Benzoxazoles; Dental Pulp; Electric Stimulation; Glafenine; Male; Morphine; Nociceptors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains | 1987 |
Direct determination of the enantiomeric purity of (5S)-3-isopropyl-5-p-toluenesulphonyloxymethyloxazolidin-2-one on a cellulose-based chiral stationary phase. In-process control of a chiral intermediate used in the synthesis of enantiomerically pure beta
Topics: Adrenergic beta-Antagonists; Chromatography, High Pressure Liquid; Indicators and Reagents; Oxazoles; Oxazolidinones; Spectrophotometry, Ultraviolet; Stereoisomerism | 1987 |
Inactivation of thymidylate synthase by chlorine disinfectants.
Topics: Calcium; Calcium Compounds; Disinfectants; Kinetics; Lacticaseibacillus casei; Oxazoles; Oxazolidinones; Sulfhydryl Reagents; Thymidylate Synthase | 1986 |
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. II. Biochemical characterization of monoamine oxidase inhibition.
Topics: Animals; Benzamides; Biogenic Amines; Brain; Clorgyline; Dopamine; Duodenum; Harmaline; Isoenzymes; Liver; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Pyridazines; Rats; Selegiline; Synaptosomes | 1987 |
R-goitrin- and BHA-induced modulation of aflatoxin B1 binding to DNA and biliary excretion of thiol conjugates in rats.
Topics: Aflatoxin B1; Aflatoxins; Amino Acids; Animals; Bile; Butylated Hydroxyanisole; Chromatography, High Pressure Liquid; Diet; DNA; Glutathione Transferase; Liver; Male; Mixed Function Oxygenases; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1987 |
In-vitro microbiological activities of DuP 105 and DuP 721, novel synthetic oxazolidinones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Candida albicans; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pseudomonas aeruginosa; Staphylococcus; Time Factors | 1988 |
Monoamine oxidase-B inhibition: a comparison of in vivo and ex vivo measures of reversible effects.
Topics: Animals; Drug Interactions; In Vitro Techniques; Male; Monoamine Oxidase; Motor Activity; Oxazoles; Oxazolidinones; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline; Time Factors | 1988 |
Potentiation of tyramine pressor responses in conscious rats by reversible inhibitors of monoamine oxidase.
Topics: Animals; Benzamides; Blood Pressure; Clorgyline; Drug Synergism; Male; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Tyramine | 1988 |
Inactivation of Giardia lamblia and Giardia canis cysts by combined and free chlorine.
Topics: Analysis of Variance; Animals; Chlorine; Disinfectants; Giardia; Hydrogen-Ion Concentration; Oxazoles; Oxazolidinones; Temperature; Water | 1988 |
Is free halogen necessary for disinfection?
Topics: Bromine; Chemical Phenomena; Chemistry; Chlorine; Disinfectants; Oxazoles; Oxazolidinones; Staphylococcus aureus | 1988 |
Pharmacological properties of a new centrally acting muscle relaxant (NC-1200) in isolated muscle preparations.
Topics: Animals; Aorta, Thoracic; Azepines; Bivalvia; Cecum; Female; Guinea Pigs; Ileum; In Vitro Techniques; Iris; Male; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Oxazoles; Oxazolidinones; Rabbits; Ranidae; Rats; Rats, Inbred Strains; Species Specificity; Stomach; Trachea; Uterus | 1988 |
In vitro evaluation of DuP 105 and DuP 721, two new oxazolidinone antimicrobial agents.
Topics: Ampicillin; Anti-Bacterial Agents; Cefaclor; Chemical Phenomena; Chemistry; Ciprofloxacin; Erythromycin; Gram-Positive Bacteria; Oxazoles; Oxazolidinones; Vancomycin | 1988 |
In vitro activities of two oxazolidinone antimicrobial agents, DuP 721 and DuP 105.
Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1988 |
Activity and mechanism of action of DuP 105 and DuP 721, new oxazolidinone compounds.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Norfloxacin; Oxazoles; Oxazolidinones; Ribosomal Proteins; Staphylococcus; Streptococcus; Time Factors | 1988 |
Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Female; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1987 |
Inactivation of Legionella pneumophila by hypochlorite and an organic chloramine.
Topics: Calcium; Calcium Compounds; Disinfectants; Hydrogen-Ion Concentration; Legionella; Oxazoles; Oxazolidinones; Temperature; Time Factors; Water Microbiology; Water Supply | 1987 |
Bactericidal properties of an organic N-chloramine formed in situ.
Topics: Chemical Phenomena; Chemistry; Disinfectants; Hydrogen-Ion Concentration; Oxazoles; Oxazolidinones; Staphylococcus aureus; Temperature | 1987 |
[Humoryl].
Topics: Depressive Disorder; Humans; Oxazoles; Oxazolidinones | 1986 |
Studies of monoamine oxidase and semicarbazide-sensitive amine oxidase. I. Inhibition by a selective monoamine oxidase-B inhibitor, MD 780236.
Topics: Animals; In Vitro Techniques; Kinetics; Lung; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Semicarbazides; Testis | 1986 |
Influence of selective, reversible inhibitors of monoamine oxidase on the prolonged depletion of striatal dopamine by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Harmaline; Homovanillic Acid; Male; Mice; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Oxidation-Reduction; Pyridines | 1985 |
Effects of dietary R-goitrin on hepatic and intestinal glutathione S-transferase, microsomal epoxide hydratase and ethoxycoumarin O-deethylase activities in the rat.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Body Weight; Diet; Epoxide Hydrolases; Feeding Behavior; Glutathione Transferase; Intestine, Small; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Oxygenases; Rats; Rats, Inbred Strains | 1985 |
Bactericidal properties of a new water disinfectant.
Topics: Bacteria; Calcium; Calcium Compounds; Disinfectants; Hydrogen-Ion Concentration; Oxazoles; Oxazolidinones; Pseudomonas aeruginosa; Shigella boydii; Staphylococcus aureus; Structure-Activity Relationship | 1985 |
MD 240928 and harmaline: opposite selectivity in antagonism of the inactivation of types A and B monoamine oxidase by pargyline in mice.
Topics: Alkaloids; Animals; Brain; Harmaline; Isoenzymes; Liver; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Pargyline; Time Factors | 1986 |
Formation of a complex between the analgesic, 6-benzoyl-benzoxazolidinone (CERM 10194), and beta-cyclodextrin.
Topics: Analgesics; Benzoxazoles; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cyclodextrins; Dextrins; Oxazoles; Oxazolidinones; Starch | 1985 |
On the reversibility of reversible MAO inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Brain; Clorgyline; Dopamine; Female; Homovanillic Acid; Kinetics; Liver; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1985 |
[Urovalidin Bracco in the therapy of urinary tract infections in children].
Topics: Anesthetics, Local; Anti-Infective Agents, Urinary; Cycloserine; Drug Combinations; Drug Evaluation; Humans; Isoxazoles; Oxazoles; Oxazolidinones; Phenazopyridine; Pyridines; Urinary Tract Infections | 1973 |
Inhibition of monoamine oxidase by 3-amino-2-oxazolidinone and 2-hydroxy-ethylhydrazine.
Topics: Amines; Animals; Brain; Hydrazines; Injections, Intraperitoneal; Ketones; Liver; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Time Factors; Tissue Extracts | 1971 |
In vivo effect of amiodarone, thiocyanate, perchlorate and goitrin on thyroxine deiodination in rat liver.
Topics: Amiodarone; Animals; Benzofurans; Diiodothyronines; Iodine; Liver; Male; Oxazoles; Oxazolidinones; Perchlorates; Rats; Rats, Inbred Strains; Thiocyanates; Thyroxine; Triiodothyronine | 1984 |
Some biochemical aspects of the potential benefit of associating MD780515 with tricyclic antidepressants.
Topics: Amphetamine; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Tyramine | 1981 |
Neuropharmacological profile of MD 780515, a new reversible inhibitor of type A monoamine oxidase.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Central Nervous System; Central Nervous System Stimulants; Drug Interactions; Female; Hypnotics and Sedatives; Macaca mulatta; Male; Mice; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains | 1982 |
Different stereoselective inhibition of monoamine oxidase-B by the R- and S-enantiomers of MD 780236.
Topics: Animals; Biotransformation; Brain; In Vitro Techniques; Isomerism; Liver; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains | 1983 |
A monoamine oxidase-B inhibitor, MD 780236, metabolized essentially by the A form of the enzyme in the rat.
