Page last updated: 2024-08-21

oxazoles and opc-67683

oxazoles has been researched along with opc-67683 in 203 studies

Research

Studies (203)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (4.43)29.6817
2010's141 (69.46)24.3611
2020's53 (26.11)2.80

Authors

AuthorsStudies
Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H1
Crismale, C; Saliu, OY; Schwander, SK; Wallis, RS1
Zhang, Y1
Kobayashi, K; Okada, M1
Barry, CE; Dowd, CS; Goodwin, MB; Keller, TH; Knox, JE; Li, X; Lipinski, CA; Manjunatha, UH1
Nau, JY2
Mancera, RL; Rivers, EC1
Budha, NR; Carson, EI; Cho, SH; Franzblau, SG; Hurdle, JG; Lee, RB; Lee, RE; Lenaerts, AJ; McNeil, MR; Meibohm, B; Qi, J; Scherman, MS1
Dawson, R; Diacon, AH; Donald, PR; Geiter, LJ; Hanekom, M; Hittel, N; Narunsky, K; Paccaly, AJ; Venter, A; Wells, CD1
Barry, CE; Boshoff, HI; Cherian, J; Dick, T; Dowd, CS; Gurumurthy, M; Lee, YS; Manjunatha, UH; Mukherjee, T; Nayyar, A; Niyomrattanakit, P; Singh, R; Tay, JA1
Awad, M; Cabrera-Rivero, JL; Chang, J; Danilovits, M; Gao, M; Geiter, LJ; Gler, MT; Koh, WJ; Kurve, A; Ogata, H; Park, SK; Sanchez-Garavito, E; Seaworth, B; Shim, TS; Skripconoka, V; Suh, GY; Suzuki, K; Tupasi, T; Vargas-Vasquez, DE; Wells, CD; Xiao, H1
Chaisson, RE; Nuermberger, EL1
Crunkhorn, S1
Cirule, A; Danilovits, M; Geiter, LJ; Kummik, T; Kurve, A; Leimane, V; Levina, K; Manissero, D; Pehme, L; Skenders, G; Skripconoka, V; Tomson, T; Wells, CD1
Schaberg, T1
Liu, Y; Sha, W; Tang, S; Xiao, H; Zhang, Q1
Boechat, N; Branco, FS; Pinto, AC1
Balasegaram, M; Brigden, G; du Cros, P; Horsburgh, CR; Hughes, J; McIlleron, H; Mitnick, CD; Nuermberger, E; Nyang'wa, BT; Phillips, PP; Rich, M; Varaine, F1
Burki, T1
Jeong, BH; Koh, WJ; Kwon, YS2
Blasi, F; Caminero Luna, J; Centis, R; D'Ambrosio, L; Dara, M; Esposito, S; Marais, B; Matteelli, A; Migliori, GB; Schaaf, HS; Tadolini, M1
Lo, JH; Ryan, NJ1
Cho, S; Franzblau, SG; Kim, Y; Lu, Y; Ma, Z; Mdluli, K; Upton, AM; Wang, B; Wang, Y; Xu, J; Yang, TJ1
Amoabeng, O; Mdluli, KE; Minkowski, A; Nuermberger, EL; Tasneen, R; Upton, AM; Williams, K1
Mizuno, K; Sasahara, K; Shimokawa, Y; Umehara, K; Yoda, N1
Blair, HA; Scott, LJ1
Chang, KC; Heyckendorf, J; Lange, C; Olaru, ID; von Groote-Bidlingmaier, F; Yew, WW1
Centis, R; D'ambrosio, L; Migliori, GB; Sotgiu, G1
Gruber, K1
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G1
Lynch, JB; Szumowski, JD1
Geiter, LJ; Gupta, R; Hittel, N; Wells, CD1
Abubakar, I; Brown, NM; Burman, WJ; Ellington, MJ; Feuerriegel, S; Ismail, NA; Javid, B; Köser, CU; Liddell, K; Moore, D; Niemann, S; Peacock, SJ; Török, ME1
Chopra, S; Dasgupta, A; Soni, I; Thakare, R1
Blaser, A; Denny, WA; Franzblau, SG; Kmentova, I; Ma, Z; Palmer, BD; Sutherland, HS; Thompson, AM; Wan, B; Wang, Y1
Cox, H; Daniels, C; Furin, J; Lessem, E; McKenna, L; Mitnick, CD; Mosidi, T; Reed, C; Seaworth, B; Stillo, J; Tisile, P; von Delft, D1
Diel, R; Hittel, N; Schaberg, T1
Bloemberg, GV; Böttger, EC; Hömke, R; Keller, PM; Ritter, C; Valsesia, G1
Hirao, Y; Kitano, K; Koyama, N; Sasahara, K; Shibata, M; Shimokawa, Y; Umehara, K1
Kitano, K; Koyama, N; Sasahara, K; Shibata, M; Shimokawa, Y; Umehara, K; Yoda, N1
Cirule, A; Gao, M; Geiter, LJ; Gupta, R; Wells, CD; Xiao, H1
Bianchini, S; Blasi, F; Esposito, S1
Brisson, J; Carter, S; Johnston, B; Meng, M; Roth, SE; Smith, B1
Caminero, JA; Scardigli, A1
Cox, H; Furin, J; Lessem, E; Mason, L; Reed, C; Seaworth, B1
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G; Spanevello, A1
Diel, R; Gibbert, J; Wirth, D; Wolfson, LJ1
Chopra, S; Dasgupta, A; De Groote, MA; Soni, I1
Bloemberg, GV; Borrell, S; Böttger, EC; Coscolla, M; Feldmann, J; Gagneux, S; Hömke, R; Keller, PM; Latshang, T; Ritter, C; Rothe, T; Schulthess, B; Stucki, D; Stuckia, D; Trauner, A1
Brigden, G; du Cros, P; Wong, S1
Bastard, M; Bonnet, M; du Cros, P; Hayrapetyan, A; Hewison, C; Khamraev, A; Khurkhumal, S; Kimenye, K; Sanchez-Padilla, E; Telnov, A; Themba, D; Varaine, F1
Dawson, A; Silva, DS; Upshur, RE1
Beckert, P; Hoffmann, H; Hofmann-Thiel, S; Jaton, K; Keller, PM; Kohl, TA; Merker, M; Nedialkova, L; Niemann, S; Rothe, T; Sahalchyk, E1
Brigden, G; Furin, J; Lessem, E; Lynch, S; Rich, M; Vaughan, L1
Ben Amor, Y; Sullivan, T1
Awad, M; Cabrera-Rivero, JL; Cirule, A; Danilovits, M; Gao, M; Geiter, LJ; Gentry, LM; Gupta, R; Sanchez-Garavito, E; Tupasi, T; Vargas-Vasquez, DE; Wells, CD; Xiao, H1
Fujiwara, M; Geiter, L; Kawasaki, M; Kreiswirth, BN; Kurepina, N; Liu, Y; Matsumoto, M; Shashkina, E; Stinson, K; Timm, J; Venter, A1
Hamasako, Y; Hashizume, K; Kashiyama, E; Ohzone, Y; Sasabe, H; Shibata, M; Shimokawa, Y; Umehara, K1
Battaglia, S; Borroni, E; Cabibbe, AM; Cirillo, DM; Hoffmann, H; Hofmann-Thiel, S; Merker, M; Nedialkova, L; Niemann, S; Schena, E; Trovato, A; Utpatel, C1
Auer, JL; Fairlamb, AH; Norval, S; Osuna-Cabello, M; Patterson, S; Read, KD; Simeons, FR; Stojanovski, L; Wyllie, S1
Furin, J; Master, I1
Centis, R; D'Ambrosio, L; Enwerem, M; Lingtsang, RD; Migliori, GB; Sadutshang, TD; Tadolini, M; Tiberi, S2
Baillie, TA; Cyrus Khojasteh, S; Dalvie, D; Rietjens, IM1
Geiter, L; Mallikaarjun, S; Paccaly, A; Patil, S; Petersen, C; Shoaf, SE; Wells, C1
Garcia-Prats, AJ; Hesseling, AC; Schaaf, HS; Thee, S; van der Laan, L1
Byun, JH; Kang, HR; Lee, EK; Park, JA; Shin, JY1
Baudin, E; Cellamare, M; Mitnick, CD; Trippa, L; Ventz, S1
Dedicoat, M1
Akkerman, OW; Alffenaar, JC; Anthony, RM; Cobelens, FG; Grobusch, MP; Heysell, S; Tiberi, S; Van Soolingen, D1
Wallis, RS1
Centis, R; D'Ambrosio, L; Fuentes, Z; Migliori, GB; Sotgiu, G; Tiberi, S; Zumla, A1
Bauer, TT; Bettermann, G; Krieger, D; Mauch, H; Rüssmann, H; Schönfeld, N; Vesenbeckh, S1
Bianchini, S; Bosis, S; Esposito, S; Migliori, GB; Principi, N; Tadolini, M1
Hanaki, E; Hayashi, M; Matsumoto, M1
Gao, F; Hu, M; Zheng, C1
Cooke, G; Fortunak, J; Gotham, D; Hill, A; Khoo, S; Nytko, FE; Pozniak, A1
Centis, R; D'Ambrosio, L; Esposito, S; Migliori, GB; Pontali, E; Sotgiu, G; Tadolini, M; Tiberi, S1
Sharma, DC1
Brzezinski, A; Milstein, M; Mitnick, CD; Varaine, F1
Geiter, LJ; Gupta, R; Hafkin, J; Hittel, N; Wells, CD1
Dass, R; Hettle, R; Wirth, D1
Anderson, RF; Blaser, A; Chatelain, E; Denny, WA; Franzblau, SG; Launay, D; Ma, Z; Maes, L; Palmer, BD; Shinde, SS; Thompson, AM; Wan, B; Wang, Y1
Ahmed, Z; Bhagat, A; Kour, G; Singh, PP1
Dong, L; Fu, Y; Huang, H; Huo, F; Jing, W; Li, Y; Ma, Y; Pang, Y; Zhao, L; Zong, Z1
Gupta, R; Hafkin, J; Hittel, N; Martin, A2
Akkerman, O; Alffenaar, JW; Amale, R; Centis, R; D'Ambrosio, L; Ganatra, S; Maryandyshev, A; Migliori, GB; Mullerpattan, J; Pontali, E; Sadutshang, TD; Sotgiu, G; Tiberi, S; Topgyal, S; Udwadia, ZF1
Avaliani, Z; Ferlazzo, G; Hayrapetyan, A; Hewison, C; Jonckheere, S; Khaidarkhanova, Z; Lachenal, N; Mohr, E; Sinha, A; Skrahina, A; Vambe, D; Varaine, F; Vasilyeva, I1
Jo, KW; Nam, GB; Shim, TS; Yoon, HY1
Kabra, SK; Lodha, R; Mukherjee, A1
Chang, KC; Cox, H; Dheda, K; Esmail, A; Lange, C; Wasserman, S1
Cox, V; Furin, J; Lessem, E1
Dowdy, D; Merritt, MW; Taylor, H; von Delft, A; Zwerling, A1
Cox, H; Cox, V; Ditiu, L; Furin, J; Garcia-Prats, A; Koenig, S; Lessem, E; Nathavitharana, R; Reuter, A; Seddon, JA; Stillo, J; Tisile, P; von Delft, A; von Delft, D1
Hwang, SH; Jeon, D; Kang, B; Kang, H; Koh, WJ; Lee, T; Mok, J; Park, JS; Yim, JJ1
Barkane, L; Gupta, R; Hittel, N; Kuksa, L1
Aarti, C; Barbabosa-Pliego, A; Khusro, A; Salem, AZM1
Cox, V; Furin, J1
Barkane, L; Caumes, E; Fréchet-Jachym, M; Guglielmetti, L; Kuksa, L; Le Dû, D; Marigot-Outtandy, D; Robert, J; Veziris, N; Yazdanpanah, Y1
Akkerman, OW; Alffenaar, JW; Bolhuis, MS; de Lange, WCM; de Vries, G; de Zwaan, R; Dedicoat, M; Frijlink, HW; Gajraj, R; Grasmeijer, F; Hagedoorn, P; Kerstjens, HAM; Smith, G; van der Werf, TS; van Soolingen, D1
Migliori, GB; Tadolini, M; Tiberi, S1
Cox, H; De Avezedo, V; Egazaryan, L; Ferlazzo, G; Furin, J; Hewison, C; Hughes, J; Isaakidis, P; Jonckheere, S; Kalon, S; Khachatryan, N; Laxmeshwar, C; Mohr, E; Shroufi, A1
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Spanevello, A; Visca, D1
Fujiwara, M; Hariguchi, N; Kawasaki, M; Liu, Y; Matsumoto, M1
Hun Choe, Y; Kim, CT; Kim, HR; Kim, TO; Ko, YC; Kwon, YS; Shin, HJ1
Uplekar, M1
Brigden, G; Cox, V; Crespo, RH; Furin, J; Lessem, E; Lynch, S; Rich, ML; Waning, B1
Falzon, D; Halleux, CM; Jaramillo, E; Merle, C; Mirzayev, F; Olliaro, P; Weyer, K1
Hauser, J; Jaramillo, E; Kuwana, R; Masini, T; Nhat Linh, N1
Chang, KC; Chau, CH; Lam, FM; Law, WS; Lee, SN; Leung, CC; Leung, EC; Leung, WM; Mok, TY; Tai, LB; Yew, WW1
Ade, S; Alikhanova, N; Benedetti, G; Cox, H; Daniels, J; De Azevedo, V; Edwards, J; Ferlazzo, G; Furin, J; Hughes, J; Isaakidis, P; Kock, Y; Mohr, E; Reuter, A; Shroufi, A; Steele, SJ; Trivino Duran, L1
Arbex, MA; D'Ambrosio, L; Dalcolmo, M; Duarte, R; Gaga, M; Migliori, GB; Munoz-Torrico, M; Rendon, A; Silva, DR; Tiberi, S; Visca, D; Zumla, A1
Bothamley, G; Burman, M; Guglielmetti, L; Kunst, H; Lange, C; Tiberi, S; Togonidze, T; Wejse, C1
Centis, R; D'Ambrosio, L; Migliori, GB; Pontali, E; Sotgiu, G; Spanevello, A; Tadolini, M; Tiberi, S; Visca, D1
Borroni, E; Cirillo, DM; Crook, DW; Cugnata, F; Davies, TJ; Fowler, PW; Gibertoni Cruz, AL; Grazian, C; Hoosdally, SJ; Peto, TEA; Rancoita, PMV; Walker, TM1
Flexner, C; Moss, DM; Owen, A; Podany, AT; Rajoli, RKR; Siccardi, M; Swindells, S1
Choi, H; Kim, KJ; Lee, SH; Yang, JS1
Bamrah Morris, S; Goswami, ND; Khan, AN; Lardizabal, AA1
Loganathan, U; Mukhopadhyay, B; Purwantini, E1
