Page last updated: 2024-08-21

oxazoles and disorazol a

oxazoles has been researched along with disorazol a in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gerth, K; Höfle, G; Irschik, H; Jansen, R; Reichenbach, H1
Elnakady, YA; Lünsdorf, H; Reichenbach, H; Sasse, F1
Irschik, H; Kopp, M; Müller, R; Pradella, S1
Carvalho, R; Gramajo, H; Julien, B; Reid, R; Viswanathan, N1
Bian, X; Herrmann, J; Hu, S; Müller, R; Raju, R; Tu, Q; Zhang, Y1
Chhatwal, GS; Müller, R; Rohde, M; Rox, K1

Other Studies

6 other study(ies) available for oxazoles and disorazol a

ArticleYear
Disorazol A, an efficient inhibitor of eukaryotic organisms isolated from myxobacteria.
    The Journal of antibiotics, 1995, Volume: 48, Issue:1

    Topics: Animals; Antifungal Agents; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Fibroblasts; Fungi; HeLa Cells; Humans; Macromolecular Substances; Mice; Microbial Sensitivity Tests; Myxococcales; Oxazoles

1995
Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells.
    Biochemical pharmacology, 2004, Mar-01, Volume: 67, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Biopolymers; Cell Cycle; Cell Division; Cells, Cultured; G2 Phase; Humans; K562 Cells; KB Cells; Microtubules; Mitosis; Oxazoles; Tubulin; U937 Cells

2004
Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes.
    Chembiochem : a European journal of chemical biology, 2005, Volume: 6, Issue:7

    Topics: Amino Acid Sequence; Blotting, Southern; Chromatography, High Pressure Liquid; DNA Transposable Elements; Electroporation; Molecular Sequence Data; Multigene Family; Myxococcales; Oxazoles; Polyketide Synthases; Protein Engineering; Recombinant Proteins

2005
The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation.
    Gene, 2005, Oct-10, Volume: 359

    Topics: Amino Acid Sequence; Catalytic Domain; Dimerization; DNA, Bacterial; Gene Order; Microtubules; Models, Chemical; Molecular Sequence Data; Multigene Family; Myxococcales; Oxazoles; Polyketide Synthases; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tubulin

2005
Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering.
    Scientific reports, 2016, Feb-15, Volume: 6

    Topics: Biosynthetic Pathways; Cell Line, Tumor; Chromosomes, Artificial, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Genetic Engineering; Humans; Multigene Family; Mutagenesis; Myxococcus xanthus; Oxazoles; Recombination, Genetic

2016
Disorazoles Block Group A Streptococcal Invasion into Epithelial Cells Via Interference with the Host Factor Ezrin.
    Cell chemical biology, 2017, Feb-16, Volume: 24, Issue:2

    Topics: Anti-Bacterial Agents; Cytoskeletal Proteins; Epithelial Cells; Humans; Oxazoles; Streptococcus pyogenes; Tumor Cells, Cultured

2017