oxaline has been researched along with trifluoromethanesulfonic-acid* in 1 studies
1 other study(ies) available for oxaline and trifluoromethanesulfonic-acid
| Article | Year |
|---|---|
Copper-catalyzed asymmetric synthesis of tertiary α-hydroxy phosphonic acid derivatives with in situ generated nitrosocarbonyl compounds as the oxygen source.
α-Hydroxy phosphonic acids and their derivatives are highly bioactive structural motifs. It is now reported that these compounds can be accessed through the copper-catalyzed direct α-oxidation of β-ketophosphonates using in situ generated nitrosocarbonyl compounds as an electrophilic oxygen source. These reactions proceeded in high yields (up to 95 %) and enantioselectivities (up to >99 % ee) for both cyclic as well as acyclic substrates. This method was also applied for the synthesis of α,β-dihydroxy phosphonates and β-amino-α-hydroxy phosphonates. Topics: Catalysis; Copper; Crystallography, X-Ray; Imidazoles; Mesylates; Molecular Conformation; Organophosphonates; Oxidation-Reduction; Oxygen; Stereoisomerism | 2014 |