oxazoles has been researched along with gamma-aminobutyric acid in 220 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 210 (95.45) | 18.7374 |
| 1990's | 2 (0.91) | 18.2507 |
| 2000's | 2 (0.91) | 29.6817 |
| 2010's | 3 (1.36) | 24.3611 |
| 2020's | 3 (1.36) | 2.80 |
| Authors | Studies |
|---|---|
| Gale, KN; Guidotti, A | 1 |
| Waddington, JL | 1 |
| Kamioka, T; Matsui, Y | 1 |
| Chase, TN; Crayton, JW; Tamminga, CA | 1 |
| Arnt, J; Krogsgaard-Larsen, P; Magelund, G; Scheel-Krüger, J | 1 |
| Kuhar, MJ; Niehoff, DL; Palacios, JM | 1 |
| Crossman, AR; Lee, LA; Longman, DA; Slater, P | 1 |
| Baker, HF; Ridley, RM; Scraggs, PR | 1 |
| Charlton, M; Goldblatt, D; Joynt, RJ; Shoulson, I | 1 |
| Chase, TN; Frohman, LA; Neophytides, A; Tamminga, CA | 1 |
| Costa, E; Guidotti, A; Naik, SR | 1 |
| Curtis, DR; Johnston, GA; Krogsgaard-Larsen, P; Lodge, D | 1 |
| Beaumont, K; Chilton, WS; Enna, SJ; Yamamura, HI | 1 |
| Snodgrass, SR | 1 |
| Martin, IL; Mitchell, PR | 1 |
| Fang, VS; Meltzer, HY; Simonovic, M | 1 |
| Arnt, J; Krogsgaard-Larsen, P | 2 |
| Longman, DA; Slater, P | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L; Schmitt, G | 2 |
| Di Chiara, G; Morelli, M; Piacente, B; Porceddu, ML | 1 |
| Matthews, WD; McCafferty, GP | 1 |
| Azanza, MJ; Walker, RJ | 1 |
| Risley, EA; Williams, M | 2 |
| Andén, NE; Grabowska-Andén, M; Wachtel, H | 1 |
| Roberts, E; Salvaterra, P; Wang, YJ | 1 |
| Curtis, DR; Hjeds, H; Johnston, GA; Krogsgaard-Larsen, P; Lodge, D | 1 |
| Enna, SJ; Maggi, A | 1 |
| Baldessarini, RJ; Herschel, M | 1 |
| Maurer, R | 2 |
| Jenner, P; Leigh, N; Marsden, CD; Reavill, C | 1 |
| Betti, R; Cocchi, D; Frigerio, C; Krogsgaard-Larsen, P; Locatelli, V; Müller, EE; Racagni, G | 1 |
| Bartholini, G; Scatton, B | 1 |
| Cross, AJ; Waddington, JL | 2 |
| Gross, DM; Sweet, CS; Wenger, HC | 1 |
| Karobath, M; Lippitsch, M | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L | 3 |
| Andrews, PR; Johnston, GA | 1 |
| Grossman, SP; Kelly, J; Rothstein, J | 1 |
| Johnston, GA; Kennedy, SM; Lodge, D | 1 |
| Curtis, DR; Johnston, GA; Lodge, D | 1 |
| Chan-Palay, V | 1 |
| Boissier, JR; Dumont, C; Oberlander, C | 1 |
| Cools, AR; Scheel-Krũger, J; van Wel, PM | 1 |
| Koella, WP; Olpe, HR | 1 |
| Arnt, J; Christensen, AV; Scheel-Krüger, J | 2 |
| Bacino, CB; Martin, GE; Papp, NL | 1 |
| Jobert, A; Soubrié, P; Thiébot, MH | 1 |
| Delini-Stula, A; Vassout, A | 1 |
| Depoortere, H; Lloyd, KG; Worms, P | 1 |
| Hori, N; Ikeda, K; Roberts, E | 1 |
| Leach, MJ; Wilson, JA | 1 |
| Yarbrough, GG | 1 |
| Johnston, GA; Krogsgaard-Larsen, P | 2 |
| Gower, M; MacNeil, D; Szymanska, I | 1 |
| Carlà, V; Giotti, A; Magnani, M; Sgaragli, GP | 1 |
| Cools, AR; Honig, W; Scheel-Krüger, J | 1 |
| Biggio, G; Casu, M; Corda, MG; Gessa, GL; Vernaleone, F | 1 |
| Gorecki, DK; Peesker, SJ; Wood, JD | 1 |
| Cheney, DL; Costa, E; Zsilla, G | 1 |
| Belhage, B; Hansen, GH; Meier, E; Schousboe, A | 3 |
| Gonsalves, SF; Harbaugh, RE; Krogsgaard-Larsen, P; Schousboe, A; Twitchell, B | 1 |
| Weiss, S | 1 |
| Agmo, A; Paredes, R; Soria, P | 1 |
| Hillman, CC; Ornstein, PL; Salhoff, CR; Schoepp, DD | 1 |
| Einspahr, FJ; McGovren, JP; Piercey, MF; Schreur, PJ; Tang, AH; VonVoigtlander, PF; Williams, MG | 1 |
| Liske, S; Morris, ME | 1 |
| Cosi, C; Wood, PL | 1 |
| Spealman, RD; Wettstein, JG | 1 |
| Byberg, JR; Curtis, DR; Falch, E; Gynther, BD; Hjeds, H; Krogsgaard-Larsen, P; Labouta, IM | 1 |
| Bruno, G; Chase, TN; Cox, C; Fedio, P; Foster, N; Gillespie, M; Hare, TA; Mohr, E; Tamminga, C | 1 |
| Arnerić, SP; Meeley, MP; Reis, DJ; Woo, JI | 1 |
| Bagri, A; Di Scala, G; Sandner, G | 1 |
| Hjeds, H; Krogsgaard-Larsen, P; Sarhan, S; Schousboe, A; Seiler, N | 1 |
| Falch, E; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A | 1 |
| Hikosaka, O; Wurtz, RH | 2 |
| Depaulis, A; Vergnes, M | 2 |
| Chweh, AY; Swinyard, EA; Ulloque, RA | 1 |
| Apud, JA; Masotto, C; Racagni, G | 1 |
| Löscher, W | 1 |
| Brunner, EA; Cheng, SC | 1 |
| Krogsgaard-Larsen, P; Schousboe, A; Wood, JD | 1 |
| Friberg, L; Roland, PE | 1 |
| Drower, EJ; Hammond, DL | 1 |
| Depaulis, A; Liebeskind, JC; Morgan, MM | 1 |
| Zarkovsky, AM | 1 |
| Jørgensen, OS; Meier, E; Schousboe, A | 1 |
| Borsini, F; Evangelista, S; Meli, A | 1 |
| Engler, J; Hjeds, H; Krogsgaard-Larsen, P; Schousboe, A; Wood, JD | 1 |
| Dingledine, R; Korn, SJ | 1 |
| Arbit, E; Fogel, R; Kaplan, RB | 1 |
| Hikosaka, O; Iwamura, Y; Sakamoto, M; Tanaka, M | 1 |
| Cynader, M; Needler, MC; Shaw, C | 2 |
| Jensen, MS; Lambert, JD | 1 |
| Kamp, CW; Morgan, WW | 1 |
| Hösli, E; Hösli, L; Möhler, H; Richards, JG | 1 |
| Brecha, N; Yazulla, S | 2 |
| Chweh, A; Ebadi, M | 1 |
| Ishida, M; Shinozaki, H | 2 |
| Collins, JF; Karobath, M; Mannonen, A; Supavilai, P | 1 |
| Forchetti, MC; Guidotti, A; Krogsgaard-Larsen, P; Moroni, F | 1 |
| Karobath, M; Supavilai, P | 1 |
| Ostrovskaia, RU | 1 |
| Chase, TN; Denaro, A; Durso, R; Ruggeri, S; Tamminga, CA | 1 |
| Degener, P; Krause, DN; Roberts, E; Wong, E | 1 |
| Edvinsson, L; Larsson, B; Skärby, T | 1 |
| Hösli, E; Hösli, L | 1 |
| DeFeudis, FV | 2 |
| Cananzi, AR; Costa, E; Guidotti, A | 1 |
| DeFeudis, FV; Devilliers, G; Mandel, P; Sarliéve, LL; Varga, V | 1 |
| Ito, Y; Kurihara, E; Kuriyama, K; Yoneda, Y | 1 |
| Besser, GM; Delitala, G; Grossman, A; Yeo, T | 1 |
| Gardell, MA; Neale, JH; Shibla, DB | 1 |
| Barker, JL; Mathers, DA | 1 |
| Yazulla, S | 1 |
| Aaes-Jørgensen, T; Bøgesø, KP; Krogsgaard-Larsen, P; Mikkelsen, H; Schultz, B | 1 |
| Mitchell, CK; Redburn, DA | 1 |
| Brehm, L; Krogsgaard-Larsen, P; Schaumburg, K | 1 |
| Goetz, IE; Hamel, E; Roberts, E | 1 |
| Falch, E; Krogsgaard-Larsen, P | 1 |
| Ho, IK; Nabeshima, T; Sivam, SP | 1 |
| Blavet, N; Clostre, F; De Feudis, FV | 1 |
| Jordan, CC; Matus, AI; Piotrowski, W; Wilkinson, D | 1 |
| Barker, JL; Jackson, MB; Lecar, H; Mathers, DA | 1 |
| Agardh, E; Ehinger, B | 1 |
| Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ | 1 |
| Cagan, RH; Quinn, MR | 1 |
| Armstrong, DR; Breckenridge, RJ; Suckling, CJ | 1 |
| Christensen, AV; Krogsgaard-Larsen, P; Svendsen, O | 1 |
| Blavet, N; DeFeudis, FV | 1 |
| Patel, SC; Peck, EJ | 1 |
| Frey, KA; Pan, HS; Penney, JB; Young, AB | 1 |
| Curtis, DR; Falch, E; Jacobsen, P; Krogsgaard-Larsen, P; Leah, JD; Mikkelsen, H; Peet, MJ | 1 |
| Rägo, LK; Zarkovsky, AM | 1 |
| Lucacchini, A; Martini, C; Rigacci, T | 1 |
| Johnston, GA; Skerritt, JH | 1 |
| Quinn, MR; Somerville, RA | 1 |
| Gonzalez, LP; Hettinger, MK | 1 |
| Dafny, N; Reyes-Vázquez, C | 1 |
| Besson, MJ; Gauchy, C; Glowinski, J; Kemel, ML | 1 |
| Altmann, H; Dose, M; Emrich, HM; von Zerssen, D | 1 |
| Bjørndal, N; Christensson, E; Gerlach, J | 1 |
| Bereksi, B; Boggio, V; Guilland, JC; Klepping, J; Mack, G; Noirot, P | 1 |
| Köhler, C; McBean, GJ; Roberts, PJ; Schwarcz, R; Steiner, HX | 1 |
| Goebel, DJ; McReynolds, JS; Pourch, RG | 1 |
| Sarhan, S; Seiler, N | 1 |
| Dean, P; Redgrave, P; Taha, EB | 1 |
| Allen, CN; Crawford, IL | 1 |
| Brennan, TJ; Haywood, JR; Morris, M | 1 |
| Besson, MJ; Gauchy, C; Glowinski, J; Kemel, ML; Romo, R | 1 |
| Goebel, DJ; Pourcho, RG | 1 |
| Di Scala, G; Karli, P; Schmitt, P | 1 |
| Besson, MJ; Chéramy, A; Gauchy, C; Glowinski, J; Kemel, ML; Romo, R | 1 |
| Gluckman, PD; Johnston, BM | 1 |
| Childs, JA; Gale, K | 1 |
| Kelly, PA; McCulloch, J | 2 |
| Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, WA | 1 |
| Albala, BJ; Moshé, SL | 1 |
| Helén, P; London, ED | 1 |
| Horton, R; Meldrum, B | 1 |
| Kaakkola, S; Kääriäinen, I | 1 |
| Gent, JP; Phillips, NI | 1 |
| Mandel, P; Puglisi-Allegra, S | 1 |
| Moises, HC; Waterhouse, BD; Woodward, DJ; Yeh, HH | 1 |
| Claperon, N; Durussel, JJ; Rossignol, P | 1 |
| Scholfield, CN | 1 |
| Madsen, SM | 1 |
| Harris, RA; Rohde, BH | 1 |
| Ho, IK; Sivam, SP | 1 |
| Cappelletti, G; Cavagnini, F; Dubini, A; Invitti, C; Pinto, M; Polli, EE | 1 |
| Kuhar, MJ; London, ED; Palacios, JM; Rapoport, SI | 2 |
| Blanks, JC; Roffler-Tarlov, S | 1 |
| DeFeudis, FV; Grognet, A; Hertz, F | 1 |
| Christensen, AV; Larsen, JJ | 1 |
| Bosh, TK; Fung, YK; Grassman, DR; Novin-Baheran, A | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L; Rebel, G; Sarliève, LL; Schmitt, G; Varga, V | 1 |
| Pourcho, RG | 1 |
| Constanti, A; Nistri, A | 1 |
| Menon, MK | 1 |
| Bergstrom, DA; Walters, JR; Waszczak, BL | 1 |
| Fukuda, H; Kaneko, T; Ono, H | 1 |
| Eng, N; Walters, JR; Waszczak, BL | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L; Sarliève, LL | 1 |
| Korf, J; van der Heyden, JA; Venema, K | 1 |
| DeFeudis, FV; Geffard, M; Mandel, P; Ossola, L; Varga, V | 1 |
| Hruska, RE; Walters, JR; Waszczak, BL | 1 |
| Cooper, BR; Howard, JL; Ingold, K; Maxwell, RA; Soroko, F; White, HL | 1 |
| Kuriyama, K; Yoneda, Y | 1 |
| DeFeudis, FV; Geffard, M; Mandel, P; Varga, V | 1 |
| Schaeffer, JM | 1 |
| Persson, B | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L; Schmitt, G; Wolff, P | 1 |
| Baraczka, K; Sperk, G | 1 |
| Fukunaga, K; Kano, M; Konnerth, A | 1 |
| Deadwyler, SA; Hampson, RE; Weiner, JL; Zhuang, SY | 1 |
| Cao, LH; Yang, XL; Yu, YC | 1 |
| Chen, W; Ke, JB; Wang, Z; Yang, XL | 1 |
| Antoni, FA; Barkóczy, J; Bartha, F; Bogár, F; Gacsályi, I; Ling, I; Martinek, TA; Megyeri, K; Mihalik, B; Pálvölgyi, A | 1 |
| Antoni, FA; Barkóczy, J; Belelli, D; Brown, AR; Etherington, LA; Gacsályi, I; Gunn, BG; Kertész, S; Lambert, JJ; Ling, I; Livesey, MR; Mihalik, B; Monteiro, O; Pallagi, K; Pálvölgyi, A; Spedding, M; Varga, P | 1 |
| Audoli-Inthavong, ML; Bassetti, CL; Chabriat, H; Hermann, DM; Lambert, E; Marx, U; Sors, A; Wattez, M | 1 |
| Amodeo, P; Belardo, C; Boccella, S; Calignano, A; Cristiano, C; de Novellis, V; Di Marzo, V; Guida, F; Iannotta, M; Iannotti, FA; Infantino, R; Luongo, L; Maione, S; Marabese, I; Paino, S; Palazzo, E; Ricciardi, F; Vitale, RM | 1 |
| Casero, JL; d'Ardhuy, XL; Derks, M; Fontoura, P; Goeldner, C; Hernandez, MC; Hipp, JF; Khwaja, O; Kishnani, PS; Lennon-Chrimes, S; Noeldeke, J; Pellicer, S; Skotko, BG; Squassante, L; Visootsak, J; Wandel, C | 1 |
7 review(s) available for oxazoles and gamma-aminobutyric acid
| Article | Year |
|---|---|
GABA receptor agonists: relationship between structure and biological activity in vivo and in vitro.
Topics: Animals; gamma-Aminobutyric Acid; Kinetics; Muscimol; Oxazoles; Receptors, Drug; Structure-Activity Relationship; Substantia Nigra | 1979 |
GABA uptake inhibitors: relevance to antiepileptic drug research.
Topics: Animals; Anticonvulsants; Brain; Epilepsy; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Oxazoles | 1987 |
Binsing studies with muscimol; relation ty synaptic gamma-aminobutyrate receptors.
Topics: Animals; Astacoidea; Autoradiography; Blood Vessels; Brain; Cattle; Cerebellum; Culture Techniques; Freezing; gamma-Aminobutyric Acid; Kinetics; Muscimol; Muscles; Oxazoles; Pia Mater; Polyethylene Glycols; Rats; Receptors, Neurotransmitter; Sodium; Subcellular Fractions; Substrate Specificity | 1980 |
Physiological and behavioral studies with muscimol.
Topics: Animals; Behavior; Behavior, Animal; Blood-Brain Barrier; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Humans; Learning; Memory; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1980 |
THIP, isoguvacine, isoguvacine oxide, and related GABA agonists.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Oxazoles; Pipecolic Acids; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution | 1981 |
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure.
Topics: Agaricales; Amanita; Animals; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Structural; Molecular Conformation; Muscimol; Nipecotic Acids; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1981 |
Pharmacodynamic effects and possible therapeutic uses of THIP, a specific GABA-agonist.