Perdigão, J; Portugal, I1
Fan, Q; Ming, WK; Yip, WY; You, JHS1
Li, Y; Sun, F; Zhang, W1
Balanag, V; Bielskiene, V; Cadena, E; Caoili, J; Cirule, A; Danilovits, M; Davidaviciene, E; Domente, L; Geiter, LJ; Gupta, R; Hafkin, J; Hittel, N; Lizarbe, V; Patientia, R; Petersen, C; Sanchez, E; Segura, P; Staples, S; Ticona, E; Variava, E; von Groote-Bidlingmaier, F; Wells, C; Yu, C1
Centis, R; Migliori, GB; Sotgiu, G1
Okumura, M; Yoshiyama, T1
Ahn, H; Ahn, JH; Cho, SN; Hahn, S; Jang, JY; Jeon, D; Jhun, BW; Jo, KW; Kang, YA; Kim, CK; Kim, DK; Kim, JS; Kim, SY; Kim, YR; Koh, WJ; Lee, JH; Lee, JY; Lee, M; Lee, SH; Lee, T; Mok, J; Park, JS; Shim, TS; Shin, S; Shin, SJ; Song, T; Won, HJ; Yim, JJ1
Köser, CU; Kranzer, K; Maurer, FP1
Laughon, BE; Lee, SFK; Lipman, M; McHugh, TD1
Arora, VK; Chopra, KK1
Khalid, UK; Mathuria, KK; Munjal, SK; Myneedu, VP; Puri, MM; Sarin, R; Singla, N; Singla, R; Verma, A; Vohra, V1
Cox, H; Furin, J; Loveday, M; Reuter, A; Seddon, JA1
Hoffmann, H; Hofmann-Thiel, S; Kranzer, K; Krieger, D; Merker, M; Niemann, S; Polsfuss, S; Rüssmann, H; Schönfeld, N1
Akkerman, O; Al-Marzouqi, NH; Aleksa, A; Alffenaar, JW; Arias-Guillén, M; Belilovski, E; Bernal, E; Boeree, MJ; Borisov, SE; Bruchfeld, J; Cadiñanos Loidi, J; Cai, Q; Caminero, JA; Cebrian Gallardo, JJ; Centis, R; Codecasa, LR; D'Ambrosio, L; Dalcolmo, M; Danila, E; Dara, M; Davidavičienė, E; Davies Forsman, L; De Los Rios Jefe, J; Denholm, J; Duarte, R; Elamin, SE; Ferrarese, M; Filippov, A; Ganatra, S; Garcia, A; García-García, JM; Gayoso, R; Giraldo Montoya, AM; Gomez Rosso, RG; Gualano, G; Hoefsloot, W; Ilievska-Poposka, B; Jonsson, J; Khimova, E; Kuksa, L; Kunst, H; Laniado-Laborín, R; Li, Y; Magis-Escurra, C; Manfrin, V; Manga, S; Marchese, V; Martínez Robles, E; Maryandyshev, A; Matteelli, A; Migliori, GB; Mullerpattan, JB; Munoz-Torrico, M; Mustafa Hamdan, H; Nieto Marcos, M; Noordin, NM; Palmero, DJ; Palmieri, F; Payen, MC; Piubello, A; Pontali, E; Pontarelli, A; Quirós, S; Rendon, A; Skrahina, A; Šmite, A; Solovic, I; Sotgiu, G; Souleymane, MB; Spanevello, A; Stošić, M; Tadolini, M; Tiberi, S; Udwadia, ZF; van den Boom, M; Vescovo, M; Viggiani, P; Visca, D; Zhurkin, D; Zignol, M1
De Azevedo, V; Ferlazzo, G; Hewison, C; Isaakidis, P; Mohr, E1
Alffenaar, JC; Marais, BJ; Sintchenko, V1
Daley, CL; Huh, HJ; Jeon, K; Jhun, BW; Kim, DH; Kim, SY; Koh, WJ; Kwon, OJ; Lee, NY; Moon, SM; Shin, SJ1
Bethunaickan, R; Chandramohan, Y; Padmanaban, V; Ranganathan, UD; Swaminathan, S; Tripathy, S1
Jeon, D; Jhun, BW; Kang, B; Kang, H; Koh, WJ; Kwak, N; Lee, T; Mok, J; Yim, JJ1
Sharma, S1
Karekar, SR; Marathe, PA1
Chen, SH; Ding, CZ; Gao, C; Huang, ZG; Li, J; Liu, KL; Luo, W; Peng, CT; Tao, X; Yu, LT1
Ceyssens, PJ; Coppee, JY; Legendre, R; Mathys, V; Sismeiro, O; Sury, A; Van den Bossche, A; Varet, H1
Caoili, JC; Chawla, P; Dartois, V; Dooley, KE; Ganatra, S; Gler, MT; Jain, SK; Peloquin, CA; Pieterse, L; Ritchie, B; Tornheim, JA; Tucker, EW; Udwadia, ZF; Zimmerman, MD1
Atwood, S; Bastard, M; Franke, MF; Hewison, C; Huerga, H; Khan, AJ; Khan, PY; Khan, U; Mitnick, CD; Rich, M; Seung, KJ; Varaine, F1
Dheda, K; Dooley, KE; Furin, J; Gumbo, T; Maartens, G; Murray, M; Nardell, EA; Warren, RM1
Dheda, K; Esmail, A; Limberis, J; Olayanju, O1
Ahmed, S; Aiylchiev, S; Alam, M; Bastard, M; Docteur, W; Franke, MF; Gottlieb, G; Hewison, C; Huerga, H; Islam, S; Khachatryan, N; Khan, P; Khan, U; Kotrikadze, T; Kumsa, A; Lecca, L; Melikyan, N; Mitnick, CD; Naing, YY; Oyewusi, L; Putri, FA; Rich, M; Seung, KJ; Tassew, YM; Wanjala, S; Yedilbayev, A1
Avaliani, Z; Bablishvili, N; Barbakadze, K; Benkeser, D; Blumberg, HM; Kempker, RR; Kipiani, M; Mikiashvili, L; Peloquin, CA; Zhao, Y1
Kudoh, S; Kurashima, A; Ogata, H; Ohta, K; Okumura, M; Yoshimori, K; Yoshiyama, T1
Gandhi, S; Shah, I; Shetty, NS1
Afriat-Jurnou, L; Ahmed, FH; Almeida, DV; Aung, HL; Beatson, SA; Cook, GM; Forde, BM; Greening, C; Hards, K; Harold, LK; Jackson, CJ; Lee, BM; Mohamed, AE; Nuermberger, EL; Pidot, SJ; Stinear, TP; Taylor, MC; West, NP1
Farhat, M; Kadura, S; King, N; Köser, CU; Nakhoul, M; Theron, G; Zhu, H1
Jeon, D; Jo, KW; Kang, H; Shim, TS; Yim, JJ1
Alffenaar, JC; Anthony, RM; Bañuls, AL; Cao, TTH; Nguyen, NV; Nguyen, TVA; Nguyen, VAT; Vu, DH1
Jeon, D; Jo, KW; Kang, H; Lee, HH; Shim, TS; Yim, JJ1
Chander, J; Kaur, M; Mohan, N; Saini, V; Singhal, L1
Ader, F; Chiesi, S; Dominguez, J; Eimer, J; Guglielmetti, L; Masini, T; Robert, J; Varaine, F; Veziris, N1
Beko, B; Cox, H; Daniels, J; De Avezedo, V; Ferlazzo, G; Furin, J; Hughes, J; Isaakidis, P; Kock, Y; Makhanda, G; Mohr-Holland, E; Reuter, A; Trivino Duran, L1
Aono, A; Kato, S; Mitarai, S; Ohta, K; Okumura, M; Takaki, A; Yoshiyama, T1
Mathema, B; O'Donnell, M1
Avihingsanon, A; Borrell, S; Böttger, EC; Collantes, J; Egger, M; Fenner, L; Gagneux, S; Hömke, R; Keller, PM; Loiseau, C; Reichmuth, ML; Reinhard, M; Sander, P; Wilkinson, RJ; Yotebieng, M; Zürcher, K1
Alikhanova, N; Barbova, A; Battaglia, S; Cabibbe, AM; Cirillo, DM; Dean, AS; Groenheit, R; Ismail, N; Meehan, CJ; Mostofa Kamal, SM; Niemann, S; Rigouts, L; Skrahina, A; Spitaleri, A; Tahseen, S; Utpatel, C; Zignol, M1
Boyd, BJ; Clulow, AJ; Hawley, A; Pham, AC; Ramirez, G; Salim, M1
Bashiri, G; Ioerger, T; Lanoix, JP; Lee, J; Li, SY; Nuermberger, E; Rifat, D; Sacchettini, J; Shah, K1
Coutisson, S; Dalal, A; Das, M; Ferlazzo, G; Hossain, FN; Isaakidis, P; Kalon, S; Lachenal, N; Laxmeshwar, C; Mamnoon, F; Mansoor, H; Mathur, T; Meneguim, AC; Paryani, R; Ravi, S; Singh, P1
Jeon, D; Kang, H; Kwon, YS; Shim, TS; Yim, JJ1
Gibiansky, E; Mallikaarjun, S; Wang, X1
Breitscheidel, L; Ghosh, S; Hafkin, J; Hittel, N; Lazarevic, N; Martin, A1
Chopra, V; Gupta, A1
Al-Shaer, MH; Alghamdi, WA; Barbakadze, K; Kempker, RR; Kipiani, M; Mikiashvili, L; Peloquin, CA1
Auchynka, V; Charnysh, I; Hurevich, H; Katovich, D; Klimuk, D; Kumar, AMV; Sereda, Y; Setkina, S; Skrahin, A; Skrahina, A; Solodovnikova, V; Yedilbayev, A1
Auchynka, V; Hurevich, H; Katovich, D; Kumar, AMV; Sereda, Y; Setkina, S; Skrahin, A; Skrahina, A; Solodovnikova, V; Yedilbayev, A1
Bax, HI; de Steenwinkel, JEM; Keutzer, L; Pieterman, ED; Simonsson, USH; van den Berg, S; van der Meijden, A; Wang, H; Zimmerman, MD1
Comins, K; Conradie, F; Cramer, YS; De Los Rios, J; Diacon, AH; Donahue, K; Dooley, KE; Hafner, R; Lama, JR; Maartens, G; Moran, L; Morganroth, J; Rosenkranz, SL; Shenje, J; von Groote-Bidlingmaier, F1
Acharya, S; Chavan, V; Das, M; Dhakulkar, S; Ferlazzo, G; Isaakidis, P; Iyer, A; Kalon, S; Mansoor, H; Meneguim, AC; Oswal, V; Ravi, S; Rebello, L; Shah, D; Sutar, N; Thakur, HP; Vengurlekar, D1
Bacchetti, P; Dheda, K; Esmail, A; Gandhi, M; Gerona, R; Huo, S; Metcalfe, J; Reckers, A1
Adenov, MM; Algozhin, YZ; Berikova, EA; Issayeva, AM; Maretbayeva, SM; Rakisheva, AS; Rich, ML; Seung, KJ; Stambekova, AT; Yedilbayev, A; Yeraliyeva, LT1
Hwang, H; Jeon, D; Kang, H; Kwon, YS; Shim, TS; Yim, JJ1
Acquah, R; Daniels, J; Furin, J; Loveday, M; Mohr-Holland, E; Mudaly, V; Reuter, A1
Kashiyama, E; Kim, S; Masuda, M; Sasabe, H; Sasahara, K; Sasaki, T; Shibata, M; Takeuchi, K; Umehara, K1
Bao, J; Cheng, Q; Fan, J; He, P; He, W; Li, Y; Liu, C; Liu, D; Ma, A; Song, Y; Zhao, B; Zhao, Y1
Campino, S; Clark, TG; Gomes, P; Gómez-González, PJ; Hibberd, ML; Napier, G; Perdigao, J; Phelan, JE; Portugal, I; Puyen, ZM; Santos-Lazaro, D; Viveiros, M1
Hafkin, J; Karlsson, MO; Mallikaarjun, S; Sasaki, T; Svensson, EM; Wang, X; Wang, Y1
Kumari, D; Perveen, S; Sharma, R; Singh, K1
Adenov, M; Adnan, S; Ahmed, S; Bastard, M; Coutisson, S; Danielyan, N; Franke, MF; Hewison, C; Huerga, H; Islam, S; Janmohamed, A; Kamene Kimenye, M; Karakozian, H; Khan, P; Khan, U; Kholikulov, B; Kirakosyan, O; Krisnanda, A; Kumsa, A; Lachenal, N; Leblanc, G; Lecca, L; Mamsa, S; Melikyan, N; Mitnick, CD; Nkuebe, M; Osso, E; Padayachee, S; Rich, ML; Seung, KJ; Thit, P; Varaine, F1
Bax, HI; De Steenwinkel, JEM; Lenaerts, A; Mudde, SE; Upton, AM1
Antony, S; Bodhanwala, M; Jaiswal, A; Parmar, M; Sachdeva, KS; Salve, J; Shah, D; Shah, I; Tipre, P1
Ahmed, S; Bastard, M; Franke, MF; Grium Tefera, D; Hewison, C; Holtzman, D; Huerga, H; Islam, S; Jacques Leblanc, G; Khan, PY; Khan, U; Kumsa, A; Lachenal, N; Leonovich, O; Mamsa, S; Manzur-Ul-Alam, M; Melikyan, N; Mitnick, CD; Myint, Z; Osso, E; Padayachee, S; Rafi Siddiqui, M; Rashitov, M; Rich, ML; Salahuddin, N; Salia, G; Sánchez, E; Serobyan, A; Seung, KJ; Varaine, F; Vetushko, D; Yeghiazaryan, L1
Carr, W; Converse, PJ; Dartois, V; Dooley, KE; Garcia, A; Kurbatova, E; Nuermberger, EL; Stout, JE; Tasneen, R; Vernon, AA; Zimmerman, MD1
De Leon, A; Frias, M; Garcia-Prats, AJ; Gler, MT; Hafkin, J; Hesseling, AC; Malikaarjun, S; Schaaf, HS; van der Laan, L1
Duong, TV; Nguyen, HT; Taylor, LS1
De Los Rios, J; Diacon, AH; Dooley, KE; Karlsson, MO; Maartens, G; Shenje, J; Svensson, EM; Tanneau, L; Upton, CM; Wiesner, L1
Cramer, YS; Diacon, AH; Dooley, KE; Karlsson, MO; Maartens, G; Morganroth, J; Rosenkranz, SL; Shenje, J; Svensson, EM; Tanneau, L; Upton, CM1
Apolisi, I; Beko, B; Cengani, L; Cox, H; Daniels, J; Fatshe, S; Furin, J; Gumede, N; Joseph, K; Mathee, S; Maugans, C; Memani, B; Reuter, A; Tyeku, N1
Andersen, ÅB; Dahl, VN; Guglielmetti, L; Holmgaard, FB; Lillebaek, T; Wejse, C1
Millard, J; Nimmo, C; O'Donnell, M; Rimmer, S1
Alghamdi, WA; Alshaer, MH; Avaliani, Z; Barbakadze, K; Benkeser, D; Blumberg, HM; Jin, Y; Kempker, RR; Kipiani, M; Maranchick, NF; Mikiashvili, L; Peloquin, CA1

