Page last updated: 2024-08-21

oxazoles and erb 041

oxazoles has been researched along with erb 041 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (43.48)29.6817
2010's12 (52.17)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Albert, LM; Frail, DE; Harris, HA; Henderson, RA; Keith, JC; Kharode, YP; Komm, BS; Leathurby, Y; Malamas, MS; Marzolf, J; Mewshaw, RE; Miller, CP; Winneker, RC; Zhu, Y1
Bruner-Tran, KL; Harris, HA; Lyttle, CR; Osteen, KG; Zhang, X1
Gustafsson, JA; Haldosén, LA; Helguero, LA; Koehler, KF; Warner, M1
Chelsky, D; Dorner, AJ; Follettie, MT; Harris, HA; Hayward, C; Kearney, P; Keith, JC; Paramithiotis, E; Pinard, M; Thibault, P; Wang, L1
Crabtree, JS; Harris, HA; Peano, BJ; Winneker, RC; Zhang, X; Zhang, Z1
Brandt, MR; Cummons, TA; Harris, HA; Leventhal, L; Piesla, MJ; Rogers, KE1
Rotella, D1
Cvoro, A; Harris, HA; Leitman, DC; Tatomer, D; Tee, MK; Zogovic, T1
Belvisi, MG; Birrell, MA; Catley, MC; de Alba, J; Farrow, S; Haj-Yahia, S; Hardaker, EL1
Hui-hua, D; Shi-long, F; Su-ping, H; Wen-jun, C; Xiu-li, W1
Chang, EC; Charn, TH; Katzenellenbogen, BS; Katzenellenbogen, JA; Lee, YK; Liu, ET1
Christaki, E; Harris, HA; Keith, JC; Kessinian, N; Lavallie, E; Malamas, MS; Mewshaw, RE; Mounts, W; Opal, SM; Palardy, JE; Parejo, NA; Racie, L; Vlasuk, GP1
Castañeda, S; Cutolo, M; Herrero-Beaumont, G; Roman-Blas, JA1
Blackman, BE; Cohen, I; Harris, HA; Leitman, DC; Mellon, SH; Pan, X; Pera, RA; Schonemann, MD; Tagliaferri, M; Weiner, RI; Zhang, L; Zogovic-Kapsalis, T1
Cutolo, M1
Afaq, F; Arumugam, A; Athar, M; Chaudhary, SC; Elmets, CA; Kopelovich, L; Singh, T; Srivastava, RK; Talwelkar, SS; Weng, Z1
Gonzalez, FJ; Peters, JM; Yao, PL1
Emons, G; Girgert, R; Gründker, C; Hinsche, O1
Burnstock, G; Fan, J; Jiang, Q; Li, WX; Ma, B; Sun, JR; Yang, H; Yu, LH; Zhu, TT1
Moehle, C; Ortmann, O; Schüler-Toprak, S; Skrzypczak, M; Treeck, O1
Crider, A; Davis, T; Fagan, K; Kamalasanan, S; Luo, M; Nelson, T; Pillai, A; Terry, AV; Vaibhav, K1
Groothuis, PG; Guo, SW1
Dash, P; Ehrnström, R; Fred Mehrabi, S; Lydrup, ML; Olsson, R; Satapathy, SR; Sjölander, A; Topi, G1

Reviews

2 review(s) available for oxazoles and erb 041

ArticleYear
Reflections on the discovery and significance of estrogen receptor beta.
    Endocrine reviews, 2005, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Ligands; Male; Mice; Models, Molecular; Oxazoles; Prostate; Uterus

2005
Is it time for a paradigm shift in drug research and development in endometriosis/adenomyosis?
    Human reproduction update, 2018, 09-01, Volume: 24, Issue:5

    Topics: Adenomyosis; Clinical Trials as Topic; Drug Development; Endometriosis; Female; Hormone Antagonists; Humans; Infliximab; Oxazoles; Progesterone; Raloxifene Hydrochloride; Treatment Outcome