Topics: Animals; Brain; Clorgyline; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Metabolism of the monoamine oxidase-B inhibitor, MD 780236 and its enantiomers by the A and B forms of the enzyme in the rat.
Topics: Animals; Biotransformation; Brain; Clorgyline; In Vitro Techniques; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Stereoisomerism | 1983 |
Inhibition of semicarbazide-sensitive amine oxidase by monoamine oxidase B inhibitors from the oxazolidinone series.
Topics: Animals; Clonidine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Semicarbazides | 1984 |
Studies on the naturally occurring goitrogen 5-vinyl-2-thiooxazolidone. Metabolism and antithyroid effect in the rat.
Topics: Animals; Antithyroid Agents; Brassica; Dose-Response Relationship, Drug; Female; Organ Size; Oxazoles; Oxazolidinones; Rats; Seeds; Thyroid Gland; Time Factors; Tissue Distribution | 1980 |
The identification of the goitrogen (-)5-vinyloxazolidine-2-thione (goitrin), as a bitter principle of cooked brussels sprouts (Brassica oleracea L. var. gemmifera).
Topics: Antithyroid Agents; Hot Temperature; Oxazoles; Oxazolidinones; Plants; Vegetables | 1981 |
Hepatic effects of R-goitrin in Sprague-Dawley rats.
Topics: Animals; Antithyroid Agents; Ascorbic Acid; Blood Chemical Analysis; Dimethyl Sulfoxide; Drinking; Female; Kidney; Liver; Male; Mitogens; Organ Size; Oxazoles; Oxazolidinones; Propylene Glycols; Rats; Rats, Inbred Strains; Thyroid Gland | 1982 |
Plasma protein binding of the reversible type A MAO inhibitor cimoxatone (MD 780515).
Topics: Bilirubin; Blood Proteins; gamma-Globulins; Humans; Lipoproteins; Monoamine Oxidase Inhibitors; Orosomucoid; Oxazoles; Oxazolidinones; Serum Albumin; Tryptophan | 1983 |
Biochemical changes in layer and broiler chickens when fed on a high-glucosinolate rapeseed meal.
Topics: Alkaline Phosphatase; Animals; Antithyroid Agents; Aspartate Aminotransferases; Brassica; Chickens; Diet; Female; L-Lactate Dehydrogenase; Liver; Male; Oxazoles; Oxazolidinones; Plant Poisoning; Poultry Diseases | 1983 |
The formation of the acidic and alcoholic metabolites of MD 780236.
Topics: Acids; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcohols; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Biotransformation; Brain; Cattle; Horses; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Oxazoles; Oxazolidinones; Oxidation-Reduction | 1984 |
The metabolism of dopamine by both forms of monoamine oxidase in the rat brain and its inhibition by cimoxatone.
Topics: Aging; Animals; Brain; Clorgyline; Dopamine; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Species Specificity | 1983 |
Partial or total protection from long-acting monoamine oxidase inhibitors (MAOIs) by new short-acting MAOIs of type A MD780515 and type B MD780236.
Topics: Animals; Brain; Clorgyline; Dose-Response Relationship, Drug; Female; Liver; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Selegiline; Tranylcypromine | 1983 |
[Comparison of the diagnostic indices in poultry treated against fowl typhoid pullorum].
Topics: Animal Feed; Animals; Chickens; Chronic Disease; Female; Furazolidone; Liver; Lung; Myocardium; Nitrofurans; Oxazoles; Oxazolidinones; Poultry Diseases; Salmonella Infections, Animal; Spectinomycin | 1980 |
Measurement of tyramine in human plasma, utilising ion-pair extraction and high-performance liquid chromatography with amperometric detection.
Topics: Allylamine; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrodes; Humans; Indicators and Reagents; Oxazoles; Oxazolidinones; Tyramine | 1984 |
Polymorphism of the analgesic 6-benzoylbenzoxazolidinone (CERM 10194).
Topics: Analgesics; Benzoxazoles; Chemical Phenomena; Chemistry, Physical; Crystallization; Oxazoles; Oxazolidinones | 1984 |
Reversed-phase high-performance liquid chromatographic separation of 14C-labelled toloxatone and its metabolites.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Oxazoles; Oxazolidinones | 1984 |
Oral absorption and concentration-effect relationship of tyramine with and without cimoxatone, a type-A specific inhibitor of monoamine oxidase.
Topics: Absorption; Administration, Oral; Biological Availability; Blood Pressure; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Heart Rate; Humans; Male; Norepinephrine; Oxazoles; Oxazolidinones; Tyramine | 1983 |
The deamination of noradrenaline and 5-hydroxytryptamine by rat brain and heart monoamine oxidase and their inhibition by cimoxatone, toloxatone and MD 770222.
Topics: Animals; Brain; Deamination; In Vitro Techniques; Kinetics; Male; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Nerve Tissue Proteins; Norepinephrine; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Serotonin | 1983 |
High-performance liquid chromatographic determination of cimoxatone and its O-demethyl metabolite in plasma.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Kinetics; Oxazoles; Oxazolidinones | 1983 |
Pharmacokinetic and relative bioavailability studies of cimoxatone in humans.
Topics: Adolescent; Adult; Biological Availability; Humans; Kinetics; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Solubility | 1984 |
Goitrin--a nitrosatable constitutent of plant foodstuffs.
Topics: Biotransformation; Brassica; Mutagenicity Tests; Nitroso Compounds; Oxazoles; Oxazolidinones | 1984 |
Monoamine oxidase inhibitors and histamine metabolism.
Topics: Animals; Clorgyline; Histamine; Iproniazid; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Selegiline; Tranylcypromine | 1980 |
Properties of a new chloramine disinfectant and detoxicant.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Chickens; Disinfectants; Hydrogen-Ion Concentration; Oxazoles; Oxazolidinones; Water | 1982 |
Cimoxatone is a reversible tight-binding inhibitor of the A form of rat brain monoamine oxidase.
Topics: Animals; Brain; Clorgyline; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains | 1983 |
Intestinal metabolism of tyramine by both forms of monoamine oxidase in the rat.
Topics: Animals; Brain; Clorgyline; Hydrogen-Ion Concentration; In Vitro Techniques; Intestines; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Inbred Strains; Tyramine | 1983 |
The enzyme-activated irreversible inhibition of type-B monoamine oxidase by 3-(4-[(3-chlorophenyl)methoxy]phenyl)-5-[(methylamino) methyl]-2-oxazolidinone methanesulphonate (compound MD 780236) and the enzyme-catalysed oxidation of this compound as compet
Topics: Animals; Hydrogen Peroxide; In Vitro Techniques; Isoenzymes; Kinetics; Male; Mitochondria, Liver; Models, Biological; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Oxidation-Reduction; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1983 |
Neurochemical effects in vitro and in vivo of the antidepressant Ro 11-1163, a specific and short-acting MAO-A inhibitor.
Topics: Animals; Antidepressive Agents; Benzamides; Benzeneacetamides; Brain; Catecholamines; Hypothalamus; Injections, Intraventricular; Male; Microsomes, Liver; Moclobemide; Monoamine Oxidase Inhibitors; Oxazines; Oxazoles; Oxazolidinones; Rats; Time Factors | 1983 |
Gas--liquid chromatographic determination of toloxatone in human plasma. Routine analysis of a wide range of drug concentrations using a nitrogen-selective detector.
Topics: Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Kinetics; Oxazoles; Oxazolidinones; Statistics as Topic | 1983 |
Comparative effects of semisynthetic D-5-vinyl-2-thiooxazolidone and water-extracted rapeseed meal in the rat.
Topics: Animals; Brassica; Diet; Female; Liver; Male; Organ Size; Oxazoles; Oxazolidinones; Plant Proteins; Rats; Thyroid Gland | 1982 |
Determination of oxazolidine-2-thiones in biological fluids in the ppb range.
Topics: Animal Feed; Animals; Benzoates; Cattle; Chromatography, Gas; Goats; Microchemistry; Milk; Oxazoles; Oxazolidinones | 1982 |
Pharmacokinetics of toloxatone in man following intravenous and oral administrations.
Topics: Administration, Oral; Adult; Antidepressive Agents; Biological Availability; Female; Humans; Infusions, Parenteral; Kinetics; Male; Oxazoles; Oxazolidinones; Protein Binding; Serum Albumin | 1982 |
Characteristics of the inhibition of rat brain monoamine oxidase in vitro by MD780515.