Reviews

43 review(s) available for oxazoles and opc-67683

ArticleYear
Advances in the treatment of tuberculosis.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Adamantane; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Drugs, Investigational; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin; Treatment Refusal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2007
OPC-67683.
    Tuberculosis (Edinburgh, Scotland), 2008, Volume: 88, Issue:2

    Topics: Animals; Antitubercular Agents; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis

2008
New anti-tuberculosis drugs with novel mechanisms of action.
    Current medicinal chemistry, 2008, Volume: 15, Issue:19

    Topics: Adamantane; Animals; Antitubercular Agents; Diarylquinolines; Drug Design; Drug Resistance, Multiple, Bacterial; Ethylenediamines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Quinolines; Structure-Activity Relationship; Tuberculosis, Pulmonary

2008
[Tuberculosis: new treatment options and updated recommendations].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:14

    Topics: Antitubercular Agents; Aza Compounds; Cross-Sectional Studies; Diagnosis, Differential; Diarylquinolines; Fluoroquinolones; Germany; Humans; Moxifloxacin; Nitroimidazoles; Oxazoles; Prognosis; Quinolines; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant

2013
An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds.
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:22

    Topics: Anti-HIV Agents; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Design; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Structure-Activity Relationship; Tuberculosis, Multidrug-Resistant

2013
Tuberculosis: clinical trials and new drug regimens.
    Current opinion in pulmonary medicine, 2014, Volume: 20, Issue:3

    Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant

2014
Delamanid: first global approval.
    Drugs, 2014, Volume: 74, Issue:9

    Topics: Antitubercular Agents; Drug Approval; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2014
Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:2

    Topics: Antitubercular Agents; Clinical Trials as Topic; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2015
Delamanid: a review of its use in patients with multidrug-resistant tuberculosis.
    Drugs, 2015, Volume: 75, Issue:1

