Page last updated: 2024-08-21

oxazoles and glycine

oxazoles has been researched along with glycine in 126 studies

Research

Studies (126)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (32.54)	18.7374
1990's	5 (3.97)	18.2507
2000's	59 (46.83)	29.6817
2010's	18 (14.29)	24.3611
2020's	3 (2.38)	2.80

Authors

Authors	Studies
Tucker, AN; Waddell, WJ	1
Berger, AE; Bloch, A; Grindey, GB; McPartland, RP; Neil, GL	1
Bogden, AE; Houchens, DP; Johnson, RK; Neil, GL; Ovejera, AA; Sheridan, MA	1
Holcenberg, JS	1
Berger, AE; Bhuyan, BK; Blowers, CL; Kuentzel, SL; Neil, GL	1
Baczysnkyj, L; Chidester, CG; Duchamp, DJ; Martin, DG; Mizsak, SA	1
Grahl-Nielsen, O; Movik, B	1
Belter, PA; Coleman, TA; Gerpheid, SA; Hanka, LJ; Martin, DG; Meyer, HF; Spieles, PR	1
Burgoyne, RD; Cambray-Deakin, MA; Foster, AC	1
Bruns, RF; Drummond, J; Johnson, G; Nickell, DG; Ortwine, DF; Welbaum, B	1
Byberg, JR; Curtis, DR; Falch, E; Gynther, BD; Hjeds, H; Krogsgaard-Larsen, P; Labouta, IM	1
Hjeds, H; Krogsgaard-Larsen, P; Sarhan, S; Schousboe, A; Seiler, N	1
Brehm, L; Curtis, DR; Falch, E; Johansen, JS; Krogsgaard-Larsen, P; Schaumburg, K	1
Braestrup, C; Krogsgaard-Larsen, P; Nielsen, M	1
Krogsgaard-Larsen, P; Schousboe, A; Wood, JD	1
Casanova, TG; Chu, C; Panetta, CA	1
Dietz, A; Hanka, LJ	1
Pétra, PH	1
Hasselblatt, A; Panten, U; Poser, W	1
Baudet, P; Otten, C; Rao, D	1
De Jersey, J; Kortt, AA; Zerner, B	1
Baranowski, T; Kochman, M	1
Allen, L; Meck, R; Yunis, A	1
Ellis, WW; Meck, RA; Reed, DJ	1
Allen, LM; Thornthwaite, JT	1
Allen, LM; Corrigan, MV; Meinking, T	1
Gardell, SJ; Tate, SS	1
Kozak, EM; Tate, SS	1
Curthoys, NP; Shapiro, RA	1
Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ	1
Simmonds, MA	1
Goebel, DJ; McReynolds, JS; Pourch, RG	1
Sarhan, S; Seiler, N	1
Bower, SG; Tso, JY; Zalkin, H	1
Bruno, S; McGovren, JP; Neil, GL; Penta, J; Poster, DS	1
Kizaki, H; Lui, MS; Weber, G	1
Chan, PJ; McGovren, JP; Neil, GL; Stewart, JC	1
Roberts, J; Rosenfeld, H	1
Kufe, DW; Loh, E	1
Biles, C; Martin, DG; Mizsak, SA	1
Persson, B	1
Cooney, DA; Kensler, TW; Reck, LJ	1
Brautigan, DL; MacDonald, JF; Orser, BA; Wang, LY	1
Katayama, I; Nishioka, K; Satoh, T; Yokozeki, H	1
Barbieri, R; Di Berardino, D; Lioi, MB; Santoro, A; Scarfì, MR; Ursini, MV; Zeni, O	1
Harris, RA; Martinez, LD; Mascia, MP; Wick, MJ	1
Cai, C; Hruby, VJ; Soloshonok, VA	1
Kamiya, A	1
Ahn, KH; Kim, SG; Kim, Y; Kim, YK; Ku, HY; Ku, JK; Son, HS	1
Johnston, D; Wang, J; Yeckel, MF; Zucker, RS	1
Arora, A; Choe, ES; Fibuch, EE; Liu, Z; Mao, L; Wang, JQ; Yang, L; Zhang, G	1
Biller, SA; Cap, M; Chandrasena, G; Chang, SY; Chen, S; Cheng, L; Cheng, PT; Devasthale, PV; Doweyko, A; Farrelly, D; Golla, R; Grover, G; Hariharan, N; Harrity, T; Humphreys, WG; Jeon, Y; Ma, Z; Moore, L; Qu, F; Ren, J; Ryono, DE; Sasseville, VG; Seethala, R; Selan, F; Shao, C; Sleph, P; Sun, W; Tieman, A; Wang, W; Wetterau, JR; Zhang, H	1
Barlocco, D	1
Erlich, R	1
Buse, JB; Davidson, JA; Frederich, R; Lin, KC; Montoro, R; Rubin, CJ; Shockey, G; Viraswami-Appanna, K	1
Nissen, SE; Topol, EJ; Wolski, K	1
Brophy, JM	1
Aranibar, N; Bonacorsi, S; Cheng, PT; Hanson, R; Huang, Y; Humphreys, WG; Swaminathan, A; Wu, S; Zhang, D; Zhang, H; Zhu, M	1
Kordella, T	1
Doux, JD; Lee, PY; Yun, AJ	1
Cox, SL	1
Biller, S; Cap, M; Chen, S; Cheng, PT; Chu, C; Devasthale, P; Farrelly, D; Fenderson, W; Gregg, R; Gu, L; Hariharan, N; Harrity, T; Jeon, Y; Kunselman, L; Mookhtiar, KA; Ponticiello, R; Qu, F; Ren, J; Ryono, D; Seethala, R; Shao, C; Tieman, A; Wang, W; Wetterau, J; Yang, WP; Zhang, H; Zhou, M	1
Aurang, C; Cheng, PT; Everett, DW; Humphreys, WG; Mosqueda-Garcia, R; Swaminathan, A; Wang, L; Wu, S; Xue, Y; Zhang, D	1
Liu, J; Pursley, J; Unger, S; Xue, YJ	1
Cheng, PT; Everett, DW; Humphreys, WG; Li, W; Wang, L; Zhang, D; Zhang, H	1
Lebovitz, H	1
Srinivas, N; Yao, M	1
Liu, J; Unger, S; Xue, YJ	1
Finkelstein, JB	1
Heinzl, S	1
Liebson, PR	1
Belder, R; DeFronzo, RA; Fiedorek, FT; Gross, J; Kendall, DM; Ledeine, JM; Mohideen, P; Norwood, P; O'Mahony, M; Roberts, A; Rubin, CJ; Sall, K; Sloan, G	1
Beckey, C; Parra, D; Thomas, T	1
Najman, DM	1
Doggrell, SA	1
Ceska, R; Stulc, T	1
Fiévet, C; Fruchart, JC; Staels, B	1
Bonacorsi, S; Chandrasena, G; Cheng, PT; Hariharan, N; Hosagrahara, V; Humphreys, WG; Li, W; Mitroka, J; Raghavan, N; Shyu, WC; Wang, L; Yao, M; Yeola, S; Zhang, D; Zhang, H; Zhang, L; Zhu, M	1
