Compounds > oxazepam

oxazepam and metyrapone

oxazepam has been researched along with metyrapone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's10 (90.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goeders, NE; Guerin, GF1
Casso, S; DeMuth, G; Fox, BS; Goeders, NE; Hefti, F; Kablinger, AS; Lindner, MA; McCarthy, BG; McNair, LA1
Azar, MR; Cohen, A; Fox, BS; George, O; Goeders, NE; Koob, GF1
Cornett, EM; Goeders, NE; Guerin, GF; Keller, CM1
Goeders, NE; Guerin, GF; Schmoutz, CD2
Dhungana, S; Goeders, NE; Guerin, GF; Runyon, SP; Schmoutz, CD1
Breaux, KN; Goeders, NE; Keller, CM1
Goeders, NE; Keller, CM1

Reviews

2 review(s) available for oxazepam and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions.
    Advances in pharmacology (San Diego, Calif.), 2014, Volume: 69

    Topics: Animals; Anti-Anxiety Agents; Cocaine-Related Disorders; Humans; Metyrapone; Oxazepam; Stress, Psychological; Substance-Related Disorders; Treatment Outcome

2014

Trials

1 trial(s) available for oxazepam and metyrapone

ArticleYear
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:7

    Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Female; GABA Agonists; Humans; Louisiana; Male; Metyrapone; Middle Aged; Oxazepam; Patient Compliance; Patient Dropouts; Pilot Projects; Secondary Prevention; Steroid 11-beta-Hydroxylase; Substance Withdrawal Syndrome

2012

Other Studies

8 other study(ies) available for oxazepam and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 91, Issue:1

    Topics: Animals; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Dose-Response Relationship, Drug; Drug Combinations; Eating; Enzyme Inhibitors; Extinction, Psychological; Hypnotics and Sedatives; Male; Metyrapone; Oxazepam; Rats; Rats, Wistar; Self Administration; Substance Abuse, Intravenous

2008
Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats.
    Psychopharmacology, 2012, Volume: 223, Issue:1

    Topics: Animals; Benzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Hypnotics and Sedatives; Infusions, Intravenous; Male; Metyrapone; Nicotine; Oxazepam; Quinoxalines; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Smoking Cessation; Varenicline

2012
Combinations of oxazepam and metyrapone attenuate cocaine and methamphetamine cue reactivity.
    Drug and alcohol dependence, 2013, Dec-01, Volume: 133, Issue:2

    Topics: Amphetamine-Related Disorders; Analysis of Variance; Animals; Central Nervous System Stimulants; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Cues; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Food; Hypnotics and Sedatives; Male; Methamphetamine; Metyrapone; Oxazepam; Pharmaceutical Vehicles; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome

2013
The extra-adrenal effects of metyrapone and oxazepam on ongoing cocaine self-administration.
    Brain research, 2014, Aug-05, Volume: 1575

    Topics: Adrenal Medulla; Adrenalectomy; Animals; Anti-Anxiety Agents; Cocaine; Conditioning, Operant; Corticosterone; Drug-Seeking Behavior; Extinction, Psychological; Male; Metyrapone; Oxazepam; Rats; Rats, Wistar; Self Administration; Stress, Physiological

2014
A therapeutic combination of metyrapone and oxazepam increases brain levels of GABA-active neurosteroids and decreases cocaine self-administration in male rats.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Desoxycorticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; GABA Modulators; Male; Metyrapone; Motivation; Oxazepam; Pregnanolone; Rats, Wistar; Self Administration

2015
Effects of the combination of metyrapone and oxazepam on cocaine-induced increases in corticosterone in the medial prefrontal cortex and nucleus accumbens.
    Psychoneuroendocrinology, 2017, Volume: 77

    Topics: Animals; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Enzyme Inhibitors; GABA Modulators; Male; Metyrapone; Nucleus Accumbens; Oxazepam; Prefrontal Cortex; Rats; Rats, Wistar

2017
Lack of effect of the combination of metyrapone and oxazepam on brain dopamine.
    Brain research, 2019, 12-01, Volume: 1724

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine; Dopamine Uptake Inhibitors; Male; Metyrapone; Nucleus Accumbens; Oxazepam; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration

2019