Topics: Analgesics; Animals; Brain; gamma-Aminobutyric Acid; Humans; Isoxazoles; Methylphenidate; Neurons; Oxazoles; Stereotyped Behavior; Synaptic Transmission | 1982 |
6 trial(s) available for oxazoles and gamma-aminobutyric acid
| Article | Year |
|---|---|
Huntington's disease: treatment with muscimol, a GABA-mimetic drug.
Topics: Activities of Daily Living; Adolescent; Adult; Clinical Trials as Topic; Cognition; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Huntington Disease; Male; Middle Aged; Muscimol; Oxazoles; Placebos | 1978 |
GABA-agonist therapy for Alzheimer's disease.
Topics: Alzheimer Disease; Clinical Trials as Topic; gamma-Aminobutyric Acid; Humans; Isoxazoles; Middle Aged; Neuropsychological Tests; Oxazoles; Somatostatin | 1986 |
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Middle Aged; Mood Disorders; Oxazoles; Oxcarbazepine; Schizophrenia; Valproic Acid | 1983 |
Effects of gamma aminobutyric acid (GABA) and muscimol on endocrine pancreatic function in man.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Female; gamma-Aminobutyric Acid; Glucagon; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Muscimol; Oxazoles | 1982 |
Safety and efficacy of GABA
Topics: Adult; Aged; Aged, 80 and over; Benzodiazepines; Brain; Brain Ischemia; Double-Blind Method; Female; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Oxazoles; Stroke; Treatment Outcome | 2020 |
A randomized, double-blind, placebo-controlled phase II trial to explore the effects of a GABA
Topics: Adolescent; Child; Child, Preschool; Down Syndrome; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Morpholines; Oxazoles; Pyridines; Quality of Life; Treatment Outcome; Young Adult | 2022 |
207 other study(ies) available for oxazoles and gamma-aminobutyric acid
| Article | Year |
|---|---|
GABA-mediated control of rat neostriatal tyrosine hydroxylase revealed by intranigral muscimol.
Topics: Aminobutyrates; Animals; Bicuculline; Caudate Nucleus; Corpus Striatum; Dopamine; Enzyme Activation; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Kinetics; Neural Pathways; Olfactory Bulb; Oxazoles; Pimozide; Pteridines; Quaternary Ammonium Compounds; Rats; Substantia Nigra; Tyrosine 3-Monooxygenase | 1976 |
GABA-like properties of flurazepam and baclofen suggested by rotational behaviour following unilateral intranigral injection: a comparison with the GABA agonist muscimol [proceedings].
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Baclofen; Behavior; Flurazepam; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Rats; Stereotyped Behavior; Substantia Nigra | 1977 |
Cataleptic and anticataleptic effects of muscimol and gabaculine injected into globus pallidus and substantia nigra, and interactions with haloperidol or benzodiazepines.
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Benzodiazepines; Catalepsy; Corpus Striatum; Cyclohexanecarboxylic Acids; Cyclohexylamines; Drug Interactions; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Homovanillic Acid; Humans; Injections; Male; Muscimol; Oxazoles; Rats; Substantia Nigra; Transaminases | 1978 |
Improvement in tardive dyskinesia after muscimol therapy.
Topics: Adult; Aged; Antipsychotic Agents; Dopamine; Drug Evaluation; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscimol; Oxazoles; Receptors, Dopamine; Schizophrenia; Stimulation, Chemical; Synaptic Transmission | 1979 |
Muscimol and related GABA receptor agonists: the potency of GABAergic drugs in vivo determined after intranigral injection.
Topics: Animals; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Stereotyped Behavior; Substantia Nigra; Time Factors | 1979 |
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
Topics: Age Factors; Animals; Anti-Anxiety Agents; Bromides; Cerebellum; Female; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Polyethylene Glycols; Pregnancy; Rats; Receptors, Drug | 1979 |
Effects of benzodiazepines and barbiturates in a GABA-dependent animal model: interactions with muscimol in the globus pallidus [proceedings].
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Behavior, Animal; Benzodiazepines; Drug Interactions; Female; gamma-Aminobutyric Acid; Globus Pallidus; Muscimol; Oxazoles; Rats | 1979 |
Modification of the behavioural effects of amphetamine by a GABA agonist in a primate species.
Topics: Animals; Behavior, Animal; Callitrichinae; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haplorhini; Humans; Male; Motor Activity; Muscimol; Oxazoles; Stereotyped Behavior | 1979 |
Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.
Topics: Adult; Aged; Chronic Disease; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Kinetics; Male; Middle Aged; Muscimol; Oxazoles; Prolactin; Schizophrenia | 1978 |
Central GABA receptor agonists: comparison of muscimol and baclofen.
Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P | 1976 |
A new class of GABA agonist.
Topics: Action Potentials; Aminobutyrates; Animals; Bicuculline; Biological Transport; Cats; gamma-Aminobutyric Acid; Interneurons; Isonicotinic Acids; Isoxazoles; Molecular Conformation; Neural Inhibition; Oxazoles; Receptors, Neurotransmitter; Spinal Cord; Structure-Activity Relationship; Synaptic Transmission | 1977 |
Muscimol binding in rat brain: association with synaptic GABA receptors.
Topics: Aminobutyrates; Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Polyethylene Glycols; Rats; Receptors, Neurotransmitter; Sodium | 1978 |
Use of 3H-muscimol for GABA receptor studies.
Topics: Aminobutyrates; Animals; Bicuculline; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Oxazoles; Potassium; Rats; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes | 1978 |
Is GABA release modulated by presynaptic receptors?
Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Oxazoles; Picrotoxin; Potassium; Rats; Receptors, Neurotransmitter; Taurine | 1978 |
The effect of muscimol on prolactin secretion in male rats.
Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperidol; Male; Methyltyrosines; Muscimol; Oxazoles; Premedication; Prolactin; Rats; Receptors, Neurotransmitter | 1978 |
GABA agonists and potential antagonists related to muscimol.
Topics: Animals; Dose-Response Relationship, Drug; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Stereotyped Behavior; Substantia Nigra | 1979 |
Effects of diazepam and muscimol on GABA-mediated neurotransmission: interactions with inosine and nicotinamide.
Topics: Animals; Corpus Striatum; Diazepam; Drug Interactions; Female; gamma-Aminobutyric Acid; Globus Pallidus; Inosine; Muscimol; Niacinamide; Oxazoles; Rats; Synaptic Transmission; Time Factors | 1979 |
High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain.
Topics: Animals; Brain; Brain Chemistry; Culture Techniques; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Subcellular Fractions | 1979 |
Opposite turning effects of dainic and ibotenic acid injected in the rat substantia nigra.
Topics: Animals; Dose-Response Relationship, Drug; Functional Laterality; gamma-Aminobutyric Acid; Glutamates; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Oxazoles; Posture; Pyrrolidines; Rats; Receptors, Neurotransmitter; Substantia Nigra | 1979 |
Anticonvulsant activity of muscimol against seizures induced by impairment of GABA-mediated neurotransmission.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Synaptic Transmission | 1979 |
Gaba-receptor interactions; models in Helix aspersa neurons.
Topics: Alanine; Aminobutyrates; Animals; Crotonates; gamma-Aminobutyric Acid; Helix, Snails; Models, Biological; Molecular Conformation; Neurons; Oxazoles; Quaternary Ammonium Compounds; Receptors, Drug; Snails; Structure-Activity Relationship | 1975 |
Characterization of the binding of [3H]muscimol, a potent gamma-aminobutyric acid agonist, to rat brain synaptosomal membranes using a filtration assay.
Topics: Animals; Binding, Competitive; Brain; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Muscimol; Oxazoles; Rats; Receptors, Drug; Synaptic Membranes; Tissue Distribution | 1979 |
Effects of the GABA receptor agonist muscimol on the turnover of brain dopamine and on the motor activity of rats.
Topics: Animals; Brain; Cell Nucleus; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Norepinephrine; Oxazoles; Rats | 1979 |
Characterization of [3H]muscimol binding to mouse brain membranes.
Topics: Animals; Binding, Competitive; Brain; Detergents; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Mice; Muscimol; Osmolar Concentration; Oxazoles; Receptors, Drug | 1979 |
Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.
Topics: Animals; Brain; Cats; Cell Membrane; gamma-Aminobutyric Acid; Muscimol; Neurons; Oxazoles; Oxazolidinones; Rats; Receptors, Drug; Spinal Cord; Structure-Activity Relationship | 1979 |
Enhancement of the binding of 3H-diazepam to rat brain membranes in vitro by SQ 20009, A novel anxiolytic, gamma-aminobutyric acid (GABA) and muscimol.
Topics: Animals; Bicuculline; Brain; Diazepam; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nicotinic Acids; Oxazoles; Picrotoxin; Rats; Stimulation, Chemical | 1979 |
Characteristics of muscimol accumulation in mouse brain after systemic administration.
