ovalbumin and galactosucrose

ovalbumin has been researched along with galactosucrose* in 1 studies

Other Studies

1 other study(ies) available for ovalbumin and galactosucrose

ArticleYear
Effects of dietary lactosucrose (4G-beta-D-galactosylsucrose) on the IgE response in mice.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:11

    In this study, we examined the effects of dietary lactosucrose (LS, a non-digestible oligosaccharide) on the IgE response in mice immunized with ovalbumin (OVA)/alum. In addition to IgG1 and IgG2a responses, the anti-OVA IgE response in mice fed LS diets was dose-dependently suppressed, as compared with the control mice, while the serum total IgG levels were comparable. Moreover, dietary LS feeding inhibited antigen-specific IgE and IgG1 productions even after a second immunization. Regarding with cytokine production, when stimulated in vitro with OVA, splenocytes obtained from LS-fed mice produced a similar level of IFN-gamma, and lower levels of IL-4 and IL-5, as compared with the control mice. But IL-10 production by OVA-stimulated splenocytes was augmented in LS-fed mice, suggesting that IL-10 producing cells are responsible for the immunoregulatory effect of LS. Our findings indicate the further possibility that dietary LS supplementation can be used to prevent IgE-mediated allergic diseases.

    Topics: Adjuvants, Immunologic; Allergens; Alum Compounds; Animals; Antibody Formation; Cytokines; Dietary Carbohydrates; Hypersensitivity; Immunization; Immunoglobulin E; Immunoglobulin G; Immunosuppression Therapy; Mice; Ovalbumin; Spleen; Trisaccharides

2007