Page last updated: 2024-08-21

oxazoles and glutamine

oxazoles has been researched along with glutamine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199022 (88.00)18.7374
1990's1 (4.00)18.2507
2000's2 (8.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holcenberg, JS1
Berger, AE; Bhuyan, BK; Blowers, CL; Kuentzel, SL; Neil, GL1
Christopherson, RI; Lyons, SD; Sant, ME1
Prajda, N1
Ardalan, B; Deas, M; Jayaram, HN; Johnson, RK1
Horne, AL; Simmonds, MA1
Shreve, PE; Uretsky, NJ2
Sastrasinh, M; Sastrasinh, S2
Cao, L; Chance, WT; Fischer, JE; Foley-Nelson, T; Nelson, JL1
Cao, L; Chance, WT; Fischer, JE; Kim, MW; Nelson, JL1
Huber, KR; Roberts, J; Rosenfeld, H1
Huber, KR; Mayer, EP; Mitchell, DF; Roberts, J1
Aoki, T; Eble, JN; Glover, JL; Sebolt, JS; Weber, G1
Dall'Oglio, GN1
Allen, LM; Corrigan, MV; Meinking, T1
Curthoys, NP; Shapiro, RA1
Aoki, T; Burt, ME; Denton, JE; Faderan, MA; Lui, MS; Prajda, N; Reardon, MA; Sebolt, J; Weber, G; Zhen, YS1
Alonso, MT; Leyland-Jones, B; O'Dwyer, PJ1
Belt, RJ; Haas, CD; Hoogstraten, B; Joseph, U; Taylor, S1
Bower, SG; Tso, JY; Zalkin, H1
Roberts, J; Rosenfeld, H1
Bertrand, L; Hue, L; Krause, U1
Bennett, EM; Cottet, SE; Ealick, SE; Ekstrom, JL; Pegg, AE; Tolbert, WD; Zhang, Y1

Other Studies

25 other study(ies) available for oxazoles and glutamine

ArticleYear
Enhanced effect of an L-glutamine antagonist, L-(alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, by Acinetobacter L-glutaminase-L-asparaginase.
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Acinetobacter; Amino Acids; Animals; Asparaginase; Carcinoma, Ehrlich Tumor; Drug Synergism; Drug Therapy, Combination; Female; Glutaminase; Glutamine; Glycine; Isoxazoles; Lethal Dose 50; Leukemia L1210; Male; Mice; Oxazoles

1979
Studies of the biochemical pharmacology of the fermentation-derived antitumor agent, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    Advances in enzyme regulation, 1978, Volume: 17

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line; Cell Survival; Female; Glutamine; Glycine; Isoxazoles; Leukemia L1210; Leukemia P388; Macromolecular Substances; Male; Mice; Oxazoles; Sex Factors; Thymidine; Uridine; Valine

1978
Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Animals; Azaserine; Azo Compounds; Carbon-Nitrogen Ligases; Cell Line; Chromatography, High Pressure Liquid; Diazooxonorleucine; Glutamine; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Isoxazoles; Leukemia L1210; Ligases; Mice; Nucleotides; Oxazoles; Spectrophotometry, Ultraviolet

1990
Enzyme targets of antiglutamine agents in cancer chemotherapy.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Animals; Anthranilate Synthase; Antibiotics, Antineoplastic; Azaserine; Drug Synergism; Glutamine; Isoxazoles; Liver; Liver Neoplasms, Experimental; Nitrogenous Group Transferases; Oxazoles; Phosphoribosyl Pyrophosphate; Rats; Ribonucleotides; Transferases

1985
Mechanism of resistance of a variant of P388 leukemia to L-(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Cancer research, 1985, Volume: 45, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Drug Resistance; Genetic Variation; Glutamine; Isoxazoles; Kinetics; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Oxazoles; Phosphoribosyl Pyrophosphate

1985
The pharmacology of quisqualate and AMPA in the cerebral cortex of the rat in vitro.
    Neuropharmacology, 1989, Volume: 28, Issue:10

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; In Vitro Techniques; Kynurenic Acid; Male; Neuromuscular Depolarizing Agents; Oxadiazoles; Oxazoles; Pentobarbital; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine

1989
AMPA, kainic acid, and N-methyl-D-aspartic acid stimulate locomotor activity after injection into the substantia innominata/lateral preoptic area.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1

    Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Basal Ganglia; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Ibotenic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Oxazoles; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Substantia Innominata

1989
Effect of acivicin on glutamine transport by rat renal brush border membrane vesicles.
    The Journal of laboratory and clinical medicine, 1986, Volume: 108, Issue:4

    Topics: Amino Acids; Animals; Biological Transport; gamma-Glutamyltransferase; Glucose; Glutamine; In Vitro Techniques; Isoxazoles; Kidney Cortex; Microvilli; Oxazoles; Rats

1986
Role of quisqualic acid receptors in the hypermotility response produced by the injection of AMPA into the nucleus accumbens.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:2

    Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Glutamates; Glutamine; Ibotenic Acid; Injections; Kainic Acid; Locomotion; Male; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug

1988
Acivicin reduces tumor growth during total parenteral nutrition (TPN).
    Surgery, 1987, Volume: 102, Issue:2

    Topics: Animals; Antimetabolites; Body Weight; Glutamine; Isoxazoles; Male; Neoplasm Transplantation; Oxazoles; Parenteral Nutrition, Total; Rats; Rats, Inbred F344; Sarcoma, Experimental; Soft Tissue Neoplasms

