oxazepam and propranolol

oxazepam has been researched along with propranolol in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199012 (30.77)18.7374
1990's4 (10.26)18.2507
2000's14 (35.90)29.6817
2010's8 (20.51)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Coassolo, P; Lavé, T; Schneider, G1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G1
Briand, X; Faller, B; Lázaro, E; Lowe, PJ1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Azas, N; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Courtioux, B; Fairlamb, A; Hutter, S; Laget, M; Moreau, A; Mothes, E; Paloque, L; Pedron, J; Pratviel, G; Sournia-Saquet, A; Stigliani, JL; Valentin, A; Vendier, L; Verhaeghe, P; Wyllie, S1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K1
Dahlöf, C1
Døssing, M; Hamberg, O; Loft, S; Olesen, KL; Sonne, J; Thyssen, H; Victor, MA; Vollmer-Larsen, A1
Dahlöf, C; Dimenäs, E; Olofsson, B1
McDevitt, DG1
Currie, D; Lewis, RV; McDevitt, DG; Nicholson, AN; Wright, NA1
Currie, D; McDevitt, DG; Nicholson, AN; Wright, NA; Zetlein, MB1
Naess, K1
Erkkola, R; Iisalo, E; Punnonen, R2
Berger, BD; Stein, L; Wise, CD1
Kulik, AV; Wilbur, R1
Goch, JH; Kowalski, J; Tkaczewski, W; Wichan, P1
Davis, JM; Dysken, MW; Hicks, R; Lazarus, L; Lesser, J; Ripeckyj, A1
Coffman, BL; King, CD; Rios, GR; Tephly, TR1
Juvonen, R; Korhonen, LE; Pelkonen, O; Raunio, H; Tolonen, A; Turpeinen, M; Uusitalo, J1
Billiot, E; Billiot, F; Warner, IM1

Reviews

3 review(s) available for oxazepam and propranolol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The pharmacokinetics of psychotropic medication in the elderly: a review.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:10

    Topics: Aged; Alcoholism; Analgesics; Antidepressive Agents, Tricyclic; Barbiturates; Biological Availability; Biotransformation; Chlorpromazine; Drug Interactions; Flurazepam; Humans; Intestinal Absorption; Kidney; Kinetics; Lithium; Monoamine Oxidase Inhibitors; Nitrazepam; Oxazepam; Parasympatholytics; Physostigmine; Propranolol; Psychotropic Drugs; Tobacco Use Disorder

1981

Trials

7 trial(s) available for oxazepam and propranolol

ArticleYear
Single dose pharmacokinetics and pharmacodynamics of oral oxazepam during concomitant administration of propranolol and labetalol.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:1

    Topics: Adult; Drug Interactions; Female; Humans; Labetalol; Male; Oxazepam; Propranolol; Psychomotor Performance; Reaction Time

1990
Documentation of an instrument for assessment of subjective CNS-related symptoms during cardiovascular pharmacotherapy.
    Cardiovascular drugs and therapy, 1989, Volume: 3, Issue:6

    Topics: Brain; Cardiovascular Agents; Double-Blind Method; Humans; Oxazepam; Propranolol; Reproducibility of Results; Surveys and Questionnaires

1989
Beta-blockers and psychometric performance: studies in normal volunteers.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adrenergic beta-Antagonists; Atenolol; Diazepam; Dose-Response Relationship, Drug; Humans; Lipid Metabolism; Nadolol; Oxazepam; Propanolamines; Propranolol; Psychometrics; Psychomotor Performance; Random Allocation; Reaction Time; Reference Values; Solubility; Time Factors

1985
Central effects of beta-adrenoceptor antagonists. I--Performance and subjective assessments of mood.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Attention; Double-Blind Method; Electroencephalography; Emotions; Flicker Fusion; Heart Rate; Humans; Male; Memory, Short-Term; Oxazepam; Propranolol; Psychomotor Performance; Random Allocation; Reaction Time

1988
Central effects of beta-adrenoceptor antagonists. II--Electroencephalogram and body sway.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Atenolol; Electroencephalography; Humans; Oxazepam; Postural Balance; Propranolol

1988
The effect of propranolol and oxazepam on some vegetative menopausal symptoms.
    Annals of clinical research, 1973, Volume: 5, Issue:4