Topics: Animals; Brain; Harmaline; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Rats; Serotonin | 1981 |
Antagonism between long acting monoamine oxidase inhibitors (MAOI) and MD780515, a new specific and reversible MAOI.
Topics: Animals; Brain; Clorgyline; Drug Interactions; Liver; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Oxazolidinones; Rats; Serotonin; Time Factors; Tranylcypromine | 1980 |
Degradation of glucosinolates during in vitro incubations of rapeseed meal with myrosinase (EC 3.2.3.1) and with pepsin (EC 3.4.23.1)-hydrochloric acid, and contents of porcine small intestine and caecum.
Topics: Animals; Antithyroid Agents; Brassica; Digestion; Food Additives; Gastrointestinal Contents; Glucosinolates; Glycoside Hydrolases; In Vitro Techniques; Methylene Chloride; Oxazoles; Oxazolidinones; Pepsin A; Swine; Time Factors | 1994 |
Modulation of glutathione S-transferase activity and isozyme pattern in liver and small intestine of rats fed goitrin- and T3-supplemented diets.
Topics: Animals; Antithyroid Agents; Chromatography, High Pressure Liquid; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Food, Fortified; Glutathione; Glutathione Disulfide; Glutathione Transferase; Intestine, Small; Isoenzymes; Liver; Male; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Selenium; Thyrotropin; Thyroxine; Triiodothyronine | 1995 |
Formation of chloroethylamine and 1,3-oxazolidine-2-one following ifosfamide administration in humans.
Topics: Ethylamines; Humans; Ifosfamide; Oxazoles; Oxazolidinones | 1995 |
Effects of glucosinolate breakdown products on the hepatic biotransformation system in male rats.
Topics: Alkenes; Animals; Antithyroid Agents; Biotransformation; Cytochrome P-450 Enzyme System; Cytosol; Glucosinolates; Glutathione Transferase; Isothiocyanates; Liver; Male; Microsomes, Liver; Nitriles; Organ Size; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Thiocyanates | 1993 |
Reversible and selective inhibitors of monoamine oxidase A in mental and other disorders.
Topics: Alzheimer Disease; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Benzamides; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Panic Disorder; Phobic Disorders; Piperidines | 1995 |
Binding mode of phospholipase A2 with a new type of phospholipid analog having an oxazolidinone ring.
Topics: Animals; Calcium; Cattle; Crotalid Venoms; Elapid Venoms; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Structure; Organophosphorus Compounds; Oxazoles; Oxazolidinones; Phospholipases A; Phospholipases A2; Substrate Specificity | 1995 |
Application of pharmacokinetic studies to a novel antidepressant, E2011.
Topics: Animals; Antidepressive Agents; Benzothiazoles; Biotransformation; Chromatography, High Pressure Liquid; Dogs; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles | 1994 |
The oxazolidinedione CP-92,768-2 partially protects insulin receptor substrate-1 from dexamethasone down-regulation in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Benzofurans; Dexamethasone; Down-Regulation; Gene Expression Regulation; Insulin; Insulin Receptor Substrate Proteins; Mice; Mifepristone; Oxazoles; Oxazolidinones; Phosphoenolpyruvate Carboxykinase (GTP); Phosphoproteins; Receptors, Glucocorticoid; RNA, Messenger | 1995 |
Life-threatening pseudophaeochromocytoma after toloxatone, terbutaline, and phenylephrine.
Topics: Adrenal Gland Neoplasms; Aged; Catecholamines; Diagnosis, Differential; Drug Interactions; Female; Humans; Hypertension; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenylephrine; Pheochromocytoma; Terbutaline; Vasoconstriction | 1993 |
The determination of cyclophosphamide and its metabolites in blood plasma as stable trifluoroacetyl derivatives by electron capture chemical ionization gas chromatography/mass spectrometry.
Topics: Antineoplastic Agents; Cyclophosphamide; Gas Chromatography-Mass Spectrometry; Humans; Neoplasms; Nitrogen Mustard Compounds; Oxazoles; Oxazolidinones; Phosphoramide Mustards | 1994 |
Transformation of heterocyclic reversible monoamine oxidase-B inactivators into irreversible inactivators by N-methylation.
Topics: Animals; Binding Sites; Cattle; Enzyme Activation; Enzyme Reactivators; Furans; Kinetics; Liver; Methylation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Pyrrolidinones; Structure-Activity Relationship | 1993 |
(4S,5S)-4-methyl-5-phenyl-1,3-oxazolidin-2-one.
Topics: Crystallography; Models, Molecular; Molecular Conformation; Oxazoles; Oxazolidinones; Pyridines; Stereoisomerism; Tosyl Compounds | 1993 |
Minor and clinically non-significant interaction between toloxatone and amitriptyline.
Topics: Adult; Aged; Amitriptyline; Depression; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenotype; Reproducibility of Results | 1993 |
New phospholipase A2 inhibitor: synthesis and inhibition mechanism of oxazolidinone phospholipid analog.
Topics: Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Organophosphorus Compounds; Oxazoles; Oxazolidinones; Phospholipases A; Phospholipases A2; Snake Venoms | 1995 |
Preparation and biological activity of 24-epi-26,26,26,27,27,27-hexafluoro- 1 alpha,25-dihydroxyvitamin D2.
Topics: Animals; Binding Sites; Bone Density; Calcitriol; Calcium; Chick Embryo; Cytosol; Femur; Magnetic Resonance Spectroscopy; Male; Organ Size; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Vitamin D Deficiency | 1995 |
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.
Topics: Acetamides; Animals; Anti-Infective Agents; Dogs; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Linezolid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats | 1996 |
Dose proportionality studies of novel thiazolidinedione derivatives as potent antidiabetic agents in mice.
Topics: Animals; Benzofurans; Chromatography, High Pressure Liquid; Half-Life; Hypoglycemic Agents; Male; Mice; Mice, Inbred Strains; Naphthalenes; Oxazoles; Oxazolidinones; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidinediones | 1995 |
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Injections, Intravenous; Injections, Subcutaneous; Linezolid; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin | 1996 |
E2011 a novel, selective and reversible inhibitor of monoamine oxidase type A.
Topics: Animals; Benzothiazoles; Brain; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Serotonin; Thiazoles | 1996 |
Extending therapeutic options? Prospects for the future.
Topics: Cerebrovascular Circulation; Forecasting; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
311C90 (Zolmitriptan), a novel centrally and peripheral acting oral 5-hydroxytryptamine-1D agonist: a comparison of its absorption during a migraine attack and in a migraine-free period.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1996 |
In vitro activities in new oxazolidinone antimicrobial agents against enterococci.
Topics: Acetamides; Anti-Bacterial Agents; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1996 |
Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci.
Topics: Acetamides; Amino Acid Sequence; Anti-Bacterial Agents; Cephalosporins; Linezolid; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazoles; Oxazolidinones; Penicillin Resistance; Streptococcus pneumoniae; Virginiamycin | 1996 |
In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; beta-Lactam Resistance; Ceftriaxone; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillins; Streptococcus pneumoniae | 1996 |
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin | 1996 |
Transport of the antibacterial agent oxazolidin-2-one and derivatives across intestinal (Caco-2) and renal (MDCK) epithelial cell lines.
Topics: Animals; Anti-Infective Agents; Caco-2 Cells; Cell Line; Chromatography, High Pressure Liquid; Dogs; Epithelial Cells; Epithelium; Humans; Intestinal Mucosa; Kidney; Models, Molecular; Oxazoles; Oxazolidinones; Spectrophotometry, Ultraviolet | 1996 |
In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinones.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Diffusion; Gram-Negative Bacteria; Gram-Positive Cocci; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1996 |
In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Nafcillin; Oxazoles; Oxazolidinones; Penicillins; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin | 1996 |
In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Synergism; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Naphthyridines; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Virginiamycin | 1996 |
Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine?
Topics: Animals; Brain Stem; Cats; Cranial Sinuses; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; Injections, Intravenous; Migraine Disorders; Neural Inhibition; Neurons; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1996 |
In vitro activities of the oxazolidinone antibiotics U-100592 and U-100766 against Staphylococcus aureus and coagulase-negative Staphylococcus species.
Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Colony Count, Microbial; Linezolid; Oxazoles; Oxazolidinones; Staphylococcus; Staphylococcus aureus | 1997 |
311C90: patient profiles and typical case histories of migraine management.
Topics: Adult; Female; Humans; Male; Menstruation; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
The prevalence and possible causes of bound and extractable residues of the furazolidone metabolite 3-amino-2-oxazolidinone in porcine tissues.
