Page last updated: 2024-08-21

oxazoles and flutamide

oxazoles has been researched along with flutamide in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.71)18.2507
2000's16 (57.14)29.6817
2010's8 (28.57)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Kelce, WR; Sar, M; Wilson, EM; Wong, C1
Gray, LE; Kelce, WR; Lambright, CR; Roberts, KP1
Sohoni, P; Sumpter, JP1
Holst, M; Ritzén, EM; Svechnikov, K1
Dalgaard, M; Hossaini, A; Larsen, JJ; Nellemann, C; Vinggaard, AM1
Baatrup, E; Bayley, M; Junge, M1
Frame, SR; Ladics, GS; O'Connor, JC1
Gray, LE; Hotchkiss, AK; Ostby, JS; Vandenbergh, JG1
Ishimura, R; Kawakami, T; Kubota, K; Kurosawa, S; Ohsako, S; Qing, W; Sakaue, M; Takeda, K; Tohyama, C1
Choi, KS; Dong, MS; Han, SY; Kang, IH; Kil, KS; Kim, HS; Kim, IY; Kim, TS; Moon, HJ; Park, YI; Shin, JH1
Ahn, B; Do, JC; Hong, JT; Kim, YC; Lee, BJ; Lee, YS; Nam, SY; Yu, WJ; Yun, YW1
Derk, RC; Murono, EP1
Kishimoto, A; Kizu, R; Nagaosa, K; Nakagawa, A; Nakanishi, Y; Shiratsuchi, A1
Akgul, Y; Derk, RC; Meighan, T; Murono, EP; Rao, KM1
Axelstad, M; Christiansen, S; Dalgaard, M; Hass, U; Kortenkamp, A; Metzdorff, SB; Scholze, M; Vinggaard, AM1
Axelstad, M; Boberg, J; Christiansen, S; Hass, U; Kortenkamp, A; Scholze, M1
Bláha, L; Haeba, MH; Hilscherová, K; Mazurová, E1
Anway, MD; Rekow, SS; Skinner, MK1
Abe, J; Doi, Y; Inawaka, K; Kawabe, M; Kawamura, S; Shirai, T; Takahashi, S; Tarui, H; Tomigahara, Y1
Andersen, HR; Kjaerstad, MB; Nellemann, C; Taxvig, C1
Ankley, GT; Bencic, DC; Lazorchak, J; Martinović-Weigelt, D; Villeneuve, DL; Wang, RL1
Kolle, SN; Krennrich, G; Landsiedel, R; Melching-Kollmuss, S; van Ravenzwaay, B1
Anway, MD; Covert, TR; Guerrero-Bosagna, C; Haque, MM; Nilsson, EE; Settles, M; Skinner, MK1
Iguchi, T; Nakamura, A; Takanobu, H; Tamura, I; Tatarazako, N; Yamamuro, M1
Cao, S; Lou, QQ; Qin, ZF; Wei, WJ; Xu, W; Zhang, YF; Zhao, YX1
Alavi, SM; Golshan, M; Habibi, HR1
Buesen, R; Fussell, KC; Gröters, S; Jiang, X; Melching-Kollmuss, S; Schneider, S; Strauss, V; van Ravenzwaay, B1
Lorenzetti, S; Mantovani, A; Marcoccia, D; Smeriglio, A; Trombetta, D1

Other Studies

28 other study(ies) available for oxazoles and flutamide

ArticleYear
Androgen receptor antagonist versus agonist activities of the fungicide vinclozolin relative to hydroxyflutamide.
    The Journal of biological chemistry, 1995, Aug-25, Volume: 270, Issue:34

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Binding, Competitive; Cell Line; Dihydrotestosterone; DNA; Flutamide; Fungicides, Industrial; Humans; Kinetics; Male; Oxazoles; Receptors, Androgen; Recombinant Proteins; Reproduction; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1995
Vinclozolin and p,p'-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Androgen Antagonists; Androgen-Binding Protein; Animals; Clusterin; Dichlorodiphenyl Dichloroethylene; Drug Implants; Flutamide; Gene Expression Regulation; Glycoproteins; Male; Molecular Chaperones; Orchiectomy; Organ Size; Oxazoles; Prostate; Prostatein; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Secretoglobins; Seminal Vesicles; Testosterone; Uteroglobin

1997
Several environmental oestrogens are also anti-androgens.
    The Journal of endocrinology, 1998, Volume: 158, Issue:3

    Topics: Androgen Antagonists; Androgens; Benzhydryl Compounds; Biological Assay; DDT; Dichlorodiphenyl Dichloroethylene; Diethylstilbestrol; Environmental Pollution; Estrogen Antagonists; Estrogens; Flutamide; Fungicides, Industrial; Gene Expression; Hormones; Humans; Oxazoles; Pesticides; Phenols; Receptors, Androgen; Receptors, Estrogen; Saccharomyces cerevisiae; Xenobiotics

1998
Androgen and estrogen stimulation of ornithine decarboxylase activity in mouse kidney.
    The Journal of steroid biochemistry and molecular biology, 2000, Dec-31, Volume: 75, Issue:4-5