Topics: Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; History, 18th Century; Injections, Intravenous; Mice; Muscimol; Oxazoles; Phenobarbital; Time Factors | 1979 |
Evidence for two types of binding of 3H-gaba and 3H-muscimol in rat cerebral cortex and cerebellum.
Topics: Animals; Brain Stem; Cerebellum; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Organ Specificity; Oxazoles; Radioligand Assay; Rats; Receptors, Drug; Substrate Specificity; Synaptosomes | 1979 |
The GABA agonist THIP a muscimol analogue, does not interfere with the benzodiazepine binding site on rats cortical membranes.
Topics: Animals; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Taurine | 1979 |
Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components.
Topics: Animals; gamma-Aminobutyric Acid; Male; Movement; Muscimol; Organ Specificity; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1979 |
Dual gamma-aminobutyric acid control of prolactin secretion in the rat.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Methyltyrosines; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats | 1979 |
Increase in striatal acetylcholine levels by GABA mimetic drugs: lack of involvement of the nigro-striatal dopaminergic neurons.
Topics: Acetylcholine; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Oxazoles; Rats | 1979 |
Baclofen and muscimol: behavioural and neurochemical sequelae of unilateral intranigral administration and effects on 3H-GABA receptor binding.
Topics: Aminobutyrates; Animals; Baclofen; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxydopamines; Injections; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Substantia Nigra; Time Factors | 1979 |
Central antihypertensive properties of muscimol and related gamma-aminobutyric acid agonists and the interaction of muscimol with baroreceptor reflexes.
Topics: Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Oxazoles; Pressoreceptors; Reflex; Vasomotor System | 1979 |
THIP and isoguvacine are partial agonists of GABA-stimulated benzodiazepine receptor binding.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Drug | 1979 |
[3H]Muscimol binding to rat cerebellar membranes.
Topics: Animals; Cell Membrane; Cerebellum; Female; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Tritium | 1979 |
More muscimol binding sites than GABA binding sites in a particulate fraction of rat brain.
Topics: Animals; Binding Sites; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Oxazoles; Rats | 1979 |
Comparison of the "specific" binding of [3H]GABA and [3H]muscimol to a particulate fraction of rat brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Nerve Tissue Proteins; Oxazoles; Protein Binding; Rats; Subcellular Fractions | 1979 |
Conformational analysis of muscimol, a GABA agonist.
Topics: Bicuculline; Binding Sites; gamma-Aminobutyric Acid; Isoxazoles; Models, Molecular; Molecular Conformation; Muscimol; Oxazoles; Quantum Theory | 1979 |
GABA and hypothalamic feeding systems. I. Topographic analysis of the effects of microinjections of muscimol.
Topics: Animals; Bicuculline; Brain Mapping; Digestive System; Eating; Female; gamma-Aminobutyric Acid; Gastric Juice; Hypothalamus; Hypothalamus, Middle; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats | 1979 |
Muscimol uptake, release and binding in rat brain slices.
Topics: Alanine; Animals; Binding, Competitive; Biological Transport; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Oxazoles; Rats; Receptors, Drug | 1978 |
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord.
Topics: Aminobutyrates; Animals; Biological Transport; Cats; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons; Nipecotic Acids; Oxazoles; Spinal Cord | 1978 |
Recent advances in the morphological localization of gamma-aminobutyric acid receptors in the cerebellum by means of [3H]muscimol.
Topics: Animals; Brain; Cerebellar Nuclei; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Purkinje Cells; Rats | 1979 |
Rotational behaviour after unilateral intranigral injection of muscimol in rats.
Topics: Aminobutyrates; Animals; Basidiomycota; Behavior; Bicuculline; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Picrotoxin; Rats; Stereotyped Behavior; Substantia Nigra; Time Factors | 1977 |
Muscimol a GABA-agonist injected into the nucleus accumbens increases apomorphine stereotypy and decreases the motility.
Topics: Aminobutyrates; Animals; Apomorphine; Basidiomycota; Behavior; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Motor Activity; Nucleus Accumbens; Oxazoles; Rats; Septal Nuclei; Stereotyped Behavior | 1977 |
The action of muscimol on neurones of the substantia nigra of the rat.
Topics: Animals; Basidiomycota; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Male; Neural Inhibition; Neurons; Oxazoles; Rats; Substantia Nigra | 1978 |
Muscimol differentially facilitates stereotypy but antagonizes motility induced by dopaminergic drugs: a complex GABA-dopamine interaction.
Topics: Animals; Apomorphine; Basidiomycota; Behavior; Cocaine; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Methylphenidate; Methyltyrosines; Mice; Motor Activity; Oxazoles; Stereotyped Behavior | 1978 |
Contralateral turning evoked by the intranigral microinjection of muscimol and other GABA agonists.
Topics: Animals; Behavior; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Ethanolamines; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Muscimol; Oxazoles; Picrotoxin; Putamen; Rats; Stereotyped Behavior; Substantia Nigra | 1978 |
A comparative study of the effects of muscimol and diazepam on the recall of noxious events.
Topics: Animals; Avoidance Learning; Diazepam; Dissociative Disorders; gamma-Aminobutyric Acid; Humans; Male; Memory; Mental Recall; Muscimol; Oxazoles; Rats | 1979 |
Modulatory effects of baclofen muscimol and GABA on interspecific aggressive behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Olfactory Bulb; Oxazoles; Rats | 1978 |
Neuropharmacological spectrum of muscimol.
Topics: Animals; Anticonvulsants; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Humans; Male; Mice; Motor Activity; Muscimol; Muscle Relaxants, Central; Nervous System; Oxazoles; Receptors, Drug | 1979 |
Muscimol, GABA and picrotoxin: effects on membrane conductance of a crustacean neuron.
Topics: Aminobutyrates; Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Mechanoreceptors; Membrane Potentials; Mycotoxins; Neural Inhibition; Neurons; Oxazoles; Picrotoxin; Receptors, Drug; Synaptic Membranes | 1978 |
GABA receptor binding with 3H-muscimol in calf cerebellum.
Topics: Aminobutyrates; Animals; Bicuculline; Cattle; Cerebellum; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Kinetics; Oxazoles; Receptors, Drug | 1978 |
Muscimol antagonizes morphine hypermotility without potentiation of analgesia.
Topics: Analgesia; Analgesics; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Neuromuscular Blocking Agents; Oxazoles | 1978 |
Nipecotic acid and 2,4-diaminobutyric acid enhance the actions of muscimol on cerebral cortical neurons.
Topics: Action Potentials; Amino Acids, Diamino; Aminobutyrates; Animals; Cerebral Cortex; Drug Synergism; Female; gamma-Aminobutyric Acid; Isoxazoles; Mycotoxins; Neurons; Nipecotic Acids; Oxazoles; Rats | 1978 |
Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds.
Topics: Aminobutyrates; Animals; Brain; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Structure-Activity Relationship; Synaptic Membranes | 1978 |
Response of dopamine neurons in substantia nigra to muscimol.
Topics: Animals; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1978 |
Homotaurine and muscimol mimic taurine and GABA effects on muscle tone and temperature regulation.
Topics: Amino Acids; Animals; Body Temperature Regulation; Electroencephalography; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Male; Muscimol; Muscle Tonus; Oxazoles; Rabbits; Taurine | 1978 |
Muscimol antagonizes the ergometrine-induced locomotor activity in nucleus accumbens: evidence for a GABA--dopaminergic interaction.
Topics: Aminobutyrates; Animals; Dopamine; Ergonovine; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Olfactory Bulb; Oxazoles; Rats; Time Factors | 1977 |
Effect of muscimol, a GABA-mimetic agent, on dopamine metabolism in the mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Aminobutyrates; Animals; Brain; Caudate Nucleus; Diazepam; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Homovanillic Acid; Isoxazoles; Male; Mice; Motor Activity; Oxazoles; Phenobarbital | 1977 |
3-Isoxazolidone--an inhibitor of GABA metabolism.
Topics: Aminobutyrates; Animals; Brain; Chickens; Depression, Chemical; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Isoniazid; Isoxazoles; Male; Mice; Oxazoles; Oxazolidinones; Rats; Seizures; Time Factors | 1976 |
Regional changes in the rate of turnover of acetylcholine in rat brain following diazepam or muscimol.
Topics: Acetylcholine; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Isoxazoles; Male; Oxazoles; Quaternary Ammonium Compounds; Rats; Receptors, Drug | 1976 |
Inhibition of GABA uptake in rat brain slices by nipecotic acid, various isoxazoles and related compounds.
Topics: Aminobutyrates; Animals; Biological Transport, Active; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Kinetics; Nipecotic Acids; Oxazoles; Rats; Structure-Activity Relationship | 1975 |
Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells.