Topics: Animal Feed; Animals; Anti-Infective Agents; Drug Residues; Food Contamination; Furazolidone; Housing, Animal; Kidney; Liver; Meat; Muscle, Skeletal; Oxazoles; Oxazolidinones; Swine | 1997 |
Determination of the furazolidone metabolite, 3-amino-2-oxazolidinone, in porcine tissues using liquid chromatography-thermospray mass spectrometry and the occurrence of residues in pigs produced in Northern Ireland.
Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Drug Residues; Drug Stability; Food Contamination; Furazolidone; Liver; Mass Spectrometry; Muscles; Northern Ireland; Oxazoles; Oxazolidinones; Sensitivity and Specificity; Swine | 1997 |
Possible therapeutic effect of T-794, a novel reversible inhibitor of monoamine oxidase-A, on post-stroke emotional disturbances, assessed in animal models of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Depression; Disease Models, Animal; Emotions; Ischemic Attack, Transient; Male; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Naphthalenes; Oxazoles; Oxazolidinones; Rats; Reserpine | 1997 |
Quality control guidelines for amoxicillin, amoxicillin-clavulanate, azithromycin, piperacillin-tazobactam, roxithromycin, ticarcillin, ticarcillin-clavulanate, trovafloxacin (CP 99,219), U-100592, and U-100766 for various National Committee for Clinical
Topics: Acetamides; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Azithromycin; Clavulanic Acids; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Naphthyridines; Oxazoles; Oxazolidinones; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality Control; Roxithromycin; Ticarcillin | 1996 |
Receptor specificity and trigemino-vascular inhibitory actions of a novel 5-HT1B/1D receptor partial agonist, 311C90 (zolmitriptan).
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Humans; Male; Muscle Contraction; Oxazoles; Oxazolidinones; Rabbits; Serotonin Receptor Agonists; Trigeminal Ganglion; Tryptamines | 1997 |
Direct evidence for central sites of action of zolmitriptan (311C90): an autoradiographic study in cat.
Topics: Animals; Autoradiography; Brain Stem; Cats; Central Nervous System; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Spinal Cord; Tryptamines | 1997 |
Is a central action of acute antimigraine drugs essential?
Topics: Analgesics; Animals; Brain; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Measuring central action of acute antimigraine drugs in humans.
Topics: Analgesics; Brain; Contingent Negative Variation; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Visual; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Would any acute treatment for migraine demonstrate recurrence?
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
Stereoselective determination of a new antidepressant, E2011, and its diastereoisomer as a metabolite by high-performance liquid chromatography.
Topics: Animals; Antidepressive Agents; Benzothiazoles; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles | 1997 |
Effects of newly developed excitatory amino acid antagonists on vestibular type I neurons in the cat.
Topics: Animals; Azepines; Cats; Decerebrate State; Dose-Response Relationship, Drug; Electrodes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Injections, Intravenous; Iontophoresis; Kainic Acid; Muscle Relaxants, Central; N-Methylaspartate; Neuromuscular Junction; Neurons; Neurotransmitter Agents; Oxazoles; Oxazolidinones; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Rotation; Vestibular Nerve; Vestibular Nuclei | 1997 |
Central effects of (5RS, 1'SR)-5-benzyl-3-(3'-morpholino-1'-phenylpropyl)-1,3-oxazolidin-2 -one monofumarate on the function of the bladder and periurethral skeletal muscle in anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Injections, Intravenous; Morpholines; Muscle Relaxants, Central; Muscle, Skeletal; Neuromuscular Junction; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Sympathetic Nervous System; Synaptic Transmission; Urinary Bladder | 1997 |
The bioavailability of residues of the furazolidone metabolite 3-amino-2-oxazolidinone in porcine tissues and the effect of cooking upon residue concentrations.
Topics: Animals; Biological Availability; Female; Furazolidone; Hot Temperature; Kidney; Liver; Meat; Muscles; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Swine | 1997 |
The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin.
Topics: Acetamides; Anti-Bacterial Agents; Chloramphenicol; Escherichia coli; Kinetics; Lincomycin; Oxazoles; Oxazolidinones; Puromycin; Ribosomes | 1997 |
Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Coliphages; Culture Media; Escherichia coli; Linezolid; Microbial Sensitivity Tests; N-Formylmethionine; Oxazoles; Oxazolidinones; Poly U; Polyribosomes; Protein Biosynthesis; Ribosomes; Transcription, Genetic | 1997 |
Central sites of actions of zolmitriptan and sumatriptan: 5HT1B, 5HT1D and 5HT1F receptor distribution.
Topics: Central Nervous System; Humans; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
Absorption, distribution, metabolism and excretion of a new, 14C-labelled oxazolidinone MAO-A inhibitor in rat and dog.
Topics: Absorption; Animals; Benzothiazoles; Biliary Tract; Blood Proteins; Carbon Radioisotopes; Dogs; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Protein Binding; Rats; Rats, Sprague-Dawley; Thiazoles; Tissue Distribution | 1997 |
Identification of the metabolites of a new oxazolidinone MAO-A inhibitor in rat.
Topics: Animals; Benzothiazoles; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Methylation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Thiazoles | 1997 |
Attacking migraine headache from beginning to end.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The clinical pharmacokinetics of zolmitriptan.
Topics: Absorption; Adult; Case-Control Studies; Female; Humans; Liver Diseases; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 1997 |
Disk diffusion test interpretive criteria and quality control recommendations for testing linezolid (U-100766) and eperezolid (U-100592) with commercially prepared reagents.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Evaluation Studies as Topic; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indicators and Reagents; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Quality Control | 1997 |
Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat.
Topics: Afferent Pathways; Animals; Cats; Electric Stimulation; Homocysteine; Humans; Iontophoresis; Neurons; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Spinal Cord; Sumatriptan; Trigeminal Nerve; Tryptamines | 1997 |
Zolmitriptan receives migraine indication.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Oral migraine treatment approved.
Topics: Administration, Oral; Contraindications; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Rabies Vaccines; Serotonin Receptor Agonists; Tryptamines; United States; United States Food and Drug Administration | 1998 |
A triptan too far?
Topics: Acute Disease; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Pharmacological analysis of the haemodynamic effects of 5-HT1B/D receptor agonists in the normotensive rat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Drug Interactions; Heart Rate; Hemodynamics; Male; Oxazoles; Oxazolidinones; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 1998 |
In vivo characterization of T-794, a novel reversible inhibitor of monoamine oxidase-A, as an antidepressant with a wide safety margin.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Pressure; Levodopa; Male; Mice; Monoamine Oxidase Inhibitors; Naphthalenes; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Tyramine | 1998 |
Zolmitriptan for migraine.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Cortical spreading depression-associated hyperemia in rats: involvement of serotonin.
Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Hyperemia; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 1998 |
Comparison of more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat.
Topics: Animals; Cats; Cerebrovascular Circulation; Cranial Sinuses; Electric Stimulation; Gene Expression Regulation; Genes, fos; Migraine Disorders; Neurons, Afferent; Nociceptors; Oxazoles; Oxazolidinones; Pain; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission; Trigeminal Caudal Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal; Tryptamines; Vasoconstrictor Agents | 1998 |
Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Ente
Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Enterococcus faecalis; Enterococcus faecium; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin | 1998 |
On the target of a novel class of antibiotics, oxazolidinones, active against multidrug-resistant Gram-positive bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple; Escherichia coli; Oxazoles; Oxazolidinones; Protein Biosynthesis; RNA, Messenger; Staphylococcus | 1998 |
Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay.
Topics: Acetamides; Anti-Bacterial Agents; Cell-Free System; Mutation; Oxazoles; Oxazolidinones; Protein Biosynthesis; Ribosomes; Staphylococcus aureus; Transcription, Genetic | 1998 |
Species differences and mechanism of the epimerization of a new MAO-A inhibitor.
Topics: Administration, Oral; Animals; Benzothiazoles; Dogs; Guinea Pigs; Haplorhini; Isomerism; Mice; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Species Specificity; Thiazoles | 1998 |
It never hurts to check. Taking the time to read a label benefited this migraine sufferer.
Topics: Adult; Contraindications; Drug Labeling; Female; Humans; Medication Errors; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Education as Topic; Reading; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Effects of sumatriptan on coronary flow and left ventricular function in the isolated perfused guinea pig heart.
Topics: Animals; Coronary Circulation; Diastole; Dihydroergotamine; Endothelium, Vascular; Guinea Pigs; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxazoles; Oxazolidinones; Perfusion; Piperazines; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Ventricular Function, Left | 1998 |
Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring.
