Page last updated: 2024-08-21

oxazoles and midazolam

oxazoles has been researched along with midazolam in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Brunner, EA; Cheng, SC1
Jensen, MS; Lambert, JD1
Cohen, AF; Dingemanse, J; Heizmann, P; Keesmaat, P; Kooyman, H; Massarella, J; Roncari, G; Schoemaker, RC; van Gerven, JM; Zell, M1
Cohen, AF; Schoemaker, RC; van Gerven, JM1
Albrecht, S; Hering, W; Ihmsen, H; Schüttler, J; Schwilden, H1
Bertino, JS; Gartung, AM; Liu, S; Ma, JD; Nafziger, AN; Rhodes, G1
Bertino, JS; Liu, S; Ma, JD; Nafziger, AN; Rhodes, G1
Cahn, AP; Georgiou, A; Harrell, AW; Hessel, EM; Marotti, M; Patel, A; Riddell, K; Taskar, KS; Taylor, M; Tracey, H; Wilson, R1
Abdulrasool, LI; Endres, CJ; Lee, A; Mayor, JG; Rustia, EL; Sun, H; Topletz-Erickson, A; Walker, L1

Trials

4 trial(s) available for oxazoles and midazolam

ArticleYear
Integrated pharmacokinetics and pharmacodynamics of Ro 48-8684, a new benzodiazepine, in comparison with midazolam during first administration to healthy male subjects.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:5

    Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Humans; Infusions, Intravenous; Male; Midazolam; Oxazoles; Placebos; Saccades

1997
[Pharmacokinetic-pharmacodynamic modeling in phase II of drug development. A comparative study with young and old volunteers with benzdiazepine as an example].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1999, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Algorithms; Anti-Anxiety Agents; Benzodiazepines; Cross-Over Studies; Female; Humans; Male; Midazolam; Models, Biological; Oxazoles

1999
The effect of oral pleconaril on hepatic cytochrome P450 3A activity in healthy adults using intravenous midazolam as a probe.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:1

    Topics: Administration, Oral; Adult; Antiviral Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Injections, Intravenous; Liver; Male; Midazolam; Oxadiazoles; Oxazoles

2006
Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Aged; Area Under Curve; Clarithromycin; Computer Simulation; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Erythromycin; Healthy Volunteers; Humans; Indazoles; Indoles; Itraconazole; Male; Microsomes, Liver; Midazolam; Middle Aged; Models, Biological; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Prospective Studies; Retrospective Studies; Young Adult

2020

Other Studies

5 other study(ies) available for oxazoles and midazolam

ArticleYear
Inducing anesthesia with a GABA analog, THIP.
    Anesthesiology, 1985, Volume: 63, Issue:2

    Topics: Analgesics; Anesthesia, Intravenous; Anesthetics; Animals; Benzodiazepines; gamma-Aminobutyric Acid; Isoxazoles; Ketamine; Male; Mice; Midazolam; Oxazoles; Rats; Rats, Inbred Strains; Sodium Oxybate; Time Factors

1985
Modulation of the responses to the GABA-mimetics, THIP and piperidine-4-sulphonic acid, by agents which interact with benzodiazepine receptors. An electrophysiological study on cultured mouse neurones.
    Neuropharmacology, 1984, Volume: 23, Issue:12A

    Topics: Animals; Benzodiazepines; Carbolines; Cells, Cultured; Convulsants; Electrophysiology; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Mice; Midazolam; Neurons; Oxazoles; Piperidines; Receptors, GABA-A

1984
Estimating potency for the Emax-model without attaining maximal effects.
    Journal of pharmacokinetics and biopharmaceutics, 1998, Volume: 26, Issue:5

    Topics: Adjuvants, Anesthesia; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Linear Models; Midazolam; Oxazoles; Pharmacology; Saccades; Toxicology

1998
Duration of pleconaril effect on cytochrome P450 3A activity in healthy adults using the oral biomarker midazolam.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:5

    Topics: Adult; Antiviral Agents; Area Under Curve; Cytochrome P-450 CYP3A; Enzyme Induction; Female; Half-Life; Humans; Hypnotics and Sedatives; Intestines; Liver; Male; Midazolam; Middle Aged; Oxadiazoles; Oxazoles

2006
Evaluation of Safety and Clinically Relevant Drug-Drug Interactions with Tucatinib in Healthy Volunteers.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:10

    Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Digoxin; Drug Interactions; Gemfibrozil; Healthy Volunteers; Humans; Itraconazole; Midazolam; Oxazoles; Pyridines; Quinazolines; Rifampin; Tolbutamide

2022