Page last updated: 2024-08-21

oxazoles and fosbretabulin

oxazoles has been researched along with fosbretabulin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biersack, B; Effenberger, K; Ocker, M; Schobert, R1
Biersack, B; Dietrich, A; Effenberger, K; Knauer, S; Mueller, T; Schobert, R1
Chen, K; Hu, Y; Li, QS; Lu, X; Yan, R; Zhu, HL1
Han, F; Li, J; Liu, M; Qi, X; Wang, P; Zhang, Q; Zhang, W1

Other Studies

4 other study(ies) available for oxazoles and fosbretabulin

ArticleYear
Oxazole-bridged combretastatin A analogues with improved anticancer properties.
    ChemMedChem, 2010, Mar-01, Volume: 5, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Combretum; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Neoplastic; HCT116 Cells; HL-60 Cells; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Oxazoles; Reactive Oxygen Species; Stilbenes; Tumor Suppressor Protein p53

2010
4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles that are cytotoxic against combretastatin A resistant tumor cells and vascular disrupting in a cisplatin resistant germ cell tumor model.
    Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Chick Embryo; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazoles; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Germ Cell and Embryonal; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxazoles; Stilbenes; Structure-Activity Relationship; Testicular Neoplasms; Transplantation, Heterologous; Tubulin Modulators

2010
Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
    Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2

    Topics: Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Drug Design; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Naphthalenes; Oxadiazoles; Oxazoles; Protein Binding; Protein Structure, Tertiary; Stilbenes; Tubulin; Tubulin Modulators

2012
CA-1H, a novel oxazole bearing analogue of combretastatin A-4, disrupts the tumor vasculatures and inhibits the tumor growth via inhibiting tubulin polymerization.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 80

    Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cytoskeleton; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Necrosis; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxazoles; Polymerization; Stilbenes; Tubulin; Xenograft Model Antitumor Assays

2016
chemdatabank.com