oxathiaphospholane has been researched along with diphosphoric-acid* in 1 studies
1 other study(ies) available for oxathiaphospholane and diphosphoric-acid
| Article | Year |
|---|---|
Unexpected loss of stereoselectivity in ring-opening reaction of 2-alkoxy-2-thio-1,3,2-oxathiaphospholanes with a pyrophosphate anion.
A reaction of DBU promoted ring opening in nucleoside-3'-O- and nucleoside-5'-O-(2-thio-4,4-pentamethylene-1,3,2-oxathiaphospholane) monomers with a pyrophosphate or a methylenediphosphonate anion proceeds with substantial loss of stereoselectivity. Depending on the absolute configuration of the phosphorus atom, so far widely accepted the stereoretentive mechanism of condensation is accompanied by a stereoinvertive one, most likely employing an intramolecular ligand-ligand exchange in an uncharged intermediate. Topics: Anions; Bridged Bicyclo Compounds, Heterocyclic; Diphosphates; Diphosphonates; Magnetic Resonance Spectroscopy; Nucleotides; Phosphites; Ribose; Stereoisomerism | 2015 |