    Topics: Adult; Blood Pressure; Castration; Depression, Chemical; Electrocardiography; Female; Heart Rate; Humans; Menopause; Oxazepam; Propranolol; Sweating; Sympathetic Nervous System; Valsalva Maneuver

1973
[Ergometric test in sympatheticotonia after administration of propranolol, pindolol, verapamil and oxazepam].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jun-09, Volume: 35, Issue:23

    Topics: Adolescent; Adrenergic Fibers; Adult; Clinical Trials as Topic; Exercise Test; Heart; Heart Failure; Humans; Male; Oxazepam; Pindolol; Propranolol; Verapamil

1980

Other Studies

29 other study(ies) available for oxazepam and propranolol

ArticleYear
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin

2008
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Antiprotozoal Agents; Cell Survival; Dose-Response Relationship, Drug; Electrochemical Techniques; Hep G2 Cells; Humans; Kinetoplastida; Leishmania infantum; Molecular Structure; Nitroquinolines; Nitroreductases; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanosoma brucei brucei

2018
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry

2020
Minor Symptoms Evaluation (MSE) Profile--a questionnaire for assessment of subjective CNS-related symptoms.
    Scandinavian journal of primary health care. Supplement, 1990, Volume: 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzodiazepines; Central Nervous System Diseases; Health Status; Humans; Migraine Disorders; Oxazepam; Propranolol; Quality of Life; Reproducibility of Results; Surveys and Questionnaires

1990
Beta-blockers, mood and behaviour.
    Drug and therapeutics bulletin, 1988, Sep-19, Volume: 26, Issue:19

    Topics: Adult; Affect; Atenolol; Humans; Male; Memory, Short-Term; Oxazepam; Propranolol; Psychomotor Performance

1988
[Brief characteristics of different "sedatives"].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Sep-10, Volume: 94, Issue:25

    Topics: Anthracenes; Antidepressive Agents; Benzodiazepinones; Chlordiazepoxide; Diazepam; Hypnotics and Sedatives; Meprobamate; Oxazepam; Propranolol; Tranquilizing Agents

1974
Benzodiazepines: anxiety-reducing activity by reduction of serotonin turnover in the brain.
    Science (New York, N.Y.), 1972, Jul-14, Volume: 177, Issue:4044

    Topics: Animals; Anxiety; Behavior, Animal; Benzazepines; Brain; Depression, Chemical; Dopamine; Drug Antagonism; Drug Interactions; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Normetanephrine; Oxazepam; Phenothiazines; Phentolamine; Propranolol; Rats; Reinforcement Schedule; Serotonin; Serotonin Antagonists

1972
The effect of bilateral ovarectomy on sympathetic cardiovascular reflexes and the treatment of the postoperative vegetative syndrome with propranolol and oxazepam.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1971, Volume: 9

    Topics: Blood Pressure; Castration; Female; Heart Rate; Humans; Middle Aged; Oxazepam; Propranolol; Tachycardia; Valsalva Maneuver; Vasomotor System

1971
Abstinence syndrome from therapeutic doses of oxazepam.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:4

    Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazepam; Panic; Paresthesia; Propranolol; Substance Withdrawal Syndrome

1983
The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:1

    Topics: Androgens; Androsterone; Cell Line; Gene Expression; Glucuronates; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Menthol; Narcotics; Oxazepam; Propranolol; Recombinant Proteins; Xenobiotics

1998
Cytochrome P450 (CYP) inhibition screening: comparison of three tests.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Oct-01, Volume: 29, Issue:2

    Topics: Citalopram; Cytochrome P-450 Enzyme Inhibitors; Diazepam; Enzyme Inhibitors; Fluoxetine; Humans; Oxazepam; Propranolol; Sotalol

2006
Optimization of 12 chiral analytes with 8 polymeric surfactants.
    Journal of chromatographic science, 2008, Volume: 46, Issue:9

    Topics: Alprenolol; Amino Acids; Benzodiazepinones; Buffers; Diamines; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Lorazepam; Naphthalenes; Naphthols; Organophosphates; Oxazepam; Oxprenolol; Propanolamines; Propranolol; Stereoisomerism; Surface-Active Agents; Temazepam

2008