Chandrasena, G; Davis, CD; Humphreys, WG; Ma, L; Wang, L; Zhang, D; Zhang, H; Zhu, M	1
Srinivas, N; Swaminathan, A; Yao, M	1
Arnold, LL; Cano, M; Cohen, SM; Dominick, MA; Mitroka, J; Sanderson, TP; Schilling, BE; Van Vleet, TR; Waites, CR; White, MR	1
Chandrasena, G; Chang, SY; Cheng, PT; Hariharan, N; Hosagrahara, VP; Humphreys, WG; Koplowitz, B	1
Arnold, LE; Cano, M; Cohen, SM; Dominick, MA; Moehlenkamp, JD; Sanderson, TP; Schilling, BE; Tannehill-Gregg, S; Van Vleet, T; Waites, CR; White, MR	1
Bansal, VS; Bora, RS; Gupta, A; Khanna, V; Khattar, SK; Mittra, S; Priyadarsiny, P; Roy, S; Saini, KS; Sangle, G; Sattigeri, J; Sharma, L; Sharma, S; Tandon, R	1
Belder, R; Chen, S; Cheng, PT; Devasthale, P; Egan, D; Farrelly, D; French, M; Gu, L; Hariharan, N; Harrity, T; Janovitz, E; Kunselman, L; Peters, A; Ponticiello, R; Staal, A; Swartz, J; Taylor, S; Tozzo, E; Welzel, G; Whaley, J; Zebo, R	1
Arnold, LL; Cohen, SM; Dominick, MA; Minnema, D; Sanderson, TP; Schilling, BE; Tannehill-Gregg, SH; Ulland, B; Voelker, R; Waites, CR	1
Amat, M; Bosch, J; Escolano, C; Lozano, O; Molins, E	1
Kim, JK; Kim, MK; Kim, NJ; Koo, BW; Lee, KO; Li, F; Lim, JI; Min, KH; Park, HJ; Suh, YG; Yoo, JK	1
Dominick, MA; Sanderson, TP; Schilling, BE; Waites, CR	1
Miller, JW; Ohmer, J; Sasich, LD	1
Akinsanya, JB; Raghavan, N; Xue, YJ; Zhang, D	1
Moseley, RH	1
Fiedorek, FT; Ledeine, JM; Rubin, CJ	1
Achanzar, W; Cheng, P; Cosma, G; Delmonte, T; Dracopoli, NC; Geese, WJ; Hariharan, N; Hui, L; Krishnan, B; Ordway, N; Ranade, K; Rubin, C; Tomlinson, L	1
Goel, A; Jain, M; Jamili, J; Makadia, P; Patel, M; Patel, P; Patil, P; Pingali, H; Sairam, KV; Shah, S; Zaware, P	1
Cheng, PT; Zhang, D; Zhang, H	1
Wang, L; Zhang, D; Zhao, W; Zhu, M	1
Charbonnel, B	1
Beaudet, I; Coeffard, V; Evain, M; Le Grognec, E; Quintard, JP	1
Sasich, LD; Sukkari, SR; Tuttle, DA	1
An, Y; Blanar, MA; Bolton, SA; Cap, M; Chang, C; Chen, BC; Chen, S; Chen, SY; Cheng, PT; Devasthale, PV; Grimm, D; Harrity, T; Hernández, AS; Hosagrahara, V; Kadiyala, P; Kennedy, LJ; Krystek, SR; Kunselman, LK; Lai, Z; Li, J; Li, YX; Lim, NK; Locke, KT; Meyers, DS; Miao, B; Monshizadegan, H; Muckelbauer, JK; Mukherjee, R; O'Malley, KM; Ryono, DE; Search, D; Shi, Y; Smirk, RA; Srivastava, RA; Tao, S; Tino, JA; Wang, W; Wang, Y; Wu, S; Xu, C; Ye, XY; Zahler, R; Zhang, H; Zhang, L; Zhang, R	1
De Pril, V; Fiedorek, FT; Rubin, CJ	1
Fiedorek, FT; Rubin, CJ; Viraswami-Appanna, K	1
Ciufolini, MA; Coqueron, PY; Vors, JP; Zhang, J	1
Chen, S; Cheng, PT; Humphreys, WG; Li, W; Obermeier, M; Raghavan, N; Ramanathan, R; Tao, S; Wang, L; Xue, Y; Yang, Z; Zhang, D; Zhang, H	1
Jirgensons, A; Klimovica, K; Maleckis, A	1
Bonacorsi, S; Chen, S; Cheng, PT; Humphreys, WG; Munsick, C; Wang, L; Zhang, D	1
Ji, G; Li, Z; Neugebauer, V	1
Claude, N; Guillouzo, A; Renaud, MP; Rogue, A; Spire, C	1
Casolaro, A; Cersosimo, E; DeFronzo, RA; Fernandez, M; Ferrannini, E; Gastaldelli, A; Hardies, J; Musi, N; Petz, R; Tantiwong, P; Triplitt, C	1
Amacher, DE; Boucher, GG; Francone, O; Kerlin, RL; Morton, D; Pettersen, JC; Pruimboom-Brees, IM; Will, Y	1
Farkouh, M; Plutzky, J; Rosenson, RS; Wright, RS	1
Asmawi, MZ; Aulaskari, PH; Kolmonen, A; Leppänen, T; Lindholm, M; Moilanen, E; Paukkeri, EL; Yam, MF	1
Anthérieu, S; Claude, N; de la Moureyre-Spire, C; Guillouzo, A; Rogue, A; Umbdenstock, T; Vluggens, A; Weaver, RJ	1
Brito, JP; Gionfriddo, MR; Leppin, AL; Montori, VM; Morey-Vargas, OL; Murad, MH	1
Hämäläinen, M; Isotalo, T; Kellomäki, M; Kotsar, A; Laurila, M; Salenius, JP; Suominen, V; Tammela, TL; Uurto, I	1
Cersosimo, E; Coletta, DK; DeFronzo, RA; Fernandez, M; Gastaldelli, A; Musi, N	1
Amoroso, R; Maccallini, C; Mollica, A	1
D'Aniello, E; Damaj, MI; Di Marzo, V; Donvito, G; Giordano, C; Guida, F; Ignatowska-Jankowska, BM; Jackson, A; Lichtman, AH; Maione, S; Mechoulam, R; Muldoon, P; Mustafa, MA; Parker, L; Petrie, GN; Piscitelli, F; Sim-Selley, L; Smoum, R; Vitale, RM	1
Benfodda, Z; Benimélis, D; Meffre, P; Reginato, G	1
Califf, RM; Demets, D; George, JT; Gerstein, HC; Granger, C; Green, JB; Hobbs, T; Holman, RR; Lawson, FC; Leiter, LA; McGuire, DK; McMurray, J; Pagidipati, NJ; Pfeffer, MA; Reusch, J; Riesmeyer, JS; Roe, MT; Rosenberg, Y; Sharma, A; Temple, R; Wiviott, S	1
Li, Y; Xie, Z; Yang, X; Zhang, Y; Zhu, Y	1
Drosatos, K; Kalliora, C	1

