oxazoles has been researched along with opc-67683 in 203 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 9 (4.43) | 29.6817 |
2010's | 141 (69.46) | 24.3611 |
2020's | 53 (26.11) | 2.80 |
Authors | Studies |
---|---|
Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H | 1 |
Crismale, C; Saliu, OY; Schwander, SK; Wallis, RS | 1 |
Zhang, Y | 1 |
Kobayashi, K; Okada, M | 1 |
Barry, CE; Dowd, CS; Goodwin, MB; Keller, TH; Knox, JE; Li, X; Lipinski, CA; Manjunatha, UH | 1 |
Nau, JY | 2 |
Mancera, RL; Rivers, EC | 1 |
Budha, NR; Carson, EI; Cho, SH; Franzblau, SG; Hurdle, JG; Lee, RB; Lee, RE; Lenaerts, AJ; McNeil, MR; Meibohm, B; Qi, J; Scherman, MS | 1 |
Dawson, R; Diacon, AH; Donald, PR; Geiter, LJ; Hanekom, M; Hittel, N; Narunsky, K; Paccaly, AJ; Venter, A; Wells, CD | 1 |
Barry, CE; Boshoff, HI; Cherian, J; Dick, T; Dowd, CS; Gurumurthy, M; Lee, YS; Manjunatha, UH; Mukherjee, T; Nayyar, A; Niyomrattanakit, P; Singh, R; Tay, JA | 1 |
Awad, M; Cabrera-Rivero, JL; Chang, J; Danilovits, M; Gao, M; Geiter, LJ; Gler, MT; Koh, WJ; Kurve, A; Ogata, H; Park, SK; Sanchez-Garavito, E; Seaworth, B; Shim, TS; Skripconoka, V; Suh, GY; Suzuki, K; Tupasi, T; Vargas-Vasquez, DE; Wells, CD; Xiao, H | 1 |
Chaisson, RE; Nuermberger, EL | 1 |
Crunkhorn, S | 1 |
Cirule, A; Danilovits, M; Geiter, LJ; Kummik, T; Kurve, A; Leimane, V; Levina, K; Manissero, D; Pehme, L; Skenders, G; Skripconoka, V; Tomson, T; Wells, CD | 1 |
Schaberg, T | 1 |
Liu, Y; Sha, W; Tang, S; Xiao, H; Zhang, Q | 1 |
Boechat, N; Branco, FS; Pinto, AC | 1 |
Balasegaram, M; Brigden, G; du Cros, P; Horsburgh, CR; Hughes, J; McIlleron, H; Mitnick, CD; Nuermberger, E; Nyang'wa, BT; Phillips, PP; Rich, M; Varaine, F | 1 |
Burki, T | 1 |
Jeong, BH; Koh, WJ; Kwon, YS | 2 |
Blasi, F; Caminero Luna, J; Centis, R; D'Ambrosio, L; Dara, M; Esposito, S; Marais, B; Matteelli, A; Migliori, GB; Schaaf, HS; Tadolini, M | 1 |
Lo, JH; Ryan, NJ | 1 |
Cho, S; Franzblau, SG; Kim, Y; Lu, Y; Ma, Z; Mdluli, K; Upton, AM; Wang, B; Wang, Y; Xu, J; Yang, TJ | 1 |
Amoabeng, O; Mdluli, KE; Minkowski, A; Nuermberger, EL; Tasneen, R; Upton, AM; Williams, K | 1 |
Mizuno, K; Sasahara, K; Shimokawa, Y; Umehara, K; Yoda, N | 1 |
Blair, HA; Scott, LJ | 1 |
Chang, KC; Heyckendorf, J; Lange, C; Olaru, ID; von Groote-Bidlingmaier, F; Yew, WW | 1 |
Centis, R; D'ambrosio, L; Migliori, GB; Sotgiu, G | 1 |
Gruber, K | 1 |
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G | 1 |
Lynch, JB; Szumowski, JD | 1 |
Geiter, LJ; Gupta, R; Hittel, N; Wells, CD | 1 |
Abubakar, I; Brown, NM; Burman, WJ; Ellington, MJ; Feuerriegel, S; Ismail, NA; Javid, B; Köser, CU; Liddell, K; Moore, D; Niemann, S; Peacock, SJ; Török, ME | 1 |
Chopra, S; Dasgupta, A; Soni, I; Thakare, R | 1 |
Blaser, A; Denny, WA; Franzblau, SG; Kmentova, I; Ma, Z; Palmer, BD; Sutherland, HS; Thompson, AM; Wan, B; Wang, Y | 1 |
Cox, H; Daniels, C; Furin, J; Lessem, E; McKenna, L; Mitnick, CD; Mosidi, T; Reed, C; Seaworth, B; Stillo, J; Tisile, P; von Delft, D | 1 |
Diel, R; Hittel, N; Schaberg, T | 1 |
Bloemberg, GV; Böttger, EC; Hömke, R; Keller, PM; Ritter, C; Valsesia, G | 1 |
Hirao, Y; Kitano, K; Koyama, N; Sasahara, K; Shibata, M; Shimokawa, Y; Umehara, K | 1 |
Kitano, K; Koyama, N; Sasahara, K; Shibata, M; Shimokawa, Y; Umehara, K; Yoda, N | 1 |
Cirule, A; Gao, M; Geiter, LJ; Gupta, R; Wells, CD; Xiao, H | 1 |
Bianchini, S; Blasi, F; Esposito, S | 1 |
Brisson, J; Carter, S; Johnston, B; Meng, M; Roth, SE; Smith, B | 1 |
Caminero, JA; Scardigli, A | 1 |
Cox, H; Furin, J; Lessem, E; Mason, L; Reed, C; Seaworth, B | 1 |
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G; Spanevello, A | 1 |
Diel, R; Gibbert, J; Wirth, D; Wolfson, LJ | 1 |
Chopra, S; Dasgupta, A; De Groote, MA; Soni, I | 1 |
Bloemberg, GV; Borrell, S; Böttger, EC; Coscolla, M; Feldmann, J; Gagneux, S; Hömke, R; Keller, PM; Latshang, T; Ritter, C; Rothe, T; Schulthess, B; Stucki, D; Stuckia, D; Trauner, A | 1 |
Brigden, G; du Cros, P; Wong, S | 1 |
Bastard, M; Bonnet, M; du Cros, P; Hayrapetyan, A; Hewison, C; Khamraev, A; Khurkhumal, S; Kimenye, K; Sanchez-Padilla, E; Telnov, A; Themba, D; Varaine, F | 1 |
Dawson, A; Silva, DS; Upshur, RE | 1 |
Beckert, P; Hoffmann, H; Hofmann-Thiel, S; Jaton, K; Keller, PM; Kohl, TA; Merker, M; Nedialkova, L; Niemann, S; Rothe, T; Sahalchyk, E | 1 |
Brigden, G; Furin, J; Lessem, E; Lynch, S; Rich, M; Vaughan, L | 1 |
Ben Amor, Y; Sullivan, T | 1 |
Awad, M; Cabrera-Rivero, JL; Cirule, A; Danilovits, M; Gao, M; Geiter, LJ; Gentry, LM; Gupta, R; Sanchez-Garavito, E; Tupasi, T; Vargas-Vasquez, DE; Wells, CD; Xiao, H | 1 |
Fujiwara, M; Geiter, L; Kawasaki, M; Kreiswirth, BN; Kurepina, N; Liu, Y; Matsumoto, M; Shashkina, E; Stinson, K; Timm, J; Venter, A | 1 |
Hamasako, Y; Hashizume, K; Kashiyama, E; Ohzone, Y; Sasabe, H; Shibata, M; Shimokawa, Y; Umehara, K | 1 |
Battaglia, S; Borroni, E; Cabibbe, AM; Cirillo, DM; Hoffmann, H; Hofmann-Thiel, S; Merker, M; Nedialkova, L; Niemann, S; Schena, E; Trovato, A; Utpatel, C | 1 |
Auer, JL; Fairlamb, AH; Norval, S; Osuna-Cabello, M; Patterson, S; Read, KD; Simeons, FR; Stojanovski, L; Wyllie, S | 1 |
Furin, J; Master, I | 1 |
Centis, R; D'Ambrosio, L; Enwerem, M; Lingtsang, RD; Migliori, GB; Sadutshang, TD; Tadolini, M; Tiberi, S | 2 |
Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM | 1 |
Geiter, L; Mallikaarjun, S; Paccaly, A; Patil, S; Petersen, C; Shoaf, SE; Wells, C | 1 |
Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; Thee, S; van der Laan, L | 1 |
Byun, JH; Kang, HR; Lee, EK; Park, JA; Shin, JY | 1 |
Baudin, E; Cellamare, M; Mitnick, CD; Trippa, L; Ventz, S | 1 |
Dedicoat, M | 1 |
Akkerman, OW; Alffenaar, JC; Anthony, RM; Cobelens, FG; Grobusch, MP; Heysell, S; Tiberi, S; Van Soolingen, D | 1 |
Wallis, RS | 1 |
Centis, R; D'Ambrosio, L; Fuentes, Z; Migliori, GB; Sotgiu, G; Tiberi, S; Zumla, A | 1 |
Bauer, TT; Bettermann, G; Krieger, D; Mauch, H; Rüssmann, H; Schönfeld, N; Vesenbeckh, S | 1 |
Bianchini, S; Bosis, S; Esposito, S; Migliori, GB; Principi, N; Tadolini, M | 1 |
Hanaki, E; Hayashi, M; Matsumoto, M | 1 |
Gao, F; Hu, M; Zheng, C | 1 |
Cooke, G; Fortunak, J; Gotham, D; Hill, A; Khoo, S; Nytko, FE; Pozniak, A | 1 |
Centis, R; D'Ambrosio, L; Esposito, S; Migliori, GB; Pontali, E; Sotgiu, G; Tadolini, M; Tiberi, S | 1 |