    Topics: Androgen Antagonists; Animals; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Estradiol; Female; Flutamide; Kidney; Mice; Mice, Inbred CBA; Ornithine Decarboxylase; Oxazoles; Spironolactone; Testosterone

2000
Quantification of antiandrogen effect determined by Lightcycler technology.
    Toxicology, 2001, May-28, Volume: 163, Issue:1

    Topics: Androgen Antagonists; Androgen-Binding Protein; Animals; Clusterin; Flutamide; Fungicides, Industrial; Gene Expression; Glycoproteins; Luteinizing Hormone; Male; Molecular Chaperones; Organ Size; Oxazoles; Prostate; Prostatein; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Secretoglobins; Testosterone; Toxicity Tests; Uteroglobin

2001
Exposure of juvenile guppies to three antiandrogens causes demasculinization and a reduced sperm count in adult males.
    Aquatic toxicology (Amsterdam, Netherlands), 2002, Volume: 56, Issue:4

    Topics: Androgen Antagonists; Animals; Dichlorodiphenyl Dichloroethylene; Female; Flutamide; Fungicides, Industrial; Insecticides; Male; Oxazoles; Poecilia; Reproduction; Sex Characteristics; Sex Ratio; Sexual Behavior, Animal; Sexual Maturation; Sperm Count; Spermatogenesis

2002
Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 69, Issue:1

    Topics: Androgen Antagonists; Androgens; Animals; Body Weight; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Diethylhexyl Phthalate; Drug Evaluation, Preclinical; Flutamide; Immune System; Linuron; Male; Organ Size; Oxazoles; Rats; Rats, Sprague-Dawley; Thyroid Gland

2002
An environmental antiandrogen, vinclozolin, alters the organization of play behavior.
    Physiology & behavior, 2003, Volume: 79, Issue:2

    Topics: Aging; Androgen Antagonists; Animals; Animals, Newborn; Behavior, Animal; Female; Flutamide; Fungicides, Industrial; Interpersonal Relations; Male; Oxazoles; Play and Playthings; Rats; Rats, Sprague-Dawley

2003
Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat.
    The Journal of reproduction and development, 2003, Volume: 49, Issue:5

    Topics: Androgen Antagonists; Animals; Cholesterol Side-Chain Cleavage Enzyme; Flutamide; Fungicides, Industrial; Gene Expression; Hormones; Luteinizing Hormone, beta Subunit; Male; Oxazoles; Pituitary Gland; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Spermatogenesis; Steroids; Testis; Testosterone

2003
Comparison of anti-androgenic activity of flutamide, vinclozolin, procymidone, linuron, and p, p'-DDE in rodent 10-day Hershberger assay.
    Toxicology, 2004, Jul-01, Volume: 199, Issue:2-3

    Topics: Administration, Oral; Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Interactions; Flutamide; Genitalia, Male; Injections, Subcutaneous; Linuron; Luteinizing Hormone; Male; Orchiectomy; Organ Size; Oxazoles; Rats; Rats, Sprague-Dawley; Testosterone

2004
Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.
    The Journal of veterinary medical science, 2004, Volume: 66, Issue:7

    Topics: Administration, Oral; Androgen Antagonists; Animals; Flutamide; Fungicides, Industrial; Male; Methyltestosterone; Oxazoles; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sperm Count; Sperm Motility; Spermatozoa; Testis; Testosterone

2004
The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats.
    Reproductive toxicology (Elmsford, N.Y.), 2004, Volume: 19, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Combinations; Estrogen Antagonists; Flutamide; Insecticides; Leydig Cells; Male; Methoxychlor; Oxazoles; Phenols; Rats; Rats, Sprague-Dawley; Testosterone

2004
Perturbation of spermatogenesis by androgen antagonists directly injected into seminiferous tubules of live mice.
    Reproduction (Cambridge, England), 2007, Volume: 133, Issue:1

    Topics: Androgen Antagonists; Animals; Antineoplastic Agents; Blood-Testis Barrier; Busulfan; Flutamide; Male; Mice; Microinjections; Oxazoles; Seminiferous Tubules; Spermatogenesis; Toxicity Tests

2007
The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.
    Reproductive toxicology (Elmsford, N.Y.), 2008, Volume: 25, Issue:1

    Topics: Androgen Antagonists; Animals; Benzhydryl Compounds; Catalytic Domain; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Fulvestrant; Gene Expression Regulation, Enzymologic; Gonadotropins, Equine; Methoxychlor; Ovary; Oxazoles; Phenols; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger

2008
Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat.
    Environmental health perspectives, 2007, Volume: 115 Suppl 1

    Topics: Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Drug Synergism; Female; Flutamide; Forecasting; Genitalia, Male; Male; Nipples; Oxazoles; Pregnancy; Rats; Rats, Wistar; Sex Differentiation

2007
Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat.
    International journal of andrology, 2008, Volume: 31, Issue:2

    Topics: Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Flutamide; Hypospadias; Male; Oxazoles; Rats; Rats, Wistar

2008
Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna.
    Environmental science and pollution research international, 2008, Volume: 15, Issue:3