    Topics: Antitubercular Agents; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2015
Novel drugs against tuberculosis: a clinician's perspective.
    The European respiratory journal, 2015, Volume: 45, Issue:4

    Topics: Adamantane; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarylquinolines; Drug Therapy, Combination; Ethylenediamines; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Nitroimidazoles; Oxazoles; Oxazolidinones; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2015
Tuberculosis treatment and drug regimens.
    Cold Spring Harbor perspectives in medicine, 2015, Jan-08, Volume: 5, Issue:5

    Topics: Antitubercular Agents; China; Diarylquinolines; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; USSR

2015
Delamanid (OPC-67683) for treatment of multi-drug-resistant tuberculosis.
    Expert review of anti-infective therapy, 2015, Volume: 13, Issue:3

    Topics: Adult; Antitubercular Agents; Europe; Extensively Drug-Resistant Tuberculosis; Humans; Japan; Mycobacterium tuberculosis; Mycolic Acids; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; World Health Organization

2015
Profile of delamanid for the treatment of multidrug-resistant tuberculosis.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antitubercular Agents; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Long QT Syndrome; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Risk Assessment; Risk Factors; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2015
Delamanid for the treatment of pulmonary multidrug-resistant tuberculosis.
    Drugs of today (Barcelona, Spain : 1998), 2015, Volume: 51, Issue:2

    Topics: Antitubercular Agents; Drug Interactions; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2015
Access to new medications for the treatment of drug-resistant tuberculosis: patient, provider and community perspectives.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015, Volume: 32

    Topics: Antitubercular Agents; Compassionate Use Trials; Diarylquinolines; Health Services Accessibility; Humans; Linezolid; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Vulnerable Populations

2015
Bedaquiline and delamanid in tuberculosis.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:15

    Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Interactions; Drug Resistance, Bacterial; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2015
Management of drug resistantTB in patients with HIV co-infection.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:18

    Topics: Antitubercular Agents; Coinfection; Diarylquinolines; Disease Management; Extensively Drug-Resistant Tuberculosis; HIV Infections; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; World Health Organization

2015
Challenges facing the drug discovery pipeline for non-tuberculous mycobacteria.
    Journal of medical microbiology, 2016, Volume: 65, Issue:1

    Topics: Adamantane; Aminopyridines; Anti-Bacterial Agents; Azepines; Benzamides; Clinical Trials as Topic; Diarylquinolines; Drug Discovery; Ethylenediamines; Fluoroquinolones; Humans; Minocycline; Mycobacterium Infections, Nontuberculous; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles; Piperazines; Spiro Compounds; Thiazines; Tigecycline; Uridine

2016
Biotransformation and bioactivation reactions - 2015 literature highlights.
    Drug metabolism reviews, 2016, Volume: 48, Issue:2

    Topics: Acetaminophen; Allylbenzene Derivatives; Aniline Compounds; Animals; Anisoles; Benzbromarone; Biotransformation; Humans; Imidazoles; Niacinamide; Nitroimidazoles; Nitrosamines; Oxazoles; Oxazolidinones; Peroxides; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Pyridones; Pyrimidinones; Thiophenes; Triazoles

2016
Adverse effects of oral second-line antituberculosis drugs in children.
    Expert opinion on drug safety, 2016, Volume: 15, Issue:10

    Topics: Age Factors; Antitubercular Agents; Child; Diarylquinolines; Dose-Response Relationship, Drug; HIV Infections; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Individualizing management of extensively drug-resistant tuberculosis: diagnostics, treatment, and biomarkers.
    Expert review of anti-infective therapy, 2017, Volume: 15, Issue:1

    Topics: Antitubercular Agents; Biomarkers; Clinical Trials as Topic; Coinfection; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; HIV Infections; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Precision Medicine

2017
Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis: A case report and review of the literature.
    Medicine, 2016, Volume: 95, Issue:46

    Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Italy; Male; Nitroimidazoles; Oxazoles

2016
Use of bedaquiline and delamanid in diabetes patients: clinical and pharmacological considerations.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Aged; Animals; Antitubercular Agents; Arrhythmias, Cardiac; Comorbidity; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diarylquinolines; Drug Interactions; Drug Monitoring; Humans; Hypoglycemic Agents; Middle Aged; Nitroimidazoles; Oxazoles; Polypharmacy; Risk Assessment; Risk Factors; Tuberculosis

2016
Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review.
    International journal of molecular sciences, 2017, Feb-07, Volume: 18, Issue:2

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2017
(Re)moving the needle: prospects for all-oral treatment for multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, 12-01, Volume: 20, Issue:12

    Topics: Administration, Oral; Antitubercular Agents; Clinical Trials, Phase III as Topic; Diarylquinolines; Evidence-Based Medicine; Humans; Linezolid; Needles; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant

2016
Delamanid in the treatment of multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, 12-01, Volume: 20, Issue:12

    Topics: Antitubercular Agents; Clinical Protocols; Clinical Trials, Phase III as Topic; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Tuberculosis, Multidrug-Resistant

2016
Current therapies for the treatment of multidrug-resistant tuberculosis in children in India.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:15

    Topics: Antitubercular Agents; Child; Diarylquinolines; Drug Administration Schedule; Humans; India; Microbial Sensitivity Tests; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2017
Recent controversies about MDR and XDR-TB: Global implementation of the WHO shorter MDR-TB regimen and bedaquiline for all with MDR-TB?
    Respirology (Carlton, Vic.), 2018, Volume: 23, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; World Health Organization

2018
The devil we know: is the use of injectable agents for the treatment of MDR-TB justified?
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 11-01, Volume: 21, Issue:11

    Topics: Antitubercular Agents; Diarylquinolines; Health Services Accessibility; Human Rights; Humans; Injections; Nitroimidazoles; Oxazoles; Patient-Centered Care; Tuberculosis, Multidrug-Resistant

2017
Neoteric advancement in TB drugs and an overview on the anti-tubercular role of peptides through computational approaches.
    Microbial pathogenesis, 2018, Volume: 114

    Topics: Antitubercular Agents; Computational Biology; Diarylquinolines; Drug Design; Extensively Drug-Resistant Tuberculosis; Humans; Models, Molecular; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Peptides; Tuberculosis; Tuberculosis, Multidrug-Resistant; World Health Organization

2018
Multi and extensively drug-resistant pulmonary tuberculosis: advances in diagnosis and management.
    Current opinion in pulmonary medicine, 2018, Volume: 24, Issue:3

    Topics: Adolescent; Antitubercular Agents; Child; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2018
New and repurposed drugs to treat multidrug- and extensively drug-resistant tuberculosis.
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2018, Volume: 44, Issue:2

    Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Repositioning; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles

2018
Combined treatment of drug-resistant tuberculosis with bedaquiline and delamanid: a systematic review.
    The European respiratory journal, 2018, Volume: 52, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2018
Genetics and roadblocks of drug resistant tuberculosis.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2019, Volume: 72

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Epistasis, Genetic; Humans; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Phylogeny; Tuberculosis, Multidrug-Resistant

2019
Bedaquiline and delamanid in the treatment of multidrug-resistant tuberculosis: Promising but challenging.
    Drug development research, 2019, Volume: 80, Issue:1

    Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Electrocardiography; Humans; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2019
New drugs to treat difficult tuberculous and nontuberculous mycobacterial pulmonary disease.
    Current opinion in pulmonary medicine, 2019, Volume: 25, Issue:3

    Topics: Amikacin; Anti-Bacterial Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Liposomes; Lung Diseases; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Nitroimidazoles; Oxazoles

2019
The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis.
    The Lancet. Respiratory medicine, 2019, Volume: 7, Issue:9

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Linezolid; Nitroimidazoles; Oxazoles; Periodicals as Topic; Pulmonary Medicine; Societies, Medical; Tuberculosis; Tuberculosis, Multidrug-Resistant

2019
Systematic review of mutations associated with resistance to the new and repurposed Mycobacterium tuberculosis drugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid.
    The Journal of antimicrobial chemotherapy, 2020, 08-01, Volume: 75, Issue:8

    Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Linezolid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pharmaceutical Preparations; Tuberculosis, Multidrug-Resistant

2020
Delamanid Resistance: Update and Clinical Management.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 12-15, Volume: 71, Issue:12

    Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2020
Bedaquiline and delamanid for drug-resistant tuberculosis: a clinician's perspective.
    Future microbiology, 2020, Volume: 15

    Topics: Antitubercular Agents; Child; Clinical Trials as Topic; Diarylquinolines; Drug Therapy, Combination; Female; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pregnancy; Tuberculosis, Multidrug-Resistant

2020
Evolution of newer regimens in TB from RNTCP to NTEP.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:4S

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary

2020
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin

2022
Efficacy and Tolerability of Concomitant Use of Bedaquiline and Delamanid for Multidrug- and Extensively Drug-Resistant Tuberculosis: A Systematic Review and Meta-Analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 04-03, Volume: 76, Issue:7

    Topics: Antitubercular Agents; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2023

Trials

14 trial(s) available for oxazoles and opc-67683

ArticleYear
Early bactericidal activity of delamanid (OPC-67683) in smear-positive pulmonary tuberculosis patients.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2011, Volume: 15, Issue:7

    Topics: Adolescent; Adult; Antitubercular Agents; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome; Tuberculosis, Pulmonary; Young Adult

2011
Delamanid for multidrug-resistant pulmonary tuberculosis.
    The New England journal of medicine, 2012, Jun-07, Volume: 366, Issue:23

    Topics: Adolescent; Adult; Antitubercular Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Survival Analysis; Tuberculosis, Multidrug-Resistant; Young Adult

2012
Clinical benefit of delamanid (OPC-67683) in the treatment of multidrug-resistant tuberculosis patients in China.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Antitubercular Agents; China; Double-Blind Method; Female; Humans; Male; Mental Disorders; Middle Aged; Nitroimidazoles; Oxazoles; Placebo Effect; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2013
Long-term mortality assessment of multidrug-resistant tuberculosis patients treated with delamanid.
    The European respiratory journal, 2015, Volume: 45, Issue:5

    Topics: Biomarkers; Follow-Up Studies; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2015
Delamanid for Extensively Drug-Resistant Tuberculosis.
    The New England journal of medicine, 2015, Jul-16, Volume: 373, Issue:3

    Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome

2015
Simultaneous quantitation of delamanid (OPC-67683) and its eight metabolites in human plasma using UHPLC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Oct-01, Volume: 1002

    Topics: Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Limit of Detection; Nitroimidazoles; Oxazoles; Placebos; Reproducibility of Results; Tandem Mass Spectrometry

2015
Building clinical trial capacity to develop a new treatment for multidrug-resistant tuberculosis.
    Bulletin of the World Health Organization, 2016, Feb-01, Volume: 94, Issue:2