Topics: Acetamides; Anti-Bacterial Agents; Caco-2 Cells; Enterococcus faecalis; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Permeability; Piperazines; Pyridines; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Structure-Activity Relationship; Triazenes | 1998 |
Effects of the serotonin1B/1D receptor agonist zolmitriptan on motor cortical excitability in humans.
Topics: Adult; Brain; Electromyography; Female; Humans; Male; Motor Cortex; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
New "triptans" and other drugs for migraine.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents | 1998 |
The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Escherichia coli; Linezolid; Oxazoles; Oxazolidinones; Peptide Initiation Factors; Protein Synthesis Inhibitors; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer, Met; Staphylococcus aureus | 1998 |
Cranial vascular effects of zolmitriptan, a centrally active 5-HT1B/1D receptor partial agonist for the acute treatment of migraine.
Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Carotid Arteries; Cats; Cerebral Cortex; Disease Models, Animal; Dogs; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
The effects of 5-HT1A, 5-HT1B and 5-HT1D receptor agonists on trigeminal nociceptive neurotransmission in anaesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analgesics; Animals; Electric Stimulation; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1998 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
A triptan too far?
Topics: Headache; Humans; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
[Zolmitriptan].
Topics: Chemistry, Pharmaceutical; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Headache after frequent use of serotonin agonists zolmitriptan and naratriptan.
Topics: Adult; Female; Headache; Humans; Indoles; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Tryptamines | 1999 |
The in-vitro activity of linezolid (U-100766) and tentative breakpoints.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Colony Count, Microbial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Time Factors | 1998 |
A novel antimicrobial agent joins the battle against resistant bacteria.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Oxazoles; Oxazolidinones | 1999 |
Therapeutic agent for treating dysuria (NC-1800): absolute configuration of the enantiomers.
Topics: Animals; Crystallography, X-Ray; In Vitro Techniques; Molecular Conformation; Morpholines; Muscle Relaxants, Central; Muscle, Skeletal; Oxazoles; Oxazolidinones; Rats; Stereoisomerism; Urinary Bladder; Urination Disorders | 1999 |
Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors.
Topics: Animals; Binding, Competitive; Cell Line; Cold Temperature; COS Cells; HeLa Cells; Humans; Indoles; Kinetics; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Sumatriptan; Triazoles; Tritium; Tryptamines | 1999 |
Successful treatment of persistent vancomycin-resistant Enterococcus faecium bacteremia with linezolid and gentamicin.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus faecium; Female; Gentamicins; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin | 1999 |
Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Antitubercular Agents; Female; Linezolid; Mice; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Tuberculosis | 1999 |
Comparative in-vitro activities of moxifloxacin, trovafloxacin, quinupristin/dalfopristin and linezolid against staphylococci.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Fluoroquinolones; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Oxazoles; Oxazolidinones; Quinolines; Staphylococcal Infections; Staphylococcus; Virginiamycin | 1999 |
In vitro activity of linezolid against vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillin Resistance; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Vancomycin | 1999 |
Susceptibility testing of linezolid by two standard methods.
Topics: Acetamides; Anti-Bacterial Agents; Enterococcus faecalis; Enterococcus faecium; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Sensitivity and Specificity; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes | 1999 |
Effect of acute ethanol administration on toloxatone pharmacokinetics in rabbits.
Topics: Animals; Cross-Over Studies; Drug Interactions; Ethanol; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rabbits; Random Allocation | 1999 |
Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cardiovascular System; Coronary Vessels; Dose-Response Relationship, Drug; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Ketanserin; Methiothepin; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tissue Distribution; Tryptamines; Vasoconstriction | 1999 |
Zolmitriptan.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Partial agonism at serotonin 5-HT1B and dopamine D2L receptors using a luciferase reporter gene assay.
Topics: Animals; CHO Cells; Cricetinae; Cyclic AMP; Dihydroergotoxine; Dopamine Agonists; Genes, Reporter; Lisuride; Luciferases; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptors, Dopamine D2; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin; Serotonin Receptor Agonists; Tryptamines | 1999 |
In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae.
Topics: Acetamides; Acute Disease; Anti-Bacterial Agents; Child; Clindamycin; Drug Resistance, Microbial; Erythromycin; Humans; Linezolid; Microbial Sensitivity Tests; Otitis Media; Oxazoles; Oxazolidinones; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae | 1999 |
In vitro activities of five new antimicrobial agents against Brucella melitensis.
Topics: Acetamides; Anti-Bacterial Agents; Brucella melitensis; Humans; Linezolid; Microbial Sensitivity Tests; Mupirocin; Oxazoles; Oxazolidinones; Rifabutin; Virginiamycin | 1999 |
Drug-induced headaches.
Topics: Analgesics, Non-Narcotic; Ergotamine; Headache; Humans; Indoles; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
In vitro activities of linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococci.
Topics: Acetamides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enterococcus; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Streptococcus; Teicoplanin; Vancomycin | 1999 |
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to the novel oxazolidinones eperezolid (PNU-100592) and linezolid (PNU-100766)
Topics: Acetamides; Anti-Bacterial Agents; Bordetella; Bordetella pertussis; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 1999 |
Toxicological response of rats to a novel monoamine oxidase type-A inhibitor, (5R)-3-[2-((1S)-3-cyano-1-hydroxypropyl)benzothiazol-6-yl]-5- methoxymethyl-2-oxazolidinone (E2011), orally administered for 13 weeks.
Topics: Administration, Oral; Animals; Benzothiazoles; Body Weight; Eating; Female; Glutathione S-Transferase pi; Glutathione Transferase; Harderian Gland; Hematologic Tests; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Monoamine Oxidase Inhibitors; Organ Size; Oxazoles; Oxazolidinones; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Salivation; Thiazoles | 1999 |
Synthesis of optically active NC-1800, a therapeutic agent for urinary disturbance.
Topics: Indicators and Reagents; Morpholines; Muscle Relaxants, Central; Oxazoles; Oxazolidinones; Oxidation-Reduction; Stereoisomerism; Urologic Diseases | 1999 |
[A new antibacterial agent can stop resistance development. Expectations are connected to linezolid, an oxazolidinone with a new pharmacological action].
Topics: Acetamides; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Linezolid; Oxazoles; Oxazolidinones | 1999 |
Efficacy of 5HT in migraine.
Topics: Action Potentials; Animals; Cats; Cranial Sinuses; Electric Stimulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 1999 |
Methicillin-resistant Staphylococcus aureus infection in a renal allograft recipient treated successfully with a novel new antimicrobial agent (linezolid): new treatment options for infections due to resistant organisms.
Topics: Acetamides; Adult; Anti-Infective Agents; Drug Resistance, Microbial; Humans; Kidney Transplantation; Linezolid; Male; Methicillin Resistance; Oxazoles; Oxazolidinones; Staphylococcal Infections; Transplantation, Homologous | 1999 |
Measuring event-related potentials.
Topics: Adult; Arousal; Contingent Negative Variation; Dexfenfluramine; Event-Related Potentials, P300; Evoked Potentials, Auditory, Brain Stem; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1999 |
Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptan.
Topics: Cimetidine; Clorgyline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Isoenzymes; Ketoconazole; Liver; Male; Microsomes, Liver; Omeprazole; Oxazoles; Oxazolidinones; Recombinant Proteins; Serotonin Receptor Agonists; Theophylline; Tryptamines | 1999 |
Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.
Topics: Acetamides; Binding Sites; Drug Resistance, Microbial; Halobacterium salinarum; Linezolid; Mutation; Nucleic Acid Conformation; Oxazoles; Oxazolidinones; Peptide Chain Initiation, Translational; Peptidyl Transferases; Protein Synthesis Inhibitors; Ribosomes; RNA, Ribosomal, 23S; RNA, Transfer, Met | 1999 |
Battling drug resistance.
Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Oxazoles; Oxazolidinones; Streptococcal Infections; Streptococcus pyogenes; Vancomycin Resistance; Virginiamycin | 1999 |
Activities of the oxazolidinones linezolid and eperezolid in experimental intra-abdominal abscess due to Enterococcus faecalis or vancomycin-resistant Enterococcus faecium.
Topics: Abdominal Abscess; Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Linezolid; Male; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vancomycin | 1999 |
[Antibiosis. Therapeutic strategies in intensive care].
