ovalbumin has been researched along with isoalantolactone* in 1 studies
1 other study(ies) available for ovalbumin and isoalantolactone
| Article | Year |
|---|---|
Isoalantolactone alleviates ovalbumin‑induced asthmatic inflammation by reducing alternatively activated macrophage and STAT6/PPAR‑γ/KLF4 signals.
Isoalantolactone (IAL), a sesquiterpene lactone, has anti‑inflammatory activity in lipopolysaccharide (LPS)‑induced sepsis. However, it remains to be elucidated whether IAL influences asthmatic inflammation. The present study found that IAL inhibited ovalbumin (OVA)‑induced asthmatic inflammation and attenuated OVA‑induced eosinophil infiltration, immunoglobulin E generation and the production of interleukin (IL)‑4, IL‑5, C‑C motif chemokine ligand (CCL)17 and CCL22. In addition, IAL treatment with IL‑4 reduced the expression of arginase‑1, Ym‑1, CCL17 and CCL22 in bone marrow‑derived macrophages Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Chemokine CCL17; Cytokines; Female; Humans; Immunoglobulin E; Inflammation; Interleukin-4; Kruppel-Like Factor 4; Lipopolysaccharides; Lung; Macrophages; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; Sesquiterpenes; STAT6 Transcription Factor | 2021 |