    Topics: Antitubercular Agents; Capacity Building; Clinical Protocols; Documentation; Drug Approval; Humans; International Cooperation; Nitroimidazoles; Oxazoles; Research Design; Tuberculosis, Multidrug-Resistant

2016
MIC of Delamanid (OPC-67683) against Mycobacterium tuberculosis Clinical Isolates and a Proposed Critical Concentration.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary

2016
Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10

    Topics: Adult; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Interactions; Ethambutol; Female; Healthy Volunteers; Humans; Isoniazid; Male; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin

2016
Efficacy and safety of delamanid in combination with an optimised background regimen for treatment of multidrug-resistant tuberculosis: a multicentre, randomised, double-blind, placebo-controlled, parallel group phase 3 trial.
    The Lancet. Respiratory medicine, 2019, Volume: 7, Issue:3

    Topics: Antitubercular Agents; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Isoniazid; Male; Middle Aged; Nitroimidazoles; Oxazoles; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2019
Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, m
    Trials, 2019, Jan-16, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Humans; Levofloxacin; Linezolid; Male; Middle Aged; Multicenter Studies as Topic; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Republic of Korea; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult

2019
QT effects of bedaquiline, delamanid, or both in patients with rifampicin-resistant tuberculosis: a phase 2, open-label, randomised, controlled trial.
    The Lancet. Infectious diseases, 2021, Volume: 21, Issue:7

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Nitroimidazoles; Oxazoles; Peru; Rifampin; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2021
Delamanid Added to an Optimized Background Regimen in Children with Multidrug-Resistant Tuberculosis: Results of a Phase I/II Clinical Trial.
    Antimicrobial agents and chemotherapy, 2022, 05-17, Volume: 66, Issue:5

    Topics: Adult; Antitubercular Agents; Child; Child, Preschool; Female; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2022
Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens.
    Clinical pharmacology and therapeutics, 2022, Volume: 112, Issue:4

    Topics: Diarylquinolines; Electrocardiography; Heart Rate; Humans; Nitroimidazoles; Oxazoles

2022

Other Studies

146 other study(ies) available for oxazoles and opc-67683

ArticleYear
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
    PLoS medicine, 2006, Volume: 3, Issue:11

    Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis

2006
Bactericidal activity of OPC-67683 against drug-tolerant Mycobacterium tuberculosis.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:5

    Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Time Factors

2007
[Recent progress in mycobacteriology].
    Kekkaku : [Tuberculosis], 2007, Volume: 82, Issue:10

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Bacteriology; DNA-Binding Proteins; Drug Design; Humans; Immunoenzyme Techniques; Japan; Mice; Minisatellite Repeats; Molecular Epidemiology; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Serologic Tests; Tuberculosis Vaccines; Tuberculosis, Pulmonary

2007
Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824.
    Bioorganic & medicinal chemistry letters, 2008, Apr-01, Volume: 18, Issue:7

    Topics: Antitubercular Agents; Crystallography, X-Ray; Drug Resistance, Bacterial; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Stereoisomerism; Structure-Activity Relationship

2008
[Some new antitubercular agents].
    Revue medicale suisse, 2008, Mar-19, Volume: 4, Issue:149

    Topics: Acetamides; Antitubercular Agents; Diarylquinolines; Humans; Linezolid; Nitroimidazoles; Oxazoles; Oxazolidinones; Quinolines

2008
A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:5

    Topics: Antitubercular Agents; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Microbial Viability; Molecular Structure; Mycobacterium bovis; Mycobacterium tuberculosis; Nitro Compounds; Nitroimidazoles; Oxazoles; Polycyclic Aromatic Hydrocarbons

2008
Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles.
    The FEBS journal, 2012, Volume: 279, Issue:1

    Topics: Antitubercular Agents; Cloning, Molecular; Flavins; Kinetics; Mycobacterium tuberculosis; Nitric Oxide; Nitroimidazoles; Nitroreductases; Oxazoles; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2012
Confronting multidrug-resistant tuberculosis.
    The New England journal of medicine, 2012, Jun-07, Volume: 366, Issue:23

    Topics: Antitubercular Agents; Epidemics; Female; Humans; Male; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2012
Trial watch: Novel antimicrobial fights TB resistance.
    Nature reviews. Drug discovery, 2012, Volume: 11, Issue:8

    Topics: Antitubercular Agents; Clinical Trials, Phase II as Topic; Drug Design; Humans; Medication Adherence; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2012
Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis.
    The European respiratory journal, 2013, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Antitubercular Agents; Drug Administration Schedule; Extensively Drug-Resistant Tuberculosis; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2013
Principles for designing future regimens for multidrug-resistant tuberculosis.
    Bulletin of the World Health Organization, 2014, Jan-01, Volume: 92, Issue:1

    Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Approval; Drug Design; Drug Resistance, Multiple, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2014
Improving the health of the tuberculosis drug pipeline.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:2

    Topics: Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Approval; Drug Discovery; Global Health; Humans; Nitroimidazoles; Oxazoles; Research Support as Topic; Tuberculosis

2014
ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: case study of compassionate delamanid use.
    The European respiratory journal, 2014, Volume: 44, Issue:3

    Topics: Antitubercular Agents; Child; Compassionate Use Trials; Disease Outbreaks; Europe; Extensively Drug-Resistant Tuberculosis; Humans; Italy; Male; Nitroimidazoles; Oxazoles; Program Development; Societies, Medical; Treatment Outcome; World Health Organization

2014
In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Animals; Antitubercular Agents; Caco-2 Cells; Cell Line, Tumor; Disease Models, Animal; Drug Interactions; Drug Resistance, Bacterial; Female; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Tuberculosis

2015
Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Animals; Antitubercular Agents; Clofazimine; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Female; Fluoroquinolones; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Pyrazinamide; Random Allocation; Tuberculosis

2015
Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:11

    Topics: Antitubercular Agents; Cells, Cultured; Cytochrome P-450 Enzyme System; Drug Interactions; Hepatocytes; Humans; Microsomes, Liver; Nitroimidazoles; Oxazoles; RNA, Messenger

2014
Access sought to tuberculosis drug from nutraceutical company.
    Nature medicine, 2015, Volume: 21, Issue:2

    Topics: Antitubercular Agents; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles

2015
Drug-resistance mechanisms and tuberculosis drugs.
    Lancet (London, England), 2015, Jan-24, Volume: 385, Issue:9965

    Topics: Antitubercular Agents; Diarylquinolines; Drug Approval; Humans; Mutation; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2015
Synthesis and structure-activity relationships for extended side chain analogues of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
    Journal of medicinal chemistry, 2015, Apr-09, Volume: 58, Issue:7

    Topics: Administration, Oral; Animals; Antitubercular Agents; Biological Availability; Chemistry Techniques, Synthetic; Chronic Disease; Disease Models, Animal; Humans; Male; Mice, Inbred BALB C; Mice, Inbred Strains; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Tuberculosis

2015
Cost effectiveness of treating multi-drug resistant tuberculosis by adding Deltyba™ to background regimens in Germany.
    Respiratory medicine, 2015, Volume: 109, Issue:5

    Topics: Adult; Antitubercular Agents; Cost-Benefit Analysis; Drug Costs; Female; Germany; Humans; Male; Markov Chains; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Failure; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2015
Determination of MIC distribution and epidemiological cutoff values for bedaquiline and delamanid in Mycobacterium tuberculosis using the MGIT 960 system equipped with TB eXiST.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:7

    Topics: Antitubercular Agents; Diarylquinolines; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Reference Values; Tuberculosis; Tuberculosis, Multidrug-Resistant

2015
Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:8

    Topics: Albumins; Animals; Antitubercular Agents; Biotransformation; Cytochrome P-450 Enzyme System; Dogs; Female; Humans; Hydroxylation; Isoenzymes; Ketones; Male; Mice; Mice, Inbred ICR; Nitroimidazoles; Oxazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2015
Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:8

    Topics: Animals; Antitubercular Agents; Biotransformation; Dogs; Half-Life; Humans; Hydrogen-Ion Concentration; Mice; Molecular Weight; Nitroimidazoles; Oxazoles; Rabbits; Rats; Serum Albumin; Temperature

2015
Classification of antituberculosis drugs: a new proposal based on the most recent evidence.
    The European respiratory journal, 2015, Volume: 46, Issue:4

    Topics: Antitubercular Agents; Carbapenems; Clavulanic Acid; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Infectious Disease Medicine; Linezolid; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization

2015
Compassionate and optimum use of new tuberculosis drugs.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:10

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Health Services Accessibility; Humans; Male; Nitroimidazoles; Oxazoles; Pneumonectomy

2015
Cost-effectiveness of incorporating bedaquiline into a treatment regimen for MDR/XDR-TB in Germany.
    The European respiratory journal, 2015, Volume: 46, Issue:6

    Topics: Antitubercular Agents; Computer Simulation; Cost-Benefit Analysis; Diarylquinolines; Drug Costs; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Germany; Humans; Markov Chains; Models, Economic; Nitroimidazoles; Oxazoles; Pyrazinamide; Tuberculosis, Multidrug-Resistant

2015
Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis.
    The New England journal of medicine, 2015, Nov-12, Volume: 373, Issue:20

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Male; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2015
Barriers to new drug development in respiratory disease.
    The European respiratory journal, 2016, Volume: 47, Issue:1

    Topics: Antitubercular Agents; Awards and Prizes; Diarylquinolines; Drug Discovery; Extensively Drug-Resistant Tuberculosis; Humans; Motivation; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Identification of patients who could benefit from bedaquiline or delamanid: a multisite MDR-TB cohort study.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:2

    Topics: Adult; Antitubercular Agents; Bacterial Load; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Eswatini; Female; Humans; Kenya; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Nitroimidazoles; Odds Ratio; Oxazoles; Patient Selection; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; USSR; Young Adult

2016
Reciprocity and Ethical Tuberculosis Treatment and Control.
    Journal of bioethical inquiry, 2016, Volume: 13, Issue:1

    Topics: Antitubercular Agents; Beneficence; Communicable Disease Control; Congresses as Topic; Diarylquinolines; Directly Observed Therapy; Ethical Analysis; Ethical Theory; Global Health; Humans; Moral Obligations; Nitroimidazoles; Oxazoles; Patient Isolation; Personal Autonomy; Pharmacovigilance; Poverty; Public Health; Social Justice; Social Responsibility; Tuberculosis, Laryngeal; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Virtues

2016
Delamanid and Bedaquiline Resistance in Mycobacterium tuberculosis Ancestral Beijing Genotype Causing Extensively Drug-Resistant Tuberculosis in a Tibetan Refugee.
    American journal of respiratory and critical care medicine, 2016, Feb-01, Volume: 193, Issue:3

    Topics: Adult; Antitubercular Agents; Beijing; Compassionate Use Trials; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Refugees; Tibet