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Critical Care; Drug Therapy; Gram-Positive Bacterial Infections; Humans; Linezolid; Needs Assessment; Oxazoles; Oxazolidinones | 1999 |
[Differentiated therapy of migraine attack].
Topics: Adult; Analgesics; Antiemetics; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Treatment Outcome; Tryptamines | 1999 |
Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Bufotenin; Chromatography, High Pressure Liquid; Humans; Indoles; Mass Spectrometry; Migraine Disorders; Molecular Structure; Oxazoles; Oxazolidinones; Piperidines; Sensitivity and Specificity; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Activity of linezolid against multi-resistant gram-positive bacteria from diverse hospitals in the United Kingdom.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Multiple; Enterococcus; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Streptococcus; Streptococcus pneumoniae; United Kingdom | 2000 |
Serotonin 5HT1B/1D receptor agonists abolish NMDA receptor-evoked enhancement of nitric oxide synthase activity and cGMP concentration in brain cortex slices.
Topics: Animals; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Nitric Oxide Synthase; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Auditory evoked potentials in the assessment of central nervous system effects of antimigraine drugs.
Topics: Adolescent; Adult; Cerebral Cortex; Evoked Potentials, Auditory; Female; Humans; Indoles; Male; Oxazoles; Oxazolidinones; Piperidines; Reproducibility of Results; Sample Size; Serotonin Receptor Agonists; Tryptamines | 1999 |
Successful treatment of vancomycin-resistant Enterococcus faecium bacteremia with linezolid after failure of treatment with synercid (quinupristin/dalfopristin).
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Bone Marrow Transplantation; Drug Administration Schedule; Drug Therapy, Combination; Enterococcus faecium; Follow-Up Studies; Gram-Positive Bacterial Infections; Humans; Leukemia, Myeloid, Acute; Linezolid; Male; Middle Aged; Oxazoles; Oxazolidinones; Postoperative Complications; Treatment Failure; Treatment Outcome; Vancomycin Resistance; Virginiamycin | 2000 |
Efficacy of linezolid in experimental otitis media.
Topics: Acetamides; Amoxicillin; Animals; Anti-Bacterial Agents; Chinchilla; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Haemophilus Infections; Haemophilus influenzae; Humans; Linezolid; Otitis Media; Oxazoles; Oxazolidinones; Pneumococcal Infections; Streptococcus pneumoniae | 2000 |
Determination of linezolid in plasma by reversed-phase high-performance liquid chromatography.
Topics: Acetamides; Animals; Anti-Infective Agents; Calibration; Chromatography, High Pressure Liquid; Dogs; Indicators and Reagents; Linezolid; Mice; Oxazoles; Oxazolidinones; Quality Control; Rabbits; Rats; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1999 |
In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against Staphylococci and Enterococci, including vancomycin- intermediate and -resistant strains.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Time Factors; Vancomycin; Virginiamycin | 2000 |
Spinal cord infarction during use of zolmitriptan: a case report.
Topics: Female; Humans; Infarction; Menstruation; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Spinal Cord; Tryptamines | 2000 |
MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animals.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Horses; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rhodococcus equi | 2000 |
Drug information incorrect.
Topics: Canada; Contraindications; Drug Interactions; France; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Tryptamines; Vasodilator Agents | 2000 |
FDA approves first drug in new class of antibiotics.
Topics: Anti-Infective Agents; Bacterial Infections; Drug Approval; Humans; Oxazoles; Oxazolidinones; United States; United States Food and Drug Administration | 2000 |
Total synthesis of (+)-laurencin: an asymmetric alkylation-ring-closing metathesis approach to medium ring ethers.
Topics: Aldehydes; Alkylation; Ethers; Ethers, Cyclic; Magnetic Resonance Spectroscopy; Oxazoles; Oxazolidinones; Oxocins; Spectrophotometry, Infrared; Stereoisomerism | 1999 |
Activity of linezolid against Gram-positive cocci possessing genes conferring resistance to protein synthesis inhibitors.
Topics: Acetamides; Drug Resistance, Microbial; Gram-Positive Cocci; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Protein Synthesis Inhibitors; Ribosomes | 2000 |
Zolmitriptan stimulates a Ca(2+)-dependent K(+) current in C6 glioma cells stably expressing recombinant human 5-HT(1B) receptors.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Humans; Membrane Potentials; Oxadiazoles; Oxazoles; Oxazolidinones; Peptides; Piperazines; Potassium Channels; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Serotonin Antagonists; Serotonin Receptor Agonists; Tetraethylammonium; Tryptamines; Tumor Cells, Cultured | 2000 |
Comparative in vitro activities of linezolid, quinupristin-dalfopristin, moxifloxacin, and trovafloxacin against erythromycin-susceptible and -resistant streptococci.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Microbial; Drug Therapy, Combination; Erythromycin; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Oxazoles; Oxazolidinones; Quinolines; Streptococcus; Virginiamycin | 2000 |
In vitro activities of linezolid alone and in combination with amoxicillin, clarithromycin, and metronidazole against Helicobacter pylori.
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Synergism; Drug Therapy, Combination; Helicobacter pylori; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillins | 2000 |
Linezolid (Zyvox).
Topics: Acetamides; Administration, Oral; Anti-Infective Agents; Controlled Clinical Trials as Topic; Costs and Cost Analysis; Dose-Response Relationship, Drug; Drug Interactions; Humans; Infusions, Parenteral; Linezolid; Oxazoles; Oxazolidinones; Protein Synthesis Inhibitors | 2000 |
Linezolid approval brings new treatment option for resistant bacteria.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Infections; Drug Interactions; Drug Resistance, Microbial; Humans; Linezolid; Oxazoles; Oxazolidinones | 2000 |
Zolmitriptan reverses blink reflex changes induced during the migraine attack in humans.
Topics: Adolescent; Adult; Blinking; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Ganglion; Tryptamines; Vasoconstrictor Agents | 2000 |
Triptans to the rescue: effective therapy for migraine headaches in the workplace.
Topics: Absenteeism; Adult; Cost-Benefit Analysis; Efficiency; Female; Humans; Indoles; Injections, Subcutaneous; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Self Administration; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Workplace | 2000 |
Oxidation of the novel oxazolidinone antibiotic linezolid in human liver microsomes.
Topics: Acetamides; Animals; Anti-Infective Agents; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Humans; Linezolid; Mass Spectrometry; Microsomes; Microsomes, Liver; Oxazoles; Oxazolidinones; Oxidation-Reduction | 2000 |
Treatment of a vancomycin-resistant Enterococcus faecium ventricular drain infection with quinupristin/dalfopristin and review of the literature.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Enterococcus faecium; Fatal Outcome; Female; Gram-Positive Bacterial Infections; Humans; Hydrocephalus; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Linezolid; Middle Aged; Oxazoles; Oxazolidinones; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Vancomycin; Ventriculoperitoneal Shunt; Virginiamycin | 2000 |
Antibiotic available for compassionate use.
Topics: Acetamides; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Hotlines; Humans; Linezolid; Methicillin Resistance; Oxazoles; Oxazolidinones; Staphylococcal Infections | 1998 |
Novel piperidinyloxy oxazolidinone antimicrobial agents.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Piperidines; Staphylococcus aureus | 2001 |
Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Translocation; Escherichia coli; Kinetics; Linezolid; Oxazoles; Oxazolidinones; Peptide Chain Initiation, Translational; Peptide Elongation Factor G; Peptide Elongation Factors; Peptidyl Transferases; Protein Biosynthesis; Ribosomes; RNA, Transfer, Met | 2002 |
In vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus | 2002 |
New C(19)-diterpenoid alkaloids from the roots of Delphinium potaninii var. jiufengshanense.
Topics: Alkaloids; Amides; Delphinium; Diterpenes; Magnetic Resonance Spectroscopy; Oxazoles; Oxazolidinones; Plant Roots | 2002 |
Plant-derived biomolecules in fermented cabbage.
Topics: Brassica; Chromatography, High Pressure Liquid; Fermentation; Flavonoids; Food Handling; Gas Chromatography-Mass Spectrometry; Glucosinolates; Hydrogen-Ion Concentration; Indoles; Isothiocyanates; Kaempferols; Nitrates; Nitriles; Nitrites; Oxazoles; Oxazolidinones | 2002 |
Synthesis and antibacterial activity of oxazolidinone containing sulphonyl group.
Topics: Acetamides; Anti-Infective Agents; Bacteria; Chemical Phenomena; Chemistry, Physical; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Structure-Activity Relationship; Sulfonamides | 2003 |
Goitrin from fresh cabbage.