Sharma, DC | 1 |
Brzezinski, A; Milstein, M; Mitnick, CD; Varaine, F | 1 |
Geiter, LJ; Gupta, R; Hafkin, J; Hittel, N; Wells, CD | 1 |
Dass, R; Hettle, R; Wirth, D | 1 |
Anderson, RF; Blaser, A; Chatelain, E; Denny, WA; Franzblau, SG; Launay, D; Ma, Z; Maes, L; Palmer, BD; Shinde, SS; Thompson, AM; Wan, B; Wang, Y | 1 |
Ahmed, Z; Bhagat, A; Kour, G; Singh, PP | 1 |
Dong, L; Fu, Y; Huang, H; Huo, F; Jing, W; Li, Y; Ma, Y; Pang, Y; Zhao, L; Zong, Z | 1 |
Gupta, R; Hafkin, J; Hittel, N; Martin, A | 2 |
Akkerman, O; Alffenaar, JW; Amale, R; Centis, R; D'Ambrosio, L; Ganatra, S; Maryandyshev, A; Migliori, GB; Mullerpattan, J; Pontali, E; Sadutshang, TD; Sotgiu, G; Tiberi, S; Topgyal, S; Udwadia, ZF | 1 |
Avaliani, Z; Ferlazzo, G; Hayrapetyan, A; Hewison, C; Jonckheere, S; Khaidarkhanova, Z; Lachenal, N; Mohr, E; Sinha, A; Skrahina, A; Vambe, D; Varaine, F; Vasilyeva, I | 1 |
Jo, KW; Nam, GB; Shim, TS; Yoon, HY | 1 |
Kabra, SK; Lodha, R; Mukherjee, A | 1 |
Chang, KC; Cox, H; Dheda, K; Esmail, A; Lange, C; Wasserman, S | 1 |
Cox, V; Furin, J; Lessem, E | 1 |
Dowdy, D; Merritt, MW; Taylor, H; von Delft, A; Zwerling, A | 1 |
Cox, H; Cox, V; Ditiu, L; Furin, J; Garcia-Prats, A; Koenig, S; Lessem, E; Nathavitharana, R; Reuter, A; Seddon, JA; Stillo, J; Tisile, P; von Delft, A; von Delft, D | 1 |
Hwang, SH; Jeon, D; Kang, B; Kang, H; Koh, WJ; Lee, T; Mok, J; Park, JS; Yim, JJ | 1 |
Barkane, L; Gupta, R; Hittel, N; Kuksa, L | 1 |
Aarti, C; Barbabosa-Pliego, A; Khusro, A; Salem, AZM | 1 |
Cox, V; Furin, J | 1 |
Barkane, L; Caumes, E; Fréchet-Jachym, M; Guglielmetti, L; Kuksa, L; Le Dû, D; Marigot-Outtandy, D; Robert, J; Veziris, N; Yazdanpanah, Y | 1 |
Akkerman, OW; Alffenaar, JW; Bolhuis, MS; de Lange, WCM; de Vries, G; de Zwaan, R; Dedicoat, M; Frijlink, HW; Gajraj, R; Grasmeijer, F; Hagedoorn, P; Kerstjens, HAM; Smith, G; van der Werf, TS; van Soolingen, D | 1 |
Migliori, GB; Tadolini, M; Tiberi, S | 1 |
Cox, H; De Avezedo, V; Egazaryan, L; Ferlazzo, G; Furin, J; Hewison, C; Hughes, J; Isaakidis, P; Jonckheere, S; Kalon, S; Khachatryan, N; Laxmeshwar, C; Mohr, E; Shroufi, A | 1 |
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Spanevello, A; Visca, D | 1 |
Fujiwara, M; Hariguchi, N; Kawasaki, M; Liu, Y; Matsumoto, M | 1 |
Hun Choe, Y; Kim, CT; Kim, HR; Kim, TO; Ko, YC; Kwon, YS; Shin, HJ | 1 |
Uplekar, M | 1 |
Brigden, G; Cox, V; Crespo, RH; Furin, J; Lessem, E; Lynch, S; Rich, ML; Waning, B | 1 |
Falzon, D; Halleux, CM; Jaramillo, E; Merle, C; Mirzayev, F; Olliaro, P; Weyer, K | 1 |
Hauser, J; Jaramillo, E; Kuwana, R; Masini, T; Nhat Linh, N | 1 |
Chang, KC; Chau, CH; Lam, FM; Law, WS; Lee, SN; Leung, CC; Leung, EC; Leung, WM; Mok, TY; Tai, LB; Yew, WW | 1 |
Ade, S; Alikhanova, N; Benedetti, G; Cox, H; Daniels, J; De Azevedo, V; Edwards, J; Ferlazzo, G; Furin, J; Hughes, J; Isaakidis, P; Kock, Y; Mohr, E; Reuter, A; Shroufi, A; Steele, SJ; Trivino Duran, L | 1 |
Arbex, MA; D'Ambrosio, L; Dalcolmo, M; Duarte, R; Gaga, M; Migliori, GB; Munoz-Torrico, M; Rendon, A; Silva, DR; Tiberi, S; Visca, D; Zumla, A | 1 |
Bothamley, G; Burman, M; Guglielmetti, L; Kunst, H; Lange, C; Tiberi, S; Togonidze, T; Wejse, C | 1 |
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G; Spanevello, A; Tadolini, M; Tiberi, S; Visca, D | 1 |
Borroni, E; Cirillo, DM; Crook, DW; Cugnata, F; Davies, TJ; Fowler, PW; Gibertoni Cruz, AL; Grazian, C; Hoosdally, SJ; Peto, TEA; Rancoita, PMV; Walker, TM | 1 |
Flexner, C; Moss, DM; Owen, A; Podany, AT; Rajoli, RKR; Siccardi, M; Swindells, S | 1 |
Choi, H; Kim, KJ; Lee, SH; Yang, JS | 1 |
Bamrah Morris, S; Goswami, ND; Khan, AN; Lardizabal, AA | 1 |
Loganathan, U; Mukhopadhyay, B; Purwantini, E | 1 |
Perdigão, J; Portugal, I | 1 |
Fan, Q; Ming, WK; Yip, WY; You, JHS | 1 |
Li, Y; Sun, F; Zhang, W | 1 |
Balanag, V; Bielskiene, V; Cadena, E; Caoili, J; Cirule, A; Danilovits, M; Davidaviciene, E; Domente, L; Geiter, LJ; Gupta, R; Hafkin, J; Hittel, N; Lizarbe, V; Patientia, R; Petersen, C; Sanchez, E; Segura, P; Staples, S; Ticona, E; Variava, E; von Groote-Bidlingmaier, F; Wells, C; Yu, C | 1 |
Centis, R; Migliori, GB; Sotgiu, G | 1 |
Okumura, M; Yoshiyama, T | 1 |
Ahn, H; Ahn, JH; Cho, SN; Hahn, S; Jang, JY; Jeon, D; Jhun, BW; Jo, KW; Kang, YA; Kim, CK; Kim, DK; Kim, JS; Kim, SY; Kim, YR; Koh, WJ; Lee, JH; Lee, JY; Lee, M; Lee, SH; Lee, T; Mok, J; Park, JS; Shim, TS; Shin, S; Shin, SJ; Song, T; Won, HJ; Yim, JJ | 1 |
Köser, CU; Kranzer, K; Maurer, FP | 1 |
Laughon, BE; Lee, SFK; Lipman, M; McHugh, TD | 1 |
Arora, VK; Chopra, KK | 1 |
Khalid, UK; Mathuria, KK; Munjal, SK; Myneedu, VP; Puri, MM; Sarin, R; Singla, N; Singla, R; Verma, A; Vohra, V | 1 |
Cox, H; Furin, J; Loveday, M; Reuter, A; Seddon, JA | 1 |
Hoffmann, H; Hofmann-Thiel, S; Kranzer, K; Krieger, D; Merker, M; Niemann, S; Polsfuss, S; Rüssmann, H; Schönfeld, N | 1 |
Akkerman, O; Al-Marzouqi, NH; Aleksa, A; Alffenaar, JW; Arias-Guillén, M; Belilovski, E; Bernal, E; Boeree, MJ; Borisov, SE; Bruchfeld, J; Cadiñanos Loidi, J; Cai, Q; Caminero, JA; Cebrian Gallardo, JJ; Centis, R; Codecasa, LR; D'Ambrosio, L; Dalcolmo, M; Danila, E; Dara, M; Davidavičienė, E; Davies Forsman, L; De Los Rios Jefe, J; Denholm, J; Duarte, R; Elamin, SE; Ferrarese, M; Filippov, A; Ganatra, S; Garcia, A; García-García, JM; Gayoso, R; Giraldo Montoya, AM; Gomez Rosso, RG; Gualano, G; Hoefsloot, W; Ilievska-Poposka, B; Jonsson, J; Khimova, E; Kuksa, L; Kunst, H; Laniado-Laborín, R; Li, Y; Magis-Escurra, C; Manfrin, V; Manga, S; Marchese, V; Martínez Robles, E; Maryandyshev, A; Matteelli, A; Migliori, GB; Mullerpattan, JB; Munoz-Torrico, M; Mustafa Hamdan, H; Nieto Marcos, M; Noordin, NM; Palmero, DJ; Palmieri, F; Payen, MC; Piubello, A; Pontali, E; Pontarelli, A; Quirós, S; Rendon, A; Skrahina, A; Šmite, A; Solovic, I; Sotgiu, G; Souleymane, MB; Spanevello, A; Stošić, M; Tadolini, M; Tiberi, S; Udwadia, ZF; van den Boom, M; Vescovo, M; Viggiani, P; Visca, D; Zhurkin, D; Zignol, M | 1 |
De Azevedo, V; Ferlazzo, G; Hewison, C; Isaakidis, P; Mohr, E | 1 |
Alffenaar, JC; Marais, BJ; Sintchenko, V | 1 |
Daley, CL; Huh, HJ; Jeon, K; Jhun, BW; Kim, DH; Kim, SY; Koh, WJ; Kwon, OJ; Lee, NY; Moon, SM; Shin, SJ | 1 |
Bethunaickan, R; Chandramohan, Y; Padmanaban, V; Ranganathan, UD; Swaminathan, S; Tripathy, S | 1 |