2016
[New antitubercular agents are not where where we need them to be].
    Revue medicale suisse, 2015, Dec-16, Volume: 11, Issue:499

    Topics: Antitubercular Agents; Developing Countries; Diarylquinolines; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2015
Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis.
    Emerging infectious diseases, 2016, Volume: 22, Issue:3

    Topics: Antitubercular Agents; Diarylquinolines; Drug Approval; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Global Introduction of New Multidrug-Resistant Tuberculosis Drugs-Balancing Regulation with Urgent Patient Needs.
    Emerging infectious diseases, 2016, Volume: 22, Issue:3

    Topics: Antitubercular Agents; Diarylquinolines; Drug Prescriptions; Drug Resistance, Bacterial; Drug Utilization; Humans; Legislation, Drug; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Antitubercular Agent Delamanid and Metabolites as Substrates and Inhibitors of ABC and Solute Carrier Transporters.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Animals; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Cell Line; Drug Interactions; HEK293 Cells; Humans; Kidney Tubules, Proximal; Neoplasm Proteins; Nitroimidazoles; Octamer Transcription Factor-1; Organic Anion Transporters; Oxazoles; Solute Carrier Proteins; Swine; Tuberculosis, Multidrug-Resistant

2016
Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:6

    Topics: Antitubercular Agents; Automation, Laboratory; Colorimetry; Genes, Bacterial; Indicators and Reagents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Polymorphism, Genetic; Sequence Analysis, DNA; Xanthenes

2016
The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis.
    eLife, 2016, 05-24, Volume: 5

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Antitubercular Agents; Biotransformation; Disease Models, Animal; Drug Administration Schedule; Drug Dosage Calculations; Drug Repositioning; Female; Hormesis; Leishmania donovani; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oxazoles; Parasitic Sensitivity Tests; Treatment Outcome

2016
Access to new drugs and the global drug-resistant TB crisis: a case series from KwaZulu-Natal, South Africa.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:7

    Topics: Adult; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Health Services Accessibility; Humans; Male; Nitroimidazoles; Oxazoles; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2016
First case of extensively drug-resistant tuberculosis treated with both delamanid and bedaquiline.
    The European respiratory journal, 2016, Volume: 48, Issue:3

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Nitroimidazoles; Oxazoles

2016
Comparison of Effectiveness Between Delamanid and Bedaquiline Among Patients with Multidrug-Resistant Tuberculosis: A Markov Model Simulation Study.
    Clinical drug investigation, 2016, Volume: 36, Issue:11

    Topics: Aged; Diarylquinolines; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Tuberculosis, Multidrug-Resistant

2016
A Bayesian response-adaptive trial in tuberculosis: The endTB trial.
    Clinical trials (London, England), 2017, Volume: 14, Issue:1

    Topics: Adaptive Clinical Trials as Topic; Algorithms; Antitubercular Agents; Bayes Theorem; Computer Simulation; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2017
Using bedaquiline and delamanid in combination and safely.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2016, Volume: 20, Issue:10

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Global Health; Humans; Nitroimidazoles; Oxazoles; Tuberculosis

2016
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine.
    The European respiratory journal, 2016, Volume: 48, Issue:5

    Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Cardiac safety of extensively drug-resistant tuberculosis regimens including bedaquiline, delamanid and clofazimine.
    The European respiratory journal, 2016, Volume: 48, Issue:5

    Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2016
Applicability of the shorter 'Bangladesh regimen' in high multidrug-resistant tuberculosis settings.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 56

    Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Tuberculosis, Multidrug-Resistant; World Health Organization

2017
Is delamanid a potential agent in the treatment of diseases caused by Mycobacterium avium-intracellulare?
    The European respiratory journal, 2016, Volume: 48, Issue:6

    Topics: Antitubercular Agents; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Nitroimidazoles; Oxazoles

2016
Delamanid is not metabolized by Salmonella or human nitroreductases: A possible mechanism for the lack of mutagenicity.
    Regulatory toxicology and pharmacology : RTP, 2017, Volume: 84

    Topics: Antitubercular Agents; Bacterial Proteins; Biotransformation; DNA, Bacterial; Humans; Kinetics; Mutagenesis; Mutagenicity Tests; Nitroimidazoles; Nitroreductases; Oxazoles; Oxidation-Reduction; Risk Assessment; Salmonella typhimurium; Substrate Specificity

2017
Estimated generic prices for novel treatments for drug-resistant tuberculosis.
    The Journal of antimicrobial chemotherapy, 2017, 04-01, Volume: 72, Issue:4

    Topics: Algorithms; Antitubercular Agents; Commerce; Diarylquinolines; Drug Costs; Drugs, Generic; Fluoroquinolones; Humans; Moxifloxacin; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2017
India plans to expand access to new tuberculosis drug.
    Lancet (London, England), 2017, 02-18, Volume: 389, Issue:10070

    Topics: Antitubercular Agents; Diarylquinolines; Health Services Accessibility; Humans; India; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2017
Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany.
    BMC health services research, 2017, 03-08, Volume: 17, Issue:1

    Topics: Adult; Antitubercular Agents; Clinical Protocols; Clinical Trials as Topic; Cost-Benefit Analysis; Diarylquinolines; Drug Costs; Drug Therapy, Combination; Female; Germany; Humans; Linezolid; Male; Nitroimidazoles; Observational Studies as Topic; Oxazoles; Quality-Adjusted Life Years; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2017
6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases.
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Animals; Antitubercular Agents; Chagas Disease; Disease Models, Animal; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Structure-Activity Relationship; Thiazoles; Tuberculosis

2017
Biopharmaceutic parameters, pharmacokinetics, transport and CYP-mediated drug interactions of IIIM-017: A novel nitroimidazooxazole analogue with anti-tuberculosis activity.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Aug-30, Volume: 106

    Topics: Animals; Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Computer Simulation; Drug Interactions; Humans; Mice, Inbred BALB C; Microsomes, Liver; Nitroimidazoles; Oxazoles

2017
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:10

    Topics: Antitubercular Agents; Beijing; China; Clofazimine; Diarylquinolines; DNA Gyrase; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Gatifloxacin; Humans; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles

2017
Early outcomes in MDR-TB and XDR-TB patients treated with delamanid under compassionate use.
    The European respiratory journal, 2017, Volume: 50, Issue:1

    Topics: Adolescent; Adult; Antitubercular Agents; Child; Communicable Disease Control; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Female; Global Health; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant; World Health Organization

2017
Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis.
    Emerging infectious diseases, 2017, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Tuberculosis, Pulmonary; Young Adult

2017
Six-Month Response to Delamanid Treatment in MDR TB Patients.
    Emerging infectious diseases, 2017, Volume: 23, Issue:10

    Topics: Adolescent; Antitubercular Agents; Female; Hepatitis C; HIV Infections; Humans; Male; Nitroimidazoles; Oxazoles; Retrospective Studies; Tuberculosis, Multidrug-Resistant

2017
Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 09-01, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Azithromycin; Child; Clarithromycin; Clofazimine; Diarylquinolines; Female; Fluoroquinolones; Follow-Up Studies; Humans; Lost to Follow-Up; Macrolides; Male; Middle Aged; Moxifloxacin; Mycobacterium Infections, Nontuberculous; Mycobacterium tuberculosis; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles; Retrospective Studies; Tuberculosis, Multidrug-Resistant; Young Adult

2017
Bedaquiline or delamanid for rifampin-resistant tuberculosis?
    The Lancet. Respiratory medicine, 2017, Volume: 5, Issue:10

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rifampin; Tuberculosis, Multidrug-Resistant

2017
Incorporating social justice and stigma in cost-effectiveness analysis: drug-resistant tuberculosis treatment.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 11-01, Volume: 21, Issue:11

    Topics: Antitubercular Agents; Cost-Benefit Analysis; Decision Trees; Diarylquinolines; Humans; Models, Theoretical; Nitroimidazoles; Oxazoles; Social Justice; Social Stigma; South Africa; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2017
Interim outcomes of delamanid for the treatment of MDR- and XDR-TB in South Korea.
    The Journal of antimicrobial chemotherapy, 2018, 02-01, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bacteriological Techniques; Drug-Related Side Effects and Adverse Reactions; Female; Hospitals; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2018
Final treatment outcomes of multidrug- and extensively drug-resistant tuberculosis patients in Latvia receiving delamanid-containing regimens.
    The European respiratory journal, 2017, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Extensively Drug-Resistant Tuberculosis; Female; Humans; Latvia; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2017
World Health Organization recommendations for multidrug-resistant tuberculosis: should different standards be applied?
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2017, 12-01, Volume: 21, Issue:12

    Topics: Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Humans; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; World Health Organization

2017
Safety and efficacy of exposure to bedaquiline-delamanid in multidrug-resistant tuberculosis: a case series from France and Latvia.
    The European respiratory journal, 2018, Volume: 51, Issue:3

    Topics: Adult; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; France; Humans; Latvia; Male; Nitroimidazoles; Oxazoles; Patient Safety; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2018
Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis.
    The European respiratory journal, 2018, Volume: 51, Issue:3

    Topics: Adult; Antitubercular Agents; Colistin; Diarylquinolines; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Male; Medication Adherence; Mycobacterium tuberculosis; Netherlands; Nitroimidazoles; Oxazoles; Patient Isolation; Phenotype; Trimethoprim, Sulfamethoxazole Drug Combination; United Kingdom

2018
Combining bedaquiline and delamanid to treat multidrug-resistant tuberculosis.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:5

    Topics: Armenia; Diarylquinolines; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; South Africa; Tuberculosis, Multidrug-Resistant

2018
Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South Africa: a retrospective cohort study.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:5

    Topics: Adult; Antitubercular Agents; Armenia; Arrhythmias, Cardiac; Cohort Studies; Diarylquinolines; Drug Therapy, Combination; HIV Infections; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; South Africa; Tuberculosis, Multidrug-Resistant

2018
Mechanisms of resistance to delamanid, a drug for Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2018, Volume: 108

    Topics: Antitubercular Agents; Bacterial Proteins; Chromatography, High Pressure Liquid; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; Genotype; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Oxazoles; Phenotype; Riboflavin

2018
Bedaquiline and delamanid for the treatment of multidrug-resistant tuberculosis: a multicentre cohort study in Korea.
    The European respiratory journal, 2018, Volume: 51, Issue:3

    Topics: Adult; Antitubercular Agents; Cohort Studies; Diarylquinolines; Drug Administration Schedule; Female; Geography; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant; World Health Organization

2018
Using new TB tools: global rhetoric and ground reality.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4

    Topics: Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2018
Global programmatic use of bedaquiline and delamanid for the treatment of multidrug-resistant tuberculosis.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 04-01, Volume: 22, Issue:4