Reviews

12 review(s) available for oxazoles and glycine

Article	Year
Acivicin. An antitumor antibiotic. Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Glycine; Humans; Isoxazoles; Neoplasms; Neoplasms, Experimental; Oxazoles	1981
Muraglitazar (Bristol-Myers Squibb/Merck). Current opinion in investigational drugs (London, England : 2000), 2005, Volume: 6, Issue:4 Topics: Animals; Drug Industry; Glycine; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma	2005
Muraglitazar: an agent for the treatment of type 2 diabetes and associated dyslipidemia. Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:9 Topics: Adult; Aged; Animals; Area Under Curve; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Dyslipidemias; Female; Glycated Hemoglobin; Glycine; Half-Life; Humans; Hypoglycemic Agents; Male; Oxazoles; Peroxisome Proliferator-Activated Receptors; Tissue Distribution	2005
Diabetes: assessing the pipeline. Atherosclerosis. Supplements, 2006, Volume: 7, Issue:1 Topics: Adamantane; Alkanesulfonates; Amyloid; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Exenatide; Glycine; Humans; Hypoglycemic Agents; Indoles; Islet Amyloid Polypeptide; Maleimides; Nitriles; Oxazoles; Peptides; Phenylpropionates; Piperidines; PPAR alpha; PPAR gamma; Protein Kinase C; Pyrazoles; Pyrrolidines; Receptor, Cannabinoid, CB1; Receptors, Glucagon; Rimonabant; Venoms; Vildagliptin	2006
[Dipeptidylpeptidase IV inhibitors and dual action PPAR-agonists]. Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:3 Topics: Adamantane; Adenosine Deaminase Inhibitors; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glycine; Glycoproteins; Humans; Hypoglycemic Agents; Nitriles; Oxazoles; Peroxisome Proliferator-Activated Receptors; Protease Inhibitors; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin	2006
Muraglitazar and the FDA: what constitutes drug safety? Preventive cardiology, 2006,Spring, Volume: 9, Issue:2 Topics: Animals; Blood Glucose; Databases, Factual; Diabetes Mellitus, Type 2; Drug Approval; Glycine; Humans; Oxazoles; Peroxisome Proliferator-Activated Receptors; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration	2006
PPARalpha and PPARgamma dual agonists for the treatment of type 2 diabetes and the metabolic syndrome. Current opinion in pharmacology, 2006, Volume: 6, Issue:6 Topics: Alkanesulfonates; Animals; Diabetes Mellitus, Type 2; Glycine; Humans; Metabolic Syndrome; Models, Biological; Oxazoles; Phenylpropionates; PPAR alpha; PPAR gamma	2006
Modulating peroxisome proliferator-activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects. American heart journal, 2012, Volume: 164, Issue:5 Topics: Alkanesulfonates; Diabetic Angiopathies; Glycine; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Oxazines; Oxazoles; Phenylpropionates; Phosphorylation; PPAR alpha; PPAR delta; PPAR gamma; Thiazolidinediones; Thiophenes; United States; United States Food and Drug Administration	2012
Systematic reviews to ascertain the safety of diabetes medications. Current diabetes reports, 2014, Volume: 14, Issue:4 Topics: Acidosis, Lactic; Blood Glucose; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Female; Fractures, Bone; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Male; Meta-Analysis as Topic; Metformin; Oxazoles; Pancreatic Neoplasms; Risk Assessment; Rosiglitazone; Thiazolidinediones; Urinary Bladder Neoplasms	2014
The Positive Regulation of eNOS Signaling by PPAR Agonists in Cardiovascular Diseases. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2017, Volume: 17, Issue:4 Topics: Animals; Cardiovascular Diseases; Glycine; Humans; Nitric Oxide Synthase Type III; Oxazoles; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Signal Transduction; Thiazolidinediones	2017
Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon. Amino acids, 2018, Volume: 50, Issue:10 Topics: Biphenyl Compounds; Catalysis; Glycine; Oxazoles; Stereoisomerism	2018
The Glitazars Paradox: Cardiotoxicity of the Metabolically Beneficial Dual PPARα and PPARγ Activation. Journal of cardiovascular pharmacology, 2020, Volume: 76, Issue:5 Topics: Alkanesulfonates; Animals; Cardiotoxicity; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Energy Metabolism; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Phenylpropionates; PPAR alpha; PPAR gamma; Risk Assessment; Risk Factors; Signal Transduction; Thiophenes	2020

Trials

11 trial(s) available for oxazoles and glycine

Article	Year
Muraglitazar, a dual (alpha/gamma) PPAR activator: a randomized, double-blind, placebo-controlled, 24-week monotherapy trial in adult patients with type 2 diabetes. Clinical therapeutics, 2005, Volume: 27, Issue:8 Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Oxazoles; Peroxisome Proliferator-Activated Receptors	2005
Structural elucidation of human oxidative metabolites of muraglitazar: use of microbial bioreactors in the biosynthesis of metabolite standards. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:2 Topics: Bioreactors; Biotransformation; Cunninghamella; Feces; Glycine; Humans; Oxazoles; Oxidation-Reduction; PPAR alpha; PPAR gamma; Saccharopolyspora	2006
Improvement of glycemic control, triglycerides, and HDL cholesterol levels with muraglitazar, a dual (alpha/gamma) peroxisome proliferator-activated receptor activator, in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A Diabetes care, 2006, Volume: 29, Issue:5 Topics: Adult; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycine; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones; Triglycerides	2006
Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:1 Topics: Animals; Bile; Dogs; Feces; Glycine; Hepatocytes; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Oxazoles; PPAR alpha; PPAR gamma; Protein Binding; Rats; Rats, Sprague-Dawley	2007
Improvement of glycaemic and lipid profiles with muraglitazar plus metformin in patients with type 2 diabetes: an active-control trial with glimepiride. Diabetes & vascular disease research, 2008, Volume: 5, Issue:3 Topics: Administration, Oral; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Metformin; Middle Aged; Oxazoles; Sulfonylurea Compounds; Time Factors; Treatment Outcome	2008
Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists. Pharmacogenetics and genomics, 2008, Volume: 18, Issue:10 Topics: Animals; Diabetes Mellitus, Type 2; Edema; Endothelin-1; Female; Gene Expression Regulation; Glycine; Humans; Macaca fascicularis; Male; Oxazoles; Pharmacogenetics; Polymorphism, Single Nucleotide; PPAR gamma; Regression Analysis; Renin	2008
Coadministration of muraglitazar plus glyburide: improvement of glycaemic and lipid profiles in patients with type 2 diabetes. Diabetes & vascular disease research, 2009, Volume: 6, Issue:2 Topics: Administration, Oral; Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Oxazoles; PPAR alpha; PPAR gamma; Time Factors; Treatment Outcome	2009
Efficacy and safety of muraglitazar: a double-blind, 24-week, dose-ranging study in patients with type 2 diabetes. Diabetes & vascular disease research, 2009, Volume: 6, Issue:3 Topics: Biomarkers; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Female; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Insulin; Lipids; Male; Middle Aged; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones; Time Factors; Treatment Outcome; Weight Gain	2009
Metabolism and disposition of 14C-labeled peliglitazar in humans. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Bile; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Feces; Glycine; Humans; Male; Mass Spectrometry; Middle Aged; Molecular Structure; Oxazoles; Peroxisome Proliferator-Activated Receptors; Tissue Distribution; Young Adult	2011
Metabolic effects of muraglitazar in type 2 diabetic subjects. Diabetes, obesity & metabolism, 2011, Volume: 13, Issue:10 Topics: Body Mass Index; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Glycine; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Intra-Abdominal Fat; Male; Middle Aged; Oxazoles; Peroxisome Proliferator-Activated Receptors	2011
The effect of muraglitazar on adiponectin signalling, mitochondrial function and fat oxidation genes in human skeletal muscle in vivo. Diabetic medicine : a journal of the British Diabetic Association, 2015, Volume: 32, Issue:5 Topics: Adiponectin; AMP-Activated Protein Kinases; Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glycine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Oxazoles; Oxidation-Reduction; PPAR alpha; PPAR gamma; Signal Transduction; Triglycerides	2015