Topics: Antithyroid Agents; Brassica; Brassicaceae; Humans; Oxazoles; Oxazolidinones; Vegetables | 1959 |
[5-Morpholinomethyl-3-amino-2-oxazolidinone derivatives with hypotensive activity].
Topics: Antidepressive Agents; Morpholines; Oxazoles; Oxazolidinones | 1962 |
[Furan derivatives of 3-amino-2-oxazolidinone].
Topics: Furans; Oxazoles; Oxazolidinones | 1962 |
SYNERGISM OF D-4-AMINO-3-ISOXAZOLIDONE AND O-CARBAMYL-D-SERINE.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Isoxazoles; Mycobacterium; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Pharmacology; Research; Serine; Staphylococcus | 1964 |
[PHARMACOLOGIC ACTION OF 5-THIOPHENYLAMETHYLENE-2-OXAZOLIDONE (5-TFO) ON ARTERIAL PRESSURE].
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Oxazoles; Oxazolidinones; Pharmacology; Rats; Research | 1964 |
BEHAVIORAL STIMULANTS. 4-OXAZOLIDINONES.
Topics: Animals; Behavior, Animal; Central Nervous System Agents; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Haplorhini; Oxazoles; Oxazolidinones; Pharmacology; Rats; Research | 1965 |
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION.
Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines | 1965 |
SOLUBILIZATION AND EVALUATION OF POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE BARBITURATE SYSTEMS.
Topics: Barbiturates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Oxazoles; Oxazolidinones; Phenobarbital; Povidone; Research; Solubility | 1965 |
MYROSINASE ACTIVITY IN BACTERIA AS DEMONSTRATED BY THE CONVERSION OF PROGOITRIN TO GOITRIN.
Topics: Bacteria; Enterobacteriaceae; Glucosinolates; Glycoside Hydrolases; Hydrolases; Intestines; Metabolism; Oxazoles; Oxazolidinones; Research | 1965 |
[5-ARYLOXY-2-OXAZOLIDINONES: SYNTHESIS AND ACTIVITY ON THE CENTRAL NERVOUS SYSTEM].
Topics: Central Nervous System; Mice; Oxazoles; Oxazolidinones; Pharmacology; Research; Toxicology | 1965 |
Linezolid compared with eperezolid, vancomycin, and gentamicin in an in vitro model of antimicrobial lock therapy for Staphylococcus epidermidis central venous catheter-related biofilm infections.
Topics: Acetamides; Anti-Infective Agents; Biofilms; Catheterization, Central Venous; Catheters, Indwelling; Colony Count, Microbial; Gentamicins; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Sodium Chloride; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin | 2003 |
Asymmetric synthesis of (4R,5R)-cytoxazone and (4R,5S)-epi-cytoxazone.
Topics: Cyclization; Heterocyclic Compounds, 2-Ring; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Oxazoles; Oxazolidinones; Oxidation-Reduction; Stereoisomerism | 2004 |
beta-Pseudopeptide foldamers. The homo-oligomers of (4R)-(2-oxo-1,3-oxazolidin-4-yl)-acetic acid (D-Oxac).
Topics: Amino Acids; Magnetic Resonance Spectroscopy; Molecular Structure; Monte Carlo Method; Oligopeptides; Oxazoles; Oxazolidinones; Protein Structure, Secondary; Solvents | 2004 |
Novel tetrahydro-thieno pyridyl oxazolidinone: an antibacterial agent.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pyridines; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin | 2004 |
In vitro metabolism of a new oxazolidinedione hypoglycemic agent utilizing liver microsomes and recombinant human cytochrome P450 enzymes.
Topics: Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Dogs; Humans; Hydroxylation; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxazoles; Oxazolidinones; PPAR alpha; Rats; Recombinant Proteins | 2005 |
Activity of RBx 7644 and RBx 8700, new investigational oxazolidinones, against Mycobacterium tuberculosis infected murine macrophages.
Topics: Acetamides; Animals; Antitubercular Agents; Cell Line; Drug Antagonism; Furans; Isoniazid; Linezolid; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Rifampin | 2005 |
Synthesis and antibacterial activity of novel (un)substituted benzotriazolyl oxazolidinone derivatives.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Structure-Activity Relationship; Vancomycin | 2005 |
Synthesis and antibacterial activity of dihydro-1,2-oxazine and 2-pyrazoline oxazolidinones: novel analogs of linezolid.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Linezolid; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones | 2005 |
Synthesis and SAR of novel oxazolidinones: discovery of ranbezolid.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Furans; Gram-Positive Bacteria; Heterocyclic Compounds; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcal Infections; Structure-Activity Relationship | 2005 |
Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis.
Topics: Acetamides; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Flow Cytometry; Humans; In Vitro Techniques; K562 Cells; Linezolid; Mitochondria, Heart; Oxazoles; Oxazolidinones; Protein Synthesis Inhibitors; Rats; Structure-Activity Relationship | 2005 |
Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Bacterial; Drug Resistance, Microbial; Fluorine; Linezolid; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Oxazoles; Oxazolidinones; Structure-Activity Relationship | 2006 |
Ranbezolid, a novel oxazolidinone antibacterial: in vivo characterisation of monoamine oxidase inhibitory potential in conscious rats.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Blood Pressure; Clorgyline; Dose-Response Relationship, Drug; Furans; Linezolid; Male; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Wistar | 2006 |
In vitro activities of DA-7157 and DA-7218 against Mycobacterium tuberculosis and Nocardia brasiliensis.
Topics: Anti-Bacterial Agents; Humans; Microbial Sensitivity Tests; Mycetoma; Mycobacterium tuberculosis; Nocardia; Organophosphates; Oxazoles; Oxazolidinones; Prodrugs; Tetrazoles | 2006 |
In vitro activities of the novel oxazolidinones DA-7867 and DA-7157 against rapidly and slowly growing mycobacteria.
Topics: Anti-Bacterial Agents; Humans; In Vitro Techniques; Indicator Dilution Techniques; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium Complex; Mycobacterium chelonae; Mycobacterium fortuitum; Mycobacterium kansasii; Mycobacterium marinum; Oxazoles; Oxazolidinones; Tetrazoles | 2006 |
Reusable catalysts for the asymmetric Diels-Alder reaction.
Topics: Catalysis; Copper; Crystallography, X-Ray; Cyclopentanes; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Oxazoles; Oxazolidinones; Stereoisomerism | 2007 |
Pharmacokinetics of DA-7218, a new oxazolidinone, and its active metabolite, DA-7157, after intravenous and oral administration of DA-7218 and DA-7157 to rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Stability; Injections, Intravenous; Male; Organophosphates; Oxazoles; Oxazolidinones; Prodrugs; Protein Binding; Rats; Rats, Sprague-Dawley; Tetrazoles | 2007 |
Efficacy of DA-7218, a new oxazolidinone prodrug, in the treatment of experimental actinomycetoma produced by Nocardia brasiliensis.
Topics: Acetamides; Actinomycosis; Animals; Disease Models, Animal; Linezolid; Mice; Mice, Inbred BALB C; Mycetoma; Nocardia; Nocardia Infections; Organophosphates; Oxazoles; Oxazolidinones; Prodrugs; Tetrazoles; Treatment Outcome | 2008 |
[Some new antitubercular agents].
Topics: Acetamides; Antitubercular Agents; Diarylquinolines; Humans; Linezolid; Nitroimidazoles; Oxazoles; Oxazolidinones; Quinolines | 2008 |
Utilization of Bombyx mori larvae as a surrogate animal model for evaluation of the anti-infective potential of oxazolidinones.
Topics: Animals; Anti-Infective Agents; Bombyx; Disease Models, Animal; Furans; Humans; Larva; Methicillin Resistance; Mice; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2008 |
Effect of oxazolidinone, RBx 7644 (ranbezolid), on inhibition of staphylococcal adherence to plastic surfaces.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Dose-Response Relationship, Drug; Furans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Plastics; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin; Virginiamycin | 2008 |
Photooxygenation of 5-dialkylamino-4-pyrrolin-3-ones. Synthesis of highly functionalized ureas, 2-oxazolidinones, and 2-oxazolinones.
Topics: Acetates; Alkanes; Alkynes; Amidines; Amines; Catalysis; Cyclization; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Hydrogenation; Methanol; Models, Chemical; Oxazoles; Oxazolidinones; Oxygen; Photochemistry; Pyrroles; Solvents; Urea | 2008 |
Pyrazoline-based mycobactin analogues as MAO-inhibitors.