    Topics: Antitubercular Agents; Diarylquinolines; Humans; Internationality; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2018
The World Health Organization global aDSM database: generating evidence on the safety of new treatment regimens for drug-resistant tuberculosis.
    The European respiratory journal, 2018, Volume: 51, Issue:3

    Topics: Antitubercular Agents; Communicable Disease Control; Databases, Factual; Diarylquinolines; Humans; Infectious Disease Medicine; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Patient Safety; Public Health; Rifampin; Tuberculosis, Multidrug-Resistant; World Health Organization

2018
Will regulatory issues continue to be a major barrier to access to bedaquiline and delamanid?
    The European respiratory journal, 2018, Volume: 51, Issue:3

    Topics: Antitubercular Agents; Diarylquinolines; Diffusion of Innovation; Drug and Narcotic Control; Drug Approval; Global Health; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2018
Early experience with delamanid-containing regimens in the treatment of complicated multidrug-resistant tuberculosis in Hong Kong.
    The European respiratory journal, 2018, Volume: 51, Issue:6

    Topics: Adult; Antitubercular Agents; Female; Hong Kong; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2018
Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa.
    The European respiratory journal, 2018, Volume: 51, Issue:6

    Topics: Adult; Antitubercular Agents; Female; Humans; Logistic Models; Male; Nitroimidazoles; Oxazoles; Retrospective Studies; Rifampin; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2018
QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.
    The European respiratory journal, 2018, Volume: 52, Issue:2

    Topics: Antitubercular Agents; Cardiotoxicity; Cross-Sectional Studies; Diarylquinolines; Electrocardiography; Europe; Humans; Internationality; Long QT Syndrome; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2018
Validating a 14-Drug Microtiter Plate Containing Bedaquiline and Delamanid for Large-Scale Research Susceptibility Testing of Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9

    Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Reproducibility of Results; Tuberculosis; Tuberculosis, Multidrug-Resistant

2018
Modelling the long-acting administration of anti-tuberculosis agents using PBPK: a proof of concept study.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2018, 08-01, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Antitubercular Agents; Diarylquinolines; Drug Administration Schedule; Drug Liberation; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Isoniazid; Latent Tuberculosis; Male; Middle Aged; Nitroimidazoles; Oxazoles; Proof of Concept Study; Rifampin; Treatment Outcome; Young Adult

2018
Delamanid, Bedaquiline, and Linezolid Minimum Inhibitory Concentration Distributions and Resistance-related Gene Mutations in Multidrug-resistant and Extensively Drug-resistant Tuberculosis in Korea.
    Annals of laboratory medicine, 2018, Volume: 38, Issue:6

    Topics: Antitubercular Agents; Diarylquinolines; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant

2018
Notes from the Field: Acquisition of Delamanid Under a Compassionate Use Program for Extensively Drug-Resistant Tuberculosis - United States, 2017.
    MMWR. Morbidity and mortality weekly report, 2018, Sep-07, Volume: 67, Issue:35

    Topics: Antitubercular Agents; Centers for Disease Control and Prevention, U.S.; Compassionate Use Trials; Extensively Drug-Resistant Tuberculosis; Health Services Accessibility; Humans; Nitroimidazoles; Oxazoles; United States

2018
Coenzyme F
    Journal of bacteriology, 2018, 12-01, Volume: 200, Issue:23

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Glucosephosphate Dehydrogenase; Ligases; Methanobacteriaceae; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Polyglutamic Acid; Recombinant Proteins; Riboflavin; Tetrahydrofolates

2018
Cost-effectiveness of bedaquiline or delamanid plus background regimen for multidrug-resistant tuberculosis in a high-income intermediate burden city of China.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 78

    Topics: Adult; Cost-Benefit Analysis; Diarylquinolines; Follow-Up Studies; Hong Kong; Humans; Middle Aged; Monte Carlo Method; Nitroimidazoles; Oxazoles; Quality-Adjusted Life Years; Retrospective Studies; Socioeconomic Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2019
Compassionate use of delamanid in combination with bedaquiline for the treatment of multidrug-resistant tuberculosis.
    The European respiratory journal, 2019, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Antitubercular Agents; Child; Compassionate Use Trials; Diarylquinolines; Drug Therapy, Combination; Female; HIV Infections; Humans; Internationality; Male; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Young Adult

2019
Delamanid: does it have a role in tuberculosis treatment?
    The Lancet. Respiratory medicine, 2019, Volume: 7, Issue:3

    Topics: Double-Blind Method; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2019
[EXPERIENCE OF USE OF NEW ANTI-TUBERCULOUS DRUG, DELAMANID IN MULTI- AND EXTENSIVELY DRUG RESISTANT TUBERCULOSIS CASES IN OUR HOSPITAL].
    Kekkaku : [Tuberculosis], 2016, Volume: 91, Issue:11-12

    Topics: Adult; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniazid; Male; Middle Aged; Nitroimidazoles; Oxazoles

2016
Delamanid (Deltyba°) and multidrug-resistant pulmonary tuberculosis.
    Prescrire international, 2017, Volume: 26, Issue:181

    Topics: Antitubercular Agents; Electrocardiography; Humans; Long QT Syndrome; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2017
'Those who cannot remember the past are condemned to repeat it': Drug-susceptibility testing for bedaquiline and delamanid.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 80S

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles

2019
Journey of tuberculosis control in India.
    The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Directly Observed Therapy; Goals; History, 20th Century; History, 21st Century; Humans; India; National Health Programs; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary

2019
Early efficacy and safety of Bedaquiline and Delamanid given together in a "Salvage Regimen" for treatment of drug-resistant tuberculosis.
    The Indian journal of tuberculosis, 2019, Volume: 66, Issue:1

    Topics: Adult; Cardiotoxicity; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Electrocardiography; Female; Humans; Imipenem; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Salvage Therapy; Sputum; Survival Rate; Tuberculosis, Multidrug-Resistant; Young Adult

2019
The STREAM trial: missed opportunities and lessons for future clinical trials.
    The Lancet. Infectious diseases, 2019, Volume: 19, Issue:4

    Topics: Antitubercular Agents; Deafness; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Time Factors; Tuberculosis, Multidrug-Resistant

2019
Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 09-13, Volume: 69, Issue:7

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome

2019
Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 83

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Male; Nitroimidazoles; Oxazoles; Pilot Projects; Tuberculosis; Tuberculosis, Multidrug-Resistant; World Health Organization

2019
Bedaquiline and delamanid in combination for treatment of drug-resistant tuberculosis.
    The Lancet. Infectious diseases, 2019, Volume: 19, Issue:5

    Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Drug Therapy, Combination; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2019
Acquired Drug Resistance: Recognizing the Potential of Repurposed Drugs.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 11-13, Volume: 69, Issue:11

    Topics: Diarylquinolines; Drug Resistance; Extensively Drug-Resistant Tuberculosis; Humans; Nitroimidazoles; Oxazoles

2019
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:8

    Topics: Anti-Bacterial Agents; Antitubercular Agents; Diarylquinolines; Humans; Macrolides; Microbial Sensitivity Tests; Mycobacterium abscessus; Mycobacterium avium Complex; Mycobacterium Infections, Nontuberculous; Mycobacterium kansasii; Nitroimidazoles; Nontuberculous Mycobacteria; Oxazoles

2019
In vitro interaction profiles of the new antitubercular drugs bedaquiline and delamanid with moxifloxacin against clinical Mycobacterium tuberculosis isolates.
    Journal of global antimicrobial resistance, 2019, Volume: 19

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazines; Oxazoles; Tuberculosis, Multidrug-Resistant; Xanthenes

2019
Final treatment outcomes of delamanid-containing regimens in patients with MDR-/XDR-TB in South Korea.
    The European respiratory journal, 2019, Volume: 54, Issue:5

    Topics: Adult; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2019
Undergraduate Medical Teaching: Time to integrate?
    The Journal of the Association of Physicians of India, 2018, Volume: 66, Issue:8

    Topics: Antitubercular Agents; Drug Approval; Education, Medical; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2018
Current Status of Delamanid in the Management of MDR Tuberculosis.
    The Journal of the Association of Physicians of India, 2018, Volume: 66, Issue:7

    Topics: Antitubercular Agents; Child; Female; Humans; India; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pregnancy; Tuberculosis, Multidrug-Resistant

2018
Discovery and evaluation of novel nitrodihydroimidazooxazoles as promising anti-tuberculosis agents.
    Bioorganic & medicinal chemistry letters, 2019, 09-01, Volume: 29, Issue:17

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Permeability; Solubility; Structure-Activity Relationship; Vero Cells

2019
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.
    Tuberculosis (Edinburgh, Scotland), 2019, Volume: 117

    Topics: Aerobiosis; Antitubercular Agents; Cell Wall; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; RNA, Bacterial; Sequence Analysis, RNA

2019
Delamanid Central Nervous System Pharmacokinetics in Tuberculous Meningitis in Rabbits and Humans.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:10

    Topics: Animals; Antitubercular Agents; Central Nervous System; Female; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Rabbits; Treatment Outcome; Tuberculosis, Meningeal; Tuberculosis, Multidrug-Resistant

2019
The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.
    BMC infectious diseases, 2019, Aug-20, Volume: 19, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Nitroimidazoles; Observational Studies as Topic; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2019
A regimen containing bedaquiline and delamanid compared to bedaquiline in patients with drug-resistant tuberculosis.
    The European respiratory journal, 2020, Volume: 55, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant

2020
Culture Conversion at 6 Months in Patients Receiving Delamanid-containing Regimens for the Treatment of Multidrug-resistant Tuberculosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 07-11, Volume: 71, Issue:2

    Topics: Antitubercular Agents; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2020
Clinical Outcomes Among Patients With Drug-resistant Tuberculosis Receiving Bedaquiline- or Delamanid-Containing Regimens.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 12-03, Volume: 71, Issue:9

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Georgia; Humans; Male; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant

2020
Treatment of multidrug-resistant pulmonary tuberculosis with delamanid based on Japanese guideline recommendations.
    Respiratory investigation, 2020, Volume: 58, Issue:2

    Topics: Adult; Antitubercular Agents; Drug Resistance, Multiple; Female; Humans; Japan; Male; Middle Aged; Nitroimidazoles; Oxazoles; Practice Guidelines as Topic; Tuberculosis, Pulmonary

2020
Bedaquiline and Delamanid in Children With XDR Tuberculosis: What is prolonged QTc?
    The Pediatric infectious disease journal, 2020, Volume: 39, Issue:6

    Topics: Adolescent; Antitubercular Agents; Child; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Sputum; Tomography, X-Ray Computed

2020
Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.
    PLoS pathogens, 2020, Volume: 16, Issue:2

    Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Oxazoles; Polymorphism, Genetic; Protein Engineering