1987
The effects of acivicin on glutamine transport by renal basolateral membrane vesicles.
    Contributions to nephrology, 1988, Volume: 63

    Topics: Alanine; Animals; Biological Transport; Cell Membrane; Glutamine; Isoxazoles; Kidney; Oxazoles; Rats

1988
Reduction of tumor growth following treatment with a glutamine antimetabolite.
    Life sciences, 1988, Volume: 42, Issue:1

    Topics: Amino Acids; Animals; Antibiotics, Antineoplastic; Antimetabolites; Body Weight; Energy Intake; Glutamine; Isoxazoles; Male; Methylcholanthrene; Oxazoles; Rats; Rats, Inbred F344; Sarcoma, Experimental

1988
Uptake of glutamine antimetabolites 6-diazo-5-oxo-L-norleucine (DON) and acivicin in sensitive and resistant tumor cell lines.
    International journal of cancer, 1988, May-15, Volume: 41, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Azo Compounds; Biological Transport; Colonic Neoplasms; Diazooxonorleucine; Drug Resistance; Glutamine; Humans; Isoxazoles; Kinetics; Leukemia P388; Lung Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Tumor Cells, Cultured

1988
Cell cycle phase perturbations by 6-diazo-5-oxo-L-norleucine and acivicin in normal and neoplastic human cell lines.
    British journal of cancer, 1987, Volume: 55, Issue:6

    Topics: Antimetabolites; Azo Compounds; Cell Cycle; Cell Line; Colonic Neoplasms; Diazooxonorleucine; Drug Evaluation, Preclinical; Glutaminase; Glutamine; Humans; Isoxazoles; Lung Neoplasms; Neoplasms, Experimental; Oxazoles

1987
Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Antibiotics, Antineoplastic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Colon; Colonic Neoplasms; Glutamine; Humans; Isoxazoles; Kinetics; Ligases; Oxazoles

1985
[Deadyn: treatment of behavior disorders].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1967, Apr-03, Volume: 91, Issue:2

    Topics: Central Nervous System Stimulants; Child; Child Behavior Disorders; Child, Preschool; Glutamine; Humans; Male; Oxazoles; Pemoline

1967
Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase.
    Chemico-biological interactions, 1981, Volume: 33, Issue:2-3

    Topics: Anilides; Animals; Cattle; gamma-Glutamyltransferase; Glutamates; Glutamine; Glycine; In Vitro Techniques; Isoxazoles; Kidney; Kinetics; Oxazoles

1981
Differential effect of AT-125 on rat renal glutaminase activities.
    FEBS letters, 1981, Oct-12, Volume: 133, Issue:1

    Topics: Ammonia; Animals; gamma-Glutamyltransferase; Glutaminase; Glutamine; Glycine; Isoxazoles; Kidney; Kinetics; Male; Oxazoles; Phosphates; Rats

1981
Multi-enzyme-targeted chemotherapy by acivicin and actinomycin.
    Advances in enzyme regulation, 1982, Volume: 20

    Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Dactinomycin; Deoxyribonucleotides; Glutamine; Humans; Isoxazoles; Liver Neoplasms, Experimental; Oxazoles; Rats; Rats, Inbred Strains; Ribonucleotides; Sarcoma, Experimental

1982
Acivicin: a new glutamine antagonist in clinical trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites; Dose-Response Relationship, Drug; Drug Evaluation; Female; Glutamine; Half-Life; Humans; Isoxazoles; Kinetics; Leukemia, Experimental; Liver Neoplasms, Experimental; Macaca mulatta; Male; Mice; Neoplasms; Oxazoles; Purines; Pyrimidines; Sarcoma, Experimental

1984
Phase I evaluation of AT-125 single dose every three weeks.
    Investigational new drugs, 1984, Volume: 2, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Central Nervous System; Drug Administration Schedule; Drug Evaluation; Glutamine; Humans; Isoxazoles; Middle Aged; Neoplasms; Oxazoles

1984
Mechanism of inactivation of glutamine amidotransferases by the antitumor drug L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    The Journal of biological chemistry, 1980, Jul-25, Volume: 255, Issue:14

    Topics: Anthranilate Synthase; Binding, Competitive; Glutamate Synthase; Glutamine; Glycine; Isoxazoles; Kinetics; Nitrogenous Group Transferases; Oxazoles; Serratia marcescens; Transferases

1980
Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.
    Cancer research, 1981, Volume: 41, Issue:4

    Topics: Amidohydrolases; Animals; Asparagine; Azo Compounds; Cell Line; Diazooxonorleucine; DNA; Glutamine; Glycine; Isoxazoles; Kinetics; Leukemia L1210; Mice; Oxazoles; Temperature

1981
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.
    European journal of biochemistry, 2002, Volume: 269, Issue:15

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Glutamine; Hepatocytes; Male; Marine Toxins; Multienzyme Complexes; Okadaic Acid; Oligomycins; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Ribonucleotides; Ribosomal Protein S6 Kinases; Serine; Sirolimus

2002
Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.
    Biochemistry, 2003, Mar-04, Volume: 42, Issue:8

    Topics: Adenosylmethionine Decarboxylase; Alanine; Binding Sites; Buffers; Catalysis; Computer Simulation; Crystallography, X-Ray; Enzyme Precursors; Glutamine; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Oxazoles; Oxygen; Protein Processing, Post-Translational; Putrescine; Serine; Tromethamine

2003