Topics: Animals; Anticonvulsants; Cell Differentiation; Cell Membrane; Cells, Cultured; Cerebellum; Colchicine; Cycloheximide; Dactinomycin; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Microscopy, Electron; Monensin; Oxazoles; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Anticonvulsant activity of the glial GABA uptake inhibitor, THAO, in chemical seizures.
Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Isoniazid; Isoxazoles; Male; Nervous System; Neuroglia; Neurotransmitter Uptake Inhibitors; Oxazoles; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1989 |
Two distinct quisqualate receptor systems are present on striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Corpus Striatum; gamma-Aminobutyric Acid; Ibotenic Acid; Inositol Phosphates; Mice; Oxadiazoles; Oxazoles; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter | 1989 |
GABAergic drugs and lordosis behavior in the female rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal; Taurine | 1989 |
CGS-19755 and MK-801 selectively prevent rat striatal cholinergic and gabaergic neuronal degeneration induced by N-methyl-D-aspartate and ibotenate in vivo.
Topics: Animals; Aspartic Acid; Choline O-Acetyltransferase; Cholinergic Fibers; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; gamma-Aminobutyric Acid; Ibotenic Acid; Male; N-Methylaspartate; Nerve Degeneration; Oxazoles; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Animal behavioral and neurochemical effects of the CNS toxic amino acid antitumor agent, acivicin.
Topics: Action Potentials; Amino Acids; Animals; Antibiotics, Antineoplastic; Avoidance Learning; Behavior, Animal; Brain Chemistry; Cats; Discrimination, Psychological; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Macaca mulatta; Male; Mice; Neurons; Oxazoles; Rats; Rats, Inbred F344 | 1989 |
Effects of GABA, THIP, and potassium on excitability of myelinated axons of isolated amphibian spinal roots.
Topics: Anesthetics; Animals; Axons; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Myelin Sheath; Oxazoles; Potassium; Rana catesbeiana; Spinal Cord | 1989 |
Lack of GABAergic modulation of acetylcholine turnover in the rat thalamus.
Topics: Acetylcholine; Animals; Brain Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamus | 1988 |
GABA-related drugs modulate the behavioral effects of lorazepam.
Topics: Animals; Behavior, Animal; Drug Synergism; gamma-Aminobutyric Acid; Isoxazoles; Lorazepam; Male; Oxazoles; Receptors, GABA-A; Saimiri | 1988 |
Temporal development of GABA agonist induced alterations in ultrastructure and GABA receptor expression in cultured cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Microscopy, Electron; Organelles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors | 1987 |
Synthesis and biological activity of a GABAA agonist which has no effect on benzodiazepine binding and of structurally related glycine antagonists.
Topics: Animals; Bicuculline; Brain Chemistry; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Isoxazoles; Oxazoles; Piperidines; Pyrrolidines; Rats; Receptors, GABA-A; Synaptic Membranes | 1987 |
Spontaneous release of endogenous aspartate and glutamate from rat striatal slices is increased following destruction of local neurons by ibotenic acid.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Neurons; Oxazoles; Rats | 1988 |
Effects of unilateral microinjections of GABAergic drugs into the inferior colliculus on auditory evoked potentials and on audiogenic seizure susceptibility.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Bicuculline; Evoked Potentials, Auditory; Functional Laterality; gamma-Aminobutyric Acid; Inferior Colliculi; Isoxazoles; Male; Microinjections; Oxazoles; Rats; Rats, Inbred Strains; Reference Values; Seizures | 1989 |
Amplification by glycine of the anticonvulsant effect of THPO, a GABA uptake inhibitor.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Male; Mice; Neurotransmitter Uptake Inhibitors; Oxazoles; Pentylenetetrazole; Seizures | 1985 |
Modification of saccadic eye movements by GABA-related substances. I. Effect of muscimol and bicuculline in monkey superior colliculus.
Topics: Animals; Bicuculline; Eye Movements; gamma-Aminobutyric Acid; Macaca mulatta; Muscimol; Oxazoles; Saccades; Superior Colliculi; Synaptic Transmission; Visual Fields | 1985 |
Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata.
Topics: Animals; Brain Mapping; Eye Movements; gamma-Aminobutyric Acid; Macaca mulatta; Muscimol; Neural Pathways; Oxazoles; Saccades; Substantia Nigra; Superior Colliculi; Synaptic Transmission | 1985 |
Elicitation of conspecific attack or defense in the male rat by intraventricular injection of a GABA agonist or antagonist.
Topics: Aggression; Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Male; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1985 |
Effects of gamma-aminobutyric acid (GABA) receptor agonists on the neurotoxicity and anticonvulsant activity of barbiturates in mice.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Nervous System; Oxazoles; Receptors, GABA-A; Seizures | 1986 |
Effect of THIP and SL 76002, two clinically experimented GABA-mimetic compounds, on anterior pituitary GABA receptors and prolactin secretion in the rat.
Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Female; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Kinetics; Male; Muscimol; Ovariectomy; Oxazoles; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils.
Topics: Acetates; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Diazepam; Drug Tolerance; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Oxazoles; Valproic Acid | 1986 |
Inducing anesthesia with a GABA analog, THIP.
Topics: Analgesics; Anesthesia, Intravenous; Anesthetics; Animals; Benzodiazepines; gamma-Aminobutyric Acid; Isoxazoles; Ketamine; Male; Mice; Midazolam; Oxazoles; Rats; Rats, Inbred Strains; Sodium Oxybate; Time Factors | 1985 |
Amplification by glycine of the effect of the GABA transport inhibitor THPO on synaptosomal GABA level.
Topics: Amino Acids; Animals; Brain; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Male; Mice; Oxazoles; Synaptosomes | 1988 |
The effect of the GABA-A agonist THIP on regional cortical blood flow in humans. A new test of hemispheric dominance.
Topics: Adolescent; Adult; Behavior; Carotid Arteries; Cerebrovascular Circulation; Dominance, Cerebral; Electroencephalography; gamma-Aminobutyric Acid; Humans; Injections, Intra-Arterial; Isoxazoles; Middle Aged; Neural Inhibition; Oxazoles; Synapses | 1988 |
Gamma-aminobutyric acid agonist-induced alterations in the ultrastructure of cultured cerebellar granule cells is restricted to early development.
Topics: Animals; Cells, Cultured; Cerebellum; Cytoplasm; Endoplasmic Reticulum; gamma-Aminobutyric Acid; Golgi Apparatus; Isoxazoles; Microscopy, Electron; Oxazoles; Rats; Rats, Inbred Strains | 1988 |
GABAergic modulation of nociceptive threshold: effects of THIP and bicuculline microinjected in the ventral medulla of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Microinjections; Oxazoles; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds | 1988 |
GABAergic modulation of the analgesic effects of morphine microinjected in the ventral periaqueductal gray matter of the rat.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Neurons; Nociceptors; Oxazoles; Periaqueductal Gray; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains | 1987 |
Bicuculline-sensitive and insensitive effects of THIP on the binding of [3H]flunitrazepam.
Topics: Animals; Bicuculline; Brain; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoxazoles; Male; Osmolar Concentration; Oxazoles; Rats; Rats, Inbred Strains; Sodium Chloride; Tritium | 1987 |
Effect of repeated treatment with a gamma-aminobutyric acid receptor agonist on postnatal neural development in rats.
Topics: Animals; Antigens, Surface; Brain; Cell Adhesion; Cell Adhesion Molecules; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamate Dehydrogenase; Isoxazoles; Nerve Tissue Proteins; Neurons; Organ Size; Oxazoles; Rats; Rats, Inbred Strains | 1987 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Tissue distribution, metabolism, anticonvulsant efficacy and effect on brain amino acid levels of the glia-selective gamma-aminobutyric acid transport inhibitor 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol in mice and chicks.
Topics: Amino Acids; Animals; Anticonvulsants; Biological Transport; Brain; Chickens; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Liver; Male; Mice; Oxazoles; Tissue Distribution | 1986 |
Prolongation of gamma-aminobutyric acid-mediated inhibitory postsynaptic potentials by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol (THPO).
Topics: Animals; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Iontophoresis; Isoxazoles; Neural Inhibition; Nipecotic Acids; Oxazoles; Rats; Synapses | 1986 |
Central action of gamma-aminobutyric acid ligands to alter basal water and electrolyte absorption in the rat ileum.
Topics: Animals; Bicuculline; Biological Transport; Body Fluids; Cholinergic Fibers; Electrolytes; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; Intestinal Absorption; Ligands; Male; Muscimol; Oxazoles; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1985 |
Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey.
Topics: Animals; Brain Diseases; Brain Mapping; Female; gamma-Aminobutyric Acid; Hand; Macaca; Motor Skills; Muscimol; Oxazoles; Somatosensory Cortex | 1985 |
Characteristics and distribution of muscimol binding sites in cat visual cortex.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Muscimol; Oxazoles; Receptors, GABA-A; Tissue Distribution; Tritium; Visual Cortex | 1984 |
Ontogenesis of muscimol binding sites in cat visual cortex.