2020
Interim treatment outcomes in multidrug-resistant tuberculosis using bedaquiline and/or delamanid in South Korea.
    Respiratory medicine, 2020, Volume: 167

    Topics: Age Factors; Aged; Body Mass Index; Diarylquinolines; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nitroimidazoles; Oxazoles; Republic of Korea; Retrospective Studies; Risk Factors; Safety; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary

2020
Interim treatment outcomes in multidrug-resistant tuberculosis patients treated sequentially with bedaquiline and delamanid.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 98

    Topics: Adult; Aged; Antitubercular Agents; Diarylquinolines; Female; Humans; Male; Middle Aged; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2020
An Experience with Delamanid in an XDR TB Case - Case Report.
    Infectious disorders drug targets, 2021, Volume: 21, Issue:4

    Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Male; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles

2021
Correspondence regarding "Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa".
    The European respiratory journal, 2020, Volume: 56, Issue:1

    Topics: Humans; Nitroimidazoles; Oxazoles; Retrospective Studies; Rifampin; South Africa; Tuberculosis, Multidrug-Resistant

2020
Multidrug Resistant Tuberculosis With Simultaneously Acquired Drug Resistance to Bedaquiline and Delamanid.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 12-16, Volume: 73, Issue:12

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2021
Operational Research on the Treatment of Drug-Resistant Tuberculosis: Exciting Results That Need to Be Protected.
    American journal of respiratory and critical care medicine, 2021, 01-01, Volume: 203, Issue:1

    Topics: Diarylquinolines; Humans; Nitroimidazoles; Operations Research; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant

2021
Natural Polymorphisms in Mycobacterium tuberculosis Conferring Resistance to Delamanid in Drug-Naive Patients.
    Antimicrobial agents and chemotherapy, 2020, 10-20, Volume: 64, Issue:11

    Topics: Africa; Antitubercular Agents; Asia; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pharmaceutical Preparations; South America; Tuberculosis, Multidrug-Resistant

2020
Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains.
    Journal of clinical microbiology, 2020, 10-21, Volume: 58, Issue:11

    Topics: Antitubercular Agents; Diarylquinolines; Genomics; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2020
Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration.
    Drug delivery and translational research, 2021, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; Cinnarizine; Humans; Liquid Crystals; Nitroimidazoles; Oxazoles; Rats; Solubility

2021
Mutations in
    Antimicrobial agents and chemotherapy, 2020, 12-16, Volume: 65, Issue:1

    Topics: Animals; Antitubercular Agents; Mice; Mutation; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles

2020
One Step Forward: Successful End-of-Treatment Outcomes of Patients With Drug-Resistant Tuberculosis Who Received Concomitant Bedaquiline and Delamanid in Mumbai, India.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 11-02, Volume: 73, Issue:9

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Humans; India; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult

2021
Concurrent use of bedaquiline and delamanid for the treatment of fluoroquinolone-resistant multidrug-resistant tuberculosis: a nationwide cohort study in South Korea.
    The European respiratory journal, 2021, Volume: 57, Issue:3

    Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Fluoroquinolones; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Republic of Korea; Tuberculosis, Multidrug-Resistant

2021
Population Pharmacokinetic Analysis of Delamanid in Patients with Pulmonary Multidrug-Resistant Tuberculosis.
    Antimicrobial agents and chemotherapy, 2020, 12-16, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Antitubercular Agents; Humans; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult

2020
Compassionate use of delamanid in adults and children for drug-resistant tuberculosis: 5-year update.
    The European respiratory journal, 2021, Volume: 57, Issue:5

    Topics: Adolescent; Adult; Antitubercular Agents; Child; Compassionate Use Trials; Humans; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2021
Pharmacokinetics of bedaquiline, delamanid and clofazimine in patients with multidrug-resistant tuberculosis.
    The Journal of antimicrobial chemotherapy, 2021, 03-12, Volume: 76, Issue:4

    Topics: Antitubercular Agents; Clofazimine; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant

2021
Effectiveness and safety of delamanid- or bedaquiline-containing regimens among children and adolescents with multidrug resistant or extensively drug resistant tuberculosis: A nationwide study from Belarus, 2015-19.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2021, Jan-14, Volume: 91, Issue:1

    Topics: Adolescent; Antitubercular Agents; Child; Cohort Studies; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Republic of Belarus

2021
Effectiveness and cardiovascular safety of delamanid-containing regimens in adults with multidrug-resistant or extensively drug-resistant tuberculosis: A nationwide cohort study from Belarus, 2016-18.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2021, Jan-14, Volume: 91, Issue:1

    Topics: Adult; Antitubercular Agents; Cohort Studies; Extensively Drug-Resistant Tuberculosis; Female; Humans; Male; Nitroimidazoles; Oxazoles; Republic of Belarus; Treatment Outcome

2021
Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model.
    The Journal of infectious diseases, 2021, 09-17, Volume: 224, Issue:6

    Topics: Animals; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Therapy, Combination; Linezolid; Mice; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Recurrence; Tuberculosis

2021
Treatment outcomes of children and adolescents receiving drug-resistant TB treatment in a routine TB programme, Mumbai, India.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Adolescent; Ambulatory Care Facilities; Antitubercular Agents; Child; Child, Preschool; Diarylquinolines; Extensively Drug-Resistant Tuberculosis; Female; Humans; India; Infant; Infant, Newborn; Male; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2021
Development and validation of a liquid chromatography-tandem mass spectrometry method for quantifying delamanid and its metabolite in small hair samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021, Apr-15, Volume: 1169

    Topics: Chromatography, Liquid; Hair; Humans; Limit of Detection; Linear Models; Nitroimidazoles; Oxazoles; Reproducibility of Results; Tandem Mass Spectrometry; Tuberculosis; Tuberculosis, Multidrug-Resistant

2021
Culture conversion at six months in patients receiving bedaquiline- and delamanid-containing regimens for the treatment of multidrug-resistant tuberculosis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 113 Suppl 1

    Topics: Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2021
Outcomes of Multidrug-Resistant Tuberculosis Treated With Bedaquiline or Delamanid.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 10-20, Volume: 73, Issue:8

    Topics: Antitubercular Agents; Cohort Studies; Diarylquinolines; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2021
Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients.
    The Pediatric infectious disease journal, 2021, 05-01, Volume: 40, Issue:5

    Topics: Adult; Antitubercular Agents; Child Health; Child, Preschool; Diarylquinolines; Female; Humans; Infant; Infant Health; Linezolid; Nitroimidazoles; Oxazoles; Pregnancy; Pregnancy Outcome; Pregnant Women; South Africa; Tuberculosis, Multidrug-Resistant; Young Adult

2021
Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis.
    Antimicrobial agents and chemotherapy, 2021, 07-16, Volume: 65, Issue:8

    Topics: Animals; Antitubercular Agents; Dogs; Humans; Mice; Models, Biological; Nitroimidazoles; Oxazoles; Rats; Tuberculosis

2021
Prevalence of Mycobacterium tuberculosis resistant to bedaquiline and delamanid in China.
    Journal of global antimicrobial resistance, 2021, Volume: 26

    Topics: China; Diarylquinolines; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Phylogeny; Prevalence; Retrospective Studies

2021
Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid.
    Scientific reports, 2021, 09-30, Volume: 11, Issue:1

    Topics: Antitubercular Agents; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Humans; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant; Whole Genome Sequencing

2021
Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis.
    Antimicrobial agents and chemotherapy, 2022, 02-15, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Humans; Infant; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2022
Safety of Treatment Regimens Containing Bedaquiline and Delamanid in the endTB Cohort.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 09-29, Volume: 75, Issue:6

    Topics: Antitubercular Agents; Diarylquinolines; Electrolytes; Humans; Linezolid; Nitroimidazoles; Oxazoles; Prospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2022
Delamanid or pretomanid? A Solomonic judgement!
    The Journal of antimicrobial chemotherapy, 2022, 03-31, Volume: 77, Issue:4

    Topics: Antitubercular Agents; Diarylquinolines; Humans; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2022
Feasibility of a "Salvage Regimen" Using Home-based Intravenous Meropenem Therapy With a Delamanid/Bedaquilline Containing Regimen in the Management of MDR/XDR Pediatric Tuberculosis.
    The Pediatric infectious disease journal, 2022, 05-01, Volume: 41, Issue:5

    Topics: Adolescent; Antitubercular Agents; Child; Extensively Drug-Resistant Tuberculosis; Feasibility Studies; Female; Humans; Male; Meropenem; Nitroimidazoles; Oxazoles; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant

2022
Safety and Effectiveness Outcomes From a 14-Country Cohort of Patients With Multi-Drug Resistant Tuberculosis Treated Concomitantly With Bedaquiline, Delamanid, and Other Second-Line Drugs.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 10-12, Volume: 75, Issue:8

    Topics: Antitubercular Agents; Clofazimine; Cohort Studies; Diarylquinolines; Electrolytes; Fluoroquinolones; Humans; Linezolid; Nitroimidazoles; Oxazoles; Prospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant

2022
Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
    Antimicrobial agents and chemotherapy, 2022, 04-19, Volume: 66, Issue:4

    Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Isoniazid; Mice; Mice, Inbred BALB C; Moxifloxacin; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifabutin; Tuberculosis

2022
Combining enabling formulation strategies to generate supersaturated solutions of delamanid: In situ salt formation during amorphous solid dispersion fabrication for more robust release profiles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 174

    Topics: Drug Liberation; Drug Stability; Nitroimidazoles; Oxazoles; Salts; Solubility; Water

2022
Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:8

    Topics: Adult; Albumins; Antitubercular Agents; Diarylquinolines; HIV Infections; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2022
[Expert consensus on clinical application of delamanid].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2022, Sep-12, Volume: 45, Issue:9

    Topics: Consensus; Humans; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2022
Pediatric delamanid treatment for children with rifampicin-resistant TB.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2022, 10-01, Volume: 26, Issue:10

    Topics: Antitubercular Agents; Child; Humans; Nitroimidazoles; Oxazoles; Rifampin; Tuberculosis, Multidrug-Resistant

2022
Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB.
    Emerging infectious diseases, 2023, Volume: 29, Issue:5

    Topics: Antitubercular Agents; Diarylquinolines; Female; Humans; Middle Aged; Nitroimidazoles; Oxazoles; Tuberculosis, Multidrug-Resistant

2023
The effect of anti-tuberculosis drug pharmacokinetics on QTc prolongation.
    International journal of antimicrobial agents, 2023, Volume: 62, Issue:4

    Topics: Adult; Antitubercular Agents; Diarylquinolines; Female; Humans; Long QT Syndrome; Male; Nitroimidazoles; Oxazoles; Prospective Studies; Tuberculosis, Multidrug-Resistant

2023