Jeon, D; Jhun, BW; Kang, B; Kang, H; Koh, WJ; Kwak, N; Lee, T; Mok, J; Yim, JJ | 1 |
Sharma, S | 1 |
Karekar, SR; Marathe, PA | 1 |
Chen, SH; Ding, CZ; Gao, C; Huang, ZG; Li, J; Liu, KL; Luo, W; Peng, CT; Tao, X; Yu, LT | 1 |
Ceyssens, PJ; Coppee, JY; Legendre, R; Mathys, V; Sismeiro, O; Sury, A; Van den Bossche, A; Varet, H | 1 |
Caoili, JC; Chawla, P; Dartois, V; Dooley, KE; Ganatra, S; Gler, MT; Jain, SK; Peloquin, CA; Pieterse, L; Ritchie, B; Tornheim, JA; Tucker, EW; Udwadia, ZF; Zimmerman, MD | 1 |
Atwood, S; Bastard, M; Franke, MF; Hewison, C; Huerga, H; Khan, AJ; Khan, PY; Khan, U; Mitnick, CD; Rich, M; Seung, KJ; Varaine, F | 1 |
Dheda, K; Dooley, KE; Furin, J; Gumbo, T; Maartens, G; Murray, M; Nardell, EA; Warren, RM | 1 |
Dheda, K; Esmail, A; Limberis, J; Olayanju, O | 1 |
Ahmed, S; Aiylchiev, S; Alam, M; Bastard, M; Docteur, W; Franke, MF; Gottlieb, G; Hewison, C; Huerga, H; Islam, S; Khachatryan, N; Khan, P; Khan, U; Kotrikadze, T; Kumsa, A; Lecca, L; Melikyan, N; Mitnick, CD; Naing, YY; Oyewusi, L; Putri, FA; Rich, M; Seung, KJ; Tassew, YM; Wanjala, S; Yedilbayev, A | 1 |
Avaliani, Z; Bablishvili, N; Barbakadze, K; Benkeser, D; Blumberg, HM; Kempker, RR; Kipiani, M; Mikiashvili, L; Peloquin, CA; Zhao, Y | 1 |
Kudoh, S; Kurashima, A; Ogata, H; Ohta, K; Okumura, M; Yoshimori, K; Yoshiyama, T | 1 |
Gandhi, S; Shah, I; Shetty, NS | 1 |
Afriat-Jurnou, L; Ahmed, FH; Almeida, DV; Aung, HL; Beatson, SA; Cook, GM; Forde, BM; Greening, C; Hards, K; Harold, LK; Jackson, CJ; Lee, BM; Mohamed, AE; Nuermberger, EL; Pidot, SJ; Stinear, TP; Taylor, MC; West, NP | 1 |
Farhat, M; Kadura, S; King, N; Köser, CU; Nakhoul, M; Theron, G; Zhu, H | 1 |
Jeon, D; Jo, KW; Kang, H; Shim, TS; Yim, JJ | 1 |
Alffenaar, JC; Anthony, RM; Bañuls, AL; Cao, TTH; Nguyen, NV; Nguyen, TVA; Nguyen, VAT; Vu, DH | 1 |
Jeon, D; Jo, KW; Kang, H; Lee, HH; Shim, TS; Yim, JJ | 1 |
Chander, J; Kaur, M; Mohan, N; Saini, V; Singhal, L | 1 |
Ader, F; Chiesi, S; Dominguez, J; Eimer, J; Guglielmetti, L; Masini, T; Robert, J; Varaine, F; Veziris, N | 1 |
Beko, B; Cox, H; Daniels, J; De Avezedo, V; Ferlazzo, G; Furin, J; Hughes, J; Isaakidis, P; Kock, Y; Makhanda, G; Mohr-Holland, E; Reuter, A; Trivino Duran, L | 1 |
Aono, A; Kato, S; Mitarai, S; Ohta, K; Okumura, M; Takaki, A; Yoshiyama, T | 1 |
Mathema, B; O'Donnell, M | 1 |
Avihingsanon, A; Borrell, S; Böttger, EC; Collantes, J; Egger, M; Fenner, L; Gagneux, S; Hömke, R; Keller, PM; Loiseau, C; Reichmuth, ML; Reinhard, M; Sander, P; Wilkinson, RJ; Yotebieng, M; Zürcher, K | 1 |
Alikhanova, N; Barbova, A; Battaglia, S; Cabibbe, AM; Cirillo, DM; Dean, AS; Groenheit, R; Ismail, N; Meehan, CJ; Mostofa Kamal, SM; Niemann, S; Rigouts, L; Skrahina, A; Spitaleri, A; Tahseen, S; Utpatel, C; Zignol, M | 1 |
Boyd, BJ; Clulow, AJ; Hawley, A; Pham, AC; Ramirez, G; Salim, M | 1 |
Bashiri, G; Ioerger, T; Lanoix, JP; Lee, J; Li, SY; Nuermberger, E; Rifat, D; Sacchettini, J; Shah, K | 1 |
Coutisson, S; Dalal, A; Das, M; Ferlazzo, G; Hossain, FN; Isaakidis, P; Kalon, S; Lachenal, N; Laxmeshwar, C; Mamnoon, F; Mansoor, H; Mathur, T; Meneguim, AC; Paryani, R; Ravi, S; Singh, P | 1 |
Jeon, D; Kang, H; Kwon, YS; Shim, TS; Yim, JJ | 1 |
Gibiansky, E; Mallikaarjun, S; Wang, X | 1 |
Breitscheidel, L; Ghosh, S; Hafkin, J; Hittel, N; Lazarevic, N; Martin, A | 1 |
Chopra, V; Gupta, A | 1 |
Al-Shaer, MH; Alghamdi, WA; Barbakadze, K; Kempker, RR; Kipiani, M; Mikiashvili, L; Peloquin, CA | 1 |
Auchynka, V; Charnysh, I; Hurevich, H; Katovich, D; Klimuk, D; Kumar, AMV; Sereda, Y; Setkina, S; Skrahin, A; Skrahina, A; Solodovnikova, V; Yedilbayev, A | 1 |
Auchynka, V; Hurevich, H; Katovich, D; Kumar, AMV; Sereda, Y; Setkina, S; Skrahin, A; Skrahina, A; Solodovnikova, V; Yedilbayev, A | 1 |
Bax, HI; de Steenwinkel, JEM; Keutzer, L; Pieterman, ED; Simonsson, USH; van den Berg, S; van der Meijden, A; Wang, H; Zimmerman, MD | 1 |
Comins, K; Conradie, F; Cramer, YS; De Los Rios, J; Diacon, AH; Donahue, K; Dooley, KE; Hafner, R; Lama, JR; Maartens, G; Moran, L; Morganroth, J; Rosenkranz, SL; Shenje, J; von Groote-Bidlingmaier, F | 1 |
Acharya, S; Chavan, V; Das, M; Dhakulkar, S; Ferlazzo, G; Isaakidis, P; Iyer, A; Kalon, S; Mansoor, H; Meneguim, AC; Oswal, V; Ravi, S; Rebello, L; Shah, D; Sutar, N; Thakur, HP; Vengurlekar, D | 1 |
Bacchetti, P; Dheda, K; Esmail, A; Gandhi, M; Gerona, R; Huo, S; Metcalfe, J; Reckers, A | 1 |
Adenov, MM; Algozhin, YZ; Berikova, EA; Issayeva, AM; Maretbayeva, SM; Rakisheva, AS; Rich, ML; Seung, KJ; Stambekova, AT; Yedilbayev, A; Yeraliyeva, LT | 1 |
Hwang, H; Jeon, D; Kang, H; Kwon, YS; Shim, TS; Yim, JJ | 1 |
Acquah, R; Daniels, J; Furin, J; Loveday, M; Mohr-Holland, E; Mudaly, V; Reuter, A | 1 |
Kashiyama, E; Kim, S; Masuda, M; Sasabe, H; Sasahara, K; Sasaki, T; Shibata, M; Takeuchi, K; Umehara, K | 1 |
Bao, J; Cheng, Q; Fan, J; He, P; He, W; Li, Y; Liu, C; Liu, D; Ma, A; Song, Y; Zhao, B; Zhao, Y | 1 |
Campino, S; Clark, TG; Gomes, P; Gómez-González, PJ; Hibberd, ML; Napier, G; Perdigao, J; Phelan, JE; Portugal, I; Puyen, ZM; Santos-Lazaro, D; Viveiros, M | 1 |
Hafkin, J; Karlsson, MO; Mallikaarjun, S; Sasaki, T; Svensson, EM; Wang, X; Wang, Y | 1 |
Kumari, D; Perveen, S; Sharma, R; Singh, K | 1 |
Adenov, M; Adnan, S; Ahmed, S; Bastard, M; Coutisson, S; Danielyan, N; Franke, MF; Hewison, C; Huerga, H; Islam, S; Janmohamed, A; Kamene Kimenye, M; Karakozian, H; Khan, P; Khan, U; Kholikulov, B; Kirakosyan, O; Krisnanda, A; Kumsa, A; Lachenal, N; Leblanc, G; Lecca, L; Mamsa, S; Melikyan, N; Mitnick, CD; Nkuebe, M; Osso, E; Padayachee, S; Rich, ML; Seung, KJ; Thit, P; Varaine, F | 1 |
Bax, HI; De Steenwinkel, JEM; Lenaerts, A; Mudde, SE; Upton, AM | 1 |
Antony, S; Bodhanwala, M; Jaiswal, A; Parmar, M; Sachdeva, KS; Salve, J; Shah, D; Shah, I; Tipre, P | 1 |
Ahmed, S; Bastard, M; Franke, MF; Grium Tefera, D; Hewison, C; Holtzman, D; Huerga, H; Islam, S; Jacques Leblanc, G; Khan, PY; Khan, U; Kumsa, A; Lachenal, N; Leonovich, O; Mamsa, S; Manzur-Ul-Alam, M; Melikyan, N; Mitnick, CD; Myint, Z; Osso, E; Padayachee, S; Rafi Siddiqui, M; Rashitov, M; Rich, ML; Salahuddin, N; Salia, G; Sánchez, E; Serobyan, A; Seung, KJ; Varaine, F; Vetushko, D; Yeghiazaryan, L | 1 |