Other Studies

103 other study(ies) available for oxazoles and glycine

Article	Year
Distribution and effect of the weak acids 5,5-dimethyl-2,4-oxazolidinedione (DMO) and 2,4-dinitrophenol (DNP) in membrane vesicles of Micrococcus denitrificans. Archives of biochemistry and biophysics, 1976, Volume: 176, Issue:1 Topics: Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Dimethadione; Dinitrophenols; Glycine; Hydrogen-Ion Concentration; Mathematics; Oxazoles; Oxygen Consumption; Paracoccus denitrificans	1976
Biochemical and pharmacological effects of the fermentation-derived antitumor agent, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). Cancer research, 1979, Volume: 39, Issue:3 Topics: 3-Deazauridine; Animals; Antibiotics, Antineoplastic; Drug Resistance; Female; Glycine; Isoxazoles; Lethal Dose 50; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Nucleotides; Oxazoles; Sex Factors	1979
Therapy for mouse tumors and human tumor xenografts with the antitumor antibiotic AT-125. Cancer treatment reports, 1979, Volume: 63, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Glycine; Humans; Isoxazoles; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Oxazoles; Transplantation, Heterologous	1979
Enhanced effect of an L-glutamine antagonist, L-(alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, by Acinetobacter L-glutaminase-L-asparaginase. Cancer treatment reports, 1979, Volume: 63, Issue:6 Topics: Acinetobacter; Amino Acids; Animals; Asparaginase; Carcinoma, Ehrlich Tumor; Drug Synergism; Drug Therapy, Combination; Female; Glutaminase; Glutamine; Glycine; Isoxazoles; Lethal Dose 50; Leukemia L1210; Male; Mice; Oxazoles	1979
Studies of the biochemical pharmacology of the fermentation-derived antitumor agent, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). Advances in enzyme regulation, 1978, Volume: 17 Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line; Cell Survival; Female; Glutamine; Glycine; Isoxazoles; Leukemia L1210; Leukemia P388; Macromolecular Substances; Male; Mice; Oxazoles; Sex Factors; Thymidine; Uridine; Valine	1978
The isolation, structure, and absolute configuration of U-43,795, a new antitumor agent. The Journal of antibiotics, 1975, Volume: 28, Issue:1 Topics: Amino Acids; Antimetabolites, Antineoplastic; Chemical Phenomena; Chemistry; Glycine; Isoxazoles; Molecular Conformation; Molecular Weight; Oxazoles; Streptomyces	1975
A novel method for the gas chromatographic determination of phenylalanine in serum. Biochemical medicine, 1975, Volume: 12, Issue:2 Topics: Chromatography, Gas; Glycine; Humans; Methods; Oxazoles; Phenylalanine; Phenylketonurias	1975
Improved methods for production, isolation, and assay of two new chlorisoxazoline amino acid antitumor antimetabolites: U-42, 126 and U43, 795. Antimicrobial agents and chemotherapy, 1975, Volume: 7, Issue:6 Topics: Antibiotics, Antineoplastic; Antimetabolites; Glycine; Isoxazoles; Methods; Oxazoles	1975
The expression of excitatory amino acid binding sites during neuritogenesis in the developing rat cerebellum. Brain research. Developmental brain research, 1990, Jul-01, Volume: 54, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebellum; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Oxazoles; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
Evaluation and synthesis of aminohydroxyisoxazoles and pyrazoles as potential glycine agonists. Journal of medicinal chemistry, 1989, Volume: 32, Issue:9 Topics: Animals; Brain; Chemical Phenomena; Chemistry; Detergents; Glycine; Isoxazoles; Models, Molecular; Oxazoles; Pyrazoles; Quaternary Ammonium Compounds; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Structure-Activity Relationship	1989
Synthesis and biological activity of a GABAA agonist which has no effect on benzodiazepine binding and of structurally related glycine antagonists. Drug design and delivery, 1987, Volume: 1, Issue:4 Topics: Animals; Bicuculline; Brain Chemistry; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Isoxazoles; Oxazoles; Piperidines; Pyrrolidines; Rats; Receptors, GABA-A; Synaptic Membranes	1987
Amplification by glycine of the anticonvulsant effect of THPO, a GABA uptake inhibitor. General pharmacology, 1985, Volume: 16, Issue:5 Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Male; Mice; Neurotransmitter Uptake Inhibitors; Oxazoles; Pentylenetetrazole; Seizures	1985
Glycine antagonists. Synthesis, structure, and biological effects of some bicyclic 5-isoxazolol zwitterions. Journal of medicinal chemistry, 1986, Volume: 29, Issue:2 Topics: Animals; Glycine; In Vitro Techniques; Isoxazoles; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxazoles; Rats; Receptors, GABA-A; Spectrophotometry, Infrared; Structure-Activity Relationship	1986
Glycine antagonists structurally related to 4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridin-3-ol inhibit binding of [3H]strychnine to rat brain membranes. Journal of neurochemistry, 1986, Volume: 47, Issue:3 Topics: Animals; Anions; Binding, Competitive; Cell Membrane; Chlorides; Choline; GABA Antagonists; Glycine; Isoxazoles; Male; Medulla Oblongata; Oxazoles; Pons; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Sodium Chloride; Strychnine	1986
Amplification by glycine of the effect of the GABA transport inhibitor THPO on synaptosomal GABA level. Neurochemical research, 1988, Volume: 13, Issue:10 Topics: Amino Acids; Animals; Brain; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Male; Mice; Oxazoles; Synaptosomes	1988
Reaction of hexafluoroacetone with certain simple peptides and related compounds. The Journal of organic chemistry, 1973, Jan-12, Volume: 38, Issue:1 Topics: Acetone; Alanine; Chemical Phenomena; Chemistry; Fluorine; Glycine; Imidazoles; Oxazoles; Peptides	1973
U-42, 126, a new antimetabolite antibiotic: production, biological activity, and taxonomy of the producing microorganism. Antimicrobial agents and chemotherapy, 1973, Volume: 3, Issue:3 Topics: Antibiotics, Antineoplastic; Antifungal Agents; Antimetabolites; Bacteria; Chromatography, Paper; Glycine; Microbial Sensitivity Tests; Oxazoles; Streptomyces	1973
Modification of carboxyl groups in bovine carboxypeptidase A. I. Inactivation of the enzyme by N-ethyl-5-phenylisoxazolium-3'-sulfonate (Woodward's reagent K). Biochemistry, 1971, Aug-17, Volume: 10, Issue:17 Topics: Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Cinnamates; Dipeptides; Ethylamines; Glycine; Hydrogen-Ion Concentration; Indoleacetic Acids; Kinetics; Lactates; Mathematics; Methoxamine; Models, Structural; Oxazoles; Phenylacetates; Phenylbutyrates; Propionates; Spectrophotometry; Sulfonic Acids; Tyrosine; Ultraviolet Rays	1971
Stimulation of amino acid metabolism and gluconeogenesis from amino acids in the liver of fasting rats treated with antilipolytic agents. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1970, Volume: 351, Issue:3 Topics: Alanine; Animals; Carbon Isotopes; Fasting; Gluconeogenesis; Glycine; Hypolipidemic Agents; In Vitro Techniques; Lipid Mobilization; Liver; Liver Glycogen; Oxazoles; Perfusion; Rats; Stimulation, Chemical	1970
[Cyclization by the intermediates of phenylthio- and phenoxy carbamoyl. Formation of azasuccinic anhydrides and their polycondensation products. Intervention of the carbamoyl pyridinium cation]. Helvetica chimica acta, 1970, Volume: 53, Issue:4 Topics: Alanine; Carbamates; Glycine; Leucine; Muramidase; Oxazoles; Peptides; Pyridines; Spectrum Analysis	1970
On the mechanism of hydrolysis of N-acylamino acid nitrophenyl esters. Biochemical and biophysical research communications, 1966, Jun-13, Volume: 23, Issue:5 Topics: Chemical Phenomena; Chemistry; Glycine; Hippurates; Kinetics; Nitrophenols; Oxazoles; Spectrophotometry	1966