2018

Trials

2 trial(s) available for oxazoles and erb 041

ArticleYear
Efficacy and safety of a selective estrogen receptor β agonist, ERB-041, in patients with rheumatoid arthritis: a 12-week, randomized, placebo-controlled, phase II study.
    Arthritis care & research, 2010, Volume: 62, Issue:11

    Topics: Adult; Aged; Arthritis, Rheumatoid; Double-Blind Method; Estrogen Receptor beta; Female; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Oxazoles; Treatment Outcome

2010
Selective estrogen receptor agonism lacks clinical benefit in rheumatoid arthritis: comment on the article by van Vollenhoven et al.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:12

    Topics: Arthritis, Rheumatoid; Estrogen Receptor beta; Humans; Oxazoles; Severity of Illness Index; Treatment Outcome

2010

Other Studies

19 other study(ies) available for oxazoles and erb 041

ArticleYear
Evaluation of an estrogen receptor-beta agonist in animal models of human disease.
    Endocrinology, 2003, Volume: 144, Issue:10

    Topics: Animals; Animals, Genetically Modified; Arthritis, Experimental; beta 2-Microglobulin; Bone Density; Bone Diseases, Metabolic; Cell Line; Disease Models, Animal; Estrogen Receptor beta; Female; HLA-B27 Antigen; Humans; Inflammatory Bowel Diseases; Mammary Glands, Animal; Mice; Ovariectomy; Oxazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Estrogen; Uterus; Weight Gain

2003
A selective estrogen receptor-beta agonist causes lesion regression in an experimentally induced model of endometriosis.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Animals; Biopsy; Disease Models, Animal; Endometriosis; Endometrium; Estrogen Receptor beta; Female; Humans; Mice; Mice, Nude; Middle Aged; Organ Culture Techniques; Ovariectomy; Oxazoles; RNA, Messenger

2005
Organ messenger ribonucleic acid and plasma proteome changes in the adjuvant-induced arthritis model: responses to disease induction and therapy with the estrogen receptor-beta selective agonist ERB-041.
    Endocrinology, 2006, Volume: 147, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Biomarkers; Blood Proteins; Estrogen Receptor beta; Gene Expression Profiling; Liver; Lymph Nodes; Male; Organ Specificity; Oxazoles; Random Allocation; Rats; Rats, Inbred Lew; RNA, Messenger; Spleen

2006
Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone-regulated gene markers.
    The Journal of steroid biochemistry and molecular biology, 2006, Volume: 101, Issue:1

    Topics: Animals; Base Sequence; Benzoxazines; DNA Primers; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation; Genetic Markers; Mammary Glands, Animal; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Models, Animal; Naphthols; Oligonucleotide Array Sequence Analysis; Oxazoles; Phenols; Progesterone; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Thiones; Uterus

2006
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain.
    European journal of pharmacology, 2006, Dec-28, Volume: 553, Issue:1-3

    Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor beta; Fulvestrant; Hot Temperature; Hyperalgesia; Inflammation; Male; Oxazoles; Pain; Rats; Rats, Sprague-Dawley

2006
COMP-structure-based design and development of estrogen receptor modulators.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:11

    Topics: Computer Simulation; Drug Design; Drugs, Investigational; Estrogen Receptor beta; Estrogen Receptor Modulators; Humans; Male; Models, Molecular; Oxazoles; Prostatic Hyperplasia; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship

2006
Selective estrogen receptor-beta agonists repress transcription of proinflammatory genes.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Jan-01, Volume: 180, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cytokines; Down-Regulation; Estrogen Receptor beta; Gene Expression Profiling; Humans; Inflammation; Leukocytes, Mononuclear; Oligonucleotide Array Sequence Analysis; Oxazoles; Selective Estrogen Receptor Modulators; Transcription, Genetic; Tumor Necrosis Factor-alpha

2008
Estrogen receptor beta: expression profile and possible anti-inflammatory role in disease.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 326, Issue:1