Carr, W; Converse, PJ; Dartois, V; Dooley, KE; Garcia, A; Kurbatova, E; Nuermberger, EL; Stout, JE; Tasneen, R; Vernon, AA; Zimmerman, MD | 1 |
De Leon, A; Frias, M; Garcia-Prats, AJ; Gler, MT; Hafkin, J; Hesseling, AC; Malikaarjun, S; Schaaf, HS; van der Laan, L | 1 |
Duong, TV; Nguyen, HT; Taylor, LS | 1 |
De Los Rios, J; Diacon, AH; Dooley, KE; Karlsson, MO; Maartens, G; Shenje, J; Svensson, EM; Tanneau, L; Upton, CM; Wiesner, L | 1 |
Cramer, YS; Diacon, AH; Dooley, KE; Karlsson, MO; Maartens, G; Morganroth, J; Rosenkranz, SL; Shenje, J; Svensson, EM; Tanneau, L; Upton, CM | 1 |
Apolisi, I; Beko, B; Cengani, L; Cox, H; Daniels, J; Fatshe, S; Furin, J; Gumede, N; Joseph, K; Mathee, S; Maugans, C; Memani, B; Reuter, A; Tyeku, N | 1 |
Andersen, ÅB; Dahl, VN; Guglielmetti, L; Holmgaard, FB; Lillebaek, T; Wejse, C | 1 |
Millard, J; Nimmo, C; O'Donnell, M; Rimmer, S | 1 |
Alghamdi, WA; Alshaer, MH; Avaliani, Z; Barbakadze, K; Benkeser, D; Blumberg, HM; Jin, Y; Kempker, RR; Kipiani, M; Maranchick, NF; Mikiashvili, L; Peloquin, CA | 1 |
43 review(s) available for oxazoles and opc-67683
Article | Year |
---|---|
Advances in the treatment of tuberculosis.
Topics: Adamantane; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Drugs, Investigational; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin; Treatment Refusal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2007 |
OPC-67683.
Topics: Animals; Antitubercular Agents; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis | 2008 |
New anti-tuberculosis drugs with novel mechanisms of action.
Topics: Adamantane; Animals; Antitubercular Agents; Diarylquinolines; Drug Design; Drug Resistance, Multiple, Bacterial; Ethylenediamines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Quinolines; Structure-Activity Relationship; Tuberculosis, Pulmonary | 2008 |
[Tuberculosis: new treatment options and updated recommendations].
Topics: Antitubercular Agents; Aza Compounds; Cross-Sectional Studies; Diagnosis, Differential; Diarylquinolines; Fluoroquinolones; Germany; Humans; Moxifloxacin; Nitroimidazoles; Oxazoles; Prognosis; Quinolines; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2013 |
An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds.
Topics: Anti-HIV Agents; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Design; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant | 2013 |
Tuberculosis: clinical trials and new drug regimens.
Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2014 |
Delamanid: first global approval.
Topics: Antitubercular Agents; Drug Approval; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2014 |
Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability.
Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2015 |
Delamanid: a review of its use in patients with multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2015 |
Novel drugs against tuberculosis: a clinician's perspective.
Topics: Adamantane; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarylquinolines; Drug Therapy, Combination; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Nitroimidazoles; Oxazoles; Oxazolidinones; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2015 |
Tuberculosis treatment and drug regimens.
Topics: Antitubercular Agents; China; Diarylquinolines; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; USSR | 2015 |
Delamanid (OPC-67683) for treatment of multi-drug-resistant tuberculosis.
Topics: Adult; Antitubercular Agents; Europe; Extensively Drug-Resistant Tuberculosis; Humans; Japan; Mycobacterium tuberculosis; Mycolic Acids; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; World Health Organization | 2015 |
Profile of delamanid for the treatment of multidrug-resistant tuberculosis.
Topics: Animals; Antitubercular Agents; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Long QT Syndrome; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Risk Assessment; Risk Factors; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2015 |
Delamanid for the treatment of pulmonary multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Drug Interactions; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2015 |
Access to new medications for the treatment of drug-resistant tuberculosis: patient, provider and community perspectives.
Topics: Antitubercular Agents; Compassionate Use Trials; Diarylquinolines; Health Services Accessibility; Humans; Linezolid; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Vulnerable Populations | 2015 |
Bedaquiline and delamanid in tuberculosis.
Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Interactions; Drug Resistance, Bacterial; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2015 |
Management of drug resistantTB in patients with HIV co-infection.
Topics: Antitubercular Agents; Coinfection; Diarylquinolines; Disease Management; Extensively Drug-Resistant Tuberculosis; HIV Infections; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; World Health Organization | 2015 |
Challenges facing the drug discovery pipeline for non-tuberculous mycobacteria.
Topics: Adamantane; Aminopyridines; Anti-Bacterial Agents; Azepines; Benzamides; Clinical Trials as Topic; Diarylquinolines; Drug Discovery; Ethylenediamines; Fluoroquinolones; Humans; Minocycline; Mycobacterium Infections, Nontuberculous; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles; Piperazines; Spiro Compounds; Thiazines; Tigecycline; Uridine | 2016 |
Biotransformation and bioactivation reactions - 2015 literature highlights.
Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles | 2016 |
Adverse effects of oral second-line antituberculosis drugs in children.
Topics: Age Factors; Antitubercular Agents; Child; Diarylquinolines; Dose-Response Relationship, Drug; HIV Infections; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Individualizing management of extensively drug-resistant tuberculosis: diagnostics, treatment, and biomarkers.
Topics: Antitubercular Agents; Biomarkers; Clinical Trials as Topic; Coinfection; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; HIV Infections; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Precision Medicine | 2017 |
Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis: A case report and review of the literature.
Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Italy; Male; Nitroimidazoles; Oxazoles | 2016 |
Use of bedaquiline and delamanid in diabetes patients: clinical and pharmacological considerations.
Topics: Aged; Animals; Antitubercular Agents; Arrhythmias, Cardiac; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diarylquinolines; Drug Interactions; Drug Monitoring; Humans; Hypoglycemic Agents; Middle Aged; Nitroimidazoles; Oxazoles; Polypharmacy; Risk Assessment; Risk Factors; Tuberculosis | 2016 |
Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2017 |
(Re)moving the needle: prospects for all-oral treatment for multidrug-resistant tuberculosis.
Topics: Administration, Oral; Antitubercular Agents; Clinical Trials, Phase III as Topic; Diarylquinolines; Evidence-Based Medicine; Humans; Linezolid; Needles; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant | 2016 |
Delamanid in the treatment of multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Clinical Protocols; Clinical Trials, Phase III as Topic; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant | 2016 |
Current therapies for the treatment of multidrug-resistant tuberculosis in children in India.
Topics: Antitubercular Agents; Child; Diarylquinolines; Drug Administration Schedule; Humans; India; Microbial Sensitivity Tests; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2017 |
Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?
Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; World Health Organization | 2018 |
The devil we know: is the use of injectable agents for the treatment of MDR-TB justified?
Topics: Antitubercular Agents; Diarylquinolines; Health Services Accessibility; Human Rights; Humans; Injections; Nitroimidazoles; Oxazoles; Patient-Centered Care; Tuberculosis, Multidrug-Resistant | 2017 |
Neoteric advancement in TB drugs and an overview on the anti-tubercular role of peptides through computational approaches.
Topics: Antitubercular Agents; Computational Biology; Diarylquinolines; Drug Design; Extensively Drug-Resistant Tuberculosis; Humans; Models, Molecular; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Peptides; Tuberculosis; Tuberculosis, Multidrug-Resistant; World Health Organization | 2018 |
Multi and extensively drug-resistant pulmonary tuberculosis: advances in diagnosis and management.
Topics: Adolescent; Antitubercular Agents; Child; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis.
Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Repositioning; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles | 2018 |
Combined treatment of drug-resistant tuberculosis with bedaquiline and delamanid: a systematic review.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2018 |
Genetics and roadblocks of drug resistant tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Epistasis, Genetic; Humans; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Phylogeny; Tuberculosis, Multidrug-Resistant | 2019 |
Bedaquiline and delamanid in the treatment of multidrug-resistant tuberculosis: Promising but challenging.
Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Electrocardiography; Humans; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
New drugs to treat difficult tuberculous and nontuberculous mycobacterial pulmonary disease.
Topics: Amikacin; Anti-Bacterial Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Liposomes; Lung Diseases; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Nitroimidazoles; Oxazoles | 2019 |
The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Linezolid; Nitroimidazoles; Oxazoles; Periodicals as Topic; Pulmonary Medicine; Societies, Medical; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2019 |
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pharmaceutical Preparations; Tuberculosis, Multidrug-Resistant | 2020 |
Delamanid Resistance: Update and Clinical Management.
Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2020 |
Bedaquiline and delamanid for drug-resistant tuberculosis: a clinician's perspective.
Topics: Antitubercular Agents; Child; Clinical Trials as Topic; Diarylquinolines; Drug Therapy, Combination; Female; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pregnancy; Tuberculosis, Multidrug-Resistant | 2020 |
Evolution of newer regimens in TB from RNTCP to NTEP.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary | 2020 |
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin | 2022 |
Efficacy and Tolerability of Concomitant Use of Bedaquiline and Delamanid for Multidrug- and Extensively Drug-Resistant Tuberculosis: A Systematic Review and Meta-Analysis.
Topics: Antitubercular Agents; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2023 |
14 trial(s) available for oxazoles and opc-67683
Article | Year |
---|---|
Early bactericidal activity of delamanid (OPC-67683) in smear-positive pulmonary tuberculosis patients.
Topics: Adolescent; Adult; Antitubercular Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult | 2011 |
Delamanid for multidrug-resistant pulmonary tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Survival Analysis; Tuberculosis, Multidrug-Resistant; Young Adult | 2012 |
Clinical benefit of delamanid (OPC-67683) in the treatment of multidrug-resistant tuberculosis patients in China.
Topics: Adolescent; Adult; Antitubercular Agents; China; Double-Blind Method; Female; Humans; Male; Mental Disorders; Middle Aged; Nitroimidazoles; Oxazoles; Placebo Effect; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2013 |
Long-term mortality assessment of multidrug-resistant tuberculosis patients treated with delamanid.
Topics: Biomarkers; Follow-Up Studies; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2015 |
Delamanid for Extensively Drug-Resistant Tuberculosis.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome | 2015 |
Simultaneous quantitation of delamanid (OPC-67683) and its eight metabolites in human plasma using UHPLC-MS/MS.
Topics: Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Limit of Detection; Nitroimidazoles; Oxazoles; Placebos; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
Building clinical trial capacity to develop a new treatment for multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Capacity Building; Clinical Protocols; Documentation; Drug Approval; Humans; International Cooperation; Nitroimidazoles; Oxazoles; Research Design; Tuberculosis, Multidrug-Resistant | 2016 |
MIC of Delamanid (OPC-67683) against Mycobacterium tuberculosis Clinical Isolates and a Proposed Critical Concentration.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary | 2016 |
Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects.
Topics: Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Ethambutol; Female; Healthy Volunteers; Humans; Isoniazid; Male; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin | 2016 |
Efficacy and safety of delamanid in combination with an optimised background regimen for treatment of multidrug-resistant tuberculosis: a multicentre, randomised, double-blind, placebo-controlled, parallel group phase 3 trial.
Topics: Antitubercular Agents; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Nitroimidazoles; Oxazoles; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2019 |
Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, m
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Humans; Levofloxacin; Linezolid; Male; Middle Aged; Multicenter Studies as Topic; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Republic of Korea; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2019 |
QT effects of bedaquiline, delamanid, or both in patients with rifampicin-resistant tuberculosis: a phase 2, open-label, randomised, controlled trial.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Nitroimidazoles; Oxazoles; Peru; Rifampin; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2021 |
Delamanid Added to an Optimized Background Regimen in Children with Multidrug-Resistant Tuberculosis: Results of a Phase I/II Clinical Trial.
Topics: Adult; Antitubercular Agents; Child; Child, Preschool; Female; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2022 |
Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens.
Topics: Diarylquinolines; Electrocardiography; Heart Rate; Humans; Nitroimidazoles; Oxazoles | 2022 |
146 other study(ies) available for oxazoles and opc-67683
Article | Year |
---|---|
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis | 2006 |
Bactericidal activity of OPC-67683 against drug-tolerant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Time Factors | 2007 |
[Recent progress in mycobacteriology].
Topics: Animals; Antitubercular Agents; Bacterial Proteins; Bacteriology; DNA-Binding Proteins; Drug Design; Humans; Immunoenzyme Techniques; Japan; Mice; Minisatellite Repeats; Molecular Epidemiology; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Serologic Tests; Tuberculosis Vaccines; Tuberculosis, Pulmonary | 2007 |
Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824.
Topics: Antitubercular Agents; Crystallography, X-Ray; Drug Resistance, Bacterial; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Stereoisomerism; Structure-Activity Relationship | 2008 |
[Some new antitubercular agents].
Topics: Acetamides; Antitubercular Agents; Diarylquinolines; Humans; Linezolid; Nitroimidazoles; Oxazoles; Oxazolidinones; Quinolines | 2008 |
A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Microbial Viability; Molecular Structure; Mycobacterium bovis; Mycobacterium tuberculosis; Nitro Compounds; Nitroimidazoles; Oxazoles; Polycyclic Aromatic Hydrocarbons | 2008 |
Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles.
Topics: Antitubercular Agents; Cloning, Molecular; Flavins; Kinetics; Mycobacterium tuberculosis; Nitric Oxide; Nitroimidazoles; Nitroreductases; Oxazoles; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2012 |
Confronting multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Epidemics; Female; Humans; Male; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2012 |
Trial watch: Novel antimicrobial fights TB resistance.
Topics: Antitubercular Agents; Clinical Trials, Phase II as Topic; Drug Design; Humans; Medication Adherence; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2012 |
Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Drug Administration Schedule; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2013 |
Principles for designing future regimens for multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Approval; Drug Design; Drug Resistance, Multiple, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2014 |
Improving the health of the tuberculosis drug pipeline.
Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Approval; Drug Discovery; Global Health; Humans; Nitroimidazoles; Oxazoles; Research Support as Topic; Tuberculosis | 2014 |
ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: case study of compassionate delamanid use.
Topics: Antitubercular Agents; Child; Compassionate Use Trials; Disease Outbreaks; Europe; Extensively Drug-Resistant Tuberculosis; Humans; Italy; Male; Nitroimidazoles; Oxazoles; Program Development; Societies, Medical; Treatment Outcome; World Health Organization | 2014 |
In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Caco-2 Cells; Cell Line, Tumor; Disease Models, Animal; Drug Interactions; Drug Resistance, Bacterial; Female; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Tuberculosis | 2015 |
Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis.
Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Pyrazinamide; Random Allocation; Tuberculosis | 2015 |
Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.
Topics: Antitubercular Agents; Cells, Cultured; Cytochrome P-450 Enzyme System; Drug Interactions; Hepatocytes; Humans; Microsomes, Liver; Nitroimidazoles; Oxazoles; RNA, Messenger | 2014 |
Access sought to tuberculosis drug from nutraceutical company.
Topics: Antitubercular Agents; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles | 2015 |
Drug-resistance mechanisms and tuberculosis drugs.
Topics: Antitubercular Agents; Diarylquinolines; Drug Approval; Humans; Mutation; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2015 |
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
Topics: Administration, Oral; Animals; Antitubercular Agents; Biological Availability; Chemistry Techniques, Synthetic; Chronic Disease; Disease Models, Animal; Humans; Male; Mice, Inbred BALB C; Mice, Inbred Strains; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Tuberculosis | 2015 |
Cost effectiveness of treating multi-drug resistant tuberculosis by adding Deltyba™ to background regimens in Germany.
Topics: Adult; Antitubercular Agents; Cost-Benefit Analysis; Drug Costs; Female; Germany; Humans; Male; Markov Chains; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2015 |
Determination of MIC distribution and epidemiological cutoff values for bedaquiline and delamanid in Mycobacterium tuberculosis using the MGIT 960 system equipped with TB eXiST.
Topics: Antitubercular Agents; Diarylquinolines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Reference Values; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2015 |
Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo.
Topics: Albumins; Animals; Antitubercular Agents; Biotransformation; Cytochrome P-450 Enzyme System; Dogs; Female; Humans; Hydroxylation; Isoenzymes; Ketones; Male; Mice; Mice, Inbred ICR; Nitroimidazoles; Oxazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2015 |
Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma.
Topics: Animals; Antitubercular Agents; Biotransformation; Dogs; Half-Life; Humans; Hydrogen-Ion Concentration; Mice; Molecular Weight; Nitroimidazoles; Oxazoles; Rabbits; Rats; Serum Albumin; Temperature | 2015 |
Classification of antituberculosis drugs: a new proposal based on the most recent evidence.
Topics: Antitubercular Agents; Carbapenems; Clavulanic Acid; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Linezolid; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization | 2015 |
Compassionate and optimum use of new tuberculosis drugs.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Health Services Accessibility; Humans; Male; Nitroimidazoles; Oxazoles; Pneumonectomy | 2015 |
Cost-effectiveness of incorporating bedaquiline into a treatment regimen for MDR/XDR-TB in Germany.
Topics: Antitubercular Agents; Computer Simulation; Cost-Benefit Analysis; Diarylquinolines; Drug Costs; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Germany; Humans; Markov Chains; Models, Economic; Nitroimidazoles; Oxazoles; Pyrazinamide; Tuberculosis, Multidrug-Resistant | 2015 |
Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Male; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2015 |
Barriers to new drug development in respiratory disease.
Topics: Antitubercular Agents; Awards and Prizes; Diarylquinolines; Drug Discovery; Extensively Drug-Resistant Tuberculosis; Humans; Motivation; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Identification of patients who could benefit from bedaquiline or delamanid: a multisite MDR-TB cohort study.
Topics: Adult; Antitubercular Agents; Bacterial Load; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Eswatini; Female; Humans; Kenya; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Nitroimidazoles; Odds Ratio; Oxazoles; Patient Selection; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; USSR; Young Adult | 2016 |
Reciprocity and Ethical Tuberculosis Treatment and Control.
Topics: Antitubercular Agents; Beneficence; Communicable Disease Control; Congresses as Topic; Diarylquinolines; Directly Observed Therapy; Ethical Analysis; Ethical Theory; Global Health; Humans; Moral Obligations; Nitroimidazoles; Oxazoles; Patient Isolation; Personal Autonomy; Pharmacovigilance; Poverty; Public Health; Social Justice; Social Responsibility; Tuberculosis, Laryngeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Virtues | 2016 |
Delamanid and Bedaquiline Resistance in Mycobacterium tuberculosis Ancestral Beijing Genotype Causing Extensively Drug-Resistant Tuberculosis in a Tibetan Refugee.
Topics: Adult; Antitubercular Agents; Beijing; Compassionate Use Trials; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Refugees; Tibet | 2016 |
[New antitubercular agents are not where where we need them to be].
Topics: Antitubercular Agents; Developing Countries; Diarylquinolines; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2015 |
Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Drug Approval; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Global Introduction of New Multidrug-Resistant Tuberculosis Drugs-Balancing Regulation with Urgent Patient Needs.
Topics: Antitubercular Agents; Diarylquinolines; Drug Prescriptions; Drug Resistance, Bacterial; Drug Utilization; Humans; Legislation, Drug; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters.
Topics: Animals; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Cell Line; Drug Interactions; HEK293 Cells; Humans; Kidney Tubules, Proximal; Neoplasm Proteins; Nitroimidazoles; Octamer Transcription Factor-1; Organic Anion Transporters; Oxazoles; Solute Carrier Proteins; Swine; Tuberculosis, Multidrug-Resistant | 2016 |
Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system.
Topics: Antitubercular Agents; Automation, Laboratory; Colorimetry; Genes, Bacterial; Indicators and Reagents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Polymorphism, Genetic; Sequence Analysis, DNA; Xanthenes | 2016 |
The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Antitubercular Agents; Biotransformation; Disease Models, Animal; Drug Administration Schedule; Drug Dosage Calculations; Drug Repositioning; Female; Hormesis; Leishmania donovani; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oxazoles; Parasitic Sensitivity Tests; Treatment Outcome | 2016 |
Access to new drugs and the global drug-resistant TB crisis: a case series from KwaZulu-Natal, South Africa.
Topics: Adult; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Health Services Accessibility; Humans; Male; Nitroimidazoles; Oxazoles; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2016 |
First case of extensively drug-resistant tuberculosis treated with both delamanid and bedaquiline.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Nitroimidazoles; Oxazoles | 2016 |
Comparison of Effectiveness Between Delamanid and Bedaquiline Among Patients with Multidrug-Resistant Tuberculosis: A Markov Model Simulation Study.
Topics: Aged; Diarylquinolines; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Tuberculosis, Multidrug-Resistant | 2016 |
A Bayesian response-adaptive trial in tuberculosis: The endTB trial.
Topics: Adaptive Clinical Trials as Topic; Algorithms; Antitubercular Agents; Bayes Theorem; Computer Simulation; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2017 |
Using bedaquiline and delamanid in combination and safely.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Global Health; Humans; Nitroimidazoles; Oxazoles; Tuberculosis | 2016 |
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine.
Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine.
Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2016 |
Applicability of the shorter 'Bangladesh regimen' in high multidrug-resistant tuberculosis settings.
Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Tuberculosis, Multidrug-Resistant; World Health Organization | 2017 |
Is delamanid a potential agent in the treatment of diseases caused by Mycobacterium avium-intracellulare?
Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Nitroimidazoles; Oxazoles | 2016 |
Delamanid is not metabolized by Salmonella or human nitroreductases: A possible mechanism for the lack of mutagenicity.
Topics: Antitubercular Agents; Bacterial Proteins; Biotransformation; DNA, Bacterial; Humans; Kinetics; Mutagenesis; Mutagenicity Tests; Nitroimidazoles; Nitroreductases; Oxazoles; Oxidation-Reduction; Risk Assessment; Salmonella typhimurium; Substrate Specificity | 2017 |
Estimated generic prices for novel treatments for drug-resistant tuberculosis.
Topics: Algorithms; Antitubercular Agents; Commerce; Diarylquinolines; Drug Costs; Drugs, Generic; Fluoroquinolones; Humans; Moxifloxacin; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2017 |
India plans to expand access to new tuberculosis drug.
Topics: Antitubercular Agents; Diarylquinolines; Health Services Accessibility; Humans; India; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2017 |
Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany.
Topics: Adult; Antitubercular Agents; Clinical Protocols; Clinical Trials as Topic; Cost-Benefit Analysis; Diarylquinolines; Drug Costs; Drug Therapy, Combination; Female; Germany; Humans; Linezolid; Male; Nitroimidazoles; Observational Studies as Topic; Oxazoles; Quality-Adjusted Life Years; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases.
Topics: Animals; Antitubercular Agents; Chagas Disease; Disease Models, Animal; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Structure-Activity Relationship; Thiazoles; Tuberculosis | 2017 |
Biopharmaceutic parameters, pharmacokinetics, transport and CYP-mediated drug interactions of IIIM-017: A novel nitroimidazooxazole analogue with anti-tuberculosis activity.
Topics: Animals; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Computer Simulation; Drug Interactions; Humans; Mice, Inbred BALB C; Microsomes, Liver; Nitroimidazoles; Oxazoles | 2017 |
Topics: Antitubercular Agents; Beijing; China; Clofazimine; Diarylquinolines; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Gatifloxacin; Humans; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles | 2017 |
Early outcomes in MDR-TB and XDR-TB patients treated with delamanid under compassionate use.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Communicable Disease Control; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Female; Global Health; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization | 2017 |
Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary; Young Adult | 2017 |
Six-Month Response to Delamanid Treatment in MDR TB Patients.
