oxamic acid and gossypol

oxamic acid has been researched along with gossypol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avery, MA; Chittiboyina, AG; Choi, SR; Hammond, NL; Pradhan, A; Tekwani, BL1
Kumar, V; Rani, R1
Fan, H; Fang, A; Huang, X; Yao, Y; Zhang, Q; Zhang, Y; Zhou, Y1
Deck, JA; Deck, LM; Goldberg, E; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Yu, Y1
Avery, MA; Desai, PV; Khan, SI; Pradhan, A; Tekwani, BL; Tripathi, AK; Walker, LA1
Granchi, C; Minutolo, F; Paterni, I; Rani, R1
Ghosh, SK; Nagaraj, VA; Subramani, PA; Sundaram, B; Varadarajan, NM1
Barreca, D; Bellocco, E; Calderaro, A; Laganá, G1
An, X; Ao, Y; He, L; Li, M; Liu, Q; Luo, X; Mamoun, CB; Nie, Z; Peng, G; Shen, Z; Sun, Y; Wang, S; Yu, L; Zhan, X; Zhao, J; Zhao, Y1

Reviews

3 review(s) available for oxamic acid and gossypol

ArticleYear
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
    Journal of medicinal chemistry, 2016, Jan-28, Volume: 59, Issue:2

    Topics: Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Neoplasms; Structure-Activity Relationship

2016
Small-molecule inhibitors of human LDH5.
    Future medicinal chemistry, 2013, Volume: 5, Issue:16

    Topics: Azoles; Carboxylic Acids; Enzyme Inhibitors; Gossypol; Humans; Indoles; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Naphthalenes; Oxamic Acid; Protein Binding; Protein Isoforms; Quinolines

2013
Lactate Dehydrogenase Inhibition: Biochemical Relevance and Therapeutical Potential.
    Current medicinal chemistry, 2019, Volume: 26, Issue:18

    Topics: Animals; Antimalarials; Azoles; Drug Discovery; Enzyme Inhibitors; Gossypol; Humans; Indoles; Isocoumarins; L-Lactate Dehydrogenase; Organic Chemicals; Plasmodium falciparum; Quinolines

2019

Other Studies

6 other study(ies) available for oxamic acid and gossypol

ArticleYear
Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors.
    Journal of medicinal chemistry, 2007, Aug-09, Volume: 50, Issue:16

    Topics: Animals; Antimalarials; Binding Sites; Cattle; Drug Design; L-Lactate Dehydrogenase; Malate Dehydrogenase; Models, Molecular; Oxamic Acid; Plasmodium falciparum; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Swine

2007
Discovery of human lactate dehydrogenase A (LDHA) inhibitors as anticancer agents to inhibit the proliferation of MG-63 osteosarcoma cells.
    MedChemComm, 2017, Aug-01, Volume: 8, Issue:8

    Topics:

2017
Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4.
    Biochemical pharmacology, 2001, Jul-01, Volume: 62, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Energy Metabolism; Enzyme Inhibitors; Gossypol; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Molecular Sequence Data; Oxamic Acid; Sequence Homology, Amino Acid; Structure-Activity Relationship

2001
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.
    European journal of biochemistry, 2004, Volume: 271, Issue:17

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Enzyme Inhibitors; Gossypol; Humans; L-Lactate Dehydrogenase; Malate Dehydrogenase; Models, Molecular; Molecular Sequence Data; Molecular Structure; Oxamic Acid; Oxidation-Reduction; Oxidoreductases; Phylogeny; Plasmodium falciparum; Protozoan Proteins; Recombinant Proteins; Sequence Alignment

2004
Purification of a recombinant histidine-tagged lactate dehydrogenase from the malaria parasite, Plasmodium vivax, and characterization of its properties.
    Biotechnology letters, 2014, Volume: 36, Issue:12

    Topics: Antibodies, Monoclonal; Antibodies, Protozoan; Chromatography, Affinity; Cloning, Molecular; Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli; Gene Expression; Gossypol; L-Lactate Dehydrogenase; Oxamic Acid; Plasmodium vivax; Recombinant Fusion Proteins

2014
Crystal structures of
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:12

    Topics: Arginine; Babesia microti; Bacterial Proteins; Catalysis; Contraceptive Agents, Male; Crystallography, X-Ray; Gossypol; L-Lactate Dehydrogenase; Models, Molecular; Organic Chemicals; Protein Conformation; Substrate Specificity

2019