The interaction of azlactone with aldolase. Acta biochimica Polonica, 1967, Volume: 14, Issue:2 Topics: Animals; Buffers; Fructose-Bisphosphate Aldolase; Glycine; Hydrogen-Ion Concentration; Kinetics; Lysine; Muscles; Oxazoles; Phosphates; Proline; Rabbits; Spectrophotometry; Temperature; Thioglycolates	1967
The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501). Research communications in chemical pathology and pharmacology, 1980, Volume: 27, Issue:1 Topics: Antibiotics, Antineoplastic; Cells, Cultured; gamma-Glutamyltransferase; Glycine; Half-Life; Humans; Isoxazoles; Oxazoles; Pancreatic Neoplasms; Time Factors	1980
The inhibition of gamma-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(alpha S, 5S)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501). Biochemical and biophysical research communications, 1980, Jun-30, Volume: 94, Issue:4 Topics: Animals; Cells, Cultured; gamma-Glutamyltransferase; Glutathione; Glycine; Isoxazoles; Kidney; Kinetics; Male; Oxazoles; Rats	1980
The effect of the glutamine analog, AT-125, on the cell cycle of MCF-7 and BT-20 human breast carcinoma cells using DNA flow cytometry. Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:2 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cytological Techniques; DNA, Neoplasm; gamma-Glutamyltransferase; Glycine; Humans; Isoxazoles; Oxazoles	1980
Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase. Chemico-biological interactions, 1981, Volume: 33, Issue:2-3 Topics: Anilides; Animals; Cattle; gamma-Glutamyltransferase; Glutamates; Glutamine; Glycine; In Vitro Techniques; Isoxazoles; Kidney; Kinetics; Oxazoles	1981
Affinity labeling of gamma-glutamyl transpeptidase by glutamine antagonists. Effects of the gamma-glutamyl transferase and proteinase activities. FEBS letters, 1980, Dec-29, Volume: 122, Issue:2 Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; gamma-Glutamyltransferase; Glycine; Isoxazoles; Kidney; Macromolecular Substances; Oxazoles; Rats; Structure-Activity Relationship	1980
Interaction of the antitumor drug, L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) with renal brush border membranes. Specific labeling of gamma-glutamyl transpeptidase. FEBS letters, 1980, Dec-29, Volume: 122, Issue:2 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; gamma-Glutamyltransferase; Glycine; Isoxazoles; Kidney; Male; Microvilli; Molecular Weight; Oxazoles; Rats	1980
Differential effect of AT-125 on rat renal glutaminase activities. FEBS letters, 1981, Oct-12, Volume: 133, Issue:1 Topics: Ammonia; Animals; gamma-Glutamyltransferase; Glutaminase; Glutamine; Glycine; Isoxazoles; Kidney; Kinetics; Male; Oxazoles; Phosphates; Rats	1981
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine. Journal of neurochemistry, 1982, Volume: 39, Issue:5 Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship	1982
Depolarizing responses to glycine, beta-alanine and muscimol in isolated optic nerve and cuneate nucleus. British journal of pharmacology, 1983, Volume: 79, Issue:3 Topics: Alanine; Animals; beta-Alanine; Bicuculline; Dose-Response Relationship, Drug; Glycine; Male; Medulla Oblongata; Muscimol; Optic Nerve; Oxazoles; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine; Time Factors	1983
Autoradiographic studies of [3H]-glycine, [3H]-GABA, and [3H]-muscimol uptake in the mudpuppy retina. Experimental eye research, 1984, Volume: 39, Issue:1 Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Microscopy, Electron; Muscimol; Necturus; Oxazoles; Retina; Tritium	1984
Synergistic anticonvulsant effects of a GABA agonist and glycine. General pharmacology, 1984, Volume: 15, Issue:4 Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Male; Mice; Muscimol; Oxazoles; Seizures	1984
Mechanism of inactivation of glutamine amidotransferases by the antitumor drug L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). The Journal of biological chemistry, 1980, Jul-25, Volume: 255, Issue:14 Topics: Anthranilate Synthase; Binding, Competitive; Glutamate Synthase; Glutamine; Glycine; Isoxazoles; Kinetics; Nitrogenous Group Transferases; Oxazoles; Serratia marcescens; Transferases	1980
Biochemical pharmacology of acivicin in rat hepatoma cells. Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21 Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Survival; Cytidine; Deoxycytidine; Deoxyribonucleotides; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Guanosine; Isoxazoles; Ligases; Liver; Liver Neoplasms, Experimental; Oxazoles; Rats; Ribonucleotides	1982
Sex- and age-related mouse toxicity and disposition of the amino acid antitumor agent, acivicin. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 216, Issue:3 Topics: Age Factors; Animals; Antineoplastic Agents; Female; Glycine; Half-Life; Isoxazoles; Kinetics; Male; Metabolic Clearance Rate; Mice; Oxazoles; Sex Factors; Testosterone; Tissue Distribution	1981
Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase. Cancer research, 1981, Volume: 41, Issue:4 Topics: Amidohydrolases; Animals; Asparagine; Azo Compounds; Cell Line; Diazooxonorleucine; DNA; Glutamine; Glycine; Isoxazoles; Kinetics; Leukemia L1210; Mice; Oxazoles; Temperature	1981
Synergistic effects with inhibitors of de novo pyrimidine synthesis, acivicin, and N-(phosphonacetyl)-L-aspartic acid. Cancer research, 1981, Volume: 41, Issue:9 Pt 1 Topics: Animals; Aspartic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Deoxyribonucleosides; Drug Synergism; Glycine; Isoxazoles; Leukemia L1210; Mice; Organophosphorus Compounds; Orotic Acid; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Ribonucleosides	1981
Derivatization and purification of acivicin (AT-125, U-42,126). The Journal of antibiotics, 1981, Volume: 34, Issue:4 Topics: Antibiotics, Antineoplastic; Antimetabolites; Glycine; Isoxazoles; Oxazoles	1981
Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 313, Issue:3 Topics: Anesthesia; Animals; Dopamine; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Injections, Intraventricular; Male; Muscimol; Oxazoles; Parasympathetic Nervous System; Rats; Serotonin; Sympathetic Nervous System	1980
Therapeutic effects of acivicin and N-(phosphonacetyl)-L-aspartic acid in a biochemically designed trial against a N-(phosphonacetyl)-L-aspartic acid-resistant variant of the Lewis lung carcinoma. Cancer research, 1981, Volume: 41, Issue:3 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma; Drug Therapy, Combination; Glycine; Isoxazoles; Ligases; Lung Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Rats	1981
Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature, 1994, May-19, Volume: 369, Issue:6477 Topics: Cells, Cultured; Ethers, Cyclic; Glycine; Hippocampus; Marine Toxins; Membrane Potentials; N-Methylaspartate; Neurons; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Receptors, N-Methyl-D-Aspartate	1994
Down-regulation of murine contact sensitivity by hapten-amino acid derivatives. International archives of allergy and immunology, 1993, Volume: 102, Issue:1 Topics: Amino Acids; Animals; Dermatitis, Allergic Contact; Desensitization, Immunologic; Down-Regulation; Glycine; Haptens; Lymph Nodes; Lymphocyte Activation; Lysine; Male; Mice; Mice, Inbred BALB C; Oxazoles; Oxazolone; Receptors, Antigen, T-Cell; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory; Trinitrobenzenes	1993
