oxazoles has been researched along with doxazolidine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barthel, BL; Burkhart, DJ; Hagadorn, JR; Koch, TH; Post, GC | 1 |
| Barthel, BL; Chan, DC; Coldren, CD; Koch, GG; Koch, TH; Polinkovsky, M; Rudnicki, DL; Sun, H; Zhang, Z | 1 |
| Barthel, BL; Burkhart, DJ; Colvin, SM; Kirby, TP; Koch, TH; Rudnicki, DL | 1 |
| Barthel, B; Koch, TH; Shi, D; Xiao, D; Yan, B; Yang, D | 1 |
| Charpentier, M; Guo, L; Lu, W; Xiao, D; Yan, B; Yang, D | 1 |
| Barthel, BL; Koch, GG; Koch, TH; Mooz, EL; Wiener, LE | 1 |
| Barthel, BL; Ganesh, AN; Koch, TH; Logie, J; McLaughlin, CK; Shoichet, BK; Shoichet, MS | 1 |
| Balabanova, A; Bargmann, A; Frakes, SA; Grimm, J; Koch, TH; Tamura, R; Yin, H | 1 |
| Al-Awar, R; Aman, A; Barthel, BL; Cogan, P; Ganesh, AN; Koch, TH; Logie, J; Shoichet, BK; Shoichet, MS | 1 |
| Li, J; Li, X; Liu, P | 1 |
10 other study(ies) available for oxazoles and doxazolidine
| Article | Year |
|---|---|
Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cross-Linking Reagents; Crystallography, X-Ray; DNA; Doxorubicin; Drug Screening Assays, Antitumor; Drug Stability; Humans; Hydrolysis; Models, Molecular; Oxazoles; Prodrugs | 2005 |
Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carbamates; Carboxylesterase; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Enzymologic; Humans; Mice; Myocytes, Cardiac; Neoplasms; Oxazoles; Prodrugs; Rats; Regression Analysis | 2009 |
Synthesis and biological characterization of protease-activated prodrugs of doxazolidine.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Doxorubicin; Drug Stability; Humans; Kinetics; Oxazoles; Peptide Hydrolases; Phosphates; Proteolysis | 2012 |
Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.
Topics: Animals; Anti-Obesity Agents; Antineoplastic Agents; Camptothecin; Carboxylic Ester Hydrolases; Cell Line; Cell Survival; Doxorubicin; Drug Interactions; Female; Humans; Irinotecan; Lactones; Liver; Male; Mice; Orlistat; Oxazoles; Prodrugs; Rats; Species Specificity | 2013 |
Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.
Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Doxorubicin; Fluorouracil; Gene Expression Regulation, Neoplastic; Hep G2 Cells; HT29 Cells; Humans; Irinotecan; Mice; Oxazoles; RNA Stability; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Correlation of in Situ Oxazolidine Formation with Highly Synergistic Cytotoxicity and DNA Cross-Linking in Cancer Cells from Combinations of Doxorubicin and Formaldehyde.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cross-Linking Reagents; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Esterases; Formaldehyde; Humans; Liver; Molecular Structure; Oxazoles; Prodrugs; Structure-Activity Relationship; Swine; Tumor Cells, Cultured | 2016 |
Leveraging Colloidal Aggregation for Drug-Rich Nanoparticle Formulations.
Topics: Colloids; Doxorubicin; Drug Carriers; Drug Delivery Systems; Micelles; Nanoparticles; Oxazoles; Polymers | 2017 |
Photoactivatable Prodrug of Doxazolidine Targeting Exosomes.
Topics: Amino Acid Sequence; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Cross-Linking Reagents; Doxorubicin; Exosomes; Humans; Nitrobenzenes; Oxazoles; Photolysis; Prodrugs; Ultraviolet Rays | 2019 |
Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence.
Topics: Animals; Antineoplastic Agents; Carbamates; Colloids; Doxorubicin; Drug Stability; Excipients; Female; Fulvestrant; Humans; MCF-7 Cells; Mice; Neoplasm Transplantation; Oxazoles; Polysorbates; Prodrugs; Proof of Concept Study; Serum | 2019 |
Synthesis of Acid-Labile Poly(Doxazolidine) as a Polyprodrug with an Ultra-High Drug Content for Self-Delivery of High-Performance Chemotherapeutics.
Topics: Acetates; Antineoplastic Agents; Cell Proliferation; Cell Survival; Doxorubicin; Drug Delivery Systems; Drug Liberation; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Nanoparticles; Oxazoles; Polymers; Prodrugs | 2020 |