Topics: Adolescent; Antitubercular Agents; Female; Hepatitis C; HIV Infections; Humans; Male; Nitroimidazoles; Oxazoles; Retrospective Studies; Tuberculosis, Multidrug-Resistant | 2017 |
Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Azithromycin; Child; Clarithromycin; Clofazimine; Diarylquinolines; Female; Fluoroquinolones; Follow-Up Studies; Humans; Lost to Follow-Up; Macrolides; Male; Middle Aged; Moxifloxacin; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles; Retrospective Studies; Tuberculosis, Multidrug-Resistant; Young Adult | 2017 |
Bedaquiline or delamanid for rifampin-resistant tuberculosis?
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rifampin; Tuberculosis, Multidrug-Resistant | 2017 |
Incorporating social justice and stigma in cost-effectiveness analysis: drug-resistant tuberculosis treatment.
Topics: Antitubercular Agents; Cost-Benefit Analysis; Decision Trees; Diarylquinolines; Humans; Models, Theoretical; Nitroimidazoles; Oxazoles; Social Justice; Social Stigma; South Africa; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
Interim outcomes of delamanid for the treatment of MDR- and XDR-TB in South Korea.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bacteriological Techniques; Drug-Related Side Effects and Adverse Reactions; Female; Hospitals; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2018 |
Final treatment outcomes of multidrug- and extensively drug-resistant tuberculosis patients in Latvia receiving delamanid-containing regimens.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Extensively Drug-Resistant Tuberculosis; Female; Humans; Latvia; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2017 |
World Health Organization recommendations for multidrug-resistant tuberculosis: should different standards be applied?
Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Humans; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization | 2017 |
Safety and efficacy of exposure to bedaquiline-delamanid in multidrug-resistant tuberculosis: a case series from France and Latvia.
Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; France; Humans; Latvia; Male; Nitroimidazoles; Oxazoles; Patient Safety; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2018 |
Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis.
Topics: Adult; Antitubercular Agents; Colistin; Diarylquinolines; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Male; Medication Adherence; Mycobacterium tuberculosis; Netherlands; Nitroimidazoles; Oxazoles; Patient Isolation; Phenotype; Trimethoprim, Sulfamethoxazole Drug Combination; United Kingdom | 2018 |
Combining bedaquiline and delamanid to treat multidrug-resistant tuberculosis.
Topics: Armenia; Diarylquinolines; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; South Africa; Tuberculosis, Multidrug-Resistant | 2018 |
Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South Africa: a retrospective cohort study.
Topics: Adult; Antitubercular Agents; Armenia; Arrhythmias, Cardiac; Cohort Studies; Diarylquinolines; Drug Therapy, Combination; HIV Infections; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; South Africa; Tuberculosis, Multidrug-Resistant | 2018 |
Mechanisms of resistance to delamanid, a drug for Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Genotype; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Oxazoles; Phenotype; Riboflavin | 2018 |
Bedaquiline and delamanid for the treatment of multidrug-resistant tuberculosis: a multicentre cohort study in Korea.
Topics: Adult; Antitubercular Agents; Cohort Studies; Diarylquinolines; Drug Administration Schedule; Female; Geography; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant; World Health Organization | 2018 |
Using new TB tools: global rhetoric and ground reality.
Topics: Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2018 |
Global programmatic use of bedaquiline and delamanid for the treatment of multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Humans; Internationality; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2018 |
The World Health Organization global aDSM database: generating evidence on the safety of new treatment regimens for drug-resistant tuberculosis.
Topics: Antitubercular Agents; Communicable Disease Control; Databases, Factual; Diarylquinolines; Humans; Infectious Disease Medicine; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Patient Safety; Public Health; Rifampin; Tuberculosis, Multidrug-Resistant; World Health Organization | 2018 |
Will regulatory issues continue to be a major barrier to access to bedaquiline and delamanid?
Topics: Antitubercular Agents; Diarylquinolines; Diffusion of Innovation; Drug and Narcotic Control; Drug Approval; Global Health; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2018 |
Early experience with delamanid-containing regimens in the treatment of complicated multidrug-resistant tuberculosis in Hong Kong.
Topics: Adult; Antitubercular Agents; Female; Hong Kong; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2018 |
Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa.
Topics: Adult; Antitubercular Agents; Female; Humans; Logistic Models; Male; Nitroimidazoles; Oxazoles; Retrospective Studies; Rifampin; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.
Topics: Antitubercular Agents; Cardiotoxicity; Cross-Sectional Studies; Diarylquinolines; Electrocardiography; Europe; Humans; Internationality; Long QT Syndrome; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2018 |
Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Reproducibility of Results; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2018 |
Modelling the long-acting administration of anti-tuberculosis agents using PBPK: a proof of concept study.
Topics: Adolescent; Adult; Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Liberation; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Latent Tuberculosis; Male; Middle Aged; Nitroimidazoles; Oxazoles; Proof of Concept Study; Rifampin; Treatment Outcome; Young Adult | 2018 |
Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea.
Topics: Antitubercular Agents; Diarylquinolines; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant | 2018 |
Notes from the Field: Acquisition of Delamanid Under a Compassionate Use Program for Extensively Drug-Resistant Tuberculosis - United States, 2017.
Topics: Antitubercular Agents; Centers for Disease Control and Prevention, U.S.; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; United States | 2018 |
Coenzyme F
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Glucosephosphate Dehydrogenase; Ligases; Methanobacteriaceae; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Polyglutamic Acid; Recombinant Proteins; Riboflavin; Tetrahydrofolates | 2018 |
Cost-effectiveness of bedaquiline or delamanid plus background regimen for multidrug-resistant tuberculosis in a high-income intermediate burden city of China.
Topics: Adult; Cost-Benefit Analysis; Diarylquinolines; Follow-Up Studies; Hong Kong; Humans; Middle Aged; Monte Carlo Method; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Retrospective Studies; Socioeconomic Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
Compassionate use of delamanid in combination with bedaquiline for the treatment of multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Compassionate Use Trials; Diarylquinolines; Drug Therapy, Combination; Female; HIV Infections; Humans; Internationality; Male; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Young Adult | 2019 |
Delamanid: does it have a role in tuberculosis treatment?
Topics: Double-Blind Method; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2019 |
[EXPERIENCE OF USE OF NEW ANTI-TUBERCULOUS DRUG, DELAMANID IN MULTI- AND EXTENSIVELY DRUG RESISTANT TUBERCULOSIS CASES IN OUR HOSPITAL].
Topics: Adult; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniazid; Male; Middle Aged; Nitroimidazoles; Oxazoles | 2016 |
Delamanid (Deltyba°) and multidrug-resistant pulmonary tuberculosis.
Topics: Antitubercular Agents; Electrocardiography; Humans; Long QT Syndrome; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2017 |
'Those who cannot remember the past are condemned to repeat it': Drug-susceptibility testing for bedaquiline and delamanid.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles | 2019 |
Journey of tuberculosis control in India.
Topics: Antitubercular Agents; Diarylquinolines; Directly Observed Therapy; Goals; History, 20th Century; History, 21st Century; Humans; India; National Health Programs; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2019 |
Early efficacy and safety of Bedaquiline and Delamanid given together in a "Salvage Regimen" for treatment of drug-resistant tuberculosis.
Topics: Adult; Cardiotoxicity; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Imipenem; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Salvage Therapy; Sputum; Survival Rate; Tuberculosis, Multidrug-Resistant; Young Adult | 2019 |
The STREAM trial: missed opportunities and lessons for future clinical trials.
Topics: Antitubercular Agents; Deafness; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Time Factors; Tuberculosis, Multidrug-Resistant | 2019 |
Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome | 2019 |
Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Male; Nitroimidazoles; Oxazoles; Pilot Projects; Tuberculosis; Tuberculosis, Multidrug-Resistant; World Health Organization | 2019 |
Bedaquiline and delamanid in combination for treatment of drug-resistant tuberculosis.
Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Drug Therapy, Combination; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
Acquired Drug Resistance: Recognizing the Potential of Repurposed Drugs.
Topics: Diarylquinolines; Drug Resistance; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles | 2019 |
Topics: Anti-Bacterial Agents; Antitubercular Agents; Diarylquinolines; Humans; Macrolides; Microbial Sensitivity Tests; Mycobacterium abscessus; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles | 2019 |
In vitro interaction profiles of the new antitubercular drugs bedaquiline and delamanid with moxifloxacin against clinical Mycobacterium tuberculosis isolates.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Tuberculosis, Multidrug-Resistant; Xanthenes | 2019 |
Final treatment outcomes of delamanid-containing regimens in patients with MDR-/XDR-TB in South Korea.
Topics: Adult; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2019 |
Undergraduate Medical Teaching: Time to integrate?
