oxamniquine and hycanthone

oxamniquine has been researched along with hycanthone in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199035 (81.40)18.7374
1990's7 (16.28)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Katz, N1
Woolhouse, NM1
Bueding, E; Haese, WH1
Cabeca, M; de Almeida, FM; Dias, LC; GuimarĂ£es, RX; Takeda, AK; Tchakerian, A; Vilela, MP1
Batzinger, RP; Bueding, E1
Ong, TM1
Amato Neto, V; De Carvalho, SA; Dias, LC; Pedro, RD1
Dias, LC; Goto, MM; Mafra, GL; Pedro, RJ; Rigo, E1
Adam, SE; Magzoub, M1
Hatchuel, W1
Mello, RT; Pellegrino, J; Pereira, LH1
Bartholomew, RK; Cook, JA; Jordan, P1
Bueding, E; Jansma, WB; Liu, CL; Rogers, SH1
Ellis, JH; Holden, HE; Hyneck, ML; Ray, VA1
Bowry, HN; Rees, PH; Roberts, JM; Thuku, JJ1
Cioli, D; Dias, LC; Pica-Mattoccia, L1
Cioli, D; Moroni, R; Pica-Mattoccia, L1
Bruce, JI; Tsao, GC; Wong, LJ; Wong, SS1
Brito, E; Martinelli, R; Noblat, AC; Rocha, H1
Archer, S; Cioli, D; Pica-Mattoccia, L2
Hilderson, H; Rollinson, D; Southgate, VR; Vercruysse, J1
Doenhoff, MJ; Fletcher, C; Sabah, AA; Webbe, G2
Andrade, ZA; Grimaud, JA1
Martinelli, R; Pereira, LJ; Rocha, H1
Cioli, D; Pica, L1
Cioli, D; Pica-Mattoccia, L2
Archer, S1
De Cock, KM1
Andrade, ZA; de Almeida, MA1
Andrade, ZA; Azevedo de Brito, P1
de Jesus Pedro, R; de Souza Dias, LC; Deberaldini, ER1
Gilles, HM1
Bain, J; Bickle, Q; Doenhoff, M; Nelson, G; Webbe, G1
Araujo, N; de Souza, CP; Katz, N; Pinto Dias, E1
Auguste, E; Bartholomew, RK; Cook, JA; Grist, E; Jordan, P1
Cioli, D; Dias, LC; Moroni, R; Pica-Mattoccia, L1
Awney, HA; Badawi, AF; Mostafa, MH1
Cioli, D; Novi, A; Pica-Mattoccia, L1
Badawi, AF1
Cao, X; Guzman, M; LoVerde, PT; McHardy, SF; Rugel, A; Tarpley, RS; Taylor, AB1

Reviews

5 review(s) available for oxamniquine and hycanthone

ArticleYear
Chemotherapy of Schistosomiasis mansoni.
    Advances in pharmacology and chemotherapy, 1977, Volume: 14

    Topics: Amphotericin B; Animals; Antimony; Chemosterilants; Drug Evaluation; Drug Evaluation, Preclinical; Eggs; Emetine; Humans; Hycanthone; Lucanthone; Naphthalenes; Niridazole; Nitrofurans; Organophosphorus Compounds; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Snails; Thiazoles; Thiophenes; Tubercidin

1977
Biochemical and pharmacological effects in relation to the mode of action of antischistosomal drugs.
    Biochemical pharmacology, 1979, Aug-15, Volume: 28, Issue:16

    Topics: Animals; Antimony; Carbohydrate Metabolism; Glycogen; Heterocyclic Compounds; Hycanthone; Neurotransmitter Agents; Niridazole; Oxamniquine; Schistosoma; Schistosomicides

1979
Genetic activities of hycanthone and some other antischistosomal drugs.
    Mutation research, 1978, Volume: 55, Issue:1

    Topics: Acrylamides; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; Drosophila; Genes, Dominant; Genes, Lethal; Humans; Hycanthone; Lucanthone; Mice; Mutagens; Mutation; Niridazole; Nitrofurans; Oxamniquine; Rabbits; Rats; Saccharomyces cerevisiae; Salmonella typhimurium; Schistosomicides; Species Specificity; Teratogens; Thioxanthenes; Trichlorfon

1978
The chemotherapy of schistosomiasis.
    Annual review of pharmacology and toxicology, 1985, Volume: 25

    Topics: Animals; Chemical Phenomena; Chemistry; Diphenylamine; Humans; Hycanthone; Isothiocyanates; Niridazole; Oxamniquine; Praziquantel; Pyrazines; Schistosomiasis; Schistosomicides; Thiocyanates; Thiones; Thiophenes; Trichlorfon

