oxamic acid and lactic acid

oxamic acid has been researched along with lactic acid in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's1 (3.03)18.2507
2000's11 (33.33)29.6817
2010's17 (51.52)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Chang, GG; Chiou, SH; Huang, SM1
Beitz, DC; Hood, RL; Johnson, DC1
Bereiter-Hahn, J; Tillmann, U; Vöth, M1
Cummins, R; Mooney, R; Mothersill, C; Perez, ML; Seymour, CB; Stamato, TD1
Hu, YP; Lampidis, TJ; Liu, H; Priebe, W; Savaraj, N1
Cassady, CJ; O'Regan, MH; Phillis, JW1
Deck, JA; Deck, LM; Goldberg, E; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Yu, Y1
Lampidis, TJ; Liu, H; Priebe, W; Savaraj, N1
Duan, C; Goldberg, E1
Larsen, T1
Payne, RS; Schurr, A1
Charles, PE; Comte, R; Dufour, J; Dunn-Siegrist, I; Pugin, J; Tissières, P1
Chari, M; Lam, CK; Lam, TK; Wang, PY1
Ding, Y; Fodstad, O; Khong, HT; Liu, H; Tan, M; Yu, D; Zhao, YH; Zhou, M1
Di Stefano, G; Fiume, L; Manerba, M; Vettraino, M1
Paneth, P; Swiderek, K1
Dybala-Defratyka, A; Rohr, DR; Swiderek, K1
Cui, W; Gao, D; Li, Q; Miao, DQ; Tan, JH; Wei, DL; Wu, YG; Zhou, P1
Jeon, Y; Khang, G; Kim, B; Kwon, J; Lee, D; Song, Y1
Baumann, M; Fabian, C; Kunz-Schughart, LA; Meyer, S; Mueller-Klieser, W; Sattler, UG; Yaromina, A; Zaleska, K; Zips, D1
Attwell, D; Hall, CN; Howarth, C; Klein-Flügge, MC1
Chan, O; Horblitt, A; Paranjape, SA; Sherwin, RS; Zhu, W1
Hu, Y; Huang, P; Li, X; Lu, W; Qian, C; Wen, S; Wu, W1
Chen, R; Chen, Z; Liu, X; Qiao, L; Yang, Z; Zhao, D; Zhou, Y1
Li, X; Wang, Y; Wei, DB; Wei, L; Wei, LN; Xu, LN1
Bhat, MK; Chaube, B; Malvi, P; Meena, AS; Mohammad, N; Singh, SV1
Cheng, H; Wu, M; Yan, L; Ye, W; Zhang, S; Zheng, Y1
He, Q; Huang, L; Ma, J; Zhang, Q1
Di Ianni, L; Di Stefano, G; Govoni, M; Manerba, M; Recanatini, M; Roberti, M1
Wu, MC; Ye, WR; Zhang, SS; Zheng, YJ1
Asensio, CJA; Cancio, CE; Clauzure, M; Massip-Copiz, MM; Mori, C; Santa-Coloma, TA; Valdivieso, ÁG1
Galván, EJ; Griego, E; Herrera-López, G1
Cai, W; Chen, L; Li, Y; Lin, J; Wang, C; Wu, X; Yang, X; Ye, J; Zheng, H; Zou, Q1

Other Studies

33 other study(ies) available for oxamic acid and lactic acid

ArticleYear
Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin.
    Archives of biochemistry and biophysics, 1991, Feb-01, Volume: 284, Issue:2

    Topics: Animals; Binding, Competitive; Coenzymes; Crystallins; Ducks; Heart; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxamic Acid; Pyruvates; Pyruvic Acid; Substrate Specificity; Tartronates

1991
Inhibition by potential metabolic inhibitors of in vitro adipose tissue lipogenesis.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1985, Volume: 81, Issue:3

    Topics: Acetates; Acetic Acid; Adipose Tissue; Animals; Aspartic Acid; Carbon Radioisotopes; Carboxylic Acids; Cattle; Citrates; Citric Acid; Coumaric Acids; Glucose; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Lipids; Male; Malonates; Oxamic Acid; Rats; Rats, Inbred Strains; Species Specificity

1985
Interaction of metabolic inhibitors with actin fibrils.
    Cell and tissue research, 1984, Volume: 238, Issue:1

    Topics: Actins; Actomyosin; Animals; Antimetabolites; Antimycin A; Cell Line; Fluorescent Antibody Technique; Lactates; Lactic Acid; Oxamic Acid; Oxygen Consumption; Potassium Cyanide; Rabbits; Rotenone; Xenopus laevis

1984
Involvement of energy metabolism in the production of 'bystander effects' by radiation.
    British journal of cancer, 2000, Volume: 82, Issue:10

    Topics: Animals; Apoptosis; Cell Communication; Cell Death; Cell Line; CHO Cells; Cricetinae; Culture Media, Conditioned; Energy Metabolism; Humans; Insect Repellents; Keratinocytes; L-Lactate Dehydrogenase; Lactic Acid; Organic Chemicals; Oxidation-Reduction; Radiation Tolerance