    Topics: Animals; Animals, Newborn; Daphnia; Dicofol; Endocrine Disruptors; Female; Flutamide; Ketoconazole; Locomotion; Male; Molting; Oxazoles; Reproduction; Sex Ratio; Sexual Maturation; Water Pollutants, Chemical

2008
Comparative anti-androgenic actions of vinclozolin and flutamide on transgenerational adult onset disease and spermatogenesis.
    Reproductive toxicology (Elmsford, N.Y.), 2008, Volume: 26, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Dose-Response Relationship, Drug; Female; Flutamide; Male; Oxazoles; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sperm Count; Sperm Motility; Spermatogenesis; Spermatozoa; Testis

2008
Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male rats of subsequent generations.
    Toxicology and applied pharmacology, 2009, Jun-01, Volume: 237, Issue:2

    Topics: Androgen Antagonists; Animals; Base Sequence; Bridged Bicyclo Compounds; DNA Methylation; Female; Flutamide; Fungicides, Industrial; Lysophospholipase; Male; Oxazoles; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Spermatogenesis; Spermatozoa; Testis

2009
Mixture effects of endocrine disrupting compounds in vitro.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Drug Combinations; Endocrine Disruptors; Estradiol; Flutamide; Fungicides, Industrial; Genes, Reporter; Humans; Oxazoles; Parabens; Receptors, Androgen; Testosterone; Triazoles

2010
Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads.
    Aquatic toxicology (Amsterdam, Netherlands), 2011, Jan-25, Volume: 101, Issue:2

    Topics: Androgen Receptor Antagonists; Animals; Female; Fertilization; Flutamide; Gene Expression; Gene Expression Profiling; Male; Oligonucleotide Array Sequence Analysis; Ovary; Oxazoles; Receptors, Androgen; Reproduction; Signal Transduction; Spermatogenesis; Steroids; Testis; Water Pollutants, Chemical; Zebrafish

2011
Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.
    Regulatory toxicology and pharmacology : RTP, 2011, Volume: 60, Issue:3

    Topics: Androgen Antagonists; Biological Assay; Drug Synergism; Flutamide; Humans; Oxazoles; Receptors, Androgen; Recombinant Proteins; Risk Assessment; Saccharomyces cerevisiae

2011
Epigenetic transgenerational inheritance of vinclozolin induced mouse adult onset disease and associated sperm epigenome biomarkers.
    Reproductive toxicology (Elmsford, N.Y.), 2012, Volume: 34, Issue:4

    Topics: Androgen Antagonists; Animals; Animals, Outbred Strains; Apoptosis; Biomarkers; DNA Methylation; Endocrine Disruptors; Epigenesis, Genetic; Epigenomics; Female; Flutamide; Kidney; Male; Mice; Mice, Inbred Strains; Ovarian Cysts; Oxazoles; Pregnancy; Prostate; Sperm Motility; Testis

2012
Verification of responses of Japanese medaka (Oryzias latipes) to anti-androgens, vinclozolin and flutamide, in short-term assays.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:5

    Topics: Androgen Antagonists; Animals; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Fertility; Flutamide; Gonads; Liver; Male; Oryzias; Oxazoles; Reproducibility of Results; Sex Characteristics; Time Factors; Toxicity Tests; Vitellogenins

2014
Environmental (anti-)androgenic chemicals affect germinal vesicle breakdown (GVBD) of Xenopus laevis oocytes in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:3

    Topics: Androgen Antagonists; Androgens; Animals; Endocrine Disruptors; Flutamide; Methoxychlor; Nandrolone; Oocytes; Oxazoles; Receptors, Androgen; Testosterone; Trenbolone Acetate; Xenopus laevis

2014
Transcripts of genes encoding reproductive neuroendocrine hormones and androgen receptor in the brain and testis of goldfish exposed to vinclozolin, flutamide, testosterone, and their combinations.
    Fish physiology and biochemistry, 2016, Volume: 42, Issue:4

    Topics: Androgen Antagonists; Androgens; Animals; Brain; Drug Interactions; Fish Proteins; Flutamide; Fungicides, Industrial; Goldfish; Gonadotropin-Releasing Hormone; Kisspeptins; Male; Oxazoles; Pyrrolidonecarboxylic Acid; Receptors, Androgen; Receptors, G-Protein-Coupled; Receptors, LH; Reproduction; RNA, Messenger; Testis; Testosterone

2016
Investigations on the dose-response relationship of combined exposure to low doses of three anti-androgens in Wistar rats.
    Archives of toxicology, 2017, Volume: 91, Issue:12

    Topics: Animals; Dose-Response Relationship, Drug; Estrous Cycle; Female; Flutamide; Imidazoles; Male; Nipples; No-Observed-Adverse-Effect Level; Nonsteroidal Anti-Androgens; Oxazoles; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Spermatozoa; Testosterone

2017
Intracellular distribution of vinclozolin and its metabolites differently affects 5α-dihydrotestosterone (DHT)-induced PSA secretion in LNCaP cells.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 111

    Topics: Androgen Antagonists; Androgens; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Male; Oxazoles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen

2022