oxazepam and warfarin

oxazepam has been researched along with warfarin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's4 (17.39)18.2507
2000's10 (43.48)29.6817
2010's5 (21.74)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G1
Briand, X; Faller, B; Lázaro, E; Lowe, PJ1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Azas, N; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Courtioux, B; Fairlamb, A; Hutter, S; Laget, M; Moreau, A; Mothes, E; Paloque, L; Pedron, J; Pratviel, G; Sournia-Saquet, A; Stigliani, JL; Valentin, A; Vendier, L; Verhaeghe, P; Wyllie, S1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K1
Ciana, A; Crescenzi, V; Manzini, G1
Hage, DS; Noctor, TA; Wainer, IW1
Bertucci, C; Domenici, E; Salvadori, P; Wainer, IW1
Fitos, I; Lagercrantz, C; Larsson, T; Simonyi, M; Sjöholm, I; Tegyey, Z1
Chosson, E; Farinotti, R; Gimenez, F; Uzan, S; Wainer, IW1
Mangin, C; Millot, MC; Sébille, B1
Bäurer, S; Bonnet, P; Bourg, S; Ferri, M; Lämmerhofer, M; Ma, CMA; Raimbault, A; West, C1

Reviews

1 review(s) available for oxazepam and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for oxazepam and warfarin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Antiprotozoal Agents; Cell Survival; Dose-Response Relationship, Drug; Electrochemical Techniques; Hep G2 Cells; Humans; Kinetoplastida; Leishmania infantum; Molecular Structure; Nitroquinolines; Nitroreductases; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanosoma brucei brucei

2018
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry

2020
The interaction of serum albumins with various drugs in aqueous solution. Gel permeation, calorimetric, and fluorescence data.
    Biophysical chemistry, 1979, Volume: 10, Issue:3-4

    Topics: Animals; Binding Sites; Calorimetry; Cattle; Chromatography, Gel; Fluoresceins; Humans; Kinetics; Oxazepam; Phenylbutazone; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Warfarin

1979
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase.
    Journal of chromatography, 1992, Jun-10, Volume: 577, Issue:2

    Topics: Allosteric Site; Binding, Competitive; Caprylates; Chromatography, High Pressure Liquid; Humans; Ketoprofen; Oxazepam; Pharmaceutical Preparations; Phenylbutazone; Serum Albumin; Stereoisomerism; Suprofen; Tolbutamide; Warfarin

1992
Use of a human serum albumin-based high-performance liquid chromatography chiral stationary phase for the investigation of protein binding: detection of the allosteric interaction between warfarin and benzodiazepine binding sites.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Benzodiazepines; Chromatography, High Pressure Liquid; Humans; Lorazepam; Oxazepam; Protein Binding; Serum Albumin; Stereoisomerism; Warfarin

1991
Stereoselective binding of 3-acetoxy-, and 3-hydroxy-1,4-benzodiazepine-2-ones to human serum albumin. Selective allosteric interaction with warfarin enantiomers.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Benzodiazepines; Diazepam; Humans; Lorazepam; Oxazepam; Research Design; Serum Albumin; Stereoisomerism; Structure-Activity Relationship; Ultrafiltration; Warfarin

1986
Influence of specific albumin ligand markers used as modifiers on the separation of benzodiazepine enantiomers by chiral liquid chromatography on a human serum albumin column.
    Chirality, 1993, Volume: 5, Issue:2

    Topics: Anti-Anxiety Agents; Chromatography, Affinity; Chromatography, Liquid; Humans; Ligands; Lorazepam; Oxazepam; Serum Albumin; Stereoisomerism; Temazepam; Warfarin

1993
Enantiomeric properties of human albumin immobilized on porous silica supports coated with polymethacryloyl chloride.
    Journal of chromatography. A, 1997, Jul-25, Volume: 776, Issue:1

    Topics: Affinity Labels; Buffers; Humans; Indicators and Reagents; Oxazepam; Phenylalanine; Polymethacrylic Acids; Porosity; Serum Albumin; Silicon Dioxide; Stereoisomerism; Tryptophan; Warfarin

1997
Cinchona-based zwitterionic stationary phases: Exploring retention and enantioseparation mechanisms in supercritical fluid chromatography with a fragmentation approach.
    Journal of chromatography. A, 2020, Feb-08, Volume: 1612

    Topics: Chromatography, Supercritical Fluid; Cinchona; Cluster Analysis; Discriminant Analysis; Hydrogen Bonding; Ions; Oxazepam; Stereoisomerism; Warfarin

2020