1985
Human schistosomiasis and its management.
    The Journal of infection, 1984, Volume: 8, Issue:1

    Topics: Animals; Humans; Hycanthone; Oxamniquine; Praziquantel; Schistosoma; Schistosomiasis; Trichlorfon

1984

Trials

1 trial(s) available for oxamniquine and hycanthone

ArticleYear
The treatment of schistosomiasis mansoni in Murang'a District, Kenya: a double blind controlled trial of three hycanthone regimens and oxamniquine.
    The American journal of tropical medicine and hygiene, 1975, Volume: 24, Issue:5

    Topics: Adolescent; Body Weight; Child; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hycanthone; Injections, Intramuscular; Kenya; Male; Nitroquinolines; Oxamniquine; Pain; Schistosoma mansoni; Schistosomiasis; Thioxanthenes; Vomiting

1975

Other Studies

37 other study(ies) available for oxamniquine and hycanthone

ArticleYear
Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Female; Hycanthone; Indazoles; Liver; Liver Neoplasms; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Thioxanthenes

1976
[Resistance to hycanthone and oxamniquine in patients with a clinical hepato-intestinal form of schistosomiasis].
    AMB : revista da Associacao Medica Brasileira, 1979, Volume: 25, Issue:2

    Topics: Adult; Animals; Drug Resistance; Female; Humans; Hycanthone; Intestinal Diseases, Parasitic; Liver Diseases, Parasitic; Male; Mice; Nitroquinolines; Oxamniquine; Schistosomiasis; Thioxanthenes

1979
Mutagenic activities in vitro and in vivo of five antischistosomal compounds.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: Animals; Female; Hycanthone; Mice; Microsomes, Liver; Mutagens; Oxamniquine; Salmonella typhimurium; Schistosoma mansoni; Schistosomicides; Trichlorfon

1977
Observations on the treatment of mansoni schistosomiasis with oxamniquine.
    Revista brasileira de pesquisas medicas e biologicas, 1979, Volume: 12, Issue:2-3

    Topics: Adolescent; Child; Child, Preschool; Feces; Female; Humans; Hycanthone; Liver; Male; Microscopy, Electron; Nitroquinolines; Oxamniquine; Salmonella Infections; Schistosoma mansoni; Schistosomiasis

1979
[A human strain of Schistosoma mansoni resistant to schistosomicides].
    Revista de saude publica, 1978, Volume: 12, Issue:1

    Topics: Drug Resistance; Humans; Hycanthone; Oxamniquine; Schistosoma mansoni

1978
Evaluation of oral therapy of mansonial schistosomiasis in the Sudan using single and multiple doses of hycanthone and oxamniquine drugs.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:2

    Topics: Animals; Drug Administration Schedule; Drug Therapy, Combination; Female; Hycanthone; Liver; Male; Nitroquinolines; Oxamniquine; Rats; Schistosoma mansoni; Schistosomiasis; Sudan; Thioxanthenes

1978
Fatal hepatic necrosis in association with hycanthone.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Nov-11, Volume: 54, Issue:20

    Topics: Chemical and Drug Induced Liver Injury; Humans; Hycanthone; Necrosis; Nitroquinolines; Oxamniquine; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Thioxanthenes; Trichlorfon

1978
Activity of known antischistosomal agents on early-developing forms of Schistosoma mansoni.
    The Journal of parasitology, 1975, Volume: 61, Issue:2

    Topics: Animals; Antimony; Diethylamines; Edetic Acid; Hycanthone; Lithium; Lucanthone; Mice; Oxamniquine; Schistosomiasis; Schistosomicides; Thiomalates; Toluidines; Trichlorfon

1975
Control of Schistosoma mansoni transmission by chemotherapy in St. Lucia. I. Results in man.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:5 Pt 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Costs and Cost Analysis; Female; Humans; Hycanthone; Infant; Male; Niridazole; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Thioxanthenes; West Indies

1977
Experimentally produced resistance of Schistosoma mansoni to hycanthone.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:5 Pt 1

    Topics: Animals; Drug Resistance; Ethidium; Female; Genes; Hybridization, Genetic; Hycanthone; Male; Mice; Niridazole; Oxamniquine; Quinacrine; Schistosoma mansoni; Thioxanthenes; Time Factors

1977
A comparative study on the genetic effects of hycanthone and oxamniquine.
    Journal of toxicology and environmental health, 1975, Volume: 1, Issue:2

    Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Chromosomes; Female; Genes, Dominant; Genes, Lethal; Humans; Hycanthone; Male; Mice; Microsomes, Liver; Mitosis; Mutagens; Mutation; Nitroquinolines; Oxamniquine; Pregnancy; Salmonella typhimurium; Thioxanthenes; Time Factors