Topics: Animals; Binding Sites; Cats; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neural Inhibition; Oxazoles; Receptors, GABA-A; Visual Cortex | 1984 |
Modulation of the responses to the GABA-mimetics, THIP and piperidine-4-sulphonic acid, by agents which interact with benzodiazepine receptors. An electrophysiological study on cultured mouse neurones.
Topics: Animals; Benzodiazepines; Carbolines; Cells, Cultured; Convulsants; Electrophysiology; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Mice; Midazolam; Neurons; Oxazoles; Piperidines; Receptors, GABA-A | 1984 |
Some barbiturates enhance the effect of muscimol on dopamine turnover in the rat retina.
Topics: Animals; Barbital; Barbiturates; Convulsants; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Oxazoles; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Retina; Sesterterpenes | 1980 |
Autoradiographic localization of binding sites for [3H]gamma-aminobutyrate, [3H]muscimol,(+)[3H]bicuculline methiodide and [3H] flunitrazepam in cultures of rat cerebellum and spinal cord.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Bicuculline; Binding Sites; Cells, Cultured; Cerebellum; Female; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Pregnancy; Rats; Receptors, Drug; Spinal Cord; Tritium | 1980 |
Binding and uptake of the GABA analogue, 3H-muscimol, in the retinas of goldfish and chicken.
Topics: Animals; Autoradiography; Chickens; gamma-Aminobutyric Acid; Goldfish; Muscimol; Neurons; Neurotransmitter Agents; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Retina | 1980 |
Inhibition by arylsulphatase A of Na-independent [3H]-GABA and [3H]-muscimol binding to bovine cerebellar synaptic membranes.
Topics: Animals; Brain; Cattle; Cerebellum; Cerebroside-Sulfatase; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Sodium; Sulfatases; Synaptic Membranes | 1980 |
Effects of muscimol on the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Membrane Potentials; Muscimol; Neuromuscular Junction; Oxazoles; Synapses | 1981 |
Anion-dependent modulation of [3H]muscimol binding and of GABA-stimulated [3H]flunitrazepam binding by picrotoxin and related CNS convulsants.
Topics: Animals; Anions; Anti-Anxiety Agents; Cerebral Cortex; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Strychnine; Tubocurarine | 1982 |
Relative disposition of the GABA agonists THIP and muscimol in the brain of the rat.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Time Factors | 1982 |
The effect of temperature and chloride ions on the stimulation of [3H]flunitrazepam binding by the muscimol analogues THIP and piperidine-4-sulfonic acid.
Topics: Animals; Anti-Anxiety Agents; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Oxazoles; Piperidines; Rats; Stimulation, Chemical; Temperature; Tritium | 1980 |
[Differences in the mechanism of the antihypoxic action of benzodiazepine receptor agonists and muscimol].
Topics: Animals; Anti-Anxiety Agents; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Hypoxia; Ligands; Mice; Muscimol; Oxazoles; Receptors, GABA-A | 1984 |
Plasma growth hormone and prolactin response to dopaminergic GABAmimetic and cholinergic stimulation in Huntington's disease.
Topics: Adult; Apomorphine; Arecoline; Dopamine; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Male; Muscimol; Oxazoles; Prolactin | 1983 |
Therapeutic failure of GABA agonist treatment in Huntington's disease.
Topics: gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoxazoles; Oxazoles | 1984 |
GABA receptors in bovine cerebral blood vessels: binding studies with [3H]muscimol.
Topics: Animals; Binding, Competitive; Cattle; Cerebral Arteries; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Pia Mater; Receptors, Neurotransmitter; Vasodilation | 1980 |
Effect of the GABA receptor agonist muscimol on regional cerebral blood flow in the rat.
Topics: Animals; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Female; gamma-Aminobutyric Acid; Mesencephalon; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Thalamus | 1980 |
Autoradiographic localization of 3H-GABA and 3H-muscimol binding in rat cerebellar cultures.
Topics: Animals; Autoradiography; Binding Sites; Cerebellum; Culture Techniques; Dendrites; gamma-Aminobutyric Acid; Muscimol; Neurons; Oxazoles; Purkinje Cells; Rats; Receptors, Neurotransmitter | 1980 |
Substrate specificity of [3H]muscimol binding to a particulate fraction of a neuron-enriched culture of embryonic rat brain.
Topics: Animals; Binding, Competitive; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neurons; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
Potentiation by intraventricular muscimol of the anticonflict effect of benzodiazepines.
Topics: Animals; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drinking; Eating; Fear; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter | 1980 |
Na+-independent binding of [3H]GABA and [3H]muscimol to a "microsomal" fraction, but not to a myelin fraction of rat brain; further evidence that glial elements do not possess GABA-receptors.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microscopy, Electron; Microsomes; Muscimol; Neuroglia; Oxazoles; Rats; Receptors, Neurotransmitter; Sodium; Tritium | 1980 |
Inhibitory action of ibotenic acid on the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ibotenic Acid; Membrane Potentials; Neural Inhibition; Neuromuscular Junction; Oxazoles; Picrotoxin; Receptors, Neurotransmitter | 1980 |
Increase in striatal [3H]muscimol binding following intrastriatal injection of kainic acid: a denervation supersensitivity phenomenon.
Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Male; Microinjections; Muscimol; Muscle Denervation; Octoxynol; Oxazoles; Polyethylene Glycols; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
GABA and muscimol inhibit the release of prolactin from dispersed rat anterior pituitary cells.
Topics: Animals; Bicuculline; Dopamine; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
The insensitivity of developing benzodiazepine receptors to chronic treatment with diazepam, GABA and muscimol in brain cell cultures.
Topics: Animals; Brain; Cell Membrane; Cells, Cultured; Diazepam; Female; Fetus; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Oxazoles; Pregnancy; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Localized binding of [3H]muscimol to synapses in chicken retina.
Topics: Animals; Autoradiography; Binding, Competitive; Chickens; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Retina; Synapses | 1981 |
GABA and muscimol open ion channels of different lifetimes on cultured mouse spinal cord cells.
Topics: Animals; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Mice; Muscimol; Neurons; Oxazoles; Spinal Cord | 1981 |
GABAergic synapses in the goldfish retina: an autoradiographic study of 3H-muscimol and 3H-GABA binding.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Goldfish; Muscimol; Neurons; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Muscarinic; Retina; Synapses; Visual Pathways | 1981 |
3H-muscimol binding in synaptosomal fractions from bovine and developing rabbit retinas.
Topics: Animals; Binding, Competitive; Cattle; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission; Synaptosomes | 1981 |
Glutamic acid decarboxylase and gamma-aminobutyric acid in Huntington's disease fibroblasts and other cultured cells, determined by a [3H]muscimol radioreceptor assay.
Topics: Carboxy-Lyases; Cells, Cultured; Fibroblasts; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Huntington Disease; Kinetics; Muscimol; Oxazoles; Radioligand Assay; Receptors, Cell Surface; Receptors, GABA-A; Skin | 1981 |
The binding of the GABA agonist [3H]THIP to rat brain synaptic membranes.
Topics: Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Organ Specificity; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Tritium | 1982 |
Acute and chronic effects of pentobarbital in relation to postsynaptic GABA receptors: a study with muscimol.
Topics: Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Muscimol; Oxazoles; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Sleep; Substance Withdrawal Syndrome; Synaptic Membranes | 1982 |
THIP inhibits feeding behavior in fasted rats.
Topics: Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Eating; Food Deprivation; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Binding of [3H]gamma-aminobutyric acid and [3H]muscimol in purified rat brain synaptic plasma membranes and the effects of bicuculline.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Tritium | 1982 |
Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Mice; Muscimol; Neurons; Oxazoles; Pentobarbital; Spinal Cord | 1982 |
(3H)-muscimol, (3H)-nipecotic acid and (3H)-isoguvacine as autoradiographic markers for GABA neurotransmission.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Goldfish; Guinea Pigs; Isonicotinic Acids; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Oxazoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission | 1982 |
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship | 1982 |
High specific binding of [3H]GABA and [3H]muscimol to membranes from dendrodendritic synaptosomes of the rat olfactory bulb.
Topics: Animals; Dendrites; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Subcellular Fractions; Synaptic Membranes; Synaptosomes | 1982 |
Muscimol and some aza analogues: molecular orbital calculations relating to their potency as GABA mimetics.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Electrons; gamma-Aminobutyric Acid; Humans; Molecular Conformation; Muscimol; Oxazoles; Pyrazoles; Pyrazolones; Receptors, Neurotransmitter; Rotation; Structure-Activity Relationship; Triazoles | 1982 |
Further characterization of the anorexic action of orally-administered THIP, a GABA-analogue, in the rat.