2000
Hypersensitization of tumor cells to glycolytic inhibitors.
    Biochemistry, 2001, May-08, Volume: 40, Issue:18

    Topics: Anaerobiosis; Antimycin A; Culture Media; Deoxyglucose; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glucose; Glycolysis; Growth Inhibitors; Humans; Lactic Acid; Oligomycins; Osteosarcoma; Oxamic Acid; Oxidative Phosphorylation; Rhodamine 123; Rotenone; Tumor Cells, Cultured; Uncoupling Agents

2001
Further studies on the effects of topical lactate on amino acid efflux from the ischemic rat cortex.
    Brain research, 2001, May-18, Volume: 901, Issue:1-2

    Topics: Administration, Topical; Amino Acids; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Cortex; Disease Models, Animal; Drug Interactions; Electroencephalography; Energy Metabolism; Glucose; Lactic Acid; Male; Neurons; Neuroprotective Agents; Oxamic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Physiological Phenomena

2001
Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4.
    Biochemical pharmacology, 2001, Jul-01, Volume: 62, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Energy Metabolism; Enzyme Inhibitors; Gossypol; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Molecular Sequence Data; Oxamic Acid; Sequence Homology, Amino Acid; Structure-Activity Relationship

2001
Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: a strategy for solid tumor therapy (Model C).
    Biochemical pharmacology, 2002, Dec-15, Volume: 64, Issue:12

    Topics: Antimetabolites; Cell Division; Cell Hypoxia; Deoxyglucose; Humans; Insect Repellents; Lactic Acid; Organic Chemicals; Oxygen; Tumor Cells, Cultured

2002
Inhibition of lactate dehydrogenase C4 (LDH-C4) blocks capacitation of mouse sperm in vitro.
    Cytogenetic and genome research, 2003, Volume: 103, Issue:3-4

    Topics: Animals; Enzyme Inhibitors; Glycolysis; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice; Oxamic Acid; Phosphorylation; Phosphotyrosine; Proteins; Sperm Capacitation; Spermatozoa

2003
Determination of lactate dehydrogenase (LDH) activity in milk by a fluorometric assay.
    The Journal of dairy research, 2005, Volume: 72, Issue:2

    Topics: Animals; Cattle; Copper; Fluorometry; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Logistic Models; Milk; Oxalic Acid; Oxamic Acid; Pyruvic Acid

2005
Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study.
    Neuroscience, 2007, Jul-13, Volume: 147, Issue:3

    Topics: Action Potentials; Aerobiosis; Animals; Dose-Response Relationship, Drug; Electrophysiology; Glucose; Glycolysis; Hippocampus; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Malonates; Models, Biological; Neurons; Organic Chemicals; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors

2007
Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth.
    American journal of respiratory cell and molecular biology, 2008, Volume: 38, Issue:3

    Topics: Acidosis; Acidosis, Lactic; Antimetabolites; Cell Line; Cell Survival; Colony Count, Microbial; Culture Media, Conditioned; Cyclic AMP; Deoxyglucose; Dose-Response Relationship, Drug; Epithelial Cells; Escherichia coli K12; Formazans; Glucose; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Models, Biological; Ouabain; Oxamic Acid; Pneumonia, Ventilator-Associated; Pulmonary Alveoli; Respiration, Artificial; Sodium-Potassium-Exchanging ATPase; Stress, Mechanical; Time Factors

2008
Central lactate metabolism regulates food intake.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:2

    Topics: Animals; Body Weight; Central Nervous System; Eating; Lactic Acid; Male; Oxamic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley

2008
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
    Oncogene, 2009, Oct-22, Volume: 28, Issue:42

    Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Oxamic Acid; Oxygen; Receptor, ErbB-2; RNA, Small Interfering; Transcription Factors; Transcriptional Activation; Up-Regulation

2009
Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.
    Pharmacology, 2010, Volume: 86, Issue:3

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Enzyme Inhibitors; Glucose; Glycolysis; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Lactic Acid; Oxamic Acid; Oxygen Consumption; Proto-Oncogene Proteins; Tartronates; Up-Regulation

2010
Differences and similarities in binding of pyruvate and L-lactate in the active site of M4 and H4 isoforms of human lactate dehydrogenase.
    Archives of biochemistry and biophysics, 2011, Jan-01, Volume: 505, Issue:1

    Topics: Catalytic Domain; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Models, Molecular; Oxamic Acid; Pyruvic Acid

2011
A new scheme to calculate isotope effects.
    Journal of molecular modeling, 2011, Volume: 17, Issue:9

    Topics: Algorithms; Biocatalysis; Catalytic Domain; Computer Simulation; Hydrogen Bonding; Isotopes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; NAD; Oxamic Acid; Pyruvic Acid

2011
Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential.
    Biology of reproduction, 2011, Volume: 84, Issue:6

    Topics: Animals; Cellular Senescence; Coumaric Acids; Cumulus Cells; Energy Metabolism; Female; Glucose; Lactic Acid; Mice; Oocytes; Organic Chemicals; Oxidation-Reduction; Pyruvic Acid; Rotenone