Genotoxicity and oxidative stress induced by pesticide exposure in bovine lymphocyte cultures in vitro. Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2 Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Chromosome Aberrations; Glucosephosphate Dehydrogenase; Glycine; Glyphosate; In Vitro Techniques; Lymphocytes; Mitotic Index; Mutagenicity Tests; Mutagens; Oxazoles; Oxidation-Reduction; Oxidative Stress; Pesticides; Sister Chromatid Exchange; Urea	1998
Enhancement of glycine receptor function by ethanol: role of phosphorylation. British journal of pharmacology, 1998, Volume: 125, Issue:2 Topics: Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Female; Glycine; Glycine Agents; Halothane; Humans; Indoles; Maleimides; Marine Toxins; Oocytes; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Propofol; Protein Kinase C; Receptors, Glycine; Staurosporine; Strychnine; Xenopus laevis	1998
(S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: ideal Michael acceptors to afford a virtually complete control of simple and face diastereoselectivity in addition reactions with glycine derivatives. Organic letters, 2000, Mar-23, Volume: 2, Issue:6 Topics: Glycine; Indicators and Reagents; Molecular Structure; Oxazoles; Stereoisomerism	2000
Oxygen uptake, acidification of medium and nitrate uptake induced by blue light in nitrate-starved Chlorella cells. Plant & cell physiology, 2000, Volume: 41, Issue:4 Topics: Biological Transport; Chlorella; Color; Glycine; Light; Marine Toxins; Nitrates; Okadaic Acid; Oxazoles; Oxygen; Phosphoprotein Phosphatases	2000
Fluorescence sensing of ammonium and organoammonium ions with tripodal oxazoline receptors. Organic letters, 2003, May-01, Volume: 5, Issue:9 Topics: Cations; Electron Transport; Ethanolamines; Fluorescent Dyes; Glycine; Oxazoles; Phenethylamines; Photochemistry; Propanolamines; Quantum Theory; Quaternary Ammonium Compounds; Sensitivity and Specificity; Spectrometry, Fluorescence; Stereoisomerism	2003
Photolysis of postsynaptic caged Ca2+ can potentiate and depress mossy fiber synaptic responses in rat hippocampal CA3 pyramidal neurons. Journal of neurophysiology, 2004, Volume: 91, Issue:4 Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Benzothiazoles; Calcium; Coumarins; Cyclopropanes; Cyclosporine; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Marine Toxins; Mossy Fibers, Hippocampal; Oxazoles; Patch-Clamp Techniques; Photolysis; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission	2004
Role of protein phosphatase 2A in mGluR5-regulated MEK/ERK phosphorylation in neurons. The Journal of biological chemistry, 2005, Apr-01, Volume: 280, Issue:13 Topics: Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glycine; Immunoprecipitation; MAP Kinase Kinase 1; Marine Toxins; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Okadaic Acid; Oxazoles; Peptides; Phenylacetates; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction; Threonine; Time Factors; Up-Regulation	2005
Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious glucose and Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6 Topics: Adipocytes; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Fatty Acids; Glycine; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Mice; Mice, Obese; Oxazoles; PPAR alpha; PPAR gamma; Transcriptional Activation; Triglycerides	2005
Molecule of the month. Muraglitazar. Drug news & perspectives, 2005, Volume: 18, Issue:4 Topics: Diabetes Mellitus, Type 2; Glycine; Humans; Oxazoles; PPAR alpha; PPAR gamma	2005
American Diabetes Association - 65th Scientific Sessions. PPAR agents. IDrugs : the investigational drugs journal, 2005, Volume: 8, Issue:8 Topics: Alkanesulfonates; Animals; Blood Glucose; Diabetes Mellitus; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Peroxisome Proliferator-Activated Receptors; Phenylpropionates	2005
Meeting highlights. 65th annual scientific sessions of the American Diabetes Association, San Diego. Dual PPAR agonist improves glycemic control, lipids in type 2 diabetes. Geriatrics, 2005, Volume: 60, Issue:8 Topics: Diabetes Mellitus, Type 2; Glycine; Humans; Hypoglycemic Agents; Metabolic Syndrome; Oxazoles; Pioglitazone; Thiazolidinediones; United States	2005
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus. JAMA, 2005, Nov-23, Volume: 294, Issue:20 Topics: Cardiovascular Diseases; Clinical Trials as Topic; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Approval; Glycine; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Risk; Treatment Outcome; United States; United States Food and Drug Administration	2005
Selling safety--lessons from muraglitazar. JAMA, 2005, Nov-23, Volume: 294, Issue:20 Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Approval; Glycine; Humans; Hypoglycemic Agents; Oxazoles; PPAR alpha; PPAR gamma; Risk; United States; United States Food and Drug Administration	2005
One pill, two conditions. Diabetes forecast, 2005, Volume: 58, Issue:10 Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Glycine; Humans; Hypercholesterolemia; Oxazoles; United States	2005
Paradoxical inflammation revisited: muraglitazar and cardiovascular risk. Medical hypotheses, 2006, Volume: 66, Issue:4 Topics: Cardiovascular Diseases; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Risk	2006
Muraglitazar, a novel dual (alpha/gamma) peroxisome proliferator-activated receptor activator, improves diabetes and other metabolic abnormalities and preserves beta-cell function in db/db mice. Diabetes, 2006, Volume: 55, Issue:1 Topics: Adiponectin; Animals; Blood Glucose; Corticosterone; Diabetes Mellitus, Type 2; Diet; Female; Glycine; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Liver; Mice; Obesity; Oxazoles; Peroxisome Proliferator-Activated Receptors; Rosiglitazone; Thiazolidinediones	2006
Glucuronidation as a major metabolic clearance pathway of 14c-labeled muraglitazar in humans: metabolic profiles in subjects with or without bile collection. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:3 Topics: Bile; Carbon Radioisotopes; Glucuronides; Glycine; Humans; Male; Metabolic Clearance Rate; Metabolic Detoxication, Phase II; Molecular Structure; Oxazoles; PPAR alpha; PPAR gamma	2006
A 96-well single-pot protein precipitation, liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of muraglitazar, a novel diabetes drug, in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-02, Volume: 831, Issue:1-2 Topics: Animals; Chemical Precipitation; Chromatography, Liquid; Drug Stability; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2006
Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:5 Topics: Animals; Bile; Bile Ducts; Biotransformation; Chromatography, High Pressure Liquid; Feces; Glutathione; Glycine; Haplorhini; Humans; Hypoglycemic Agents; Male; Mass Spectrometry; Mice; Oxazoles; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Taurine	2006
Liquid chromatography/mass spectrometry for the quantitation of muraglitazar in monkey plasma. Biomedical chromatography : BMC, 2006, Volume: 20, Issue:10 Topics: Animals; Chromatography, High Pressure Liquid; Glycine; Haplorhini; Mass Spectrometry; Oxazoles; Reproducibility of Results	2006
A 96-well single-pot liquid-liquid extraction, hydrophilic interaction liquid chromatography-mass spectrometry method for the determination of muraglitazar in human plasma. Journal of pharmaceutical and biomedical analysis, 2006, Jun-07, Volume: 41, Issue:3 Topics: Chromatography, Liquid; Glycine; Humans; Oxazoles; PPAR alpha; PPAR gamma; Reference Standards; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2006
Drug safety system needs overhaul, experts say. Journal of the National Cancer Institute, 2006, Mar-15, Volume: 98, Issue:6 Topics: Cardiovascular Diseases; Conflict of Interest; Drug Approval; Drug-Related Side Effects and Adverse Reactions; Glycine; Heart; Humans; Journalism, Medical; Oxazoles; Peroxisome Proliferator-Activated Receptors; Publication Bias; United States; United States Food and Drug Administration	2006