1975
Genetic complementation analysis of two independently isolated hycanthone-resistant strains of Schistosoma mansoni.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Animals; Brazil; Crosses, Genetic; DNA; Drug Resistance; Genes, Helminth; Genes, Recessive; Genetic Complementation Test; Hycanthone; Mice; Oxamniquine; Puerto Rico; Schistosoma mansoni; Species Specificity

1992
Schistosoma mansoni: hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene.
    Experimental parasitology, 1992, Volume: 75, Issue:4

    Topics: Animals; Crosses, Genetic; Drug Resistance; Female; Fertility; Genes, Helminth; Genes, Recessive; Hycanthone; Liver; Male; Mice; Oxamniquine; Schistosoma mansoni; Schistosomiasis mansoni

1992
Inhibition of in vitro RNA synthesis by hycanthone, oxamniquine and praziquantel.
    Experientia, 1990, May-15, Volume: 46, Issue:5

    Topics: Animals; Cell Nucleus; Cricetinae; Depression, Chemical; DNA; Hycanthone; Liver; Nitroquinolines; Oxamniquine; Praziquantel; RNA; Thioxanthenes

1990
Schistosoma mansoni-induced mesangiocapillary glomerulonephritis: influence of therapy.
    Kidney international, 1989, Volume: 35, Issue:5

    Topics: Adult; Antihypertensive Agents; Cyclophosphamide; Diet, Sodium-Restricted; Diuretics; Female; Follow-Up Studies; Glomerulonephritis, Membranoproliferative; Humans; Hycanthone; Immunosuppression Therapy; Kidney; Male; Nephrotic Syndrome; Nitroquinolines; Oxamniquine; Schistosomiasis mansoni; Thioxanthenes

1989
Resistance of schistosomes to hycanthone and oxamniquine.
    Memorias do Instituto Oswaldo Cruz, 1989, Volume: 84 Suppl 1

    Topics: Alkylation; Animals; Crosses, Genetic; DNA; Drug Resistance; Genes, Recessive; Hycanthone; Nitroquinolines; Oxamniquine; Schistosoma; Thioxanthenes

1989
Experimental chemotherapy of Schistosoma curassoni in mice.
    Parasitology research, 1989, Volume: 75, Issue:7

    Topics: Animals; Disease Models, Animal; Female; Hycanthone; Male; Mice; Nitroquinolines; Oxamniquine; Praziquantel; Schistosomiasis; Thioxanthenes; Trichlorfon

1989
Schistosoma mansoni: chemotherapy of infections of different ages.
    Experimental parasitology, 1986, Volume: 61, Issue:3

    Topics: Animals; Antimony Potassium Tartrate; Diphenylamine; Female; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Thiocyanates; Time Factors

1986
Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy.
    The American journal of pathology, 1986, Volume: 124, Issue:1

    Topics: Animals; Female; Fluorescent Antibody Technique; Hycanthone; Liver; Male; Mice; Microscopy, Electron; Oxamniquine; Parasite Egg Count; Rats; Schistosomiasis mansoni

1986
The influence of anti-parasitic therapy on the course of the glomerulopathy associated with Schistosomiasis mansoni.
    Clinical nephrology, 1987, Volume: 27, Issue:5

    Topics: Humans; Hycanthone; Kidney; Kidney Diseases; Oxamniquine; Schistosomiasis mansoni; Schistosomicides

1987
Schistosomicides and DNA functioning.
    Biochemical Society transactions, 1987, Volume: 15, Issue:1

    Topics: Animals; DNA; Female; Hycanthone; Male; Oxamniquine; Schistosoma; Schistosomicides; Structure-Activity Relationship

1987
[Genetic and molecular aspects of drug resistance in Schistosoma mansoni].
    Annali dell'Istituto superiore di sanita, 1986, Volume: 22, Issue:1

    Topics: Animals; Carbamates; Drug Resistance; HeLa Cells; Humans; Hycanthone; Oxamniquine; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides; Structure-Activity Relationship

1986
Lack of correlation between schistosomicidal and anticholinergic properties of hycanthone and related drugs.
    The Journal of parasitology, 1986, Volume: 72, Issue:4

    Topics: Animals; Carbachol; Female; Hycanthone; Lucanthone; Male; Movement; Nitroquinolines; Oxamniquine; Parasympatholytics; Schistosoma mansoni; Thioxanthenes

1986
Studies on the mode of action of oxamniquine and related schistosomicidal drugs.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Female; Hycanthone; Lucanthone; Male; Mice; Nitroquinolines; Oxamniquine; Rats; Schistosoma japonicum; Schistosoma mansoni; Schistosomicides