Topics: Acetamides; Animals; Binding Sites; Catalytic Domain; Drug Design; Humans; Inhibitory Concentration 50; Linezolid; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Pyrazoles; Rats; Siderophores | 2008 |
Mode of action of Ranbezolid against staphylococci and structural modeling studies of its interaction with ribosomes.
Topics: Acetamides; Anti-Bacterial Agents; Cell Membrane Permeability; Furans; Linezolid; Oxazoles; Oxazolidinones; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomes; Staphylococcus aureus; Staphylococcus epidermidis; Transcription, Genetic | 2009 |
Synthesis and biological activity of novel oxazolidinones.
Topics: Anti-Bacterial Agents; Bacteria; Drug Design; Furans; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin Resistance | 2009 |
Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges.
Topics: Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Enterococcaceae; Gram-Positive Bacteria; History, Medieval; In Vitro Techniques; Indicator Dilution Techniques; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbiological Techniques; Organophosphates; Oxazoles; Oxazolidinones; Quality Control; Streptococcus; Tetrazoles | 2010 |
In vivo pharmacodynamics of torezolid phosphate (TR-701), a new oxazolidinone antibiotic, against methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains in a mouse thigh infection model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Female; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Serum; Staphylococcal Infections; Staphylococcus aureus; Tetrazoles; Thigh | 2011 |
Enantioselective α-arylation of carbonyls via Cu(I)-bisoxazoline catalysis.
Topics: Catalysis; Copper; Hydrocarbons, Aromatic; Lactones; Oxazoles; Oxazolidinones; Stereoisomerism | 2011 |
Impact of granulocytes on the antimicrobial effect of tedizolid in a mouse thigh infection model.
Topics: Animals; Anti-Infective Agents; Female; Granulocytes; Mice; Microbial Sensitivity Tests; Models, Theoretical; Organophosphates; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Tetrazoles; Thigh | 2011 |
Identification, preparation and UHPLC determination of process-related impurity in zolmitriptan.
Topics: Chemistry Techniques, Synthetic; Chromatography, High Pressure Liquid; Drug Contamination; Limit of Detection; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxazoles; Oxazolidinones; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tryptamines | 2012 |
Activity of tedizolid phosphate (TR-701) in murine models of infection with penicillin-resistant and penicillin-sensitive Streptococcus pneumoniae.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Culture Media; Drug Administration Schedule; Female; Linezolid; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Microbial Sensitivity Tests; Models, Animal; Organophosphates; Oxazoles; Oxazolidinones; Penicillin Resistance; Penicillins; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Survival Rate | 2012 |
Comparative pharmacodynamics of the new oxazolidinone tedizolid phosphate and linezolid in a neutropenic murine Staphylococcus aureus pneumonia model.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Blood Proteins; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Linezolid; Lung; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Organophosphates; Oxazoles; Oxazolidinones; Pneumonia, Staphylococcal; Prodrugs; Protein Binding; Staphylococcus aureus | 2012 |
Addition of cyclic ureas and 1-methyl-2-oxazolidone to pyridynes: a new approach to pyridodiazepines, pyridodiazocines, and pyridooxazepines.
Topics: Azepines; Azocines; Benzene Derivatives; Molecular Structure; Oxazepines; Oxazoles; Oxazolidinones; Pyridines; Urea | 2013 |
PARADIONE in epilepsy.
Topics: Anticonvulsants; Epilepsy; Oxazoles; Oxazolidinones | 1950 |
Antimicrobial properties of furoxone, N-(5-nitro-2-furfurylidene-3-amino-2-oxazolidone).
Topics: Anti-Infective Agents; Furans; Furazolidone; Oxazoles; Oxazolidinones | 1953 |
Oxazolidinone derivatives: cytoxazone-linezolid hybrids induces apoptosis and senescence in DU145 prostate cancer cells.
Topics: Acetamides; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cellular Senescence; Humans; Linezolid; Male; Membrane Potential, Mitochondrial; Oxazoles; Oxazolidinones; Prostatic Neoplasms | 2014 |
New antibiotics for skin and skin-structure infections.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Linezolid; Male; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial | 2014 |
In vitro antimicrobial activity of the novel oxazolidinone tedizolid and comparator agents against Staphylococcus aureus and linezolid-resistant Gram-positive pathogens: a multicentre study in China.
Topics: Acetamides; China; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Staphylococcus aureus | 2014 |
Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Clindamycin; Diterpenes; Drug Resistance, Multiple, Bacterial; Gene Transfer Techniques; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Sequence Data; New York; Organophosphates; Oxazoles; Oxazolidinones; Plasmids; Staphylococcal Infections; Thiamphenicol | 2014 |
Tedizolid population pharmacokinetics, exposure response, and target attainment.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Female; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Neutrophils; Organophosphates; Oxazoles; Oxazolidinones; Platelet Count; Prodrugs; Skin Diseases, Bacterial; Staphylococcal Infections; Tetrazoles; Young Adult | 2014 |
Use of linezolid susceptibility test results as a surrogate for the susceptibility of Gram-positive pathogens to tedizolid, a novel oxazolidinone.
Topics: Acetamides; Anti-Bacterial Agents; Biomarkers; Diagnostic Errors; Gram-Positive Bacteria; Humans; Linezolid; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones | 2014 |
Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.
Topics: Acetamides; Anti-Bacterial Agents; Epidemiological Monitoring; Europe; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Organophosphates; Oxazoles; Oxazolidinones; Ribosomal Proteins; RNA, Ribosomal, 23S; United States | 2015 |
A closer inspection of tedizolid.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Male; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial | 2015 |
A closer inspection of tedizolid.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Male; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial | 2015 |
A closer inspection of tedizolid - authors' reply.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Male; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial | 2015 |
Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies.
Topics: Acetamides; Animals; Anti-Infective Agents; Bacteria; Biological Availability; Drug Design; Ether-A-Go-Go Potassium Channels; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Models, Molecular; Oxazoles; Oxazolidinones; Potassium Channel Blockers; Staphylococcal Infections; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2015 |
Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis.
Topics: Animals; Antitubercular Agents; Bacterial Load; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Linezolid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Organophosphates; Oxazoles; Oxazolidinones; Pyrazinamide; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |
A highly sensitive and efficient UPLC-MS/MS assay for rapid analysis of tedizolid (a novel oxazolidinone antibiotic) in plasma sample.
Topics: Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Female; Limit of Detection; Liquid-Liquid Extraction; Organophosphates; Oxazoles; Oxazolidinones; Rats, Wistar; Tandem Mass Spectrometry | 2016 |
Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
Topics: Administration, Intranasal; Adolescent; Adult; Body Weight; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Young Adult | 2017 |
Safety and Tolerability of More than Six Days of Tedizolid Treatment.
Topics: Anti-Bacterial Agents; Humans; Organophosphates; Oxazoles; Oxazolidinones; Retrospective Studies; Skin Diseases, Bacterial; Tetrazoles | 2020 |
Pharmacokinetics of tedizolid, sutezolid, and sutezolid-M1 in non-human primates.
Topics: Animals; Anti-Bacterial Agents; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Primates; Tetrazoles | 2020 |
[Pharmacological action and clinical effect of tedizolid phosphate (SIVEXTRO
Topics: Anti-Bacterial Agents; Humans; Japan; Methicillin-Resistant Staphylococcus aureus; Organophosphates; Oxazoles; Oxazolidinones; Staphylococcus aureus; Tablets | 2020 |
Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage.
Topics: Anti-Bacterial Agents; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mutation; Organophosphates; Oxazoles; Oxazolidinones; Serial Passage; Tetrazoles | 2021 |
Stereoselective Synthesis of Oxazolidin-2-Ones via an Asymmetric Aldol/Curtius Reaction: Concise Total Synthesis of (-)-Cytoxazone.
Topics: Aldehydes; Drug Discovery; Oxazoles; Oxazolidinones; Stereoisomerism | 2021 |
Efficacy and safety of tedizolid in a patient with linezolid-induced neutropenia: A case report.
Topics: Anti-Bacterial Agents; Humans; Linezolid; Microbial Sensitivity Tests; Neutropenia; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; Tetrazoles | 2021 |
A pharmacokinetic-pharmacodynamic (PKPD) model-based analysis of tedizolid against enterococci using the hollow-fibre infection model.
Topics: Animals; Anti-Bacterial Agents; Enterococcus; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Oxazolidinones; Tetrazoles | 2022 |