oxazepam and naloxone

oxazepam has been researched along with naloxone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's2 (10.53)18.2507
2000's8 (42.11)29.6817
2010's5 (26.32)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Coassolo, P; Lavé, T; Schneider, G1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Davis, DC; Holtzman, SG; Shannon, HE1
Holtzman, SG; Shannon, HE1
Cooper, SJ1
Braccia, G; Demaria, PA; Rodgers, C1
Bocchi, C; Delsignore, R; Fontanesi, B; Gerra, G; Rustichelli, P; Timpano, M; Zaimovic, A; Zambelli, U1
Docci, L; Fowler, S; Krähenbühl, S; Parrott, N; Umehara, K1

Reviews

3 review(s) available for oxazepam and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for oxazepam and naloxone

ArticleYear
Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance.
    Journal of substance abuse treatment, 2000, Volume: 18, Issue:2

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; GABA Agents; Heroin Dependence; Humans; Inactivation, Metabolic; Ketoprofen; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxazepam; Patient Compliance; Substance Withdrawal Syndrome; Treatment Outcome

2000

Other Studies

15 other study(ies) available for oxazepam and naloxone

ArticleYear
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Interactions between narcotic analgesics and benzodiazepine derivatives on behavior in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Methods; Mice; Morphine; Motor Activity; Naloxone; Oxazepam; Reaction Time

1976
Blockade of the specific lethal effects of narcotic analgesics in the mouse.
    European journal of pharmacology, 1976, Volume: 39, Issue:2

    Topics: Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Methadone; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxazepam; Trimethadione

1976
Effects of enantiomers of oxazepam sodium hemisuccinate on water intake and antagonism of picrotoxin- or naloxone-induced suppression of drinking by chlordiazepoxide in the rat.
    Neuropharmacology, 1980, Volume: 19, Issue:9

    Topics: Animals; Chlordiazepoxide; Drinking; Drug Interactions; Male; Naloxone; Oxazepam; Picrotoxin; Rats; Stereoisomerism

1980
Propofol for sedation during rapid opiate detoxification.
    The American journal of psychiatry, 1997, Volume: 154, Issue:2

    Topics: Adult; Clonidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Naloxone; Opioid-Related Disorders; Oxazepam; Propofol; Substance Withdrawal Syndrome

1997
Construction and Verification of Physiologically Based Pharmacokinetic Models for Four Drugs Majorly Cleared by Glucuronidation: Lorazepam, Oxazepam, Naloxone, and Zidovudine.
    The AAPS journal, 2020, 10-08, Volume: 22, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Cell Culture Techniques; Cells, Cultured; Coculture Techniques; Datasets as Topic; Female; Glucuronides; Glucuronosyltransferase; Hepatocytes; Humans; Intestines; Kidney; Liver; Lorazepam; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Models, Biological; Naloxone; Oxazepam; Young Adult; Zidovudine

2020