1985
Schistosoma mansoni: reduced efficacy of chemotherapy in infected T-cell-deprived mice.
    Experimental parasitology, 1985, Volume: 60, Issue:3

    Topics: Animals; Antilymphocyte Serum; Diphenylamine; Hycanthone; Isothiocyanates; Mice; Mice, Inbred CBA; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; T-Lymphocytes; Thiocyanates; Thymectomy

1985
Effect of chemotherapy on experimental pulmonary schistosomiasis.
    The American journal of tropical medicine and hygiene, 1983, Volume: 32, Issue:5

    Topics: Animals; Granuloma; Hycanthone; Liver; Lung; Lung Diseases, Parasitic; Male; Mice; Nitroquinolines; Oxamniquine; Pulmonary Alveoli; Schistosomiasis; Thioxanthenes

1983
Curative chemotherapy and resistance to reinfection in murine schistosomiasis.
    The American journal of tropical medicine and hygiene, 1982, Volume: 31, Issue:1

    Topics: Animals; Eosinophils; Female; Granuloma; Hycanthone; Inflammation; Liver; Macrophages; Male; Mice; Nitroquinolines; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Skin; Thioxanthenes; Time Factors

1982
Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1982, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Animals; Child; Drug Resistance; Female; Humans; Hycanthone; Isoquinolines; Mice; Nitroquinolines; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Thioxanthenes

1982
The treatment of schistosomiasis.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 7, Issue:2

    Topics: Humans; Hycanthone; Niridazole; Oxamniquine; Praziquantel; Schistosomiasis; Trichlorfon

1981
Factors affecting the acquisition of resistance against Schistosoma mansoni in the mouse. V. Reduction in the degree of resistance to reinfection after chemotherapeutic elimination of recently patent primary infections.
    Journal of helminthology, 1980, Volume: 54, Issue:1

    Topics: Animals; Antimony Potassium Tartrate; Hycanthone; Immunity, Active; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Praziquantel; Schistosoma mansoni; Schistosomiasis; Schistosomicides

1980
Susceptibility to chemotherapeutic agents of strains of Schistosoma mansoni isolated from treated and untreated patients.
    The American journal of tropical medicine and hygiene, 1980, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Animals; Child; Female; Humans; Hycanthone; Male; Mice; Niridazole; Oxamniquine; Parasite Egg Count; Schistosoma mansoni; Schistosomiasis; Species Specificity

1980
Schistosoma mansoni control in Cul de Sac Valley, Saint Lucia. II. Chemotherapy as a supplement to a focal mollusciciding programme.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980, Volume: 74, Issue:4

    Topics: Feces; Humans; Hycanthone; Molluscacides; Oxamniquine; Pest Control; Schistosoma mansoni; Schistosomiasis; West Indies

1980
Schistosoma mansoni: genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene.
    Experimental parasitology, 1993, Volume: 77, Issue:4

    Topics: Animals; Drug Resistance; Female; Genetic Complementation Test; Humans; Hycanthone; Male; Mutation; Oxamniquine; Schistosoma mansoni; Species Specificity

1993
Formation of promutagenic methylation damage in tissue-DNA of mice treated with antischistosomal agents.
    Cancer letters, 1993, Dec-20, Volume: 75, Issue:3

    Topics: Alkylation; Animals; Deoxyguanosine; DNA; DNA Damage; Hycanthone; Kidney; Liver; Male; Methylation; Mice; Mice, Inbred Strains; Oxamniquine; Schistosomicides; Spleen; Trichlorfon; Urinary Bladder

1993
Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections.
    Parasitology research, 1997, Volume: 83, Issue:7

    Topics: Animals; Biotransformation; Hycanthone; Macromolecular Substances; Male; Oxamniquine; Schistosoma haematobium; Schistosoma mansoni; Schistosomicides; Species Specificity

1997
O6-methylguanine and O6-methylguanine-DNA [corrected] methyltransferase activity in tissues of BDF-1 mice treated with antiparasitic drugs.
    Toxicology letters, 1998, Volume: 94, Issue:3

    Topics: Animals; DNA Damage; Guanine; Hycanthone; Intestines; Liver; Male; Mice; Mutagenesis; O(6)-Methylguanine-DNA Methyltransferase; Oxamniquine; Schistosomicides; Trichlorfon; Urinary Bladder

1998
Molecular basis for hycanthone drug action in schistosome parasites.
    Molecular and biochemical parasitology, 2020, Volume: 236

    Topics: Animals; Crystallization; Crystallography, X-Ray; Drug Design; Drug Resistance; Humans; Hycanthone; Oxamniquine; Praziquantel; Protein Binding; Recombinant Proteins; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Sulfotransferases

2020