Topics: Antitubercular Agents; Drug Approval; Education, Medical; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2018 |
Current Status of Delamanid in the Management of MDR Tuberculosis.
Topics: Antitubercular Agents; Child; Female; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pregnancy; Tuberculosis, Multidrug-Resistant | 2018 |
Discovery and evaluation of novel nitrodihydroimidazooxazoles as promising anti-tuberculosis agents.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Permeability; Solubility; Structure-Activity Relationship; Vero Cells | 2019 |
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
Topics: Aerobiosis; Antitubercular Agents; Cell Wall; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; RNA, Bacterial; Sequence Analysis, RNA | 2019 |
Delamanid Central Nervous System Pharmacokinetics in Tuberculous Meningitis in Rabbits and Humans.
Topics: Animals; Antitubercular Agents; Central Nervous System; Female; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rabbits; Treatment Outcome; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant | 2019 |
The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Nitroimidazoles; Observational Studies as Topic; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
A regimen containing bedaquiline and delamanid compared to bedaquiline in patients with drug-resistant tuberculosis.
Topics: Antitubercular Agents; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2020 |
Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.
Topics: Antitubercular Agents; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2020 |
Clinical Outcomes Among Patients With Drug-resistant Tuberculosis Receiving Bedaquiline- or Delamanid-Containing Regimens.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Georgia; Humans; Male; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2020 |
Treatment of multidrug-resistant pulmonary tuberculosis with delamanid based on Japanese guideline recommendations.
Topics: Adult; Antitubercular Agents; Drug Resistance, Multiple; Female; Humans; Japan; Male; Middle Aged; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Pulmonary | 2020 |
Bedaquiline and Delamanid in Children With XDR Tuberculosis: What is prolonged QTc?
Topics: Adolescent; Antitubercular Agents; Child; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Sputum; Tomography, X-Ray Computed | 2020 |
Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Oxazoles; Polymorphism, Genetic; Protein Engineering | 2020 |
Interim treatment outcomes in multidrug-resistant tuberculosis using bedaquiline and/or delamanid in South Korea.
Topics: Age Factors; Aged; Body Mass Index; Diarylquinolines; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Risk Factors; Safety; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2020 |
Interim treatment outcomes in multidrug-resistant tuberculosis patients treated sequentially with bedaquiline and delamanid.
Topics: Adult; Aged; Antitubercular Agents; Diarylquinolines; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
An Experience with Delamanid in an XDR TB Case - Case Report.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles | 2021 |
Correspondence regarding "Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa".
Topics: Humans; Nitroimidazoles; Oxazoles; Retrospective Studies; Rifampin; South Africa; Tuberculosis, Multidrug-Resistant | 2020 |
Multidrug Resistant Tuberculosis With Simultaneously Acquired Drug Resistance to Bedaquiline and Delamanid.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2021 |
Operational Research on the Treatment of Drug-Resistant Tuberculosis: Exciting Results That Need to Be Protected.
Topics: Diarylquinolines; Humans; Nitroimidazoles; Operations Research; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2021 |
Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients.
Topics: Africa; Antitubercular Agents; Asia; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pharmaceutical Preparations; South America; Tuberculosis, Multidrug-Resistant | 2020 |
Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains.
Topics: Antitubercular Agents; Diarylquinolines; Genomics; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2020 |
Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration.
Topics: Administration, Oral; Animals; Cinnarizine; Humans; Liquid Crystals; Nitroimidazoles; Oxazoles; Rats; Solubility | 2021 |
Mutations in
Topics: Animals; Antitubercular Agents; Mice; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles | 2020 |
One Step Forward: Successful End-of-Treatment Outcomes of Patients With Drug-Resistant Tuberculosis Who Received Concomitant Bedaquiline and Delamanid in Mumbai, India.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult | 2021 |
Concurrent use of bedaquiline and delamanid for the treatment of fluoroquinolone-resistant multidrug-resistant tuberculosis: a nationwide cohort study in South Korea.
Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Fluoroquinolones; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant | 2021 |
Population Pharmacokinetic Analysis of Delamanid in Patients with Pulmonary Multidrug-Resistant Tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Humans; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult | 2020 |
Compassionate use of delamanid in adults and children for drug-resistant tuberculosis: 5-year update.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Compassionate Use Trials; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2021 |
Pharmacokinetics of bedaquiline, delamanid and clofazimine in patients with multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2021 |
Effectiveness and safety of delamanid- or bedaquiline-containing regimens among children and adolescents with multidrug resistant or extensively drug resistant tuberculosis: A nationwide study from Belarus, 2015-19.
Topics: Adolescent; Antitubercular Agents; Child; Cohort Studies; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Republic of Belarus | 2021 |
Effectiveness and cardiovascular safety of delamanid-containing regimens in adults with multidrug-resistant or extensively drug-resistant tuberculosis: A nationwide cohort study from Belarus, 2016-18.
Topics: Adult; Antitubercular Agents; Cohort Studies; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Republic of Belarus; Treatment Outcome | 2021 |
Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model.
Topics: Animals; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Linezolid; Mice; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Recurrence; Tuberculosis | 2021 |
Treatment outcomes of children and adolescents receiving drug-resistant TB treatment in a routine TB programme, Mumbai, India.
Topics: Adolescent; Ambulatory Care Facilities; Antitubercular Agents; Child; Child, Preschool; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; India; Infant; Infant, Newborn; Male; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2021 |
Development and validation of a liquid chromatography-tandem mass spectrometry method for quantifying delamanid and its metabolite in small hair samples.
Topics: Chromatography, Liquid; Hair; Humans; Limit of Detection; Linear Models; Nitroimidazoles; Oxazoles; Reproducibility of Results; Tandem Mass Spectrometry; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2021 |
Culture conversion at six months in patients receiving bedaquiline- and delamanid-containing regimens for the treatment of multidrug-resistant tuberculosis.
Topics: Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2021 |
Outcomes of Multidrug-Resistant Tuberculosis Treated With Bedaquiline or Delamanid.
Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2021 |
Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients.
Topics: Adult; Antitubercular Agents; Child Health; Child, Preschool; Diarylquinolines; Female; Humans; Infant; Infant Health; Linezolid; Nitroimidazoles; Oxazoles; Pregnancy; Pregnancy Outcome; Pregnant Women; South Africa; Tuberculosis, Multidrug-Resistant; Young Adult | 2021 |
Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis.
Topics: Animals; Antitubercular Agents; Dogs; Humans; Mice; Models, Biological; Nitroimidazoles; Oxazoles; Rats; Tuberculosis | 2021 |
Prevalence of Mycobacterium tuberculosis resistant to bedaquiline and delamanid in China.
Topics: China; Diarylquinolines; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Phylogeny; Prevalence; Retrospective Studies | 2021 |
Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid.
Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Humans; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Whole Genome Sequencing | 2021 |
Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Humans; Infant; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2022 |
Safety of Treatment Regimens Containing Bedaquiline and Delamanid in the endTB Cohort.
Topics: Antitubercular Agents; Diarylquinolines; Electrolytes; Humans; Linezolid; Nitroimidazoles; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2022 |
Delamanid or pretomanid? A Solomonic judgement!
Topics: Antitubercular Agents; Diarylquinolines; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2022 |
Feasibility of a "Salvage Regimen" Using Home-based Intravenous Meropenem Therapy With a Delamanid/Bedaquilline Containing Regimen in the Management of MDR/XDR Pediatric Tuberculosis.
Topics: Adolescent; Antitubercular Agents; Child; Extensively Drug-Resistant Tuberculosis; Feasibility Studies; Female; Humans; Male; Meropenem; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2022 |
Safety and Effectiveness Outcomes From a 14-Country Cohort of Patients With Multi-Drug Resistant Tuberculosis Treated Concomitantly With Bedaquiline, Delamanid, and Other Second-Line Drugs.
Topics: Antitubercular Agents; Clofazimine; Cohort Studies; Diarylquinolines; Electrolytes; Fluoroquinolones; Humans; Linezolid; Nitroimidazoles; Oxazoles; Prospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant | 2022 |
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Mice; Mice, Inbred BALB C; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifabutin; Tuberculosis | 2022 |
Combining enabling formulation strategies to generate supersaturated solutions of delamanid: In situ salt formation during amorphous solid dispersion fabrication for more robust release profiles.
Topics: Drug Liberation; Drug Stability; Nitroimidazoles; Oxazoles; Salts; Solubility; Water | 2022 |
Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline.
Topics: Adult; Albumins; Antitubercular Agents; Diarylquinolines; HIV Infections; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2022 |
[Expert consensus on clinical application of delamanid].
Topics: Consensus; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2022 |
Pediatric delamanid treatment for children with rifampicin-resistant TB.
Topics: Antitubercular Agents; Child; Humans; Nitroimidazoles; Oxazoles; Rifampin; Tuberculosis, Multidrug-Resistant | 2022 |
Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB.
Topics: Antitubercular Agents; Diarylquinolines; Female; Humans; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant | 2023 |
The effect of anti-tuberculosis drug pharmacokinetics on QTc prolongation.
Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Humans; Long QT Syndrome; Male; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant | 2023 |