2011
Physicobiological properties and biocompatibility of biodegradable poly(oxalate-co-oxamide).
    Journal of biomedical materials research. Part A, 2011, Sep-15, Volume: 98, Issue:4

    Topics: Animals; Biocompatible Materials; Cell Line; Implants, Experimental; Lactic Acid; Macrophages; Materials Testing; Mice; Molecular Structure; Oxalates; Oxamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar

2011
Effects of three modifiers of glycolysis on ATP, lactate, hypoxia, and growth in human tumor cell lines in vivo.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2012, Volume: 188, Issue:5

    Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Coumaric Acids; Dichloroacetic Acid; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mice; Oxamic Acid; Oxygen Consumption; Transplantation, Heterologous

2012
Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Jun-27, Volume: 32, Issue:26

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Cadmium Chloride; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Models, Biological; NAD; Neurons; Organic Chemicals; Oxidative Phosphorylation; Oxygen; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Statistics, Nonparametric; Synapses; Tetrodotoxin; Valine

2012
Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.
    Diabetes, 2013, Volume: 62, Issue:12

    Topics: Animals; Bicuculline; Coumaric Acids; Diabetes Mellitus, Experimental; Diazoxide; GABA Antagonists; gamma-Aminobutyric Acid; Hypoglycemia; Insulin; Lactic Acid; Male; Microdialysis; Oxamic Acid; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus

2013
Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate.
    International journal of oncology, 2013, Volume: 43, Issue:5

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Carcinoma; Cell Cycle; Cell Proliferation; Colony-Forming Units Assay; Flow Cytometry; Glucose; Glycolysis; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oxamic Acid; Reactive Oxygen Species

2013
Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Neoplasm Invasiveness; Oxamic Acid; Stomach Neoplasms

2015
[The expression of the sperm-specific lactate dehydrogenase gene Ldh-c in plateau pika (Ochotona curzoniae) cardiac muscle and its effect on the anaerobic glycolysis].
    Sheng li xue bao : [Acta physiologica Sinica], 2015, Jun-25, Volume: 67, Issue:3

    Topics: Acclimatization; Animals; Glycolysis; Hypoxia; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Lagomorpha; Male; Myocardium; Oxamic Acid; Oxygen; RNA, Messenger

2015
Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.
    Oncotarget, 2015, Nov-10, Volume: 6, Issue:35

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Disease Progression; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Glycolysis; Humans; Hydrogen-Ion Concentration; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Male; Melanoma; Melanoma, Experimental; Metformin; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Oxamic Acid; RNA Interference; Skin Neoplasms; Time Factors; Transfection; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2015
Oxamate Improves Glycemic Control and Insulin Sensitivity via Inhibition of Tissue Lactate Production in db/db Mice.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Eating; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; L-Lactate Dehydrogenase; Lactic Acid; Lipids; Male; Mice, Inbred C57BL; Muscle, Skeletal; Oxamic Acid; Weight Gain

2016
Characterization and Inhibitor Screening of Plateau Zokor Lactate Dehydrogenase C4.
    Applied biochemistry and biotechnology, 2016, Volume: 179, Issue:6

    Topics: Animals; DNA, Complementary; Gene Expression Regulation, Enzymologic; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Oxamic Acid; Rodentia

2016
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jan-01, Volume: 96

    Topics: Caco-2 Cells; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Humans; Inflammation; Interleukin-17; Isocoumarins; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Oxamic Acid; RNA, Messenger; Tumor Necrosis Factor-alpha

2017
Oxamate Enhances the Anti-Inflammatory and Insulin-Sensitizing Effects of Metformin in Diabetic Mice.
    Pharmacology, 2017, Volume: 100, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Insulin Resistance; L-Lactate Dehydrogenase; Lactic Acid; Male; Metformin; Mice; Oxamic Acid

2017
Impairment of CFTR activity in cultured epithelial cells upregulates the expression and activity of LDH resulting in lactic acid hypersecretion.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:8

    Topics: Animals; Anthracenes; Caco-2 Cells; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Intestines; L-Lactate Dehydrogenase; Lactic Acid; Lung; Organic Chemicals; Oxamic Acid; Pyrimidines

2019
Lactate induces synapse-specific potentiation on CA3 pyramidal cells of rat hippocampus.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Animals; CA3 Region, Hippocampal; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cholera Toxin; Excitatory Postsynaptic Potentials; Lactic Acid; Male; Neuronal Plasticity; Oxamic Acid; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses

2020
LDHA mediated degradation of extracellular matrix is a potential target for the treatment of aortic dissection.
    Pharmacological research, 2022, Volume: 176

    Topics: Adult; Aged; Animals; Aorta, Thoracic; Aortic Dissection; Extracellular Matrix; Female; Glucose; Humans; Lactate Dehydrogenase 5; Lactic Acid; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Middle Aged; Muscle, Smooth, Vascular; Oxamic Acid

2022