Topics: Administration, Oral; Animals; Bicuculline; Eating; gamma-Aminobutyric Acid; Isoxazoles; Male; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Strychnine | 1982 |
Comparison of centrifugation and filtration assays of ligand binding: do multiple GABA receptive sites exist?
Topics: Animals; Brain; Cattle; Centrifugation; Cerebral Cortex; Filtration; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1982 |
Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography.
Topics: Animals; Autoradiography; Corpus Striatum; gamma-Aminobutyric Acid; Globus Pallidus; Kainic Acid; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Substantia Nigra; Thalamus | 1983 |
4,5,6,7-Tetrahydroisothiazolo[5,4-c]pyridin-3-ol and related analogues of THIP. Synthesis and biological activity.
Topics: Animals; Cats; Cerebral Cortex; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1983 |
Bicuculline insensitive effects of baclofen.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1983 |
[3H]muscimol binding site on purified benzodiazepine receptor.
Topics: Animals; Binding Sites; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Molecular Weight; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Diazepam stimulates the binding of GABA and muscimol but not THIP to rat brain membranes.
Topics: Analgesics; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Decreased high-affinity binding of [3H]muscimol to cerebral synaptic membranes of scrapie-infected mice.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Scrapie; Sheep; Synaptic Membranes | 1984 |
Intranigral muscimol suppresses ethanol withdrawal seizures.
Topics: Acoustic Stimulation; Alcoholism; Animals; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Substantia Nigra | 1984 |
Microiontophoretically applied THIP effects upon nociceptive responses of neurons in medial thalamus.
Topics: Animals; Evoked Potentials; gamma-Aminobutyric Acid; Isoxazoles; Male; Morphine; Neurons; Nociceptors; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinothalamic Tracts; Synaptic Transmission; Tail; Thalamic Nuclei | 1983 |
In vivo release of [3H]GABA in cat caudate nucleus and substantia nigra. II. Involvement of different thalamic nuclei in the bilateral changes induced by a nigral application of muscimol.
Topics: Animals; Cats; Caudate Nucleus; Dominance, Cerebral; Female; gamma-Aminobutyric Acid; Male; Muscimol; Neural Pathways; Neurons; Oxazoles; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei | 1984 |
Methylphenidate, apomorphine, THIP, and diazepam in monkeys: dopamine-GABA behavior related to psychoses and tardive dyskinesia.
Topics: Animals; Apomorphine; Chlorocebus aethiops; Diazepam; Dopamine; Drug Interactions; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Hallucinations; Humans; Isoxazoles; Male; Methylphenidate; Motor Activity; Oxazoles; Psychoses, Substance-Induced | 1984 |
[Influence of the GABAergic system on eating behavior induced by the tail pinching technic in rats].
Topics: Animals; Energy Intake; Feeding Behavior; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Rats, Inbred Strains; Stress, Psychological; Valproic Acid | 1981 |
Ibotenate-induced neuronal degeneration in immature rat brain.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Catecholamines; Cerebellum; Corpus Striatum; Female; gamma-Aminobutyric Acid; Hippocampus; Ibotenic Acid; Male; Oxazoles; Rats; Rats, Inbred Strains | 1984 |
Autoradiographic studies of [3H]-glycine, [3H]-GABA, and [3H]-muscimol uptake in the mudpuppy retina.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Microscopy, Electron; Muscimol; Necturus; Oxazoles; Retina; Tritium | 1984 |
Synergistic anticonvulsant effects of a GABA agonist and glycine.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Male; Mice; Muscimol; Oxazoles; Seizures | 1984 |
Feeding induced by injections of muscimol into the substantia nigra of rats: unaffected by haloperidol but abolished by large lesions of the superior colliculus.
Topics: Animals; Brain Mapping; Corpus Striatum; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Substantia Nigra; Superior Colliculi | 1984 |
GABAergic agents in the medial septal nucleus affect hippocampal theta rhythm and acetylcholine utilization.
Topics: Acetylcholine; Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Rats, Inbred Strains; Septal Nuclei; Theta Rhythm | 1984 |
GABA agonists inhibit the vasopressin-dependent pressor effects of central angiotensin II.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Brain; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1984 |
In vivo release of [3H]GABA in cat caudate nucleus and substantia nigra. I. Bilateral changes induced by a unilateral nigral application of muscimol.
Topics: Animals; Brain Mapping; Cats; Caudate Nucleus; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Substantia Nigra | 1983 |
Neuronal subpopulations in cat retina which accumulate the GABA agonist, (3H)muscimol: a combined Golgi and autoradiographic study.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Oxazoles; Retina | 1983 |
Unilateral injection of GABA agonists in the superior colliculus: asymmetry to tactile stimulation.
Topics: Analgesics; Animals; Baclofen; Functional Laterality; gamma-Aminobutyric Acid; Isoxazoles; Motor Activity; Muscimol; Oxazoles; Physical Stimulation; Rats; Rats, Inbred Strains; Superior Colliculi; Touch | 1983 |
Effects of nigral application of muscimol on release of [3H] gamma-aminobutyrate and on multiunit activity in various cat thalamic nuclei.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Substantia Nigra; Thalamic Nuclei; Tritium | 1983 |
GABA-mediated inhibition of breathing in the late gestation sheep fetus.
Topics: Animals; Apnea; Female; Fetal Hypoxia; Fetus; gamma-Aminobutyric Acid; Gestational Age; Muscimol; Oxazoles; Picrotoxin; Pregnancy; Respiration; Sheep | 1983 |
Induction of mouse-killing in the rat by intraventricular injection of a GABA-agonist.
Topics: Aggression; Animals; Arousal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Injections, Intraventricular; Isoxazoles; Male; Motor Activity; Oxazoles; Rats; Rats, Inbred Strains; Reaction Time | 1983 |
Evidence that the nigrotegmental GABAergic projection mediates stereotypy induced by apomorphine and intranigral muscimol.
Topics: Animals; Apomorphine; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Neural Pathways; Oxazoles; Pons; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Tegmentum Mesencephali | 1983 |
Extrastriatal circuits activated by intrastriatal muscimol: a [14C]2-deoxyglucose investigation.
Topics: Animals; Brain; Brain Mapping; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Rats, Inbred Strains | 1984 |
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate | 1984 |
Nigral muscimol infusions facilitate the development of seizures in immature rats.
Topics: Age Factors; Animals; Flurothyl; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Seizures; Substantia Nigra | 1984 |
Muscimol-scopolamine interactions in the rat brain: a study with 2-deoxy-D-[1-14C]glucose.
Topics: Animals; Brain; Deoxyglucose; gamma-Aminobutyric Acid; Glucose; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Scopolamine | 1984 |
Effects of the bicyclic GABA agonist, THIP, on myoclonic and seizure responses in mice and baboons with reflex epilepsy.
Topics: Animals; Anticonvulsants; Electroencephalography; gamma-Aminobutyric Acid; Haplorhini; Isoxazoles; Mice; Mice, Inbred DBA; Myoclonus; Oxazoles; Papio; Photic Stimulation; Seizures; Time Factors | 1980 |
Circling behavior induced by intranigral injections of GABA and muscimol in rats.
Topics: Animals; Atropine; Behavior; Bicuculline; Brain Chemistry; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Injections; Muscimol; Oxazoles; Rats; Stereotyped Behavior; Strychnine; Substantia Nigra; Time Factors | 1980 |
Sodium di-n-propylacetate (valproate) potentiates responses to GABA and muscimol on single central neurones.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Medulla Oblongata; Muscimol; Neurons; Oxazoles; Rats; Reticular Formation; Valproic Acid | 1980 |
Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Humans; Male; Mice; Motor Activity; Muscimol; Nipecotic Acids; Oxazoles; Social Isolation; Time Factors; Valproic Acid | 1980 |
Modulatory interactions between norepinephrine and taurine, beta-alanine, gamma-aminobutyric acid and muscimol, applied iontophoretically to cerebellar Purkinje cells.
Topics: Alanine; Animals; beta-Alanine; Cerebellum; Female; gamma-Aminobutyric Acid; Iontophoresis; Muscimol; Nerve Endings; Norepinephrine; Oxazoles; Purkinje Cells; Rats; Taurine | 1981 |
[Protective effects of muscimol on acute brain ischemia in the rat (author's transl)].
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Baclofen blocks postsynaptic inhibition but not the effect of muscimol in the olfactory cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Neural Conduction; Neural Inhibition; Olfactory Pathways; Oxazoles; Synapses | 1983 |
Quantitative determination of the gamma-aminobutyric acid agonist, 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol, in serum by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dogs; gamma-Aminobutyric Acid; Humans; Isoxazoles; Kinetics; Oxazoles; Papio; Rats; Spectrophotometry, Ultraviolet | 1983 |
Effects of barbiturates and ethanol on muscimol-induced release of [3H]-D-aspartate from rodent cerebellum.