    Topics: Animals; Asthma; Cells, Cultured; Estrogen Receptor beta; Gene Expression Profiling; Humans; Inflammation; Inflammation Mediators; Male; Oxazoles; Rats; Rats, Inbred BN; RNA, Messenger

2008
ERB-041, a selective ER beta agonist, inhibits iNOS production in LPS-activated peritoneal macrophages of endometriosis via suppression of NF-kappaB activation.
    Molecular immunology, 2009, Volume: 46, Issue:11-12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Endometriosis; Estrogen Receptor beta; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; NF-kappa B; Nitric Oxide Synthase Type II; Oxazoles; Signal Transduction

2009
Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:1

    Topics: Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Ligands; Oxazoles; Phenols; Pyrazoles; Response Elements; RNA, Small Interfering; Transcription Factors

2010
Estrogen receptor beta agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study.
    The Journal of infectious diseases, 2010, Apr-15, Volume: 201, Issue:8

    Topics: Animals; Disease Models, Animal; Estrogen Receptor beta; Female; Gene Expression Profiling; Male; Mice; Mice, Inbred BALB C; Naphthols; Oxazoles; Pneumonia, Pneumococcal; Sepsis; Transcription, Genetic

2010
Estrogen receptor beta-selective agonists stimulate calcium oscillations in human and mouse embryonic stem cell-derived neurons.
    PloS one, 2010, Jul-27, Volume: 5, Issue:7

    Topics: Animals; Blotting, Western; Calcium; Calcium Signaling; Cell Differentiation; Cell Line; Embryonic Stem Cells; Estrogen Receptor beta; Humans; Immunohistochemistry; Immunoprecipitation; Mice; Neurons; Nifedipine; Nitriles; Oxazoles; Phosphorylation; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction

2010
Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:2

    Topics: Animals; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Estrogen Receptor beta; Female; Humans; Mice; Mice, Hairless; Oxazoles; Skin Neoplasms; Ultraviolet Rays; Wnt Signaling Pathway

2014
Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:2

    Topics: Animals; Carcinogenesis; Female; Humans; Oxazoles; Skin Neoplasms; Wnt Signaling Pathway

2014
Estrogen receptor β selective agonists reduce invasiveness of triple-negative breast cancer cells.
    International journal of oncology, 2015, Volume: 46, Issue:2

    Topics: Cell Movement; Cell Proliferation; Coculture Techniques; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Flavanones; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasm Invasiveness; Oxazoles; Receptors, CXCR4; Triple Negative Breast Neoplasms

2015
Inhibitory effect of estrogen receptor beta on P2X3 receptors during inflammation in rats.
    Purinergic signalling, 2017, Volume: 13, Issue:1

    Topics: Animals; Estrogen Receptor beta; Estrogens; Female; Hyperalgesia; Inflammation; Nitriles; Oxazoles; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X3

2017
Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells.
    BMC cancer, 2017, May-08, Volume: 17, Issue:1

    Topics: Androstane-3,17-diol; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor beta; Estrogens; Female; Flavanones; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Oxazoles; Phenols

2017
Estrogen Receptor β Agonist Attenuates Endoplasmic Reticulum Stress-Induced Changes in Social Behavior and Brain Connectivity in Mice.
    Molecular neurobiology, 2018, Volume: 55, Issue:9

    Topics: Animals; Brain; Endoplasmic Reticulum Stress; Estrogen Receptor beta; Female; Hippocampus; Male; Membrane Proteins; Mice, Inbred C57BL; Nerve Net; Oxazoles; Prefrontal Cortex; Protein Serine-Threonine Kinases; Social Behavior; Tunicamycin; X-Box Binding Protein 1

2018
Tumour-suppressive effect of oestrogen receptor β in colorectal cancer patients, colon cancer cells, and a zebrafish model.
    The Journal of pathology, 2020, Volume: 251, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Estrogen Receptor beta; Female; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Oxazoles; Receptors, Leukotriene; Signal Transduction; Xenograft Model Antitumor Assays; Zebrafish

2020