Adverse events related to muraglitazar use in diabetes. JAMA, 2006, May-03, Volume: 295, Issue:17 Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Interactions; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones	2006
Adverse events related to muraglitazar use in diabetes. JAMA, 2006, May-03, Volume: 295, Issue:17 Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Interactions; Glycine; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Oxazoles; PPAR alpha; PPAR gamma	2006
Muraglitazar: beneficial or detrimental in the treatment of Type 2 diabetes? Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:9 Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glycine; Humans; Hypoglycemic Agents; Middle Aged; Oxazoles; Randomized Controlled Trials as Topic; Research Design; Weight Gain	2006
Is it safe to combine PPAR agonists? A lesson from muraglitazar. Medical hypotheses, 2006, Volume: 67, Issue:3 Topics: Cardiomyopathies; Drug Interactions; Glycine; Humans; Models, Biological; Oxazoles; PPAR alpha; PPAR gamma	2006
Involvement of multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes in the in vitro metabolism of muraglitazar. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:1 Topics: Antibodies, Monoclonal; Biotransformation; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glucuronosyltransferase; Glycine; Hepatocytes; Humans; Microsomes, Liver; Oxazoles; Oxidation-Reduction; PPAR alpha; PPAR gamma	2007
Assessment of dose proportionality of muraglitazar after repeated oral dosing in rats via a sparse sampling methodology. Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:1 Topics: Administration, Oral; Animals; Female; Glycine; Hypoglycemic Agents; Hypolipidemic Agents; Male; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Time Factors	2007
Subchronic urinary bladder effects of muraglitazar in male rats. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 96, Issue:1 Topics: Age Factors; Animals; Apoptosis; Calcium; Cell Proliferation; Citrates; Creatinine; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Glycine; Hyperplasia; Magnesium; Male; Oxalates; Oxazoles; Peroxisome Proliferators; Phosphorus; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Sex Factors; Time Factors; Urinary Bladder; Urine; Urothelium	2007
Pharmacokinetics of muraglitazar (BMS-298585), a dual peroxisome proliferator-activated receptors (PPAR) alpha and gamma activator, in mice, rats, dogs, and monkeys. Xenobiotica; the fate of foreign compounds in biological systems, 2006, Volume: 36, Issue:12 Topics: Administration, Oral; Animals; Biological Availability; Cross-Over Studies; Dogs; Glycine; Half-Life; Hepatocytes; In Vitro Techniques; Injections, Intravenous; Macaca fascicularis; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Species Specificity	2006
Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR alpha/gamma agonist: Evidence for urolithiasis as the inciting event in the mode of action. Toxicologic pathology, 2006, Volume: 34, Issue:7 Topics: Animals; Antimetabolites; Apoptosis; Area Under Curve; Bromodeoxyuridine; Calcium; Carcinogens; Cell Proliferation; Citrates; Electrolytes; Glycine; Hydrogen-Ion Concentration; Immunohistochemistry; Male; Microscopy, Electron, Scanning; Organ Size; Oxalates; Oxazoles; Phosphates; PPAR alpha; PPAR gamma; Proteinuria; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Urinary Bladder Neoplasms; Urolithiasis; Urothelium	2006
Increase in weight induced by muraglitazar, a dual PPARalpha/gamma agonist, in db/db mice: adipogenesis/or oedema? British journal of pharmacology, 2007, Volume: 150, Issue:4 Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Blood Glucose; Body Weight; Cell Differentiation; Edema; Epithelial Sodium Channels; Erythrocyte Count; Fatty Acids; Glycine; Hemoglobins; Kidney; Mice; Mice, Inbred Strains; Oxazoles; PPAR alpha; PPAR gamma; RNA, Messenger; Rosiglitazone; Sodium; Sodium-Potassium-Exchanging ATPase; Thiazolidinediones; Transcriptional Activation	2007
The dual peroxisome proliferator-activated receptor alpha/gamma activator muraglitazar prevents the natural progression of diabetes in db/db mice. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1 Topics: Animals; Body Weight; C-Peptide; Diabetes Mellitus, Experimental; Disease Progression; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glycine; Hypoglycemic Agents; Insulin; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxazoles; Pancreas; PPAR alpha; PPAR gamma; Triglycerides	2007
Rodent carcinogenicity profile of the antidiabetic dual PPAR alpha and gamma agonist muraglitazar. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:1 Topics: Animals; Carcinogenicity Tests; Carcinogens; Dose-Response Relationship, Drug; Female; Glycine; Hypoglycemic Agents; Male; Mice; Mice, Inbred ICR; Neoplasms; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Survival Analysis; Urinalysis	2007
Enantioselective synthesis of 3,3-disubstituted piperidine derivatives by enolate dialkylation of phenylglycinol-derived oxazolopiperidone lactams. The Journal of organic chemistry, 2007, Jun-08, Volume: 72, Issue:12 Topics: Alkylation; Ethanolamines; Glycine; Indole Alkaloids; Lactams; Oxazoles; Piperidines; Piperidones; Stereoisomerism	2007
Design, synthesis, and structure-activity relationship of carbamate-tethered aryl propanoic acids as novel PPARalpha/gamma dual agonists. Bioorganic & medicinal chemistry letters, 2007, Jul-01, Volume: 17, Issue:13 Topics: Carbamates; Chemistry, Pharmaceutical; Drug Design; Glycine; Models, Chemical; Models, Molecular; Molecular Structure; Oxazoles; PPAR alpha; PPAR gamma; Propionates; Rosiglitazone; Stereoisomerism; Structure-Activity Relationship; Thiazolidinediones; Transcriptional Activation	2007
Nonclinical safety evaluation of muraglitazar, a novel PPARalpha/gamma agonist. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1 Topics: Administration, Oral; Animals; Carcinogenicity Tests; Consumer Product Safety; Dogs; Female; Glycine; Hypoglycemic Agents; Lethal Dose 50; Macaca fascicularis; Male; Mice; Mice, Inbred ICR; Oxazoles; PPAR alpha; PPAR gamma; Promoter Regions, Genetic; Rabbits; Rats; Rats, Sprague-Dawley; Risk Assessment; Species Specificity; Toxicity Tests, Chronic; Transcriptional Activation	2007
A bumpy road to breakthroughs. The news: it's hard to beat today's cardiac treatments. Heart advisor, 2006, Volume: 9, Issue:2 Topics: Animals; Atherosclerosis; Coronary Thrombosis; Diabetes Mellitus, Type 2; Ethics, Clinical; Glycine; Heart Failure; Humans; Indoleacetic Acids; Myocardial Infarction; Oxazoles; Prostheses and Implants; Stroke; Treatment Failure; Ultrasonography	2006
Accessing FDA approval packages and briefing documents. The Annals of pharmacotherapy, 2007, Volume: 41, Issue:12 Topics: Documentation; Drug Approval; Glycine; Ketolides; Oxazoles; United States; United States Food and Drug Administration	2007
Optimization to eliminate the interference of migration isomers for measuring 1-O-beta-acyl glucuronide without extensive chromatographic separation. Rapid communications in mass spectrometry : RCM, 2008, Volume: 22, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Feasibility Studies; Glucuronides; Glycine; Haplorhini; Humans; Isomerism; Mice; Oxazoles; PPAR alpha; PPAR gamma; Rats	2008