Topics: Animals; Aspartic Acid; Cerebellum; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Oxazoles; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Tritium | 1983 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
Effects of the putative GABAergic agonists, muscimol and THIP, upon local cerebral glucose utilisation.
Topics: Analgesics; Animals; Brain; Deoxy Sugars; Deoxyglucose; gamma-Aminobutyric Acid; Glycolysis; Isoxazoles; Male; Muscimol; Organ Specificity; Oxazoles; Rats; Rats, Inbred Strains | 1982 |
Effects of gamma-aminobutyric acid agonist and antagonist drugs on local cerebral glucose utilization.
Topics: Animals; Autoradiography; Bicuculline; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; gamma-Aminobutyric Acid; Glycolysis; Male; Muscimol; Organ Specificity; Oxazoles; Rats | 1982 |
Differential localization of radioactive gamma-aminobutyric acid and muscimol in isolated and in vivo mouse retina.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Muscimol; Neuroglia; Oxazoles; Retina; Time Factors; Tissue Distribution | 1982 |
Comparison of the antinociceptive actions of THIP and morphine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoxazoles; Male; Mice; Mice, Inbred Strains; Morphine; Oxazoles; Reaction Time; Species Specificity | 1982 |
Antinociceptive and anticonvulsive effect of THIP, a pure GABA agonist.
Topics: Analgesics; Animals; Anticonvulsants; Benzoquinones; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Mice; Morphine; Oxazoles; Quinones; Rats; Rats, Inbred Strains; Reaction Time | 1982 |
An in vivo method for testing GABAergic compounds.
Topics: Animals; Apomorphine; gamma-Aminobutyric Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Oxazoles; Picrotoxin | 1982 |
Increases and decreases in local cerebral glucose utilization in response to GABA agonists.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Glucose; Isoxazoles; Male; Muscimol; Oxazoles; Rats | 1981 |
GABA and muscimol binding processes in CNS tissue culture preparations.
Topics: Animals; Astrocytes; Brain; Culture Media; Culture Techniques; gamma-Aminobutyric Acid; Mice; Muscimol; Neurons; Oxazoles; Rats | 1981 |
Autoradiographic localization of [3H]muscimol in the cat retina.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Neurons; Oxazoles; Retina; Tritium | 1981 |
Differential effects of sodium-free media on gamma-aminobutyrate and muscimol-evoked conductance increases recorded from lobster muscle fibres.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; Evoked Potentials; gamma-Aminobutyric Acid; Kinetics; Lithium; Muscimol; Muscles; Nephropidae; Nipecotic Acids; Oxazoles; Sodium | 1981 |
Paradoxical blockade of a muscimol response by THIP, a GABA agonist and also by GABA-transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; Myoclonus; Oxazoles; Time Factors; Transaminases | 1981 |
Single unit responses of substantia nigra and globus pallidus neurons to GABA agonist and antagonist drugs.
Topics: Animals; gamma-Aminobutyric Acid; Globus Pallidus; Iontophoresis; Isoxazoles; Kainic Acid; Male; Muscimol; Neurons; Oxazoles; Rats; Rats, Inbred Strains; Substantia Nigra | 1981 |
Decrease in effects of muscimol on the dorsal root after repeated administration of diazepam in rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Spinal Nerve Roots; Time Factors | 1981 |
Lack of Na"-independent binding of [3H]GABA or [3H]muscimol to particulate fractions of cultured astroblasts.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Radioligand Assay; Rats; Sodium; Tritium | 1980 |
Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1980 |
Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.
Topics: Animals; Binding, Competitive; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Ligands; Mice; Muscimol; Neurons; Oxazoles; Protein Binding; Receptors, Drug; Tritium | 1980 |
In vivo release of endogenous gamma-aminobutyric acid from rat striatum: effects of muscimol, oxotremorine, and morphine.
Topics: Animals; Corpus Striatum; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Muscimol; Nalorphine; Oxazoles; Oxotremorine; Potassium; Rats; Tetrodotoxin | 1980 |
Binding of muscimol and GABA in sub-fractions of a crude membrane fraction of rat brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Oxazoles; Rats; Synaptic Membranes | 1980 |
GABAergic actions of THIP in vivo and vitro: a comparison with muscimol and GABA.
Topics: Animals; Binding Sites; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Oxazoles; Rats; Substantia Nigra | 1980 |
Anorexic effects of ethanolamine-O-sulfate and muscimol in the rat: evidence that GABA inhibits ingestive behavior.
Topics: 4-Aminobutyrate Transaminase; Animals; Appetite Depressants; Body Weight; Brain Chemistry; Dextroamphetamine; Ethanolamines; Feeding Behavior; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Oxazoles; Rats | 1980 |
Some characteristics of [3H]muscimol binding to synaptic membrane from rat brain.
Topics: Animals; Binding Sites; Brain; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Muscimol; Oxazoles; Polyethylene Glycols; Rats; Synaptic Membranes; Temperature | 1980 |
Decreases in the binding of [3H]GABA and [3H]muscimol to a particulate fraction of rat brain produced by human sera; some speculations.
Topics: Animals; Blood Physiological Phenomena; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Nerve Tissue Proteins; Oxazoles; Protein Binding; Rats; Synaptic Membranes | 1980 |
[3H]Muscimol binding in the rat retina.
Topics: Animals; Binding Sites; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membranes; Muscimol; Octoxynol; Oxazoles; Polyethylene Glycols; Rats; Retina | 1980 |
Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat.
Topics: Anesthesia; Animals; Dopamine; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Injections, Intraventricular; Male; Muscimol; Oxazoles; Parasympathetic Nervous System; Rats; Serotonin; Sympathetic Nervous System | 1980 |
Na+-independent binding of [3H]GABA and [3H]muscimol to subcellular particles of neural primary cultures and whole brain.
Topics: Animals; Animals, Newborn; Astrocytes; Binding Sites; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Sodium | 1980 |
Measurement of gamma-aminobutyric acid in human cerebrospinal fluid: radioreceptor assay using [3H]muscimol.
Topics: Animals; Cattle; gamma-Aminobutyric Acid; Humans; Muscimol; Oxazoles; Radioligand Assay; Tritium | 1981 |
Ca(2+)-induced rebound potentiation of gamma-aminobutyric acid-mediated currents requires activation of Ca2+/calmodulin-dependent kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cerebellum; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Kinetics; Marine Toxins; Membrane Potentials; Nerve Fibers; Oxazoles; Purkinje Cells; Rats; Receptors, GABA-A; Signal Transduction; Staurosporine | 1996 |
Functional significance of cannabinoid-mediated, depolarization-induced suppression of inhibition (DSI) in the hippocampus.
Topics: Action Potentials; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Cannabinoids; Colforsin; Electric Stimulation; Enzyme Activators; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lidocaine; Male; Marine Toxins; Morpholines; Naphthalenes; Neural Inhibition; omega-Conotoxin GVIA; Oxazoles; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, GABA-A; Sodium Channel Blockers | 2003 |
Modulation by brain natriuretic peptide of GABA receptors on rat retinal ON-type bipolar cells.
Topics: Animals; Atrial Natriuretic Factor; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Calmodulin; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guanylate Cyclase; Heparin; Imidazoles; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Male; Membrane Potentials; Natriuretic Peptide, Brain; Oxazoles; Patch-Clamp Techniques; Peptide Fragments; Peptides, Cyclic; Polysaccharides; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Receptors, Cytoplasmic and Nuclear; Receptors, GABA; Receptors, GABA-A; Retinal Bipolar Cells; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin | 2006 |
Characterization of spontaneous inhibitory postsynaptic currents in cultured rat retinal amacrine cells.
Topics: Amacrine Cells; Animals; Bicuculline; Boron Compounds; Cadmium Chloride; Calcium; Calcium Channel Blockers; Cells, Cultured; Dantrolene; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Imidazoles; Inhibitory Postsynaptic Potentials; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Membrane Potentials; Oxazoles; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2010 |
Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABA
Topics: Benzodiazepines; Binding, Competitive; Computer Simulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Molecular Docking Simulation; Oxazoles; Protein Conformation; Protein Subunits; Receptors, GABA-A; Structure-Activity Relationship | 2017 |
Selective inhibition of extra-synaptic α5-GABA
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain; Female; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Long-Term Potentiation; Male; Memory; Mice, Inbred C57BL; Muscimol; Neural Inhibition; Nootropic Agents; Oxazoles; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Culture Techniques | 2017 |
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Chlorocebus aethiops; Cognition; COS Cells; Dentate Gyrus; Depression; Entorhinal Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hyperalgesia; Locus Coeruleus; Long-Term Potentiation; Male; Memory Disorders; Mice, Inbred C57BL; Neuralgia; Norepinephrine; Oxazoles; Receptors, Adrenergic, alpha-2; Receptors, Histamine H3; Structural Homology, Protein | 2021 |