oxazoles has been researched along with conglobatin in 9 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 7 (77.78) | 24.3611 |
2020's | 2 (22.22) | 2.80 |
Authors | Studies |
---|---|
Huang, W; Wu, QD; Xu, JH; Ye, M; Zhang, LR; Zhang, M; Zheng, W | 1 |
Cao, PR; Huang, W; Kong, YL; Wu, QD; Xu, JH; Ye, M; Zhang, M; Zheng, W | 1 |
Cao, HH; Chen, B; Chen, H; Du, ZP; Huang, W; Jia, W; Jiang, H; Li, EM; Li, LY; Liao, LD; Xie, JJ; Xie, YM; Xu, LY; Xu, XE; Zeng, FM; Zhang, YL; Zheng, W | 1 |
Dias, LC; Leadlay, PF; Murphy, AC; Prediger, P; Samborskyy, M; Zhou, Y | 1 |
Cao, P; Chen, L; Huang, W; Kong, Y; Luo, Y; She, B; Xu, J; Ye, M | 1 |
Abankwa, D; Aittokallio, T; Guzmán, C; Jaiswal, A; Lacey, E; Lectez, B; Najumudeen, AK; Oetken-Lindholm, C; Posada, IM; Siljamäki, E | 1 |
Fu, L; Li, P; Ma, C; Wu, M; Xu, J; Ye, S; Zhang, Z | 1 |
Booth, TJ; Chooi, YH; Lacey, E; Lacey, HJ; Piggott, AM; Rutledge, PJ; Vuong, D | 1 |
Chen, R; Cowled, MS; Lacey, E; Lacey, H; Piggott, AM; Rutledge, PJ; Vuong, D | 1 |
9 other study(ies) available for oxazoles and conglobatin
Article | Year |
---|---|
FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Chaperonins; Female; HSP90 Heat-Shock Proteins; Humans; Macrolides; MCF-7 Cells; Multiprotein Complexes; Oxazoles; Protein Binding; Receptor, ErbB-2 | 2014 |
Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Immunoenzyme Techniques; Lapatinib; Mice; Mice, Inbred BALB C; Mice, Nude; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Real-Time Polymerase Chain Reaction; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
Macrolide analog F806 suppresses esophageal squamous cell carcinoma (ESCC) by blocking β1 integrin activation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Integrin beta1; Male; Mice; Mice, Nude; Oxazoles; Random Allocation; Xenograft Model Antitumor Assays | 2015 |
Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Magnetic Resonance Spectroscopy; Mass Spectrometry; Multigene Family; Oxazoles; Polyketide Synthases; Streptomyces | 2015 |
[The Hsp90 inhibitor FW-04-806 suppresses Bcr/Abl-mediated growth of leukemia cells by inhibiting proliferation and inducing apoptosis].
Topics: Apoptosis; Cell Cycle; Cell Proliferation; Fusion Proteins, bcr-abl; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Leukemia; Membrane Potential, Mitochondrial; Oxazoles; RNA, Messenger; Signal Transduction | 2015 |
Cancer stem cell drugs target K-ras signaling in a stemness context.
Topics: Calmodulin; Caveolae; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasms; Neoplastic Stem Cells; Oxazoles; Proto-Oncogene Proteins p21(ras); Pyrans; ras Proteins; Sesterterpenes | 2016 |
Reversal effect of FW-04-806, a macrolide dilactone compound, on multidrug resistance mediated by ABCB1 and ABCG2 in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; K562 Cells; KB Cells; Mice; Molecular Docking Simulation; Molecular Structure; Neoplasm Proteins; Neoplasms, Experimental; Oxazoles; Rhodamine 123; Signal Transduction; Structure-Activity Relationship | 2019 |
Conglobatins B-E: cytotoxic analogues of the C
Topics: Cell Line, Tumor; Cytotoxins; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Oxazoles; Streptomyces | 2020 |
Yeppoonic acids A - D: 1,2,4-trisubstituted arene carboxylic acid co-metabolites of conglobatin from an Australian Streptomyces sp.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Australia; Carboxylic Acids; Cell Line, Tumor; Humans; Male; Mice; Multiple Myeloma; Oxazoles; Prostatic Neoplasms; Queensland; Soil Microbiology; Streptomyces | 2022 |