Page last updated: 2024-08-21

oxazoles and eperezolid

oxazoles has been researched along with eperezolid in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	24 (80.00)	18.2507
2000's	6 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barbachyn, MR; Brickner, SJ; Ford, CW; Garmon, SA; Grega, KC; Hendges, SK; Hutchinson, DK; Manninen, PR; Toops, DS; Ulanowicz, DA; Zurenko, GE	1
Barbachyn, MR; Brickner, SJ; Ford, CW; Hamel, JC; Hutchinson, DK; Moerman, JK; Stapert, D; Wilson, DM; Yancey, RJ	1
Eliopoulos, GM; Gold, HS; Moellering, RC; Wennersten, CB	1
Appelbaum, PC; Jacobs, MR; Spangler, SK	1
Kaplan, SL; Lamberth, LB; Mason, EO	1
Allison, JW; Barbachyn, MR; Brickner, SJ; Glickman, SE; Hutchinson, DK; Kilburn, JO; Schaadt, RD; Yagi, BH; Zurenko, GE	1
Erwin, ME; Johnson, DM; Jones, RN	1
Kaatz, GW; Seo, SM	1
Drenning, SD; Mulazimoglu, L; Yu, VL	1
Jorgensen, JH; McElmeel, ML; Trippy, CW	1
Erwin, ME; Jones, RN; Worth, S	1
Batts, DH; Daley-Yates, PT; Pawsey, SD; Schaadt, RD; Stalker, DJ; Zurenko, GE	1
Lin, AH; Marotti, KR; Murray, RW; Vidmar, TJ	1
Buysse, JM; Demyan, WF; Dunyak, DS; Lin, AH; Marotti, KR; Melchior, EP; Murray, RW; Shinabarger, DL; Swaney, SM	1
Biedenbach, DJ; Jones, RN	1
Aeschlimann, JR; Cappelletty, DM; Kaatz, GW; Moldovan, T; Rybak, MJ	1
Marotti, KR; Murray, RW; Schaadt, RD; Zurenko, GE	1
Adamski, JL; Allwine, DA; Barbachyn, MR; Brickner, SJ; Burton, PS; Conradi, RA; Ford, CW; Grega, KC; Hutchinson, DK; Jensen, RM; Klock, JL; Tucker, JA; Zurenko, GE	1
Chase, S; Cynamon, MH; Klemens, SP; Sharpe, CA	1
Barbadora, K; Green, M; Kearney, JA; Mason, EO; Wald, ER	1
Fresnadillo, MJ; García-Rodríguez, JA; García-Sánchez, E; García-Sánchez, JE; Montes Martínez, I; Trujillano-Martín, I	1
Hoppe, JE	1
Eliopoulos, GM; Moellering, RC; Schülin, T; Thauvin-Eliopoulos, C	1
Abdel-Rahman, SM; Kearns, GL	1
Diekema, DI; Jones, RN	1
Bowersock, TL; Ford, CW; Portis, ES; Prescott, JF; Robison, DA; Salmon, SA; Watts, JL	1
Boggs, CM; Bush, K; Foleno, BD; Goldschmidt, RM; Hlasta, DJ; Weidner-Wells, MA; Wira, E	1
Colleran, E; Cormican, M; Curtin, J; Fleming, G; Keelehan, J	1
Kapadnis, PB; Lohray, BB; Lohray, VB; Pandya, P; Srivastava, BK	1
Brieland, JK; Chosay, JG; Leach, KL; Nagiec, EE; Ross, DE; Swaney, SM; Wu, L	1

Reviews

2 review(s) available for oxazoles and eperezolid

Article	Year
An update on the oxazolidinone antibiotics. The Pediatric infectious disease journal, 1999, Volume: 18, Issue:12 Topics: Acetamides; Anti-Infective Agents; Drug Resistance, Microbial; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones	1999
Oxazolidinones: a review. Drugs, 2000, Volume: 59, Issue:1 Topics: Acetamides; Animals; Anti-Infective Agents; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones	2000