Therapy for nonalcoholic fatty liver disease. Journal of clinical gastroenterology, 2008, Volume: 42, Issue:4 Topics: Animals; Antioxidants; Cholagogues and Choleretics; Disease Models, Animal; Fatty Liver; Glycine; Humans; Hypolipidemic Agents; Insulin Resistance; Liver; Mice; Oxazoles; Peroxisome Proliferator-Activated Receptors; Rats; Thiazolidinediones; Treatment Outcome; Ursodeoxycholic Acid; Vitamin E	2008
Modulation of PPAR receptor subtype selectivity of the ligands: aliphatic chain vs aromatic ring as a spacer between pharmacophore and the lipophilic moiety. Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24 Topics: Butyrates; Chemistry, Pharmaceutical; Dioxanes; Drug Design; Glycine; Humans; Hydrogen; Hydrogen Bonding; Ligands; Models, Chemical; Oxazoles; Peroxisome Proliferator-Activated Receptors; PPAR alpha; Transcriptional Activation	2008
Mass defect filtering on high resolution LC/MS data as a methodology for detecting metabolites with unpredictable structures: identification of oxazole-ring opened metabolites of muraglitazar. Drug metabolism letters, 2007, Volume: 1, Issue:4 Topics: Administration, Oral; Chromatography, High Pressure Liquid; Chromatography, Liquid; Feces; Glycine; Humans; Mass Spectrometry; Oxazoles; PPAR alpha; PPAR gamma	2007
Rapid and sensitive characterization of the metabolite formation enzyme kinetics of radiolabeled drugs using stop-flow liquid radiochromatography. Drug metabolism letters, 2008, Volume: 2, Issue:1 Topics: Buspirone; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Glucuronides; Glycine; Humans; Indoles; Microsomes, Liver; Oxazoles; Reproducibility of Results; Scintillation Counting	2008
PPAR-alpha and PPAR-gamma agonists for type 2 diabetes. Lancet (London, England), 2009, Jul-11, Volume: 374, Issue:9684 Topics: Alkanesulfonates; Clinical Trials, Phase II as Topic; Diabetes Mellitus, Type 2; Glycine; Humans; Hypoglycemic Agents; Oxazoles; Phenylpropionates; PPAR alpha; PPAR gamma; Thiophenes	2009
Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines. The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16 Topics: Ethanolamines; Glycine; Nitrogen; Organotin Compounds; Oxazoles; Propanolamines; Stereoisomerism; Substrate Specificity; Valine	2009
Improving access to FDA reviews and documents. JAMA, 2009, Nov-25, Volume: 302, Issue:20 Topics: Clinical Trials as Topic; Drug Approval; Glycine; Humans; Information Dissemination; Oxazoles; Peer Review, Research; Peroxisome Proliferator-Activated Receptors; Publication Bias; United States; United States Food and Drug Administration	2009
Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453). Journal of medicinal chemistry, 2010, Apr-08, Volume: 53, Issue:7 Topics: Animals; Cell Line; Cricetinae; Crystallography, X-Ray; Drug Discovery; Drug-Related Side Effects and Adverse Reactions; Glycine; Humans; Male; Mice; Models, Molecular; Oxazoles; PPAR alpha; Protein Structure, Tertiary; Substrate Specificity; Transcriptional Activation	2010
Synthesis of 5-amino-oxazole-4-carboxylates from alpha-chloroglycinates. Organic letters, 2010, Sep-03, Volume: 12, Issue:17 Topics: Aluminum; Amines; Carboxylic Acids; Combinatorial Chemistry Techniques; Esters; Glycine; Hydrocarbons, Chlorinated; Lewis Acids; Molecular Structure; Nitriles; Oxazoles; Stereoisomerism	2010
Plasma stability-dependent circulation of acyl glucuronide metabolites in humans: how circulating metabolite profiles of muraglitazar and peliglitazar can lead to misleading risk assessment. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Adult; Animals; Bile; Drug Stability; Glucuronides; Glycine; Hepatocytes; Humans; Macaca fascicularis; Male; Mice; Microsomes, Liver; Oxazoles; Oxidation-Reduction; PPAR alpha; PPAR gamma; Rats; Risk Assessment; Uridine Diphosphate Glucuronic Acid; Young Adult	2011
Catalytic enantioselective synthesis of 4-vinyl-2-trichloromethyloxazoline: an access to enantioenriched vinylglycinol surrogate. The Journal of organic chemistry, 2010, Nov-19, Volume: 75, Issue:22 Topics: Acetamides; Catalysis; Chloroacetates; Cyclization; Glycine; Molecular Structure; Oxazoles; Palladium; Stereoisomerism	2010
Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-19, Volume: 31, Issue:3 Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Benzoates; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxazoles; Pain; Pain Measurement; Pain Perception; Patch-Clamp Techniques; Pyridines; Reactive Oxygen Species; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Spin Labels; Superoxides; Thiazoles; Vocalization, Animal	2011
Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes. Toxicology and applied pharmacology, 2011, Jul-01, Volume: 254, Issue:1 Topics: Alkanesulfonates; Animals; Chromans; Gene Expression Profiling; Genes; Glycine; Hepatocytes; Humans; Male; Oligonucleotide Array Sequence Analysis; Oxazoles; Phenylpropionates; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones; Troglitazone	2011
The development of subcutaneous sarcomas in rodents exposed to peroxisome proliferators agonists: hypothetical mechanisms of action and de-risking attitude. Toxicologic pathology, 2012, Volume: 40, Issue:5 Topics: Adipogenesis; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cell Differentiation; Chromans; Diabetes Mellitus, Type 2; DNA Damage; Glycine; Hypoglycemic Agents; Ion Channels; Mice; Mitochondria; Mitochondrial Proteins; Oxazoles; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pioglitazone; PPAR alpha; PPAR gamma; Rats; RNA-Binding Proteins; Rodentia; Rosiglitazone; Sarcoma; Thermogenesis; Thiazolidinediones; Transcription Factors; Troglitazone; Uncoupling Protein 1	2012
Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models. Arthritis research & therapy, 2013, Apr-17, Volume: 15, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glycine; HEK293 Cells; Humans; In Vitro Techniques; Inflammation; Macrophages; Mice; Oxazoles; PPAR alpha; PPAR gamma; Real-Time Polymerase Chain Reaction	2013
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells. Toxicology and applied pharmacology, 2014, Apr-01, Volume: 276, Issue:1 Topics: Cell Line; Constitutive Androstane Receptor; Drug Evaluation, Preclinical; Fatty Acids, Nonesterified; Fatty Liver; Gene Expression Regulation; Glycine; Humans; Lipid Metabolism; Lipogenesis; Lipotropic Agents; Liver; Liver X Receptors; Non-alcoholic Fatty Liver Disease; Oleic Acid; Orphan Nuclear Receptors; Oxazoles; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; Receptors, Cytoplasmic and Nuclear; Triglycerides	2014
Muraglitazar-eluting bioabsorbable vascular stent inhibits neointimal hyperplasia in porcine iliac arteries. Journal of vascular and interventional radiology : JVIR, 2015, Volume: 26, Issue:1 Topics: Animals; Coated Materials, Biocompatible; Drug-Eluting Stents; Glycine; Hyperplasia; Iliac Artery; Oxazoles; Swine; Tunica Intima	2015
N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology, 2019, Volume: 148 Topics: Animals; Brain Injuries, Traumatic; Cerebral Cortex; Conditioning, Classical; Glycine; Male; Mecamylamine; Mice; Nicotine; Oleic Acids; Oxazoles; PPAR alpha; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tyrosine	2019
Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions. Circulation, 2020, 03-10, Volume: 141, Issue:10 Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; Glucose; Glycated Hemoglobin; Glycine; Government Regulation; Humans; Hypoglycemic Agents; Oxazoles; Phenylbutazone; Practice Guidelines as Topic; Risk; Rosiglitazone; Tolbutamide; United States; United States Food and Drug Administration	2020
Visible-Light-Induced Charge Transfer Enables C Organic letters, 2020, 02-21, Volume: 22, Issue:4 Topics: Cycloaddition Reaction; Epoxy Compounds; Glycine; Light; Molecular Structure; Oxazoles; Oxidation-Reduction	2020