Trials

1 trial(s) available for oxazoles and eperezolid

Article	Year
Serum inhibitory titers and serum bactericidal titers for human subjects receiving multiple doses of the antibacterial oxazolidinones eperezolid and linezolid. Diagnostic microbiology and infectious disease, 1997, Volume: 28, Issue:4 Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Injections, Intravenous; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae	1997

Article

Year

Serum inhibitory titers and serum bactericidal titers for human subjects receiving multiple doses of the antibacterial oxazolidinones eperezolid and linezolid.

Diagnostic microbiology and infectious disease, 1997, Volume: 28, Issue:4

Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Injections, Intravenous; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae

1997

Other Studies

27 other study(ies) available for oxazoles and eperezolid

Article	Year
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Acetamides; Animals; Anti-Infective Agents; Dogs; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Linezolid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats	1996
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:6 Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Injections, Intravenous; Injections, Subcutaneous; Linezolid; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin	1996
In vitro activities in new oxazolidinone antimicrobial agents against enterococci. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7 Topics: Acetamides; Anti-Bacterial Agents; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones	1996
Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:2 Topics: Acetamides; Amino Acid Sequence; Anti-Bacterial Agents; Cephalosporins; Linezolid; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazoles; Oxazolidinones; Penicillin Resistance; Streptococcus pneumoniae; Virginiamycin	1996
In vitro activities of oxazolidinones U-100592 and U-100766 against penicillin-resistant and cephalosporin-resistant strains of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4 Topics: Acetamides; Anti-Bacterial Agents; beta-Lactam Resistance; Ceftriaxone; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillins; Streptococcus pneumoniae	1996
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4 Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin	1996
In vitro antimicrobial activities and spectra of U-100592 and U-100766, two novel fluorinated oxazolidinones. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3 Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Bacteria, Anaerobic; Diffusion; Gram-Negative Bacteria; Gram-Positive Cocci; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones	1996
In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Nafcillin; Oxazoles; Oxazolidinones; Penicillins; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin	1996
In vitro activities of two novel oxazolidinones (U100592 and U100766), a new fluoroquinolone (trovafloxacin), and dalfopristin-quinupristin against Staphylococcus aureus and Staphylococcus epidermidis. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:10 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Synergism; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Naphthyridines; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Virginiamycin	1996
In vitro activities of the oxazolidinone antibiotics U-100592 and U-100766 against Staphylococcus aureus and coagulase-negative Staphylococcus species. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2 Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Colony Count, Microbial; Linezolid; Oxazoles; Oxazolidinones; Staphylococcus; Staphylococcus aureus	1997
Quality control guidelines for amoxicillin, amoxicillin-clavulanate, azithromycin, piperacillin-tazobactam, roxithromycin, ticarcillin, ticarcillin-clavulanate, trovafloxacin (CP 99,219), U-100592, and U-100766 for various National Committee for Clinical Diagnostic microbiology and infectious disease, 1996, Volume: 24, Issue:2 Topics: Acetamides; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Azithromycin; Clavulanic Acids; Fluoroquinolones; Humans; Linezolid; Microbial Sensitivity Tests; Naphthyridines; Oxazoles; Oxazolidinones; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality Control; Roxithromycin; Ticarcillin	1996
The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:10 Topics: Acetamides; Anti-Bacterial Agents; Chloramphenicol; Escherichia coli; Kinetics; Lincomycin; Oxazoles; Oxazolidinones; Puromycin; Ribosomes	1997
Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:10 Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Coliphages; Culture Media; Escherichia coli; Linezolid; Microbial Sensitivity Tests; N-Formylmethionine; Oxazoles; Oxazolidinones; Poly U; Polyribosomes; Protein Biosynthesis; Ribosomes; Transcription, Genetic	1997
Disk diffusion test interpretive criteria and quality control recommendations for testing linezolid (U-100766) and eperezolid (U-100592) with commercially prepared reagents. Journal of clinical microbiology, 1997, Volume: 35, Issue:12 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Evaluation Studies as Topic; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indicators and Reagents; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Quality Control	1997
Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Ente Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:3 Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Enterococcus faecalis; Enterococcus faecium; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin	1998
Ribosomes from an oxazolidinone-resistant mutant confer resistance to eperezolid in a Staphylococcus aureus cell-free transcription-translation assay. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4 Topics: Acetamides; Anti-Bacterial Agents; Cell-Free System; Mutation; Oxazoles; Oxazolidinones; Protein Biosynthesis; Ribosomes; Staphylococcus aureus; Transcription, Genetic	1998
Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring. Journal of medicinal chemistry, 1998, Sep-10, Volume: 41, Issue:19 Topics: Acetamides; Anti-Bacterial Agents; Caco-2 Cells; Enterococcus faecalis; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Permeability; Piperazines; Pyridines; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Structure-Activity Relationship; Triazenes	1998
Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:5 Topics: Acetamides; Animals; Anti-Bacterial Agents; Antitubercular Agents; Female; Linezolid; Mice; Mycobacterium tuberculosis; Oxazoles; Oxazolidinones; Tuberculosis	1999
In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae. International journal of antimicrobial agents, 1999, Volume: 12, Issue:2 Topics: Acetamides; Acute Disease; Anti-Bacterial Agents; Child; Clindamycin; Drug Resistance, Microbial; Erythromycin; Humans; Linezolid; Microbial Sensitivity Tests; Otitis Media; Oxazoles; Oxazolidinones; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae	1999
In vitro activities of five new antimicrobial agents against Brucella melitensis. International journal of antimicrobial agents, 1999, Volume: 12, Issue:2 Topics: Acetamides; Anti-Bacterial Agents; Brucella melitensis; Humans; Linezolid; Microbial Sensitivity Tests; Mupirocin; Oxazoles; Oxazolidinones; Rifabutin; Virginiamycin	1999
In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to the novel oxazolidinones eperezolid (PNU-100592) and linezolid (PNU-100766) Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:3 Topics: Acetamides; Anti-Bacterial Agents; Bordetella; Bordetella pertussis; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones	1999
Activities of the oxazolidinones linezolid and eperezolid in experimental intra-abdominal abscess due to Enterococcus faecalis or vancomycin-resistant Enterococcus faecium. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:12 Topics: Abdominal Abscess; Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Linezolid; Male; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vancomycin	1999
MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animals. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:5 Topics: Acetamides; Animals; Anti-Bacterial Agents; Horses; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rhodococcus equi	2000
Novel piperidinyloxy oxazolidinone antimicrobial agents. Bioorganic & medicinal chemistry letters, 2001, Jul-23, Volume: 11, Issue:14 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Piperidines; Staphylococcus aureus	2001
Linezolid compared with eperezolid, vancomycin, and gentamicin in an in vitro model of antimicrobial lock therapy for Staphylococcus epidermidis central venous catheter-related biofilm infections. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:10 Topics: Acetamides; Anti-Infective Agents; Biofilms; Catheterization, Central Venous; Catheters, Indwelling; Colony Count, Microbial; Gentamicins; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Sodium Chloride; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin	2003
Novel tetrahydro-thieno pyridyl oxazolidinone: an antibacterial agent. Bioorganic & medicinal chemistry, 2004, Sep-01, Volume: 12, Issue:17 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pyridines; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin	2004
Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:9 Topics: Acetamides; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Flow Cytometry; Humans; In Vitro Techniques; K562 Cells; Linezolid; Mitochondria, Heart; Oxazoles; Oxazolidinones; Protein Synthesis Inhibitors; Rats; Structure-Activity Relationship	2005